{ "dbId" : 10329871, "stId" : "R-CFA-5621481", "speciesName" : "Canis familiaris", "nodes" : [ { "dbId" : 10226844, "stId" : "R-CFA-68796", "displayName" : "PSMD2 [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3S6C6", "standardIdentifier" : "uniprot:A0A8I3S6C6", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "PSMD2" ], "parents" : [ 10226846 ], "children" : [ ] }, { "dbId" : 10226846, "stId" : "R-CFA-9908171", "displayName" : "PSMC2:PSMC1:PSMD2 [cytosol]", "schemaClass" : "Complex", "speciesId" : 49646, "parents" : [ 10226848 ], "children" : [ 10226842, 10226844 ] }, { "dbId" : 10226840, "stId" : "R-CFA-68771", "displayName" : "PSMC2 [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3NXK9", "standardIdentifier" : "uniprot:A0A8I3NXK9", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "PSMC2" ], "parents" : [ 10226842 ], "children" : [ ] }, { "dbId" : 202247, "stId" : "R-ALL-202247", "displayName" : "PI(3,4)P2 [plasma membrane]", "schemaClass" : "SimpleEntity", "speciesId" : 0, "identifier" : "16152", "standardIdentifier" : "chebi:16152", "referenceType" : "ReferenceMolecule", "parents" : [ 202277 ], "children" : [ ] }, { "dbId" : 10226842, "stId" : "R-CFA-9907947", "displayName" : "PSMC2:PSMC1 [cytosol]", "schemaClass" : "Complex", "speciesId" : 49646, "parents" : [ 10226846 ], "children" : [ 10226838, 10226840 ] }, { "dbId" : 10226836, "stId" : "R-CFA-68768-2", "displayName" : "PSMC1 [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3P6M7", "standardIdentifier" : "uniprot:A0A8I3P6M7", "referenceType" : "ReferenceGeneProduct", "parents" : [ 10226838 ], "children" : [ ] }, { "dbId" : 10226838, "stId" : "R-CFA-68768-3", "displayName" : "Homologues of PSMC1 [cytosol]", "schemaClass" : "DefinedSet", "speciesId" : 49646, "parents" : [ 10226842 ], "children" : [ 10226834, 10226836 ] }, { "dbId" : 10226832, "stId" : "R-CFA-9907949", "displayName" : "PSMC4:PSMC5 [cytosol]", "schemaClass" : "Complex", "speciesId" : 49646, "parents" : [ 10226848 ], "children" : [ 10226830, 10226828 ] }, { "dbId" : 10226834, "stId" : "R-CFA-68768", "displayName" : "PSMC1 [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3NNJ9", "standardIdentifier" : "uniprot:A0A8I3NNJ9", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "PSMC1" ], "parents" : [ 10226838 ], "children" : [ ] }, { "dbId" : 10226828, "stId" : "R-CFA-68777", "displayName" : "PSMC4 [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3MR89", "standardIdentifier" : "uniprot:A0A8I3MR89", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "PSMC4" ], "parents" : [ 10226832 ], "children" : [ ] }, { "dbId" : 10226830, "stId" : "R-CFA-68780", "displayName" : "PSMC5 [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3S1Z6", "standardIdentifier" : "uniprot:A0A8I3S1Z6", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "PSMC5" ], "parents" : [ 10226832 ], "children" : [ ] }, { "dbId" : 10226824, "stId" : "R-CFA-5665939", "displayName" : "ADRM1 [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3RZD9", "standardIdentifier" : "uniprot:A0A8I3RZD9", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "ADRM1" ], "parents" : [ 10226848 ], "children" : [ ] }, { "dbId" : 10235016, "stId" : "R-CFA-58268", "displayName" : "SYK [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "diagramIds" : [ 99103 ], "identifier" : "A0A8I3P3G0", "standardIdentifier" : "uniprot:A0A8I3P3G0", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "SYK" ], "parents" : [ 10289677 ], "children" : [ ] }, { "dbId" : 10226826, "stId" : "R-CFA-68786", "displayName" : "PSMD1 [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3PBB2", "standardIdentifier" : "uniprot:A0A8I3PBB2", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "PSMD1" ], "parents" : [ 10226848 ], "children" : [ ] }, { "dbId" : 10226820, "stId" : "R-CFA-68783", "displayName" : "LOC119877792 [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3RRR7", "standardIdentifier" : "uniprot:A0A8I3RRR7", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "LOC119877792" ], "parents" : [ 10226822 ], "children" : [ ] }, { "dbId" : 10226822, "stId" : "R-CFA-9907950", "displayName" : "PSMC3:PSMC6 [cytosol]", "schemaClass" : "Complex", "speciesId" : 49646, "parents" : [ 10226848 ], "children" : [ 10226818, 10226820 ] }, { "dbId" : 10226816, "stId" : "R-CFA-113595", "displayName" : "Ub [cytosol]", "schemaClass" : "DefinedSet", "speciesId" : 49646, "diagramIds" : [ 99082 ], "parents" : [ ], "children" : [ 10226798, 10226792, 10226788, 10226790 ] }, { "dbId" : 10226818, "stId" : "R-CFA-68774", "displayName" : "PSMC3 [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3PF55", "standardIdentifier" : "uniprot:A0A8I3PF55", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "PSMC3" ], "parents" : [ 10226822 ], "children" : [ ] }, { "dbId" : 10226876, "stId" : "R-CFA-9908021", "displayName" : "19S RP lid [cytosol]", "schemaClass" : "Complex", "speciesId" : 49646, "parents" : [ 10226878 ], "children" : [ 10226874, 10226872 ] }, { "dbId" : 10238140, "stId" : "R-CFA-166366", "displayName" : "TRAF6 [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "diagramIds" : [ 99028 ], "identifier" : "A0A8I3P2V4", "standardIdentifier" : "uniprot:A0A8I3P2V4", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "TRAF6" ], "parents" : [ 10289015, 10280767 ], "children" : [ ] }, { "dbId" : 10226878, "stId" : "R-CFA-9908177", "displayName" : "19S regulatory particle [cytosol]", "schemaClass" : "Complex", "speciesId" : 49646, "parents" : [ 10226918 ], "children" : [ 10226848, 10226876 ] }, { "dbId" : 10226872, "stId" : "R-CFA-9908012", "displayName" : "19S RP lid particle 2 [cytosol]", "schemaClass" : "Complex", "speciesId" : 49646, "parents" : [ 10226876 ], "children" : [ 10226870, 10226862 ] }, { "dbId" : 10226874, "stId" : "R-CFA-68808", "displayName" : "PSMD8 [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3N165", "standardIdentifier" : "uniprot:A0A8I3N165", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "PSMD8" ], "parents" : [ 10226876 ], "children" : [ ] }, { "dbId" : 202277, "stId" : "R-ALL-202277", "displayName" : "PIP3, PI(3,4)P2 [plasma membrane]", "schemaClass" : "DefinedSet", "speciesId" : 0, "parents" : [ 10245042 ], "children" : [ 179838, 202247 ] }, { "dbId" : 10226868, "stId" : "R-CFA-8866674", "displayName" : "Ghost homologue of SEM1 [cytosol]", "schemaClass" : "GenomeEncodedEntity", "speciesId" : 49646, "parents" : [ 10226870 ], "children" : [ ] }, { "dbId" : 10226870, "stId" : "R-CFA-9908004", "displayName" : "19S RP lid particle 3 [cytosol]", "schemaClass" : "Complex", "speciesId" : 49646, "parents" : [ 10226872 ], "children" : [ 10226866, 10226864, 10226868 ] }, { "dbId" : 10226864, "stId" : "R-CFA-68798", "displayName" : "PSMD3 [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3NH42", "standardIdentifier" : "uniprot:A0A8I3NH42", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "PSMD3" ], "parents" : [ 10226870 ], "children" : [ ] }, { "dbId" : 10226866, "stId" : "R-CFA-68804", "displayName" : "PSMD6 [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3NPX1", "standardIdentifier" : "uniprot:A0A8I3NPX1", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "PSMD6" ], "parents" : [ 