{
  "dbId" : 10331917,
  "stId" : "R-CFA-9793528",
  "speciesName" : "Canis familiaris",
  "nodes" : [ {
    "dbId" : 10323321,
    "stId" : "R-CFA-9794401",
    "displayName" : "ABCG2 [apical plasma membrane]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 49646,
    "identifier" : "B3RFJ1",
    "standardIdentifier" : "uniprot:B3RFJ1",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "ABCG2" ],
    "parents" : [ 10323323 ],
    "children" : [ ]
  }, {
    "dbId" : 10323323,
    "stId" : "R-CFA-9794404",
    "displayName" : "ABCG2 tetramer [apical plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 49646,
    "diagramIds" : [ 50025, 50047 ],
    "parents" : [ ],
    "children" : [ 10323321 ]
  }, {
    "dbId" : 9793566,
    "stId" : "R-ALL-9793566",
    "displayName" : "Cipro(1+) [extracellular region]",
    "schemaClass" : "SimpleEntity",
    "speciesId" : 0,
    "diagramIds" : [ 50027 ],
    "identifier" : "192486",
    "standardIdentifier" : "chebi:192486",
    "referenceType" : "ReferenceMolecule",
    "parents" : [ ],
    "children" : [ ]
  }, {
    "dbId" : 9793625,
    "stId" : "R-ALL-9793625",
    "displayName" : "Cipro [cytosol]",
    "schemaClass" : "SimpleEntity",
    "speciesId" : 0,
    "diagramIds" : [ 50021, 50038, 50043, 50029 ],
    "identifier" : "192484",
    "standardIdentifier" : "chebi:192484",
    "referenceType" : "ReferenceMolecule",
    "parents" : [ ],
    "children" : [ ]
  }, {
    "dbId" : 29356,
    "stId" : "R-ALL-29356",
    "displayName" : "H2O [cytosol]",
    "schemaClass" : "SimpleEntity",
    "speciesId" : 0,
    "diagramIds" : [ 50020, 50042 ],
    "identifier" : "15377",
    "standardIdentifier" : "chebi:15377",
    "referenceType" : "ReferenceMolecule",
    "parents" : [ ],
    "children" : [ ]
  }, {
    "dbId" : 9794119,
    "stId" : "R-ALL-9794119",
    "displayName" : "Cipro [extracellular region]",
    "schemaClass" : "SimpleEntity",
    "speciesId" : 0,
    "diagramIds" : [ 50033, 50036, 50023, 50045 ],
    "identifier" : "192484",
    "standardIdentifier" : "chebi:192484",
    "referenceType" : "ReferenceMolecule",
    "parents" : [ 10323333 ],
    "children" : [ ]
  }, {
    "dbId" : 1524165,
    "stId" : "R-ALL-1524165",
    "displayName" : "PI [cytosol]",
    "schemaClass" : "SimpleEntity",
    "speciesId" : 0,
    "diagramIds" : [ 50024, 50046 ],
    "identifier" : "57880",
    "standardIdentifier" : "chebi:57880",
    "referenceType" : "ReferenceMolecule",
    "parents" : [ ],
    "children" : [ ]
  }, {
    "dbId" : 10323339,
    "stId" : "R-CFA-9794526",
    "displayName" : "SLC22A1 [basolateral plasma membrane]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 49646,
    "diagramIds" : [ 50049, 50039 ],
    "identifier" : "A0A8I3MM56",
    "standardIdentifier" : "uniprot:A0A8I3MM56",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "SLC22A1" ],
    "parents" : [ ],
    "children" : [ ]
  }, {
    "dbId" : 10323333,
    "stId" : "R-CFA-9794443",
    "displayName" : "Cipro:ALB [extracellular region]",
    "schemaClass" : "Complex",
    "speciesId" : 49646,
    "diagramIds" : [ 50034 ],
    "parents" : [ ],
    "children" : [ 10248065, 9794119 ]
  }, {
    "dbId" : 113592,
    "stId" : "R-ALL-113592",
    "displayName" : "ATP [cytosol]",
    "schemaClass" : "SimpleEntity",
    "speciesId" : 0,
    "diagramIds" : [ 50019, 50041 ],
    "identifier" : "30616",
    "standardIdentifier" : "chebi:30616",
    "referenceType" : "ReferenceMolecule",
    "parents" : [ ],
    "children" : [ ]
  }, {
    "dbId" : 29370,
    "stId" : "R-ALL-29370",
    "displayName" : "ADP [cytosol]",
    "schemaClass" : "SimpleEntity",
    "speciesId" : 0,
    "diagramIds" : [ 50022, 50044 ],
    "identifier" : "456216",
    "standardIdentifier" : "chebi:456216",
    "referenceType" : "ReferenceMolecule",
