{
  "dbId" : 10331219,
  "stableId" : "R-CFA-9012999",
  "displayName" : "RHO GTPase cycle",
  "nodes" : [ {
    "id" : 75776,
    "reactomeId" : 10316934,
    "displayName" : "RAC2 GEFs",
    "schemaClass" : "CandidateSet",
    "renderableClass" : "EntitySet",
    "position" : {
      "x" : 2677,
      "y" : 173
    },
    "minX" : 2641,
    "maxX" : 2714,
    "minY" : 79,
    "maxY" : 184,
    "prop" : {
      "x" : 2641,
      "y" : 162,
      "width" : 73,
      "height" : 22
    },
    "textPosition" : {
      "x" : 2655,
      "y" : 156
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 204
    },
    "fgColor" : {
      "r" : 0,
      "g" : 0,
      "b" : 0
    },
    "connectors" : [ {
      "edgeId" : 75771,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 2677,
          "y" : 156
        },
        "to" : {
          "x" : 2677,
          "y" : 87
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 2677,
          "y" : 83
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 2677,
          "y" : 83
        }
      }
    } ]
  }, {
    "id" : 75779,
    "reactomeId" : 29372,
    "displayName" : "Pi",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 2552,
      "y" : 256
    },
    "minX" : 2537,
    "maxX" : 2588,
    "minY" : 216,
    "maxY" : 268,
    "prop" : {
      "x" : 2537,
      "y" : 244,
      "width" : 31,
      "height" : 24
    },
    "textPosition" : {
      "x" : 2543,
      "y" : 245
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 2563,
          "y" : 249
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 2563,
          "y" : 249
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 75777,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 2562,
          "y" : 241
        },
        "to" : {
          "x" : 2588,
          "y" : 216
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 2564,
          "y" : 233
        },
        "b" : {
          "x" : 2562,
          "y" : 241
        },
        "c" : {
          "x" : 2570,
          "y" : 239
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 2570,
          "y" : 239
        }
      }
    } ]
  }, {
    "id" : 75778,
    "reactomeId" : 29356,
    "displayName" : "H2O",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 2770,
      "y" : 262
    },
    "minX" : 2751,
    "maxX" : 2791,
    "minY" : 202,
    "maxY" : 276,
    "prop" : {
      "x" : 2751,
      "y" : 249,
      "width" : 39,
      "height" : 27
    },
    "textPosition" : {
      "x" : 2753,
      "y" : 252
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 2785,
          "y" : 254
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 2785,
          "y" : 254
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 75777,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 2770,
          "y" : 246
        },
        "to" : {
          "x" : 2773,
          "y" : 202
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ],
    "trivial" : true
  }, {
    "id" : 75780,
    "reactomeId" : 10316929,
    "displayName" : "RAC2 GAPs",
    "schemaClass" : "CandidateSet",
    "renderableClass" : "EntitySet",
    "position" : {
      "x" : 2685,
      "y" : 307
    },
    "minX" : 2648,
    "maxX" : 2723,
    "minY" : 229,
    "maxY" : 318,
    "prop" : {
      "x" : 2648,
      "y" : 296,
      "width" : 75,
      "height" : 22
    },
    "textPosition" : {
      "x" : 2663,
      "y" : 290
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 204
    },
    "fgColor" : {
      "r" : 0,
      "g" : 0,
      "b" : 0
    },
    "connectors" : [ {
      "edgeId" : 75777,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 2685,
          "y" : 290
        },
        "to" : {
          "x" : 2686,
          "y" : 237
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 2686,
          "y" : 233
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 2686,
          "y" : 233
        }
      }
    } ]
  }, {
    "id" : 75783,
    "reactomeId" : 10316917,
    "displayName" : "ARHGDIA:RAC2:GDP",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 2527,
      "y" : 197
    },
    "minX" : 2489,
    "maxX" : 2571,
    "minY" : 173,
    "maxY" : 216,
    "prop" : {
      "x" : 2489,
      "y" : 179,
      "width" : 76,
      "height" : 37
    },
    "textPosition" : {
      "x" : 2492,
      "y" : 181
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 2565,
          "y" : 179
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 2565,
          "y" : 179
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 75781,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 75782,
    "reactomeId" : 10242465,
    "displayName" : "ARHGDIA",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 2476,
      "y" : 120
    },
    "minX" : 2445,
    "maxX" : 2543,
    "minY" : 103,
    "maxY" : 131,
    "prop" : {
      "x" : 2445,
      "y" : 109,
      "width" : 63,
      "height" : 22
    },
    "textPosition" : {
      "x" : 2445,
      "y" : 109
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 2508,
          "y" : 109
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 2508,
          "y" : 109
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 75781,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 2511,
          "y" : 116
        },
        "to" : {
          "x" : 2543,
          "y" : 113
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 75785,
    "reactomeId" : 10316923,
    "displayName" : "RAC2 plasma membrane effectors",
    "schemaClass" : "CandidateSet",
    "renderableClass" : "EntitySet",
    "position" : {
      "x" : 2895,
      "y" : 181
    },
    "minX" : 2847,
    "maxX" : 2943,
    "minY" : 128,
    "maxY" : 203,
    "prop" : {
      "x" : 2847,
      "y" : 159,
      "width" : 96,
      "height" : 44
    },
    "textPosition" : {
      "x" : 2848,
      "y" : 157
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 204
    },
    "fgColor" : {
      "r" : 0,
      "g" : 0,
      "b" : 0
    },
    "connectors" : [ {
      "edgeId" : 75784,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 2906,
          "y" : 153
        },
        "to" : {
          "x" : 2922,
          "y" : 128
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 75786,
    "reactomeId" : 10316925,
    "displayName" : "RAC2:GTP:RAC2 cytosolic effectors",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 3026,
      "y" : 67
    },
    "minX" : 2971,
    "maxX" : 3088,
    "minY" : 43,
    "maxY" : 85,
    "prop" : {
      "x" : 2971,
      "y" : 49,
      "width" : 111,
      "height" : 36
    },
    "textPosition" : {
      "x" : 2972,
      "y" : 36
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 3082,
          "y" : 49
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 3082,
          "y" : 49
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 75784,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 75788,
    "reactomeId" : 10292546,
    "displayName" : "RAC2:GTP",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 2759,
      "y" : 431
    },
    "minX" : 2725,
    "maxX" : 2846,
    "minY" : 414,
    "maxY" : 457,
    "prop" : {
      "x" : 2725,
      "y" : 420,
      "width" : 69,
      "height" : 22
    },
    "textPosition" : {
      "x" : 2725,
      "y" : 421
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 2794,
          "y" : 420
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 2794,
          "y" : 420
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 75787,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 75789,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 2797,
          "y" : 441
        },
        "to" : {
          "x" : 2846,
          "y" : 457
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 75791,
    "reactomeId" : 10292548,
    "displayName" : "NOX2 complex:RAC2:GTP",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 2908,
      "y" : 521
    },
    "minX" : 2843,
    "maxX" : 2979,
    "minY" : 497,
    "maxY" : 539,
    "prop" : {
      "x" : 2843,
      "y" : 503,
      "width" : 130,
      "height" : 36
    },
    "textPosition" : {
      "x" : 2858,
      "y" : 504
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 2973,
          "y" : 503
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 2973,
          "y" : 503
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 75789,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 75790,
    "reactomeId" : 10266248,
    "displayName" : "NOX2 complex",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 2871,
      "y" : 406
    },
    "minX" : 2825,
    "maxX" : 2924,
    "minY" : 377,
    "maxY" : 457,
    "prop" : {
      "x" : 2825,
      "y" : 383,
      "width" : 93,
      "height" : 47
    },
    "textPosition" : {
      "x" : 2842,
      "y" : 389
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 2918,
          "y" : 383
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 2918,
          "y" : 383
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 75789,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 2859,
          "y" : 436
        },
        "to" : {
          "x" : 2846,
          "y" : 457
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 75793,
    "reactomeId" : 10316943,
    "displayName" : "RHOG:GDP",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 53,
      "y" : 387
    },
    "minX" : 17,
    "maxX" : 231,
    "minY" : 339,
    "maxY" : 432,
    "prop" : {
      "x" : 17,
      "y" : 376,
      "width" : 73,
      "height" : 22
    },
    "textPosition" : {
      "x" : 17,
      "y" : 377
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 90,
          "y" : 376
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 90,
          "y" : 376
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 75792,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 51,
          "y" : 401
        },
        "to" : {
          "x" : 48,
          "y" : 432
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 75798,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 93,
          "y" : 389
        },
        "to" : {
          "x" : 231,
          "y" : 400
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 100,
          "y" : 386
        },
        "b" : {
          "x" : 93,
          "y" : 389
        },
        "c" : {
          "x" : 100,
          "y" : 394
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 100,
          "y" : 394
        }
      }
    }, {
      "edgeId" : 75801,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 61,
          "y" : 373
        },
        "to" : {
          "x" : 91,
          "y" : 339
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 75795,
    "reactomeId" : 10234771,
    "displayName" : "RHOG:GTP",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 45,
      "y" : 564
    },
    "minX" : 9,
    "maxX" : 215,
    "minY" : 518,
    "maxY" : 612,
    "prop" : {
      "x" : 9,
      "y" : 553,
      "width" : 72,
      "height" : 22
    },
    "textPosition" : {
      "x" : 9,
      "y" : 554
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 81,
          "y" : 553
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 81,
          "y" : 553
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 75792,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 46,
          "y" : 550
        },
        "to" : {
          "x" : 51,
          "y" : 518
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 43,
          "y" : 543
        },
        "b" : {
          "x" : 46,
          "y" : 550
        },
        "c" : {
          "x" : 51,
          "y" : 544
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 51,
          "y" : 544
        }
      }
    }, {
      "edgeId" : 75798,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 84,
          "y" : 562
        },
        "to" : {
          "x" : 215,
          "y" : 556
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 75804,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 58,
          "y" : 578
        },
        "to" : {
          "x" : 105,
          "y" : 612
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 75807,
      "type" : "INPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 75794,
    "reactomeId" : 29438,
    "displayName" : "GTP",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 121,
      "y" : 425
    },
    "minX" : 48,
    "maxX" : 143,
    "minY" : 409,
    "maxY" : 440,
    "prop" : {
      "x" : 101,
      "y" : 410,
      "width" : 41,
      "height" : 30
    },
    "textPosition" : {
      "x" : 105,
      "y" : 414
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 137,
          "y" : 415
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 137,
          "y" : 415
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 75792,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 98,
          "y" : 426
        },
        "to" : {
          "x" : 48,
          "y" : 432
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 75797,
    "reactomeId" : 10316945,
    "displayName" : "RHOG GEFs",
    "schemaClass" : "CandidateSet",
    "renderableClass" : "EntitySet",
    "position" : {
      "x" : 157,
      "y" : 474
    },
    "minX" : 57,
    "maxX" : 195,
    "minY" : 463,
    "maxY" : 485,
    "prop" : {
      "x" : 119,
      "y" : 463,
      "width" : 76,
      "height" : 22
    },
    "textPosition" : {
      "x" : 133,
      "y" : 457
    },
    "connectors" : [ {
      "edgeId" : 75792,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 113,
          "y" : 476
        },
        "to" : {
          "x" : 65,
          "y" : 480
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 61,
          "y" : 480
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 61,
          "y" : 480
        }
      }
    } ]
  }, {
    "id" : 75796,
    "reactomeId" : 29420,
    "displayName" : "GDP",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 117,
      "y" : 529
    },
    "minX" : 51,
    "maxX" : 139,
    "minY" : 513,
    "maxY" : 544,
    "prop" : {
      "x" : 96,
      "y" : 514,
      "width" : 42,
      "height" : 30
    },
    "textPosition" : {
      "x" : 100,
      "y" : 518
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 133,
          "y" : 519
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 133,
          "y" : 519
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 75792,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 93,
          "y" : 525
        },
        "to" : {
          "x" : 51,
          "y" : 518
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 86,
          "y" : 528
        },
        "b" : {
          "x" : 93,
          "y" : 525
        },
        "c" : {
          "x" : 87,
          "y" : 520
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 87,
          "y" : 520
        }
      }
    } ]
  }, {
    "id" : 75799,
    "reactomeId" : 29356,
    "displayName" : "H2O",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 277,
      "y" : 594
    },
    "minX" : 215,
    "maxX" : 300,
    "minY" : 556,
    "maxY" : 609,
    "prop" : {
      "x" : 256,
      "y" : 579,
      "width" : 43,
      "height" : 30
    },
    "textPosition" : {
      "x" : 260,
      "y" : 583
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 294,
          "y" : 584
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 294,
          "y" : 584
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 75798,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 253,
          "y" : 580
        },
        "to" : {
          "x" : 215,
          "y" : 556
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ],
    "trivial" : true
  }, {
    "id" : 75800,
    "reactomeId" : 10316950,
    "displayName" : "RHOG GAPs",
    "schemaClass" : "CandidateSet",
    "renderableClass" : "EntitySet",
    "position" : {
      "x" : 320,
      "y" : 466
    },
    "minX" : 226,
    "maxX" : 359,
    "minY" : 455,
    "maxY" : 478,
    "prop" : {
      "x" : 281,
      "y" : 455,
      "width" : 78,
      "height" : 22
    },
    "textPosition" : {
      "x" : 296,
      "y" : 449
    },
    "connectors" : [ {
      "edgeId" : 75798,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 275,
          "y" : 469
        },
        "to" : {
          "x" : 234,
          "y" : 473
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 230,
          "y" : 474
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 230,
          "y" : 474
        }
      }
    } ]
  }, {
    "id" : 75803,
    "reactomeId" : 10316977,
    "displayName" : "RHOG GDIs:RHOG:GDP",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 188,
      "y" : 338
    },
    "minX" : 144,
    "maxX" : 239,
    "minY" : 314,
    "maxY" : 357,
    "prop" : {
      "x" : 144,
      "y" : 320,
      "width" : 89,
      "height" : 37
    },
    "textPosition" : {
      "x" : 149,
      "y" : 322
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 233,
          "y" : 320
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 233,
          "y" : 320
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 75801,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 75802,
    "reactomeId" : 10316973,
    "displayName" : "ARHGDIA,ARHGDIB,ARHGDIG",
    "schemaClass" : "DefinedSet",
    "renderableClass" : "EntitySet",
    "position" : {
      "x" : 106,
      "y" : 279
    },
    "minX" : 69,
    "maxX" : 144,
    "minY" : 256,
    "maxY" : 339,
    "prop" : {
      "x" : 69,
      "y" : 256,
      "width" : 75,
      "height" : 47
    },
    "textPosition" : {
      "x" : 73,
      "y" : 255
    },
    "connectors" : [ {
      "edgeId" : 75801,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 100,
          "y" : 309
        },
        "to" : {
          "x" : 91,
          "y" : 339
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 75805,
    "reactomeId" : 10316963,
    "displayName" : "RHOG plasma membrane effectors",
    "schemaClass" : "CandidateSet",
    "renderableClass" : "EntitySet",
    "position" : {
      "x" : 196,
      "y" : 649
    },
    "minX" : 105,
    "maxX" : 259,
    "minY" : 612,
    "maxY" : 667,
    "prop" : {
      "x" : 133,
      "y" : 631,
      "width" : 126,
      "height" : 36
    },
    "textPosition" : {
      "x" : 148,
      "y" : 625
    },
    "connectors" : [ {
      "edgeId" : 75804,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 151,
          "y" : 625
        },
        "to" : {
          "x" : 105,
          "y" : 612
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 75806,
    "reactomeId" : 10316965,
    "displayName" : "RHOG:GTP:RHOG plasma membrane effectors",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 61,
      "y" : 722
    },
    "minX" : 0,
    "maxX" : 128,
    "minY" : 691,
    "maxY" : 747,
    "prop" : {
      "x" : 0,
      "y" : 697,
      "width" : 122,
      "height" : 50
    },
    "textPosition" : {
      "x" : 4,
      "y" : 684
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 122,
          "y" : 697
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 122,
          "y" : 697
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 75804,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 75808,
    "reactomeId" : 10316969,
    "displayName" : "RHOG:GTP",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 621,
      "y" : 498
    },
    "minX" : 585,
    "maxX" : 709,
    "minY" : 481,
    "maxY" : 509,
    "prop" : {
      "x" : 585,
      "y" : 487,
      "width" : 72,
      "height" : 22
    },
    "textPosition" : {
      "x" : 585,
      "y" : 488
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 657,
          "y" : 487
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 657,
          "y" : 487
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 75807,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 75809,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 660,
          "y" : 500
        },
        "to" : {
          "x" : 709,
          "y" : 505
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 75811,
    "reactomeId" : 10316995,
    "displayName" : "RHOG:GTP:RHOG endoplasmic reticulum effectors",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 662,
      "y" : 398
    },
    "minX" : 569,
    "maxX" : 762,
    "minY" : 373,
    "maxY" : 418,
    "prop" : {
      "x" : 569,
      "y" : 379,
      "width" : 187,
      "height" : 39
    },
    "textPosition" : {
      "x" : 586,
      "y" : 369
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 756,
          "y" : 379
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 756,
          "y" : 379
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 75809,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 75810,
    "reactomeId" : 10316993,
    "displayName" : "RHOG endoplasmic reticulum effectors",
    "schemaClass" : "CandidateSet",
    "renderableClass" : "EntitySet",
    "position" : {
      "x" : 640,
      "y" : 556
    },
    "minX" : 578,
    "maxX" : 709,
    "minY" : 505,
    "maxY" : 574,
    "prop" : {
      "x" : 578,
      "y" : 538,
      "width" : 125,
      "height" : 36
    },
    "textPosition" : {
      "x" : 595,
      "y" : 525
    },
    "connectors" : [ {
      "edgeId" : 75809,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 664,
          "y" : 532
        },
        "to" : {
          "x" : 709,
          "y" : 505
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 75813,
    "reactomeId" : 10317193,
    "displayName" : "RHOBTB1",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 389,
      "y" : 1939
    },
    "minX" : 355,
    "maxX" : 457,
    "minY" : 1922,
    "maxY" : 1950,
    "prop" : {
      "x" : 355,
      "y" : 1928,
      "width" : 69,
      "height" : 22
    },
    "textPosition" : {
      "x" : 357,
      "y" : 1928
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 424,
          "y" : 1928
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 424,
          "y" : 1928
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 75812,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 427,
          "y" : 1941
        },
        "to" : {
          "x" : 457,
          "y" : 1943
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 75815,
    "reactomeId" : 10317195,
    "displayName" : "RHOBTB1:GTP",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 590,
      "y" : 1945
    },
    "minX" : 544,
    "maxX" : 664,
    "minY" : 1928,
    "maxY" : 1956,
    "prop" : {
      "x" : 544,
      "y" : 1934,
      "width" : 93,
      "height" : 22
    },
    "textPosition" : {
      "x" : 544,
      "y" : 1935
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 637,
          "y" : 1934
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 637,
          "y" : 1934
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 75812,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 75816,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 640,
          "y" : 1943
        },
        "to" : {
          "x" : 664,
          "y" : 1942
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 75814,
    "reactomeId" : 29438,
    "displayName" : "GTP",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 446,
      "y" : 1883
    },
    "minX" : 426,
    "maxX" : 467,
    "minY" : 1870,
    "maxY" : 1943,
    "prop" : {
      "x" : 426,
      "y" : 1871,
      "width" : 40,
      "height" : 25
    },
    "textPosition" : {
      "x" : 430,
      "y" : 1873
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 461,
          "y" : 1876
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 461,
          "y" : 1876
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 75812,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 448,
          "y" : 1899
        },
        "to" : {
          "x" : 457,
          "y" : 1943
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 75817,
    "reactomeId" : 10317217,
    "displayName" : "RHOBTB1 interacting proteins",
    "schemaClass" : "CandidateSet",
    "renderableClass" : "EntitySet",
    "position" : {
      "x" : 645,
      "y" : 1860
    },
    "minX" : 585,
    "maxX" : 706,
    "minY" : 1846,
    "maxY" : 1942,
    "prop" : {
      "x" : 585,
      "y" : 1846,
      "width" : 121,
      "height" : 29
    },
    "textPosition" : {
      "x" : 605,
      "y" : 1836
    },
    "connectors" : [ {
      "edgeId" : 75816,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 648,
          "y" : 1881
        },
        "to" : {
          "x" : 664,
          "y" : 1942
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 75818,
    "reactomeId" : 10317219,
    "displayName" : "RHOBTB1:GTP:RHOBTB1 interacting proteins",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 842,
      "y" : 1945
    },
    "minX" : 781,
    "maxX" : 909,
    "minY" : 1915,
    "maxY" : 1969,
    "prop" : {
      "x" : 781,
      "y" : 1921,
      "width" : 122,
      "height" : 48
    },
    "textPosition" : {
      "x" : 793,
      "y" : 1906
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 903,
          "y" : 1921
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 903,
          "y" : 1921
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 75816,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 75821,
    "reactomeId" : 29438,
    "displayName" : "GTP",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 446,
      "y" : 2229
    },
    "minX" : 425,
    "maxX" : 468,
    "minY" : 2195,
    "maxY" : 2242,
    "prop" : {
      "x" : 425,
      "y" : 2216,
      "width" : 42,
      "height" : 26
    },
    "textPosition" : {
      "x" : 430,
      "y" : 2218
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 462,
          "y" : 2221
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 462,
          "y" : 2221
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 75819,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 450,
          "y" : 2213
        },
        "to" : {
          "x" : 457,
          "y" : 2195
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 75820,
    "reactomeId" : 10317225,
    "displayName" : "RHOBTB2",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 381,
      "y" : 2189
    },
    "minX" : 345,
    "maxX" : 457,
    "minY" : 2172,
    "maxY" : 2200,
    "prop" : {
      "x" : 345,
      "y" : 2178,
      "width" : 72,
      "height" : 22
    },
    "textPosition" : {
      "x" : 348,
      "y" : 2178
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 417,
          "y" : 2178
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 417,
          "y" : 2178
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 75819,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 420,
          "y" : 2191
        },
        "to" : {
          "x" : 457,
          "y" : 2195
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 75823,
    "reactomeId" : 10317231,
    "displayName" : "HSP90:CDC37",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 514,
      "y" : 2265
    },
    "minX" : 468,
    "maxX" : 566,
    "minY" : 2202,
    "maxY" : 2276,
    "prop" : {
      "x" : 468,
      "y" : 2254,
      "width" : 92,
      "height" : 22
    },
    "textPosition" : {
      "x" : 487,
      "y" : 2241
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 560,
          "y" : 2254
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 560,
          "y" : 2254
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 75819,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 513,
          "y" : 2251
        },
        "to" : {
          "x" : 512,
          "y" : 2210
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 512,
          "y" : 2206
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 512,
          "y" : 2206
        }
      }
    } ]
  }, {
    "id" : 75822,
    "reactomeId" : 10317227,
    "displayName" : "RHOBTB2:GTP",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 607,
      "y" : 2189
    },
    "minX" : 560,
    "maxX" : 685,
    "minY" : 2170,
    "maxY" : 2202,
    "prop" : {
      "x" : 560,
      "y" : 2176,
      "width" : 94,
      "height" : 26
    },
    "textPosition" : {
      "x" : 560,
      "y" : 2181
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 654,
          "y" : 2176
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 654,
          "y" : 2176
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 75819,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 75824,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 657,
          "y" : 2189
        },
        "to" : {
          "x" : 685,
          "y" : 2190
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 75825,
    "reactomeId" : 10317250,
    "displayName" : "RHOBTB2 interacting proteins",
    "schemaClass" : "CandidateSet",
    "renderableClass" : "EntitySet",
    "position" : {
      "x" : 684,
      "y" : 2253
    },
    "minX" : 624,
    "maxX" : 744,
    "minY" : 2190,
    "maxY" : 2269,
    "prop" : {
      "x" : 624,
      "y" : 2238,
      "width" : 120,
      "height" : 31
    },
    "textPosition" : {
      "x" : 644,
      "y" : 2229
    },
    "connectors" : [ {
      "edgeId" : 75824,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 684,
          "y" : 2232
        },
        "to" : {
          "x" : 685,
          "y" : 2190
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 75826,
    "reactomeId" : 10317252,
    "displayName" : "RHOBTB2:GTP:RHOBTB2 interacting proteins",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 817,
      "y" : 2194
    },
    "minX" : 757,
    "maxX" : 884,
    "minY" : 2165,
    "maxY" : 2217,
    "prop" : {
      "x" : 757,
      "y" : 2171,
      "width" : 121,
      "height" : 46
    },
    "textPosition" : {
      "x" : 769,
      "y" : 2154
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 878,
          "y" : 2171
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 878,
          "y" : 2171
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 75824,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 75829,
    "reactomeId" : 29438,
    "displayName" : "GTP",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 562,
      "y" : 2335
    },
    "minX" : 542,
    "maxX" : 607,
    "minY" : 2319,
    "maxY" : 2396,
    "prop" : {
      "x" : 542,
      "y" : 2320,
      "width" : 41,
      "height" : 30
    },
    "textPosition" : {
      "x" : 546,
      "y" : 2324
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 578,
          "y" : 2325
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 578,
          "y" : 2325
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 75827,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 573,
          "y" : 2353
        },
        "to" : {
          "x" : 607,
          "y" : 2396
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 75828,
    "reactomeId" : 10317272,
    "displayName" : "RHOV:GDP",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 517,
      "y" : 2413
    },
    "minX" : 481,
    "maxX" : 607,
    "minY" : 2396,
    "maxY" : 2424,
    "prop" : {
      "x" : 481,
      "y" : 2402,
      "width" : 72,
      "height" : 22
    },
    "textPosition" : {
      "x" : 481,
      "y" : 2403
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 553,
          "y" : 2402
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 553,
          "y" : 2402
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 75827,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 556,
          "y" : 2406
        },
        "to" : {
          "x" : 607,
          "y" : 2396
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 75831,
    "reactomeId" : 29420,
    "displayName" : "GDP",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 718,
      "y" : 2347
    },
    "minX" : 678,
    "maxX" : 740,
    "minY" : 2331,
    "maxY" : 2397,
    "prop" : {
      "x" : 697,
      "y" : 2332,
      "width" : 42,
      "height" : 30
    },
    "textPosition" : {
      "x" : 701,
      "y" : 2336
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 734,
          "y" : 2337
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 734,
          "y" : 2337
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 75827,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 706,
          "y" : 2365
        },
        "to" : {
          "x" : 678,
          "y" : 2397
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 704,
          "y" : 2373
        },
        "b" : {
          "x" : 706,
          "y" : 2365
        },
        "c" : {
          "x" : 698,
          "y" : 2368
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 698,
          "y" : 2368
        }
      }
    } ]
  }, {
    "id" : 75830,