10226870 ], "children" : [ ] }, { "dbId" : 10226860, "stId" : "R-CFA-9907994", "displayName" : "PSMD7:PSMD12:PSMD13:PSMD14 [cytosol]", "schemaClass" : "Complex", "speciesId" : 49646, "parents" : [ 10226862 ], "children" : [ 10226854, 10226852, 10226858, 10226856 ] }, { "dbId" : 10280620, "stId" : "R-CFA-2685705", "displayName" : "NFAT:CaN:CaM [cytosol]", "schemaClass" : "Complex", "speciesId" : 49646, "diagramIds" : [ 99000 ], "parents" : [ ], "children" : [ 10280618, 10275162 ] }, { "dbId" : 10226862, "stId" : "R-CFA-9907993", "displayName" : "19S RP Lid Module 1 [cytosol]", "schemaClass" : "Complex", "speciesId" : 49646, "parents" : [ 10226872 ], "children" : [ 10226850, 10226860 ] }, { "dbId" : 10226856, "stId" : "R-CFA-68806", "displayName" : "PSMD7 [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3N9G3", "standardIdentifier" : "uniprot:A0A8I3N9G3", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "PSMD7" ], "parents" : [ 10226860 ], "children" : [ ] }, { "dbId" : 10280616, "stId" : "R-CFA-2685618", "displayName" : "phospho-NFATC1 [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3MEU0", "standardIdentifier" : "uniprot:A0A8I3MEU0", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "NFATC1" ], "parents" : [ 10280618 ], "children" : [ ] }, { "dbId" : 10226858, "stId" : "R-CFA-68794", "displayName" : "PSMD13 [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3S6Q5", "standardIdentifier" : "uniprot:A0A8I3S6Q5", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "PSMD13" ], "parents" : [ 10226860 ], "children" : [ ] }, { "dbId" : 10280618, "stId" : "R-CFA-2685654", "displayName" : "Dephosphorylated NFAT [cytosol]", "schemaClass" : "DefinedSet", "speciesId" : 49646, "parents" : [ 10280620 ], "children" : [ 10280614, 10280616 ] }, { "dbId" : 10226852, "stId" : "R-CFA-68792", "displayName" : "PSMD12 [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3PZT2", "standardIdentifier" : "uniprot:A0A8I3PZT2", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "PSMD12" ], "parents" : [ 10226860 ], "children" : [ ] }, { "dbId" : 10243236, "stId" : "R-CFA-198294", "displayName" : "phospho-PRKCD [plasma membrane]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3PZJ7", "standardIdentifier" : "uniprot:A0A8I3PZJ7", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "PRKCD" ], "parents" : [ 10288997 ], "children" : [ ] }, { "dbId" : 10226854, "stId" : "R-CFA-68722", "displayName" : "Ghost homologue of PSMD14 [cytosol]", "schemaClass" : "GenomeEncodedEntity", "speciesId" : 49646, "parents" : [ 10226860 ], "children" : [ ] }, { "dbId" : 10280614, "stId" : "R-CFA-2685626", "displayName" : "phospho-NFATC2 [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3PTE6", "standardIdentifier" : "uniprot:A0A8I3PTE6", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "NFATC2" ], "parents" : [ 10280618 ], "children" : [ ] }, { "dbId" : 10226848, "stId" : "R-CFA-9908170", "displayName" : "19S RP base [cytosol]", "schemaClass" : "Complex", "speciesId" : 49646, "parents" : [ 10226878 ], "children" : [ 10226832, 10226822, 10226826, 10226824, 10226846 ] }, { "dbId" : 10226850, "stId" : "R-CFA-68790", "displayName" : "PSMD11 [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3NN65", "standardIdentifier" : "uniprot:A0A8I3NN65", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "PSMD11" ], "parents" : [ 10226862 ], "children" : [ ] }, { "dbId" : 10226908, "stId" : "R-CFA-68734-2", "displayName" : "PSMA6 [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3PJW0", "standardIdentifier" : "uniprot:A0A8I3PJW0", "referenceType" : "ReferenceGeneProduct", "parents" : [ 10226910 ], "children" : [ ] }, { "dbId" : 10245340, "stId" : "R-CFA-202475", "displayName" : "Bcl10 trimer bound to CARMA1 trimer [plasma membrane]", "schemaClass" : "Complex", "speciesId" : 49646, "parents" : [ 10245348 ], "children" : [ 10245331, 10245338 ] }, { "dbId" : 10226910, "stId" : "R-CFA-68734-3", "displayName" : "Homologues of PSMA6 [cytosol]", "schemaClass" : "DefinedSet", "speciesId" : 49646, "parents" : [ 10226914 ], "children" : [ 10226906, 10226908 ] }, { "dbId" : 10253022, "stId" : "R-CFA-211604", "displayName" : "PAK2 [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3QD39", "standardIdentifier" : "uniprot:A0A8I3QD39", "referenceType" : "ReferenceGeneProduct", "parents" : [ 10253034 ], "children" : [ ] }, { "dbId" : 10226904, "stId" : "R-CFA-68732", "displayName" : "PSMA5 [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3N3S4", "standardIdentifier" : "uniprot:A0A8I3N3S4", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "PSMA5" ], "parents" : [ 10226914 ], "children" : [ ] }, { "dbId" : 10253016, "stId" : "R-CFA-162629", "displayName" : "PAK1 [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3NMF7", "standardIdentifier" : "uniprot:A0A8I3NMF7", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "PAK1" ], "parents" : [ 10253034 ], "children" : [ ] }, { "dbId" : 10226906, "stId" : "R-CFA-68734", "displayName" : "PSMA6 [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3N0P1", "standardIdentifier" : "uniprot:A0A8I3N0P1", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "PSMA6" ], "parents" : [ 10226910 ], "children" : [ ] }, { "dbId" : 10263770, "stId" : "R-CFA-976035", "displayName" : "FBXW11 [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3RRK6", "standardIdentifier" : "uniprot:A0A8I3RRK6", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "FBXW11" ], "parents" : [ 10265580 ], "children" : [ ] }, { "dbId" : 10245338, "stId" : "R-CFA-202488", "displayName" : "phospho-BCL10 [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3MNA4", "standardIdentifier" : "uniprot:A0A8I3MNA4", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "BCL10" ], "parents" : [ 10245340 ], "children" : [ ] }, { "dbId" : 10226900, "stId" : "R-CFA-68728", "displayName" : "PSMA3 [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3PDR8", "standardIdentifier" : "uniprot:A0A8I3PDR8", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "PSMA3" ], "parents" : [ 10226914 ], "children" : [ ] }, { "dbId" : 10243285, "stId" : "R-CFA-168104", "displayName" : "CHUK [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3P499", "standardIdentifier" : "uniprot:A0A8I3P499", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "CHUK" ], "parents" : [ 10288905, 10245412, 10245379, 10245377 ], "children" : [ ] }, { "dbId" : 10226902, "stId" : "R-CFA-68730", "displayName" : "PSMA4 [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3NP66", "standardIdentifier" : "uniprot:A0A8I3NP66", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "PSMA4" ], "parents" : [ 10226914 ], "children" : [ ] }, { "dbId" : 10226896, "stId" : "R-CFA-68724", "displayName" : "PSMA1 [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3PCT4", "standardIdentifier" : "uniprot:A0A8I3PCT4", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "PSMA1" ], "parents" : [ 10226914 ], "children" : [ ] }, { "dbId" : 10226898, "stId" : "R-CFA-68726", "displayName" : "PSMA2 [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3PCE5", "standardIdentifier" : "uniprot:A0A8I3PCE5", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "PSMA2" ], "parents" : [ 