{
  "dbId" : 10330553,
  "stId" : "R-CFA-9707616",
  "speciesName" : "Canis familiaris",
  "nodes" : [ {
    "dbId" : 10321053,
    "stId" : "R-CFA-9708434",
    "displayName" : "BACH1:Hemes [cytosol]",
    "schemaClass" : "Complex",
    "speciesId" : 49646,
    "parents" : [ 10321055 ],
    "children" : [ 9707308, 10321051 ]
  }, {
    "dbId" : 10321055,
    "stId" : "R-CFA-9708433",
    "displayName" : "XPO1:BACH1:Hemes [cytosol]",
    "schemaClass" : "Complex",
    "speciesId" : 49646,
    "diagramIds" : [ 37023 ],
    "parents" : [ ],
    "children" : [ 10235924, 10321053 ]
  }, {
    "dbId" : 9709335,
    "stId" : "R-ALL-9709335",
    "displayName" : "CO [extracellular region]",
    "schemaClass" : "SimpleEntity",
    "speciesId" : 0,
    "identifier" : "17245",
    "standardIdentifier" : "chebi:17245",
    "referenceType" : "ReferenceMolecule",
    "parents" : [ 10320945 ],
    "children" : [ ]
  }, {
    "dbId" : 10321049,
    "stId" : "R-CFA-9708425",
    "displayName" : "XPO1:BACH1:Hemes [nucleoplasm]",
    "schemaClass" : "Complex",
    "speciesId" : 49646,
    "diagramIds" : [ 37021 ],
    "parents" : [ ],
    "children" : [ 10320964, 10238697 ]
  }, {
    "dbId" : 9707665,
    "stId" : "R-ALL-9707665",
    "displayName" : "heme [nuclear envelope]",
    "schemaClass" : "SimpleEntity",
    "speciesId" : 0,
    "identifier" : "60344",
    "standardIdentifier" : "chebi:60344",
    "referenceType" : "ReferenceMolecule",
    "parents" : [ 9707552 ],
    "children" : [ ]
  }, {
    "dbId" : 10321051,
    "stId" : "R-CFA-9708429",
    "displayName" : "BACH1 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 49646,
    "identifier" : "A0A8I3PAQ6",
    "standardIdentifier" : "uniprot:A0A8I3PAQ6",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "BACH1" ],
    "parents" : [ 10321053 ],
    "children" : [ ]
  }, {
    "dbId" : 351629,
    "stId" : "R-ALL-351629",
    "displayName" : "H2O2 [extracellular region]",
    "schemaClass" : "SimpleEntity",
    "speciesId" : 0,
    "diagramIds" : [ 36986 ],
    "identifier" : "16240",
    "standardIdentifier" : "chebi:16240",
    "referenceType" : "ReferenceMolecule",
    "parents" : [ ],
    "children" : [ ]
  }, {
    "dbId" : 10235924,
    "stId" : "R-CFA-165539",
    "displayName" : "XPO1 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 49646,
    "identifier" : "A0A8I3NNH1",
    "standardIdentifier" : "uniprot:A0A8I3NNH1",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "XPO1" ],
    "parents" : [ 10321055 ],
    "children" : [ ]
  }, {
    "dbId" : 171149,
    "stId" : "R-ALL-171149",
    "displayName" : "CHOL [extracellular region]",
    "schemaClass" : "SimpleEntity",
    "speciesId" : 0,
    "identifier" : "16113",
    "standardIdentifier" : "chebi:16113",
    "referenceType" : "ReferenceMolecule",
    "parents" : [ 10320970, 10239116, 10240052, 10247996, 10320972, 10320974 ],
    "children" : [ ]
  }, {
    "dbId" : 71185,
    "stId" : "R-ALL-71185",
    "displayName" : "ferroheme [cytosol]",
    "schemaClass" : "SimpleEntity",
    "speciesId" : 0,
    "identifier" : "60344",
    "standardIdentifier" : "chebi:60344",
    "referenceType" : "ReferenceMolecule",
    "parents" : [ 9707308 ],
    "children" : [ ]
  }, {
    "dbId" : 10239116,
    "stId" : "R-CFA-171131",
    "displayName" : "LDL [extracellular region]",
    "schemaClass" : "Complex",
    "speciesId" : 49646,
    "parents" : [ 10320968 ],
    "children" : [ 171149, 171066, 171076, 10239114, 171126 ]
  }, {
    "dbId" : 10244361,
    "stId" : "R-CFA-200673",