    "reactomeId" : 10317260,
    "displayName" : "RHOV:GTP",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 750,
      "y" : 2415
    },
    "minX" : 678,
    "maxX" : 801,
    "minY" : 2364,
    "maxY" : 2426,
    "prop" : {
      "x" : 715,
      "y" : 2404,
      "width" : 71,
      "height" : 22
    },
    "textPosition" : {
      "x" : 715,
      "y" : 2405
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 786,
          "y" : 2404
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 786,
          "y" : 2404
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 75827,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 712,
          "y" : 2406
        },
        "to" : {
          "x" : 678,
          "y" : 2397
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 704,
          "y" : 2408
        },
        "b" : {
          "x" : 712,
          "y" : 2406
        },
        "c" : {
          "x" : 706,
          "y" : 2400
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 706,
          "y" : 2400
        }
      }
    }, {
      "edgeId" : 75832,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 761,
          "y" : 2401
        },
        "to" : {
          "x" : 801,
          "y" : 2364
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 75833,
    "reactomeId" : 10317266,
    "displayName" : "RHOV effectors",
    "schemaClass" : "CandidateSet",
    "renderableClass" : "EntitySet",
    "position" : {
      "x" : 816,
      "y" : 2290
    },
    "minX" : 768,
    "maxX" : 865,
    "minY" : 2279,
    "maxY" : 2364,
    "prop" : {
      "x" : 768,
      "y" : 2279,
      "width" : 97,
      "height" : 22
    },
    "textPosition" : {
      "x" : 784,
      "y" : 2273
    },
    "connectors" : [ {
      "edgeId" : 75832,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 813,
          "y" : 2307
        },
        "to" : {
          "x" : 801,
          "y" : 2364
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 75834,
    "reactomeId" : 10317268,
    "displayName" : "RHOV:GTP:RHOV effectors",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 876,
      "y" : 2412
    },
    "minX" : 828,
    "maxX" : 930,
    "minY" : 2388,
    "maxY" : 2431,
    "prop" : {
      "x" : 828,
      "y" : 2394,
      "width" : 96,
      "height" : 37
    },
    "textPosition" : {
      "x" : 839,
      "y" : 2382
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 924,
          "y" : 2394
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 924,
          "y" : 2394
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 75832,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 75836,
    "reactomeId" : 10320329,
    "displayName" : "RAC1:GTP",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 980,
      "y" : 421
    },
    "minX" : 896,
    "maxX" : 1020,
    "minY" : 404,
    "maxY" : 432,
    "prop" : {
      "x" : 946,
      "y" : 410,
      "width" : 68,
      "height" : 22
    },
    "textPosition" : {
      "x" : 946,
      "y" : 411
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1014,
          "y" : 410
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1014,
          "y" : 410
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 75835,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 75837,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 943,
          "y" : 419
        },
        "to" : {
          "x" : 896,
          "y" : 417
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 75839,
    "reactomeId" : 10320335,
    "displayName" : "RAC1:GTP:RAC1 endoplasmic reticulum effectors",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 993,
      "y" : 473
    },
    "minX" : 935,
    "maxX" : 1057,
    "minY" : 442,
    "maxY" : 498,
    "prop" : {
      "x" : 935,
      "y" : 448,
      "width" : 116,
      "height" : 50
    },
    "textPosition" : {
      "x" : 939,
      "y" : 435
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1051,
          "y" : 448
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1051,
          "y" : 448
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 75837,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 75838,
    "reactomeId" : 10320333,
    "displayName" : "RAC1 endoplasmic reticulum effectors",
    "schemaClass" : "CandidateSet",
    "renderableClass" : "EntitySet",
    "position" : {
      "x" : 969,
      "y" : 365
    },
    "minX" : 896,
    "maxX" : 1030,
    "minY" : 347,
    "maxY" : 417,
    "prop" : {
      "x" : 908,
      "y" : 347,
      "width" : 122,
      "height" : 36
    },
    "textPosition" : {
      "x" : 923,
      "y" : 334
    },
    "connectors" : [ {
      "edgeId" : 75837,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 943,
          "y" : 389
        },
        "to" : {
          "x" : 896,
          "y" : 417
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 75841,
    "reactomeId" : 10320364,
    "displayName" : "CDC42:GTP",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 967,
      "y" : 527
    },
    "minX" : 844,
    "maxX" : 1014,
    "minY" : 458,
    "maxY" : 538,
    "prop" : {
      "x" : 927,
      "y" : 516,
      "width" : 81,
      "height" : 22
    },
    "textPosition" : {
      "x" : 929,
      "y" : 517
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1008,
          "y" : 516
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1008,
          "y" : 516
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 75840,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 75842,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 947,
          "y" : 513
        },
        "to" : {
          "x" : 844,
          "y" : 458
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 75843,
    "reactomeId" : 10320368,
    "displayName" : "CDC42 endoplasmic reticulum effectors",
    "schemaClass" : "CandidateSet",
    "renderableClass" : "EntitySet",
    "position" : {
      "x" : 829,
      "y" : 375
    },
    "minX" : 763,
    "maxX" : 896,
    "minY" : 360,
    "maxY" : 458,
    "prop" : {
      "x" : 763,
      "y" : 360,
      "width" : 133,
      "height" : 30
    },
    "textPosition" : {
      "x" : 762,
      "y" : 358
    },
    "connectors" : [ {
      "edgeId" : 75842,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 831,
          "y" : 396
        },
        "to" : {
          "x" : 844,
          "y" : 458
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 75844,
    "reactomeId" : 10320370,
    "displayName" : "CDC42:GTP:CDC42 endoplasmic reticulum effectors",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 957,
      "y" : 612
    },
    "minX" : 894,
    "maxX" : 1027,
    "minY" : 581,
    "maxY" : 637,
    "prop" : {
      "x" : 894,
      "y" : 587,
      "width" : 127,
      "height" : 50
    },
    "textPosition" : {
      "x" : 894,
      "y" : 588
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1021,
          "y" : 587
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1021,
          "y" : 587
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 75842,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 75847,
    "reactomeId" : 29438,
    "displayName" : "GTP",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 3111,
      "y" : 678
    },
    "minX" : 3094,
    "maxX" : 3188,
    "minY" : 664,
    "maxY" : 691,
    "prop" : {
      "x" : 3094,
      "y" : 665,
      "width" : 35,
      "height" : 26
    },
    "textPosition" : {
      "x" : 3095,
      "y" : 667
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 3124,
          "y" : 670
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 3124,
          "y" : 670
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 75845,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 3132,
          "y" : 679
        },
        "to" : {
          "x" : 3188,
          "y" : 684
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 75846,
    "reactomeId" : 10320386,
    "displayName" : "RHOF:GDP",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 3189,
      "y" : 646
    },
    "minX" : 3052,
    "maxX" : 3233,
    "minY" : 629,
    "maxY" : 712,
    "prop" : {
      "x" : 3151,
      "y" : 635,
      "width" : 76,
      "height" : 22
    },
    "textPosition" : {
      "x" : 3153,
      "y" : 636
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 3227,
          "y" : 635
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 3227,
          "y" : 635
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 75845,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 3188,
          "y" : 660
        },
        "to" : {
          "x" : 3188,
          "y" : 684
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 75845,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 3199,
          "y" : 660
        },
        "to" : {
          "x" : 3226,
          "y" : 685
        }
      }, {
        "from" : {
          "x" : 3226,
          "y" : 685
        },
        "to" : {
          "x" : 3199,
          "y" : 705
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 3196,
          "y" : 708
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 3196,
          "y" : 708
        }
      }
    }, {
      "edgeId" : 75850,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 3148,
          "y" : 645
        },
        "to" : {
          "x" : 3052,
          "y" : 645
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 3141,
          "y" : 649
        },
        "b" : {
          "x" : 3148,
          "y" : 645
        },
        "c" : {
          "x" : 3141,
          "y" : 641
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 3141,
          "y" : 641
        }
      }
    } ]
  }, {
    "id" : 75849,
    "reactomeId" : 29420,
    "displayName" : "GDP",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 3107,
      "y" : 747
    },
    "minX" : 3088,
    "maxX" : 3193,
    "minY" : 734,
    "maxY" : 760,
    "prop" : {
      "x" : 3088,
      "y" : 735,
      "width" : 38,
      "height" : 25
    },
    "textPosition" : {
      "x" : 3090,
      "y" : 737
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 3121,
          "y" : 740
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 3121,
          "y" : 740
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 75845,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 3129,
          "y" : 747
        },
        "to" : {
          "x" : 3193,
          "y" : 751
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 3136,
          "y" : 743
        },
        "b" : {
          "x" : 3129,
          "y" : 747
        },
        "c" : {
          "x" : 3136,
          "y" : 751
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 3136,
          "y" : 751
        }
      }
    } ]
  }, {
    "id" : 75848,
    "reactomeId" : 10320388,
    "displayName" : "RHOF:GTP",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 3184,
      "y" : 790
    },
    "minX" : 3052,
    "maxX" : 3226,
    "minY" : 751,
    "maxY" : 801,
    "prop" : {
      "x" : 3148,
      "y" : 779,
      "width" : 72,
      "height" : 22
    },
    "textPosition" : {
      "x" : 3149,
      "y" : 780
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 3220,
          "y" : 779
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 3220,
          "y" : 779
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 75845,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 3186,
          "y" : 776
        },
        "to" : {
          "x" : 3193,
          "y" : 751
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 3184,
          "y" : 768
        },
        "b" : {
          "x" : 3186,
          "y" : 776
        },
        "c" : {
          "x" : 3192,
          "y" : 770
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 3192,
          "y" : 770
        }
      }
    }, {
      "edgeId" : 75850,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 3145,
          "y" : 782
        },
        "to" : {
          "x" : 3052,
          "y" : 763
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 75854,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 3145,
          "y" : 793
        },
        "to" : {
          "x" : 3086,
          "y" : 800
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 75851,
    "reactomeId" : 29356,
    "displayName" : "H2O",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 3007,
      "y" : 779
    },
    "minX" : 2989,
    "maxX" : 3052,
    "minY" : 763,
    "maxY" : 789,
    "prop" : {
      "x" : 2989,
      "y" : 769,
      "width" : 36,
      "height" : 20
    },
    "textPosition" : {
      "x" : 2990,
      "y" : 769
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 3020,
          "y" : 774
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 3020,
          "y" : 774
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 75850,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 3028,
          "y" : 772
        },
        "to" : {
          "x" : 3052,
          "y" : 763
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ],
    "trivial" : true
  }, {
    "id" : 75853,
    "reactomeId" : 10320431,
    "displayName" : "RHOF GAPs",
    "schemaClass" : "CandidateSet",
    "renderableClass" : "EntitySet",
    "position" : {
      "x" : 2975,
      "y" : 713
    },
    "minX" : 2938,
    "maxX" : 3046,
    "minY" : 702,
    "maxY" : 725,
    "prop" : {
      "x" : 2938,
      "y" : 702,
      "width" : 75,
      "height" : 23
    },
    "textPosition" : {
      "x" : 2953,
      "y" : 696
    },
    "connectors" : [ {
      "edgeId" : 75850,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 3019,
          "y" : 712
        },
        "to" : {
          "x" : 3038,
          "y" : 712
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 3042,
          "y" : 712
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 3042,
          "y" : 712
        }
      }
    } ]
  }, {
    "id" : 75852,
    "reactomeId" : 29372,
    "displayName" : "Pi",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 3007,
      "y" : 635
    },
    "minX" : 2993,
    "maxX" : 3052,
    "minY" : 625,
    "maxY" : 645,
    "prop" : {
      "x" : 2993,
      "y" : 626,
      "width" : 29,
      "height" : 19
    },
    "textPosition" : {
      "x" : 2998,
      "y" : 625
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 3017,
          "y" : 631
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 3017,
          "y" : 631
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 75850,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 3025,
          "y" : 638
        },
        "to" : {
          "x" : 3052,
          "y" : 645
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 3033,
          "y" : 636
        },
        "b" : {
          "x" : 3025,
          "y" : 638
        },
        "c" : {
          "x" : 3031,
          "y" : 644
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 3031,
          "y" : 644
        }
      }
    } ]
  }, {
    "id" : 75855,
    "reactomeId" : 10320423,
    "displayName" : "RHOF effectors",
    "schemaClass" : "CandidateSet",
    "renderableClass" : "EntitySet",
    "position" : {
      "x" : 2948,
      "y" : 828
    },
    "minX" : 2899,
    "maxX" : 3086,
    "minY" : 800,
    "maxY" : 841,
    "prop" : {
      "x" : 2899,
      "y" : 816,
      "width" : 98,
      "height" : 25
    },
    "textPosition" : {
      "x" : 2916,
      "y" : 811
    },
    "connectors" : [ {
      "edgeId" : 75854,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 3003,
          "y" : 818
        },
        "to" : {
          "x" : 3086,
          "y" : 800
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 75856,
    "reactomeId" : 10320425,
    "displayName" : "RHOF:GTP:RHOF effectors",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 3188,
      "y" : 878
    },
    "minX" : 3141,
    "maxX" : 3242,
    "minY" : 854,
    "maxY" : 896,
    "prop" : {
      "x" : 3141,
      "y" : 860,
      "width" : 95,
      "height" : 36
    },
    "textPosition" : {
      "x" : 3152,
      "y" : 847
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 3236,
          "y" : 860
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 3236,
          "y" : 860
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 75854,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 75859,
    "reactomeId" : 10317116,
    "displayName" : "RHOH:GTP:RHOH GDIs",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 2960,
      "y" : 1933
    },
    "minX" : 2918,
    "maxX" : 3008,
    "minY" : 1909,
    "maxY" : 1951,
    "prop" : {
      "x" : 2918,
      "y" : 1915,
      "width" : 84,
      "height" : 36
    },
    "textPosition" : {
      "x" : 2922,
      "y" : 1916
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 3002,
          "y" : 1915
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 3002,
          "y" : 1915
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 75857,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 75858,
    "reactomeId" : 10316973,
    "displayName" : "ARHGDIA,ARHGDIB,ARHGDIG",
    "schemaClass" : "DefinedSet",
    "renderableClass" : "EntitySet",
    "position" : {
      "x" : 3004,
      "y" : 2023
    },
    "minX" : 2967,
    "maxX" : 3111,
    "minY" : 1996,
    "maxY" : 2047,
    "prop" : {
      "x" : 2967,
      "y" : 2000,
      "width" : 75,
      "height" : 47
    },
    "textPosition" : {
      "x" : 2971,
      "y" : 1999
    },
    "connectors" : [ {
      "edgeId" : 75857,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 3048,
          "y" : 2013
        },
        "to" : {
          "x" : 3111,
          "y" : 1996
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 75861,
    "reactomeId" : 10254063,
    "displayName" : "RND1",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 1741,
      "y" : 2415
    },
    "minX" : 1719,
    "maxX" : 1788,
    "minY" : 2398,
    "maxY" : 2426,
    "prop" : {
      "x" : 1719,
      "y" : 2404,
      "width" : 44,
      "height" : 22
    },
    "textPosition" : {
      "x" : 1720,
      "y" : 2404
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1763,
          "y" : 2404
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1763,
          "y" : 2404
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 75860,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1766,
          "y" : 2412
        },
        "to" : {
          "x" : 1788,
          "y" : 2410
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 75863,
    "reactomeId" : 10254065,
    "displayName" : "RND1:GTP",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 1897,
      "y" : 2411
    },
    "minX" : 1861,
    "maxX" : 1965,
    "minY" : 2395,
    "maxY" : 2422,
    "prop" : {
      "x" : 1861,
      "y" : 2401,
      "width" : 73,
      "height" : 21
    },
    "textPosition" : {
      "x" : 1862,
      "y" : 2401
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1934,
          "y" : 2401
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1934,
          "y" : 2401
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 75860,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 75864,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1937,
          "y" : 2412
        },
        "to" : {
          "x" : 1965,
          "y" : 2414
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 75862,
    "reactomeId" : 29438,
    "displayName" : "GTP",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 1772,
      "y" : 2366
    },
    "minX" : 1752,
    "maxX" : 1794,
    "minY" : 2350,
    "maxY" : 2410,
    "prop" : {
      "x" : 1752,
      "y" : 2351,
      "width" : 41,
      "height" : 30
    },
    "textPosition" : {
      "x" : 1756,
      "y" : 2355
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1788,
          "y" : 2356
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1788,
          "y" : 2356
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 75860,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1777,
          "y" : 2384
        },
        "to" : {
          "x" : 1788,
          "y" : 2410
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 75865,
    "reactomeId" : 10320565,
    "displayName" : "RND1 effectors",
    "schemaClass" : "CandidateSet",
    "renderableClass" : "EntitySet",
    "position" : {
      "x" : 1930,
      "y" : 2351
    },
    "minX" : 1881,
    "maxX" : 1979,
    "minY" : 2339,
    "maxY" : 2414,
    "prop" : {
      "x" : 1881,
      "y" : 2339,
      "width" : 98,
      "height" : 24
    },
    "textPosition" : {
      "x" : 1898,
      "y" : 2334
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 204
    },
    "fgColor" : {
      "r" : 0,
      "g" : 0,
      "b" : 0
    },
    "connectors" : [ {
      "edgeId" : 75864,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1936,
          "y" : 2369
        },
        "to" : {
          "x" : 1965,
          "y" : 2414
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 75866,
    "reactomeId" : 10320567,
    "displayName" : "RND1:GTP:RND1 effectors",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 2087,
      "y" : 2414
    },
    "minX" : 2039,
    "maxX" : 2142,
    "minY" : 2391,
    "maxY" : 2432,
    "prop" : {
      "x" : 2039,
      "y" : 2397,
      "width" : 97,
      "height" : 35
    },
    "textPosition" : {
      "x" : 2050,
      "y" : 2383
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 2136,
          "y" : 2397
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 2136,
          "y" : 2397
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 75864,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 75869,
    "reactomeId" : 29438,
    "displayName" : "GTP",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 2232,
      "y" : 2361
    },
    "minX" : 2214,
    "maxX" : 2251,
    "minY" : 2349,
    "maxY" : 2413,
    "prop" : {
      "x" : 2214,
      "y" : 2350,
      "width" : 36,
      "height" : 23
    },
    "textPosition" : {
      "x" : 2216,
      "y" : 2351
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 2245,
          "y" : 2355
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 2245,
          "y" : 2355
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 75867,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 2235,
          "y" : 2376
        },
        "to" : {
          "x" : 2250,
          "y" : 2413
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 75868,
    "reactomeId" : 10320477,
    "displayName" : "RND2",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 2193,
      "y" : 2413
    },
    "minX" : 2168,
    "maxX" : 2250,
    "minY" : 2396,
    "maxY" : 2424,
    "prop" : {
      "x" : 2168,
      "y" : 2402,
      "width" : 51,
      "height" : 22
    },
    "textPosition" : {
      "x" : 2172,
      "y" : 2402
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 2219,
          "y" : 2402
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 2219,
          "y" : 2402
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 75867,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 2222,
          "y" : 2413
        },
        "to" : {
          "x" : 2250,
          "y" : 2413
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 75870,
    "reactomeId" : 10320479,
    "displayName" : "RND2:GTP",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 2357,
      "y" : 2414
    },
    "minX" : 2319,
    "maxX" : 2432,
    "minY" : 2397,
    "maxY" : 2426,
    "prop" : {
      "x" : 2319,
      "y" : 2403,
      "width" : 77,
      "height" : 23
    },
    "textPosition" : {
      "x" : 2322,
      "y" : 2405
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 2396,
          "y" : 2403
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 2396,
          "y" : 2403
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 75867,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 75871,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 2399,
          "y" : 2411
        },
        "to" : {
          "x" : 2432,
          "y" : 2410
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 75873,
    "reactomeId" : 10320521,
    "displayName" : "RND2:GTP:RND2 effectors",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 2554,
      "y" : 2414
    },
    "minX" : 2505,
    "maxX" : 2610,
    "minY" : 2392,
    "maxY" : 2431,
    "prop" : {
      "x" : 2505,
      "y" : 2398,
      "width" : 99,
      "height" : 33
    },
    "textPosition" : {
      "x" : 2517,
      "y" : 2382
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 2604,
          "y" : 2398
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 2604,
          "y" : 2398
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 75871,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 75872,
    "reactomeId" : 10320519,
    "displayName" : "RND2 effectors",
    "schemaClass" : "CandidateSet",
    "renderableClass" : "EntitySet",
    "position" : {
      "x" : 2419,
      "y" : 2361
    },
    "minX" : 2370,
    "maxX" : 2469,
    "minY" : 2352,
    "maxY" : 2410,
    "prop" : {
      "x" : 2370,
      "y" : 2352,
      "width" : 99,
      "height" : 18
    },
    "textPosition" : {
      "x" : 2387,
      "y" : 2344
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 204
    },
    "fgColor" : {
      "r" : 0,
      "g" : 0,
      "b" : 0
    },
    "connectors" : [ {
      "edgeId" : 75871,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 2421,
          "y" : 2376
        },
        "to" : {
          "x" : 2432,
          "y" : 2410
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 75875,
    "reactomeId" : 10320527,
    "displayName" : "RND3",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 2670,
      "y" : 2413
    },
    "minX" : 2644,
    "maxX" : 2732,
    "minY" : 2396,
    "maxY" : 2425,
    "prop" : {
      "x" : 2644,
      "y" : 2402,
      "width" : 52,
      "height" : 23
    },
    "textPosition" : {
      "x" : 2649,
      "y" : 2403
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 2696,
          "y" : 2402
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 2696,
          "y" : 2402
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 75874,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 2699,
          "y" : 2413
        },
        "to" : {
          "x" : 2732,
          "y" : 2413
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 75877,
    "reactomeId" : 10320529,
    "displayName" : "RND3:GTP",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 2852,
      "y" : 2412
    },
    "minX" : 2814,
    "maxX" : 2935,
    "minY" : 2395,
    "maxY" : 2423,
    "prop" : {
      "x" : 2814,
      "y" : 2401,
      "width" : 77,
      "height" : 22
    },
    "textPosition" : {
      "x" : 2817,
      "y" : 2402
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 2891,
          "y" : 2401
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 2891,
          "y" : 2401
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 75874,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 75878,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 2894,
          "y" : 2412
        },
        "to" : {
          "x" : 2935,
          "y" : 2414
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 75876,
    "reactomeId" : 29438,
    "displayName" : "GTP",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 2717,
      "y" : 2363
    },
    "minX" : 2699,
    "maxX" : 2736,
    "minY" : 2351,
    "maxY" : 2413,
    "prop" : {
      "x" : 2699,
      "y" : 2352,
      "width" : 36,
      "height" : 23
    },
    "textPosition" : {
      "x" : 2701,
      "y" : 2353
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 2730,
          "y" : 2357
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 2730,
          "y" : 2357
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 75874,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 2720,
          "y" : 2378
        },
        "to" : {
          "x" : 2732,
          "y" : 2413
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 75879,
    "reactomeId" : 10320543,
    "displayName" : "RND3 effectors",
    "schemaClass" : "CandidateSet",
    "renderableClass" : "EntitySet",
    "position" : {
      "x" : 2916,
      "y" : 2346
    },
    "minX" : 2867,
    "maxX" : 2966,
    "minY" : 2336,
    "maxY" : 2414,
    "prop" : {
      "x" : 2867,
      "y" : 2336,
      "width" : 99,
      "height" : 20
    },
    "textPosition" : {
      "x" : 2884,
      "y" : 2329
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 204
    },
    "fgColor" : {
      "r" : 0,
      "g" : 0,
      "b" : 0
    },
    "connectors" : [ {
      "edgeId" : 75878,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 2918,
          "y" : 2362
        },
        "to" : {
          "x" : 2935,
          "y" : 2414
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 75880,
    "reactomeId" : 10320545,
    "displayName" : "RND3:GTP:RND3 effectors",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 3080,
      "y" : 2411
    },
    "minX" : 3032,
    "maxX" : 3134,
    "minY" : 2388,
    "maxY" : 2429,
    "prop" : {
      "x" : 3032,
      "y" : 2394,
      "width" : 96,
      "height" : 35
    },
    "textPosition" : {
      "x" : 3043,
      "y" : 2380
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 3128,
          "y" : 2394
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 3128,
          "y" : 2394
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 75878,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 75882,
    "reactomeId" : 10321623,
    "displayName" : "RAC2:GTP",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 918,
      "y" : 804
    },
    "minX" : 808,
    "maxX" : 959,
    "minY" : 668,
    "maxY" : 815,
    "prop" : {
      "x" : 884,
      "y" : 793,
      "width" : 69,
      "height" : 22
    },
    "textPosition" : {
      "x" : 884,
      "y" : 794
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 953,
          "y" : 793
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 953,
          "y" : 793
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 75881,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 75883,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 909,
          "y" : 790
        },
        "to" : {
          "x" : 808,
          "y" : 668
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 75885,
    "reactomeId" : 10321627,
    "displayName" : "RAC2:GTP:RAC2 endoplasmic reticulum effectors",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 691,
      "y" : 736
    },
    "minX" : 623,
    "maxX" : 765,
    "minY" : 707,
    "maxY" : 760,
    "prop" : {
      "x" : 623,
      "y" : 713,
      "width" : 136,
      "height" : 47
    },
    "textPosition" : {
      "x" : 628,
      "y" : 711
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 759,
          "y" : 713
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 759,
          "y" : 713
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 75883,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 75884,
    "reactomeId" : 10321625,
    "displayName" : "RAC2 endoplasmic reticulum effectors",
    "schemaClass" : "CandidateSet",
    "renderableClass" : "EntitySet",
    "position" : {
      "x" : 635,
      "y" : 630
    },
    "minX" : 569,
    "maxX" : 808,
    "minY" : 608,
    "maxY" : 668,
    "prop" : {
      "x" : 569,
      "y" : 608,
      "width" : 133,
      "height" : 44
    },
    "textPosition" : {
      "x" : 572,
      "y" : 612
    },
    "connectors" : [ {
      "edgeId" : 75883,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 708,
          "y" : 644
        },
        "to" : {
          "x" : 808,
          "y" : 668
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 75887,
    "reactomeId" : 10321595,
    "displayName" : "RAC2:GTP",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 2109,
      "y" : 558
    },
    "minX" : 2014,
    "maxX" : 2150,
    "minY" : 541,
    "maxY" : 590,
    "prop" : {
      "x" : 2075,
      "y" : 547,
      "width" : 69,
      "height" : 22
    },
    "textPosition" : {
      "x" : 2075,
      "y" : 548
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 2144,
          "y" : 547
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 2144,
          "y" : 547
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 75886,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 75888,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 2076,
          "y" : 572
        },
        "to" : {
          "x" : 2014,
          "y" : 590
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 75889,
    "reactomeId" : 10321609,