10226914 ], "children" : [ ] }, { "dbId" : 10240722, "stId" : "R-CFA-65043", "displayName" : "SRC [plasma membrane]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "diagramIds" : [ 98983 ], "identifier" : "A0A8I3SBF9", "standardIdentifier" : "uniprot:A0A8I3SBF9", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "SRC" ], "parents" : [ ], "children" : [ ] }, { "dbId" : 10245331, "stId" : "R-CFA-202445", "displayName" : "CARMA1 trimer [plasma membrane]", "schemaClass" : "Complex", "speciesId" : 49646, "parents" : [ 10245340 ], "children" : [ 10245042, 10245324 ] }, { "dbId" : 10280652, "stId" : "R-CFA-2685702", "displayName" : "BCL10 oligomer [cytosol]", "schemaClass" : "Polymer", "speciesId" : 49646, "parents" : [ 10288955 ], "children" : [ 10245360 ] }, { "dbId" : 10226892, "stId" : "R-CFA-68759", "displayName" : "PSMB7 [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3N5F1", "standardIdentifier" : "uniprot:A0A8I3N5F1", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "PSMB7" ], "parents" : [ 10226894 ], "children" : [ ] }, { "dbId" : 10245324, "stId" : "R-CFA-202438", "displayName" : "phospho-CARD11 [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3NT57", "standardIdentifier" : "uniprot:A0A8I3NT57", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "CARD11" ], "parents" : [ 10245331 ], "children" : [ ] }, { "dbId" : 10280654, "stId" : "R-CFA-2685673", "displayName" : "MALT1 oligomer [cytosol]", "schemaClass" : "Polymer", "speciesId" : 49646, "parents" : [ 10288957 ], "children" : [ 10245344 ] }, { "dbId" : 10226894, "stId" : "R-CFA-9907905", "displayName" : "20S CP inner ring [cytosol]", "schemaClass" : "Complex", "speciesId" : 49646, "parents" : [ 10226916 ], "children" : [ 10226882, 10226880, 10226886, 10226884, 10226890, 10226888, 10226892 ] }, { "dbId" : 10226888, "stId" : "R-CFA-68753", "displayName" : "PSMB5 [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3MNI0", "standardIdentifier" : "uniprot:A0A8I3MNI0", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "PSMB5" ], "parents" : [ 10226894 ], "children" : [ ] }, { "dbId" : 10226890, "stId" : "R-CFA-68756", "displayName" : "PSMB6 [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3RT39", "standardIdentifier" : "uniprot:A0A8I3RT39", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "PSMB6" ], "parents" : [ 10226894 ], "children" : [ ] }, { "dbId" : 10226884, "stId" : "R-CFA-68747", "displayName" : "PSMB3 [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3RXV3", "standardIdentifier" : "uniprot:A0A8I3RXV3", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "PSMB3" ], "parents" : [ 10226894 ], "children" : [ ] }, { "dbId" : 10226886, "stId" : "R-CFA-68750", "displayName" : "Ghost homologue of PSMB4 [cytosol]", "schemaClass" : "GenomeEncodedEntity", "speciesId" : 49646, "parents" : [ 10226894 ], "children" : [ ] }, { "dbId" : 10226880, "stId" : "R-CFA-68738", "displayName" : "PSMB1 [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3PKH4", "standardIdentifier" : "uniprot:A0A8I3PKH4", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "PSMB1" ], "parents" : [ 10226894 ], "children" : [ ] }, { "dbId" : 10226882, "stId" : "R-CFA-68744", "displayName" : "PSMB2 [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3NUC6", "standardIdentifier" : "uniprot:A0A8I3NUC6", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "PSMB2" ], "parents" : [ 10226894 ], "children" : [ ] }, { "dbId" : 10280700, "stId" : "R-CFA-2685624", "displayName" : "PPP3CB [nucleoplasm]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3MW99", "standardIdentifier" : "uniprot:A0A8I3MW99", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "PPP3CB" ], "parents" : [ 10280702 ], "children" : [ ] }, { "dbId" : 10289917, "stId" : "R-CFA-5624465", "displayName" : "phospho-RAF1 [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3PZA0", "standardIdentifier" : "uniprot:A0A8I3PZA0", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "RAF1" ], "parents" : [ 10289919 ], "children" : [ ] }, { "dbId" : 10235133, "stId" : "R-CFA-139950", "displayName" : "Caspase-8 dimer [cytosol]", "schemaClass" : "Complex", "speciesId" : 49646, "parents" : [ 10235135 ], "children" : [ 10235131, 10235129 ] }, { "dbId" : 10280702, "stId" : "R-CFA-2685649", "displayName" : "CaN-catalytic alpha/beta chains [nucleoplasm]", "schemaClass" : "DefinedSet", "speciesId" : 49646, "parents" : [ 10280704 ], "children" : [ 10280698, 10280700 ] }, { "dbId" : 10289919, "stId" : "R-CFA-5624477", "displayName" : "p21 RAS:GTP:p-S338,Y340,Y341-RAF1 [plasma membrane]", "schemaClass" : "Complex", "speciesId" : 49646, "diagramIds" : [ 99131 ], "parents" : [ ], "children" : [ 10239072, 10289917 ] }, { "dbId" : 10288895, "stId" : "R-CFA-5607652", "displayName" : "RELB [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3MRI7", "standardIdentifier" : "uniprot:A0A8I3MRI7", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "RELB" ], "parents" : [ 10288938, 10288897, 10288930, 10288919 ], "children" : [ ] }, { "dbId" : 10235135, "stId" : "R-CFA-2562550", "displayName" : "active caspase-8 [cytosol]", "schemaClass" : "Complex", "speciesId" : 49646, "diagramIds" : [ 99134 ], "parents" : [ 10292018 ], "children" : [ 10235133 ] }, { "dbId" : 10280696, "stId" : "R-CFA-2685704", "displayName" : "CaN alpha regulatory:Ca2+ [nucleoplasm]", "schemaClass" : "Complex", "speciesId" : 49646, "parents" : [ 10280708 ], "children" : [ 10280694, 29496 ] }, { "dbId" : 10289913, "stId" : "R-CFA-5624470", "displayName" : "p21 RAS:GTP:p-S338-RAF1 [plasma membrane]", "schemaClass" : "Complex", "speciesId" : 49646, "diagramIds" : [ 99126 ], "parents" : [ ], "children" : [ 10239072, 10289911 ] }, { "dbId" : 10288889, "stId" : "R-CFA-5607702", "displayName" : "p-S176,S180-IKKA dimer [cytosol]", "schemaClass" : "Complex", "speciesId" : 49646, "parents" : [ 10288891 ], "children" : [ 10238284 ] }, { "dbId" : 10235129, "stId" : "R-CFA-75975", "displayName" : "CASP8 [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "Q38JA9", "standardIdentifier" : "uniprot:Q38JA9", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "CASP8" ], "parents" : [ 10235133 ], "children" : [ ] }, { "dbId" : 10280698, "stId" : "R-CFA-2685599", "displayName" : "PPP3CA [nucleoplasm]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3PS73", "standardIdentifier" : "uniprot:A0A8I3PS73", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "PPP3CA" ], "parents" : [ 10280702 ], "children" : [ ] }, { "dbId" : 10288891, "stId" : "R-CFA-5607681", "displayName" : "Active NIK:p-S176,180-IKKA dimer [cytosol]", "schemaClass" : "Complex", "speciesId" : 49646, "diagramIds" : [ 99065 ], "parents" : [ 10288899, 10288921 ], "children" : [ 10253633, 10288889 ] }, { "dbId" : 10235131, "stId" : "R-CFA-76158", "displayName" : "CASP8 [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "Q38JA9", "standardIdentifier" : "uniprot:Q38JA9", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "CASP8" ], "parents" : [ 10235133 ], "children" : [ ] }, { "dbId" : 10280694, "stId" : "R-CFA-2685631", "displayName" : "PPP3R1 [nucleoplasm]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3PQY6", "standardIdentifier" : "uniprot:A0A8I3PQY6", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "PPP3R1" ], "parents" : [ 10280696 ], "children" : [ ] }, { "dbId" : 10289911, "stId" : "R-CFA-5624469", "displayName" : "phospho-RAF1 [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3PZA0", "standardIdentifier" : "uniprot:A0A8I3PZA0", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "RAF1" ], "parents" : [ 10289913 ], "children" : [ ] }, { "dbId" : 10245360, "stId" : "R-CFA-202447", "displayName" : "BCL10 [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "diagramIds" : [ 99018 ], "identifier" : "A0A8I3MNA4", "standardIdentifier" : "uniprot:A0A8I3MNA4", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "BCL10" ], "parents" : [ 10288976, 10280652 ], "children" : [ ] }, { "dbId" : 10284783, "stId" : "R-CFA-4419894", "displayName" : "UBE2M [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "diagramIds" : [ 99077 ], "identifier" : "A0A8I3MA68", "standardIdentifier" : "uniprot:A0A8I3MA68", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "UBE2M" ], "parents" : [ ], "children" : [ ] }, { "dbId" : 10245353, "stId" : "R-CFA-2685681", "displayName" : "TRAF6 [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3P2V4", "standardIdentifier" : "uniprot:A0A8I3P2V4", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "TRAF6" ], "parents" : [ 10288959, 10245355 ], "children" : [ ] }, { "dbId" : 10264297, "stId" : "R-CFA-947632", "displayName" : "UBA3 [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "diagramIds" : [ 99078 ], "identifier" : "A0A8I3NBH3", "standardIdentifier" : "uniprot:A0A8I3NBH3", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "UBA3" ], "parents" : [ ], "children" : [ ] }, { "dbId" : 10253034, "stId" : "R-CFA-390765", "displayName" : "PAK1,2,3 [cytosol]", "schemaClass" : "DefinedSet", "speciesId" : 49646, "diagramIds" : [ 99127 ], "parents" : [ ], "children" : [ 10253028, 10253016, 10253022 ] }, { "dbId" : 10245355, "stId" : "R-CFA-202456", "displayName" : "Ub-TRAF6 trimer bound to CBM complex [plasma membrane]", "schemaClass" : "Complex", "speciesId" : 49646, "diagramIds" : [ 99091 ], "parents" : [ ], "children" : [ 10245348, 10245353 ] }, { "dbId" : 10226916, "stId" : "R-CFA-9907918", "displayName" : "20S core particle [cytosol]", "schemaClass" : "Complex", "speciesId" : 49646, "parents" : [ 10226918 ], "children" : [ 10226914, 10226894 ] }, { "dbId" : 10245348, "stId" : "R-CFA-202468", "displayName" : "MALT1 trimer bound to Bcl10 and CARMA1 trimer [plasma membrane]", "schemaClass" : "Complex", "speciesId" : 49646, "parents" : [ 10245355 ], "children" : [ 10245346, 10245340 ] }, { "dbId" : 10253028, "stId" : "R-CFA-428457", "displayName" : "PAK3 [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3PNN9", "standardIdentifier" : "uniprot:A0A8I3PNN9", "referenceType" : "ReferenceGeneProduct", "parents" : [ 10253034 ], "children" : [ ] }, { "dbId" : 111736, "stId" : "R-ALL-111736", "displayName" : "Fe3+ [cytosol]", "schemaClass" : "SimpleEntity", "speciesId" : 0, "identifier" : "29034", "standardIdentifier" : "chebi:29034", "referenceType" : "ReferenceMolecule", "parents" : [ 10275118 ], "children" : [ ] }, { "dbId" : 10226918, "stId" : "R-CFA-68819", "displayName" : "26S proteasome [cytosol]", "schemaClass" : "Complex", "speciesId" : 49646, "diagramIds" : [ 99084 ], "parents" : [ ], "children" : [ 10226916, 10226878 ] }, { "dbId" : 10245344, "stId" : "R-CFA-202461", "displayName" : "MALT1 [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "diagramIds" : [ 99023 ], "identifier" : "A0A8I3RR14", "standardIdentifier" : "uniprot:A0A8I3RR14", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "MALT1" ], "parents" : [ 10292018, 10288989, 10280654, 10245346 ], "children" : [ ] }, { "dbId" : 10226912, "stId" : "R-CFA-68736", "displayName" : "PSMA7 [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3NW81", "standardIdentifier" : "uniprot:A0A8I3NW81", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "PSMA7" ], "parents" : [ 10226914 ], "children" : [ ] }, { "dbId" : 179838, "stId" : "R-ALL-179838", "displayName" : "PI(3,4,5)P3 [plasma membrane]", "schemaClass" : "SimpleEntity", "speciesId" : 0, "identifier" : "57836", "standardIdentifier" : "chebi:57836", "referenceType" : "ReferenceMolecule", "parents" : [ 202277 ], "children" : [ ] }, { "dbId" : 10226914, "stId" : "R-CFA-9907911", "displayName" : "20S CP outer ring [cytosol]", "schemaClass" : "Complex", "speciesId" : 49646, "parents" : [ 10226916 ], "children" : [ 10226898, 10226912, 10226896, 10226902, 10226900, 10226904, 10226910 ] }, { "dbId" : 10245346, "stId" : "R-CFA-202487", "displayName" : "MALT1 trimer [cytosol]", "schemaClass" : "Complex", "speciesId" : 49646, "parents" : [ 10245348 ], "children" : [ 10245344 ] }, { "dbId" : 10257949, "stId" : "R-CFA-450264", "displayName" : "TAB3 [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3NMB6", "standardIdentifier" : "uniprot:A0A8I3NMB6", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "TAB3" ], "parents" : [ 10257951 ], "children" : [ ] }, { "dbId" : 10234909, "stId" : "R-CFA-354251", "displayName" : "LYN [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3PUN0", "standardIdentifier" : "uniprot:A0A8I3PUN0", "referenceType" : "ReferenceGeneProduct", "parents" : [ 10289667 ], "children" : [ ] }, { "dbId" : 10257951, "stId" : "R-CFA-446874", "displayName" : "TAB2,TAB3 [cytosol]", "schemaClass" : "DefinedSet", "speciesId" : 49646, "parents" : [ 10288946, 10288969, 10257953 ], "children" : [ 10257945, 10257949 ] }, { "dbId" : 10238488, "stId" : "R-CFA-202463", "displayName" : "UBE2N:UBE2V1 [cytosol]", "schemaClass" : "Complex", "speciesId" : 49646, "diagramIds" : [ 99089, 99045, 99034 ], "parents" : [ ], "children" : [ 10238482, 10238486 ] }, { "dbId" : 10257945, "stId" : "R-CFA-168117", "displayName" : "TAB2 [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3P4Z1", "standardIdentifier" : "uniprot:A0A8I3P4Z1", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "TAB2" ], "parents" : [ 10257951 ], "children" : [ ] }, { "dbId" : 10234905, "stId" : "R-CFA-200917", "displayName" : "FYN [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3P3X1", "standardIdentifier" : "uniprot:A0A8I3P3X1", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "FYN" ], "parents" : [ 10289667 ], "children" : [ ] }, { "dbId" : 10238486, "stId" : "R-CFA-205753", "displayName" : "UBE2V1 [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "E2R2I5", "standardIdentifier" : "uniprot:E2R2I5", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "UBE2V1" ], "parents" : [ 10238488 ], "children" : [ ] }, { "dbId" : 10257943, "stId" : "R-CFA-167923", "displayName" : "TAB1 [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3PLL0", "standardIdentifier" : "uniprot:A0A8I3PLL0", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "TAB1" ], "parents" : [ 10288946, 10288969, 10257953 ], "children" : [ ] }, { "dbId" : 10238480, "stId" : "R-CFA-206072-2", "displayName" : "UBE2N [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3PGB2", "standardIdentifier" : "uniprot:A0A8I3PGB2", "referenceType" : "ReferenceGeneProduct", "parents" : [ 10238482 ], "children" : [ ] }, { "dbId" : 