    "parents" : [ ],
    "children" : [ ]
  }, {
    "dbId" : 70106,
    "stId" : "R-ALL-70106",
    "displayName" : "H+ [cytosol]",
    "schemaClass" : "SimpleEntity",
    "speciesId" : 0,
    "diagramIds" : [ 50028 ],
    "identifier" : "15378",
    "standardIdentifier" : "chebi:15378",
    "referenceType" : "ReferenceMolecule",
    "parents" : [ ],
    "children" : [ ]
  }, {
    "dbId" : 10248065,
    "stId" : "R-CFA-194115",
    "displayName" : "ALB [extracellular region]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 49646,
    "diagramIds" : [ 50032 ],
    "identifier" : "A0A8I3MY68",
    "standardIdentifier" : "uniprot:A0A8I3MY68",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "ALB" ],
    "parents" : [ 10323333 ],
    "children" : [ ]
  }, {
    "dbId" : 10323328,
    "stId" : "R-CFA-9794403",
    "displayName" : "SLCO1A2 [apical plasma membrane]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 49646,
    "diagramIds" : [ 50030 ],
    "identifier" : "A0A8I3NXT1",
    "standardIdentifier" : "uniprot:A0A8I3NXT1",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "SLCO1A2" ],
    "parents" : [ ],
    "children" : [ ]
  } ],
  "edges" : [ {
    "dbId" : 10323342,
    "stId" : "R-CFA-9794523",
    "displayName" : "SLC22A1 transports Cipro into renal cell",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "preceding" : [ 10323337 ],
    "inputs" : [ 9794119 ],
    "outputs" : [ 9793625 ],
    "catalysts" : [ 10323339 ],
    "efs" : [ ],
    "diagramIds" : [ 50037 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10323326,
    "stId" : "R-CFA-9794120",
    "displayName" : "ABCG2 transports Cipro from intestinal cell to extracellular space",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "inputs" : [ 29356, 9793625, 113592 ],
    "outputs" : [ 29370, 1524165, 9794119 ],
    "catalysts" : [ 10323323 ],
    "efs" : [ ],
    "diagramIds" : [ 50018 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10323337,
    "stId" : "R-CFA-9794475",
    "displayName" : "Cipro:ALB dissociates",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "preceding" : [ 10323335 ],
    "following" : [ 10323342, 10323351 ],
    "inputs" : [ 10323333 ],
    "outputs" : [ 10248065, 9794119 ],
    "efs" : [ ],
    "diagramIds" : [ 50035 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10323349,
    "stId" : "R-CFA-9794572",
    "displayName" : "ABCG2 transports Cipro from hepatic cell to extracellular space",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "preceding" : [ 10323351 ],
    "inputs" : [ 29356, 9793625, 113592 ],
    "outputs" : [ 29370, 1524165, 9794119 ],
    "catalysts" : [ 10323323 ],
    "efs" : [ ],
    "diagramIds" : [ 50040 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10323335,
    "stId" : "R-CFA-9794444",
    "displayName" : "ALB binds Cipro",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "following" : [ 10323337 ],
    "inputs" : [ 10248065, 9794119 ],
    "outputs" : [ 10323333 ],
    "efs" : [ ],
    "diagramIds" : [ 50031 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10323351,
    "stId" : "R-CFA-9795207",
    "displayName" : "SLC22A1 transports Cipro into hepatic cell",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "preceding" : [ 10323337 ],
    "following" : [ 10323349 ],
    "inputs" : [ 9794119 ],
    "outputs" : [ 9793625 ],
    "catalysts" : [ 10323339 ],
    "efs" : [ ],
    "diagramIds" : [ 50048 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10323331,
    "stId" : "R-CFA-9794270",
    "displayName" : "SLCO1A2 transports Cipro(1+) into the cytosol",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "inputs" : [ 9793566 ],
    "outputs" : [ 9793625, 70106 ],
    "catalysts" : [ 10323328 ],
    "efs" : [ ],
    "diagramIds" : [ 50026 ],
    "entityFunctionalStatus" : [ ]
  } ]
}