    "displayName" : "RAC2 mitochondrial effectors",
    "schemaClass" : "CandidateSet",
    "renderableClass" : "EntitySet",
    "position" : {
      "x" : 1725,
      "y" : 594
    },
    "minX" : 1660,
    "maxX" : 2014,
    "minY" : 574,
    "maxY" : 614,
    "prop" : {
      "x" : 1660,
      "y" : 574,
      "width" : 131,
      "height" : 40
    },
    "textPosition" : {
      "x" : 1659,
      "y" : 576
    },
    "connectors" : [ {
      "edgeId" : 75888,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1797,
          "y" : 593
        },
        "to" : {
          "x" : 2014,
          "y" : 590
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 75890,
    "reactomeId" : 10321611,
    "displayName" : "RAC2:GTP:RAC2 mitochondrial effectors",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 1873,
      "y" : 649
    },
    "minX" : 1798,
    "maxX" : 1954,
    "minY" : 627,
    "maxY" : 665,
    "prop" : {
      "x" : 1798,
      "y" : 633,
      "width" : 150,
      "height" : 32
    },
    "textPosition" : {
      "x" : 1819,
      "y" : 616
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1948,
          "y" : 633
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1948,
          "y" : 633
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 75888,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 75892,
    "reactomeId" : 10321575,
    "displayName" : "RHOC:GTP",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 638,
      "y" : 876
    },
    "minX" : 599,
    "maxX" : 747,
    "minY" : 859,
    "maxY" : 887,
    "prop" : {
      "x" : 599,
      "y" : 865,
      "width" : 78,
      "height" : 22
    },
    "textPosition" : {
      "x" : 603,
      "y" : 866
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 677,
          "y" : 865
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 677,
          "y" : 865
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 75891,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 75893,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 680,
          "y" : 869
        },
        "to" : {
          "x" : 747,
          "y" : 859
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 75895,
    "reactomeId" : 10321579,
    "displayName" : "RHOC:GTP:RHOC endoplasmic reticulum effectors",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 882,
      "y" : 891
    },
    "minX" : 817,
    "maxX" : 953,
    "minY" : 861,
    "maxY" : 916,
    "prop" : {
      "x" : 817,
      "y" : 867,
      "width" : 130,
      "height" : 49
    },
    "textPosition" : {
      "x" : 819,
      "y" : 867
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 947,
          "y" : 867
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 947,
          "y" : 867
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 75893,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 75894,
    "reactomeId" : 10321577,
    "displayName" : "RHOC endoplasmic reticulum effectors",
    "schemaClass" : "CandidateSet",
    "renderableClass" : "EntitySet",
    "position" : {
      "x" : 682,
      "y" : 810
    },
    "minX" : 618,
    "maxX" : 747,
    "minY" : 790,
    "maxY" : 859,
    "prop" : {
      "x" : 618,
      "y" : 790,
      "width" : 128,
      "height" : 41
    },
    "textPosition" : {
      "x" : 618,
      "y" : 793
    },
    "connectors" : [ {
      "edgeId" : 75893,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 709,
          "y" : 837
        },
        "to" : {
          "x" : 747,
          "y" : 859
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 75897,
    "reactomeId" : 10321767,
    "displayName" : "p-Y254-RHOU:GDP",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 1656,
      "y" : 2414
    },
    "minX" : 1619,
    "maxX" : 1700,
    "minY" : 2391,
    "maxY" : 2432,
    "prop" : {
      "x" : 1619,
      "y" : 2397,
      "width" : 75,
      "height" : 35
    },
    "textPosition" : {
      "x" : 1620,
      "y" : 2397
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1694,
          "y" : 2397
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1694,
          "y" : 2397
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 75896,
      "type" : "INPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 75898,
    "reactomeId" : 10321771,
    "displayName" : "p-Y254-RHOU:GDP",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 893,
      "y" : 2069
    },
    "minX" : 831,
    "maxX" : 962,
    "minY" : 2051,
    "maxY" : 2082,
    "prop" : {
      "x" : 831,
      "y" : 2057,
      "width" : 125,
      "height" : 25
    },
    "textPosition" : {
      "x" : 833,
      "y" : 2061
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 956,
          "y" : 2057
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 956,
          "y" : 2057
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 75896,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 75661,
    "reactomeId" : 29438,
    "displayName" : "GTP",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 437,
      "y" : 103
    },
    "minX" : 417,
    "maxX" : 484,
    "minY" : 62,
    "maxY" : 118,
    "prop" : {
      "x" : 417,
      "y" : 88,
      "width" : 41,
      "height" : 30
    },
    "textPosition" : {
      "x" : 421,
      "y" : 92
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 453,
          "y" : 93
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 453,
          "y" : 93
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 75660,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 454,
          "y" : 85
        },
        "to" : {
          "x" : 484,
          "y" : 62
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 75663,
    "reactomeId" : 29420,
    "displayName" : "GDP",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 584,
      "y" : 116
    },
    "minX" : 563,
    "maxX" : 606,
    "minY" : 64,
    "maxY" : 131,
    "prop" : {
      "x" : 563,
      "y" : 101,
      "width" : 42,
      "height" : 30
    },
    "textPosition" : {
      "x" : 567,
      "y" : 105
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 600,
          "y" : 106
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 600,
          "y" : 106
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 75660,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 578,
          "y" : 98
        },
        "to" : {
          "x" : 564,
          "y" : 64
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 572,
          "y" : 93
        },
        "b" : {
          "x" : 578,
          "y" : 98
        },
        "c" : {
          "x" : 579,
          "y" : 90
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 579,
          "y" : 90
        }
      }
    } ]
  }, {
    "id" : 75662,
    "reactomeId" : 10234791,
    "displayName" : "RHOA:GDP",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 380,
      "y" : 64
    },
    "minX" : 303,
    "maxX" : 484,
    "minY" : 47,
    "maxY" : 211,
    "prop" : {
      "x" : 344,
      "y" : 53,
      "width" : 72,
      "height" : 22
    },
    "textPosition" : {
      "x" : 344,
      "y" : 54
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 416,
          "y" : 53
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 416,
          "y" : 53
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 75660,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 419,
          "y" : 63
        },
        "to" : {
          "x" : 484,
          "y" : 62
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 75666,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 383,
          "y" : 78
        },
        "to" : {
          "x" : 421,
          "y" : 211
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 389,
          "y" : 84
        },
        "b" : {
          "x" : 383,
          "y" : 78
        },
        "c" : {
          "x" : 381,
          "y" : 86
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 381,
          "y" : 86
        }
      }
    }, {
      "edgeId" : 75670,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 363,
          "y" : 78
        },
        "to" : {
          "x" : 303,
          "y" : 114
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 75665,
    "reactomeId" : 10315096,
    "displayName" : "RHOA GEFs",
    "schemaClass" : "CandidateSet",
    "renderableClass" : "EntitySet",
    "position" : {
      "x" : 524,
      "y" : 155
    },
    "minX" : 482,
    "maxX" : 567,
    "minY" : 73,
    "maxY" : 169,
    "prop" : {
      "x" : 482,
      "y" : 142,
      "width" : 85,
      "height" : 27
    },
    "textPosition" : {
      "x" : 486,
      "y" : 145
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 204
    },
    "fgColor" : {
      "r" : 0,
      "g" : 0,
      "b" : 0
    },
    "connectors" : [ {
      "edgeId" : 75660,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 524,
          "y" : 136
        },
        "to" : {
          "x" : 525,
          "y" : 81
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 525,
          "y" : 77
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 525,
          "y" : 77
        }
      }
    } ]
  }, {
    "id" : 75664,
    "reactomeId" : 10234793,
    "displayName" : "RHOA:GTP",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 643,
      "y" : 65
    },
    "minX" : 564,
    "maxX" : 698,
    "minY" : 48,
    "maxY" : 212,
    "prop" : {
      "x" : 608,
      "y" : 54,
      "width" : 71,
      "height" : 22
    },
    "textPosition" : {
      "x" : 608,
      "y" : 55
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 679,
          "y" : 54
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 679,
          "y" : 54
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 75660,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 605,
          "y" : 64
        },
        "to" : {
          "x" : 564,
          "y" : 64
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 598,
          "y" : 68
        },
        "b" : {
          "x" : 605,
          "y" : 64
        },
        "c" : {
          "x" : 598,
          "y" : 60
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 598,
          "y" : 60
        }
      }
    }, {
      "edgeId" : 75666,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 639,
          "y" : 79
        },
        "to" : {
          "x" : 592,
          "y" : 212
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 75673,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 682,
          "y" : 67
        },
        "to" : {
          "x" : 698,
          "y" : 69
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 75676,
      "type" : "INPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 75667,
    "reactomeId" : 29356,
    "displayName" : "H2O",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 611,
      "y" : 247
    },
    "minX" : 591,
    "maxX" : 632,
    "minY" : 212,
    "maxY" : 260,
    "prop" : {
      "x" : 591,
      "y" : 235,
      "width" : 40,
      "height" : 25
    },
    "textPosition" : {
      "x" : 594,
      "y" : 237
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 626,
          "y" : 240
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 626,
          "y" : 240
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 75666,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 604,
          "y" : 232
        },
        "to" : {
          "x" : 592,
          "y" : 212
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ],
    "trivial" : true
  }, {
    "id" : 75669,
    "reactomeId" : 10315296,
    "displayName" : "RHOA GAPs",
    "schemaClass" : "CandidateSet",
    "renderableClass" : "EntitySet",
    "position" : {
      "x" : 525,
      "y" : 279
    },
    "minX" : 486,
    "maxX" : 565,
    "minY" : 224,
    "maxY" : 290,
    "prop" : {
      "x" : 486,
      "y" : 268,
      "width" : 79,
      "height" : 22
    },
    "textPosition" : {
      "x" : 486,
      "y" : 268
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 204
    },
    "fgColor" : {
      "r" : 0,
      "g" : 0,
      "b" : 0
    },
    "connectors" : [ {
      "edgeId" : 75666,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 525,
          "y" : 262
        },
        "to" : {
          "x" : 526,
          "y" : 232
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 526,
          "y" : 228
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 526,
          "y" : 228
        }
      }
    } ]
  }, {
    "id" : 75668,
    "reactomeId" : 29372,
    "displayName" : "Pi",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 403,
      "y" : 256
    },
    "minX" : 231,
    "maxX" : 421,
    "minY" : 211,
    "maxY" : 400,
    "prop" : {
      "x" : 388,
      "y" : 244,
      "width" : 31,
      "height" : 24
    },
    "textPosition" : {
      "x" : 394,
      "y" : 245
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 414,
          "y" : 249
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 414,
          "y" : 249
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 75666,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 407,
          "y" : 241
        },
        "to" : {
          "x" : 421,
          "y" : 211
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 406,
          "y" : 233
        },
        "b" : {
          "x" : 407,
          "y" : 241
        },
        "c" : {
          "x" : 414,
          "y" : 236
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 414,
          "y" : 236
        }
      }
    }, {
      "edgeId" : 75798,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 388,
          "y" : 271
        },
        "to" : {
          "x" : 231,
          "y" : 400
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 385,
          "y" : 278
        },
        "b" : {
          "x" : 388,
          "y" : 271
        },
        "c" : {
          "x" : 380,
          "y" : 272
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 380,
          "y" : 272
        }
      }
    } ]
  }, {
    "id" : 75671,
    "reactomeId" : 10316532,
    "displayName" : "ARHGDIA,ARHGDIB",
    "schemaClass" : "DefinedSet",
    "renderableClass" : "EntitySet",
    "position" : {
      "x" : 231,
      "y" : 120
    },
    "minX" : 188,
    "maxX" : 913,
    "minY" : 0,
    "maxY" : 134,
    "prop" : {
      "x" : 188,
      "y" : 107,
      "width" : 87,
      "height" : 27
    },
    "textPosition" : {
      "x" : 198,
      "y" : 103
    },
    "connectors" : [ {
      "edgeId" : 75670,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 281,
          "y" : 116
        },
        "to" : {
          "x" : 303,
          "y" : 114
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 75707,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 231,
          "y" : 101
        },
        "to" : {
          "x" : 232,
          "y" : 0
        }
      }, {
        "from" : {
          "x" : 232,
          "y" : 0
        },
        "to" : {
          "x" : 894,
          "y" : 2
        }
      }, {
        "from" : {
          "x" : 894,
          "y" : 2
        },
        "to" : {
          "x" : 913,
          "y" : 131
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 75672,
    "reactomeId" : 10316536,
    "displayName" : "RHOA GDIs:RHOA:GDP",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 268,
      "y" : 261
    },
    "minX" : 227,
    "maxX" : 316,
    "minY" : 236,
    "maxY" : 280,
    "prop" : {
      "x" : 227,
      "y" : 242,
      "width" : 83,
      "height" : 38
    },
    "textPosition" : {
      "x" : 229,
      "y" : 245
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 310,
          "y" : 242
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 310,
          "y" : 242
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 75670,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 75675,
    "reactomeId" : 10316624,
    "displayName" : "RHOA:GTP:cytosolic RHOA effectors",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 799,
      "y" : 63
    },
    "minX" : 752,
    "maxX" : 852,
    "minY" : 32,
    "maxY" : 89,
    "prop" : {
      "x" : 752,
      "y" : 38,
      "width" : 94,
      "height" : 51
    },
    "textPosition" : {
      "x" : 762,
      "y" : 26
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 846,
          "y" : 38
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 846,
          "y" : 38
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 75673,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 75674,
    "reactomeId" : 10316622,
    "displayName" : "RHOA plasma membrane effectors",
    "schemaClass" : "CandidateSet",
    "renderableClass" : "EntitySet",
    "position" : {
      "x" : 736,
      "y" : 155
    },
    "minX" : 683,
    "maxX" : 789,
    "minY" : 69,
    "maxY" : 178,
    "prop" : {
      "x" : 683,
      "y" : 133,
      "width" : 106,
      "height" : 45
    },
    "textPosition" : {
      "x" : 688,
      "y" : 131
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 204
    },
    "fgColor" : {
      "r" : 0,
      "g" : 0,
      "b" : 0
    },
    "connectors" : [ {
      "edgeId" : 75673,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 726,
          "y" : 127
        },
        "to" : {
          "x" : 698,
          "y" : 69
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 75677,
    "reactomeId" : 10316540,
    "displayName" : "RHOA:GTP",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 660,
      "y" : 308
    },
    "minX" : 625,
    "maxX" : 743,
    "minY" : 263,
    "maxY" : 319,
    "prop" : {
      "x" : 625,
      "y" : 297,
      "width" : 71,
      "height" : 22
    },
    "textPosition" : {
      "x" : 625,
      "y" : 298
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 696,
          "y" : 297
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 696,
          "y" : 297
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 75676,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 75678,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 680,
          "y" : 294
        },
        "to" : {
          "x" : 743,
          "y" : 263
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 75679,
    "reactomeId" : 10316572,
    "displayName" : "RHOA endoplasmic reticulum effectors",
    "schemaClass" : "CandidateSet",
    "renderableClass" : "EntitySet",
    "position" : {
      "x" : 770,
      "y" : 319
    },
    "minX" : 708,
    "maxX" : 832,
    "minY" : 263,
    "maxY" : 337,
    "prop" : {
      "x" : 708,
      "y" : 301,
      "width" : 124,
      "height" : 36
    },
    "textPosition" : {
      "x" : 724,
      "y" : 288
    },
    "connectors" : [ {
      "edgeId" : 75678,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 761,
          "y" : 295
        },
        "to" : {
          "x" : 743,
          "y" : 263
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 75680,
    "reactomeId" : 10316574,
    "displayName" : "RHOA:GTP:RHOA endoplasmic reticulum effectors",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 955,
      "y" : 312
    },
    "minX" : 897,
    "maxX" : 1019,
    "minY" : 281,
    "maxY" : 337,
    "prop" : {
      "x" : 897,
      "y" : 287,
      "width" : 116,
      "height" : 50
    },
    "textPosition" : {
      "x" : 899,
      "y" : 274
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1013,
          "y" : 287
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1013,
          "y" : 287
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 75678,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 75683,
    "reactomeId" : 29438,
    "displayName" : "GTP",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 120,
      "y" : 1470
    },
    "minX" : 54,
    "maxX" : 140,
    "minY" : 1456,
    "maxY" : 1483,
    "prop" : {
      "x" : 101,
      "y" : 1457,
      "width" : 38,
      "height" : 26
    },
    "textPosition" : {
      "x" : 104,
      "y" : 1459
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 134,
          "y" : 1462
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 134,
          "y" : 1462
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 75681,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 98,
          "y" : 1472
        },
        "to" : {
          "x" : 54,
          "y" : 1479
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 75682,
    "reactomeId" : 10316628,
    "displayName" : "RHOC:GDP",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 58,
      "y" : 1424
    },
    "minX" : 22,
    "maxX" : 230,
    "minY" : 1400,
    "maxY" : 1479,
    "prop" : {
      "x" : 22,
      "y" : 1413,
      "width" : 73,
      "height" : 22
    },
    "textPosition" : {
      "x" : 22,
      "y" : 1414
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 95,
          "y" : 1413
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 95,
          "y" : 1413
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 75681,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 57,
          "y" : 1438
        },
        "to" : {
          "x" : 54,
          "y" : 1479
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 75687,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 98,
          "y" : 1428
        },
        "to" : {
          "x" : 230,
          "y" : 1445
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 105,
          "y" : 1425
        },
        "b" : {
          "x" : 98,
          "y" : 1428
        },
        "c" : {
          "x" : 104,
          "y" : 1433
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 104,
          "y" : 1433
        }
      }
    }, {
      "edgeId" : 75691,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 98,
          "y" : 1416
        },
        "to" : {
          "x" : 180,
          "y" : 1400
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 75685,
    "reactomeId" : 29420,
    "displayName" : "GDP",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 142,
      "y" : 1567
    },
    "minX" : 52,
    "maxX" : 162,
    "minY" : 1552,
    "maxY" : 1581,
    "prop" : {
      "x" : 123,
      "y" : 1553,
      "width" : 38,
      "height" : 28
    },
    "textPosition" : {
      "x" : 125,
      "y" : 1556
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 156,
          "y" : 1558
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 156,
          "y" : 1558
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 75681,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 120,
          "y" : 1566
        },
        "to" : {
          "x" : 52,
          "y" : 1565
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 113,
          "y" : 1570
        },
        "b" : {
          "x" : 120,
          "y" : 1566
        },
        "c" : {
          "x" : 113,
          "y" : 1562
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 113,
          "y" : 1562
        }
      }
    } ]
  }, {
    "id" : 75684,
    "reactomeId" : 10292206,
    "displayName" : "RHOC:GTP",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 52,
      "y" : 1616
    },
    "minX" : 16,
    "maxX" : 231,
    "minY" : 1565,
    "maxY" : 1656,
    "prop" : {
      "x" : 16,
      "y" : 1605,
      "width" : 73,
      "height" : 22
    },
    "textPosition" : {
      "x" : 17,
      "y" : 1606
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 89,
          "y" : 1605
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 89,
          "y" : 1605
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 75681,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 52,
          "y" : 1602
        },
        "to" : {
          "x" : 52,
          "y" : 1565
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 48,
          "y" : 1595
        },
        "b" : {
          "x" : 52,
          "y" : 1602
        },
        "c" : {
          "x" : 56,
          "y" : 1595
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 56,
          "y" : 1595
        }
      }
    }, {
      "edgeId" : 75687,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 92,
          "y" : 1610
        },
        "to" : {
          "x" : 231,
          "y" : 1587
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 75694,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 57,
          "y" : 1630
        },
        "to" : {
          "x" : 72,
          "y" : 1656
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 75891,
      "type" : "INPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 75686,
    "reactomeId" : 10316638,
    "displayName" : "RHOC GEFs",
    "schemaClass" : "DefinedSet",
    "renderableClass" : "EntitySet",
    "position" : {
      "x" : 144,
      "y" : 1515
    },
    "minX" : 59,
    "maxX" : 182,
    "minY" : 1504,
    "maxY" : 1526,
    "prop" : {
      "x" : 106,
      "y" : 1504,
      "width" : 76,
      "height" : 22
    },
    "textPosition" : {
      "x" : 121,
      "y" : 1498
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 204
    },
    "fgColor" : {
      "r" : 0,
      "g" : 0,
      "b" : 0
    },
    "connectors" : [ {
      "edgeId" : 75681,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 100,
          "y" : 1515
        },
        "to" : {
          "x" : 67,
          "y" : 1516
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 63,
          "y" : 1517
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 63,
          "y" : 1517
        }
      }
    } ]
  }, {
    "id" : 75689,
    "reactomeId" : 29372,
    "displayName" : "Pi",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 270,
      "y" : 1420
    },
    "minX" : 230,
    "maxX" : 287,
    "minY" : 1407,
    "maxY" : 1445,
    "prop" : {
      "x" : 255,
      "y" : 1408,
      "width" : 31,
      "height" : 24
    },
    "textPosition" : {
      "x" : 261,
      "y" : 1409
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 281,
          "y" : 1413
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 281,
          "y" : 1413
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 75687,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 252,
          "y" : 1429
        },
        "to" : {
          "x" : 230,
          "y" : 1445
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 249,
          "y" : 1436
        },
        "b" : {
          "x" : 252,
          "y" : 1429
        },
        "c" : {
          "x" : 244,
          "y" : 1430
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 244,
          "y" : 1430
        }
      }
    } ]
  }, {
    "id" : 75688,
    "reactomeId" : 29356,
    "displayName" : "H2O",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 264,
      "y" : 1623
    },
    "minX" : 231,
    "maxX" : 284,
    "minY" : 1587,
    "maxY" : 1636,
    "prop" : {
      "x" : 245,
      "y" : 1610,
      "width" : 38,
      "height" : 26
    },
    "textPosition" : {
      "x" : 247,
      "y" : 1612
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 278,
          "y" : 1615
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 278,
          "y" : 1615
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 75687,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 252,
          "y" : 1607
        },
        "to" : {
          "x" : 231,
          "y" : 1587
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ],
    "trivial" : true
  }, {
    "id" : 75690,
    "reactomeId" : 10316653,
    "displayName" : "RHOC GAPs",
    "schemaClass" : "CandidateSet",
    "renderableClass" : "EntitySet",
    "position" : {
      "x" : 327,
      "y" : 1512
    },
    "minX" : 239,
    "maxX" : 367,
    "minY" : 1501,
    "maxY" : 1523,
    "prop" : {
      "x" : 288,
      "y" : 1501,
      "width" : 79,
      "height" : 22
    },
    "textPosition" : {
      "x" : 288,
      "y" : 1501
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 204
    },
    "fgColor" : {
      "r" : 0,
      "g" : 0,
      "b" : 0
    },
    "connectors" : [ {
      "edgeId" : 75687,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 282,
          "y" : 1511
        },
        "to" : {
          "x" : 247,
          "y" : 1511
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 243,
          "y" : 1511
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 243,
          "y" : 1511
        }
      }
    } ]
  }, {
    "id" : 75693,
    "reactomeId" : 10316634,
    "displayName" : "RHOC:GDP:ARHGDIA",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 368,
      "y" : 1365
    },
    "minX" : 327,
    "maxX" : 416,
    "minY" : 1341,
    "maxY" : 1383,
    "prop" : {
      "x" : 327,
      "y" : 1347,
      "width" : 83,
      "height" : 36
    },
    "textPosition" : {
      "x" : 330,
      "y" : 1348
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 410,
          "y" : 1347
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 410,
          "y" : 1347
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 75691,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 75692,
    "reactomeId" : 10242465,
    "displayName" : "ARHGDIA",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 144,
      "y" : 1364
    },
    "minX" : 113,
    "maxX" : 182,
    "minY" : 1347,
    "maxY" : 1400,
    "prop" : {
      "x" : 113,
      "y" : 1353,
      "width" : 63,
      "height" : 22
    },
    "textPosition" : {
      "x" : 113,
      "y" : 1353
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 176,
          "y" : 1353
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 176,
          "y" : 1353
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 75691,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 155,
          "y" : 1378
        },
        "to" : {
          "x" : 180,
          "y" : 1400
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 75695,
    "reactomeId" : 10316647,
    "displayName" : "RHOC effectors",
    "schemaClass" : "CandidateSet",
    "renderableClass" : "EntitySet",
    "position" : {
      "x" : 158,
      "y" : 1683
    },
    "minX" : 72,
    "maxX" : 207,
    "minY" : 1656,
    "maxY" : 1694,
    "prop" : {
      "x" : 109,
      "y" : 1673,
      "width" : 98,
      "height" : 21
    },
    "textPosition" : {
      "x" : 126,
      "y" : 1666
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 204
    },
    "fgColor" : {
      "r" : 0,
      "g" : 0,
      "b" : 0
    },
    "connectors" : [ {
      "edgeId" : 75694,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 124,
          "y" : 1667
        },
        "to" : {
          "x" : 72,
          "y" : 1656
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 75696,
    "reactomeId" : 10316649,
    "displayName" : "RHOC:GTP:RHOC effectors",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 56,
      "y" : 1807
    },
    "minX" : 4,
    "maxX" : 115,
    "minY" : 1785,
    "maxY" : 1824,
    "prop" : {
      "x" : 4,
      "y" : 1791,
      "width" : 105,
      "height" : 33
    },
    "textPosition" : {
      "x" : 5,
      "y" : 1789
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 109,
          "y" : 1791
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 109,
          "y" : 1791
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 75694,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 75699,
    "reactomeId" : 29438,
    "displayName" : "GTP",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 1002,
      "y" : 102
    },
    "minX" : 982,
    "maxX" : 1025,
    "minY" : 65,
    "maxY" : 114,
    "prop" : {
      "x" : 982,
      "y" : 91,
      "width" : 40,
      "height" : 23
    },
    "textPosition" : {
      "x" : 986,
      "y" : 92
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1017,
          "y" : 96
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1017,
          "y" : 96
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 75697,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1009,
          "y" : 88
        },
        "to" : {
          "x" : 1025,
          "y" : 65
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 75698,
    "reactomeId" : 10275414,
    "displayName" : "RAC1:GDP",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 949,
      "y" : 62
    },
    "minX" : 913,
    "maxX" : 1025,
    "minY" : 45,
    "maxY" : 173,
    "prop" : {
      "x" : 914,
      "y" : 51,
      "width" : 70,
      "height" : 22
    },
    "textPosition" : {
      "x" : 914,
      "y" : 52
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 984,
          "y" : 51
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 984,
          "y" : 51
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 75697,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 987,
          "y" : 63
        },
        "to" : {
          "x" : 1025,
          "y" : 65