    "displayName" : "SLC46A1 [plasma membrane]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 49646,
    "diagramIds" : [ 37004 ],
    "identifier" : "A0A8I3N1L5",
    "standardIdentifier" : "uniprot:A0A8I3N1L5",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "SLC46A1" ],
    "parents" : [ ],
    "children" : [ ]
  }, {
    "dbId" : 10239114,
    "stId" : "R-CFA-171065",
    "displayName" : "APOB [extracellular region]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 49646,
    "identifier" : "A0A8I3S4D1",
    "standardIdentifier" : "uniprot:A0A8I3S4D1",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "APOB" ],
    "parents" : [ 10320970, 10239116 ],
    "children" : [ ]
  }, {
    "dbId" : 10247996,
    "stId" : "R-CFA-216752",
    "displayName" : "discoidal HDL [extracellular region]",
    "schemaClass" : "Complex",
    "speciesId" : 49646,
    "parents" : [ 10320968 ],
    "children" : [ 171149, 10240037, 171066 ]
  }, {
    "dbId" : 9707575,
    "stId" : "R-ALL-9707575",
    "displayName" : "Hemes [nucleoplasm]",
    "schemaClass" : "CandidateSet",
    "speciesId" : 0,
    "diagramIds" : [ 37013 ],
    "parents" : [ 10320992, 10320964 ],
    "children" : [ 1368125, 4655330 ]
  }, {
    "dbId" : 10330937,
    "stId" : "R-CFA-2173782",
    "displayName" : "Binding and Uptake of Ligands by Scavenger Receptors",
    "schemaClass" : "Pathway",
    "speciesId" : 49646,
    "diagramIds" : [ 37038 ]
  }, {
    "dbId" : 4655330,
    "stId" : "R-ALL-4655330",
    "displayName" : "heme [nucleoplasm]",
    "schemaClass" : "SimpleEntity",
    "speciesId" : 0,
    "identifier" : "60344",
    "standardIdentifier" : "chebi:60344",
    "referenceType" : "ReferenceMolecule",
    "parents" : [ 9707575 ],
    "children" : [ ]
  }, {
    "dbId" : 10320954,
    "stId" : "R-CFA-2168856",
    "displayName" : "ApoHb [extracellular region]",
    "schemaClass" : "Complex",
    "speciesId" : 49646,
    "diagramIds" : [ 36998 ],
    "parents" : [ ],
    "children" : [ 10277622, 10277626 ]
  }, {
    "dbId" : 10240052,
    "stId" : "R-CFA-265523",
    "displayName" : "spherical HDL [extracellular region]",
    "schemaClass" : "Complex",
    "speciesId" : 49646,
    "parents" : [ 10320968 ],
    "children" : [ 171149, 10240037, 171066, 171076, 171126 ]
  }, {
    "dbId" : 1368125,
    "stId" : "R-ALL-1368125",
    "displayName" : "ferriheme b [nucleoplasm]",
    "schemaClass" : "SimpleEntity",
    "speciesId" : 0,
    "diagramIds" : [ 37026 ],
    "identifier" : "36144",
    "standardIdentifier" : "chebi:36144",
    "referenceType" : "ReferenceMolecule",
    "parents" : [ 9707575 ],
    "children" : [ ]
  }, {
    "dbId" : 10320950,
    "stId" : "R-CFA-9707550",
    "displayName" : "CLEC1B dimer:Hemes [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 49646,
    "diagramIds" : [ 37001 ],
    "parents" : [ ],
    "children" : [ 9707310, 10294135 ]
  }, {
    "dbId" : 10320945,
    "stId" : "R-CFA-9709322",
    "displayName" : "COHb [extracellular region]",
    "schemaClass" : "Complex",
    "speciesId" : 49646,
    "diagramIds" : [ 36991 ],
    "parents" : [ ],
    "children" : [ 9709335, 10320943 ]
  }, {
    "dbId" : 917795,
    "stId" : "R-ALL-917795",
    "displayName" : "FeHM [cytosol]",
    "schemaClass" : "SimpleEntity",
    "speciesId" : 0,
    "identifier" : "36144",
    "standardIdentifier" : "chebi:36144",
    "referenceType" : "ReferenceMolecule",
    "parents" : [ 9707308 ],
    "children" : [ ]
  }, {
    "dbId" : 9707685,
    "stId" : "R-ALL-9707685",
    "displayName" : "FeHM [nuclear envelope]",
    "schemaClass" : "SimpleEntity",
    "speciesId" : 0,
    "identifier" : "36144",
