{
  "dbId" : 10912514,
  "stableId" : "R-DME-2142700",
  "displayName" : "Biosynthesis of Lipoxins (LX)",
  "nodes" : [ {
    "id" : 24640,
    "reactomeId" : 2142761,
    "displayName" : "15k-LXA4",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 782,
      "y" : 528
    },
    "minX" : 684,
    "maxX" : 829,
    "minY" : 512,
    "maxY" : 543,
    "prop" : {
      "x" : 736,
      "y" : 513,
      "width" : 92,
      "height" : 30
    },
    "textPosition" : {
      "x" : 750,
      "y" : 517
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 823,
          "y" : 518
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 823,
          "y" : 518
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 24637,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 733,
          "y" : 527
        },
        "to" : {
          "x" : 684,
          "y" : 527
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 726,
          "y" : 531
        },
        "b" : {
          "x" : 733,
          "y" : 527
        },
        "c" : {
          "x" : 726,
          "y" : 523
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 726,
          "y" : 523
        }
      }
    } ]
  }, {
    "id" : 24641,
    "reactomeId" : 73473,
    "displayName" : "NADH",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 698,
      "y" : 580
    },
    "minX" : 671,
    "maxX" : 726,
    "minY" : 527,
    "maxY" : 595,
    "prop" : {
      "x" : 671,
      "y" : 565,
      "width" : 54,
      "height" : 30
    },
    "textPosition" : {
      "x" : 676,
      "y" : 569
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 720,
          "y" : 570
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 720,
          "y" : 570
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 24637,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 694,
          "y" : 562
        },
        "to" : {
          "x" : 684,
          "y" : 527
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 688,
          "y" : 556
        },
        "b" : {
          "x" : 694,
          "y" : 562
        },
        "c" : {
          "x" : 696,
          "y" : 554
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 696,
          "y" : 554
        }
      }
    } ]
  }, {
    "id" : 24642,
    "reactomeId" : 70106,
    "displayName" : "H+",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 704,
      "y" : 490
    },
    "minX" : 684,
    "maxX" : 723,
    "minY" : 474,
    "maxY" : 527,
    "prop" : {
      "x" : 687,
      "y" : 475,
      "width" : 35,
      "height" : 30
    },
    "textPosition" : {
      "x" : 691,
      "y" : 479
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 717,
          "y" : 480
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 717,
          "y" : 480
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 24637,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 695,
          "y" : 508
        },
        "to" : {
          "x" : 684,
          "y" : 527
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 695,
          "y" : 516
        },
        "b" : {
          "x" : 695,
          "y" : 508
        },
        "c" : {
          "x" : 688,
          "y" : 512
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 688,
          "y" : 512
        }
      }
    } ],
    "trivial" : true
  }, {
    "id" : 24643,
    "reactomeId" : 10870141,
    "displayName" : "HPGD dimer",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 624,
      "y" : 465
    },
    "minX" : 578,
    "maxX" : 677,
    "minY" : 448,
    "maxY" : 519,
    "prop" : {
      "x" : 578,
      "y" : 454,
      "width" : 93,
      "height" : 22
    },
    "textPosition" : {
      "x" : 583,
      "y" : 455
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 671,
          "y" : 454
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 671,
          "y" : 454
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 24637,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 624,
          "y" : 479
        },
        "to" : {
          "x" : 624,
          "y" : 511
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 624,
          "y" : 515
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 624,
          "y" : 515
        }
      }
    } ]
  }, {
    "id" : 24638,
    "reactomeId" : 2161759,
    "displayName" : "LXA4",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 511,
      "y" : 528
    },
    "minX" : 484,
    "maxX" : 580,
    "minY" : 512,
    "maxY" : 543,
    "prop" : {
      "x" : 484,
      "y" : 513,
      "width" : 54,
      "height" : 30
    },
    "textPosition" : {
      "x" : 492,
      "y" : 517
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 533,
          "y" : 518
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 533,
          "y" : 518
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 24637,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 541,
          "y" : 527
        },
        "to" : {
          "x" : 580,
          "y" : 527
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 24639,