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 75703,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 951,
          "y" : 76
        },
        "to" : {
          "x" : 978,
          "y" : 173
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 957,
          "y" : 82
        },
        "b" : {
          "x" : 951,
          "y" : 76
        },
        "c" : {
          "x" : 949,
          "y" : 84
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 949,
          "y" : 84
        }
      }
    }, {
      "edgeId" : 75707,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 943,
          "y" : 76
        },
        "to" : {
          "x" : 913,
          "y" : 131
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 75701,
    "reactomeId" : 29420,
    "displayName" : "GDP",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 1136,
      "y" : 108
    },
    "minX" : 1101,
    "maxX" : 1157,
    "minY" : 60,
    "maxY" : 120,
    "prop" : {
      "x" : 1116,
      "y" : 96,
      "width" : 40,
      "height" : 24
    },
    "textPosition" : {
      "x" : 1119,
      "y" : 97
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1151,
          "y" : 101
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1151,
          "y" : 101
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 75697,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 1127,
          "y" : 93
        },
        "to" : {
          "x" : 1101,
          "y" : 60
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 1120,
          "y" : 90
        },
        "b" : {
          "x" : 1127,
          "y" : 93
        },
        "c" : {
          "x" : 1126,
          "y" : 85
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 1126,
          "y" : 85
        }
      }
    } ]
  }, {
    "id" : 75700,
    "reactomeId" : 10234753,
    "displayName" : "RAC1:GTP",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 1214,
      "y" : 75
    },
    "minX" : 1101,
    "maxX" : 1306,
    "minY" : 58,
    "maxY" : 185,
    "prop" : {
      "x" : 1180,
      "y" : 64,
      "width" : 69,
      "height" : 22
    },
    "textPosition" : {
      "x" : 1180,
      "y" : 65
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1249,
          "y" : 64
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1249,
          "y" : 64
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 75697,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 1177,
          "y" : 70
        },
        "to" : {
          "x" : 1101,
          "y" : 60
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 1170,
          "y" : 73
        },
        "b" : {
          "x" : 1177,
          "y" : 70
        },
        "c" : {
          "x" : 1171,
          "y" : 65
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 1171,
          "y" : 65
        }
      }
    }, {
      "edgeId" : 75703,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1205,
          "y" : 89
        },
        "to" : {
          "x" : 1129,
          "y" : 185
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 75835,
      "type" : "INPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 75709,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1252,
          "y" : 85
        },
        "to" : {
          "x" : 1306,
          "y" : 102
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 75702,
    "reactomeId" : 10316674,
    "displayName" : "RAC1 GEFs",
    "schemaClass" : "CandidateSet",
    "renderableClass" : "EntitySet",
    "position" : {
      "x" : 1064,
      "y" : 136
    },
    "minX" : 1028,
    "maxX" : 1101,
    "minY" : 67,
    "maxY" : 147,
    "prop" : {
      "x" : 1028,
      "y" : 125,
      "width" : 73,
      "height" : 22
    },
    "textPosition" : {
      "x" : 1042,
      "y" : 119
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 204
    },
    "fgColor" : {
      "r" : 0,
      "g" : 0,
      "b" : 0
    },
    "connectors" : [ {
      "edgeId" : 75697,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 1064,
          "y" : 119
        },
        "to" : {
          "x" : 1065,
          "y" : 75
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 1065,
          "y" : 71
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1065,
          "y" : 71
        }
      }
    } ]
  }, {
    "id" : 75705,
    "reactomeId" : 29372,
    "displayName" : "Pi",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 917,
      "y" : 207
    },
    "minX" : 902,
    "maxX" : 978,
    "minY" : 173,
    "maxY" : 219,
    "prop" : {
      "x" : 902,
      "y" : 195,
      "width" : 31,
      "height" : 24
    },
    "textPosition" : {
      "x" : 908,
      "y" : 196
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 928,
          "y" : 200
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 928,
          "y" : 200
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 75703,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 936,
          "y" : 198
        },
        "to" : {
          "x" : 978,
          "y" : 173
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 940,
          "y" : 191
        },
        "b" : {
          "x" : 936,
          "y" : 198
        },
        "c" : {
          "x" : 944,
          "y" : 198
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 944,
          "y" : 198
        }
      }
    } ]
  }, {
    "id" : 75704,
    "reactomeId" : 29356,
    "displayName" : "H2O",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 1170,
      "y" : 218
    },
    "minX" : 1129,
    "maxX" : 1193,
    "minY" : 185,
    "maxY" : 233,
    "prop" : {
      "x" : 1149,
      "y" : 203,
      "width" : 43,
      "height" : 30
    },
    "textPosition" : {
      "x" : 1153,
      "y" : 207
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1187,
          "y" : 208
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1187,
          "y" : 208
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 75703,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1151,
          "y" : 200
        },
        "to" : {
          "x" : 1129,
          "y" : 185
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ],
    "trivial" : true
  }, {
    "id" : 75706,
    "reactomeId" : 10316731,
    "displayName" : "RAC1 GAPs",
    "schemaClass" : "CandidateSet",
    "renderableClass" : "EntitySet",
    "position" : {
      "x" : 1065,
      "y" : 229
    },
    "minX" : 1028,
    "maxX" : 1103,
    "minY" : 183,
    "maxY" : 240,
    "prop" : {
      "x" : 1028,
      "y" : 218,
      "width" : 75,
      "height" : 22
    },
    "textPosition" : {
      "x" : 1043,
      "y" : 212
    },
    "connectors" : [ {
      "edgeId" : 75703,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 1065,
          "y" : 212
        },
        "to" : {
          "x" : 1067,
          "y" : 191
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 1067,
          "y" : 187
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1067,
          "y" : 187
        }
      }
    } ]
  }, {
    "id" : 75708,
    "reactomeId" : 10316802,
    "displayName" : "RAC1:GDP:RAC1 GDIs",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 842,
      "y" : 241
    },
    "minX" : 805,
    "maxX" : 886,
    "minY" : 217,
    "maxY" : 260,
    "prop" : {
      "x" : 805,
      "y" : 223,
      "width" : 75,
      "height" : 37
    },
    "textPosition" : {
      "x" : 805,
      "y" : 225
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 880,
          "y" : 223
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 880,
          "y" : 223
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 75707,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 75711,
    "reactomeId" : 10316798,
    "displayName" : "RAC1:GTP:RAC1 effectors",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 1420,
      "y" : 64
    },
    "minX" : 1372,
    "maxX" : 1474,
    "minY" : 39,
    "maxY" : 84,
    "prop" : {
      "x" : 1372,
      "y" : 45,
      "width" : 96,
      "height" : 39
    },
    "textPosition" : {
      "x" : 1384,
      "y" : 35
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1468,
          "y" : 45
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1468,
          "y" : 45
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 75709,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 75710,
    "reactomeId" : 10316796,
    "displayName" : "RAC1 effectors",
    "schemaClass" : "CandidateSet",
    "renderableClass" : "EntitySet",
    "position" : {
      "x" : 1280,
      "y" : 161
    },
    "minX" : 1233,
    "maxX" : 1328,
    "minY" : 102,
    "maxY" : 172,
    "prop" : {
      "x" : 1233,
      "y" : 150,
      "width" : 95,
      "height" : 22
    },
    "textPosition" : {
      "x" : 1248,
      "y" : 144
    },
    "connectors" : [ {
      "edgeId" : 75709,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1284,
          "y" : 144
        },
        "to" : {
          "x" : 1306,
          "y" : 102
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 75713,
    "reactomeId" : 10316854,
    "displayName" : "CDC42:GDP",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 1569,
      "y" : 62
    },
    "minX" : 1469,
    "maxX" : 1663,
    "minY" : 44,
    "maxY" : 198,
    "prop" : {
      "x" : 1530,
      "y" : 50,
      "width" : 78,
      "height" : 25
    },
    "textPosition" : {
      "x" : 1542,
      "y" : 40
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1608,
          "y" : 50
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1608,
          "y" : 50
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 75712,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1611,
          "y" : 63
        },
        "to" : {
          "x" : 1663,
          "y" : 66
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 75718,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 1569,
          "y" : 78
        },
        "to" : {
          "x" : 1577,
          "y" : 198
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 1573,
          "y" : 85
        },
        "b" : {
          "x" : 1569,
          "y" : 78
        },
        "c" : {
          "x" : 1565,
          "y" : 85
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 1565,
          "y" : 85
        }
      }
    }, {
      "edgeId" : 75722,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1557,
          "y" : 78
        },
        "to" : {
          "x" : 1469,
          "y" : 174
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 75715,
    "reactomeId" : 10240940,
    "displayName" : "CDC42:GTP",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 1843,
      "y" : 63
    },
    "minX" : 1753,
    "maxX" : 1942,
    "minY" : 45,
    "maxY" : 189,
    "prop" : {
      "x" : 1801,
      "y" : 51,
      "width" : 85,
      "height" : 24
    },
    "textPosition" : {
      "x" : 1805,
      "y" : 54
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1886,
          "y" : 51
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1886,
          "y" : 51
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 75712,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 1798,
          "y" : 63
        },
        "to" : {
          "x" : 1753,
          "y" : 64
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 1791,
          "y" : 67
        },
        "b" : {
          "x" : 1798,
          "y" : 63
        },
        "c" : {
          "x" : 1791,
          "y" : 59
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 1791,
          "y" : 59
        }
      }
    }, {
      "edgeId" : 75840,
      "type" : "INPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 75718,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1840,
          "y" : 78
        },
        "to" : {
          "x" : 1812,
          "y" : 189
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 75725,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1858,
          "y" : 78
        },
        "to" : {
          "x" : 1942,
          "y" : 138
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 75714,
    "reactomeId" : 29438,
    "displayName" : "GTP",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 1603,
      "y" : 116
    },
    "minX" : 1583,
    "maxX" : 1663,
    "minY" : 66,
    "maxY" : 131,
    "prop" : {
      "x" : 1583,
      "y" : 101,
      "width" : 41,
      "height" : 30
    },
    "textPosition" : {
      "x" : 1587,
      "y" : 105
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1619,
          "y" : 106
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1619,
          "y" : 106
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 75712,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1621,
          "y" : 98
        },
        "to" : {
          "x" : 1663,
          "y" : 66
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 75717,
    "reactomeId" : 10316872,
    "displayName" : "CDC42 GEFs",
    "schemaClass" : "CandidateSet",
    "renderableClass" : "EntitySet",
    "position" : {
      "x" : 1697,
      "y" : 144
    },
    "minX" : 1656,
    "maxX" : 1738,
    "minY" : 74,
    "maxY" : 155,
    "prop" : {
      "x" : 1656,
      "y" : 133,
      "width" : 82,
      "height" : 22
    },
    "textPosition" : {
      "x" : 1670,
      "y" : 127
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 204
    },
    "fgColor" : {
      "r" : 0,
      "g" : 0,
      "b" : 0
    },
    "connectors" : [ {
      "edgeId" : 75712,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 1697,
          "y" : 127
        },
        "to" : {
          "x" : 1701,
          "y" : 82
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 1702,
          "y" : 78
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1702,
          "y" : 78
        }
      }
    } ]
  }, {
    "id" : 75716,
    "reactomeId" : 29420,
    "displayName" : "GDP",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 1783,
      "y" : 123
    },
    "minX" : 1753,
    "maxX" : 1805,
    "minY" : 64,
    "maxY" : 138,
    "prop" : {
      "x" : 1762,
      "y" : 108,
      "width" : 42,
      "height" : 30
    },
    "textPosition" : {
      "x" : 1766,
      "y" : 112
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1799,
          "y" : 113
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1799,
          "y" : 113
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 75712,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 1775,
          "y" : 105
        },
        "to" : {
          "x" : 1753,
          "y" : 64
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 1768,
          "y" : 101
        },
        "b" : {
          "x" : 1775,
          "y" : 105
        },
        "c" : {
          "x" : 1775,
          "y" : 97
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 1775,
          "y" : 97
        }
      }
    } ]
  }, {
    "id" : 75719,
    "reactomeId" : 29356,
    "displayName" : "H2O",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 1805,
      "y" : 268
    },
    "minX" : 1784,
    "maxX" : 1827,
    "minY" : 189,
    "maxY" : 282,
    "prop" : {
      "x" : 1784,
      "y" : 255,
      "width" : 42,
      "height" : 27
    },
    "textPosition" : {
      "x" : 1788,
      "y" : 258
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1821,
          "y" : 260
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1821,
          "y" : 260
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 75718,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1806,
          "y" : 252
        },
        "to" : {
          "x" : 1812,
          "y" : 189
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ],
    "trivial" : true
  }, {
    "id" : 75721,
    "reactomeId" : 10316881,
    "displayName" : "CDC42 GAPs",
    "schemaClass" : "CandidateSet",
    "renderableClass" : "EntitySet",
    "position" : {
      "x" : 1697,
      "y" : 291
    },
    "minX" : 1654,
    "maxX" : 1740,
    "minY" : 215,
    "maxY" : 303,
    "prop" : {
      "x" : 1654,
      "y" : 279,
      "width" : 86,
      "height" : 24
    },
    "textPosition" : {
      "x" : 1654,
      "y" : 280
    },
    "connectors" : [ {
      "edgeId" : 75718,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 1697,
          "y" : 273
        },
        "to" : {
          "x" : 1698,
          "y" : 223
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 1698,
          "y" : 219
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1698,
          "y" : 219
        }
      }
    } ]
  }, {
    "id" : 75720,
    "reactomeId" : 29372,
    "displayName" : "Pi",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 1541,
      "y" : 265
    },
    "minX" : 1526,
    "maxX" : 1577,
    "minY" : 198,
    "maxY" : 277,
    "prop" : {
      "x" : 1526,
      "y" : 253,
      "width" : 31,
      "height" : 24
    },
    "textPosition" : {
      "x" : 1532,
      "y" : 254
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1552,
          "y" : 258
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1552,
          "y" : 258
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 75718,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 1547,
          "y" : 250
        },
        "to" : {
          "x" : 1577,
          "y" : 198
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 1547,
          "y" : 242
        },
        "b" : {
          "x" : 1547,
          "y" : 250
        },
        "c" : {
          "x" : 1554,
          "y" : 246
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 1554,
          "y" : 246
        }
      }
    } ]
  }, {
    "id" : 75723,
    "reactomeId" : 10316860,
    "displayName" : "CDC42 GDIs",
    "schemaClass" : "DefinedSet",
    "renderableClass" : "EntitySet",
    "position" : {
      "x" : 1407,
      "y" : 129
    },
    "minX" : 1365,
    "maxX" : 1469,
    "minY" : 118,
    "maxY" : 174,
    "prop" : {
      "x" : 1365,
      "y" : 118,
      "width" : 84,
      "height" : 23
    },
    "textPosition" : {
      "x" : 1366,
      "y" : 119
    },
    "connectors" : [ {
      "edgeId" : 75722,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1422,
          "y" : 147
        },
        "to" : {
          "x" : 1469,
          "y" : 174
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 75724,
    "reactomeId" : 10316862,
    "displayName" : "CDC42:GDP:CDC42 GDIs",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 1463,
      "y" : 258
    },
    "minX" : 1421,
    "maxX" : 1512,
    "minY" : 233,
    "maxY" : 278,
    "prop" : {
      "x" : 1421,
      "y" : 239,
      "width" : 85,
      "height" : 39
    },
    "textPosition" : {
      "x" : 1422,
      "y" : 243
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1506,
          "y" : 239
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1506,
          "y" : 239
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 75722,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 75727,
    "reactomeId" : 10316850,
    "displayName" : "CDC42:GTP:CDC42 effectors",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 1947,
      "y" : 285
    },
    "minX" : 1893,
    "maxX" : 2008,
    "minY" : 261,
    "maxY" : 303,
    "prop" : {
      "x" : 1893,
      "y" : 267,
      "width" : 109,
      "height" : 36
    },
    "textPosition" : {
      "x" : 1893,
      "y" : 268
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 2002,
          "y" : 267
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 2002,
          "y" : 267
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 75725,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 75726,
    "reactomeId" : 10316848,
    "displayName" : "CDC42 effectors",
    "schemaClass" : "CandidateSet",
    "renderableClass" : "EntitySet",
    "position" : {
      "x" : 2016,
      "y" : 169
    },
    "minX" : 1942,
    "maxX" : 2050,
    "minY" : 138,
    "maxY" : 187,
    "prop" : {
      "x" : 1982,
      "y" : 152,
      "width" : 68,
      "height" : 35
    },
    "textPosition" : {
      "x" : 1984,
      "y" : 152
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 204
    },
    "fgColor" : {
      "r" : 0,
      "g" : 0,
      "b" : 0
    },
    "connectors" : [ {
      "edgeId" : 75725,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1976,
          "y" : 154
        },
        "to" : {
          "x" : 1942,
          "y" : 138
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 75729,
    "reactomeId" : 10317050,
    "displayName" : "RHOJ:GDP",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 3161,
      "y" : 952
    },
    "minX" : 2998,
    "maxX" : 3204,
    "minY" : 935,
    "maxY" : 1005,
    "prop" : {
      "x" : 3124,
      "y" : 941,
      "width" : 74,
      "height" : 23
    },
    "textPosition" : {
      "x" : 3127,
      "y" : 943
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 3198,
          "y" : 941
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 3198,
          "y" : 941
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 75728,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 3161,
          "y" : 967
        },
        "to" : {
          "x" : 3161,
          "y" : 1005
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 75734,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 3121,
          "y" : 955
        },
        "to" : {
          "x" : 2998,
          "y" : 969
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 3115,
          "y" : 960
        },
        "b" : {
          "x" : 3121,
          "y" : 955
        },
        "c" : {
          "x" : 3114,
          "y" : 952
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 3114,
          "y" : 952
        }
      }
    } ]
  }, {
    "id" : 75731,
    "reactomeId" : 10317048,
    "displayName" : "RHOJ:GTP",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 3158,
      "y" : 1136
    },
    "minX" : 2998,
    "maxX" : 3201,
    "minY" : 1079,
    "maxY" : 1148,
    "prop" : {
      "x" : 3122,
      "y" : 1124,
      "width" : 73,
      "height" : 24
    },
    "textPosition" : {
      "x" : 3126,
      "y" : 1127
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 3195,
          "y" : 1124
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 3195,
          "y" : 1124
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 75728,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 3158,
          "y" : 1121
        },
        "to" : {
          "x" : 3161,
          "y" : 1079
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 3155,
          "y" : 1114
        },
        "b" : {
          "x" : 3158,
          "y" : 1121
        },
        "c" : {
          "x" : 3162,
          "y" : 1114
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 3162,
          "y" : 1114
        }
      }
    }, {
      "edgeId" : 75734,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 3119,
          "y" : 1127
        },
        "to" : {
          "x" : 2998,
          "y" : 1099
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 75730,
    "reactomeId" : 29438,
    "displayName" : "GTP",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 3095,
      "y" : 985
    },
    "minX" : 3076,
    "maxX" : 3161,
    "minY" : 974,
    "maxY" : 1005,
    "prop" : {
      "x" : 3076,
      "y" : 975,
      "width" : 39,
      "height" : 20
    },
    "textPosition" : {
      "x" : 3079,
      "y" : 975
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 3110,
          "y" : 980
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 3110,
          "y" : 980
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 75728,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 3118,
          "y" : 990
        },
        "to" : {
          "x" : 3161,
          "y" : 1005
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 75733,
    "reactomeId" : 10317057,
    "displayName" : "RHOJ GEFs",
    "schemaClass" : "CandidateSet",
    "renderableClass" : "EntitySet",
    "position" : {
      "x" : 3075,
      "y" : 1037
    },
    "minX" : 3040,
    "maxX" : 3153,
    "minY" : 1026,
    "maxY" : 1048,
    "prop" : {
      "x" : 3040,
      "y" : 1026,
      "width" : 71,
      "height" : 22
    },
    "textPosition" : {
      "x" : 3055,
      "y" : 1020
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 204
    },
    "fgColor" : {
      "r" : 0,
      "g" : 0,
      "b" : 0
    },
    "connectors" : [ {
      "edgeId" : 75728,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 3117,
          "y" : 1035
        },
        "to" : {
          "x" : 3145,
          "y" : 1034
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 3149,
          "y" : 1034
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 3149,
          "y" : 1034
        }
      }
    } ]
  }, {
    "id" : 75732,
    "reactomeId" : 29420,
    "displayName" : "GDP",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 3099,
      "y" : 1087
    },
    "minX" : 3079,
    "maxX" : 3161,
    "minY" : 1074,
    "maxY" : 1099,
    "prop" : {
      "x" : 3079,
      "y" : 1075,
      "width" : 40,
      "height" : 24
    },
    "textPosition" : {
      "x" : 3082,
      "y" : 1076
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 3114,
          "y" : 1080
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 3114,
          "y" : 1080
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 75728,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 3122,
          "y" : 1084
        },
        "to" : {
          "x" : 3161,
          "y" : 1079
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 3128,
          "y" : 1079
        },
        "b" : {
          "x" : 3122,
          "y" : 1084
        },
        "c" : {
          "x" : 3129,
          "y" : 1087
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 3129,
          "y" : 1087
        }
      }
    } ]
  }, {
    "id" : 75735,
    "reactomeId" : 29356,
    "displayName" : "H2O",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 2946,
      "y" : 1128
    },
    "minX" : 2926,
    "maxX" : 2998,
    "minY" : 1099,
    "maxY" : 1138,
    "prop" : {
      "x" : 2926,
      "y" : 1118,
      "width" : 40,
      "height" : 20
    },
    "textPosition" : {
      "x" : 2929,
      "y" : 1118
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 2961,
          "y" : 1123
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 2961,
          "y" : 1123
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 75734,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 2963,
          "y" : 1115
        },
        "to" : {
          "x" : 2998,
          "y" : 1099
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ],
    "trivial" : true
  }, {
    "id" : 75737,
    "reactomeId" : 10317052,
    "displayName" : "RHOJ GAPs",
    "schemaClass" : "CandidateSet",
    "renderableClass" : "EntitySet",
    "position" : {
      "x" : 2884,
      "y" : 1031
    },
    "minX" : 2848,
    "maxX" : 2988,
    "minY" : 1020,
    "maxY" : 1042,
    "prop" : {
      "x" : 2848,
      "y" : 1020,
      "width" : 73,
      "height" : 22
    },
    "textPosition" : {
      "x" : 2848,
      "y" : 1020
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 204
    },
    "fgColor" : {
      "r" : 0,
      "g" : 0,
      "b" : 0
    },
    "connectors" : [ {
      "edgeId" : 75734,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 2927,
          "y" : 1031
        },
        "to" : {
          "x" : 2980,
          "y" : 1032
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 2984,
          "y" : 1032
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 2984,
          "y" : 1032
        }
      }
    } ]
  }, {
    "id" : 75736,
    "reactomeId" : 29372,
    "displayName" : "Pi",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 2948,
      "y" : 955
    },
    "minX" : 2933,
    "maxX" : 2998,
    "minY" : 942,
    "maxY" : 969,
    "prop" : {
      "x" : 2933,
      "y" : 943,
      "width" : 31,
      "height" : 24
    },
    "textPosition" : {
      "x" : 2939,
      "y" : 944
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 2959,
          "y" : 948
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 2959,
          "y" : 948
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 75734,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 2967,
          "y" : 959
        },
        "to" : {
          "x" : 2998,
          "y" : 969
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 2975,
          "y" : 957
        },
        "b" : {
          "x" : 2967,
          "y" : 959
        },
        "c" : {
          "x" : 2972,
          "y" : 965
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 2972,
          "y" : 965
        }
      }
    } ]
  }, {
    "id" : 75739,
    "reactomeId" : 10317088,
    "displayName" : "RHOQ:GDP",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 3156,
      "y" : 1338
    },
    "minX" : 2976,
    "maxX" : 3199,
    "minY" : 1321,
    "maxY" : 1421,
    "prop" : {
      "x" : 3120,
      "y" : 1327,
      "width" : 73,
      "height" : 22
    },
    "textPosition" : {
      "x" : 3120,
      "y" : 1328
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 3193,
          "y" : 1327
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 3193,
          "y" : 1327
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 75738,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 3156,
          "y" : 1352
        },
        "to" : {
          "x" : 3158,
          "y" : 1421
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 75744,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 3117,
          "y" : 1342
        },
        "to" : {
          "x" : 2976,
          "y" : 1360
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 3111,
          "y" : 1347
        },
        "b" : {
          "x" : 3117,
          "y" : 1342
        },
        "c" : {
          "x" : 3110,
          "y" : 1339
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 3110,
          "y" : 1339
        }
      }
    } ]
  }, {
    "id" : 75741,
    "reactomeId" : 10290571,
    "displayName" : "RHOQ:GTP",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 3159,
      "y" : 1570
    },
    "minX" : 2980,
    "maxX" : 3201,
    "minY" : 1513,
    "maxY" : 1653,
    "prop" : {
      "x" : 3123,
      "y" : 1559,
      "width" : 72,
      "height" : 22
    },
    "textPosition" : {
      "x" : 3123,
      "y" : 1560
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 3195,
          "y" : 1559
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 3195,
          "y" : 1559
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 75738,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 3158,
          "y" : 1556
        },
        "to" : {
          "x" : 3158,
          "y" : 1513
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 3154,
          "y" : 1549
        },
        "b" : {
          "x" : 3158,
          "y" : 1556
        },
        "c" : {
          "x" : 3162,
          "y" : 1549
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 3162,
          "y" : 1549
        }
      }
    }, {
      "edgeId" : 75744,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 3120,
          "y" : 1568
        },
        "to" : {
          "x" : 2980,
          "y" : 1561
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 75748,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 3156,
          "y" : 1584
        },
        "to" : {
          "x" : 3137,
          "y" : 1653
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 75751,
      "type" : "INPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 75740,
    "reactomeId" : 29438,
    "displayName" : "GTP",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 3093,
      "y" : 1411
    },
    "minX" : 3073,
    "maxX" : 3158,
    "minY" : 1395,
    "maxY" : 1426,
    "prop" : {
      "x" : 3073,
      "y" : 1396,
      "width" : 41,
      "height" : 30
    },
    "textPosition" : {
      "x" : 3077,
      "y" : 1400
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 3109,
          "y" : 1401
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 3109,
          "y" : 1401
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 75738,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 3117,
          "y" : 1414
        },
        "to" : {
          "x" : 3158,
          "y" : 1421
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 75743,
    "reactomeId" : 10317105,
    "displayName" : "RHOQ GEFs",
    "schemaClass" : "DefinedSet",
    "renderableClass" : "EntitySet",
    "position" : {
      "x" : 3040,
      "y" : 1462
    },
    "minX" : 3002,
    "maxX" : 3151,
    "minY" : 1451,