    "standardIdentifier" : "chebi:36144",
    "referenceType" : "ReferenceMolecule",
    "parents" : [ 9707552 ],
    "children" : [ ]
  }, {
    "dbId" : 10320943,
    "stId" : "R-CFA-9707672",
    "displayName" : "ferrohemoglobin [extracellular region]",
    "schemaClass" : "Complex",
    "speciesId" : 49646,
    "diagramIds" : [ 36987 ],
    "parents" : [ 10320945 ],
    "children" : [ 10278383, 10278381 ]
  }, {
    "dbId" : 10329641,
    "stId" : "R-CFA-189445",
    "displayName" : "Metabolism of porphyrins",
    "schemaClass" : "Pathway",
    "speciesId" : 49646,
    "diagramIds" : [ 37037 ]
  }, {
    "dbId" : 9707552,
    "stId" : "R-ALL-9707552",
    "displayName" : "Hemes [nuclear envelope]",
    "schemaClass" : "CandidateSet",
    "speciesId" : 0,
    "parents" : [ 10320988 ],
    "children" : [ 9707665, 9707685 ]
  }, {
    "dbId" : 9707308,
    "stId" : "R-ALL-9707308",
    "displayName" : "Hemes [cytosol]",
    "schemaClass" : "CandidateSet",
    "speciesId" : 0,
    "diagramIds" : [ 37003 ],
    "parents" : [ 10321053 ],
    "children" : [ 917795, 71185 ]
  }, {
    "dbId" : 171066,
    "stId" : "R-ALL-171066",
    "displayName" : "PL [extracellular region]",
    "schemaClass" : "SimpleEntity",
    "speciesId" : 0,
    "identifier" : "16247",
    "standardIdentifier" : "chebi:16247",
    "referenceType" : "ReferenceMolecule",
    "parents" : [ 10320970, 10239116, 10240052, 10247996, 10320972, 10320974 ],
    "children" : [ ]
  }, {
    "dbId" : 10240037,
    "stId" : "R-CFA-174720",
    "displayName" : "APOA1 [extracellular region]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 49646,
    "identifier" : "A0A8I3MSG4",
    "standardIdentifier" : "uniprot:A0A8I3MSG4",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "APOA1" ],
    "parents" : [ 10320974, 10320972, 10247996, 10240052 ],
    "children" : [ ]
  }, {
    "dbId" : 9707310,
    "stId" : "R-ALL-9707310",
    "displayName" : "Hemes [extracellular region]",
    "schemaClass" : "CandidateSet",
    "speciesId" : 0,
    "diagramIds" : [ 36980 ],
    "parents" : [ 10320982, 10320950 ],
    "children" : [ 917877, 917955 ]
  }, {
    "dbId" : 10320988,
    "stId" : "R-CFA-9707603",
    "displayName" : "PGRMC2:Hemes [nuclear envelope]",
    "schemaClass" : "Complex",
    "speciesId" : 49646,
    "diagramIds" : [ 37007 ],
    "parents" : [ ],
    "children" : [ 10320986, 9707552 ]
  }, {
    "dbId" : 10320990,
    "stId" : "R-CFA-9707859",
    "displayName" : "PGRMC2 [nucleoplasm]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 49646,
    "diagramIds" : [ 37018 ],
    "identifier" : "A0A8I3Q6P2",
    "standardIdentifier" : "uniprot:A0A8I3Q6P2",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "PGRMC2" ],
    "parents" : [ 10320992 ],
    "children" : [ ]
  }, {
    "dbId" : 171076,
    "stId" : "R-ALL-171076",
    "displayName" : "CHEST [extracellular region]",
    "schemaClass" : "SimpleEntity",
    "speciesId" : 0,
    "identifier" : "17002",
    "standardIdentifier" : "chebi:17002",
    "referenceType" : "ReferenceMolecule",
    "parents" : [ 10239116, 10240052, 10320974, 10320970 ],
    "children" : [ ]
  }, {
    "dbId" : 10320986,
    "stId" : "R-CFA-9707674",
    "displayName" : "PGRMC2 [nuclear envelope]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 49646,
    "diagramIds" : [ 37006 ],
    "identifier" : "A0A8I3Q6P2",
    "standardIdentifier" : "uniprot:A0A8I3Q6P2",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "PGRMC2" ],
    "parents" : [ 10320988 ],
    "children" : [ ]
  }, {
    "dbId" : 10320980,
    "stId" : "R-CFA-9707658",
