{
  "dbId" : 11050916,
  "stableId" : "R-DDI-9755088",
  "displayName" : "Ribavirin ADME",
  "nodes" : [ {
    "id" : 94208,
    "reactomeId" : 9680963,
    "displayName" : "RBV",
    "schemaClass" : "ChemicalDrug",
    "renderableClass" : "ChemicalDrug",
    "position" : {
      "x" : 302,
      "y" : 220
    },
    "minX" : 282,
    "maxX" : 460,
    "minY" : 142,
    "maxY" : 236,
    "prop" : {
      "x" : 282,
      "y" : 205,
      "width" : 40,
      "height" : 31
    },
    "textPosition" : {
      "x" : 286,
      "y" : 210
    },
    "bgColor" : {
      "r" : 184,
      "g" : 154,
      "b" : 230
    },
    "fgColor" : {
      "r" : 161,
      "g" : 1,
      "b" : 2
    },
    "connectors" : [ {
      "edgeId" : 94225,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 325,
          "y" : 219
        },
        "to" : {
          "x" : 458,
          "y" : 213
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 94229,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 301,
          "y" : 202
        },
        "to" : {
          "x" : 301,
          "y" : 142
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 94220,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 325,
          "y" : 221
        },
        "to" : {
          "x" : 460,
          "y" : 233
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 94206,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 94211,
    "reactomeId" : 9754951,
    "displayName" : "RBV-TP",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 1105,
      "y" : 220
    },
    "minX" : 1027,
    "maxX" : 1136,
    "minY" : 204,
    "maxY" : 314,
    "prop" : {
      "x" : 1076,
      "y" : 205,
      "width" : 59,
      "height" : 31
    },
    "textPosition" : {
      "x" : 1080,
      "y" : 210
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1130,
          "y" : 210
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1130,
          "y" : 210
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 94209,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1104,
          "y" : 239
        },
        "to" : {
          "x" : 1104,
          "y" : 285
        }
      }, {
        "from" : {
          "x" : 1104,
          "y" : 285
        },
        "to" : {
          "x" : 1103,
          "y" : 314
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 94215,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 1073,
          "y" : 219
        },
        "to" : {
          "x" : 1027,
          "y" : 219
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 1066,
          "y" : 223
        },
        "b" : {
          "x" : 1073,
          "y" : 219
        },
        "c" : {
          "x" : 1066,
          "y" : 215
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 1066,
          "y" : 215
        }
      }
    } ]
  }, {
    "id" : 94210,
    "reactomeId" : 29356,
    "displayName" : "H2O",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 1042,
      "y" : 409
    },
    "minX" : 1021,
    "maxX" : 1105,
    "minY" : 314,
    "maxY" : 461,
    "prop" : {
      "x" : 1021,
      "y" : 394,
      "width" : 43,
      "height" : 31
    },
    "textPosition" : {
      "x" : 1025,
      "y" : 399
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1059,
          "y" : 399
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1059,
          "y" : 399
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 94209,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1051,
          "y" : 391
        },
        "to" : {
          "x" : 1103,
          "y" : 314
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 94238,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1060,
          "y" : 428
        },
        "to" : {
          "x" : 1105,
          "y" : 461
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ],
    "trivial" : true
  }, {
    "id" : 94213,
    "reactomeId" : 9755028,
    "displayName" : "RBV-MP",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 1105,
      "y" : 408
    },
    "minX" : 1075,
    "maxX" : 1137,
    "minY" : 370,
    "maxY" : 461,
    "prop" : {
      "x" : 1075,
      "y" : 393,
      "width" : 61,
      "height" : 31
    },
    "textPosition" : {
      "x" : 1078,
      "y" : 398
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1131,
          "y" : 398
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1131,
          "y" : 398
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 94209,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 1104,
          "y" : 390
        },
        "to" : {
          "x" : 1104,
          "y" : 370
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 1100,
          "y" : 383
        },
        "b" : {
          "x" : 1104,
          "y" : 390
        },
        "c" : {
          "x" : 1108,
          "y" : 383
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 1108,
          "y" : 383
        }
      }
    }, {
      "edgeId" : 94238,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1105,
          "y" : 427
        },
        "to" : {
          "x" : 1105,
          "y" : 461
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 94212,
    "reactomeId" : 111294,
    "displayName" : "PPi",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 1179,
      "y" : 400
    },
    "minX" : 1104,
    "maxX" : 1197,
    "minY" : 370,
    "maxY" : 416,
    "prop" : {
      "x" : 1162,
      "y" : 385,
      "width" : 34,
      "height" : 31
    },
    "textPosition" : {
      "x" : 1165,
      "y" : 390
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1191,
          "y" : 390
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1191,
          "y" : 390
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 94209,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 1159,
          "y" : 393
        },
