{
  "dbId" : 10331521,
  "stId" : "R-CFA-8878159",
  "speciesName" : "Canis familiaris",
  "nodes" : [ {
    "dbId" : 10239133,
    "stId" : "R-CFA-177104",
    "displayName" : "phospho-Madh3 [nucleoplasm]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 49646,
    "identifier" : "D2YYC0",
    "standardIdentifier" : "uniprot:D2YYC0",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Madh3" ],
    "parents" : [ 10239137 ],
    "children" : [ ]
  }, {
    "dbId" : 10239135,
    "stId" : "R-CFA-177103",
    "displayName" : "SMAD4 [nucleoplasm]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 49646,
    "identifier" : "A0A8I3RR80",
    "standardIdentifier" : "uniprot:A0A8I3RR80",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "SMAD4" ],
    "parents" : [ 10239137 ],
    "children" : [ ]
  }, {
    "dbId" : 10226581,
    "stId" : "R-CFA-9918352",
    "displayName" : "20S core particle [nucleoplasm]",
    "schemaClass" : "Complex",
    "speciesId" : 49646,
    "parents" : [ 10226583 ],
    "children" : [ 10226579, 10226543 ]
  }, {
    "dbId" : 10226583,
    "stId" : "R-CFA-177750",
    "displayName" : "26S proteasome [nucleoplasm]",
    "schemaClass" : "Complex",
    "speciesId" : 49646,
    "diagramIds" : [ 63795 ],
    "parents" : [ ],
    "children" : [ 10226515, 10226581 ]
  }, {
    "dbId" : 10226577,
    "stId" : "R-CFA-174351",
    "displayName" : "PSMA7 [nucleoplasm]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 49646,
    "identifier" : "A0A8I3NW81",
    "standardIdentifier" : "uniprot:A0A8I3NW81",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "PSMA7" ],
    "parents" : [ 10226579 ],
    "children" : [ ]
  }, {
    "dbId" : 10226579,
    "stId" : "R-CFA-9918351",
    "displayName" : "20S CP outer ring [nucleoplasm]",
    "schemaClass" : "Complex",
    "speciesId" : 49646,
    "parents" : [ 10226581 ],
    "children" : [ 10226563, 10226547, 10226577, 10226551, 10226555, 10226559, 10226573 ]
  }, {
    "dbId" : 10226573,
    "stId" : "R-CFA-174314-3",
    "displayName" : "Homologues of PSMA6 [nucleoplasm]",
    "schemaClass" : "DefinedSet",
    "speciesId" : 49646,
    "parents" : [ 10226579 ],
    "children" : [ 10226567, 10226571 ]
  }, {
    "dbId" : 10226318,
    "stId" : "R-CFA-939871",
    "displayName" : "UBA52 [nucleoplasm]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 49646,
    "identifier" : "P63050",
    "standardIdentifier" : "uniprot:P63050",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "UBA52" ],
    "parents" : [ 10226336 ],
    "children" : [ ]
  }, {
    "dbId" : 10226571,
    "stId" : "R-CFA-174314-2",
    "displayName" : "PSMA6 [nucleoplasm]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 49646,
    "identifier" : "A0A8I3PJW0",
    "standardIdentifier" : "uniprot:A0A8I3PJW0",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 10226573 ],
    "children" : [ ]
  }, {
    "dbId" : 10226310,
    "stId" : "R-CFA-939847",
    "displayName" : "RPS27A [nucleoplasm]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 49646,
    "identifier" : "A0A8I3NFB9",
    "standardIdentifier" : "uniprot:A0A8I3NFB9",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "RPS27A" ],
    "parents" : [ 10226336 ],
    "children" : [ ]
  }, {
    "dbId" : 10226567,
    "stId" : "R-CFA-174314",
    "displayName" : "PSMA6 [nucleoplasm]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 49646,
    "identifier" : "A0A8I3N0P1",
    "standardIdentifier" : "uniprot:A0A8I3N0P1",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "PSMA6" ],
    "parents" : [ 10226573 ],
    "children" : [ ]
  }, {
    "dbId" : 10281351,
    "stId" : "R-CFA-69488",
    "displayName" : "TP53 [nucleoplasm]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 49646,
    "identifier" : "E7FIY6",
    "standardIdentifier" : "uniprot:E7FIY6",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 10281716 ],
    "children" : [ ]
  }, {
    "dbId" : 10226816,
    "stId" : "R-CFA-113595",
    "displayName" : "Ub [cytosol]",
    "schemaClass" : "DefinedSet",
    "speciesId" : 49646,
    "diagramIds" : [ 63794 ],
    "parents" : [ ],
    "children" : [ 10226798, 10226792, 10226788, 10226790 ]
  }, {
    "dbId" : 10226306,
    "stId" : "R-CFA-939844",
    "displayName" : "UBA52(1-76) [nucleoplasm]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 49646,
    "identifier" : "A0A8I3PFZ3",
    "standardIdentifier" : "uniprot:A0A8I3PFZ3",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 10226336 ],
    "children" : [ ]
  }, {
    "dbId" : 10226563,
    "stId" : "R-CFA-174340",
    "displayName" : "PSMA5 [nucleoplasm]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 49646,
    "identifier" : "A0A8I3N3S4",
    "standardIdentifier" : "uniprot:A0A8I3N3S4",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "PSMA5" ],
    "parents" : [ 10226579 ],
    "children" : [ ]
  }, {
    "dbId" : 2485002,
    "stId" : "R-ALL-2485002",
    "displayName" : "CoA-SH [nucleoplasm]",
    "schemaClass" : "SimpleEntity",
    "speciesId" : 0,
    "diagramIds" : [ 63774 ],
    "identifier" : "57287",
    "standardIdentifier" : "chebi:57287",
    "referenceType" : "ReferenceMolecule",
    "parents" : [ ],
    "children" : [ ]
  }, {
    "dbId" : 10254003,
    "stId" : "R-CFA-193545",
    "displayName" : "CREBBP [nucleoplasm]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 49646,
    "identifier" : "A0A8I3MJJ8",
    "standardIdentifier" : "uniprot:A0A8I3MJJ8",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "CREBBP" ],
    "parents" : [ 10311201 ],
    "children" : [ ]
  }, {
    "dbId" : 10238893,
    "stId" : "R-CFA-170838",
    "displayName" : "TGFB1 [extracellular region]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 49646,
    "identifier" : "A0A8I3MFB3",
    "standardIdentifier" : "uniprot:A0A8I3MFB3",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "TGFB1" ],
    "parents" : [ 10238895 ],
    "children" : [ ]
  }, {
    "dbId" : 10238895,
    "stId" : "R-CFA-170852",
    "displayName" : "Dimeric TGFB1 [extracellular region]",
    "schemaClass" : "Complex",
    "speciesId" : 49646,
    "diagramIds" : [ 63746 ],
    "parents" : [ ],
    "children" : [ 10238893 ]
  }, {
    "dbId" : 10226336,
    "stId" : "R-CFA-68524",
    "displayName" : "Ub [nucleoplasm]",
    "schemaClass" : "DefinedSet",
    "speciesId" : 49646,
    "diagramIds" : [ 63789 ],
    "parents" : [ ],
    "children" : [ 10226302, 10226318, 10226310, 10226306 ]
  }, {
    "dbId" : 10239137,
    "stId" : "R-CFA-8878153",