    "displayName" : "LY96 [extracellular region]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 49646,
    "diagramIds" : [ 36979 ],
    "identifier" : "A0A8I3PYX5",
    "standardIdentifier" : "uniprot:A0A8I3PYX5",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "LY96" ],
    "parents" : [ 10320982 ],
    "children" : [ ]
  }, {
    "dbId" : 10320982,
    "stId" : "R-CFA-9707530",
    "displayName" : "Hemes:LY96 [extracellular region]",
    "schemaClass" : "Complex",
    "speciesId" : 49646,
    "diagramIds" : [ 36981 ],
    "parents" : [ 10320996 ],
    "children" : [ 9707310, 10320980 ]
  }, {
    "dbId" : 917955,
    "stId" : "R-ALL-917955",
    "displayName" : "FeHM [extracellular region]",
    "schemaClass" : "SimpleEntity",
    "speciesId" : 0,
    "diagramIds" : [ 36993 ],
    "identifier" : "36144",
    "standardIdentifier" : "chebi:36144",
    "referenceType" : "ReferenceMolecule",
    "parents" : [ 10277624, 10277628, 9707310 ],
    "children" : [ ]
  }, {
    "dbId" : 10320976,
    "stId" : "R-CFA-9707636",
    "displayName" : "oxidized LDL,HDL [extracellular region]",
    "schemaClass" : "CandidateSet",
    "speciesId" : 49646,
    "diagramIds" : [ 36995 ],
    "parents" : [ ],
    "children" : [ 10320970, 10320974, 10320972 ]
  }, {
    "dbId" : 10320972,
    "stId" : "R-CFA-9707686",
    "displayName" : "oxidized discoidal HDL [extracellular region]",
    "schemaClass" : "Complex",
    "speciesId" : 49646,
    "parents" : [ 10320976 ],
    "children" : [ 171149, 10240037, 171066, 2186967 ]
  }, {
    "dbId" : 10320974,
    "stId" : "R-CFA-9707670",
    "displayName" : "oxidized spherical HDL [extracellular region]",
    "schemaClass" : "Complex",
    "speciesId" : 49646,
    "parents" : [ 10320976 ],
    "children" : [ 171149, 10240037, 171066, 2186967, 171076, 171126 ]
  }, {
    "dbId" : 10320968,
    "stId" : "R-CFA-9707486",
    "displayName" : "LDL,HDL [extracellular region]",
    "schemaClass" : "CandidateSet",
    "speciesId" : 49646,
    "diagramIds" : [ 36994 ],
    "parents" : [ ],
    "children" : [ 10239116, 10240052, 10247996 ]
  }, {
    "dbId" : 10265162,
    "stId" : "R-CFA-1008242",
    "displayName" : "MAFK [nucleoplasm]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 49646,
    "diagramIds" : [ 37010 ],
    "identifier" : "A0A8I3N8Q7",
    "standardIdentifier" : "uniprot:A0A8I3N8Q7",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "MAFK" ],
    "parents" : [ 10320962 ],
    "children" : [ ]
  }, {
    "dbId" : 10320970,
    "stId" : "R-CFA-9707539",
    "displayName" : "oxidized LDL [extracellular region]",
    "schemaClass" : "Complex",
    "speciesId" : 49646,
    "parents" : [ 10320976 ],
    "children" : [ 171149, 171066, 2186967, 171076, 10239114, 171126 ]
  }, {
    "dbId" : 10237893,
    "stId" : "R-CFA-166045",
    "displayName" : "TLR4 [plasma membrane]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 49646,
    "diagramIds" : [ 36983 ],
    "identifier" : "A0A8I3RZ33",
    "standardIdentifier" : "uniprot:A0A8I3RZ33",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "TLR4" ],
    "parents" : [ 10320996 ],
    "children" : [ ]
  }, {
    "dbId" : 10320964,
    "stId" : "R-CFA-9707680",
    "displayName" : "BACH1:Hemes [nucleoplasm]",
    "schemaClass" : "Complex",
    "speciesId" : 49646,
    "diagramIds" : [ 37014 ],
    "parents" : [ 10321049 ],
    "children" : [ 10320960, 9707575 ]
  }, {
    "dbId" : 10320960,
    "stId" : "R-CFA-9707688",
    "displayName" : "BACH1 [nucleoplasm]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 49646,
    "diagramIds" : [ 37009 ],