        "to" : {
          "x" : 1104,
          "y" : 370
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 1151,
          "y" : 394
        },
        "b" : {
          "x" : 1159,
          "y" : 393
        },
        "c" : {
          "x" : 1154,
          "y" : 387
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 1154,
          "y" : 387
        }
      }
    } ]
  }, {
    "id" : 94214,
    "reactomeId" : 11019993,
    "displayName" : "ITPA dimer",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 1182,
      "y" : 345
    },
    "minX" : 1112,
    "maxX" : 1225,
    "minY" : 328,
    "maxY" : 357,
    "prop" : {
      "x" : 1146,
      "y" : 334,
      "width" : 73,
      "height" : 23
    },
    "textPosition" : {
      "x" : 1146,
      "y" : 336
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1219,
          "y" : 334
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1219,
          "y" : 334
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 94209,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 1143,
          "y" : 345
        },
        "to" : {
          "x" : 1120,
          "y" : 346
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 1116,
          "y" : 346
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1116,
          "y" : 346
        }
      }
    } ]
  }, {
    "id" : 94217,
    "reactomeId" : 9754985,
    "displayName" : "RBV-DP",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 848,
      "y" : 222
    },
    "minX" : 818,
    "maxX" : 923,
    "minY" : 206,
    "maxY" : 238,
    "prop" : {
      "x" : 818,
      "y" : 207,
      "width" : 60,
      "height" : 31
    },
    "textPosition" : {
      "x" : 821,
      "y" : 212
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 873,
          "y" : 212
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 873,
          "y" : 212
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 94215,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 881,
          "y" : 220
        },
        "to" : {
          "x" : 923,
          "y" : 219
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 94216,
    "reactomeId" : 113592,
    "displayName" : "ATP",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 897,
      "y" : 182
    },
    "minX" : 877,
    "maxX" : 923,
    "minY" : 166,
    "maxY" : 219,
    "prop" : {
      "x" : 877,
      "y" : 167,
      "width" : 40,
      "height" : 31
    },
    "textPosition" : {
      "x" : 881,
      "y" : 172
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 912,
          "y" : 172
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 912,
          "y" : 172
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 94215,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 907,
          "y" : 201
        },
        "to" : {
          "x" : 923,
          "y" : 219
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 94219,
    "reactomeId" : 11012773,
    "displayName" : "NME1,2 hexamers",
    "schemaClass" : "DefinedSet",
    "renderableClass" : "EntitySet",
    "position" : {
      "x" : 967,
      "y" : 141
    },
    "minX" : 909,
    "maxX" : 1025,
    "minY" : 130,
    "maxY" : 211,
    "prop" : {
      "x" : 909,
      "y" : 130,
      "width" : 116,
      "height" : 23
    },
    "textPosition" : {
      "x" : 932,
      "y" : 124
    },
    "connectors" : [ {
      "edgeId" : 94215,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 967,
          "y" : 159
        },
        "to" : {
          "x" : 967,
          "y" : 203
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 967,
          "y" : 207
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 967,
          "y" : 207
        }
      }
    } ]
  }, {
    "id" : 94218,
    "reactomeId" : 29370,
    "displayName" : "ADP",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 1059,
      "y" : 179
    },
    "minX" : 1027,
    "maxX" : 1081,
    "minY" : 163,
    "maxY" : 219,
    "prop" : {
      "x" : 1039,
      "y" : 164,
      "width" : 41,
      "height" : 31
    },
    "textPosition" : {
      "x" : 1043,
      "y" : 169
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1075,
          "y" : 169
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1075,
          "y" : 169
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 94215,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 1046,
          "y" : 198
        },
        "to" : {
          "x" : 1027,
          "y" : 219
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 1044,
          "y" : 206
        },
        "b" : {
          "x" : 1046,
          "y" : 198
        },
        "c" : {
          "x" : 1038,
          "y" : 200
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 1038,
          "y" : 200
        }
      }
    } ]
  }, {
    "id" : 94221,
    "reactomeId" : 113592,
    "displayName" : "ATP",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 430,
      "y" : 268
    },
    "minX" : 410,
    "maxX" : 460,
    "minY" : 233,
    "maxY" : 284,
    "prop" : {
      "x" : 410,
      "y" : 253,
      "width" : 40,
      "height" : 31
    },
    "textPosition" : {
      "x" : 414,
      "y" : 258
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 445,
          "y" : 258
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 445,
          "y" : 258
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 94220,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 443,
          "y" : 250
        },
        "to" : {
          "x" : 460,
          "y" : 233
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 94223,
    "reactomeId" : 29370,
    "displayName" : "ADP",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 599,
      "y" : 273
    },
    "minX" : 553,
    "maxX" : 621,
    "minY" : 236,
    "maxY" : 289,
    "prop" : {
      "x" : 579,
      "y" : 258,