    "displayName" : "p-2S-SMAD3:p-2S-SMAD3:SMAD4 [nucleoplasm]",
    "schemaClass" : "Complex",
    "speciesId" : 49646,
    "diagramIds" : [ 63748 ],
    "parents" : [ 10311173 ],
    "children" : [ 10239135, 10239133 ]
  }, {
    "dbId" : 10248411,
    "stId" : "R-CFA-6793669",
    "displayName" : "phospho-p-S166,S188-MDM2 [nucleoplasm]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 49646,
    "identifier" : "P56950",
    "standardIdentifier" : "uniprot:P56950",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 10281704 ],
    "children" : [ ]
  }, {
    "dbId" : 10313683,
    "stId" : "R-CFA-8952123",
    "displayName" : "RUNX3:TP53 tetramer [nucleoplasm]",
    "schemaClass" : "Complex",
    "speciesId" : 49646,
    "diagramIds" : [ 63784 ],
    "parents" : [ ],
    "children" : [ 10281716, 10308938 ]
  }, {
    "dbId" : 10313675,
    "stId" : "R-CFA-8952063",
    "displayName" : "Ac-K94,K171-RUNX3:CBFB:BRD2:CCND1:HDAC4 [nucleoplasm]",
    "schemaClass" : "Complex",
    "speciesId" : 49646,
    "diagramIds" : [ 63781 ],
    "parents" : [ ],
    "children" : [ 10313671, 10248505 ]
  }, {
    "dbId" : 10244810,
    "stId" : "R-CFA-3451168",
    "displayName" : "CTNNB1 [nucleoplasm]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 49646,
    "identifier" : "A0A8I3NUM7",
    "standardIdentifier" : "uniprot:A0A8I3NUM7",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "CTNNB1" ],
    "parents" : [ 10313470 ],
    "children" : [ ]
  }, {
    "dbId" : 10313669,
    "stId" : "R-CFA-8951976",
    "displayName" : "Ac-K94,K171-RUNX3:CBFB:EP300:BRD2 [nucleoplasm]",
    "schemaClass" : "Complex",
    "speciesId" : 49646,
    "diagramIds" : [ 63776 ],
    "parents" : [ ],
    "children" : [ 10313667, 10313546 ]
  }, {
    "dbId" : 10287045,
    "stId" : "R-CFA-3006516",
    "displayName" : "KAT2A [nucleoplasm]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 49646,
    "identifier" : "A0A8I3NA81",
    "standardIdentifier" : "uniprot:A0A8I3NA81",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "KAT2A" ],
    "parents" : [ 10311199 ],
    "children" : [ ]
  }, {
    "dbId" : 10313671,
    "stId" : "R-CFA-8952057",
    "displayName" : "Ac-K94,K171-RUNX3:CBFB:BRD2:CCND1 [nucleoplasm]",
    "schemaClass" : "Complex",
    "speciesId" : 49646,
    "diagramIds" : [ 63778 ],
    "parents" : [ 10313675 ],
    "children" : [ 10313667, 10227204, 10313544 ]
  }, {
    "dbId" : 10313665,
    "stId" : "R-CFA-8951979",
    "displayName" : "Ghost homologue of BRD2 [nucleoplasm]",
    "schemaClass" : "GenomeEncodedEntity",
    "speciesId" : 49646,
    "parents" : [ 10313667 ],
    "children" : [ ]
  }, {
    "dbId" : 10313667,
    "stId" : "R-CFA-8951995",
    "displayName" : "BRD2 homodimer [nucleoplasm]",
    "schemaClass" : "Complex",
    "speciesId" : 49646,
    "parents" : [ 10313671, 10313669 ],
    "children" : [ 10313665 ]
  }, {
    "dbId" : 10313468,
    "stId" : "R-CFA-8951427",
    "displayName" : "TCF7L2,(LEF1,TCF7L1,TCF7) [nucleoplasm]",
    "schemaClass" : "CandidateSet",
    "speciesId" : 49646,
    "parents" : [ 10313470 ],
    "children" : [ 10244915, 10244919, 10244923, 10244927 ]
  }, {
    "dbId" : 10226431,
    "stId" : "R-CFA-174311",
    "displayName" : "PSMD2 [nucleoplasm]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 49646,
    "identifier" : "A0A8I3S6C6",
    "standardIdentifier" : "uniprot:A0A8I3S6C6",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "PSMD2" ],
    "parents" : [ 10226449 ],
    "children" : [ ]
  }, {
    "dbId" : 10311166,
    "stId" : "R-CFA-8878084",
    "displayName" : "ZFHX3 [nucleoplasm]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 49646,
    "diagramIds" : [ 63744 ],
    "identifier" : "A0A8I3N972",
    "standardIdentifier" : "uniprot:A0A8I3N972",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "ZFHX3" ],
    "parents" : [ 10311168 ],
    "children" : [ ]
  }, {
    "dbId" : 10313470,
    "stId" : "R-CFA-8951429",
    "displayName" : "CTNNB1:TCF7L2,(LEF1,TCF7L1,TCF7) [nucleoplasm]",
    "schemaClass" : "Complex",
    "speciesId" : 49646,
    "diagramIds" : [ 63763 ],
    "parents" : [ 10313472 ],
    "children" : [ 10244810, 10313468 ]
  }, {
    "dbId" : 10226427,
    "stId" : "R-CFA-9918361",
    "displayName" : "ADRM1 [nucleoplasm]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 49646,
    "identifier" : "A0A8I3RZD9",
    "standardIdentifier" : "uniprot:A0A8I3RZD9",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "ADRM1" ],
    "parents" : [ 10226471 ],
    "children" : [ ]
  }, {
    "dbId" : 10281716,
    "stId" : "R-CFA-3209194",
    "displayName" : "TP53 Tetramer [nucleoplasm]",
    "schemaClass" : "Complex",
    "speciesId" : 49646,
    "diagramIds" : [ 63783 ],
    "parents" : [ 10313683 ],
    "children" : [ 10281351 ]
  }, {
    "dbId" : 10226423,
    "stId" : "R-CFA-174348",
    "displayName" : "PSMD1 [nucleoplasm]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 49646,
    "identifier" : "A0A8I3PBB2",
    "standardIdentifier" : "uniprot:A0A8I3PBB2",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "PSMD1" ],
    "parents" : [ 10226471 ],
    "children" : [ ]
  }, {
    "dbId" : 10240755,
    "stId" : "R-CFA-178202",
    "displayName" : "SMURF2 [nucleoplasm]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 49646,
    "identifier" : "A0A8I3PG60",
    "standardIdentifier" : "uniprot:A0A8I3PG60",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "SMURF2" ],
    "parents" : [ 10314270 ],
    "children" : [ ]
  }, {
    "dbId" : 10330861,
    "stId" : "R-CFA-1980143",
    "displayName" : "Signaling by NOTCH1",
    "schemaClass" : "Pathway",
    "speciesId" : 49646,
    "diagramIds" : [ 63806 ]
  }, {
    "dbId" : 10281704,
    "stId" : "R-CFA-6804933",
    "displayName" : "p-S166,S188-MDM2 dimer [nucleoplasm]",
    "schemaClass" : "Complex",
    "speciesId" : 49646,
    "diagramIds" : [ 63786 ],
    "parents" : [ 10314248 ],
    "children" : [ 10248411 ]
  }, {
    "dbId" : 10248928,
    "stId" : "R-CFA-1810408",
    "displayName" : "phospho-SRC [plasma membrane]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 49646,
    "diagramIds" : [ 63754 ],
    "identifier" : "A0A8I3SBF9",
    "standardIdentifier" : "uniprot:A0A8I3SBF9",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "SRC" ],
    "parents" : [ 10311799 ],
    "children" : [ ]
  }, {
    "dbId" : 10311197,
    "stId" : "R-CFA-212357",
    "displayName" : "MAML [nucleoplasm]",
    "schemaClass" : "CandidateSet",
    "speciesId" : 49646,