10234897, "stId" : "R-CFA-54715", "displayName" : "FCER1G [plasma membrane]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3QSK6", "standardIdentifier" : "uniprot:A0A8I3QSK6", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "FCER1G" ], "parents" : [ 10234899 ], "children" : [ ] }, { "dbId" : 10238482, "stId" : "R-CFA-206072-3", "displayName" : "Homologues of UBE2N [cytosol]", "schemaClass" : "DefinedSet", "speciesId" : 49646, "parents" : [ 10238488 ], "children" : [ 10238480, 10238478 ] }, { "dbId" : 10257939, "stId" : "R-CFA-168156", "displayName" : "MAP3K7 [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3N7L6", "standardIdentifier" : "uniprot:A0A8I3N7L6", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "MAP3K7" ], "parents" : [ 10257953 ], "children" : [ ] }, { "dbId" : 10234899, "stId" : "R-CFA-210223", "displayName" : "FCERIG dimer [plasma membrane]", "schemaClass" : "Complex", "speciesId" : 49646, "parents" : [ 10289655, 10289661 ], "children" : [ 10234897 ] }, { "dbId" : 10289677, "stId" : "R-CFA-5621149", "displayName" : "pathogens:CLEC6A,CLEC4E:p-Y65,Y76-FCER1G dimer:SYK [plasma membrane]", "schemaClass" : "Complex", "speciesId" : 49646, "diagramIds" : [ 99104 ], "parents" : [ ], "children" : [ 10289643, 10235016 ] }, { "dbId" : 10238478, "stId" : "R-CFA-206072", "displayName" : "UBE2N [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3P6I7", "standardIdentifier" : "uniprot:A0A8I3P6I7", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "UBE2N" ], "parents" : [ 10238482 ], "children" : [ ] }, { "dbId" : 179856, "stId" : "R-ALL-179856", "displayName" : "PI(4,5)P2 [plasma membrane]", "schemaClass" : "SimpleEntity", "speciesId" : 0, "diagramIds" : [ 98988 ], "identifier" : "58456", "standardIdentifier" : "chebi:58456", "referenceType" : "ReferenceMolecule", "parents" : [ ], "children" : [ ] }, { "dbId" : 112275, "stId" : "R-ALL-112275", "displayName" : "DAGs [plasma membrane]", "schemaClass" : "SimpleEntity", "speciesId" : 0, "diagramIds" : [ 98991 ], "identifier" : "18035", "standardIdentifier" : "chebi:18035", "referenceType" : "ReferenceMolecule", "parents" : [ 10288980, 10288997 ], "children" : [ ] }, { "dbId" : 10289672, "stId" : "R-CFA-5621157", "displayName" : "pathogens:CLEC6A,CLEC4E:p-Y65,Y76-FCER1G dimer:p-6Y-SYK:PLCG2 [plasma membrane]", "schemaClass" : "Complex", "speciesId" : 49646, "diagramIds" : [ 99111 ], "parents" : [ ], "children" : [ 10275378, 10289645 ] }, { "dbId" : 10289667, "stId" : "R-CFA-5621132", "displayName" : "FYN, LYN [cytosol]", "schemaClass" : "DefinedSet", "speciesId" : 49646, "diagramIds" : [ 99101, 99132 ], "parents" : [ ], "children" : [ 10234905, 10234909 ] }, { "dbId" : 29356, "stId" : "R-ALL-29356", "displayName" : "H2O [cytosol]", "schemaClass" : "SimpleEntity", "speciesId" : 0, "diagramIds" : [ 98998, 98989 ], "identifier" : "15377", "standardIdentifier" : "chebi:15377", "referenceType" : "ReferenceMolecule", "parents" : [ ], "children" : [ ] }, { "dbId" : 10275378, "stId" : "R-CFA-984806", "displayName" : "PLCG2 [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3NZG2", "standardIdentifier" : "uniprot:A0A8I3NZG2", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "PLCG2" ], "parents" : [ 10289672 ], "children" : [ ] }, { "dbId" : 2685584, "stId" : "R-ALL-2685584", "displayName" : "Fe3+ [nucleoplasm]", "schemaClass" : "SimpleEntity", "speciesId" : 0, "identifier" : "29034", "standardIdentifier" : "chebi:29034", "referenceType" : "ReferenceMolecule", "parents" : [ 10280704 ], "children" : [ ] }, { "dbId" : 29370, "stId" : "R-ALL-29370", "displayName" : "ADP [cytosol]", "schemaClass" : "SimpleEntity", "speciesId" : 0, "diagramIds" : [ 99057, 99107, 99125, 99013, 98982, 99112, 99064, 99051, 99099, 99130, 99071 ], "identifier" : "456216", "standardIdentifier" : "chebi:456216", "referenceType" : "ReferenceMolecule", "parents" : [ ], "children" : [ ] }, { "dbId" : 29372, "stId" : "R-ALL-29372", "displayName" : "Pi [cytosol]", "schemaClass" : "SimpleEntity", "speciesId" : 0, "diagramIds" : [ 99001 ], "identifier" : "43474", "standardIdentifier" : "chebi:43474", "referenceType" : "ReferenceMolecule", "parents" : [ ], "children" : [ ] }, { "dbId" : 10257953, "stId" : "R-CFA-446878", "displayName" : "TAK1 complex [cytosol]", "schemaClass" : "Complex", "speciesId" : 49646, "diagramIds" : [ 99040 ], "parents" : [ 10289047 ], "children" : [ 10257939, 10257943, 10257951 ] }, { "dbId" : 9038391, "stId" : "R-ALL-9038391", "displayName" : "TDM,alpha-mannan [plasma membrane]", "schemaClass" : "DefinedSet", "speciesId" : 0, "diagramIds" : [ 99093 ], "parents" : [ 10289643, 10289663 ], "children" : [ 5621138, 5621136 ] }, { "dbId" : 111294, "stId" : "R-ALL-111294", "displayName" : "PPi [cytosol]", "schemaClass" : "SimpleEntity", "speciesId" : 0, "diagramIds" : [ 99048, 99036 ], "identifier" : "33019", "standardIdentifier" : "chebi:33019", "chebiIdentifier" : "chebi:33019", "referenceType" : "ReferenceMolecule", "parents" : [ ], "children" : [ ] }, { "dbId" : 10239070, "stId" : "R-CFA-9649715", "displayName" : "mature p21 RAS [plasma membrane]", "schemaClass" : "DefinedSet", "speciesId" : 49646, "parents" : [ 10239072 ], "children" : [ 10239058, 10239065, 10239052 ] }, { "dbId" : 10239065, "stId" : "R-CFA-9647912", "displayName" : "HRAS [plasma membrane]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3Q1I3", "standardIdentifier" : "uniprot:A0A8I3Q1I3", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "HRAS" ], "parents" : [ 10239070 ], "children" : [ ] }, { "dbId" : 10239058, "stId" : "R-CFA-9647910", "displayName" : "NRAS [plasma membrane]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3PSP7", "standardIdentifier" : "uniprot:A0A8I3PSP7", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "NRAS" ], "parents" : [ 10239070 ], "children" : [ ] }, { "dbId" : 10239052, "stId" : "R-CFA-9647915", "displayName" : "KRAS [plasma membrane]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3PZB5", "standardIdentifier" : "uniprot:A0A8I3PZB5", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "KRAS" ], "parents" : [ 10239070 ], "children" : [ ] }, { "dbId" : 10234954, "stId" : "R-CFA-141096", "displayName" : "phospho-FCER1G [plasma membrane]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3QSK6", "standardIdentifier" : "uniprot:A0A8I3QSK6", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "FCER1G" ], "parents" : [ 10289639 ], "children" : [ ] }, { "dbId" : 10233414, "stId" : "R-CFA-61459", "displayName" : "PDPK1 [plasma membrane]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3MQX7", "standardIdentifier" : "uniprot:A0A8I3MQX7", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "PDPK1" ], "parents" : [ 10245042 ], "children" : [ ] }, { "dbId" : 10228807, "stId" : "R-CFA-9016707", "displayName" : "CALM1 [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3PNY6", "standardIdentifier" : "uniprot:A0A8I3PNY6", "referenceType" : "ReferenceGeneProduct", "parents" : [ 10234116 ], "children" : [ ] }, { "dbId" : 10226798, "stId" : "R-CFA-939188", "displayName" : "UBA52 [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "P63050", "standardIdentifier" : "uniprot:P63050", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "UBA52" ], "parents" : [ 