      "width" : 41,
      "height" : 31
    },
    "textPosition" : {
      "x" : 583,
      "y" : 263
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 615,
          "y" : 263
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 615,
          "y" : 263
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 94220,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 579,
          "y" : 255
        },
        "to" : {
          "x" : 553,
          "y" : 236
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 571,
          "y" : 254
        },
        "b" : {
          "x" : 579,
          "y" : 255
        },
        "c" : {
          "x" : 576,
          "y" : 248
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 576,
          "y" : 248
        }
      }
    } ]
  }, {
    "id" : 94222,
    "reactomeId" : 9755028,
    "displayName" : "RBV-MP",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 656,
      "y" : 222
    },
    "minX" : 550,
    "maxX" : 688,
    "minY" : 206,
    "maxY" : 238,
    "prop" : {
      "x" : 626,
      "y" : 207,
      "width" : 61,
      "height" : 31
    },
    "textPosition" : {
      "x" : 629,
      "y" : 212
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 682,
          "y" : 212
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 682,
          "y" : 212
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 94225,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 623,
          "y" : 218
        },
        "to" : {
          "x" : 550,
          "y" : 211
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 616,
          "y" : 221
        },
        "b" : {
          "x" : 623,
          "y" : 218
        },
        "c" : {
          "x" : 616,
          "y" : 213
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 616,
          "y" : 213
        }
      }
    }, {
      "edgeId" : 94220,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 623,
          "y" : 226
        },
        "to" : {
          "x" : 553,
          "y" : 236
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 617,
          "y" : 231
        },
        "b" : {
          "x" : 623,
          "y" : 226
        },
        "c" : {
          "x" : 616,
          "y" : 223
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 616,
          "y" : 223
        }
      }
    } ]
  }, {
    "id" : 94224,
    "reactomeId" : 11002020,
    "displayName" : "ADK",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 514,
      "y" : 280
    },
    "minX" : 497,
    "maxX" : 537,
    "minY" : 244,
    "maxY" : 292,
    "prop" : {
      "x" : 497,
      "y" : 269,
      "width" : 34,
      "height" : 23
    },
    "textPosition" : {
      "x" : 498,
      "y" : 271
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 531,
          "y" : 269
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 531,
          "y" : 269
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 94220,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 514,
          "y" : 266
        },
        "to" : {
          "x" : 514,
          "y" : 252
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 514,
          "y" : 248
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 514,
          "y" : 248
        }
      }
    } ]
  }, {
    "id" : 94227,
    "reactomeId" : 83927,
    "displayName" : "Ino",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 600,
      "y" : 179
    },
    "minX" : 550,
    "maxX" : 618,
    "minY" : 163,
    "maxY" : 211,
    "prop" : {
      "x" : 583,
      "y" : 164,
      "width" : 34,
      "height" : 31
    },
    "textPosition" : {
      "x" : 586,
      "y" : 169
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 612,
          "y" : 169
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 612,
          "y" : 169
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 94225,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 580,
          "y" : 189
        },
        "to" : {
          "x" : 550,
          "y" : 211
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 577,
          "y" : 196
        },
        "b" : {
          "x" : 580,
          "y" : 189
        },
        "c" : {
          "x" : 572,
          "y" : 190
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 572,
          "y" : 190
        }
      }
    } ]
  }, {
    "id" : 94226,
    "reactomeId" : 29602,
    "displayName" : "IMP",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 431,
      "y" : 177
    },
    "minX" : 413,
    "maxX" : 458,
    "minY" : 161,
    "maxY" : 213,
    "prop" : {
      "x" : 413,
      "y" : 162,
      "width" : 37,
      "height" : 31
    },
    "textPosition" : {
      "x" : 417,
      "y" : 167
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 445,
          "y" : 167
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 445,
          "y" : 167
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 94225,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 442,
          "y" : 196
        },
        "to" : {
          "x" : 458,
          "y" : 213
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 94228,
    "reactomeId" : 11000768,
    "displayName" : "NT5C2 tetramer",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 513,
      "y" : 148
    },
    "minX" : 461,
    "maxX" : 571,
    "minY" : 131,
    "maxY" : 202,
    "prop" : {
      "x" : 461,
      "y" : 137,
      "width" : 104,
      "height" : 23
    },
    "textPosition" : {
      "x" : 481,
      "y" : 125
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 565,
          "y" : 137
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 565,
          "y" : 137
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 94225,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 513,
          "y" : 163
        },
        "to" : {
          "x" : 513,