    "parents" : [ 10311201 ],
    "children" : [ 10311187, 10311191, 10311183, 10311195 ]
  }, {
    "dbId" : 10314268,
    "stId" : "R-CFA-3004548",
    "displayName" : "SMURF1 [nucleoplasm]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 49646,
    "identifier" : "A0A8I3N723",
    "standardIdentifier" : "uniprot:A0A8I3N723",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "SMURF1" ],
    "parents" : [ 10314270 ],
    "children" : [ ]
  }, {
    "dbId" : 10311199,
    "stId" : "R-CFA-350078",
    "displayName" : "PCAF [nucleoplasm]",
    "schemaClass" : "CandidateSet",
    "speciesId" : 49646,
    "parents" : [ 10311201 ],
    "children" : [ 10275696, 10287045 ]
  }, {
    "dbId" : 10226463,
    "stId" : "R-CFA-174315",
    "displayName" : "PSMC4 [nucleoplasm]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 49646,
    "identifier" : "A0A8I3MR89",
    "standardIdentifier" : "uniprot:A0A8I3MR89",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "PSMC4" ],
    "parents" : [ 10226469 ],
    "children" : [ ]
  }, {
    "dbId" : 10314270,
    "stId" : "R-CFA-178205",
    "displayName" : "SMURF [nucleoplasm]",
    "schemaClass" : "DefinedSet",
    "speciesId" : 49646,
    "diagramIds" : [ 63798 ],
    "parents" : [ ],
    "children" : [ 10240755, 10314268 ]
  }, {
    "dbId" : 10226457,
    "stId" : "R-CFA-174319",
    "displayName" : "LOC119877792 [nucleoplasm]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 49646,
    "identifier" : "A0A8I3RRR7",
    "standardIdentifier" : "uniprot:A0A8I3RRR7",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "LOC119877792" ],
    "parents" : [ 10226459 ],
    "children" : [ ]
  }, {
    "dbId" : 10266650,
    "stId" : "R-CFA-1253322",
    "displayName" : "YAP1 [nucleoplasm]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 49646,
    "identifier" : "A0A8I3MNH4",
    "standardIdentifier" : "uniprot:A0A8I3MNH4",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 10313512 ],
    "children" : [ ]
  }, {
    "dbId" : 10311195,
    "stId" : "R-CFA-349692",
    "displayName" : "MAMLD1 [nucleoplasm]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 49646,
    "identifier" : "A0A8I3PR31",
    "standardIdentifier" : "uniprot:A0A8I3PR31",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "MAMLD1" ],
    "parents" : [ 10311197 ],
    "children" : [ ]
  }, {
    "dbId" : 10226459,
    "stId" : "R-CFA-9918362",
    "displayName" : "PSMC3:PSMC6 [nucleoplasm]",
    "schemaClass" : "Complex",
    "speciesId" : 49646,
    "parents" : [ 10226471 ],
    "children" : [ 10226453, 10226457 ]
  }, {
    "dbId" : 10314266,
    "stId" : "R-CFA-8952417",
    "displayName" : "PolyUb-RUNX3 [nucleoplasm]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 49646,
    "diagramIds" : [ 63797 ],
    "identifier" : "A0A8I3NME1",
    "standardIdentifier" : "uniprot:A0A8I3NME1",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ ],
    "children" : [ ]
  }, {
    "dbId" : 10226453,
    "stId" : "R-CFA-174313",
    "displayName" : "PSMC3 [nucleoplasm]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 49646,
    "identifier" : "A0A8I3PF55",
    "standardIdentifier" : "uniprot:A0A8I3PF55",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "PSMC3" ],
    "parents" : [ 10226459 ],
    "children" : [ ]
  }, {
    "dbId" : 10311191,
    "stId" : "R-CFA-349689",
    "displayName" : "MAML3 [nucleoplasm]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 49646,
    "identifier" : "A0A8I3PP63",
    "standardIdentifier" : "uniprot:A0A8I3PP63",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "MAML3" ],
    "parents" : [ 10311197 ],
    "children" : [ ]
  }, {
    "dbId" : 10226449,
    "stId" : "R-CFA-9918364",
    "displayName" : "PSMC2:PSMC1:PSMD2 [nucleoplasm]",
    "schemaClass" : "Complex",
    "speciesId" : 49646,
    "parents" : [ 10226471 ],
    "children" : [ 10226447, 10226431 ]
  }, {
    "dbId" : 10314259,
    "stId" : "R-CFA-8952400",
    "displayName" : "PolyUb-K94,K148-RUNX3 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 49646,
    "diagramIds" : [ 63792 ],
    "identifier" : "A0A8I3NME1",
    "standardIdentifier" : "uniprot:A0A8I3NME1",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ ],
    "children" : [ ]
  }, {
    "dbId" : 10311187,
    "stId" : "R-CFA-212353",
    "displayName" : "MAML2 [nucleoplasm]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 49646,
    "identifier" : "A0A8I3NXM7",
    "standardIdentifier" : "uniprot:A0A8I3NXM7",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "MAML2" ],
    "parents" : [ 10311197 ],
    "children" : [ ]
  }, {
    "dbId" : 10226445,
    "stId" : "R-CFA-174332",
    "displayName" : "PSMC2 [nucleoplasm]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 49646,
    "identifier" : "A0A8I3NXK9",
    "standardIdentifier" : "uniprot:A0A8I3NXK9",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "PSMC2" ],
    "parents" : [ 10226447 ],
    "children" : [ ]
  }, {
    "dbId" : 10265358,
    "stId" : "R-CFA-381325",
    "displayName" : "EP300 [nucleoplasm]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 49646,
    "diagramIds" : [ 63799, 63769 ],
    "identifier" : "A0A8I3P730",
    "standardIdentifier" : "uniprot:A0A8I3P730",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "EP300" ],
    "parents" : [ 10311201, 10313546, 10313536 ],
    "children" : [ ]
  }, {
    "dbId" : 10311183,
    "stId" : "R-CFA-212416",
    "displayName" : "MAML1 [nucleoplasm]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 49646,
    "identifier" : "A0A8I3MXZ6",
    "standardIdentifier" : "uniprot:A0A8I3MXZ6",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "MAML1" ],
    "parents" : [ 10311197 ],
    "children" : [ ]
  }, {
    "dbId" : 10314254,
    "stId" : "R-CFA-8952387",
    "displayName" : "PolyUb-K94,K148-RUNX3 [nucleoplasm]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 49646,
    "diagramIds" : [ 63790 ],
    "identifier" : "A0A8I3NME1",
    "standardIdentifier" : "uniprot:A0A8I3NME1",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ ],
    "children" : [ ]
  }, {
    "dbId" : 10226447,
    "stId" : "R-CFA-9918359",
    "displayName" : "PSMC2:PSMC1 [nucleoplasm]",
    "schemaClass" : "Complex",
    "speciesId" : 49646,
    "parents" : [ 10226449 ],
    "children" : [ 10226441, 10226445 ]
  }, {
    "dbId" : 10311177,
    "stId" : "R-CFA-157939",
    "displayName" : "Ghost homologue of NICD1 [nucleoplasm]",
    "schemaClass" : "GenomeEncodedEntity",
    "speciesId" : 49646,