    "identifier" : "A0A8I3PAQ6",
    "standardIdentifier" : "uniprot:A0A8I3PAQ6",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "BACH1" ],
    "parents" : [ 10320964, 10320962 ],
    "children" : [ ]
  }, {
    "dbId" : 10320962,
    "stId" : "R-CFA-9707629",
    "displayName" : "BACH1:MAFK [nucleoplasm]",
    "schemaClass" : "Complex",
    "speciesId" : 49646,
    "diagramIds" : [ 37011 ],
    "parents" : [ ],
    "children" : [ 10320960, 10265162 ]
  }, {
    "dbId" : 10277628,
    "stId" : "R-CFA-2168846",
    "displayName" : "Hemoglobin beta:ferriheme b [extracellular region]",
    "schemaClass" : "Complex",
    "speciesId" : 49646,
    "parents" : [ 10277630 ],
    "children" : [ 917955, 10277626 ]
  }, {
    "dbId" : 10277630,
    "stId" : "R-CFA-2168866",
    "displayName" : "MetHb [extracellular region]",
    "schemaClass" : "Complex",
    "speciesId" : 49646,
    "diagramIds" : [ 36990 ],
    "parents" : [ ],
    "children" : [ 10277624, 10277628 ]
  }, {
    "dbId" : 10277624,
    "stId" : "R-CFA-2168874",
    "displayName" : "Hemoglobin alpha:ferriheme b [extracellular region]",
    "schemaClass" : "Complex",
    "speciesId" : 49646,
    "parents" : [ 10277630 ],
    "children" : [ 917955, 10277622 ]
  }, {
    "dbId" : 10277626,
    "stId" : "R-CFA-2168872",
    "displayName" : "GLNA2 [extracellular region]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 49646,
    "identifier" : "A0A1K0GGH0",
    "standardIdentifier" : "uniprot:A0A1K0GGH0",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "GLNA2" ],
    "parents" : [ 10320954, 10277628, 10278383 ],
    "children" : [ ]
  }, {
    "dbId" : 10294133,
    "stId" : "R-CFA-1472858",
    "displayName" : "CLEC1B [plasma membrane]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 49646,
    "identifier" : "A0A8I3PY16",
    "standardIdentifier" : "uniprot:A0A8I3PY16",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "CLEC1B" ],
    "parents" : [ 10294135 ],
    "children" : [ ]
  }, {
    "dbId" : 10277622,
    "stId" : "R-CFA-2168862",
    "displayName" : "HBQ1 [extracellular region]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 49646,
    "identifier" : "A0A8I3MCD6",
    "standardIdentifier" : "uniprot:A0A8I3MCD6",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "HBQ1" ],
    "parents" : [ 10320954, 10277624, 10278381 ],
    "children" : [ ]
  }, {
    "dbId" : 10294135,
    "stId" : "R-CFA-5684807",
    "displayName" : "CLEC1B dimer [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 49646,
    "diagramIds" : [ 37000 ],
    "parents" : [ 10320950 ],
    "children" : [ 10294133 ]
  }, {
    "dbId" : 9707647,
    "stId" : "R-ALL-9707647",
    "displayName" : "hydroxide [extracellular region]",
    "schemaClass" : "SimpleEntity",
    "speciesId" : 0,
    "diagramIds" : [ 36989 ],
    "identifier" : "16234",
    "standardIdentifier" : "chebi:16234",
    "referenceType" : "ReferenceMolecule",
    "parents" : [ ],
    "children" : [ ]
  }, {
    "dbId" : 10278381,
    "stId" : "R-CFA-2168850",
    "displayName" : "Hemoglobin alpha:ferroheme b [extracellular region]",
    "schemaClass" : "Complex",
    "speciesId" : 49646,
    "parents" : [ 10320943 ],
    "children" : [ 917877, 10277622 ]
  }, {
    "dbId" : 10278383,
    "stId" : "R-CFA-2168863",
    "displayName" : "Hemoglobin beta:ferroheme b [extracellular region]",
    "schemaClass" : "Complex",
    "speciesId" : 49646,
    "parents" : [ 10320943 ],
    "children" : [ 917877, 10277626 ]
  }, {
    "dbId" : 171126,
    "stId" : "R-ALL-171126",
    "displayName" : "TAGs [extracellular region]",