    "maxY" : 1473,
    "prop" : {
      "x" : 3002,
      "y" : 1451,
      "width" : 76,
      "height" : 22
    },
    "textPosition" : {
      "x" : 3016,
      "y" : 1445
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 204
    },
    "fgColor" : {
      "r" : 0,
      "g" : 0,
      "b" : 0
    },
    "connectors" : [ {
      "edgeId" : 75738,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 3084,
          "y" : 1463
        },
        "to" : {
          "x" : 3143,
          "y" : 1466
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 3147,
          "y" : 1466
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 3147,
          "y" : 1466
        }
      }
    } ]
  }, {
    "id" : 75742,
    "reactomeId" : 29420,
    "displayName" : "GDP",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 3083,
      "y" : 1526
    },
    "minX" : 3062,
    "maxX" : 3158,
    "minY" : 1510,
    "maxY" : 1541,
    "prop" : {
      "x" : 3062,
      "y" : 1511,
      "width" : 42,
      "height" : 30
    },
    "textPosition" : {
      "x" : 3066,
      "y" : 1515
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 3099,
          "y" : 1516
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 3099,
          "y" : 1516
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 75738,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 3107,
          "y" : 1522
        },
        "to" : {
          "x" : 3158,
          "y" : 1513
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 3113,
          "y" : 1517
        },
        "b" : {
          "x" : 3107,
          "y" : 1522
        },
        "c" : {
          "x" : 3115,
          "y" : 1525
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 3115,
          "y" : 1525
        }
      }
    } ]
  }, {
    "id" : 75745,
    "reactomeId" : 29356,
    "displayName" : "H2O",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 2885,
      "y" : 1558
    },
    "minX" : 2863,
    "maxX" : 2980,
    "minY" : 1543,
    "maxY" : 1572,
    "prop" : {
      "x" : 2863,
      "y" : 1544,
      "width" : 44,
      "height" : 28
    },
    "textPosition" : {
      "x" : 2868,
      "y" : 1547
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 2902,
          "y" : 1549
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 2902,
          "y" : 1549
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 75744,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 2910,
          "y" : 1558
        },
        "to" : {
          "x" : 2980,
          "y" : 1561
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ],
    "trivial" : true
  }, {
    "id" : 75747,
    "reactomeId" : 10317090,
    "displayName" : "RHOQ GAPs",
    "schemaClass" : "CandidateSet",
    "renderableClass" : "EntitySet",
    "position" : {
      "x" : 2870,
      "y" : 1469
    },
    "minX" : 2831,
    "maxX" : 2966,
    "minY" : 1458,
    "maxY" : 1480,
    "prop" : {
      "x" : 2831,
      "y" : 1458,
      "width" : 78,
      "height" : 22
    },
    "textPosition" : {
      "x" : 2846,
      "y" : 1452
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 204
    },
    "fgColor" : {
      "r" : 0,
      "g" : 0,
      "b" : 0
    },
    "connectors" : [ {
      "edgeId" : 75744,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 2915,
          "y" : 1469
        },
        "to" : {
          "x" : 2958,
          "y" : 1470
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 2962,
          "y" : 1471
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 2962,
          "y" : 1471
        }
      }
    } ]
  }, {
    "id" : 75746,
    "reactomeId" : 29372,
    "displayName" : "Pi",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 2908,
      "y" : 1339
    },
    "minX" : 2890,
    "maxX" : 2976,
    "minY" : 1326,
    "maxY" : 1360,
    "prop" : {
      "x" : 2890,
      "y" : 1327,
      "width" : 36,
      "height" : 25
    },
    "textPosition" : {
      "x" : 2898,
      "y" : 1329
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 2921,
          "y" : 1332
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 2921,
          "y" : 1332
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 75744,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 2929,
          "y" : 1344
        },
        "to" : {
          "x" : 2976,
          "y" : 1360
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 2937,
          "y" : 1342
        },
        "b" : {
          "x" : 2929,
          "y" : 1344
        },
        "c" : {
          "x" : 2934,
          "y" : 1350
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 2934,
          "y" : 1350
        }
      }
    } ]
  }, {
    "id" : 75749,
    "reactomeId" : 10317099,
    "displayName" : "RHOQ effectors",
    "schemaClass" : "CandidateSet",
    "renderableClass" : "EntitySet",
    "position" : {
      "x" : 3056,
      "y" : 1598
    },
    "minX" : 3007,
    "maxX" : 3137,
    "minY" : 1587,
    "maxY" : 1653,
    "prop" : {
      "x" : 3007,
      "y" : 1587,
      "width" : 98,
      "height" : 22
    },
    "textPosition" : {
      "x" : 3024,
      "y" : 1581
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 204
    },
    "fgColor" : {
      "r" : 0,
      "g" : 0,
      "b" : 0
    },
    "connectors" : [ {
      "edgeId" : 75748,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 3072,
          "y" : 1615
        },
        "to" : {
          "x" : 3137,
          "y" : 1653
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 75750,
    "reactomeId" : 10317101,
    "displayName" : "RHOQ:GTP:RHOQ effectors",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 3174,
      "y" : 1777
    },
    "minX" : 3125,
    "maxX" : 3230,
    "minY" : 1752,
    "maxY" : 1796,
    "prop" : {
      "x" : 3125,
      "y" : 1758,
      "width" : 99,
      "height" : 38
    },
    "textPosition" : {
      "x" : 3137,
      "y" : 1747
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 3224,
          "y" : 1758
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 3224,
          "y" : 1758
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 75748,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 75752,
    "reactomeId" : 10290565,
    "displayName" : "RHOQ:GTP",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 2689,
      "y" : 1491
    },
    "minX" : 2597,
    "maxX" : 2731,
    "minY" : 1449,
    "maxY" : 1502,
    "prop" : {
      "x" : 2653,
      "y" : 1480,
      "width" : 72,
      "height" : 22
    },
    "textPosition" : {
      "x" : 2653,
      "y" : 1481
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 2725,
          "y" : 1480
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 2725,
          "y" : 1480
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 75751,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 75753,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 2664,
          "y" : 1477
        },
        "to" : {
          "x" : 2597,
          "y" : 1449
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 75755,
    "reactomeId" : 10290567,
    "displayName" : "RHOQ:GTP:GOPC:CFTR",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 2687,
      "y" : 1383
    },
    "minX" : 2646,
    "maxX" : 2734,
    "minY" : 1359,
    "maxY" : 1402,
    "prop" : {
      "x" : 2646,
      "y" : 1365,
      "width" : 82,
      "height" : 37
    },
    "textPosition" : {
      "x" : 2649,
      "y" : 1367
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 2728,
          "y" : 1365
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 2728,
          "y" : 1365
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 75753,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 75754,
    "reactomeId" : 10290559,
    "displayName" : "GOPC:CFTR",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 2568,
      "y" : 1398
    },
    "minX" : 2530,
    "maxX" : 2612,
    "minY" : 1381,
    "maxY" : 1449,
    "prop" : {
      "x" : 2530,
      "y" : 1387,
      "width" : 76,
      "height" : 22
    },
    "textPosition" : {
      "x" : 2530,
      "y" : 1388
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 2606,
          "y" : 1387
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 2606,
          "y" : 1387
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 75753,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 2574,
          "y" : 1412
        },
        "to" : {
          "x" : 2597,
          "y" : 1449
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 75757,
    "reactomeId" : 10317112,
    "displayName" : "RHOH",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 3176,
      "y" : 1886
    },
    "minX" : 3154,
    "maxX" : 3204,
    "minY" : 1869,
    "maxY" : 1932,
    "prop" : {
      "x" : 3154,
      "y" : 1875,
      "width" : 44,
      "height" : 22
    },
    "textPosition" : {
      "x" : 3154,
      "y" : 1875
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 3198,
          "y" : 1875
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 3198,
          "y" : 1875
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 75756,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 3176,
          "y" : 1900
        },
        "to" : {
          "x" : 3178,
          "y" : 1932
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 75759,
    "reactomeId" : 10317114,
    "displayName" : "RHOH:GTP",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 3183,
      "y" : 2042
    },
    "minX" : 3111,
    "maxX" : 3225,
    "minY" : 1996,
    "maxY" : 2105,
    "prop" : {
      "x" : 3147,
      "y" : 2031,
      "width" : 72,
      "height" : 22
    },
    "textPosition" : {
      "x" : 3147,
      "y" : 2032
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 3219,
          "y" : 2031
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 3219,
          "y" : 2031
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 75857,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 3165,
          "y" : 2028
        },
        "to" : {
          "x" : 3111,
          "y" : 1996
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 75756,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 75760,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 3183,
          "y" : 2056
        },
        "to" : {
          "x" : 3185,
          "y" : 2105
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 75758,
    "reactomeId" : 29438,
    "displayName" : "GTP",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 3117,
      "y" : 1938
    },
    "minX" : 3099,
    "maxX" : 3178,
    "minY" : 1924,
    "maxY" : 1951,
    "prop" : {
      "x" : 3099,
      "y" : 1925,
      "width" : 36,
      "height" : 26
    },
    "textPosition" : {
      "x" : 3101,
      "y" : 1927
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 3130,
          "y" : 1930
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 3130,
          "y" : 1930
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 75756,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 3138,
          "y" : 1936
        },
        "to" : {
          "x" : 3178,
          "y" : 1932
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 75761,
    "reactomeId" : 10317152,
    "displayName" : "RHOH effectors",
    "schemaClass" : "CandidateSet",
    "renderableClass" : "EntitySet",
    "position" : {
      "x" : 3092,
      "y" : 2097
    },
    "minX" : 3043,
    "maxX" : 3185,
    "minY" : 2086,
    "maxY" : 2108,
    "prop" : {
      "x" : 3043,
      "y" : 2086,
      "width" : 98,
      "height" : 22
    },
    "textPosition" : {
      "x" : 3060,
      "y" : 2080
    },
    "connectors" : [ {
      "edgeId" : 75760,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 3147,
          "y" : 2101
        },
        "to" : {
          "x" : 3185,
          "y" : 2105
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 75762,
    "reactomeId" : 10317154,
    "displayName" : "RHOH:GTP:RHOH effectors",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 3185,
      "y" : 2213
    },
    "minX" : 3134,
    "maxX" : 3242,
    "minY" : 2190,
    "maxY" : 2231,
    "prop" : {
      "x" : 3134,
      "y" : 2196,
      "width" : 102,
      "height" : 35
    },
    "textPosition" : {
      "x" : 3147,
      "y" : 2182
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 3236,
          "y" : 2196
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 3236,
          "y" : 2196
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 75760,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 75765,
    "reactomeId" : 29438,
    "displayName" : "GTP",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 1313,
      "y" : 2371
    },
    "minX" : 1290,
    "maxX" : 1335,
    "minY" : 2355,
    "maxY" : 2410,
    "prop" : {
      "x" : 1293,
      "y" : 2356,
      "width" : 41,
      "height" : 30
    },
    "textPosition" : {
      "x" : 1297,
      "y" : 2360
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1329,
          "y" : 2361
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1329,
          "y" : 2361
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 75763,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1304,
          "y" : 2389
        },
        "to" : {
          "x" : 1290,
          "y" : 2410
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 75764,
    "reactomeId" : 10317186,
    "displayName" : "RHOU:GDP",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 1411,
      "y" : 2412
    },
    "minX" : 1244,
    "maxX" : 1453,
    "minY" : 2395,
    "maxY" : 2445,
    "prop" : {
      "x" : 1375,
      "y" : 2401,
      "width" : 72,
      "height" : 22
    },
    "textPosition" : {
      "x" : 1387,
      "y" : 2388
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1447,
          "y" : 2401
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1447,
          "y" : 2401
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 75763,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1372,
          "y" : 2411
        },
        "to" : {
          "x" : 1290,
          "y" : 2410
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 75763,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 1372,
          "y" : 2419
        },
        "to" : {
          "x" : 1258,
          "y" : 2445
        }
      }, {
        "from" : {
          "x" : 1258,
          "y" : 2445
        },
        "to" : {
          "x" : 1250,
          "y" : 2424
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 1248,
          "y" : 2420
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1248,
          "y" : 2420
        }
      }
    } ]
  }, {
    "id" : 75767,
    "reactomeId" : 29420,
    "displayName" : "GDP",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 1161,
      "y" : 2356
    },
    "minX" : 1141,
    "maxX" : 1197,
    "minY" : 2340,
    "maxY" : 2410,
    "prop" : {
      "x" : 1141,
      "y" : 2341,
      "width" : 41,
      "height" : 30
    },
    "textPosition" : {
      "x" : 1144,
      "y" : 2345
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1177,
          "y" : 2346
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1177,
          "y" : 2346
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 75763,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 1171,
          "y" : 2374
        },
        "to" : {
          "x" : 1197,
          "y" : 2410
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 1178,
          "y" : 2377
        },
        "b" : {
          "x" : 1171,
          "y" : 2374
        },
        "c" : {
          "x" : 1172,
          "y" : 2382
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 1172,
          "y" : 2382
        }
      }
    } ]
  }, {
    "id" : 75766,
    "reactomeId" : 10317162,
    "displayName" : "RHOU:GTP",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 1112,
      "y" : 2411
    },
    "minX" : 1063,
    "maxX" : 1197,
    "minY" : 2347,
    "maxY" : 2422,
    "prop" : {
      "x" : 1077,
      "y" : 2400,
      "width" : 71,
      "height" : 22
    },
    "textPosition" : {
      "x" : 1077,
      "y" : 2401
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1148,
          "y" : 2400
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1148,
          "y" : 2400
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 75763,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 1151,
          "y" : 2410
        },
        "to" : {
          "x" : 1197,
          "y" : 2410
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 1158,
          "y" : 2406
        },
        "b" : {
          "x" : 1151,
          "y" : 2410
        },
        "c" : {
          "x" : 1158,
          "y" : 2414
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 1158,
          "y" : 2414
        }
      }
    }, {
      "edgeId" : 75768,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1103,
          "y" : 2397
        },
        "to" : {
          "x" : 1063,
          "y" : 2347
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 75769,
    "reactomeId" : 10317180,
    "displayName" : "RHOU effectors",
    "schemaClass" : "CandidateSet",
    "renderableClass" : "EntitySet",
    "position" : {
      "x" : 1047,
      "y" : 2301
    },
    "minX" : 999,
    "maxX" : 1096,
    "minY" : 2290,
    "maxY" : 2347,
    "prop" : {
      "x" : 999,
      "y" : 2290,
      "width" : 97,
      "height" : 22
    },
    "textPosition" : {
      "x" : 1015,
      "y" : 2284
    },
    "connectors" : [ {
      "edgeId" : 75768,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1050,
          "y" : 2318
        },
        "to" : {
          "x" : 1063,
          "y" : 2347
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 75770,
    "reactomeId" : 10317182,
    "displayName" : "RHOU:GTP:RHOU effectors",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 997,
      "y" : 2419
    },
    "minX" : 946,
    "maxX" : 1054,
    "minY" : 2395,
    "maxY" : 2437,
    "prop" : {
      "x" : 946,
      "y" : 2401,
      "width" : 102,
      "height" : 36
    },
    "textPosition" : {
      "x" : 959,
      "y" : 2388
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1048,
          "y" : 2401
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1048,
          "y" : 2401
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 75768,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 75773,
    "reactomeId" : 29438,
    "displayName" : "GTP",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 2614,
      "y" : 119
    },
    "minX" : 2594,
    "maxX" : 2645,
    "minY" : 68,
    "maxY" : 134,
    "prop" : {
      "x" : 2594,
      "y" : 104,
      "width" : 41,
      "height" : 30
    },
    "textPosition" : {
      "x" : 2598,
      "y" : 108
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 2630,
          "y" : 109
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 2630,
          "y" : 109
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 75771,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 2623,
          "y" : 101
        },
        "to" : {
          "x" : 2645,
          "y" : 68
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 75772,
    "reactomeId" : 10316913,
    "displayName" : "RAC2:GDP",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 2570,
      "y" : 59
    },
    "minX" : 2535,
    "maxX" : 2645,
    "minY" : 42,
    "maxY" : 216,
    "prop" : {
      "x" : 2535,
      "y" : 48,
      "width" : 70,
      "height" : 22
    },
    "textPosition" : {
      "x" : 2535,
      "y" : 49
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 2605,
          "y" : 48
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 2605,
          "y" : 48
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 75777,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 2571,
          "y" : 73
        },
        "to" : {
          "x" : 2588,
          "y" : 216
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 2576,
          "y" : 79
        },
        "b" : {
          "x" : 2571,
          "y" : 73
        },
        "c" : {
          "x" : 2568,
          "y" : 80
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 2568,
          "y" : 80
        }
      }
    }, {
      "edgeId" : 75781,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 2564,
          "y" : 73
        },
        "to" : {
          "x" : 2543,
          "y" : 113
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 75771,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 2608,
          "y" : 63
        },
        "to" : {
          "x" : 2645,
          "y" : 68
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 75775,
    "reactomeId" : 29420,
    "displayName" : "GDP",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 2736,
      "y" : 118
    },
    "minX" : 2708,
    "maxX" : 2758,
    "minY" : 69,
    "maxY" : 133,
    "prop" : {
      "x" : 2715,
      "y" : 103,
      "width" : 42,
      "height" : 30
    },
    "textPosition" : {
      "x" : 2719,
      "y" : 107
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 2752,
          "y" : 108
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 2752,
          "y" : 108
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 75771,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 2727,
          "y" : 100
        },
        "to" : {
          "x" : 2708,
          "y" : 69
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 2720,
          "y" : 96
        },
        "b" : {
          "x" : 2727,
          "y" : 100
        },
        "c" : {
          "x" : 2727,
          "y" : 92
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 2727,
          "y" : 92
        }
      }
    } ]
  }, {
    "id" : 75774,
    "reactomeId" : 10234765,
    "displayName" : "RAC2:GTP",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 2773,
      "y" : 67
    },
    "minX" : 2708,
    "maxX" : 2922,
    "minY" : 50,
    "maxY" : 202,
    "prop" : {
      "x" : 2739,
      "y" : 56,
      "width" : 69,
      "height" : 22
    },
    "textPosition" : {
      "x" : 2739,
      "y" : 57
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 2808,
          "y" : 56
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 2808,
          "y" : 56
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 75777,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 2773,
          "y" : 81
        },
        "to" : {
          "x" : 2773,
          "y" : 202
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 75784,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 2799,
          "y" : 81
        },
        "to" : {
          "x" : 2922,
          "y" : 128
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 75787,
      "type" : "INPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 75881,
      "type" : "INPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 75886,
      "type" : "INPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 75771,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 2736,
          "y" : 68
        },
        "to" : {
          "x" : 2708,
          "y" : 69
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 2729,
          "y" : 72
        },
        "b" : {
          "x" : 2736,
          "y" : 68
        },
        "c" : {
          "x" : 2729,
          "y" : 64
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 2729,
          "y" : 64
        }
      }
    } ]
  } ],
  "edges" : [ {
    "id" : 75777,
    "reactomeId" : 10316932,
    "displayName" : "RAC2 GAPs stimulate RAC2 GTPase activity",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 2686,
      "y" : 221
    },
    "minX" : 2588,
    "maxX" : 2773,
    "minY" : 202,
    "maxY" : 227,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 2773,
        "y" : 202
      },
      "to" : {
        "x" : 2686,
        "y" : 221
      }
    }, {
      "from" : {
        "x" : 2686,
        "y" : 221
      },
      "to" : {
        "x" : 2588,
        "y" : 216
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 2680,
        "y" : 215
      },
      "b" : {
        "x" : 2692,
        "y" : 227
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 2686,
        "y" : 221
      }
    },
    "inputs" : [ {
      "id" : 75778,
      "points" : [ {
        "x" : 2770,
        "y" : 246
      } ]
    }, {
      "id" : 75774,
      "points" : [ {
        "x" : 2773,
        "y" : 81
      } ]
    } ],
    "outputs" : [ {
      "id" : 75772,
      "points" : [ {
        "x" : 2571,
        "y" : 73
      } ]
    }, {
      "id" : 75779,
      "points" : [ {
        "x" : 2562,
        "y" : 241
      } ]
    } ],
    "catalysts" : [ {
      "id" : 75780,
      "points" : [ {
        "x" : 2685,
        "y" : 290
      } ]
    } ]
  }, {
    "id" : 75781,
    "reactomeId" : 10316919,
    "displayName" : "RAC2 GDIs block activation of RAC2",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 2523,
      "y" : 154
    },
    "minX" : 2517,
    "maxX" : 2543,
    "minY" : 113,
    "maxY" : 176,
    "reactionType" : "binding",
    "segments" : [ {
      "from" : {
        "x" : 2543,
        "y" : 113
      },
      "to" : {
        "x" : 2523,
        "y" : 154
      }
    }, {
      "from" : {
        "x" : 2523,
        "y" : 154
      },
      "to" : {
        "x" : 2525,
        "y" : 176
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 2520,
        "y" : 169
      },
      "b" : {
        "x" : 2525,
        "y" : 176
      },
      "c" : {
        "x" : 2528,
        "y" : 169
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 2528,
        "y" : 169
      }
    },
    "reactionShape" : {
      "c" : {
        "x" : 2523,
        "y" : 154
      },
      "r" : 5,
      "type" : "CIRCLE",
      "centre" : {
        "x" : 2523,
        "y" : 154
      }
    },
    "inputs" : [ {
      "id" : 75782,
      "points" : [ {
        "x" : 2511,
        "y" : 116
      } ]
    }, {
      "id" : 75772,
      "points" : [ {
        "x" : 2564,
        "y" : 73
      } ]
    } ],
    "outputs" : [ {
      "id" : 75783
    } ]
  }, {
    "id" : 75784,
    "reactomeId" : 10316927,
    "displayName" : "RAC2 binds effectors at the plasma membrane",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 2952,
      "y" : 126
    },
    "minX" : 2922,
    "maxX" : 3003,
    "minY" : 88,
    "maxY" : 132,
    "reactionType" : "binding",
    "segments" : [ {
      "from" : {
        "x" : 2922,
        "y" : 128
      },
      "to" : {
        "x" : 2952,
        "y" : 126
      }
    }, {
      "from" : {
        "x" : 2952,
        "y" : 126
      },
      "to" : {
        "x" : 3003,
        "y" : 88
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 3000,
        "y" : 95
      },
      "b" : {
        "x" : 3003,
        "y" : 88
      },
      "c" : {
        "x" : 2995,
        "y" : 89
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 2995,
        "y" : 89
      }
    },
    "reactionShape" : {
      "c" : {
        "x" : 2952,
        "y" : 126
      },
      "r" : 5,
      "type" : "CIRCLE",
      "centre" : {
        "x" : 2952,
        "y" : 126
      }
    },
    "inputs" : [ {
      "id" : 75774,
      "points" : [ {
        "x" : 2799,
        "y" : 81
      } ]
    }, {
      "id" : 75785,
      "points" : [ {
        "x" : 2906,
        "y" : 153
      } ]
    } ],
    "outputs" : [ {
      "id" : 75786
    } ]
  }, {
    "id" : 75787,
    "reactomeId" : 10316939,
    "displayName" : "RAC2 translocates to the phagocytic vesicle membrane",
    "schemaClass" : "BlackBoxEvent",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 2857,
      "y" : 269
    },
    "minX" : 2765,
    "maxX" : 2863,
    "minY" : 81,
    "maxY" : 417,
    "reactionType" : "omitted",
    "segments" : [ {
      "from" : {
        "x" : 2777,
        "y" : 81
      },
      "to" : {
        "x" : 2857,
        "y" : 269
      }
    }, {
      "from" : {
        "x" : 2857,
        "y" : 269
      },
      "to" : {
        "x" : 2765,
        "y" : 417
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 2765,
        "y" : 409
      },
      "b" : {
        "x" : 2765,
        "y" : 417
      },
      "c" : {
        "x" : 2772,
        "y" : 413
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 2772,
        "y" : 413
      }
    },
    "reactionShape" : {
      "a" : {
        "x" : 2851,
        "y" : 263
      },
      "b" : {
        "x" : 2863,
        "y" : 275
      },
      "s" : "\\\\",
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 2857,
        "y" : 269
      }
    },
    "inputs" : [ {
      "id" : 75774
    } ],
    "outputs" : [ {
      "id" : 75788
    } ]
  }, {
    "id" : 75789,
    "reactomeId" : 10316941,
    "displayName" : "RAC2 binds effectors at the phagocytic vesicle membrane",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 2868,
      "y" : 470
    },
    "minX" : 2846,
    "maxX" : 2893,
    "minY" : 457,
    "maxY" : 500,
    "reactionType" : "binding",
    "segments" : [ {
      "from" : {
        "x" : 2846,
        "y" : 457
      },
      "to" : {
        "x" : 2868,
        "y" : 470
      }
    }, {
      "from" : {
        "x" : 2868,
        "y" : 470
      },
      "to" : {
        "x" : 2893,
        "y" : 500
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 2885,
        "y" : 497
      },
      "b" : {
        "x" : 2893,
        "y" : 500
      },
      "c" : {
        "x" : 2892,
        "y" : 492
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 2892,
        "y" : 492
      }
    },
    "reactionShape" : {
      "c" : {
        "x" : 2868,
        "y" : 470
      },
      "r" : 5,
      "type" : "CIRCLE",
      "centre" : {
        "x" : 2868,
        "y" : 470
      }
    },
    "inputs" : [ {
      "id" : 75790,
      "points" : [ {
        "x" : 2859,
        "y" : 436
      } ]
    }, {
      "id" : 75788,
      "points" : [ {
        "x" : 2797,
        "y" : 441
      } ]
    } ],
    "outputs" : [ {
      "id" : 75791
    } ]
  }, {
    "id" : 75660,
    "reactomeId" : 10315099,
    "displayName" : "RHOA GEFs activate RHOA",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 525,
      "y" : 65
    },
    "minX" : 484,
    "maxX" : 564,
    "minY" : 59,
    "maxY" : 71,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 484,
        "y" : 62
      },
      "to" : {
        "x" : 525,
        "y" : 65
      }
    }, {
      "from" : {
        "x" : 525,
        "y" : 65
      },
      "to" : {
        "x" : 564,
        "y" : 64
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 519,
        "y" : 59
      },
      "b" : {
        "x" : 531,
        "y" : 71
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 525,
        "y" : 65
      }
    },
    "inputs" : [ {
      "id" : 75661,
      "points" : [ {
        "x" : 454,
        "y" : 85
      } ]
    }, {
      "id" : 75662,
      "points" : [ {
        "x" : 419,
        "y" : 63
      } ]
    } ],
    "outputs" : [ {
      "id" : 75663,
      "points" : [ {
        "x" : 578,
        "y" : 98
      } ]
    }, {
      "id" : 75664,
      "points" : [ {
        "x" : 605,
        "y" : 64
      } ]
    } ],
    "catalysts" : [ {
      "id" : 75665,
      "points" : [ {
        "x" : 524,
        "y" : 136
      } ]
    } ]
  }, {
    "id" : 75792,
    "reactomeId" : 10316948,
    "displayName" : "RHOG GEFs activate RHOG",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 49,
      "y" : 481
    },
    "minX" : 43,
    "maxX" : 55,
    "minY" : 432,
    "maxY" : 518,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 48,
        "y" : 432
      },
      "to" : {
        "x" : 49,
        "y" : 481
      }
    }, {
      "from" : {
        "x" : 49,
        "y" : 481
      },
      "to" : {
        "x" : 51,
        "y" : 518
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 43,
        "y" : 475
      },
      "b" : {
        "x" : 55,
        "y" : 487
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 49,
        "y" : 481
      }
    },
    "inputs" : [ {
      "id" : 75793,
      "points" : [ {
        "x" : 51,
        "y" : 401
      } ]
    }, {
      "id" : 75794,
      "points" : [ {
        "x" : 98,
        "y" : 426
      } ]
    } ],
    "outputs" : [ {
      "id" : 75795,
      "points" : [ {
        "x" : 46,
        "y" : 550
      } ]
    }, {
      "id" : 75796,
      "points" : [ {
        "x" : 93,
        "y" : 525
      } ]
    } ],
    "catalysts" : [ {
      "id" : 75797,
      "points" : [ {
        "x" : 113,
        "y" : 476
      } ]
    } ]
  }, {
    "id" : 75666,
    "reactomeId" : 10315299,
    "displayName" : "RHOA GAPs stimulate RHOA GTPase activity",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 526,