    "parents" : [ 10311179 ],
    "children" : [ ]
  }, {
    "dbId" : 10314248,
    "stId" : "R-CFA-8952373",
    "displayName" : "RUNX3:p-S166,S188-MDM2 dimer [nucleoplasm]",
    "schemaClass" : "Complex",
    "speciesId" : 49646,
    "diagramIds" : [ 63787 ],
    "parents" : [ ],
    "children" : [ 10308938, 10281704 ]
  }, {
    "dbId" : 10226441,
    "stId" : "R-CFA-174338-3",
    "displayName" : "Homologues of PSMC1 [nucleoplasm]",
    "schemaClass" : "DefinedSet",
    "speciesId" : 49646,
    "parents" : [ 10226447 ],
    "children" : [ 10226435, 10226439 ]
  }, {
    "dbId" : 10311179,
    "stId" : "R-CFA-1604460",
    "displayName" : "NICD1:RBPJ:SNW1 [nucleoplasm]",
    "schemaClass" : "Complex",
    "speciesId" : 49646,
    "parents" : [ 10311201 ],
    "children" : [ 10311177, 10247775, 10248525 ]
  }, {
    "dbId" : 10311173,
    "stId" : "R-CFA-8878146",
    "displayName" : "RUNX3:p-2S-SMAD3:p-2S-SMAD3:SMAD4 [nucleoplasm]",
    "schemaClass" : "Complex",
    "speciesId" : 49646,
    "diagramIds" : [ 63749 ],
    "parents" : [ ],
    "children" : [ 10239137, 10308938 ]
  }, {
    "dbId" : 10227204,
    "stId" : "R-CFA-113832",
    "displayName" : "CCND1 [nucleoplasm]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 49646,
    "diagramIds" : [ 63777 ],
    "identifier" : "A0A8I3RYT2",
    "standardIdentifier" : "uniprot:A0A8I3RYT2",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "CCND1" ],
    "parents" : [ 10313671 ],
    "children" : [ ]
  }, {
    "dbId" : 113560,
    "stId" : "R-ALL-113560",
    "displayName" : "Ac-CoA [nucleoplasm]",
    "schemaClass" : "SimpleEntity",
    "speciesId" : 0,
    "diagramIds" : [ 63772 ],
    "identifier" : "57288",
    "standardIdentifier" : "chebi:57288",
    "referenceType" : "ReferenceMolecule",
    "parents" : [ ],
    "children" : [ ]
  }, {
    "dbId" : 10226439,
    "stId" : "R-CFA-174338-2",
    "displayName" : "PSMC1 [nucleoplasm]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 49646,
    "identifier" : "A0A8I3P6M7",
    "standardIdentifier" : "uniprot:A0A8I3P6M7",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 10226441 ],
    "children" : [ ]
  }, {
    "dbId" : 10311168,
    "stId" : "R-CFA-8878120",
    "displayName" : "RUNX3:ZFHX3 [nucleoplasm]",
    "schemaClass" : "Complex",
    "speciesId" : 49646,
    "diagramIds" : [ 63745 ],
    "parents" : [ ],
    "children" : [ 10308938, 10311166 ]
  }, {
    "dbId" : 10313472,
    "stId" : "R-CFA-8951432",
    "displayName" : "RUNX3:CTNNB1:TCF7L2,(LEF1,TCF7L1,TCF7) [nucleoplasm]",
    "schemaClass" : "Complex",
    "speciesId" : 49646,
    "diagramIds" : [ 63764 ],
    "parents" : [ ],
    "children" : [ 10308938, 10313470 ]
  }, {
    "dbId" : 10226435,
    "stId" : "R-CFA-174338",
    "displayName" : "PSMC1 [nucleoplasm]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 49646,
    "identifier" : "A0A8I3NNJ9",
    "standardIdentifier" : "uniprot:A0A8I3NNJ9",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "PSMC1" ],
    "parents" : [ 10226441 ],
    "children" : [ ]
  }, {
    "dbId" : 10226493,
    "stId" : "R-CFA-174309",
    "displayName" : "PSMD7 [nucleoplasm]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 49646,
    "identifier" : "A0A8I3N9G3",
    "standardIdentifier" : "uniprot:A0A8I3N9G3",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "PSMD7" ],
    "parents" : [ 10226495 ],
    "children" : [ ]
  }, {
    "dbId" : 10226495,
    "stId" : "R-CFA-9918357",
    "displayName" : "PSMD7:PSMD12:PSMD13:PSMD14 [nucleoplasm]",
    "schemaClass" : "Complex",
    "speciesId" : 49646,
    "parents" : [ 10226497 ],
    "children" : [ 10226483, 10226487, 10226489, 10226493 ]
  }, {
    "dbId" : 10244927,
    "stId" : "R-CFA-5228649",
    "displayName" : "TCF7L1 [nucleoplasm]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 49646,
    "identifier" : "A0A8I3NXQ2",
    "standardIdentifier" : "uniprot:A0A8I3NXQ2",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "TCF7L1" ],
    "parents" : [ 10313468 ],
    "children" : [ ]
  }, {
    "dbId" : 10308921,
    "stId" : "R-CFA-8865293",
    "displayName" : "CBFB [nucleoplasm]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 49646,
    "diagramIds" : [ 63741 ],
    "identifier" : "A0A8I3NAM5",
    "standardIdentifier" : "uniprot:A0A8I3NAM5",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "CBFB" ],
    "parents" : [ 10313544, 10308940 ],
    "children" : [ ]
  }, {
    "dbId" : 10226489,
    "stId" : "R-CFA-174329",
    "displayName" : "Ghost homologue of PSMD14 [nucleoplasm]",
    "schemaClass" : "GenomeEncodedEntity",
    "speciesId" : 49646,
    "parents" : [ 10226495 ],
    "children" : [ ]
  }, {
    "dbId" : 10248505,
    "stId" : "R-CFA-351581",
    "displayName" : "HDAC4 [nucleoplasm]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 49646,
    "diagramIds" : [ 63780 ],
    "identifier" : "A0A8I3Q401",
    "standardIdentifier" : "uniprot:A0A8I3Q401",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "HDAC4" ],
    "parents" : [ 10313675 ],
    "children" : [ ]
  }, {
    "dbId" : 10244923,
    "stId" : "R-CFA-3299543",
    "displayName" : "TCF7 [nucleoplasm]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 49646,
    "identifier" : "A0A8I3NLG9",
    "standardIdentifier" : "uniprot:A0A8I3NLG9",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "TCF7" ],
    "parents" : [ 10313468 ],
    "children" : [ ]
  }, {
    "dbId" : 10226487,
    "stId" : "R-CFA-174326",
    "displayName" : "PSMD13 [nucleoplasm]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 49646,
    "identifier" : "A0A8I3S6Q5",
    "standardIdentifier" : "uniprot:A0A8I3S6Q5",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "PSMD13" ],
    "parents" : [ 10226495 ],
    "children" : [ ]
  }, {
    "dbId" : 10244919,
    "stId" : "R-CFA-3214972",
    "displayName" : "LEF1 [nucleoplasm]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 49646,
    "identifier" : "A0A8I3Q7N7",
    "standardIdentifier" : "uniprot:A0A8I3Q7N7",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "LEF1" ],
    "parents" : [ 10313468 ],
    "children" : [ ]
  }, {
    "dbId" : 10226483,
    "stId" : "R-CFA-174339",
    "displayName" : "PSMD12 [nucleoplasm]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 49646,
    "identifier" : "A0A8I3PZT2",
    "standardIdentifier" : "uniprot:A0A8I3PZT2",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "PSMD12" ],
    "parents" : [ 10226495 ],
    "children" : [ ]
  }, {
    "dbId" : 10244915,