10226816 ], "children" : [ ] }, { "dbId" : 29426, "stId" : "R-ALL-29426", "displayName" : "Zn2+ [cytosol]", "schemaClass" : "SimpleEntity", "speciesId" : 0, "identifier" : "29105", "standardIdentifier" : "chebi:29105", "referenceType" : "ReferenceMolecule", "parents" : [ 10275118 ], "children" : [ ] }, { "dbId" : 10226792, "stId" : "R-CFA-939214", "displayName" : "RPS27A [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3NFB9", "standardIdentifier" : "uniprot:A0A8I3NFB9", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "RPS27A" ], "parents" : [ 10226816 ], "children" : [ ] }, { "dbId" : 10226788, "stId" : "R-CFA-939205", "displayName" : "RPS27A(1-76) [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3NUE4", "standardIdentifier" : "uniprot:A0A8I3NUE4", "referenceType" : "ReferenceGeneProduct", "parents" : [ 10226816 ], "children" : [ ] }, { "dbId" : 10226790, "stId" : "R-CFA-939203", "displayName" : "UBA52(1-76) [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3PFZ3", "standardIdentifier" : "uniprot:A0A8I3PFZ3", "referenceType" : "ReferenceGeneProduct", "parents" : [ 10226816 ], "children" : [ ] }, { "dbId" : 2186970, "stId" : "R-ALL-2186970", "displayName" : "1,3-beta-D-glucan [extracellular region]", "schemaClass" : "SimpleEntity", "speciesId" : 0, "identifier" : "37671", "standardIdentifier" : "chebi:37671", "referenceType" : "ReferenceMolecule", "parents" : [ 10289023, 10289028 ], "children" : [ ] }, { "dbId" : 10239072, "stId" : "R-CFA-109783", "displayName" : "p21 RAS:GTP [plasma membrane]", "schemaClass" : "Complex", "speciesId" : 49646, "diagramIds" : [ 99120 ], "parents" : [ 10289919, 10289913, 10289923 ], "children" : [ 10239070, 29438 ] }, { "dbId" : 29438, "stId" : "R-ALL-29438", "displayName" : "GTP [cytosol]", "schemaClass" : "SimpleEntity", "speciesId" : 0, "identifier" : "37565", "standardIdentifier" : "chebi:37565", "referenceType" : "ReferenceMolecule", "parents" : [ 10239072 ], "children" : [ ] }, { "dbId" : 10289047, "stId" : "R-CFA-5607672", "displayName" : "p-T231-CARD9:BCL10:MALT1:K63polyUb-TRAF6 oligomers:TRIKA2 [plasma membrane]", "schemaClass" : "Complex", "speciesId" : 49646, "diagramIds" : [ 99041 ], "parents" : [ ], "children" : [ 10288961, 10257953 ] }, { "dbId" : 10242455, "stId" : "R-CFA-168114", "displayName" : "IKBKB [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3N4F2", "standardIdentifier" : "uniprot:A0A8I3N4F2", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "IKBKB" ], "parents" : [ 10245377 ], "children" : [ ] }, { "dbId" : 10289040, "stId" : "R-CFA-5607631", "displayName" : "phospho-PLCG2 [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "diagramIds" : [ 98985 ], "identifier" : "A0A8I3NZG2", "standardIdentifier" : "uniprot:A0A8I3NZG2", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "PLCG2" ], "parents" : [ 10289647 ], "children" : [ ] }, { "dbId" : 10289036, "stId" : "R-CFA-561194", "displayName" : "CARD9 [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "diagramIds" : [ 99015 ], "identifier" : "A0A8I3N256", "standardIdentifier" : "uniprot:A0A8I3N256", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "CARD9" ], "parents" : [ ], "children" : [ ] }, { "dbId" : 10289032, "stId" : "R-CFA-5607674", "displayName" : "p-T231-CARD9:BCL10:MALT1:TRAF6 oligomers [plasma membrane]", "schemaClass" : "Complex", "speciesId" : 49646, "diagramIds" : [ 99031 ], "parents" : [ ], "children" : [ 10280767, 10288957 ] }, { "dbId" : 10289028, "stId" : "R-CFA-5607677", "displayName" : "1,3-beta-D-glucan:p-Y15-CLEC7A [plasma membrane]", "schemaClass" : "Complex", "speciesId" : 49646, "diagramIds" : [ 98981 ], "parents" : [ ], "children" : [ 10289026, 2186970 ] }, { "dbId" : 10289026, "stId" : "R-CFA-5607641", "displayName" : "phospho-CLEC7A [plasma membrane]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3QCX4", "standardIdentifier" : "uniprot:A0A8I3QCX4", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "CLEC7A" ], "parents" : [ 10289028 ], "children" : [ ] }, { "dbId" : 10238339, "stId" : "R-CFA-177674", "displayName" : "NFKB2 [nucleoplasm]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3PK60", "standardIdentifier" : "uniprot:A0A8I3PK60", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "NFKB2" ], "parents" : [ 10289004 ], "children" : [ ] }, { "dbId" : 76577, "stId" : "R-ALL-76577", "displayName" : "AMP [cytosol]", "schemaClass" : "SimpleEntity", "speciesId" : 0, "diagramIds" : [ 99047, 99037 ], "identifier" : "456215", "standardIdentifier" : "chebi:456215", "referenceType" : "ReferenceMolecule", "parents" : [ ], "children" : [ ] }, { "dbId" : 74016, "stId" : "R-ALL-74016", "displayName" : "Ca2+ [cytosol]", "schemaClass" : "SimpleEntity", "speciesId" : 0, "diagramIds" : [ 98994 ], "identifier" : "29108", "standardIdentifier" : "chebi:29108", "referenceType" : "ReferenceMolecule", "parents" : [ 10275158, 10234116 ], "children" : [ ] }, { "dbId" : 200493, "stId" : "R-ALL-200493", "displayName" : "Zn2+ [nucleoplasm]", "schemaClass" : "SimpleEntity", "speciesId" : 0, "identifier" : "29105", "standardIdentifier" : "chebi:29105", "referenceType" : "ReferenceMolecule", "parents" : [ 10280704 ], "children" : [ ] }, { "dbId" : 10245042, "stId" : "R-CFA-202311", "displayName" : "PDK1:PIP2,PIP3 [plasma membrane]", "schemaClass" : "Complex", "speciesId" : 49646, "parents" : [ 10245331 ], "children" : [ 10233414, 202277 ] }, { "dbId" : 29496, "stId" : "R-ALL-29496", "displayName" : "Ca2+ [nucleoplasm]", "schemaClass" : "SimpleEntity", "speciesId" : 0, "identifier" : "29108", "standardIdentifier" : "chebi:29108", "referenceType" : "ReferenceMolecule", "parents" : [ 10257198, 10280696 ], "children" : [ ] }, { "dbId" : 10238426, "stId" : "R-CFA-939176", "displayName" : "UBA52 [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "P63050", "standardIdentifier" : "uniprot:P63050", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "UBA52" ], "parents" : [ 10238452 ], "children" : [ ] }, { "dbId" : 10238417, "stId" : "R-CFA-939224", "displayName" : "RPS27A [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3NFB9", "standardIdentifier" : "uniprot:A0A8I3NFB9", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "RPS27A" ], "parents" : [ 10238452 ], "children" : [ ] }, { "dbId" : 10238414, "stId" : "R-CFA-939169", "displayName" : "Ub-63-UBA52(1-76) [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3PFZ3", "standardIdentifier" : "uniprot:A0A8I3PFZ3", "referenceType" : "ReferenceGeneProduct", "parents" : [ 10238452 ], "children" : [ ] }, { "dbId" : 10238411, "stId" : "R-CFA-939248", "displayName" : "Ub-63-RPS27A(1-76) [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3NUE4", "standardIdentifier" : "uniprot:A0A8I3NUE4", "referenceType" : "ReferenceGeneProduct", "parents" : [ 10238452 ], "children" : [ ] }, { "dbId" : 114520, "stId" : "R-ALL-114520", "displayName" : "I(1,4,5)P3 [cytosol]", "schemaClass" : "SimpleEntity", "speciesId" : 0, "diagramIds" : [ 98990 ], "identifier" : "203600", "standardIdentifier" : "chebi:203600", "referenceType" : "ReferenceMolecule", "parents" : [ ], "children" : [ ] }, { "dbId" : 10289661, "stId" : "R-CFA-5621137", "displayName" : "CLEC4E:FCER1G