          "y" : 194
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 513,
          "y" : 198
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 513,
          "y" : 198
        }
      }
    } ]
  }, {
    "id" : 94231,
    "reactomeId" : 31633,
    "displayName" : "NH4+",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 373,
      "y" : 72
    },
    "minX" : 302,
    "maxX" : 400,
    "minY" : 56,
    "maxY" : 88,
    "prop" : {
      "x" : 348,
      "y" : 57,
      "width" : 51,
      "height" : 31
    },
    "textPosition" : {
      "x" : 351,
      "y" : 62
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 394,
          "y" : 62
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 394,
          "y" : 62
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 94229,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 345,
          "y" : 77
        },
        "to" : {
          "x" : 302,
          "y" : 88
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 339,
          "y" : 83
        },
        "b" : {
          "x" : 345,
          "y" : 77
        },
        "c" : {
          "x" : 337,
          "y" : 75
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 337,
          "y" : 75
        }
      }
    } ]
  }, {
    "id" : 94230,
    "reactomeId" : 29356,
    "displayName" : "H2O",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 347,
      "y" : 163
    },
    "minX" : 301,
    "maxX" : 370,
    "minY" : 142,
    "maxY" : 179,
    "prop" : {
      "x" : 326,
      "y" : 148,
      "width" : 43,
      "height" : 31
    },
    "textPosition" : {
      "x" : 330,
      "y" : 153
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 364,
          "y" : 153
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 364,
          "y" : 153
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 94229,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 323,
          "y" : 153
        },
        "to" : {
          "x" : 301,
          "y" : 142
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ],
    "trivial" : true
  }, {
    "id" : 94233,
    "reactomeId" : 11000748,
    "displayName" : "ADA",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 361,
      "y" : 114
    },
    "minX" : 310,
    "maxX" : 384,
    "minY" : 97,
    "maxY" : 126,
    "prop" : {
      "x" : 344,
      "y" : 103,
      "width" : 34,
      "height" : 23
    },
    "textPosition" : {
      "x" : 344,
      "y" : 104
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 378,
          "y" : 103
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 378,
          "y" : 103
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 94229,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 341,
          "y" : 114
        },
        "to" : {
          "x" : 318,
          "y" : 115
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 314,
          "y" : 115
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 314,
          "y" : 115
        }
      }
    } ]
  }, {
    "id" : 94232,
    "reactomeId" : 9755025,
    "displayName" : "RBV-COOH",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 302,
      "y" : 39
    },
    "minX" : 263,
    "maxX" : 343,
    "minY" : 23,
    "maxY" : 88,
    "prop" : {
      "x" : 263,
      "y" : 24,
      "width" : 79,
      "height" : 31
    },
    "textPosition" : {
      "x" : 267,
      "y" : 29
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 337,
          "y" : 29
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 337,
          "y" : 29
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 94229,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 302,
          "y" : 58
        },
        "to" : {
          "x" : 302,
          "y" : 88
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 306,
          "y" : 65
        },
        "b" : {
          "x" : 302,
          "y" : 58
        },
        "c" : {
          "x" : 298,
          "y" : 65
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 298,
          "y" : 65
        }
      }
    } ]
  }, {
    "id" : 94235,
    "reactomeId" : 9754954,
    "displayName" : "RBV,RBV-TP",
    "schemaClass" : "DefinedSet",
    "renderableClass" : "EntitySetDrug",
    "position" : {
      "x" : 585,
      "y" : 463
    },
    "minX" : 546,
    "maxX" : 624,
    "minY" : 452,
    "maxY" : 475,
    "prop" : {
      "x" : 546,
      "y" : 452,
      "width" : 78,
      "height" : 23
    },
    "textPosition" : {
      "x" : 553,
      "y" : 446
    },
    "bgColor" : {
      "r" : 184,
      "g" : 154,
      "b" : 230
    },
    "fgColor" : {
      "r" : 161,
      "g" : 1,
      "b" : 2
    },
    "connectors" : [ {
      "edgeId" : 94234,
      "type" : "INPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 94237,
    "reactomeId" : 11046128,
    "displayName" : "SLC29A3",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 656,
      "y" : 520
    },
    "minX" : 626,
    "maxX" : 693,
    "minY" : 468,
    "maxY" : 532,
    "prop" : {
      "x" : 626,
      "y" : 509,
      "width" : 61,
      "height" : 23
    },
    "textPosition" : {
      "x" : 629,
      "y" : 503
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 687,
          "y" : 509
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 687,
          "y" : 509
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 94234,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 656,
          "y" : 506
        },
        "to" : {
          "x" : 657,
          "y" : 476
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 657,
          "y" : 472
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 657,
          "y" : 472
        }
      }
    } ]
  }, {
    "id" : 94236,
    "reactomeId" : 9754996,
    "displayName" : "RBV,RBV-TP",
    "schemaClass" : "DefinedSet",
    "renderableClass" : "EntitySetDrug",