    "stId" : "R-CFA-201923",
    "displayName" : "TCF7L2 [nucleoplasm]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 49646,
    "identifier" : "A0A8I3Q5H3",
    "standardIdentifier" : "uniprot:A0A8I3Q5H3",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "TCF7L2" ],
    "parents" : [ 10313468 ],
    "children" : [ ]
  }, {
    "dbId" : 10226479,
    "stId" : "R-CFA-174327",
    "displayName" : "PSMD11 [nucleoplasm]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 49646,
    "identifier" : "A0A8I3NN65",
    "standardIdentifier" : "uniprot:A0A8I3NN65",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "PSMD11" ],
    "parents" : [ 10226497 ],
    "children" : [ ]
  }, {
    "dbId" : 10313512,
    "stId" : "R-CFA-8951678",
    "displayName" : "YAP1:TEAD1,TEAD4,(TEAD2,TEAD3) [nucleoplasm]",
    "schemaClass" : "Complex",
    "speciesId" : 49646,
    "diagramIds" : [ 63766 ],
    "parents" : [ 10313514 ],
    "children" : [ 10313510, 10266650 ]
  }, {
    "dbId" : 10226475,
    "stId" : "R-CFA-174318",
    "displayName" : "PSMD8 [nucleoplasm]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 49646,
    "identifier" : "A0A8I3N165",
    "standardIdentifier" : "uniprot:A0A8I3N165",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "PSMD8" ],
    "parents" : [ 10226513 ],
    "children" : [ ]
  }, {
    "dbId" : 10313514,
    "stId" : "R-CFA-8951679",
    "displayName" : "RUNX3:YAP1:TEAD1,TEAD4,(TEAD2,TEAD3) [nucleoplasm]",
    "schemaClass" : "Complex",
    "speciesId" : 49646,
    "diagramIds" : [ 63767 ],
    "parents" : [ ],
    "children" : [ 10308938, 10313512 ]
  }, {
    "dbId" : 113592,
    "stId" : "R-ALL-113592",
    "displayName" : "ATP [cytosol]",
    "schemaClass" : "SimpleEntity",
    "speciesId" : 0,
    "diagramIds" : [ 63758 ],
    "identifier" : "30616",
    "standardIdentifier" : "chebi:30616",
    "referenceType" : "ReferenceMolecule",
    "parents" : [ ],
    "children" : [ ]
  }, {
    "dbId" : 10226469,
    "stId" : "R-CFA-9918349",
    "displayName" : "PSMC4:PSMC5 [nucleoplasm]",
    "schemaClass" : "Complex",
    "speciesId" : 49646,
    "parents" : [ 10226471 ],
    "children" : [ 10226467, 10226463 ]
  }, {
    "dbId" : 29370,
    "stId" : "R-ALL-29370",
    "displayName" : "ADP [cytosol]",
    "schemaClass" : "SimpleEntity",
    "speciesId" : 0,
    "diagramIds" : [ 63760 ],
    "identifier" : "456216",
    "standardIdentifier" : "chebi:456216",
    "referenceType" : "ReferenceMolecule",
    "parents" : [ ],
    "children" : [ ]
  }, {
    "dbId" : 10226471,
    "stId" : "R-CFA-9918353",
    "displayName" : "19S RP base [nucleoplasm]",
    "schemaClass" : "Complex",
    "speciesId" : 49646,
    "parents" : [ 10226515 ],
    "children" : [ 10226449, 10226423, 10226469, 10226459, 10226427 ]
  }, {
    "dbId" : 10313510,
    "stId" : "R-CFA-8951677",
    "displayName" : "TEAD1,TEAD4,(TEAD2,TEAD3) [nucleoplasm]",
    "schemaClass" : "CandidateSet",
    "speciesId" : 49646,
    "parents" : [ 10313512 ],
    "children" : [ 10275686, 10275670, 10275682, 10275678 ]
  }, {
    "dbId" : 10311201,
    "stId" : "R-CFA-1604462",
    "displayName" : "NOTCH1 Coactivator Complex [nucleoplasm]",
    "schemaClass" : "Complex",
    "speciesId" : 49646,
    "diagramIds" : [ 63751 ],
    "parents" : [ 10311203 ],
    "children" : [ 10254003, 10311179, 10265358, 10311199, 10311197 ]
  }, {
    "dbId" : 10311203,
    "stId" : "R-CFA-8878230",
    "displayName" : "RUNX3:NOTCH1 Coactivator Complex [nucleoplasm]",
    "schemaClass" : "Complex",
    "speciesId" : 49646,
    "diagramIds" : [ 63752 ],
    "parents" : [ ],
    "children" : [ 10311201, 10308938 ]
  }, {
    "dbId" : 10226467,
    "stId" : "R-CFA-174312",
    "displayName" : "PSMC5 [nucleoplasm]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 49646,
    "identifier" : "A0A8I3S1Z6",
    "standardIdentifier" : "uniprot:A0A8I3S1Z6",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "PSMC5" ],
    "parents" : [ 10226469 ],
    "children" : [ ]
  }, {
    "dbId" : 10275678,
    "stId" : "R-CFA-2032763",
    "displayName" : "TEAD2 [nucleoplasm]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 49646,
    "identifier" : "A0A8I3MEV0",
    "standardIdentifier" : "uniprot:A0A8I3MEV0",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "TEAD2" ],
    "parents" : [ 10313510 ],
    "children" : [ ]
  }, {
    "dbId" : 10226527,
    "stId" : "R-CFA-174341",
    "displayName" : "PSMB3 [nucleoplasm]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 49646,
    "identifier" : "A0A8I3RXV3",
    "standardIdentifier" : "uniprot:A0A8I3RXV3",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "PSMB3" ],
    "parents" : [ 10226543 ],
    "children" : [ ]
  }, {
    "dbId" : 10247775,
    "stId" : "R-CFA-3008668",
    "displayName" : "RBPJ [nucleoplasm]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 49646,
    "identifier" : "A0A8I3N1T2",
    "standardIdentifier" : "uniprot:A0A8I3N1T2",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "RBPJ" ],
    "parents" : [ 10311179 ],
    "children" : [ ]
  }, {
    "dbId" : 10226523,
    "stId" : "R-CFA-174335",
    "displayName" : "PSMB2 [nucleoplasm]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 49646,
    "identifier" : "A0A8I3NUC6",
    "standardIdentifier" : "uniprot:A0A8I3NUC6",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "PSMB2" ],
    "parents" : [ 10226543 ],
    "children" : [ ]
  }, {
    "dbId" : 10275670,
    "stId" : "R-CFA-2032774",
    "displayName" : "TEAD1 [nucleoplasm]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 49646,
    "identifier" : "A0A8I3PH43",
    "standardIdentifier" : "uniprot:A0A8I3PH43",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "TEAD1" ],
    "parents" : [ 10313510 ],
    "children" : [ ]
  }, {
    "dbId" : 10226519,
    "stId" : "R-CFA-174347",
    "displayName" : "PSMB1 [nucleoplasm]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 49646,
    "identifier" : "A0A8I3PKH4",
    "standardIdentifier" : "uniprot:A0A8I3PKH4",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "PSMB1" ],
    "parents" : [ 10226543 ],
    "children" : [ ]
  }, {
    "dbId" : 10226513,
    "stId" : "R-CFA-9918358",
    "displayName" : "19S RP lid [nucleoplasm]",
    "schemaClass" : "Complex",
    "speciesId" : 49646,
    "parents" : [ 10226515 ],
    "children" : [ 10226475, 10226511 ]
  }, {
    "dbId" : 10226515,
    "stId" : "R-CFA-9918350",
    "displayName" : "19S regulatory particle [nucleoplasm]",
    "schemaClass" : "Complex",