    "schemaClass" : "SimpleEntity",
    "speciesId" : 0,
    "identifier" : "17855",
    "standardIdentifier" : "chebi:17855",
    "referenceType" : "ReferenceMolecule",
    "parents" : [ 10239116, 10240052, 10320974, 10320970 ],
    "children" : [ ]
  }, {
    "dbId" : 10238697,
    "stId" : "R-CFA-165529",
    "displayName" : "XPO1 [nucleoplasm]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 49646,
    "diagramIds" : [ 37020 ],
    "identifier" : "A0A8I3NNH1",
    "standardIdentifier" : "uniprot:A0A8I3NNH1",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "XPO1" ],
    "parents" : [ 10321049 ],
    "children" : [ ]
  }, {
    "dbId" : 2186967,
    "stId" : "R-ALL-2186967",
    "displayName" : "oxidized phospholipids [extracellular region]",
    "schemaClass" : "SimpleEntity",
    "speciesId" : 0,
    "identifier" : "60156",
    "standardIdentifier" : "chebi:60156",
    "referenceType" : "ReferenceMolecule",
    "parents" : [ 10320970, 10320974, 10320972 ],
    "children" : [ ]
  }, {
    "dbId" : 10320996,
    "stId" : "R-CFA-9707678",
    "displayName" : "TLR4:Hemes:LY96 [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 49646,
    "diagramIds" : [ 36984 ],
    "parents" : [ ],
    "children" : [ 10320982, 10237893 ]
  }, {
    "dbId" : 917877,
    "stId" : "R-ALL-917877",
    "displayName" : "heme [extracellular region]",
    "schemaClass" : "SimpleEntity",
    "speciesId" : 0,
    "diagramIds" : [ 36996 ],
    "identifier" : "60344",
    "standardIdentifier" : "chebi:60344",
    "referenceType" : "ReferenceMolecule",
    "parents" : [ 10278383, 10278381, 9707310 ],
    "children" : [ ]
  }, {
    "dbId" : 9707624,
    "stId" : "R-ALL-9707624",
    "displayName" : "hydroxyl [extracellular region]",
    "schemaClass" : "SimpleEntity",
    "speciesId" : 0,
    "diagramIds" : [ 36988 ],
    "identifier" : "29191",
    "standardIdentifier" : "chebi:29191",
    "referenceType" : "ReferenceMolecule",
    "parents" : [ ],
    "children" : [ ]
  }, {
    "dbId" : 10320992,
    "stId" : "R-CFA-9707849",
    "displayName" : "PGRMC2:Hemes [nucleoplasm]",
    "schemaClass" : "Complex",
    "speciesId" : 49646,
    "diagramIds" : [ 37016 ],
    "parents" : [ ],
    "children" : [ 10320990, 9707575 ]
  } ],
  "edges" : [ {
    "dbId" : 10262140,
    "stId" : "R-CFA-917870",
    "displayName" : "SLC46A1 transports hemes from extracellular region to cytosol",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "inputs" : [ 9707310 ],
    "outputs" : [ 9707308 ],
    "catalysts" : [ 10244361 ],
    "efs" : [ ],
    "diagramIds" : [ 37002 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10320956,
    "stId" : "R-CFA-9707516",
    "displayName" : "FeHM dissociates from MetHb",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "preceding" : [ 10320947 ],
    "following" : [ 10320978 ],
    "inputs" : [ 10277630 ],
    "outputs" : [ 917955, 10320954 ],
    "efs" : [ ],
    "diagramIds" : [ 36997 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10320984,
    "stId" : "R-CFA-9707594",
    "displayName" : "Hemes bind LY96",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "following" : [ 10320998 ],
    "inputs" : [ 9707310, 10320980 ],
    "outputs" : [ 10320982 ],
    "efs" : [ ],
    "diagramIds" : [ 36978 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10320952,
    "stId" : "R-CFA-9707505",
    "displayName" : "Hemes bind to CLEC1B dimer",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "inputs" : [ 9707310, 10294135 ],
    "outputs" : [ 10320950 ],
    "efs" : [ ],
    "diagramIds" : [ 36999 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10320947,