    "position" : {
      "x" : 782,
      "y" : 460
    },
    "minX" : 743,
    "maxX" : 821,
    "minY" : 449,
    "maxY" : 472,
    "prop" : {
      "x" : 743,
      "y" : 449,
      "width" : 78,
      "height" : 23
    },
    "textPosition" : {
      "x" : 750,
      "y" : 443
    },
    "bgColor" : {
      "r" : 184,
      "g" : 154,
      "b" : 230
    },
    "fgColor" : {
      "r" : 161,
      "g" : 1,
      "b" : 2
    },
    "connectors" : [ {
      "edgeId" : 94234,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 94239,
    "reactomeId" : 9755011,
    "displayName" : "phosphate",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 1178,
      "y" : 547
    },
    "minX" : 1105,
    "maxX" : 1218,
    "minY" : 523,
    "maxY" : 563,
    "prop" : {
      "x" : 1139,
      "y" : 532,
      "width" : 78,
      "height" : 31
    },
    "textPosition" : {
      "x" : 1140,
      "y" : 537
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1212,
          "y" : 537
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1212,
          "y" : 537
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 94238,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 1136,
          "y" : 534
        },
        "to" : {
          "x" : 1105,
          "y" : 523
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 1128,
          "y" : 535
        },
        "b" : {
          "x" : 1136,
          "y" : 534
        },
        "c" : {
          "x" : 1131,
          "y" : 528
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 1131,
          "y" : 528
        }
      }
    } ],
    "trivial" : true
  }, {
    "id" : 94240,
    "reactomeId" : 11000768,
    "displayName" : "NT5C2 tetramer",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 1196,
      "y" : 491
    },
    "minX" : 1113,
    "maxX" : 1254,
    "minY" : 474,
    "maxY" : 503,
    "prop" : {
      "x" : 1144,
      "y" : 480,
      "width" : 104,
      "height" : 23
    },
    "textPosition" : {
      "x" : 1164,
      "y" : 468
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1248,
          "y" : 480
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1248,
          "y" : 480
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 94238,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 1141,
          "y" : 491
        },
        "to" : {
          "x" : 1121,
          "y" : 491
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 1117,
          "y" : 491
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1117,
          "y" : 491
        }
      }
    } ]
  }, {
    "id" : 94203,
    "reactomeId" : 9680963,
    "displayName" : "RBV",
    "schemaClass" : "ChemicalDrug",
    "renderableClass" : "ChemicalDrug",
    "position" : {
      "x" : 1106,
      "y" : 577
    },
    "minX" : 1086,
    "maxX" : 1126,
    "minY" : 523,
    "maxY" : 593,
    "prop" : {
      "x" : 1086,
      "y" : 562,
      "width" : 40,
      "height" : 31
    },
    "textPosition" : {
      "x" : 1090,
      "y" : 567
    },
    "bgColor" : {
      "r" : 184,
      "g" : 154,
      "b" : 230
    },
    "fgColor" : {
      "r" : 161,
      "g" : 1,
      "b" : 2
    },
    "connectors" : [ {
      "edgeId" : 94202,
      "type" : "INPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 94238,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 1105,
          "y" : 559
        },
        "to" : {
          "x" : 1105,
          "y" : 523
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 1101,
          "y" : 552
        },
        "b" : {
          "x" : 1105,
          "y" : 559
        },
        "c" : {
          "x" : 1109,
          "y" : 552
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 1109,
          "y" : 552
        }
      }
    } ]
  }, {
    "id" : 94205,
    "reactomeId" : 11001999,
    "displayName" : "SLC29A1",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 155,
      "y" : 312
    },
    "minX" : 125,
    "maxX" : 1097,
    "minY" : 272,
    "maxY" : 647,
    "prop" : {
      "x" : 125,
      "y" : 301,
      "width" : 61,
      "height" : 23
    },
    "textPosition" : {
      "x" : 128,
      "y" : 295
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 186,
          "y" : 301
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 186,
          "y" : 301
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 94202,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 155,
          "y" : 327
        },
        "to" : {
          "x" : 180,
          "y" : 617
        }
      }, {
        "from" : {
          "x" : 180,
          "y" : 617
        },
        "to" : {
          "x" : 1089,
          "y" : 643
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 1093,
          "y" : 643
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1093,
          "y" : 643
        }
      }
    }, {
      "edgeId" : 94206,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 155,
          "y" : 298
        },
        "to" : {
          "x" : 156,
          "y" : 280
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 156,
          "y" : 276
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 156,
          "y" : 276
        }
      }
    } ]
  }, {
    "id" : 94204,
    "reactomeId" : 9755082,
    "displayName" : "RBV",
    "schemaClass" : "ChemicalDrug",
    "renderableClass" : "ChemicalDrug",
    "position" : {
      "x" : 1105,
      "y" : 715
    },
    "minX" : 1085,
    "maxX" : 1125,
    "minY" : 700,
    "maxY" : 731,
    "prop" : {
      "x" : 1085,
      "y" : 700,
      "width" : 40,
      "height" : 31
    },
    "textPosition" : {
      "x" : 1089,
      "y" : 705
    },
    "bgColor" : {
      "r" : 184,
      "g" : 154,
      "b" : 230
    },
    "fgColor" : {
      "r" : 161,
      "g" : 1,
      "b" : 2
    },
    "connectors" : [ {