    "speciesId" : 49646,
    "parents" : [ 10226583 ],
    "children" : [ 10226513, 10226471 ]
  }, {
    "dbId" : 10308940,
    "stId" : "R-CFA-8865463",
    "displayName" : "RUNX3:CBFB [nucleoplasm]",
    "schemaClass" : "Complex",
    "speciesId" : 49646,
    "diagramIds" : [ 63742 ],
    "parents" : [ 10313536 ],
    "children" : [ 10308938, 10308921 ]
  }, {
    "dbId" : 10226509,
    "stId" : "R-CFA-9918363",
    "displayName" : "19S RP lid particle 3 [nucleoplasm]",
    "schemaClass" : "Complex",
    "speciesId" : 49646,
    "parents" : [ 10226511 ],
    "children" : [ 10226501, 10226507, 10226505 ]
  }, {
    "dbId" : 10248525,
    "stId" : "R-CFA-351663-3",
    "displayName" : "Homologues of SNW1 [nucleoplasm]",
    "schemaClass" : "DefinedSet",
    "speciesId" : 49646,
    "parents" : [ 10311179 ],
    "children" : [ 10248519, 10248523 ]
  }, {
    "dbId" : 10226511,
    "stId" : "R-CFA-9918356",
    "displayName" : "19S RP lid particle 2 [nucleoplasm]",
    "schemaClass" : "Complex",
    "speciesId" : 49646,
    "parents" : [ 10226513 ],
    "children" : [ 10226497, 10226509 ]
  }, {
    "dbId" : 10226505,
    "stId" : "R-CFA-174316",
    "displayName" : "PSMD6 [nucleoplasm]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 49646,
    "identifier" : "A0A8I3NPX1",
    "standardIdentifier" : "uniprot:A0A8I3NPX1",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "PSMD6" ],
    "parents" : [ 10226509 ],
    "children" : [ ]
  }, {
    "dbId" : 10313544,
    "stId" : "R-CFA-8951964",
    "displayName" : "Ac-K94,K171-RUNX3:CBFB [nucleoplasm]",
    "schemaClass" : "Complex",
    "speciesId" : 49646,
    "parents" : [ 10313671, 10313546 ],
    "children" : [ 10313542, 10308921 ]
  }, {
    "dbId" : 10308938,
    "stId" : "R-CFA-8865393",
    "displayName" : "RUNX3 [nucleoplasm]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 49646,
    "diagramIds" : [ 63740 ],
    "identifier" : "A0A8I3NME1",
    "standardIdentifier" : "uniprot:A0A8I3NME1",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 10314248, 10311203, 10313683, 10311168, 10311173, 10313514, 10313472, 10308940 ],
    "children" : [ ]
  }, {
    "dbId" : 10226507,
    "stId" : "R-CFA-8866665",
    "displayName" : "Ghost homologue of SEM1 [nucleoplasm]",
    "schemaClass" : "GenomeEncodedEntity",
    "speciesId" : 49646,
    "parents" : [ 10226509 ],
    "children" : [ ]
  }, {
    "dbId" : 10313546,
    "stId" : "R-CFA-8951959",
    "displayName" : "Ac-K94,K171-RUNX3:CBFB:EP300 [nucleoplasm]",
    "schemaClass" : "Complex",
    "speciesId" : 49646,
    "diagramIds" : [ 63773 ],
    "parents" : [ 10313669 ],
    "children" : [ 10313544, 10265358 ]
  }, {
    "dbId" : 10248523,
    "stId" : "R-CFA-351663-2",
    "displayName" : "SNW1 [nucleoplasm]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 49646,
    "identifier" : "A0A8I3NNX8",
    "standardIdentifier" : "uniprot:A0A8I3NNX8",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 10248525 ],
    "children" : [ ]
  }, {
    "dbId" : 10226501,
    "stId" : "R-CFA-174328",
    "displayName" : "PSMD3 [nucleoplasm]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 49646,
    "identifier" : "A0A8I3NH42",
    "standardIdentifier" : "uniprot:A0A8I3NH42",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "PSMD3" ],
    "parents" : [ 10226509 ],
    "children" : [ ]
  }, {
    "dbId" : 10313542,
    "stId" : "R-CFA-8951965",
    "displayName" : "Ac-K94,K171-RUNX3 [nucleoplasm]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 49646,
    "identifier" : "A0A8I3NME1",
    "standardIdentifier" : "uniprot:A0A8I3NME1",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 10313544 ],
    "children" : [ ]
  }, {
    "dbId" : 10248519,
    "stId" : "R-CFA-351663",
    "displayName" : "SNW1 [nucleoplasm]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 49646,
    "identifier" : "A0A8I3N2S2",
    "standardIdentifier" : "uniprot:A0A8I3N2S2",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "SNW1" ],
    "parents" : [ 10248525 ],
    "children" : [ ]
  }, {
    "dbId" : 10226497,
    "stId" : "R-CFA-9918360",
    "displayName" : "19S RP Lid Module 1 [nucleoplasm]",
    "schemaClass" : "Complex",
    "speciesId" : 49646,
    "parents" : [ 10226511 ],
    "children" : [ 10226495, 10226479 ]
  }, {
    "dbId" : 10313536,
    "stId" : "R-CFA-8951952",
    "displayName" : "RUNX3:CBFB:EP300 [nucleoplasm]",
    "schemaClass" : "Complex",
    "speciesId" : 49646,
    "diagramIds" : [ 63770 ],
    "parents" : [ ],
    "children" : [ 10265358, 10308940 ]
  }, {
    "dbId" : 10311804,
    "stId" : "R-CFA-8937805",
    "displayName" : "phospho-p-Y-RUNX3 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 49646,
    "diagramIds" : [ 63759 ],
    "identifier" : "A0A8I3NME1",
    "standardIdentifier" : "uniprot:A0A8I3NME1",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ ],
    "children" : [ ]
  }, {
    "dbId" : 10226302,
    "stId" : "R-CFA-939849",
    "displayName" : "RPS27A(1-76) [nucleoplasm]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 49646,
    "identifier" : "A0A8I3NUE4",
    "standardIdentifier" : "uniprot:A0A8I3NUE4",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 10226336 ],
    "children" : [ ]
  }, {
    "dbId" : 10226559,
    "stId" : "R-CFA-174324",
    "displayName" : "PSMA4 [nucleoplasm]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 49646,
    "identifier" : "A0A8I3NP66",
    "standardIdentifier" : "uniprot:A0A8I3NP66",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "PSMA4" ],
    "parents" : [ 10226579 ],
    "children" : [ ]
  }, {
    "dbId" : 10226555,
    "stId" : "R-CFA-174323",
    "displayName" : "PSMA3 [nucleoplasm]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 49646,
    "identifier" : "A0A8I3PDR8",
    "standardIdentifier" : "uniprot:A0A8I3PDR8",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "PSMA3" ],
    "parents" : [ 10226579 ],
    "children" : [ ]
  }, {
    "dbId" : 10311797,
    "stId" : "R-CFA-8937797",
    "displayName" : "RUNX3 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 49646,
    "diagramIds" : [ 63755 ],
    "identifier" : "A0A8I3NME1",
    "standardIdentifier" : "uniprot:A0A8I3NME1",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 10311799 ],
    "children" : [ ]
  }, {
    "dbId" : 10329463,
    "stId" : "R-CFA-170834",
    "displayName" : "Signaling by TGF-beta Receptor Complex",
    "schemaClass" : "Pathway",
    "speciesId" : 49646,
    "diagramIds" : [ 63804 ]
  }, {
    "dbId" : 10311799,