      "y" : 216
    },
    "minX" : 421,
    "maxX" : 592,
    "minY" : 210,
    "maxY" : 222,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 592,
        "y" : 212
      },
      "to" : {
        "x" : 526,
        "y" : 216
      }
    }, {
      "from" : {
        "x" : 526,
        "y" : 216
      },
      "to" : {
        "x" : 421,
        "y" : 211
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 520,
        "y" : 210
      },
      "b" : {
        "x" : 532,
        "y" : 222
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 526,
        "y" : 216
      }
    },
    "inputs" : [ {
      "id" : 75667,
      "points" : [ {
        "x" : 604,
        "y" : 232
      } ]
    }, {
      "id" : 75664,
      "points" : [ {
        "x" : 639,
        "y" : 79
      } ]
    } ],
    "outputs" : [ {
      "id" : 75662,
      "points" : [ {
        "x" : 383,
        "y" : 78
      } ]
    }, {
      "id" : 75668,
      "points" : [ {
        "x" : 407,
        "y" : 241
      } ]
    } ],
    "catalysts" : [ {
      "id" : 75669,
      "points" : [ {
        "x" : 525,
        "y" : 262
      } ]
    } ]
  }, {
    "id" : 75798,
    "reactomeId" : 10316953,
    "displayName" : "RHOG GAPs stimulate RHOG GTPase activity",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 218,
      "y" : 475
    },
    "minX" : 212,
    "maxX" : 231,
    "minY" : 400,
    "maxY" : 556,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 215,
        "y" : 556
      },
      "to" : {
        "x" : 218,
        "y" : 475
      }
    }, {
      "from" : {
        "x" : 218,
        "y" : 475
      },
      "to" : {
        "x" : 231,
        "y" : 400
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 212,
        "y" : 469
      },
      "b" : {
        "x" : 224,
        "y" : 481
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 218,
        "y" : 475
      }
    },
    "inputs" : [ {
      "id" : 75795,
      "points" : [ {
        "x" : 84,
        "y" : 562
      } ]
    }, {
      "id" : 75799,
      "points" : [ {
        "x" : 253,
        "y" : 580
      } ]
    } ],
    "outputs" : [ {
      "id" : 75668,
      "points" : [ {
        "x" : 388,
        "y" : 271
      } ]
    }, {
      "id" : 75793,
      "points" : [ {
        "x" : 93,
        "y" : 389
      } ]
    } ],
    "catalysts" : [ {
      "id" : 75800,
      "points" : [ {
        "x" : 275,
        "y" : 469
      } ]
    } ]
  }, {
    "id" : 75670,
    "reactomeId" : 10316538,
    "displayName" : "GDIs block activation of RHOA",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 287,
      "y" : 174
    },
    "minX" : 272,
    "maxX" : 303,
    "minY" : 114,
    "maxY" : 239,
    "reactionType" : "binding",
    "segments" : [ {
      "from" : {
        "x" : 303,
        "y" : 114
      },
      "to" : {
        "x" : 287,
        "y" : 174
      }
    }, {
      "from" : {
        "x" : 287,
        "y" : 174
      },
      "to" : {
        "x" : 272,
        "y" : 239
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 270,
        "y" : 231
      },
      "b" : {
        "x" : 272,
        "y" : 239
      },
      "c" : {
        "x" : 277,
        "y" : 233
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 277,
        "y" : 233
      }
    },
    "reactionShape" : {
      "c" : {
        "x" : 287,
        "y" : 174
      },
      "r" : 5,
      "type" : "CIRCLE",
      "centre" : {
        "x" : 287,
        "y" : 174
      }
    },
    "inputs" : [ {
      "id" : 75671,
      "points" : [ {
        "x" : 281,
        "y" : 116
      } ]
    }, {
      "id" : 75662,
      "points" : [ {
        "x" : 363,
        "y" : 78
      } ]
    } ],
    "outputs" : [ {
      "id" : 75672
    } ]
  }, {
    "id" : 75801,
    "reactomeId" : 10316979,
    "displayName" : "GDIs block activation of RHOG",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 118,
      "y" : 339
    },
    "minX" : 91,
    "maxX" : 141,
    "minY" : 333,
    "maxY" : 345,
    "reactionType" : "binding",
    "segments" : [ {
      "from" : {
        "x" : 91,
        "y" : 339
      },
      "to" : {
        "x" : 118,
        "y" : 339
      }
    }, {
      "from" : {
        "x" : 118,
        "y" : 339
      },
      "to" : {
        "x" : 141,
        "y" : 338
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 134,
        "y" : 342
      },
      "b" : {
        "x" : 141,
        "y" : 338
      },
      "c" : {
        "x" : 134,
        "y" : 334
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 134,
        "y" : 334
      }
    },
    "reactionShape" : {
      "c" : {
        "x" : 118,
        "y" : 339
      },
      "r" : 5,
      "type" : "CIRCLE",
      "centre" : {
        "x" : 118,
        "y" : 339
      }
    },
    "inputs" : [ {
      "id" : 75802,
      "points" : [ {
        "x" : 100,
        "y" : 309
      } ]
    }, {
      "id" : 75793,
      "points" : [ {
        "x" : 61,
        "y" : 373
      } ]
    } ],
    "outputs" : [ {
      "id" : 75803
    } ]
  }, {
    "id" : 75673,
    "reactomeId" : 10316626,
    "displayName" : "RHOA binds effectors at the plasma membrane",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 719,
      "y" : 68
    },
    "minX" : 698,
    "maxX" : 749,
    "minY" : 62,
    "maxY" : 74,
    "reactionType" : "binding",
    "segments" : [ {
      "from" : {
        "x" : 698,
        "y" : 69
      },
      "to" : {
        "x" : 719,
        "y" : 68
      }
    }, {
      "from" : {
        "x" : 719,
        "y" : 68
      },
      "to" : {
        "x" : 749,
        "y" : 65
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 743,
        "y" : 70
      },
      "b" : {
        "x" : 749,
        "y" : 65
      },
      "c" : {
        "x" : 742,
        "y" : 62
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 742,
        "y" : 62
      }
    },
    "reactionShape" : {
      "c" : {
        "x" : 719,
        "y" : 68
      },
      "r" : 5,
      "type" : "CIRCLE",
      "centre" : {
        "x" : 719,
        "y" : 68
      }
    },
    "inputs" : [ {
      "id" : 75664,
      "points" : [ {
        "x" : 682,
        "y" : 67
      } ]
    }, {
      "id" : 75674,
      "points" : [ {
        "x" : 726,
        "y" : 127
      } ]
    } ],
    "outputs" : [ {
      "id" : 75675
    } ]
  }, {
    "id" : 75804,
    "reactomeId" : 10316967,
    "displayName" : "RHOG binds effectors at the plasma membrane",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 93,
      "y" : 642
    },
    "minX" : 71,
    "maxX" : 105,
    "minY" : 612,
    "maxY" : 694,
    "reactionType" : "binding",
    "segments" : [ {
      "from" : {
        "x" : 105,
        "y" : 612
      },
      "to" : {
        "x" : 93,
        "y" : 642
      }
    }, {
      "from" : {
        "x" : 93,
        "y" : 642
      },
      "to" : {
        "x" : 71,
        "y" : 694
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 70,
        "y" : 686
      },
      "b" : {
        "x" : 71,
        "y" : 694
      },
      "c" : {
        "x" : 77,
        "y" : 689
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 77,
        "y" : 689
      }
    },
    "reactionShape" : {
      "c" : {
        "x" : 93,
        "y" : 642
      },
      "r" : 5,
      "type" : "CIRCLE",
      "centre" : {
        "x" : 93,
        "y" : 642
      }
    },
    "inputs" : [ {
      "id" : 75795,
      "points" : [ {
        "x" : 58,
        "y" : 578
      } ]
    }, {
      "id" : 75805,
      "points" : [ {
        "x" : 151,
        "y" : 625
      } ]
    } ],
    "outputs" : [ {
      "id" : 75806
    } ]
  }, {
    "id" : 75676,
    "reactomeId" : 10316578,
    "displayName" : "RHOA:GTP translocates to the ER membrane",
    "schemaClass" : "BlackBoxEvent",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 655,
      "y" : 217
    },
    "minX" : 643,
    "maxX" : 661,
    "minY" : 79,
    "maxY" : 294,
    "reactionType" : "omitted",
    "segments" : [ {
      "from" : {
        "x" : 643,
        "y" : 79
      },
      "to" : {
        "x" : 655,
        "y" : 217
      }
    }, {
      "from" : {
        "x" : 655,
        "y" : 217
      },
      "to" : {
        "x" : 659,
        "y" : 294
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 655,
        "y" : 287
      },
      "b" : {
        "x" : 659,
        "y" : 294
      },
      "c" : {
        "x" : 663,
        "y" : 287
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 663,
        "y" : 287
      }
    },
    "reactionShape" : {
      "a" : {
        "x" : 649,
        "y" : 211
      },
      "b" : {
        "x" : 661,
        "y" : 223
      },
      "s" : "\\\\",
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 655,
        "y" : 217
      }
    },
    "inputs" : [ {
      "id" : 75664
    } ],
    "outputs" : [ {
      "id" : 75677
    } ]
  }, {
    "id" : 75807,
    "reactomeId" : 10316971,
    "displayName" : "RHOG translocates to the ER membrane",
    "schemaClass" : "BlackBoxEvent",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 348,
      "y" : 639
    },
    "minX" : 84,
    "maxX" : 599,
    "minY" : 512,
    "maxY" : 645,
    "reactionType" : "omitted",
    "segments" : [ {
      "from" : {
        "x" : 84,
        "y" : 572
      },
      "to" : {
        "x" : 348,
        "y" : 639
      }
    }, {
      "from" : {
        "x" : 348,
        "y" : 639
      },
      "to" : {
        "x" : 599,
        "y" : 512
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 595,
        "y" : 519
      },
      "b" : {
        "x" : 599,
        "y" : 512
      },
      "c" : {
        "x" : 591,
        "y" : 512
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 591,
        "y" : 512
      }
    },
    "reactionShape" : {
      "a" : {
        "x" : 342,
        "y" : 633
      },
      "b" : {
        "x" : 354,
        "y" : 645
      },
      "s" : "\\\\",
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 348,
        "y" : 639
      }
    },
    "inputs" : [ {
      "id" : 75795
    } ],
    "outputs" : [ {
      "id" : 75808
    } ]
  }, {
    "id" : 75678,
    "reactomeId" : 10316576,
    "displayName" : "RHOA binds effectors at the ER membrane",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 827,
      "y" : 280
    },
    "minX" : 743,
    "maxX" : 894,
    "minY" : 263,
    "maxY" : 297,
    "reactionType" : "binding",
    "segments" : [ {
      "from" : {
        "x" : 743,
        "y" : 263
      },
      "to" : {
        "x" : 827,
        "y" : 280
      }
    }, {
      "from" : {
        "x" : 827,
        "y" : 280
      },
      "to" : {
        "x" : 894,
        "y" : 297
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 886,
        "y" : 299
      },
      "b" : {
        "x" : 894,
        "y" : 297
      },
      "c" : {
        "x" : 888,
        "y" : 291
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 888,
        "y" : 291
      }
    },
    "reactionShape" : {
      "c" : {
        "x" : 827,
        "y" : 280
      },
      "r" : 5,
      "type" : "CIRCLE",
      "centre" : {
        "x" : 827,
        "y" : 280
      }
    },
    "inputs" : [ {
      "id" : 75677,
      "points" : [ {
        "x" : 680,
        "y" : 294
      } ]
    }, {
      "id" : 75679,
      "points" : [ {
        "x" : 761,
        "y" : 295
      } ]
    } ],
    "outputs" : [ {
      "id" : 75680
    } ]
  }, {
    "id" : 75809,
    "reactomeId" : 10316997,
    "displayName" : "RHOG binds effectors at the ER membrane",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 720,
      "y" : 474
    },
    "minX" : 676,
    "maxX" : 726,
    "minY" : 421,
    "maxY" : 505,
    "reactionType" : "binding",
    "segments" : [ {
      "from" : {
        "x" : 709,
        "y" : 505
      },
      "to" : {
        "x" : 720,
        "y" : 474
      }
    }, {
      "from" : {
        "x" : 720,
        "y" : 474
      },
      "to" : {
        "x" : 676,
        "y" : 421
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 684,
        "y" : 424
      },
      "b" : {
        "x" : 676,
        "y" : 421
      },
      "c" : {
        "x" : 677,
        "y" : 429
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 677,
        "y" : 429
      }
    },
    "reactionShape" : {
      "c" : {
        "x" : 720,
        "y" : 474
      },
      "r" : 5,
      "type" : "CIRCLE",
      "centre" : {
        "x" : 720,
        "y" : 474
      }
    },
    "inputs" : [ {
      "id" : 75808,
      "points" : [ {
        "x" : 660,
        "y" : 500
      } ]
    }, {
      "id" : 75810,
      "points" : [ {
        "x" : 664,
        "y" : 532
      } ]
    } ],
    "outputs" : [ {
      "id" : 75811
    } ]
  }, {
    "id" : 75681,
    "reactomeId" : 10316641,
    "displayName" : "RHOC GEFs activate RHOC",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 51,
      "y" : 1517
    },
    "minX" : 45,
    "maxX" : 57,
    "minY" : 1479,
    "maxY" : 1565,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 54,
        "y" : 1479
      },
      "to" : {
        "x" : 51,
        "y" : 1517
      }
    }, {
      "from" : {
        "x" : 51,
        "y" : 1517
      },
      "to" : {
        "x" : 52,
        "y" : 1565
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 45,
        "y" : 1511
      },
      "b" : {
        "x" : 57,
        "y" : 1523
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 51,
        "y" : 1517
      }
    },
    "inputs" : [ {
      "id" : 75682,
      "points" : [ {
        "x" : 57,
        "y" : 1438
      } ]
    }, {
      "id" : 75683,
      "points" : [ {
        "x" : 98,
        "y" : 1472
      } ]
    } ],
    "outputs" : [ {
      "id" : 75684,
      "points" : [ {
        "x" : 52,
        "y" : 1602
      } ]
    }, {
      "id" : 75685,
      "points" : [ {
        "x" : 120,
        "y" : 1566
      } ]
    } ],
    "catalysts" : [ {
      "id" : 75686,
      "points" : [ {
        "x" : 100,
        "y" : 1515
      } ]
    } ]
  }, {
    "id" : 75812,
    "reactomeId" : 10317197,
    "displayName" : "RHOBTB1 binds GTP",
    "schemaClass" : "BlackBoxEvent",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 490,
      "y" : 1943
    },
    "minX" : 457,
    "maxX" : 541,
    "minY" : 1937,
    "maxY" : 1949,
    "reactionType" : "omitted",
    "segments" : [ {
      "from" : {
        "x" : 457,
        "y" : 1943
      },
      "to" : {
        "x" : 490,
        "y" : 1943
      }
    }, {
      "from" : {
        "x" : 490,
        "y" : 1943
      },
      "to" : {
        "x" : 541,
        "y" : 1944
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 534,
        "y" : 1948
      },
      "b" : {
        "x" : 541,
        "y" : 1944
      },
      "c" : {
        "x" : 534,
        "y" : 1940
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 534,
        "y" : 1940
      }
    },
    "reactionShape" : {
      "a" : {
        "x" : 484,
        "y" : 1937
      },
      "b" : {
        "x" : 496,
        "y" : 1949
      },
      "s" : "\\\\",
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 490,
        "y" : 1943
      }
    },
    "inputs" : [ {
      "id" : 75813,
      "points" : [ {
        "x" : 427,
        "y" : 1941
      } ]
    }, {
      "id" : 75814,
      "points" : [ {
        "x" : 448,
        "y" : 1899
      } ]
    } ],
    "outputs" : [ {
      "id" : 75815
    } ]
  }, {
    "id" : 75687,
    "reactomeId" : 10316656,
    "displayName" : "RHOC GAPs stimulate RHOC GTPase activity",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 231,
      "y" : 1511
    },
    "minX" : 225,
    "maxX" : 237,
    "minY" : 1445,
    "maxY" : 1587,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 231,
        "y" : 1587
      },
      "to" : {
        "x" : 231,
        "y" : 1511
      }
    }, {
      "from" : {
        "x" : 231,
        "y" : 1511
      },
      "to" : {
        "x" : 230,
        "y" : 1445
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 225,
        "y" : 1505
      },
      "b" : {
        "x" : 237,
        "y" : 1517
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 231,
        "y" : 1511
      }
    },
    "inputs" : [ {
      "id" : 75688,
      "points" : [ {
        "x" : 252,
        "y" : 1607
      } ]
    }, {
      "id" : 75684,
      "points" : [ {
        "x" : 92,
        "y" : 1610
      } ]
    } ],
    "outputs" : [ {
      "id" : 75682,
      "points" : [ {
        "x" : 98,
        "y" : 1428
      } ]
    }, {
      "id" : 75689,
      "points" : [ {
        "x" : 252,
        "y" : 1429
      } ]
    } ],
    "catalysts" : [ {
      "id" : 75690,
      "points" : [ {
        "x" : 282,
        "y" : 1511
      } ]
    } ]
  }, {
    "id" : 75816,
    "reactomeId" : 10317221,
    "displayName" : "RHOBTB1 binds interacting proteins at the endosome membrane",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 704,
      "y" : 1943
    },
    "minX" : 664,
    "maxX" : 778,
    "minY" : 1937,
    "maxY" : 1949,
    "reactionType" : "binding",
    "segments" : [ {
      "from" : {
        "x" : 664,
        "y" : 1942
      },
      "to" : {
        "x" : 704,
        "y" : 1943
      }
    }, {
      "from" : {
        "x" : 704,
        "y" : 1943
      },
      "to" : {
        "x" : 778,
        "y" : 1944
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 771,
        "y" : 1948
      },
      "b" : {
        "x" : 778,
        "y" : 1944
      },
      "c" : {
        "x" : 771,
        "y" : 1940
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 771,
        "y" : 1940
      }
    },
    "reactionShape" : {
      "c" : {
        "x" : 704,
        "y" : 1943
      },
      "r" : 5,
      "type" : "CIRCLE",
      "centre" : {
        "x" : 704,
        "y" : 1943
      }
    },
    "inputs" : [ {
      "id" : 75817,
      "points" : [ {
        "x" : 648,
        "y" : 1881
      } ]
    }, {
      "id" : 75815,
      "points" : [ {
        "x" : 640,
        "y" : 1943
      } ]
    } ],
    "outputs" : [ {
      "id" : 75818
    } ]
  }, {
    "id" : 75819,
    "reactomeId" : 10317234,
    "displayName" : "RHOBTB2 binds GTP",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 512,
      "y" : 2194
    },
    "minX" : 457,
    "maxX" : 557,
    "minY" : 2188,
    "maxY" : 2200,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 457,
        "y" : 2195
      },
      "to" : {
        "x" : 512,
        "y" : 2194
      }
    }, {
      "from" : {
        "x" : 512,
        "y" : 2194
      },
      "to" : {
        "x" : 557,
        "y" : 2191
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 550,
        "y" : 2195
      },
      "b" : {
        "x" : 557,
        "y" : 2191
      },
      "c" : {
        "x" : 550,
        "y" : 2187
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 550,
        "y" : 2187
      }
    },
    "reactionShape" : {
      "a" : {
        "x" : 506,
        "y" : 2188
      },
      "b" : {
        "x" : 518,
        "y" : 2200
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 512,
        "y" : 2194
      }
    },
    "inputs" : [ {
      "id" : 75820,
      "points" : [ {
        "x" : 420,
        "y" : 2191
      } ]
    }, {
      "id" : 75821,
      "points" : [ {
        "x" : 450,
        "y" : 2213
      } ]
    } ],
    "outputs" : [ {
      "id" : 75822
    } ],
    "catalysts" : [ {
      "id" : 75823,
      "points" : [ {
        "x" : 513,
        "y" : 2251
      } ]
    } ]
  }, {
    "id" : 75691,
    "reactomeId" : 10316636,
    "displayName" : "GDIs block activation of RHOC",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 264,
      "y" : 1386
    },
    "minX" : 180,
    "maxX" : 324,
    "minY" : 1373,
    "maxY" : 1400,
    "reactionType" : "binding",
    "segments" : [ {
      "from" : {
        "x" : 180,
        "y" : 1400
      },
      "to" : {
        "x" : 264,
        "y" : 1386
      }
    }, {
      "from" : {
        "x" : 264,
        "y" : 1386
      },
      "to" : {
        "x" : 324,
        "y" : 1373
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 318,
        "y" : 1378
      },
      "b" : {
        "x" : 324,
        "y" : 1373
      },
      "c" : {
        "x" : 316,
        "y" : 1371
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 316,
        "y" : 1371
      }
    },
    "reactionShape" : {
      "c" : {
        "x" : 264,
        "y" : 1386
      },
      "r" : 5,
      "type" : "CIRCLE",
      "centre" : {
        "x" : 264,
        "y" : 1386
      }
    },
    "inputs" : [ {
      "id" : 75682,
      "points" : [ {
        "x" : 98,
        "y" : 1416
      } ]
    }, {
      "id" : 75692,
      "points" : [ {
        "x" : 155,
        "y" : 1378
      } ]
    } ],
    "outputs" : [ {
      "id" : 75693
    } ]
  }, {
    "id" : 75694,
    "reactomeId" : 10316651,
    "displayName" : "RHOC binds effectors at the plasma membrane",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 71,
      "y" : 1716
    },
    "minX" : 58,
    "maxX" : 77,
    "minY" : 1656,
    "maxY" : 1788,
    "reactionType" : "binding",
    "segments" : [ {
      "from" : {
        "x" : 72,
        "y" : 1656
      },
      "to" : {
        "x" : 71,
        "y" : 1716
      }
    }, {
      "from" : {
        "x" : 71,
        "y" : 1716
      },
      "to" : {
        "x" : 58,
        "y" : 1788
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 55,
        "y" : 1780
      },
      "b" : {
        "x" : 58,
        "y" : 1788
      },
      "c" : {
        "x" : 63,
        "y" : 1782
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 63,
        "y" : 1782
      }
    },
    "reactionShape" : {
      "c" : {
        "x" : 71,
        "y" : 1716
      },
      "r" : 5,
      "type" : "CIRCLE",
      "centre" : {
        "x" : 71,
        "y" : 1716
      }
    },
    "inputs" : [ {
      "id" : 75684,
      "points" : [ {
        "x" : 57,
        "y" : 1630
      } ]
    }, {
      "id" : 75695,
      "points" : [ {
        "x" : 124,
        "y" : 1667
      } ]
    } ],
    "outputs" : [ {
      "id" : 75696
    } ]
  }, {
    "id" : 75697,
    "reactomeId" : 10316677,
    "displayName" : "RAC1 GEFs activate RAC1",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 1065,
      "y" : 59
    },
    "minX" : 1025,
    "maxX" : 1101,
    "minY" : 53,
    "maxY" : 65,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 1025,
        "y" : 65
      },
      "to" : {
        "x" : 1065,
        "y" : 59
      }
    }, {
      "from" : {
        "x" : 1065,
        "y" : 59
      },
      "to" : {
        "x" : 1101,
        "y" : 60
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 1059,
        "y" : 53
      },
      "b" : {
        "x" : 1071,
        "y" : 65
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 1065,
        "y" : 59
      }
    },
    "inputs" : [ {
      "id" : 75698,
      "points" : [ {
        "x" : 987,
        "y" : 63
      } ]
    }, {
      "id" : 75699,
      "points" : [ {
        "x" : 1009,
        "y" : 88
      } ]
    } ],
    "outputs" : [ {
      "id" : 75700,
      "points" : [ {
        "x" : 1177,
        "y" : 70
      } ]
    }, {
      "id" : 75701,
      "points" : [ {
        "x" : 1127,
        "y" : 93
      } ]
    } ],
    "catalysts" : [ {
      "id" : 75702,
      "points" : [ {
        "x" : 1064,
        "y" : 119
      } ]
    } ]
  }, {
    "id" : 75824,
    "reactomeId" : 10317254,
    "displayName" : "RHOBTB2 binds interacting proteins at the endosome membrane",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 715,
      "y" : 2188
    },
    "minX" : 685,
    "maxX" : 754,
    "minY" : 2182,
    "maxY" : 2194,
    "reactionType" : "binding",
    "segments" : [ {
      "from" : {
        "x" : 685,
        "y" : 2190
      },
      "to" : {
        "x" : 715,
        "y" : 2188
      }
    }, {
      "from" : {
        "x" : 715,
        "y" : 2188
      },
      "to" : {
        "x" : 754,
        "y" : 2190
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 747,
        "y" : 2194
      },
      "b" : {
        "x" : 754,
        "y" : 2190
      },
      "c" : {
        "x" : 747,
        "y" : 2186
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 747,
        "y" : 2186
      }
    },
    "reactionShape" : {
      "c" : {
        "x" : 715,
        "y" : 2188
      },
      "r" : 5,
      "type" : "CIRCLE",
      "centre" : {
        "x" : 715,
        "y" : 2188
      }
    },
    "inputs" : [ {
      "id" : 75825,
      "points" : [ {
        "x" : 684,
        "y" : 2232
      } ]
    }, {
      "id" : 75822,
      "points" : [ {
        "x" : 657,
        "y" : 2189
      } ]
    } ],
    "outputs" : [ {
      "id" : 75826
    } ]
  }, {
    "id" : 75827,
    "reactomeId" : 10317274,
    "displayName" : "RHOV binds GTP",
    "schemaClass" : "BlackBoxEvent",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 648,
      "y" : 2397
    },
    "minX" : 607,
    "maxX" : 678,
    "minY" : 2391,
    "maxY" : 2403,
    "reactionType" : "omitted",
    "segments" : [ {
      "from" : {
        "x" : 607,
        "y" : 2396
      },
      "to" : {
        "x" : 648,
        "y" : 2397
      }
    }, {
      "from" : {
        "x" : 648,
        "y" : 2397
      },
      "to" : {
        "x" : 678,
        "y" : 2397
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 642,
        "y" : 2391
      },
      "b" : {
        "x" : 654,
        "y" : 2403
      },
      "s" : "\\\\",
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 648,
        "y" : 2397
      }
    },
    "inputs" : [ {
      "id" : 75828,
      "points" : [ {
        "x" : 556,
        "y" : 2406
      } ]
    }, {
      "id" : 75829,
      "points" : [ {
        "x" : 573,
        "y" : 2353
      } ]
    } ],
    "outputs" : [ {
      "id" : 75830,
      "points" : [ {
        "x" : 712,
        "y" : 2406
      } ]
    }, {
      "id" : 75831,
      "points" : [ {
        "x" : 706,
        "y" : 2365
      } ]
    } ]
  }, {
    "id" : 75703,
    "reactomeId" : 10316734,
    "displayName" : "RAC1 GAPs stimulate RAC1 GTPase activity",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 1068,
      "y" : 175
    },
    "minX" : 978,
    "maxX" : 1129,
    "minY" : 169,
    "maxY" : 185,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 1129,
        "y" : 185
      },
      "to" : {
        "x" : 1068,
        "y" : 175
      }
    }, {
      "from" : {
        "x" : 1068,
        "y" : 175
      },
      "to" : {
        "x" : 978,
        "y" : 173
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 1062,
        "y" : 169
      },
      "b" : {
        "x" : 1074,
        "y" : 181
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 1068,
        "y" : 175
      }
    },
    "inputs" : [ {
      "id" : 75700,
      "points" : [ {
        "x" : 1205,
        "y" : 89
      } ]
    }, {
      "id" : 75704,
      "points" : [ {
        "x" : 1151,
        "y" : 200
      } ]
    } ],
    "outputs" : [ {
      "id" : 75698,
      "points" : [ {
        "x" : 951,
        "y" : 76
      } ]
    }, {
      "id" : 75705,
      "points" : [ {
        "x" : 936,
        "y" : 198
      } ]
    } ],
    "catalysts" : [ {
      "id" : 75706,
      "points" : [ {
        "x" : 1065,
        "y" : 212
      } ]
    } ]
  }, {
    "id" : 75832,
    "reactomeId" : 10317270,
    "displayName" : "RHOV binds effectors at the plasma membrane",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 826,
      "y" : 2362
    },
    "minX" : 801,
    "maxX" : 857,
    "minY" : 2356,
    "maxY" : 2391,
    "reactionType" : "binding",
    "segments" : [ {
      "from" : {
        "x" : 801,
        "y" : 2364
      },
      "to" : {
        "x" : 826,
        "y" : 2362
      }
    }, {
      "from" : {
        "x" : 826,
        "y" : 2362
      },
      "to" : {
        "x" : 857,
        "y" : 2391
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 849,
        "y" : 2389
      },
      "b" : {
        "x" : 857,
        "y" : 2391
      },
      "c" : {
        "x" : 855,
        "y" : 2383
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 855,
        "y" : 2383
      }
    },
    "reactionShape" : {
      "c" : {
        "x" : 826,
        "y" : 2362
      },
      "r" : 5,
      "type" : "CIRCLE",
      "centre" : {
        "x" : 826,
        "y" : 2362
      }
    },
    "inputs" : [ {
      "id" : 75830,
      "points" : [ {
        "x" : 761,
        "y" : 2401
      } ]
    }, {
      "id" : 75833,
      "points" : [ {
        "x" : 813,
        "y" : 2307
      } ]
    } ],
    "outputs" : [ {
      "id" : 75834
    } ]
  }, {
    "id" : 75707,
    "reactomeId" : 10316804,
    "displayName" : "RAC1 GDIs block activation of RAC1",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 883,
      "y" : 186
    },
    "minX" : 855,
    "maxX" : 913,
    "minY" : 131,
    "maxY" : 220,
    "reactionType" : "binding",
    "segments" : [ {
      "from" : {
        "x" : 913,
        "y" : 131
      },
      "to" : {
        "x" : 883,
        "y" : 186
      }
    }, {
      "from" : {
        "x" : 883,
        "y" : 186
      },
      "to" : {
        "x" : 855,
        "y" : 220
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 856,
        "y" : 212
      },
      "b" : {
        "x" : 855,
        "y" : 220
      },
      "c" : {
        "x" : 862,
        "y" : 217
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 862,
        "y" : 217
      }
    },
    "reactionShape" : {
      "c" : {
        "x" : 883,
        "y" : 186
      },
      "r" : 5,
      "type" : "CIRCLE",
      "centre" : {
        "x" : 883,
        "y" : 186
      }
    },
    "inputs" : [ {
      "id" : 75698,
      "points" : [ {
        "x" : 943,
        "y" : 76
      } ]
    }, {
      "id" : 75671,
      "points" : [ {
        "x" : 231,
        "y" : 101
      }, {
        "x" : 232,
        "y" : 0
      }, {
        "x" : 894,
        "y" : 2
      } ]
    } ],
    "outputs" : [ {
      "id" : 75708
    } ]
  }, {
    "id" : 75835,
    "reactomeId" : 10320331,
    "displayName" : "RAC1 translocates to the endoplasmic reticulum membrane",
    "schemaClass" : "BlackBoxEvent",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 1204,
      "y" : 329
    },
    "minX" : 1006,
    "maxX" : 1213,
    "minY" : 89,
    "maxY" : 407,
    "reactionType" : "omitted",
    "segments" : [ {
      "from" : {
        "x" : 1213,
        "y" : 89
      },
      "to" : {
        "x" : 1204,
        "y" : 329
      }
    }, {
      "from" : {
        "x" : 1204,
        "y" : 329
      },
      "to" : {
        "x" : 1006,
        "y" : 407
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 1011,
        "y" : 401
      },
      "b" : {
        "x" : 1006,
        "y" : 407
      },
      "c" : {
        "x" : 1014,
        "y" : 408
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 1014,
        "y" : 408
      }
    },
    "reactionShape" : {
      "a" : {
        "x" : 1198,
        "y" : 323
      },
      "b" : {
        "x" : 1210,
        "y" : 335
      },
      "s" : "\\\\",
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 1204,
        "y" : 329
      }
    },
    "inputs" : [ {
      "id" : 75700
    } ],
    "outputs" : [ {
      "id" : 75836
    } ]
  }, {
    "id" : 75709,
    "reactomeId" : 10316800,
    "displayName" : "RAC1 binds effectors at the plasma membrane",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 1332,
      "y" : 61
    },
    "minX" : 1306,
    "maxX" : 1369,
    "minY" : 55,
    "maxY" : 102,
    "reactionType" : "binding",
    "segments" : [ {
      "from" : {
        "x" : 1306,
        "y" : 102
      },
      "to" : {
        "x" : 1332,
        "y" : 61
      }
    }, {
      "from" : {
        "x" : 1332,
        "y" : 61
      },
      "to" : {
        "x" : 1369,
        "y" : 62
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 1362,
        "y" : 66
      },
      "b" : {
        "x" : 1369,
        "y" : 62
      },
      "c" : {
        "x" : 1362,
        "y" : 58
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 1362,
        "y" : 58
      }
    },
    "reactionShape" : {
      "c" : {
        "x" : 1332,
        "y" : 61
      },
      "r" : 5,
      "type" : "CIRCLE",
      "centre" : {
        "x" : 1332,
        "y" : 61
      }
    },
    "inputs" : [ {
      "id" : 75700,
      "points" : [ {
        "x" : 1252,
        "y" : 85
      } ]
    }, {
      "id" : 75710,
      "points" : [ {
        "x" : 1284,
        "y" : 144
      } ]
    } ],
    "outputs" : [ {
      "id" : 75711
    } ]
  }, {
    "id" : 75837,
    "reactomeId" : 10320337,