      "edgeId" : 94202,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 94207,
    "reactomeId" : 9755082,
    "displayName" : "RBV",
    "schemaClass" : "ChemicalDrug",
    "renderableClass" : "ChemicalDrug",
    "position" : {
      "x" : 20,
      "y" : 220
    },
    "minX" : 0,
    "maxX" : 40,
    "minY" : 205,
    "maxY" : 236,
    "prop" : {
      "x" : 0,
      "y" : 205,
      "width" : 40,
      "height" : 31
    },
    "textPosition" : {
      "x" : 4,
      "y" : 210
    },
    "bgColor" : {
      "r" : 184,
      "g" : 154,
      "b" : 230
    },
    "fgColor" : {
      "r" : 161,
      "g" : 1,
      "b" : 2
    },
    "connectors" : [ {
      "edgeId" : 94206,
      "type" : "INPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  } ],
  "edges" : [ {
    "id" : 94225,
    "reactomeId" : 11046126,
    "displayName" : "NT5C2 tetramer phosphorylates RBV",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 513,
      "y" : 210
    },
    "minX" : 458,
    "maxX" : 550,
    "minY" : 204,
    "maxY" : 216,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 458,
        "y" : 213
      },
      "to" : {
        "x" : 513,
        "y" : 210
      }
    }, {
      "from" : {
        "x" : 513,
        "y" : 210
      },
      "to" : {
        "x" : 550,
        "y" : 211
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 507,
        "y" : 204
      },
      "b" : {
        "x" : 519,
        "y" : 216
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 513,
        "y" : 210
      }
    },
    "inputs" : [ {
      "id" : 94226,
      "points" : [ {
        "x" : 442,
        "y" : 196
      } ]
    }, {
      "id" : 94208,
      "points" : [ {
        "x" : 325,
        "y" : 219
      } ]
    } ],
    "outputs" : [ {
      "id" : 94227,
      "points" : [ {
        "x" : 580,
        "y" : 189
      } ]
    }, {
      "id" : 94222,
      "points" : [ {
        "x" : 623,
        "y" : 218
      } ]
    } ],
    "catalysts" : [ {
      "id" : 94228,
      "points" : [ {
        "x" : 513,
        "y" : 163
      } ]
    } ]
  }, {
    "id" : 94209,
    "reactomeId" : 11046143,
    "displayName" : "ITPA dimer dephosphorylates RBV-TP to RBV-MP",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 1104,
      "y" : 346
    },
    "minX" : 1098,
    "maxX" : 1110,
    "minY" : 314,
    "maxY" : 370,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 1103,
        "y" : 314
      },
      "to" : {
        "x" : 1104,
        "y" : 346
      }
    }, {
      "from" : {
        "x" : 1104,
        "y" : 346
      },
      "to" : {
        "x" : 1104,
        "y" : 370
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 1098,
        "y" : 340
      },
      "b" : {
        "x" : 1110,
        "y" : 352
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 1104,
        "y" : 346
      }
    },
    "inputs" : [ {
      "id" : 94210,
      "points" : [ {
        "x" : 1051,
        "y" : 391
      } ]
    }, {
      "id" : 94211,
      "points" : [ {
        "x" : 1104,
        "y" : 239
      }, {
        "x" : 1104,
        "y" : 285
      } ]
    } ],
    "outputs" : [ {
      "id" : 94212,
      "points" : [ {
        "x" : 1159,
        "y" : 393
      } ]
    }, {
      "id" : 94213,
      "points" : [ {
        "x" : 1104,
        "y" : 390
      } ]
    } ],
    "catalysts" : [ {
      "id" : 94214,
      "points" : [ {
        "x" : 1143,
        "y" : 345
      } ]
    } ]
  }, {
    "id" : 94229,
    "reactomeId" : 11046133,
    "displayName" : "ADA deamidates RBV",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 302,
      "y" : 115
    },
    "minX" : 296,
    "maxX" : 308,
    "minY" : 88,
    "maxY" : 142,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 301,
        "y" : 142
      },
      "to" : {
        "x" : 302,
        "y" : 115
      }
    }, {
      "from" : {
        "x" : 302,
        "y" : 115
      },
      "to" : {
        "x" : 302,
        "y" : 88
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 296,
        "y" : 109
      },
      "b" : {
        "x" : 308,
        "y" : 121
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 302,
        "y" : 115
      }
    },
    "inputs" : [ {
      "id" : 94208,
      "points" : [ {
        "x" : 301,
        "y" : 202
      } ]
    }, {
      "id" : 94230,
      "points" : [ {
        "x" : 323,
        "y" : 153
      } ]
    } ],
    "outputs" : [ {
      "id" : 94231,
      "points" : [ {
        "x" : 345,
        "y" : 77
      } ]
    }, {
      "id" : 94232,
      "points" : [ {
        "x" : 302,
        "y" : 58
      } ]
    } ],
    "catalysts" : [ {
      "id" : 94233,
      "points" : [ {
        "x" : 341,
        "y" : 114
      } ]
    } ]
  }, {
    "id" : 94215,
    "reactomeId" : 11046137,
    "displayName" : "NME1,2 hexamers phosphorylate RBV-DP",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 967,
      "y" : 219
    },
    "minX" : 923,
    "maxX" : 1027,
    "minY" : 213,
    "maxY" : 225,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 923,
        "y" : 219
      },
      "to" : {
        "x" : 967,
        "y" : 219
      }
    }, {
      "from" : {
        "x" : 967,
        "y" : 219
      },
      "to" : {
        "x" : 1027,
        "y" : 219
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 961,
        "y" : 213
      },
      "b" : {
        "x" : 973,
        "y" : 225
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 967,
        "y" : 219
      }
    },
    "inputs" : [ {
      "id" : 94216,
      "points" : [ {
        "x" : 907,
        "y" : 201
      } ]
    }, {
      "id" : 94217,
      "points" : [ {
        "x" : 881,
        "y" : 220
      } ]
    } ],
    "outputs" : [ {
      "id" : 94211,
      "points" : [ {
        "x" : 1073,
        "y" : 219
      } ]
    }, {
      "id" : 94218,
      "points" : [ {
        "x" : 1046,