    "stId" : "R-CFA-8937795",
    "displayName" : "MyrG-p-Y419-SRC:RUNX3 [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 49646,
    "diagramIds" : [ 63756 ],
    "parents" : [ ],
    "children" : [ 10248928, 10311797 ]
  }, {
    "dbId" : 10226551,
    "stId" : "R-CFA-174345",
    "displayName" : "PSMA2 [nucleoplasm]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 49646,
    "identifier" : "A0A8I3PCE5",
    "standardIdentifier" : "uniprot:A0A8I3PCE5",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "PSMA2" ],
    "parents" : [ 10226579 ],
    "children" : [ ]
  }, {
    "dbId" : 10275696,
    "stId" : "R-CFA-352430",
    "displayName" : "KAT2B [nucleoplasm]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 49646,
    "identifier" : "A0A8I3P556",
    "standardIdentifier" : "uniprot:A0A8I3P556",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "KAT2B" ],
    "parents" : [ 10311199 ],
    "children" : [ ]
  }, {
    "dbId" : 10226547,
    "stId" : "R-CFA-174333",
    "displayName" : "PSMA1 [nucleoplasm]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 49646,
    "identifier" : "A0A8I3PCT4",
    "standardIdentifier" : "uniprot:A0A8I3PCT4",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "PSMA1" ],
    "parents" : [ 10226579 ],
    "children" : [ ]
  }, {
    "dbId" : 10226541,
    "stId" : "R-CFA-174343",
    "displayName" : "Ghost homologue of PSMB4 [nucleoplasm]",
    "schemaClass" : "GenomeEncodedEntity",
    "speciesId" : 49646,
    "parents" : [ 10226543 ],
    "children" : [ ]
  }, {
    "dbId" : 10226798,
    "stId" : "R-CFA-939188",
    "displayName" : "UBA52 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 49646,
    "identifier" : "P63050",
    "standardIdentifier" : "uniprot:P63050",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "UBA52" ],
    "parents" : [ 10226816 ],
    "children" : [ ]
  }, {
    "dbId" : 10226543,
    "stId" : "R-CFA-9918354",
    "displayName" : "20S CP inner ring [nucleoplasm]",
    "schemaClass" : "Complex",
    "speciesId" : 49646,
    "parents" : [ 10226581 ],
    "children" : [ 10226531, 10226535, 10226519, 10226539, 10226523, 10226527, 10226541 ]
  }, {
    "dbId" : 10226792,
    "stId" : "R-CFA-939214",
    "displayName" : "RPS27A [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 49646,
    "identifier" : "A0A8I3NFB9",
    "standardIdentifier" : "uniprot:A0A8I3NFB9",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "RPS27A" ],
    "parents" : [ 10226816 ],
    "children" : [ ]
  }, {
    "dbId" : 10226539,
    "stId" : "R-CFA-174331",
    "displayName" : "PSMB7 [nucleoplasm]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 49646,
    "identifier" : "A0A8I3N5F1",
    "standardIdentifier" : "uniprot:A0A8I3N5F1",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "PSMB7" ],
    "parents" : [ 10226543 ],
    "children" : [ ]
  }, {
    "dbId" : 10226788,
    "stId" : "R-CFA-939205",
    "displayName" : "RPS27A(1-76) [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 49646,
    "identifier" : "A0A8I3NUE4",
    "standardIdentifier" : "uniprot:A0A8I3NUE4",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 10226816 ],
    "children" : [ ]
  }, {
    "dbId" : 10226790,
    "stId" : "R-CFA-939203",
    "displayName" : "UBA52(1-76) [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 49646,
    "identifier" : "A0A8I3PFZ3",
    "standardIdentifier" : "uniprot:A0A8I3PFZ3",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 10226816 ],
    "children" : [ ]
  }, {
    "dbId" : 10275686,
    "stId" : "R-CFA-2032780",
    "displayName" : "TEAD4 [nucleoplasm]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 49646,
    "identifier" : "A0A8I3PHG5",
    "standardIdentifier" : "uniprot:A0A8I3PHG5",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "TEAD4" ],
    "parents" : [ 10313510 ],
    "children" : [ ]
  }, {
    "dbId" : 10226535,
    "stId" : "R-CFA-174342",
    "displayName" : "PSMB6 [nucleoplasm]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 49646,
    "identifier" : "A0A8I3RT39",
    "standardIdentifier" : "uniprot:A0A8I3RT39",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "PSMB6" ],
    "parents" : [ 10226543 ],
    "children" : [ ]
  }, {
    "dbId" : 10275682,
    "stId" : "R-CFA-2032767",
    "displayName" : "TEAD3 [nucleoplasm]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 49646,
    "identifier" : "A0A8I3MXV6",
    "standardIdentifier" : "uniprot:A0A8I3MXV6",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "TEAD3" ],
    "parents" : [ 10313510 ],
    "children" : [ ]
  }, {
    "dbId" : 10226531,
    "stId" : "R-CFA-174344",
    "displayName" : "PSMB5 [nucleoplasm]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 49646,
    "identifier" : "A0A8I3MNI0",
    "standardIdentifier" : "uniprot:A0A8I3MNI0",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "PSMB5" ],
    "parents" : [ 10226543 ],
    "children" : [ ]
  } ],
  "edges" : [ {
    "dbId" : 10311807,
    "stId" : "R-CFA-8937807",
    "displayName" : "SRC phosphorylates RUNX3",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "preceding" : [ 10311801 ],
    "inputs" : [ 10311799, 113592 ],
    "outputs" : [ 10248928, 29370, 10311804 ],
    "catalysts" : [ 10311799 ],
    "efs" : [ ],
    "diagramIds" : [ 63757 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10311801,
    "stId" : "R-CFA-8937792",
    "displayName" : "RUNX3 binds SRC",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "following" : [ 10311807 ],
    "inputs" : [ 10248928, 10311797 ],
    "outputs" : [ 10311799 ],
    "efs" : [ ],
    "diagramIds" : [ 63753 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10314261,
    "stId" : "R-CFA-8952399",
    "displayName" : "Polyubiquitinated RUNX3 translocates to the cytosol",
    "schemaClass" : "BlackBoxEvent",
    "speciesId" : 0,
    "preceding" : [ 10314257 ],
    "following" : [ 10314263 ],
    "inputs" : [ 10314254 ],
    "outputs" : [ 10314259 ],
    "efs" : [ ],
    "diagramIds" : [ 63791 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10313685,
    "stId" : "R-CFA-8952128",
    "displayName" : "RUNX3 binds TP53",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "preceding" : [ 10311809 ],
    "inputs" : [ 10281716, 10308938 ],
    "outputs" : [ 10313683 ],
    "efs" : [ ],
    "diagramIds" : [ 63782 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10314263,
    "stId" : "R-CFA-8952408",
    "displayName" : "Polyubiquitinated RUNX3 is degraded by the proteasome",