    "displayName" : "RAC1 binds effectors at the ER membrane",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 893,
      "y" : 457
    },
    "minX" : 887,
    "maxX" : 932,
    "minY" : 417,
    "maxY" : 463,
    "reactionType" : "binding",
    "segments" : [ {
      "from" : {
        "x" : 896,
        "y" : 417
      },
      "to" : {
        "x" : 893,
        "y" : 457
      }
    }, {
      "from" : {
        "x" : 893,
        "y" : 457
      },
      "to" : {
        "x" : 932,
        "y" : 463
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 925,
        "y" : 466
      },
      "b" : {
        "x" : 932,
        "y" : 463
      },
      "c" : {
        "x" : 926,
        "y" : 458
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 926,
        "y" : 458
      }
    },
    "reactionShape" : {
      "c" : {
        "x" : 893,
        "y" : 457
      },
      "r" : 5,
      "type" : "CIRCLE",
      "centre" : {
        "x" : 893,
        "y" : 457
      }
    },
    "inputs" : [ {
      "id" : 75836,
      "points" : [ {
        "x" : 943,
        "y" : 419
      } ]
    }, {
      "id" : 75838,
      "points" : [ {
        "x" : 943,
        "y" : 389
      } ]
    } ],
    "outputs" : [ {
      "id" : 75839
    } ]
  }, {
    "id" : 75712,
    "reactomeId" : 10316875,
    "displayName" : "CDC42 GEFs activate CDC42",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 1703,
      "y" : 66
    },
    "minX" : 1663,
    "maxX" : 1753,
    "minY" : 60,
    "maxY" : 72,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 1663,
        "y" : 66
      },
      "to" : {
        "x" : 1703,
        "y" : 66
      }
    }, {
      "from" : {
        "x" : 1703,
        "y" : 66
      },
      "to" : {
        "x" : 1753,
        "y" : 64
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 1697,
        "y" : 60
      },
      "b" : {
        "x" : 1709,
        "y" : 72
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 1703,
        "y" : 66
      }
    },
    "inputs" : [ {
      "id" : 75713,
      "points" : [ {
        "x" : 1611,
        "y" : 63
      } ]
    }, {
      "id" : 75714,
      "points" : [ {
        "x" : 1621,
        "y" : 98
      } ]
    } ],
    "outputs" : [ {
      "id" : 75715,
      "points" : [ {
        "x" : 1798,
        "y" : 63
      } ]
    }, {
      "id" : 75716,
      "points" : [ {
        "x" : 1775,
        "y" : 105
      } ]
    } ],
    "catalysts" : [ {
      "id" : 75717,
      "points" : [ {
        "x" : 1697,
        "y" : 127
      } ]
    } ]
  }, {
    "id" : 75840,
    "reactomeId" : 10320366,
    "displayName" : "CDC42 translocates to the endoplasmic reticulum membrane",
    "schemaClass" : "BlackBoxEvent",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 1856,
      "y" : 316
    },
    "minX" : 1011,
    "maxX" : 1862,
    "minY" : 78,
    "maxY" : 517,
    "reactionType" : "omitted",
    "segments" : [ {
      "from" : {
        "x" : 1843,
        "y" : 78
      },
      "to" : {
        "x" : 1856,
        "y" : 316
      }
    }, {
      "from" : {
        "x" : 1856,
        "y" : 316
      },
      "to" : {
        "x" : 1011,
        "y" : 517
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 1017,
        "y" : 512
      },
      "b" : {
        "x" : 1011,
        "y" : 517
      },
      "c" : {
        "x" : 1019,
        "y" : 519
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 1019,
        "y" : 519
      }
    },
    "reactionShape" : {
      "a" : {
        "x" : 1850,
        "y" : 310
      },
      "b" : {
        "x" : 1862,
        "y" : 322
      },
      "s" : "\\\\",
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 1856,
        "y" : 316
      }
    },
    "inputs" : [ {
      "id" : 75715
    } ],
    "outputs" : [ {
      "id" : 75841
    } ]
  }, {
    "id" : 75842,
    "reactomeId" : 10320372,
    "displayName" : "CDC42 binds effectors at the ER membrane",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 852,
      "y" : 520
    },
    "minX" : 844,
    "maxX" : 928,
    "minY" : 458,
    "maxY" : 584,
    "reactionType" : "binding",
    "segments" : [ {
      "from" : {
        "x" : 844,
        "y" : 458
      },
      "to" : {
        "x" : 852,
        "y" : 520
      }
    }, {
      "from" : {
        "x" : 852,
        "y" : 520
      },
      "to" : {
        "x" : 928,
        "y" : 584
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 920,
        "y" : 583
      },
      "b" : {
        "x" : 928,
        "y" : 584
      },
      "c" : {
        "x" : 925,
        "y" : 576
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 925,
        "y" : 576
      }
    },
    "reactionShape" : {
      "c" : {
        "x" : 852,
        "y" : 520
      },
      "r" : 5,
      "type" : "CIRCLE",
      "centre" : {
        "x" : 852,
        "y" : 520
      }
    },
    "inputs" : [ {
      "id" : 75843,
      "points" : [ {
        "x" : 831,
        "y" : 396
      } ]
    }, {
      "id" : 75841,
      "points" : [ {
        "x" : 947,
        "y" : 513
      } ]
    } ],
    "outputs" : [ {
      "id" : 75844
    } ]
  }, {
    "id" : 75845,
    "reactomeId" : 10320391,
    "displayName" : "RHOF auto-activates",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 3186,
      "y" : 715
    },
    "minX" : 3180,
    "maxX" : 3193,
    "minY" : 684,
    "maxY" : 751,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 3188,
        "y" : 684
      },
      "to" : {
        "x" : 3186,
        "y" : 715
      }
    }, {
      "from" : {
        "x" : 3186,
        "y" : 715
      },
      "to" : {
        "x" : 3193,
        "y" : 751
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 3180,
        "y" : 709
      },
      "b" : {
        "x" : 3192,
        "y" : 721
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 3186,
        "y" : 715
      }
    },
    "inputs" : [ {
      "id" : 75846,
      "points" : [ {
        "x" : 3188,
        "y" : 660
      } ]
    }, {
      "id" : 75847,
      "points" : [ {
        "x" : 3132,
        "y" : 679
      } ]
    } ],
    "outputs" : [ {
      "id" : 75848,
      "points" : [ {
        "x" : 3186,
        "y" : 776
      } ]
    }, {
      "id" : 75849,
      "points" : [ {
        "x" : 3129,
        "y" : 747
      } ]
    } ],
    "catalysts" : [ {
      "id" : 75846,
      "points" : [ {
        "x" : 3199,
        "y" : 660
      }, {
        "x" : 3226,
        "y" : 685
      } ]
    } ]
  }, {
    "id" : 75718,
    "reactomeId" : 10316884,
    "displayName" : "CDC42 GAPs stimulate CDC42 GTPase activity",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 1698,
      "y" : 207
    },
    "minX" : 1577,
    "maxX" : 1812,
    "minY" : 189,
    "maxY" : 213,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 1812,
        "y" : 189
      },
      "to" : {
        "x" : 1698,
        "y" : 207
      }
    }, {
      "from" : {
        "x" : 1698,
        "y" : 207
      },
      "to" : {
        "x" : 1577,
        "y" : 198
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 1692,
        "y" : 201
      },
      "b" : {
        "x" : 1704,
        "y" : 213
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 1698,
        "y" : 207
      }
    },
    "inputs" : [ {
      "id" : 75715,
      "points" : [ {
        "x" : 1840,
        "y" : 78
      } ]
    }, {
      "id" : 75719,
      "points" : [ {
        "x" : 1806,
        "y" : 252
      } ]
    } ],
    "outputs" : [ {
      "id" : 75713,
      "points" : [ {
        "x" : 1569,
        "y" : 78
      } ]
    }, {
      "id" : 75720,
      "points" : [ {
        "x" : 1547,
        "y" : 250
      } ]
    } ],
    "catalysts" : [ {
      "id" : 75721,
      "points" : [ {
        "x" : 1697,
        "y" : 273
      } ]
    } ]
  }, {
    "id" : 75850,
    "reactomeId" : 10320434,
    "displayName" : "RHOF GAPs stimulate RHOF GTPase activity",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 3054,
      "y" : 712
    },
    "minX" : 3048,
    "maxX" : 3060,
    "minY" : 645,
    "maxY" : 763,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 3052,
        "y" : 763
      },
      "to" : {
        "x" : 3054,
        "y" : 712
      }
    }, {
      "from" : {
        "x" : 3054,
        "y" : 712
      },
      "to" : {
        "x" : 3052,
        "y" : 645
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 3048,
        "y" : 706
      },
      "b" : {
        "x" : 3060,
        "y" : 718
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 3054,
        "y" : 712
      }
    },
    "inputs" : [ {
      "id" : 75848,
      "points" : [ {
        "x" : 3145,
        "y" : 782
      } ]
    }, {
      "id" : 75851,
      "points" : [ {
        "x" : 3028,
        "y" : 772
      } ]
    } ],
    "outputs" : [ {
      "id" : 75846,
      "points" : [ {
        "x" : 3148,
        "y" : 645
      } ]
    }, {
      "id" : 75852,
      "points" : [ {
        "x" : 3025,
        "y" : 638
      } ]
    } ],
    "catalysts" : [ {
      "id" : 75853,
      "points" : [ {
        "x" : 3019,
        "y" : 712
      } ]
    } ]
  }, {
    "id" : 75722,
    "reactomeId" : 10316864,
    "displayName" : "CDC42 GDIs block activation of CDC42",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 1459,
      "y" : 198
    },
    "minX" : 1453,
    "maxX" : 1469,
    "minY" : 174,
    "maxY" : 236,
    "reactionType" : "binding",
    "segments" : [ {
      "from" : {
        "x" : 1469,
        "y" : 174
      },
      "to" : {
        "x" : 1459,
        "y" : 198
      }
    }, {
      "from" : {
        "x" : 1459,
        "y" : 198
      },
      "to" : {
        "x" : 1461,
        "y" : 236
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 1457,
        "y" : 229
      },
      "b" : {
        "x" : 1461,
        "y" : 236
      },
      "c" : {
        "x" : 1465,
        "y" : 229
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 1465,
        "y" : 229
      }
    },
    "reactionShape" : {
      "c" : {
        "x" : 1459,
        "y" : 198
      },
      "r" : 5,
      "type" : "CIRCLE",
      "centre" : {
        "x" : 1459,
        "y" : 198
      }
    },
    "inputs" : [ {
      "id" : 75723,
      "points" : [ {
        "x" : 1422,
        "y" : 147
      } ]
    }, {
      "id" : 75713,
      "points" : [ {
        "x" : 1557,
        "y" : 78
      } ]
    } ],
    "outputs" : [ {
      "id" : 75724
    } ]
  }, {
    "id" : 75725,
    "reactomeId" : 10316852,
    "displayName" : "CDC42 binds effectors at the plasma membrane",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 1944,
      "y" : 174
    },
    "minX" : 1938,
    "maxX" : 1950,
    "minY" : 138,
    "maxY" : 264,
    "reactionType" : "binding",
    "segments" : [ {
      "from" : {
        "x" : 1942,
        "y" : 138
      },
      "to" : {
        "x" : 1944,
        "y" : 174
      }
    }, {
      "from" : {
        "x" : 1944,
        "y" : 174
      },
      "to" : {
        "x" : 1946,
        "y" : 264
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 1942,
        "y" : 257
      },
      "b" : {
        "x" : 1946,
        "y" : 264
      },
      "c" : {
        "x" : 1950,
        "y" : 257
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 1950,
        "y" : 257
      }
    },
    "reactionShape" : {
      "c" : {
        "x" : 1944,
        "y" : 174
      },
      "r" : 5,
      "type" : "CIRCLE",
      "centre" : {
        "x" : 1944,
        "y" : 174
      }
    },
    "inputs" : [ {
      "id" : 75715,
      "points" : [ {
        "x" : 1858,
        "y" : 78
      } ]
    }, {
      "id" : 75726,
      "points" : [ {
        "x" : 1976,
        "y" : 154
      } ]
    } ],
    "outputs" : [ {
      "id" : 75727
    } ]
  }, {
    "id" : 75854,
    "reactomeId" : 10320427,
    "displayName" : "RHOF binds effectors at the plasma membrane",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 3124,
      "y" : 825
    },
    "minX" : 3086,
    "maxX" : 3166,
    "minY" : 800,
    "maxY" : 857,
    "reactionType" : "binding",
    "segments" : [ {
      "from" : {
        "x" : 3086,
        "y" : 800
      },
      "to" : {
        "x" : 3124,
        "y" : 825
      }
    }, {
      "from" : {
        "x" : 3124,
        "y" : 825
      },
      "to" : {
        "x" : 3166,
        "y" : 857
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 3158,
        "y" : 856
      },
      "b" : {
        "x" : 3166,
        "y" : 857
      },
      "c" : {
        "x" : 3163,
        "y" : 850
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 3163,
        "y" : 850
      }
    },
    "reactionShape" : {
      "c" : {
        "x" : 3124,
        "y" : 825
      },
      "r" : 5,
      "type" : "CIRCLE",
      "centre" : {
        "x" : 3124,
        "y" : 825
      }
    },
    "inputs" : [ {
      "id" : 75855,
      "points" : [ {
        "x" : 3003,
        "y" : 818
      } ]
    }, {
      "id" : 75848,
      "points" : [ {
        "x" : 3145,
        "y" : 793
      } ]
    } ],
    "outputs" : [ {
      "id" : 75856
    } ]
  }, {
    "id" : 75857,
    "reactomeId" : 10317118,
    "displayName" : "GDIs bind RHOH",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 3057,
      "y" : 1965
    },
    "minX" : 3005,
    "maxX" : 3111,
    "minY" : 1946,
    "maxY" : 1996,
    "reactionType" : "binding",
    "segments" : [ {
      "from" : {
        "x" : 3111,
        "y" : 1996
      },
      "to" : {
        "x" : 3057,
        "y" : 1965
      }
    }, {
      "from" : {
        "x" : 3057,
        "y" : 1965
      },
      "to" : {
        "x" : 3005,
        "y" : 1946
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 3013,
        "y" : 1945
      },
      "b" : {
        "x" : 3005,
        "y" : 1946
      },
      "c" : {
        "x" : 3010,
        "y" : 1952
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 3010,
        "y" : 1952
      }
    },
    "reactionShape" : {
      "c" : {
        "x" : 3057,
        "y" : 1965
      },
      "r" : 5,
      "type" : "CIRCLE",
      "centre" : {
        "x" : 3057,
        "y" : 1965
      }
    },
    "inputs" : [ {
      "id" : 75759,
      "points" : [ {
        "x" : 3165,
        "y" : 2028
      } ]
    }, {
      "id" : 75858,
      "points" : [ {
        "x" : 3048,
        "y" : 2013
      } ]
    } ],
    "outputs" : [ {
      "id" : 75859
    } ]
  }, {
    "id" : 75728,
    "reactomeId" : 10317060,
    "displayName" : "RHOJ GEFs activate RHOJ",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 3161,
      "y" : 1034
    },
    "minX" : 3155,
    "maxX" : 3167,
    "minY" : 1005,
    "maxY" : 1079,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 3161,
        "y" : 1005
      },
      "to" : {
        "x" : 3161,
        "y" : 1034
      }
    }, {
      "from" : {
        "x" : 3161,
        "y" : 1034
      },
      "to" : {
        "x" : 3161,
        "y" : 1079
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 3155,
        "y" : 1028
      },
      "b" : {
        "x" : 3167,
        "y" : 1040
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 3161,
        "y" : 1034
      }
    },
    "inputs" : [ {
      "id" : 75729,
      "points" : [ {
        "x" : 3161,
        "y" : 967
      } ]
    }, {
      "id" : 75730,
      "points" : [ {
        "x" : 3118,
        "y" : 990
      } ]
    } ],
    "outputs" : [ {
      "id" : 75731,
      "points" : [ {
        "x" : 3158,
        "y" : 1121
      } ]
    }, {
      "id" : 75732,
      "points" : [ {
        "x" : 3122,
        "y" : 1084
      } ]
    } ],
    "catalysts" : [ {
      "id" : 75733,
      "points" : [ {
        "x" : 3117,
        "y" : 1035
      } ]
    } ]
  }, {
    "id" : 75860,
    "reactomeId" : 10320571,
    "displayName" : "RND1 binds GTP",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 1818,
      "y" : 2412
    },
    "minX" : 1788,
    "maxX" : 1858,
    "minY" : 2406,
    "maxY" : 2418,
    "reactionType" : "binding",
    "segments" : [ {
      "from" : {
        "x" : 1788,
        "y" : 2410
      },
      "to" : {
        "x" : 1818,
        "y" : 2412
      }
    }, {
      "from" : {
        "x" : 1818,
        "y" : 2412
      },
      "to" : {
        "x" : 1858,
        "y" : 2411
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 1851,
        "y" : 2415
      },
      "b" : {
        "x" : 1858,
        "y" : 2411
      },
      "c" : {
        "x" : 1851,
        "y" : 2407
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 1851,
        "y" : 2407
      }
    },
    "reactionShape" : {
      "c" : {
        "x" : 1818,
        "y" : 2412
      },
      "r" : 5,
      "type" : "CIRCLE",
      "centre" : {
        "x" : 1818,
        "y" : 2412
      }
    },
    "inputs" : [ {
      "id" : 75861,
      "points" : [ {
        "x" : 1766,
        "y" : 2412
      } ]
    }, {
      "id" : 75862,
      "points" : [ {
        "x" : 1777,
        "y" : 2384
      } ]
    } ],
    "outputs" : [ {
      "id" : 75863
    } ]
  }, {
    "id" : 75734,
    "reactomeId" : 10317055,
    "displayName" : "RHOJ GAPs stimulate RHOJ GTPase activity",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 2996,
      "y" : 1032
    },
    "minX" : 2990,
    "maxX" : 3002,
    "minY" : 969,
    "maxY" : 1099,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 2998,
        "y" : 1099
      },
      "to" : {
        "x" : 2996,
        "y" : 1032
      }
    }, {
      "from" : {
        "x" : 2996,
        "y" : 1032
      },
      "to" : {
        "x" : 2998,
        "y" : 969
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 2990,
        "y" : 1026
      },
      "b" : {
        "x" : 3002,
        "y" : 1038
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 2996,
        "y" : 1032
      }
    },
    "inputs" : [ {
      "id" : 75731,
      "points" : [ {
        "x" : 3119,
        "y" : 1127
      } ]
    }, {
      "id" : 75735,
      "points" : [ {
        "x" : 2963,
        "y" : 1115
      } ]
    } ],
    "outputs" : [ {
      "id" : 75729,
      "points" : [ {
        "x" : 3121,
        "y" : 955
      } ]
    }, {
      "id" : 75736,
      "points" : [ {
        "x" : 2967,
        "y" : 959
      } ]
    } ],
    "catalysts" : [ {
      "id" : 75737,
      "points" : [ {
        "x" : 2927,
        "y" : 1031
      } ]
    } ]
  }, {
    "id" : 75864,
    "reactomeId" : 10320569,
    "displayName" : "RND1 binds effectors",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 1989,
      "y" : 2412
    },
    "minX" : 1965,
    "maxX" : 2036,
    "minY" : 2406,
    "maxY" : 2418,
    "reactionType" : "binding",
    "segments" : [ {
      "from" : {
        "x" : 1965,
        "y" : 2414
      },
      "to" : {
        "x" : 1989,
        "y" : 2412
      }
    }, {
      "from" : {
        "x" : 1989,
        "y" : 2412
      },
      "to" : {
        "x" : 2036,
        "y" : 2413
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 2029,
        "y" : 2417
      },
      "b" : {
        "x" : 2036,
        "y" : 2413
      },
      "c" : {
        "x" : 2029,
        "y" : 2409
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 2029,
        "y" : 2409
      }
    },
    "reactionShape" : {
      "c" : {
        "x" : 1989,
        "y" : 2412
      },
      "r" : 5,
      "type" : "CIRCLE",
      "centre" : {
        "x" : 1989,
        "y" : 2412
      }
    },
    "inputs" : [ {
      "id" : 75863,
      "points" : [ {
        "x" : 1937,
        "y" : 2412
      } ]
    }, {
      "id" : 75865,
      "points" : [ {
        "x" : 1936,
        "y" : 2369
      } ]
    } ],
    "outputs" : [ {
      "id" : 75866
    } ]
  }, {
    "id" : 75867,
    "reactomeId" : 10320573,
    "displayName" : "RND2 binds GTP",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 2278,
      "y" : 2414
    },
    "minX" : 2250,
    "maxX" : 2316,
    "minY" : 2408,
    "maxY" : 2420,
    "reactionType" : "binding",
    "segments" : [ {
      "from" : {
        "x" : 2250,
        "y" : 2413
      },
      "to" : {
        "x" : 2278,
        "y" : 2414
      }
    }, {
      "from" : {
        "x" : 2278,
        "y" : 2414
      },
      "to" : {
        "x" : 2316,
        "y" : 2414
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 2309,
        "y" : 2418
      },
      "b" : {
        "x" : 2316,
        "y" : 2414
      },
      "c" : {
        "x" : 2309,
        "y" : 2410
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 2309,
        "y" : 2410
      }
    },
    "reactionShape" : {
      "c" : {
        "x" : 2278,
        "y" : 2414
      },
      "r" : 5,
      "type" : "CIRCLE",
      "centre" : {
        "x" : 2278,
        "y" : 2414
      }
    },
    "inputs" : [ {
      "id" : 75868,
      "points" : [ {
        "x" : 2222,
        "y" : 2413
      } ]
    }, {
      "id" : 75869,
      "points" : [ {
        "x" : 2235,
        "y" : 2376
      } ]
    } ],
    "outputs" : [ {
      "id" : 75870
    } ]
  }, {
    "id" : 75738,
    "reactomeId" : 10317108,
    "displayName" : "RHOQ GEFs activate RHOQ",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 3159,
      "y" : 1467
    },
    "minX" : 3153,
    "maxX" : 3165,
    "minY" : 1421,
    "maxY" : 1513,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 3158,
        "y" : 1421
      },
      "to" : {
        "x" : 3159,
        "y" : 1467
      }
    }, {
      "from" : {
        "x" : 3159,
        "y" : 1467
      },
      "to" : {
        "x" : 3158,
        "y" : 1513
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 3153,
        "y" : 1461
      },
      "b" : {
        "x" : 3165,
        "y" : 1473
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 3159,
        "y" : 1467
      }
    },
    "inputs" : [ {
      "id" : 75739,
      "points" : [ {
        "x" : 3156,
        "y" : 1352
      } ]
    }, {
      "id" : 75740,
      "points" : [ {
        "x" : 3117,
        "y" : 1414
      } ]
    } ],
    "outputs" : [ {
      "id" : 75741,
      "points" : [ {
        "x" : 3158,
        "y" : 1556
      } ]
    }, {
      "id" : 75742,
      "points" : [ {
        "x" : 3107,
        "y" : 1522
      } ]
    } ],
    "catalysts" : [ {
      "id" : 75743,
      "points" : [ {
        "x" : 3084,
        "y" : 1463
      } ]
    } ]
  }, {
    "id" : 75871,
    "reactomeId" : 10320523,
    "displayName" : "RND2 binds effectors",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 2465,
      "y" : 2412
    },
    "minX" : 2432,
    "maxX" : 2502,
    "minY" : 2406,
    "maxY" : 2418,
    "reactionType" : "binding",
    "segments" : [ {
      "from" : {
        "x" : 2432,
        "y" : 2410
      },
      "to" : {
        "x" : 2465,
        "y" : 2412
      }
    }, {
      "from" : {
        "x" : 2465,
        "y" : 2412
      },
      "to" : {
        "x" : 2502,
        "y" : 2412
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 2495,
        "y" : 2416
      },
      "b" : {
        "x" : 2502,
        "y" : 2412
      },
      "c" : {
        "x" : 2495,
        "y" : 2408
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 2495,
        "y" : 2408
      }
    },
    "reactionShape" : {
      "c" : {
        "x" : 2465,
        "y" : 2412
      },
      "r" : 5,
      "type" : "CIRCLE",
      "centre" : {
        "x" : 2465,
        "y" : 2412
      }
    },
    "inputs" : [ {
      "id" : 75870,
      "points" : [ {
        "x" : 2399,
        "y" : 2411
      } ]
    }, {
      "id" : 75872,
      "points" : [ {
        "x" : 2421,
        "y" : 2376
      } ]
    } ],
    "outputs" : [ {
      "id" : 75873
    } ]
  }, {
    "id" : 75744,
    "reactomeId" : 10317093,
    "displayName" : "RHOQ GAPs stimulate RHOQ GTPase activity",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 2974,
      "y" : 1471
    },
    "minX" : 2968,
    "maxX" : 2980,
    "minY" : 1360,
    "maxY" : 1561,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 2980,
        "y" : 1561
      },
      "to" : {
        "x" : 2974,
        "y" : 1471
      }
    }, {
      "from" : {
        "x" : 2974,
        "y" : 1471
      },
      "to" : {
        "x" : 2976,
        "y" : 1360
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 2968,
        "y" : 1465
      },
      "b" : {
        "x" : 2980,
        "y" : 1477
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 2974,
        "y" : 1471
      }
    },
    "inputs" : [ {
      "id" : 75745,
      "points" : [ {
        "x" : 2910,
        "y" : 1558
      } ]
    }, {
      "id" : 75741,
      "points" : [ {
        "x" : 3120,
        "y" : 1568
      } ]
    } ],
    "outputs" : [ {
      "id" : 75739,
      "points" : [ {
        "x" : 3117,
        "y" : 1342
      } ]
    }, {
      "id" : 75746,
      "points" : [ {
        "x" : 2929,
        "y" : 1344
      } ]
    } ],
    "catalysts" : [ {
      "id" : 75747,
      "points" : [ {
        "x" : 2915,
        "y" : 1469
      } ]
    } ]
  }, {
    "id" : 75874,
    "reactomeId" : 10320531,
    "displayName" : "RND3 binds GTP",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 2765,
      "y" : 2413
    },
    "minX" : 2732,
    "maxX" : 2811,
    "minY" : 2407,
    "maxY" : 2419,
    "reactionType" : "binding",
    "segments" : [ {
      "from" : {
        "x" : 2732,
        "y" : 2413
      },
      "to" : {
        "x" : 2765,
        "y" : 2413
      }
    }, {
      "from" : {
        "x" : 2765,
        "y" : 2413
      },
      "to" : {
        "x" : 2811,
        "y" : 2412
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 2804,
        "y" : 2416
      },
      "b" : {
        "x" : 2811,
        "y" : 2412
      },
      "c" : {
        "x" : 2804,
        "y" : 2408
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 2804,
        "y" : 2408
      }
    },
    "reactionShape" : {
      "c" : {
        "x" : 2765,
        "y" : 2413
      },
      "r" : 5,
      "type" : "CIRCLE",
      "centre" : {
        "x" : 2765,
        "y" : 2413
      }
    },
    "inputs" : [ {
      "id" : 75875,
      "points" : [ {
        "x" : 2699,
        "y" : 2413
      } ]
    }, {
      "id" : 75876,
      "points" : [ {
        "x" : 2720,
        "y" : 2378
      } ]
    } ],
    "outputs" : [ {
      "id" : 75877
    } ]
  }, {
    "id" : 75748,
    "reactomeId" : 10317103,
    "displayName" : "RHOQ binds effectors at the plasma membrane",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 3139,
      "y" : 1697
    },
    "minX" : 3133,
    "maxX" : 3165,
    "minY" : 1653,
    "maxY" : 1755,
    "reactionType" : "binding",
    "segments" : [ {
      "from" : {
        "x" : 3137,
        "y" : 1653
      },
      "to" : {
        "x" : 3139,
        "y" : 1697
      }
    }, {
      "from" : {
        "x" : 3139,
        "y" : 1697
      },
      "to" : {
        "x" : 3165,
        "y" : 1755
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 3159,
        "y" : 1750
      },
      "b" : {
        "x" : 3165,
        "y" : 1755
      },
      "c" : {
        "x" : 3166,
        "y" : 1747
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 3166,
        "y" : 1747
      }
    },
    "reactionShape" : {
      "c" : {
        "x" : 3139,
        "y" : 1697
      },
      "r" : 5,
      "type" : "CIRCLE",
      "centre" : {
        "x" : 3139,
        "y" : 1697
      }
    },
    "inputs" : [ {
      "id" : 75741,
      "points" : [ {
        "x" : 3156,
        "y" : 1584
      } ]
    }, {
      "id" : 75749,
      "points" : [ {
        "x" : 3072,
        "y" : 1615
      } ]
    } ],
    "outputs" : [ {
      "id" : 75750
    } ]
  }, {
    "id" : 75751,
    "reactomeId" : 10317301,
    "displayName" : "RHOQ translocates to the Golgi-associated vesicle membranes",
    "schemaClass" : "BlackBoxEvent",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 2790,
      "y" : 1583
    },
    "minX" : 2701,
    "maxX" : 3120,
    "minY" : 1505,
    "maxY" : 1589,
    "reactionType" : "omitted",
    "segments" : [ {
      "from" : {
        "x" : 3120,
        "y" : 1571
      },
      "to" : {
        "x" : 2790,
        "y" : 1583
      }
    }, {
      "from" : {
        "x" : 2790,
        "y" : 1583
      },
      "to" : {
        "x" : 2701,
        "y" : 1505
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 2709,
        "y" : 1507
      },
      "b" : {
        "x" : 2701,
        "y" : 1505
      },
      "c" : {
        "x" : 2704,
        "y" : 1513
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 2704,
        "y" : 1513
      }
    },
    "reactionShape" : {
      "a" : {
        "x" : 2784,
        "y" : 1577
      },
      "b" : {
        "x" : 2796,
        "y" : 1589
      },
      "s" : "\\\\",
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 2790,
        "y" : 1583
      }
    },
    "inputs" : [ {
      "id" : 75741
    } ],
    "outputs" : [ {
      "id" : 75752
    } ]
  }, {
    "id" : 75878,
    "reactomeId" : 10320547,
    "displayName" : "RND3 binds effectors",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 2986,
      "y" : 2411
    },
    "minX" : 2935,
    "maxX" : 3029,
    "minY" : 2405,
    "maxY" : 2417,
    "reactionType" : "binding",
    "segments" : [ {
      "from" : {
        "x" : 2935,
        "y" : 2414
      },
      "to" : {
        "x" : 2986,
        "y" : 2411
      }
    }, {
      "from" : {
        "x" : 2986,
        "y" : 2411
      },
      "to" : {
        "x" : 3029,
        "y" : 2411
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 3022,
        "y" : 2415
      },
      "b" : {
        "x" : 3029,
        "y" : 2411
      },
      "c" : {
        "x" : 3022,
        "y" : 2407
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 3022,
        "y" : 2407
      }
    },
    "reactionShape" : {
      "c" : {
        "x" : 2986,
        "y" : 2411
      },
      "r" : 5,
      "type" : "CIRCLE",
      "centre" : {
        "x" : 2986,
        "y" : 2411
      }
    },
    "inputs" : [ {
      "id" : 75877,
      "points" : [ {
        "x" : 2894,
        "y" : 2412
      } ]
    }, {
      "id" : 75879,
      "points" : [ {
        "x" : 2918,
        "y" : 2362
      } ]
    } ],
    "outputs" : [ {
      "id" : 75880
    } ]
  }, {
    "id" : 75753,
    "reactomeId" : 10290586,
    "displayName" : "RHOQ binds GOPC:CFTR",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 2637,
      "y" : 1431
    },
    "minX" : 2597,
    "maxX" : 2667,
    "minY" : 1405,
    "maxY" : 1449,
    "reactionType" : "binding",
    "segments" : [ {
      "from" : {
        "x" : 2597,
        "y" : 1449
      },
      "to" : {
        "x" : 2637,
        "y" : 1431
      }
    }, {
      "from" : {
        "x" : 2637,
        "y" : 1431
      },
      "to" : {
        "x" : 2667,
        "y" : 1405
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 2664,
        "y" : 1413
      },
      "b" : {
        "x" : 2667,
        "y" : 1405
      },
      "c" : {
        "x" : 2659,
        "y" : 1407
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 2659,
        "y" : 1407
      }
    },
    "reactionShape" : {
      "c" : {
        "x" : 2637,
        "y" : 1431
      },
      "r" : 5,
      "type" : "CIRCLE",
      "centre" : {
        "x" : 2637,
        "y" : 1431
      }
    },
    "inputs" : [ {
      "id" : 75754,
      "points" : [ {
        "x" : 2574,
        "y" : 1412
      } ]
    }, {
      "id" : 75752,
      "points" : [ {
        "x" : 2664,
        "y" : 1477
      } ]
    } ],
    "outputs" : [ {
      "id" : 75755
    } ]
  }, {
    "id" : 75881,
    "reactomeId" : 10321631,
    "displayName" : "RAC2 translocates to the ER membrane",
    "schemaClass" : "BlackBoxEvent",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 2828,
      "y" : 269
    },
    "minX" : 925,
    "maxX" : 2834,
    "minY" : 81,
    "maxY" : 1063,
    "reactionType" : "omitted",
    "segments" : [ {
      "from" : {
        "x" : 2775,
        "y" : 81
      },
      "to" : {
        "x" : 2828,
        "y" : 269
      }
    }, {
      "from" : {
        "x" : 2828,
        "y" : 269
      },
      "to" : {
        "x" : 2637,
        "y" : 505
      }
    }, {
      "from" : {
        "x" : 2637,
        "y" : 505
      },
      "to" : {
        "x" : 2765,
        "y" : 1053
      }
    }, {
      "from" : {
        "x" : 2765,
        "y" : 1053
      },
      "to" : {
        "x" : 1084,
        "y" : 1063
      }
    }, {
      "from" : {
        "x" : 1084,
        "y" : 1063
      },
      "to" : {
        "x" : 925,
        "y" : 818
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 932,
        "y" : 822
      },
      "b" : {
        "x" : 925,
        "y" : 818
      },
      "c" : {
        "x" : 925,
        "y" : 826