    "stId" : "R-CFA-9707504",
    "displayName" : "H2O2 oxidises ferrohemoglobin to MetHb",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "following" : [ 10320956 ],
    "inputs" : [ 351629, 10320943 ],
    "outputs" : [ 9707624, 9707647, 10277630 ],
    "efs" : [ ],
    "inhibitors" : [ 10320945 ],
    "diagramIds" : [ 36985 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10320978,
    "stId" : "R-CFA-9707586",
    "displayName" : "FeHM oxidises LDL,HDL",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "preceding" : [ 10320956 ],
    "inputs" : [ 917955, 10320968 ],
    "outputs" : [ 10320976, 917877 ],
    "efs" : [ ],
    "diagramIds" : [ 36992 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10321004,
    "stId" : "R-CFA-9707856",
    "displayName" : "PGRMC2:Hemes dissociates",
    "schemaClass" : "BlackBoxEvent",
    "speciesId" : 0,
    "preceding" : [ 10320994 ],
    "inputs" : [ 10320992 ],
    "outputs" : [ 9707575, 10320990 ],
    "efs" : [ ],
    "diagramIds" : [ 37017 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10321000,
    "stId" : "R-CFA-9707683",
    "displayName" : "PGRMC2 binds Hemes",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "following" : [ 10320994 ],
    "inputs" : [ 9707308, 10320986 ],
    "outputs" : [ 10320988 ],
    "efs" : [ ],
    "diagramIds" : [ 37005 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10321002,
    "stId" : "R-CFA-9707690",
    "displayName" : "BACH1 binds MAFK",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "following" : [ 10320966 ],
    "inputs" : [ 10320960, 10265162 ],
    "outputs" : [ 10320962 ],
    "efs" : [ ],
    "diagramIds" : [ 37008 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10320998,
    "stId" : "R-CFA-9707659",
    "displayName" : "Hemes:LY96 activates TLR4",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "preceding" : [ 10320984 ],
    "inputs" : [ 10320982, 10237893 ],
    "outputs" : [ 10320996 ],
    "efs" : [ ],
    "diagramIds" : [ 36982 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10320966,
    "stId" : "R-CFA-9707523",
    "displayName" : "Hemes bind to BACH1:MAFK",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "preceding" : [ 10320994, 10321002 ],
    "following" : [ 10321059 ],
    "inputs" : [ 10320962, 9707575 ],
    "outputs" : [ 10320964, 10265162 ],
    "efs" : [ ],
    "diagramIds" : [ 37012 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10321057,
    "stId" : "R-CFA-9708423",
    "displayName" : "XPO1:BACH1:Hemes are transported out of the nucleus",
    "schemaClass" : "BlackBoxEvent",
    "speciesId" : 0,
    "preceding" : [ 10321059 ],
    "inputs" : [ 10321049 ],
    "outputs" : [ 10321055 ],
    "efs" : [ ],
    "diagramIds" : [ 37022 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10321059,
    "stId" : "R-CFA-9708430",
    "displayName" : "XPO1 (CRM1) binds to BACH1:Hemes",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "preceding" : [ 10320966 ],
    "following" : [ 10321057 ],
    "inputs" : [ 10320964, 10238697 ],
    "outputs" : [ 10321049 ],
    "efs" : [ ],
    "diagramIds" : [ 37019 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10320994,
    "stId" : "R-CFA-9707606",
    "displayName" : "PGRMC2:Hemes translocate to the nucleus",
    "schemaClass" : "BlackBoxEvent",
    "speciesId" : 0,
    "preceding" : [ 10321000 ],
    "following" : [ 10321004, 10320966 ],
    "inputs" : [ 10320988 ],
    "outputs" : [ 10320992 ],
    "efs" : [ ],
    "diagramIds" : [ 37015 ],
    "entityFunctionalStatus" : [ ]
  } ]
}