    "schemaClass" : "BlackBoxEvent",
    "speciesId" : 0,
    "preceding" : [ 10314261 ],
    "inputs" : [ 10314259 ],
    "outputs" : [ 10226816 ],
    "catalysts" : [ 10226583 ],
    "efs" : [ ],
    "diagramIds" : [ 63793 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10314257,
    "stId" : "R-CFA-8952382",
    "displayName" : "MDM2 polyubiquitinates RUNX3",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "preceding" : [ 10314250 ],
    "following" : [ 10314261 ],
    "inputs" : [ 10226336, 10314248 ],
    "outputs" : [ 10281704, 10314254 ],
    "catalysts" : [ 10314248 ],
    "efs" : [ ],
    "diagramIds" : [ 63788 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10313549,
    "stId" : "R-CFA-8951966",
    "displayName" : "EP300 acetylates RUNX3",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "preceding" : [ 10313538 ],
    "inputs" : [ 10313536, 113560 ],
    "outputs" : [ 2485002, 10313546 ],
    "catalysts" : [ 10313536 ],
    "efs" : [ ],
    "activators" : [ 10238895 ],
    "diagramIds" : [ 63771 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10313677,
    "stId" : "R-CFA-8952062",
    "displayName" : "CCND1 recruits HDAC4 to RUNX3",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "preceding" : [ 10313673 ],
    "inputs" : [ 10313671, 10248505 ],
    "outputs" : [ 10313675 ],
    "efs" : [ ],
    "diagramIds" : [ 63779 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10313516,
    "stId" : "R-CFA-8951676",
    "displayName" : "RUNX3 binds TEADs and YAP1",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "preceding" : [ 10311809 ],
    "inputs" : [ 10308938, 10313512 ],
    "outputs" : [ 10313514 ],
    "efs" : [ ],
    "diagramIds" : [ 63765 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10308942,
    "stId" : "R-CFA-8865454",
    "displayName" : "CBFB binds RUNX3",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "preceding" : [ 10311809 ],
    "following" : [ 10313538 ],
    "inputs" : [ 10308938, 10308921 ],
    "outputs" : [ 10308940 ],
    "efs" : [ ],
    "diagramIds" : [ 63739 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10313673,
    "stId" : "R-CFA-8952058",
    "displayName" : "CCND1 binds RUNX3 and displaces EP300",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "following" : [ 10313677 ],
    "inputs" : [ 10313669, 10227204 ],
    "outputs" : [ 10313671, 10265358 ],
    "efs" : [ ],
    "diagramIds" : [ 63775 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10314250,
    "stId" : "R-CFA-8952371",
    "displayName" : "MDM2 binds RUNX3",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "preceding" : [ 10311809 ],
    "following" : [ 10314257 ],
    "inputs" : [ 10308938, 10281704 ],
    "outputs" : [ 10314248 ],
    "efs" : [ ],
    "diagramIds" : [ 63785 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10311205,
    "stId" : "R-CFA-8878220",
    "displayName" : "RUNX3 binds the NOTCH1 coactivator complex",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "preceding" : [ 10311809 ],
    "inputs" : [ 10311201, 10308938 ],
    "outputs" : [ 10311203 ],
    "efs" : [ ],
    "diagramIds" : [ 63750 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10311175,
    "stId" : "R-CFA-8878143",
    "displayName" : "RUNX3 binds SMAD3 and SMAD4",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "preceding" : [ 10311809 ],
    "inputs" : [ 10239137, 10308938 ],
    "outputs" : [ 10311173 ],
    "efs" : [ ],
    "diagramIds" : [ 63747 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10311809,
    "stId" : "R-CFA-8937814",
    "displayName" : "RUNX3 translocates to the nucleus",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "following" : [ 10314273, 10314250, 10311205, 10313685, 10311170, 10311175, 10308942, 10313516, 10313474 ],
    "inputs" : [ 10311797 ],
    "outputs" : [ 10308938 ],
    "efs" : [ ],
    "inhibitors" : [ 10248928 ],
    "activators" : [ 10238895 ],
    "diagramIds" : [ 63761 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10314273,
    "stId" : "R-CFA-8952419",
    "displayName" : "SMURFs ubiquitinate RUNX3",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "preceding" : [ 10311809 ],
    "inputs" : [ 10226336, 10308938 ],
    "outputs" : [ 10314266 ],
    "catalysts" : [ 10314270 ],
    "efs" : [ ],
    "inhibitors" : [ 10265358 ],
    "diagramIds" : [ 63796 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10311170,
    "stId" : "R-CFA-8878117",
    "displayName" : "RUNX3 binds ZFHX3",
    "schemaClass" : "BlackBoxEvent",
    "speciesId" : 0,
    "preceding" : [ 10311809 ],
    "inputs" : [ 10308938, 10311166 ],
    "outputs" : [ 10311168 ],
    "efs" : [ ],
    "activators" : [ 10238895 ],
    "diagramIds" : [ 63743 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10313538,
    "stId" : "R-CFA-8951951",
    "displayName" : "RUNX3 binds EP300",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "preceding" : [ 10308942 ],
    "following" : [ 10313549 ],
    "inputs" : [ 10265358, 10308940 ],
    "outputs" : [ 10313536 ],
    "efs" : [ ],
    "diagramIds" : [ 63768 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10313474,
    "stId" : "R-CFA-8951428",
    "displayName" : "RUNX3 binds CTNNB1:TCF7L2,(LEF1,TCF7L1,TCF7)",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "preceding" : [ 10311809 ],
    "inputs" : [ 10308938, 10313470 ],
    "outputs" : [ 10313472 ],
    "efs" : [ ],
    "diagramIds" : [ 63762 ],
    "entityFunctionalStatus" : [ ]
  } ],
  "subpathways" : [ {
    "dbId" : 10331609,
    "stId" : "R-CFA-8951936",
    "displayName" : "RUNX3 regulates p14-ARF",
    "events" : [ 10313549, 10313677, 10313673, 10313538 ]
  }, {
    "dbId" : 10331569,
    "stId" : "R-CFA-8941856",
    "displayName" : "RUNX3 regulates NOTCH signaling",
    "events" : [ 10311205 ]
  }, {
    "dbId" : 10331567,
    "stId" : "R-CFA-8941855",
    "displayName" : "RUNX3 regulates CDKN1A transcription",
    "events" : [ 10313685, 10311175, 10311170 ]
  }, {
    "dbId" : 10331605,
    "stId" : "R-CFA-8951430",
    "displayName" : "RUNX3 regulates WNT signaling",
    "events" : [ 10313474 ]
  }, {
    "dbId" : 10331519,
    "stId" : "R-CFA-8941858",
    "displayName" : "Regulation of RUNX3 expression and activity",
    "events" : [ 10311807, 10308942, 10311801, 10314250, 10314261, 10314263, 10311809, 10314257, 10314273 ]
  }, {
    "dbId" : 10331607,
    "stId" : "R-CFA-8951671",
    "displayName" : "RUNX3 regulates YAP1-mediated transcription",
    "events" : [ 10313516 ]
  } ]
}