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 925,
        "y" : 826
      }
    },
    "reactionShape" : {
      "a" : {
        "x" : 2822,
        "y" : 263
      },
      "b" : {
        "x" : 2834,
        "y" : 275
      },
      "s" : "\\\\",
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 2828,
        "y" : 269
      }
    },
    "inputs" : [ {
      "id" : 75774
    } ],
    "outputs" : [ {
      "id" : 75882
    } ]
  }, {
    "id" : 75883,
    "reactomeId" : 10321629,
    "displayName" : "RAC2 binds effectors at the ER membrane",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 784,
      "y" : 690
    },
    "minX" : 738,
    "maxX" : 808,
    "minY" : 668,
    "maxY" : 710,
    "reactionType" : "binding",
    "segments" : [ {
      "from" : {
        "x" : 808,
        "y" : 668
      },
      "to" : {
        "x" : 784,
        "y" : 690
      }
    }, {
      "from" : {
        "x" : 784,
        "y" : 690
      },
      "to" : {
        "x" : 738,
        "y" : 710
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 743,
        "y" : 704
      },
      "b" : {
        "x" : 738,
        "y" : 710
      },
      "c" : {
        "x" : 746,
        "y" : 711
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 746,
        "y" : 711
      }
    },
    "reactionShape" : {
      "c" : {
        "x" : 784,
        "y" : 690
      },
      "r" : 5,
      "type" : "CIRCLE",
      "centre" : {
        "x" : 784,
        "y" : 690
      }
    },
    "inputs" : [ {
      "id" : 75884,
      "points" : [ {
        "x" : 708,
        "y" : 644
      } ]
    }, {
      "id" : 75882,
      "points" : [ {
        "x" : 909,
        "y" : 790
      } ]
    } ],
    "outputs" : [ {
      "id" : 75885
    } ]
  }, {
    "id" : 75756,
    "reactomeId" : 10317120,
    "displayName" : "RHOH binds GTP",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 3181,
      "y" : 1972
    },
    "minX" : 3175,
    "maxX" : 3187,
    "minY" : 1932,
    "maxY" : 2028,
    "reactionType" : "binding",
    "segments" : [ {
      "from" : {
        "x" : 3178,
        "y" : 1932
      },
      "to" : {
        "x" : 3181,
        "y" : 1972
      }
    }, {
      "from" : {
        "x" : 3181,
        "y" : 1972
      },
      "to" : {
        "x" : 3182,
        "y" : 2028
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 3178,
        "y" : 2021
      },
      "b" : {
        "x" : 3182,
        "y" : 2028
      },
      "c" : {
        "x" : 3186,
        "y" : 2021
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 3186,
        "y" : 2021
      }
    },
    "reactionShape" : {
      "c" : {
        "x" : 3181,
        "y" : 1972
      },
      "r" : 5,
      "type" : "CIRCLE",
      "centre" : {
        "x" : 3181,
        "y" : 1972
      }
    },
    "inputs" : [ {
      "id" : 75757,
      "points" : [ {
        "x" : 3176,
        "y" : 1900
      } ]
    }, {
      "id" : 75758,
      "points" : [ {
        "x" : 3138,
        "y" : 1936
      } ]
    } ],
    "outputs" : [ {
      "id" : 75759
    } ]
  }, {
    "id" : 75886,
    "reactomeId" : 10321615,
    "displayName" : "RAC2 translocates to the mitochondrial membrane",
    "schemaClass" : "BlackBoxEvent",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 2805,
      "y" : 272
    },
    "minX" : 2147,
    "maxX" : 2811,
    "minY" : 81,
    "maxY" : 655,
    "reactionType" : "omitted",
    "segments" : [ {
      "from" : {
        "x" : 2774,
        "y" : 81
      },
      "to" : {
        "x" : 2805,
        "y" : 272
      }
    }, {
      "from" : {
        "x" : 2805,
        "y" : 272
      },
      "to" : {
        "x" : 2587,
        "y" : 463
      }
    }, {
      "from" : {
        "x" : 2587,
        "y" : 463
      },
      "to" : {
        "x" : 2561,
        "y" : 655
      }
    }, {
      "from" : {
        "x" : 2561,
        "y" : 655
      },
      "to" : {
        "x" : 2147,
        "y" : 565
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 2155,
        "y" : 563
      },
      "b" : {
        "x" : 2147,
        "y" : 565
      },
      "c" : {
        "x" : 2153,
        "y" : 570
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 2153,
        "y" : 570
      }
    },
    "reactionShape" : {
      "a" : {
        "x" : 2799,
        "y" : 266
      },
      "b" : {
        "x" : 2811,
        "y" : 278
      },
      "s" : "\\\\",
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 2805,
        "y" : 272
      }
    },
    "inputs" : [ {
      "id" : 75774
    } ],
    "outputs" : [ {
      "id" : 75887
    } ]
  }, {
    "id" : 75888,
    "reactomeId" : 10321613,
    "displayName" : "RAC2 binds effectors at the mitochondrial outer membrane",
    "schemaClass" : "BlackBoxEvent",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 1989,
      "y" : 618
    },
    "minX" : 1932,
    "maxX" : 2014,
    "minY" : 590,
    "maxY" : 630,
    "reactionType" : "omitted",
    "segments" : [ {
      "from" : {
        "x" : 2014,
        "y" : 590
      },
      "to" : {
        "x" : 1989,
        "y" : 618
      }
    }, {
      "from" : {
        "x" : 1989,
        "y" : 618
      },
      "to" : {
        "x" : 1932,
        "y" : 630
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 1938,
        "y" : 625
      },
      "b" : {
        "x" : 1932,
        "y" : 630
      },
      "c" : {
        "x" : 1940,
        "y" : 632
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 1940,
        "y" : 632
      }
    },
    "reactionShape" : {
      "a" : {
        "x" : 1983,
        "y" : 612
      },
      "b" : {
        "x" : 1995,
        "y" : 624
      },
      "s" : "\\\\",
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 1989,
        "y" : 618
      }
    },
    "inputs" : [ {
      "id" : 75887,
      "points" : [ {
        "x" : 2076,
        "y" : 572
      } ]
    }, {
      "id" : 75889,
      "points" : [ {
        "x" : 1797,
        "y" : 593
      } ]
    } ],
    "outputs" : [ {
      "id" : 75890
    } ]
  }, {
    "id" : 75760,
    "reactomeId" : 10317156,
    "displayName" : "RHOH binds effectors at the plasma membrane",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 3184,
      "y" : 2147
    },
    "minX" : 3178,
    "maxX" : 3190,
    "minY" : 2105,
    "maxY" : 2193,
    "reactionType" : "binding",
    "segments" : [ {
      "from" : {
        "x" : 3185,
        "y" : 2105
      },
      "to" : {
        "x" : 3184,
        "y" : 2147
      }
    }, {
      "from" : {
        "x" : 3184,
        "y" : 2147
      },
      "to" : {
        "x" : 3184,
        "y" : 2193
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 3180,
        "y" : 2186
      },
      "b" : {
        "x" : 3184,
        "y" : 2193
      },
      "c" : {
        "x" : 3188,
        "y" : 2186
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 3188,
        "y" : 2186
      }
    },
    "reactionShape" : {
      "c" : {
        "x" : 3184,
        "y" : 2147
      },
      "r" : 5,
      "type" : "CIRCLE",
      "centre" : {
        "x" : 3184,
        "y" : 2147
      }
    },
    "inputs" : [ {
      "id" : 75761,
      "points" : [ {
        "x" : 3147,
        "y" : 2101
      } ]
    }, {
      "id" : 75759,
      "points" : [ {
        "x" : 3183,
        "y" : 2056
      } ]
    } ],
    "outputs" : [ {
      "id" : 75762
    } ]
  }, {
    "id" : 75763,
    "reactomeId" : 10317189,
    "displayName" : "RHOU auto-activates",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 1244,
      "y" : 2409
    },
    "minX" : 1197,
    "maxX" : 1290,
    "minY" : 2403,
    "maxY" : 2415,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 1290,
        "y" : 2410
      },
      "to" : {
        "x" : 1244,
        "y" : 2409
      }
    }, {
      "from" : {
        "x" : 1244,
        "y" : 2409
      },
      "to" : {
        "x" : 1197,
        "y" : 2410
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 1238,
        "y" : 2403
      },
      "b" : {
        "x" : 1250,
        "y" : 2415
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 1244,
        "y" : 2409
      }
    },
    "inputs" : [ {
      "id" : 75764,
      "points" : [ {
        "x" : 1372,
        "y" : 2411
      } ]
    }, {
      "id" : 75765,
      "points" : [ {
        "x" : 1304,
        "y" : 2389
      } ]
    } ],
    "outputs" : [ {
      "id" : 75766,
      "points" : [ {
        "x" : 1151,
        "y" : 2410
      } ]
    }, {
      "id" : 75767,
      "points" : [ {
        "x" : 1171,
        "y" : 2374
      } ]
    } ],
    "catalysts" : [ {
      "id" : 75764,
      "points" : [ {
        "x" : 1372,
        "y" : 2419
      }, {
        "x" : 1258,
        "y" : 2445
      } ]
    } ]
  }, {
    "id" : 75891,
    "reactomeId" : 10321583,
    "displayName" : "RHOC translocates to the endoplasmic reticulum membrane",
    "schemaClass" : "BlackBoxEvent",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 358,
      "y" : 1673
    },
    "minX" : 92,
    "maxX" : 637,
    "minY" : 890,
    "maxY" : 1679,
    "reactionType" : "omitted",
    "segments" : [ {
      "from" : {
        "x" : 92,
        "y" : 1622
      },
      "to" : {
        "x" : 358,
        "y" : 1673
      }
    }, {
      "from" : {
        "x" : 358,
        "y" : 1673
      },
      "to" : {
        "x" : 591,
        "y" : 1395
      }
    }, {
      "from" : {
        "x" : 591,
        "y" : 1395
      },
      "to" : {
        "x" : 637,
        "y" : 890
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 640,
        "y" : 897
      },
      "b" : {
        "x" : 637,
        "y" : 890
      },
      "c" : {
        "x" : 632,
        "y" : 897
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 632,
        "y" : 897
      }
    },
    "reactionShape" : {
      "a" : {
        "x" : 352,
        "y" : 1667
      },
      "b" : {
        "x" : 364,
        "y" : 1679
      },
      "s" : "\\\\",
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 358,
        "y" : 1673
      }
    },
    "inputs" : [ {
      "id" : 75684
    } ],
    "outputs" : [ {
      "id" : 75892
    } ]
  }, {
    "id" : 75893,
    "reactomeId" : 10321581,
    "displayName" : "RHOC activates endoplasmic reticulum effectors",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 775,
      "y" : 862
    },
    "minX" : 747,
    "maxX" : 814,
    "minY" : 856,
    "maxY" : 873,
    "reactionType" : "binding",
    "segments" : [ {
      "from" : {
        "x" : 747,
        "y" : 859
      },
      "to" : {
        "x" : 775,
        "y" : 862
      }
    }, {
      "from" : {
        "x" : 775,
        "y" : 862
      },
      "to" : {
        "x" : 814,
        "y" : 873
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 806,
        "y" : 875
      },
      "b" : {
        "x" : 814,
        "y" : 873
      },
      "c" : {
        "x" : 808,
        "y" : 867
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 808,
        "y" : 867
      }
    },
    "reactionShape" : {
      "c" : {
        "x" : 775,
        "y" : 862
      },
      "r" : 5,
      "type" : "CIRCLE",
      "centre" : {
        "x" : 775,
        "y" : 862
      }
    },
    "inputs" : [ {
      "id" : 75892,
      "points" : [ {
        "x" : 680,
        "y" : 869
      } ]
    }, {
      "id" : 75894,
      "points" : [ {
        "x" : 709,
        "y" : 837
      } ]
    } ],
    "outputs" : [ {
      "id" : 75895
    } ]
  }, {
    "id" : 75768,
    "reactomeId" : 10317184,
    "displayName" : "RHOU binds effectors at the plasma membrane",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 1030,
      "y" : 2371
    },
    "minX" : 1009,
    "maxX" : 1063,
    "minY" : 2347,
    "maxY" : 2398,
    "reactionType" : "binding",
    "segments" : [ {
      "from" : {
        "x" : 1063,
        "y" : 2347
      },
      "to" : {
        "x" : 1030,
        "y" : 2371
      }
    }, {
      "from" : {
        "x" : 1030,
        "y" : 2371
      },
      "to" : {
        "x" : 1009,
        "y" : 2398
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 1010,
        "y" : 2390
      },
      "b" : {
        "x" : 1009,
        "y" : 2398
      },
      "c" : {
        "x" : 1016,
        "y" : 2395
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 1016,
        "y" : 2395
      }
    },
    "reactionShape" : {
      "c" : {
        "x" : 1030,
        "y" : 2371
      },
      "r" : 5,
      "type" : "CIRCLE",
      "centre" : {
        "x" : 1030,
        "y" : 2371
      }
    },
    "inputs" : [ {
      "id" : 75769,
      "points" : [ {
        "x" : 1050,
        "y" : 2318
      } ]
    }, {
      "id" : 75766,
      "points" : [ {
        "x" : 1103,
        "y" : 2397
      } ]
    } ],
    "outputs" : [ {
      "id" : 75770
    } ]
  }, {
    "id" : 75896,
    "reactomeId" : 10321773,
    "displayName" : "Phosphorylated RHOU translocates to the endosome membrane",
    "schemaClass" : "BlackBoxEvent",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 1673,
      "y" : 2151
    },
    "minX" : 959,
    "maxX" : 1679,
    "minY" : 2075,
    "maxY" : 2394,
    "reactionType" : "omitted",
    "segments" : [ {
      "from" : {
        "x" : 1657,
        "y" : 2394
      },
      "to" : {
        "x" : 1673,
        "y" : 2151
      }
    }, {
      "from" : {
        "x" : 1673,
        "y" : 2151
      },
      "to" : {
        "x" : 959,
        "y" : 2075
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 966,
        "y" : 2072
      },
      "b" : {
        "x" : 959,
        "y" : 2075
      },
      "c" : {
        "x" : 965,
        "y" : 2080
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 965,
        "y" : 2080
      }
    },
    "reactionShape" : {
      "a" : {
        "x" : 1667,
        "y" : 2145
      },
      "b" : {
        "x" : 1679,
        "y" : 2157
      },
      "s" : "\\\\",
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 1673,
        "y" : 2151
      }
    },
    "inputs" : [ {
      "id" : 75897
    } ],
    "outputs" : [ {
      "id" : 75898
    } ]
  }, {
    "id" : 75771,
    "reactomeId" : 10316937,
    "displayName" : "RAC2 GEFs activate RAC2",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 2677,
      "y" : 71
    },
    "minX" : 2645,
    "maxX" : 2708,
    "minY" : 65,
    "maxY" : 77,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 2645,
        "y" : 68
      },
      "to" : {
        "x" : 2677,
        "y" : 71
      }
    }, {
      "from" : {
        "x" : 2677,
        "y" : 71
      },
      "to" : {
        "x" : 2708,
        "y" : 69
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 2671,
        "y" : 65
      },
      "b" : {
        "x" : 2683,
        "y" : 77
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 2677,
        "y" : 71
      }
    },
    "inputs" : [ {
      "id" : 75772,
      "points" : [ {
        "x" : 2608,
        "y" : 63
      } ]
    }, {
      "id" : 75773,
      "points" : [ {
        "x" : 2623,
        "y" : 101
      } ]
    } ],
    "outputs" : [ {
      "id" : 75774,
      "points" : [ {
        "x" : 2736,
        "y" : 68
      } ]
    }, {
      "id" : 75775,
      "points" : [ {
        "x" : 2727,
        "y" : 100
      } ]
    } ],
    "catalysts" : [ {
      "id" : 75776,
      "points" : [ {
        "x" : 2677,
        "y" : 156
      } ]
    } ]
  } ],
  "compartments" : [ {
    "id" : 75920,
    "reactomeId" : 171907,
    "displayName" : "endosome lumen",
    "schemaClass" : "Compartment",
    "renderableClass" : "Compartment",
    "position" : {
      "x" : 605,
      "y" : 2067
    },
    "minX" : 322,
    "maxX" : 888,
    "minY" : 1938,
    "maxY" : 2197,
    "prop" : {
      "x" : 322,
      "y" : 1938,
      "width" : 566,
      "height" : 259
    },
    "textPosition" : {
      "x" : 336,
      "y" : 2116
    },
    "insets" : {
      "x" : 332,
      "y" : 1948,
      "width" : 546,
      "height" : 239
    },
    "bgColor" : {
      "r" : 250,
      "g" : 240,
      "b" : 240
    },
    "componentIds" : [ 75815, 75818, 75813, 75812, 75816, 75822, 75826, 75820, 75819, 75824, 75898 ]
  }, {
    "id" : 75910,
    "reactomeId" : 171907,
    "displayName" : "endosome lumen",
    "schemaClass" : "Compartment",
    "renderableClass" : "Compartment",
    "position" : {
      "x" : 2406,
      "y" : 583
    },
    "minX" : 2285,
    "maxX" : 2528,
    "minY" : 480,
    "maxY" : 687,
    "prop" : {
      "x" : 2285,
      "y" : 480,
      "width" : 243,
      "height" : 207
    },
    "textPosition" : {
      "x" : 2347,
      "y" : 567
    },
    "insets" : {
      "x" : 2295,
      "y" : 490,
      "width" : 223,
      "height" : 187
    },
    "bgColor" : {
      "r" : 250,
      "g" : 240,
      "b" : 240
    }
  }, {
    "id" : 75913,
    "reactomeId" : 1222693,
    "displayName" : "phagocytic vesicle membrane",
    "schemaClass" : "Compartment",
    "renderableClass" : "Compartment",
    "position" : {
      "x" : 2801,
      "y" : 468
    },
    "minX" : 2717,
    "maxX" : 2885,
    "minY" : 412,
    "maxY" : 525,
    "prop" : {
      "x" : 2717,
      "y" : 412,
      "width" : 168,
      "height" : 113
    },
    "textPosition" : {
      "x" : 2720,
      "y" : 475
    },
    "bgColor" : {
      "r" : 250,
      "g" : 240,
      "b" : 240
    },
    "componentIds" : [ 75788, 75791, 75790, 75789 ]
  }, {
    "id" : 75912,
    "reactomeId" : 13949,
    "displayName" : "Golgi-associated vesicle membrane",
    "schemaClass" : "Compartment",
    "renderableClass" : "Compartment",
    "position" : {
      "x" : 2588,
      "y" : 1440
    },
    "minX" : 2483,
    "maxX" : 2694,
    "minY" : 1357,
    "maxY" : 1523,
    "prop" : {
      "x" : 2483,
      "y" : 1357,
      "width" : 211,
      "height" : 166
    },
    "textPosition" : {
      "x" : 2486,
      "y" : 1465
    },
    "bgColor" : {
      "r" : 250,
      "g" : 240,
      "b" : 240
    },
    "componentIds" : [ 75752, 75753, 75754, 75755 ]
  }, {
    "id" : 75899,
    "reactomeId" : 70101,
    "displayName" : "cytosol",
    "schemaClass" : "Compartment",
    "renderableClass" : "Compartment",
    "position" : {
      "x" : 1612,
      "y" : 1235
    },
    "minX" : 26,
    "maxX" : 3198,
    "minY" : 46,
    "maxY" : 2424,
    "prop" : {
      "x" : 26,
      "y" : 46,
      "width" : 3172,
      "height" : 2378
    },
    "textPosition" : {
      "x" : 57,
      "y" : 2365
    },
    "insets" : {
      "x" : 36,
      "y" : 56,
      "width" : 3152,
      "height" : 2358
    },
    "bgColor" : {
      "r" : 250,
      "g" : 240,
      "b" : 240
    },
    "componentIds" : [ 75664, 75663, 75660, 75661, 75662, 75666, 75668, 75670, 75671, 75672, 75673, 75675, 75676, 75900, 75669, 75667, 75682, 75684, 75683, 75685, 75687, 75688, 75689, 75691, 75693, 75696, 75698, 75699, 75701, 75697, 75703, 75706, 75705, 75707, 75708, 75709, 75711, 75710, 75712, 75713, 75715, 75714, 75716, 75720, 75718, 75722, 75723, 75724, 75725, 75910, 75719, 75721, 75727, 75728, 75729, 75731, 75730, 75732, 75734, 75735, 75736, 75739, 75741, 75740, 75742, 75738, 75744, 75745, 75746, 75748, 75750, 75751, 75912, 75756, 75759, 75758, 75859, 75760, 75761, 75762, 75763, 75764, 75766, 75765, 75767, 75768, 75769, 75770, 75771, 75772, 75774, 75773, 75775, 75777, 75778, 75779, 75781, 75783, 75784, 75786, 75787, 75913, 75792, 75793, 75795, 75797, 75794, 75796, 75798, 75799, 75800, 75801, 75802, 75803, 75804, 75805, 75806, 75807, 75694, 75827, 75830, 75829, 75831, 75828, 75832, 75833, 75834, 75681, 75704, 75700, 75702, 75717, 75776, 75665, 75678, 75835, 75780, 75918, 75840, 75919, 75845, 75846, 75848, 75847, 75849, 75851, 75853, 75852, 75850, 75854, 75855, 75856, 75743, 75747, 75749, 75737, 75757, 75857, 75674, 75695, 75822, 75824, 75860, 75861, 75863, 75862, 75864, 75866, 75867, 75869, 75868, 75870, 75873, 75871, 75875, 75877, 75874, 75876, 75878, 75880, 75865, 75872, 75879, 75825, 75826, 75920, 75814, 75817, 75821, 75823, 75825, 75690, 75785, 75881, 75886, 75733, 75726, 75891, 75858, 75782, 75692, 75686, 75897, 75896 ]
  }, {
    "id" : 75900,
    "reactomeId" : 17957,
    "displayName" : "endoplasmic reticulum lumen",
    "schemaClass" : "Compartment",
    "renderableClass" : "Compartment",
    "position" : {
      "x" : 865,
      "y" : 596
    },
    "minX" : 605,
    "maxX" : 1125,
    "minY" : 297,
    "maxY" : 895,
    "prop" : {
      "x" : 605,
      "y" : 297,
      "width" : 520,
      "height" : 598
    },
    "textPosition" : {
      "x" : 702,
      "y" : 604
    },
    "insets" : {
      "x" : 615,
      "y" : 307,
      "width" : 500,
      "height" : 578
    },
    "bgColor" : {
      "r" : 250,
      "g" : 240,
      "b" : 240
    },
    "componentIds" : [ 75677, 75901, 75808, 75809, 75836, 75837, 75841, 75842, 75679, 75680, 75838, 75839, 75882, 75884, 75885, 75883, 75810, 75811, 75843, 75844, 75926, 75892, 75894, 75895, 75893 ]
  }, {
    "id" : 75919,
    "reactomeId" : 20699,
    "displayName" : "Golgi membrane",
    "schemaClass" : "Compartment",
    "renderableClass" : "Compartment",
    "position" : {
      "x" : 2633,
      "y" : 850
    },
    "minX" : 2500,
    "maxX" : 2767,
    "minY" : 767,
    "maxY" : 934,
    "prop" : {
      "x" : 2500,
      "y" : 767,
      "width" : 267,
      "height" : 167
    },
    "textPosition" : {
      "x" : 2575,
      "y" : 834
    },
    "bgColor" : {
      "r" : 250,
      "g" : 240,
      "b" : 240
    }
  }, {
    "id" : 75918,
    "reactomeId" : 17906,
    "displayName" : "mitochondrial outer membrane",
    "schemaClass" : "Compartment",
    "renderableClass" : "Compartment",
    "position" : {
      "x" : 1870,
      "y" : 567
    },
    "minX" : 1613,
    "maxX" : 2128,
    "minY" : 493,
    "maxY" : 642,
    "prop" : {
      "x" : 1613,
      "y" : 493,
      "width" : 515,
      "height" : 149
    },
    "textPosition" : {
      "x" : 1829,
      "y" : 546
    },
    "bgColor" : {
      "r" : 250,
      "g" : 240,
      "b" : 240
    },
    "componentIds" : [ 75887, 75888, 75889, 75890 ]
  } ],
  "notes" : [ {
    "id" : 75901,
    "displayName" : "endoplasmic reticulum membrane",
    "renderableClass" : "Note",
    "position" : {
      "x" : 729,
      "y" : 348
    },
    "minX" : 625,
    "maxX" : 833,
    "minY" : 337,
    "maxY" : 359,
    "prop" : {
      "x" : 625,
      "y" : 337,
      "width" : 208,
      "height" : 22
    },
    "textPosition" : {
      "x" : 652,
      "y" : 331
    }
  } ],
  "links" : [ {
    "id" : 75926,
    "renderableClass" : "EntitySetAndEntitySetLink",
    "position" : {
      "x" : 902,
      "y" : 365
    },
    "minX" : 896,
    "maxX" : 908,
    "minY" : 359,
    "maxY" : 371,
    "segments" : [ ],
    "reactionShape" : {
      "a" : {
        "x" : 896,
        "y" : 359
      },
      "b" : {
        "x" : 908,
        "y" : 371
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 902,
        "y" : 365
      }
    },
    "inputs" : [ {
      "id" : 75843
    } ],
    "outputs" : [ {
      "id" : 75838
    } ]
  } ],
  "shadows" : [ {
    "id" : 75937,
    "reactomeId" : 10331679,
    "displayName" : "RHOBTB GTPase Cycle",
    "schemaClass" : "Pathway",
    "renderableClass" : "Shadow",
    "position" : {
      "x" : 624,
      "y" : 2061
    },
    "minX" : 335,
    "maxX" : 913,
    "minY" : 1836,
    "maxY" : 2286,
    "prop" : {
      "x" : 335,
      "y" : 1836,
      "width" : 578,
      "height" : 211
    },
    "points" : [ {
      "x" : 335,
      "y" : 1836
    }, {
      "x" : 913,
      "y" : 1836
    }, {
      "x" : 913,
      "y" : 2286
    }, {
      "x" : 335,
      "y" : 2286
    } ],
    "colour" : "#66aa00"
  }, {
    "id" : 75936,
    "reactomeId" : 10331675,
    "displayName" : "RHOU GTPase cycle",
    "schemaClass" : "Pathway",
    "renderableClass" : "Shadow",
    "position" : {
      "x" : 1262,
      "y" : 2247
    },
    "minX" : 821,
    "maxX" : 1704,
    "minY" : 2047,
    "maxY" : 2447,
    "prop" : {
      "x" : 913,
      "y" : 2047,
      "width" : 791,
      "height" : 222
    },
    "points" : [ {
      "x" : 821,
      "y" : 2047
    }, {
      "x" : 1704,
      "y" : 2047
    }, {
      "x" : 1704,
      "y" : 2447
    }, {
      "x" : 821,
      "y" : 2447
    } ],
    "colour" : "#aaaa11"
  }, {
    "id" : 75939,
    "reactomeId" : 10331843,
    "displayName" : "RHOF GTPase cycle",
    "schemaClass" : "Pathway",
    "renderableClass" : "Shadow",
    "position" : {
      "x" : 3067,
      "y" : 761
    },
    "minX" : 2889,
    "maxX" : 3246,
    "minY" : 616,
    "maxY" : 906,
    "prop" : {
      "x" : 3092,
      "y" : 616,
      "width" : 154,
      "height" : 290
    },
    "points" : [ {
      "x" : 2889,
      "y" : 616
    }, {
      "x" : 3246,
      "y" : 616
    }, {
      "x" : 3246,
      "y" : 906
    }, {
      "x" : 2889,
      "y" : 906
    } ],
    "colour" : "#994499"
  }, {
    "id" : 75938,
    "reactomeId" : 10331683,
    "displayName" : "RHOV GTPase cycle",
    "schemaClass" : "Pathway",
    "renderableClass" : "Shadow",
    "position" : {
      "x" : 702,
      "y" : 2355
    },
    "minX" : 471,
    "maxX" : 934,
    "minY" : 2269,
    "maxY" : 2441,
    "prop" : {
      "x" : 471,
      "y" : 2286,
      "width" : 350,
      "height" : 155
    },
    "points" : [ {
      "x" : 471,
      "y" : 2269
    }, {
      "x" : 934,
      "y" : 2269
    }, {
      "x" : 934,
      "y" : 2441
    }, {
      "x" : 471,
      "y" : 2441
    } ],
    "colour" : "#888888"
  }, {
    "id" : 75941,
    "reactomeId" : 10331847,
    "displayName" : "RND3 GTPase cycle",
    "schemaClass" : "Pathway",
    "renderableClass" : "Shadow",
    "position" : {
      "x" : 2886,
      "y" : 2382
    },
    "minX" : 2634,
    "maxX" : 3138,
    "minY" : 2326,
    "maxY" : 2439,
    "prop" : {
      "x" : 2634,
      "y" : 2326,
      "width" : 504,
      "height" : 113
    },
    "points" : [ {
      "x" : 2634,
      "y" : 2326
    }, {
      "x" : 3138,
      "y" : 2326
    }, {
      "x" : 3138,
      "y" : 2439
    }, {
      "x" : 2634,
      "y" : 2439
    } ],
    "colour" : "#22aa99"
  }, {
    "id" : 75940,
    "reactomeId" : 10331845,
    "displayName" : "RND2 GTPase cycle",
    "schemaClass" : "Pathway",
    "renderableClass" : "Shadow",
    "position" : {
      "x" : 2386,
      "y" : 2390
    },
    "minX" : 2158,
    "maxX" : 2614,
    "minY" : 2340,
    "maxY" : 2441,
    "prop" : {
      "x" : 2158,
      "y" : 2340,
      "width" : 456,
      "height" : 101
    },
    "points" : [ {
      "x" : 2158,
      "y" : 2340
    }, {
      "x" : 2614,
      "y" : 2340
    }, {
      "x" : 2614,
      "y" : 2441
    }, {
      "x" : 2158,
      "y" : 2441
    } ],
    "colour" : "#dd5511"
  }, {
    "id" : 75942,
    "reactomeId" : 10331849,
    "displayName" : "RND1 GTPase cycle",
    "schemaClass" : "Pathway",
    "renderableClass" : "Shadow",
    "position" : {
      "x" : 1927,
      "y" : 2385
    },
    "minX" : 1709,
    "maxX" : 2146,
    "minY" : 2329,
    "maxY" : 2442,
    "prop" : {
      "x" : 1709,
      "y" : 2329,
      "width" : 437,
      "height" : 113
    },
    "points" : [ {
      "x" : 1709,
      "y" : 2329
    }, {
      "x" : 2146,
      "y" : 2329
    }, {
      "x" : 2146,
      "y" : 2442
    }, {
      "x" : 1709,
      "y" : 2442
    } ],
    "colour" : "#999999"
  }, {
    "id" : 75927,
    "reactomeId" : 10331217,
    "displayName" : "RHOQ GTPase cycle",
    "schemaClass" : "Pathway",
    "renderableClass" : "Shadow",
    "position" : {
      "x" : 2877,
      "y" : 1561
    },
    "minX" : 2520,
    "maxX" : 3234,
    "minY" : 1317,
    "maxY" : 1806,
    "prop" : {
      "x" : 2520,
      "y" : 1317,
      "width" : 714,
      "height" : 489
    },
    "points" : [ {
      "x" : 2520,
      "y" : 1317
    }, {
      "x" : 3234,
      "y" : 1317
    }, {
      "x" : 3234,
      "y" : 1806
    }, {
      "x" : 2520,
      "y" : 1806
    } ],
    "colour" : "#4684ee"
  }, {
    "id" : 75929,
    "reactomeId" : 10331659,
    "displayName" : "RHOC GTPase cycle",
    "schemaClass" : "Pathway",
    "renderableClass" : "Shadow",
    "position" : {
      "x" : 475,
      "y" : 1307
    },
    "minX" : -6,
    "maxX" : 957,
    "minY" : 780,
    "maxY" : 1834,
    "prop" : {
      "x" : -6,
      "y" : 1073,
      "width" : 963,
      "height" : 761
    },
    "points" : [ {
      "x" : -6,
      "y" : 780
    }, {
      "x" : 957,
      "y" : 780
    }, {
      "x" : 957,
      "y" : 1834
    }, {
      "x" : -6,
      "y" : 1834
    } ],
    "colour" : "#008000"
  }, {
    "id" : 75928,
    "reactomeId" : 10331625,
    "displayName" : "RHOA GTPase cycle",
    "schemaClass" : "Pathway",
    "renderableClass" : "Shadow",
    "position" : {
      "x" : 600,
      "y" : 187
    },
    "minX" : 178,
    "maxX" : 1023,
    "minY" : 28,
    "maxY" : 347,
    "prop" : {
      "x" : 178,
      "y" : 28,
      "width" : 845,
      "height" : 319
    },
    "points" : [ {
      "x" : 178,
      "y" : 28
    }, {
      "x" : 1023,
      "y" : 28
    }, {
      "x" : 1023,
      "y" : 347
    }, {
      "x" : 178,
      "y" : 347
    } ],
    "colour" : "#dc3912"
  }, {
    "id" : 75931,
    "reactomeId" : 10331663,
    "displayName" : "CDC42 GTPase cycle",
    "schemaClass" : "Pathway",
    "renderableClass" : "Shadow",
    "position" : {
      "x" : 1406,
      "y" : 343
    },
    "minX" : 753,
    "maxX" : 2060,
    "minY" : 40,
    "maxY" : 647,
    "prop" : {
      "x" : 1478,
      "y" : 40,
      "width" : 582,
      "height" : 468
    },
    "points" : [ {
      "x" : 753,
      "y" : 40
    }, {
      "x" : 2060,
      "y" : 40
    }, {
      "x" : 2060,
      "y" : 647
    }, {
      "x" : 753,
      "y" : 647
    } ],
    "colour" : "#4942cc"
  }, {
    "id" : 75930,
    "reactomeId" : 10331661,
    "displayName" : "RAC1 GTPase cycle",
    "schemaClass" : "Pathway",
    "renderableClass" : "Shadow",
    "position" : {
      "x" : 828,
      "y" : 271
    },
    "minX" : 178,
    "maxX" : 1478,
    "minY" : 35,
    "maxY" : 508,
    "prop" : {
      "x" : 178,
      "y" : 35,
      "width" : 1300,
      "height" : 473
    },
    "points" : [ {
      "x" : 178,
      "y" : 35
    }, {
      "x" : 1478,
      "y" : 35
    }, {
      "x" : 1478,
      "y" : 508
    }, {
      "x" : 178,
      "y" : 508
    } ],
    "colour" : "#666666"
  }, {
    "id" : 75933,
    "reactomeId" : 10331667,
    "displayName" : "RHOG GTPase cycle",
    "schemaClass" : "Pathway",
    "renderableClass" : "Shadow",
    "position" : {
      "x" : 378,
      "y" : 495
    },
    "minX" : -10,
    "maxX" : 766,
    "minY" : 234,
    "maxY" : 757,
    "prop" : {
      "x" : -10,
      "y" : 508,
      "width" : 569,
      "height" : 249
    },
    "points" : [ {
      "x" : -10,
      "y" : 234
    }, {
      "x" : 766,
      "y" : 234
    }, {
      "x" : 766,
      "y" : 757
    }, {
      "x" : -10,
      "y" : 757
    } ],
    "colour" : "#d6ae00"
  }, {
    "id" : 75932,
    "reactomeId" : 10331665,
    "displayName" : "RAC2 GTPase cycle",
    "schemaClass" : "Pathway",
    "renderableClass" : "Shadow",
    "position" : {
      "x" : 1825,
      "y" : 555
    },
    "minX" : 559,
    "maxX" : 3092,
    "minY" : 38,
    "maxY" : 1073,
    "prop" : {
      "x" : 2060,
      "y" : 40,
      "width" : 1032,
      "height" : 576
    },
    "points" : [ {
      "x" : 559,
      "y" : 38
    }, {
      "x" : 3092,
      "y" : 38
    }, {
      "x" : 3092,
      "y" : 1073
    }, {
      "x" : 559,
      "y" : 1073
    } ],
    "colour" : "#cb4ac5"
  }, {
    "id" : 75935,
    "reactomeId" : 10331673,
    "displayName" : "RHOH GTPase cycle",
    "schemaClass" : "Pathway",
    "renderableClass" : "Shadow",
    "position" : {
      "x" : 3077,
      "y" : 2053
    },
    "minX" : 2908,
    "maxX" : 3246,
    "minY" : 1865,
    "maxY" : 2241,
    "prop" : {
      "x" : 2908,
      "y" : 1865,
      "width" : 338,
      "height" : 376
    },
    "points" : [ {
      "x" : 2908,
      "y" : 1865
    }, {
      "x" : 3246,
      "y" : 1865
    }, {
      "x" : 3246,
      "y" : 2241
    }, {
      "x" : 2908,
      "y" : 2241
    } ],
    "colour" : "#dd4477"
  }, {
    "id" : 75934,
    "reactomeId" : 10331671,
    "displayName" : "RHOJ GTPase cycle",
    "schemaClass" : "Pathway",
    "renderableClass" : "Shadow",
    "position" : {
      "x" : 3023,
      "y" : 1044
    },
    "minX" : 2838,
    "maxX" : 3208,
    "minY" : 931,
    "maxY" : 1158,
    "prop" : {
      "x" : 2838,
      "y" : 1073,
      "width" : 370,
      "height" : 85
    },
    "points" : [ {
      "x" : 2838,
      "y" : 931
    }, {
      "x" : 3208,
      "y" : 931
    }, {
      "x" : 3208,
      "y" : 1158
    }, {
      "x" : 2838,
      "y" : 1158
    } ],
    "colour" : "#336699"
  } ],
  "minX" : 0,
  "maxX" : 3242,
  "minY" : 0,
  "maxY" : 2445,
  "disease" : false
}