    "reactomeId" : 29360,
    "displayName" : "NAD+",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 569,
      "y" : 503
    },
    "minX" : 542,
    "maxX" : 597,
    "minY" : 487,
    "maxY" : 527,
    "prop" : {
      "x" : 542,
      "y" : 488,
      "width" : 54,
      "height" : 30
    },
    "textPosition" : {
      "x" : 547,
      "y" : 492
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 591,
          "y" : 493
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 591,
          "y" : 493
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 24637,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 575,
          "y" : 521
        },
        "to" : {
          "x" : 580,
          "y" : 527
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  } ],
  "edges" : [ {
    "id" : 24637,
    "reactomeId" : 10870144,
    "displayName" : "LXA4 is oxidised to 15k-LXA4 by HPGD",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 624,
      "y" : 527
    },
    "minX" : 580,
    "maxX" : 684,
    "minY" : 521,
    "maxY" : 533,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 580,
        "y" : 527
      },
      "to" : {
        "x" : 624,
        "y" : 527
      }
    }, {
      "from" : {
        "x" : 624,
        "y" : 527
      },
      "to" : {
        "x" : 684,
        "y" : 527
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 618,
        "y" : 521
      },
      "b" : {
        "x" : 630,
        "y" : 533
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 624,
        "y" : 527
      }
    },
    "inputs" : [ {
      "id" : 24638,
      "points" : [ {
        "x" : 541,
        "y" : 527
      } ]
    }, {
      "id" : 24639,
      "points" : [ {
        "x" : 575,
        "y" : 521
      } ]
    } ],
    "outputs" : [ {
      "id" : 24640,
      "points" : [ {
        "x" : 733,
        "y" : 527
      } ]
    }, {
      "id" : 24641,
      "points" : [ {
        "x" : 694,
        "y" : 562
      } ]
    }, {
      "id" : 24642,
      "points" : [ {
        "x" : 695,
        "y" : 508
      } ]
    } ],
    "catalysts" : [ {
      "id" : 24643,
      "points" : [ {
        "x" : 624,
        "y" : 479
      } ]
    } ]
  } ],
  "compartments" : [ {
    "id" : 24644,
    "reactomeId" : 70101,
    "displayName" : "cytosol",
    "schemaClass" : "Compartment",
    "renderableClass" : "Compartment",
    "position" : {
      "x" : 558,
      "y" : 420
    },
    "minX" : 0,
    "maxX" : 1117,
    "minY" : 220,
    "maxY" : 620,
    "prop" : {
      "x" : 0,
      "y" : 220,
      "width" : 1117,
      "height" : 400
    },
    "textPosition" : {
      "x" : 25,
      "y" : 548
    },
    "insets" : {
      "x" : 10,
      "y" : 230,
      "width" : 1097,
      "height" : 380
    },
    "bgColor" : {
      "r" : 250,
      "g" : 240,
      "b" : 240
    },
    "componentIds" : [ 24645, 24638, 24639, 24643, 24637, 24641, 24642, 24664, 24655, 24640 ]
  }, {
    "id" : 24645,
    "reactomeId" : 13231,
    "displayName" : "nuclear envelope",
    "schemaClass" : "Compartment",
    "renderableClass" : "Compartment",
    "position" : {
      "x" : 129,
      "y" : 445
    },
    "minX" : 61,
    "maxX" : 198,
    "minY" : 404,
    "maxY" : 486,
    "prop" : {
      "x" : 61,
      "y" : 404,
      "width" : 137,
      "height" : 82
    },
    "textPosition" : {
      "x" : 67,
      "y" : 420
    },
    "insets" : {
      "x" : 71,
      "y" : 414,
      "width" : 117,
      "height" : 62
    },
    "bgColor" : {
      "r" : 250,
      "g" : 240,
      "b" : 240
    }
  }, {
    "id" : 24654,
    "reactomeId" : 70101,
    "displayName" : "cytosol",
    "schemaClass" : "Compartment",
    "renderableClass" : "Compartment",
    "position" : {
      "x" : 511,
      "y" : 96
    },
    "minX" : 281,
    "maxX" : 741,
    "minY" : 0,
    "maxY" : 192,
    "prop" : {
      "x" : 281,
      "y" : 0,
      "width" : 460,
      "height" : 192
    },
    "textPosition" : {
      "x" : 298,
      "y" : 146
    },
    "insets" : {
      "x" : 291,
      "y" : 10,
      "width" : 440,
      "height" : 172
    },
    "bgColor" : {
      "r" : 250,
      "g" : 240,
      "b" : 240
    },
    "componentIds" : [ 24656 ]
  } ],
  "notes" : [ {
    "id" : 24656,
    "displayName" : "Platelet",
    "renderableClass" : "Note",
    "position" : {
      "x" : 328,
      "y" : 145
    },
    "minX" : 295,
    "maxX" : 362,
    "minY" : 128,
    "maxY" : 163,
    "prop" : {
      "x" : 295,
      "y" : 128,
      "width" : 67,
      "height" : 35
    },
    "textPosition" : {
      "x" : 300,
      "y" : 135
    }
  }, {
    "id" : 24655,
    "displayName" : "Neutrophil",
    "renderableClass" : "Note",
    "position" : {
      "x" : 60,
      "y" : 544
    },
    "minX" : 25,
    "maxX" : 95,
    "minY" : 529,
    "maxY" : 560,
    "prop" : {
      "x" : 25,
      "y" : 529,
      "width" : 70,
      "height" : 31
    },
    "textPosition" : {
      "x" : 25,
      "y" : 527
    }
  } ],
  "links" : [ ],
  "shadows" : [ ],
  "minX" : 0,
  "maxX" : 1117,
  "minY" : 0,
  "maxY" : 620,
  "disease" : false
}