        "y" : 198
      } ]
    } ],
    "catalysts" : [ {
      "id" : 94219,
      "points" : [ {
        "x" : 967,
        "y" : 159
      } ]
    } ]
  }, {
    "id" : 94202,
    "reactomeId" : 11046145,
    "displayName" : "SLC29A1 transports RBV from cytosol to extracellular region",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 1105,
      "y" : 643
    },
    "minX" : 1099,
    "maxX" : 1111,
    "minY" : 596,
    "maxY" : 697,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 1105,
        "y" : 596
      },
      "to" : {
        "x" : 1105,
        "y" : 643
      }
    }, {
      "from" : {
        "x" : 1105,
        "y" : 643
      },
      "to" : {
        "x" : 1105,
        "y" : 697
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 1101,
        "y" : 690
      },
      "b" : {
        "x" : 1105,
        "y" : 697
      },
      "c" : {
        "x" : 1109,
        "y" : 690
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 1109,
        "y" : 690
      }
    },
    "reactionShape" : {
      "a" : {
        "x" : 1099,
        "y" : 637
      },
      "b" : {
        "x" : 1111,
        "y" : 649
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 1105,
        "y" : 643
      }
    },
    "inputs" : [ {
      "id" : 94203
    } ],
    "outputs" : [ {
      "id" : 94204
    } ],
    "catalysts" : [ {
      "id" : 94205,
      "points" : [ {
        "x" : 155,
        "y" : 327
      }, {
        "x" : 180,
        "y" : 617
      } ]
    } ]
  }, {
    "id" : 94234,
    "reactomeId" : 11046131,
    "displayName" : "SLC29A3 transports RBV,RBV-TP from cytosol to mitochondrial matrix",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 657,
      "y" : 460
    },
    "minX" : 630,
    "maxX" : 737,
    "minY" : 454,
    "maxY" : 466,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 630,
        "y" : 461
      },
      "to" : {
        "x" : 657,
        "y" : 460
      }
    }, {
      "from" : {
        "x" : 657,
        "y" : 460
      },
      "to" : {
        "x" : 737,
        "y" : 460
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 730,
        "y" : 464
      },
      "b" : {
        "x" : 737,
        "y" : 460
      },
      "c" : {
        "x" : 730,
        "y" : 456
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 730,
        "y" : 456
      }
    },
    "reactionShape" : {
      "a" : {
        "x" : 651,
        "y" : 454
      },
      "b" : {
        "x" : 663,
        "y" : 466
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 657,
        "y" : 460
      }
    },
    "inputs" : [ {
      "id" : 94235
    } ],
    "outputs" : [ {
      "id" : 94236
    } ],
    "catalysts" : [ {
      "id" : 94237,
      "points" : [ {
        "x" : 656,
        "y" : 506
      } ]
    } ]
  }, {
    "id" : 94220,
    "reactomeId" : 11046135,
    "displayName" : "ADK phosphorylates RBV",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 514,
      "y" : 236
    },
    "minX" : 460,
    "maxX" : 553,
    "minY" : 230,
    "maxY" : 242,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 460,
        "y" : 233
      },
      "to" : {
        "x" : 514,
        "y" : 236
      }
    }, {
      "from" : {
        "x" : 514,
        "y" : 236
      },
      "to" : {
        "x" : 553,
        "y" : 236
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 508,
        "y" : 230
      },
      "b" : {
        "x" : 520,
        "y" : 242
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 514,
        "y" : 236
      }
    },
    "inputs" : [ {
      "id" : 94208,
      "points" : [ {
        "x" : 325,
        "y" : 221
      } ]
    }, {
      "id" : 94221,
      "points" : [ {
        "x" : 443,
        "y" : 250
      } ]
    } ],
    "outputs" : [ {
      "id" : 94222,
      "points" : [ {
        "x" : 623,
        "y" : 226
      } ]
    }, {
      "id" : 94223,
      "points" : [ {
        "x" : 579,
        "y" : 255
      } ]
    } ],
    "catalysts" : [ {
      "id" : 94224,
      "points" : [ {
        "x" : 514,
        "y" : 266
      } ]
    } ]
  }, {
    "id" : 94206,
    "reactomeId" : 11046140,
    "displayName" : "SLC29A1 transports RBV from extracellular region to cytosol",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 156,
      "y" : 264
    },
    "minX" : 43,
    "maxX" : 279,
    "minY" : 226,
    "maxY" : 270,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 43,
        "y" : 226
      },
      "to" : {
        "x" : 156,
        "y" : 264
      }
    }, {
      "from" : {
        "x" : 156,
        "y" : 264
      },
      "to" : {
        "x" : 279,
        "y" : 226
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 274,
        "y" : 232
      },
      "b" : {
        "x" : 279,
        "y" : 226
      },
      "c" : {
        "x" : 271,
        "y" : 224
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 271,
        "y" : 224
      }
    },
    "reactionShape" : {
      "a" : {
        "x" : 150,
        "y" : 258
      },
      "b" : {
        "x" : 162,
        "y" : 270
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 156,
        "y" : 264
      }
    },
    "inputs" : [ {
      "id" : 94207
    } ],
    "outputs" : [ {
      "id" : 94208
    } ],
    "catalysts" : [ {
      "id" : 94205,
      "points" : [ {
        "x" : 155,
        "y" : 298
      } ]
    } ]
  }, {
    "id" : 94238,
    "reactomeId" : 11046147,
    "displayName" : "NT5C2 tetramer dephosphorylates RBV-MP",
    "schemaClass" : "BlackBoxEvent",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 1105,
      "y" : 491
    },
    "minX" : 1099,
    "maxX" : 1111,
    "minY" : 461,
    "maxY" : 523,
    "reactionType" : "omitted",
    "segments" : [ {
      "from" : {
        "x" : 1105,
        "y" : 461
      },
      "to" : {
        "x" : 1105,
        "y" : 491
      }
    }, {
      "from" : {
        "x" : 1105,
        "y" : 491
      },
      "to" : {
        "x" : 1105,
        "y" : 523
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 1099,
        "y" : 485
      },
      "b" : {
        "x" : 1111,
        "y" : 497
      },
      "s" : "\\\\",
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 1105,
        "y" : 491
      }
    },
    "inputs" : [ {
      "id" : 94213,
      "points" : [ {
        "x" : 1105,
        "y" : 427
      } ]
    }, {
      "id" : 94210,
      "points" : [ {
        "x" : 1060,
        "y" : 428
      } ]
    } ],
    "outputs" : [ {
      "id" : 94203,
      "points" : [ {
        "x" : 1105,
        "y" : 559
      } ]
    }, {
      "id" : 94239,
      "points" : [ {
        "x" : 1136,
        "y" : 534
      } ]
    } ],
    "catalysts" : [ {
      "id" : 94240,
      "points" : [ {
        "x" : 1141,
        "y" : 491
      } ]
    } ]
  } ],
  "compartments" : [ {
    "id" : 94245,
    "reactomeId" : 70101,
    "displayName" : "cytosol",
    "schemaClass" : "Compartment",
    "renderableClass" : "Compartment",
    "position" : {
      "x" : 715,
      "y" : 323
    },
    "minX" : 150,
    "maxX" : 1280,
    "minY" : 0,
    "maxY" : 646,
    "prop" : {
      "x" : 150,
      "y" : 0,
      "width" : 1130,
      "height" : 646
    },
    "textPosition" : {
      "x" : 179,
      "y" : 14
    },
    "insets" : {
      "x" : 160,
      "y" : 10,
      "width" : 1110,
      "height" : 626
    },
    "bgColor" : {
      "r" : 250,
      "g" : 240,
      "b" : 240
    },
    "componentIds" : [ 94216, 94202, 94210, 94206, 94225, 94212, 94208, 94232, 94227, 94211, 94209, 94215, 94217, 94220, 94219, 94226, 94228, 94218, 94229, 94214, 94224, 94233, 94231, 94203, 94230, 94221, 94213, 94205, 94252, 94253, 94235, 94234, 94249, 94222, 94223, 94251, 94239, 94238, 94240 ]
  }, {
    "id" : 94249,
    "reactomeId" : 17927,
    "displayName" : "mitochondrial intermembrane space",
    "schemaClass" : "Compartment",
    "renderableClass" : "Compartment",
    "position" : {
      "x" : 797,
      "y" : 441
    },
    "minX" : 663,
    "maxX" : 932,
    "minY" : 315,
    "maxY" : 568,
    "prop" : {
      "x" : 663,
      "y" : 315,
      "width" : 269,
      "height" : 253
    },
    "textPosition" : {
      "x" : 676,
      "y" : 327
    },
    "insets" : {
      "x" : 673,
      "y" : 325,
      "width" : 249,
      "height" : 233
    },
    "bgColor" : {
      "r" : 250,
      "g" : 240,
      "b" : 240
    },
    "componentIds" : [ 94250, 94237 ]
  }, {
    "id" : 94250,
    "reactomeId" : 5460,
    "displayName" : "mitochondrial matrix",
    "schemaClass" : "Compartment",
    "renderableClass" : "Compartment",
    "position" : {
      "x" : 804,
      "y" : 451
    },
    "minX" : 692,
    "maxX" : 917,
    "minY" : 366,
    "maxY" : 536,
    "prop" : {
      "x" : 692,
      "y" : 366,
      "width" : 225,
      "height" : 170
    },
    "textPosition" : {
      "x" : 705,
      "y" : 381
    },
    "insets" : {
      "x" : 702,
      "y" : 376,
      "width" : 205,
      "height" : 150
    },
    "bgColor" : {
      "r" : 250,
      "g" : 240,
      "b" : 240
    },
    "componentIds" : [ 94236 ]
  } ],
  "notes" : [ ],
  "links" : [ {
    "id" : 94251,
    "renderableClass" : "EntitySetAndMemberLink",
    "position" : {
      "x" : 636,
      "y" : 302
    },
    "minX" : 588,
    "maxX" : 1073,
    "minY" : 225,
    "maxY" : 446,
    "segments" : [ {
      "from" : {
        "x" : 1073,
        "y" : 225
      },
      "to" : {
        "x" : 636,
        "y" : 302
      }
    }, {
      "from" : {
        "x" : 636,
        "y" : 302
      },
      "to" : {
        "x" : 588,
        "y" : 446
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 630,
        "y" : 296
      },
      "b" : {
        "x" : 642,
        "y" : 308
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 636,
        "y" : 302
      }
    },
    "inputs" : [ {
      "id" : 94211
    } ],
    "outputs" : [ {
      "id" : 94235
    } ]
  }, {
    "id" : 94253,
    "renderableClass" : "EntitySetAndMemberLink",
    "position" : {
      "x" : 756,
      "y" : 595
    },
    "minX" : 584,
    "maxX" : 1083,
    "minY" : 481,
    "maxY" : 601,
    "segments" : [ {
      "from" : {
        "x" : 1083,
        "y" : 579
      },
      "to" : {
        "x" : 929,
        "y" : 597
      }
    }, {
      "from" : {
        "x" : 929,
        "y" : 597
      },
      "to" : {
        "x" : 584,
        "y" : 594
      }
    }, {
      "from" : {
        "x" : 584,
        "y" : 594
      },
      "to" : {
        "x" : 584,
        "y" : 481
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 750,
        "y" : 589
      },
      "b" : {
        "x" : 762,
        "y" : 601
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 756,
        "y" : 595
      }
    },
    "inputs" : [ {
      "id" : 94203
    } ],
    "outputs" : [ {
      "id" : 94235
    } ]
  }, {
    "id" : 94252,
    "renderableClass" : "EntitySetAndMemberLink",
    "position" : {
      "x" : 517,
      "y" : 404
    },
    "minX" : 320,
    "maxX" : 571,
    "minY" : 239,
    "maxY" : 446,
    "segments" : [ {
      "from" : {
        "x" : 320,
        "y" : 239
      },
      "to" : {
        "x" : 517,
        "y" : 404
      }
    }, {
      "from" : {
        "x" : 517,
        "y" : 404
      },
      "to" : {
        "x" : 571,
        "y" : 446
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 511,
        "y" : 398
      },
      "b" : {
        "x" : 523,
        "y" : 410
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 517,
        "y" : 404
      }
    },
    "inputs" : [ {
      "id" : 94208
    } ],
    "outputs" : [ {
      "id" : 94235
    } ]
  } ],
  "shadows" : [ ],
  "minX" : 0,
  "maxX" : 1280,
  "minY" : 0,
  "maxY" : 731,
  "disease" : false
}