dimer [plasma membrane]", "schemaClass" : "Complex", "speciesId" : 49646, "diagramIds" : [ 99094 ], "parents" : [ 10289663 ], "children" : [ 10234899, 10289637 ] }, { "dbId" : 10289663, "stId" : "R-CFA-5621144", "displayName" : "CLEC4E:FCER1G dimer:TDM,alpha-mannan [plasma membrane]", "schemaClass" : "Complex", "speciesId" : 49646, "diagramIds" : [ 99095, 99097 ], "parents" : [ ], "children" : [ 9038391, 10289661 ] }, { "dbId" : 10289657, "stId" : "R-CFA-5621151", "displayName" : "CLEC4D:FCER1G dimer:TDM [plasma membrane]", "schemaClass" : "Complex", "speciesId" : 49646, "diagramIds" : [ 99118 ], "parents" : [ ], "children" : [ 10289655, 5621138 ] }, { "dbId" : 10238452, "stId" : "R-CFA-450143", "displayName" : "K63-Ub [cytosol]", "schemaClass" : "DefinedSet", "speciesId" : 49646, "parents" : [ 10238454 ], "children" : [ 10238417, 10238411, 10238426, 10238414 ] }, { "dbId" : 10289653, "stId" : "R-CFA-1472859", "displayName" : "CLEC4D [plasma membrane]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3PH48", "standardIdentifier" : "uniprot:A0A8I3PH48", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "CLEC4D" ], "parents" : [ 10289655 ], "children" : [ ] }, { "dbId" : 10238454, "stId" : "R-CFA-450152", "displayName" : "K63polyUb [cytosol]", "schemaClass" : "Polymer", "speciesId" : 49646, "diagramIds" : [ 99088, 99044, 99035 ], "parents" : [ ], "children" : [ 10238452 ] }, { "dbId" : 10289655, "stId" : "R-CFA-5621148", "displayName" : "CLEC4D:FCER1G dimer [plasma membrane]", "schemaClass" : "Complex", "speciesId" : 49646, "diagramIds" : [ 99116 ], "parents" : [ 10289657 ], "children" : [ 10234899, 10289653 ] }, { "dbId" : 10265580, "stId" : "R-CFA-1168592", "displayName" : "CUL1:FBXW11:SKP1 [cytosol]", "schemaClass" : "Complex", "speciesId" : 49646, "diagramIds" : [ 99074 ], "parents" : [ 10288923 ], "children" : [ 10239766, 10263770, 10239768 ] }, { "dbId" : 10289645, "stId" : "R-CFA-5621160", "displayName" : "pathogens:CLEC6A,CLEC4E:p-Y65,Y76-FCER1G dimer:p-6Y-SYK [plasma membrane]", "schemaClass" : "Complex", "speciesId" : 49646, "diagramIds" : [ 99108 ], "parents" : [ 10289647, 10289672 ], "children" : [ 10264902, 10289643 ] }, { "dbId" : 10289647, "stId" : "R-CFA-5621158", "displayName" : "pathogens:CLEC6A,CLEC4E:p-Y65,Y76-FCER1G dimer:p-6Y-SYK:p-Y753,Y759-PLCG2 [plasma membrane]", "schemaClass" : "Complex", "speciesId" : 49646, "diagramIds" : [ 99113 ], "parents" : [ ], "children" : [ 10289040, 10289645 ] }, { "dbId" : 10289641, "stId" : "R-CFA-5621142", "displayName" : "CLEC4E:p-Y65,Y76-FCER1G dimer [plasma membrane]", "schemaClass" : "Complex", "speciesId" : 49646, "parents" : [ 10289643 ], "children" : [ 10289639, 10289637 ] }, { "dbId" : 10289643, "stId" : "R-CFA-5621133", "displayName" : "CLEC4E:p-Y65,Y76-FCER1G dimer:TDM,alpha-mannan [plasma membrane]", "schemaClass" : "Complex", "speciesId" : 49646, "diagramIds" : [ 99100 ], "parents" : [ 10289677, 10289645 ], "children" : [ 9038391, 10289641 ] }, { "dbId" : 10289637, "stId" : "R-CFA-2130735", "displayName" : "LOC611538 [plasma membrane]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3PLZ5", "standardIdentifier" : "uniprot:A0A8I3PLZ5", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "LOC611538" ], "parents" : [ 10289641, 10289661 ], "children" : [ ] }, { "dbId" : 10289639, "stId" : "R-CFA-5621141", "displayName" : "p-Y65,Y76-FCER1G dimer [plasma membrane]", "schemaClass" : "Complex", "speciesId" : 49646, "parents" : [ 10289641 ], "children" : [ 10234954 ] }, { "dbId" : 10239768, "stId" : "R-CFA-174230", "displayName" : "CUL1 [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3NP41", "standardIdentifier" : "uniprot:A0A8I3NP41", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "CUL1" ], "parents" : [ 10265580 ], "children" : [ ] }, { "dbId" : 10288921, "stId" : "R-CFA-5607698", "displayName" : "Active NIK:p-S176,180-IKKA dimer:p-7S-p100:RELB [cytosol]", "schemaClass" : "Complex", "speciesId" : 49646, "diagramIds" : [ 99072 ], "parents" : [ 10288923 ], "children" : [ 10288919, 10288891 ] }, { "dbId" : 10258202, "stId" : "R-CFA-449030", "displayName" : "IL1B [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "diagramIds" : [ 99141 ], "identifier" : "A0A8I3NVB6", "standardIdentifier" : "uniprot:A0A8I3NVB6", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "IL1B" ], "parents" : [ ], "children" : [ ] }, { "dbId" : 10288923, "stId" : "R-CFA-5607693", "displayName" : "Active NIK:p-176,S180-IKKA dimer:p-7S-p100:SCF-beta-TRCP [cytosol]", "schemaClass" : "Complex", "speciesId" : 49646, "diagramIds" : [ 99075 ], "parents" : [ ], "children" : [ 10288921, 10265580 ] }, { "dbId" : 10288917, "stId" : "R-CFA-5607629", "displayName" : "phospho-NFKB2 [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3PK60", "standardIdentifier" : "uniprot:A0A8I3PK60", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "NFKB2" ], "parents" : [ 10288919 ], "children" : [ ] }, { "dbId" : 10239766, "stId" : "R-CFA-174150", "displayName" : "SKP1 [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3P1G9", "standardIdentifier" : "uniprot:A0A8I3P1G9", "referenceType" : "ReferenceGeneProduct", "parents" : [ 10265580 ], "children" : [ ] }, { "dbId" : 10288919, "stId" : "R-CFA-5607686", "displayName" : "p-7S-p100:RELB [cytosol]", "schemaClass" : "Complex", "speciesId" : 49646, "parents" : [ 10288921 ], "children" : [ 10288917, 10288895 ] }, { "dbId" : 10235153, "stId" : "R-CFA-51291", "displayName" : "PPP3R1 [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3PQY6", "standardIdentifier" : "uniprot:A0A8I3PQY6", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "PPP3R1" ], "parents" : [ 10275158, 10275120 ], "children" : [ ] }, { "dbId" : 10258194, "stId" : "R-CFA-449046", "displayName" : "IL1B [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "diagramIds" : [ 99142 ], "identifier" : "A0A8I3NVB6", "standardIdentifier" : "uniprot:A0A8I3NVB6", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "IL1B" ], "parents" : [ ], "children" : [ ] }, { "dbId" : 10280716, "stId" : "R-CFA-2685690", "displayName" : "NFAT:CaN:CaM [nucleoplasm]", "schemaClass" : "Complex", "speciesId" : 49646, "diagramIds" : [ 99003 ], "parents" : [ ], "children" : [ 10280708, 10280714 ] }, { "dbId" : 10280712, "stId" : "R-CFA-2025935", "displayName" : "phospho-NFATC1 [nucleoplasm]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3MEU0", "standardIdentifier" : "uniprot:A0A8I3MEU0", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "NFATC1" ], "parents" : [ 10280714 ], "children" : [ ] }, { "dbId" : 10258184, "stId" : "R-CFA-448689", "displayName" : "IL1B [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "diagramIds" : [ 99140 ], "identifier" : "A0A8I3NVB6", "standardIdentifier" : "uniprot:A0A8I3NVB6", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "IL1B" ], "parents" : [ ], "children" : [ ] }, { "dbId" : 10288905, "stId" : "R-CFA-5607705", "displayName" : "IKKA dimer [cytosol]", "schemaClass" : "Complex", "speciesId" : 49646, "diagramIds" : [ 99062 ], "parents" : [ ], "children" : [ 10243285 ] }, { "dbId" : 10280714, "stId" : "R-CFA-2025852", "displayName" : "Dephosphorylated NFATC1,2,3 [nucleoplasm]", "schemaClass" : "DefinedSet", "speciesId" : 49646, "parents" : [ 10280716 ], "children" : [ 10280710, 10280712 ] }, { "dbId" : 10234116, "stId" : "R-CFA-74294", "displayName" : "CALM1:4xCa2+ [cytosol]", "schemaClass" : "Complex", "speciesId" : 49646, "diagramIds" : [ 98993 ], "parents" : [ 10275160 ], "children" : [ 10228807, 74016 ] }, { "dbId" : 10280708, "stId" : "R-CFA-2685698", "displayName" : "CaN:CaM:Ca2+ [nucleoplasm]", "schemaClass" : "Complex", "speciesId" : 49646, "parents" : [ 10280716 ], "children" : [ 10280706, 10280696 ] }, { "dbId" : 10280710, "stId" : "R-CFA-2025894", "displayName" : "phospho-NFATC2 [nucleoplasm]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3PTE6", "standardIdentifier" : "uniprot:A0A8I3PTE6", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "NFATC2" ], "parents" : [ 10280714 ], "children" : [ ] }, { "dbId" : 10280704, "stId" : "R-CFA-2685714", "displayName" : "CaN catalytic alpha/beta:Zn++:Fe3+ [nucleoplasm]", "schemaClass" : "Complex", "speciesId" : 49646, "parents" : [ 10280706 ], "children" : [ 200493, 2685584, 10280702 ] }, { "dbId" : 10288897, "stId" : "R-CFA-5607703", "displayName" : "p100:RELB [cytosol]", "schemaClass" : "Complex", "speciesId" : 49646, "diagramIds" : [ 99067 ], "parents" : [ 10288899 ], "children" : [ 10285361, 10288895 ] }, { "dbId" : 10245377, "stId" : "R-CFA-168113", "displayName" : "CHUK:IKBKB:IKBKG [cytosol]", "schemaClass" : "Complex", "speciesId" : 49646, "diagramIds" : [ 99055 ], "parents" : [ ], "children" : [ 10242455, 10238278, 10243285 ] }, { "dbId" : 10280706, "stId" : "R-CFA-2685716", "displayName" : "CaN catalytic alpha/beta:Zn++:Fe3+:CaM:Ca2+ [nucleoplasm]", "schemaClass" : "Complex", "speciesId" : 49646, "parents" : [ 10280708 ], "children" : [ 10280704, 10257198 ] }, { "dbId" : 10289923, "stId" : "R-CFA-5624478", "displayName" : "p21 RAS:GTP:RAF1 [plasma membrane]", "schemaClass" : "Complex", "speciesId" : 49646, "diagramIds" : [ 99122 ], "parents" : [ ], "children" : [ 10239072, 10253655 ] }, { "dbId" : 10288899, "stId" : "R-CFA-5607690", "displayName" : "Active NIK:p-S176,180-IKKA dimer:p100:RELB [cytosol]", "schemaClass" : "Complex", "speciesId" : 49646, "diagramIds" : [ 99068 ], "parents" : [ ], "children" : [ 10288897, 10288891 ] }, { "dbId" : 10245379, "stId" : "R-CFA-202513", "displayName" : "CHUK:p-S177,S181-IKBKB:IKBKG [cytosol]", "schemaClass" : "Complex", "speciesId" : 49646, "diagramIds" : [ 99056 ], "parents" : [ ], "children" : [ 10238290, 10238278, 10243285 ] }, { "dbId" : 10288957, "stId" : "R-CFA-5607696", "displayName" : "p-T231-CARD9:BCL10:MALT1 oligomers [plasma membrane]", "schemaClass" : "Complex", "speciesId" : 49646, "diagramIds" : [ 99026 ], "parents" : [ 10289015, 10289032, 10288961 ], "children" : [ 10288955, 10280654 ] }, { "dbId" : 10288959, "stId" : "R-CFA-5607625", "displayName" : "K63polyUb-TRAF6 oligomer [cytosol]", "schemaClass" : "Polymer", "speciesId" : 49646, "parents" : [ 10288961 ], "children" : [ 10245353 ] }, { "dbId" : 10280767, "stId" : "R-CFA-2685708", "displayName" : "TRAF6 oligomer [cytosol]", "schemaClass" : "Polymer", "speciesId" : 49646, "parents" : [ 10289032 ], "children" : [ 10238140 ] }, { "dbId" : 10292030, "stId" : "R-CFA-5624468", "displayName" : "phospho-RELA [nucleoplasm]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "diagramIds" : [ 99145 ], "identifier" : "A0A8I3P3H3", "standardIdentifier" : "uniprot:A0A8I3P3H3", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "RELA" ], "parents" : [ 10292032 ], "children" : [ ] }, { "dbId" : 10288953, "stId" : "R-CFA-5607622", "displayName" : "p-T231-CARD9 oligomer [plasma membrane]", "schemaClass" : "Polymer", "speciesId" : 49646, "diagramIds" : [ 99016 ], "parents" : [ 10288976, 10288955 ], "children" : [ 10288951 ] }, { "dbId" : 10260794, "stId" : "R-CFA-561191", "displayName" : "PYCARD [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "diagramIds" : [ 99137 ], "identifier" : "A0A8I3RYZ8", "standardIdentifier" : "uniprot:A0A8I3RYZ8", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "PYCARD" ], "parents" : [ 10292020 ], "children" : [ ] }, { "dbId" : 10288955, "stId" : "R-CFA-5607676", "displayName" : "p-T231-CARD9:BCL10 oligomers [plasma membrane]", "schemaClass" : "Complex", "speciesId" : 49646, "diagramIds" : [ 99021 ], "parents" : [ 10288989, 10288957 ], "children" : [ 10288953, 10280652 ] }, { "dbId" : 10292020, "stId" : "R-CFA-5660653", "displayName" : "MALT1 oligomers:active caspase-8:ASC [cytosol]", "schemaClass" : "Complex", "speciesId" : 49646, "diagramIds" : [ 99138 ], "parents" : [ ], "children" : [ 10292018, 10260794 ] }, { "dbId" : 10288951, "stId" : "R-CFA-5607623", "displayName" : "phospho-CARD9 [plasma membrane]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "diagramIds" : [ 99012 ], "identifier" : "A0A8I3N256", "standardIdentifier" : "uniprot:A0A8I3N256", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "CARD9" ], "parents" : [ 10288953 ], "children" : [ ] }, { "dbId" : 10288944, "stId" : "R-CFA-5607643", "displayName" : "MAP3K7 [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3N7L6", "standardIdentifier" : "uniprot:A0A8I3N7L6", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "MAP3K7" ], "parents" : [ 10288946 ], "children" : [ ] }, { "dbId" : 10275120, "stId" : "R-CFA-2025977", "displayName" : "Calcineurin (CaN) [cytosol]", "schemaClass" : "Complex", "speciesId" : 49646, "diagramIds" : [ 98995 ], "parents" : [ ], "children" : [ 10235153, 10275118 ] }, { "dbId" : 10285361, "stId" : "R-CFA-2677931", "displayName" : "NFKB2 [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3PK60", "standardIdentifier" : "uniprot:A0A8I3PK60", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "NFKB2" ], "parents" : [ 10288897 ], "children" : [ ] }, { "dbId" : 10288946, "stId" : "R-CFA-5607691", "displayName" : "TAB1:TAB2/TAB3:K63polyUb-34,158-TAK1 [cytosol]", "schemaClass" : "Complex", "speciesId" : 49646, "parents" : [ 10288963 ], "children" : [ 10288944, 10257943, 10257951 ] }, { "dbId" : 10292018, "stId" : "R-CFA-5660654", "displayName" : "MALT1:active caspase-8 [cytosol]", "schemaClass" : "Complex", "speciesId" : 49646, "diagramIds" : [ 99135 ], "parents" : [ 10292020 ], "children" : [ 10245344, 10235135 ] }, { "dbId" : 10275116, "stId" : "R-CFA-2025955", "displayName" : "PPP3CA,B [cytosol]", "schemaClass" : "DefinedSet", "speciesId" : 49646, "parents" : [ 10275118 ], "children" : [ 10275110, 10275114 ] }, { "dbId" : 10257196, "stId" : "R-CFA-9016871", "displayName" : "CALM1 [nucleoplasm]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3PNY6", "standardIdentifier" : "uniprot:A0A8I3PNY6", "referenceType" : "ReferenceGeneProduct", "parents" : [ 10257198 ], "children" : [ ] }, { "dbId" : 10275118, "stId" : "R-CFA-2025949", "displayName" : "PPP3CA,B:Fe3+:Zn2+ [cytosol]", "schemaClass" : "Complex", "speciesId" : 49646, "parents" : [ 10275160, 10275120 ], "children" : [ 111736, 29426, 10275116 ] }, { "dbId" : 10257198, "stId" : "R-CFA-629658", "displayName" : "CALM1:4xCa2+ [nucleoplasm]", "schemaClass" : "Complex", "speciesId" : 49646, "parents" : [ 10280706 ], "children" : [ 29496, 10257196 ] }, { "dbId" : 10288938, "stId" : "R-CFA-5607699", "displayName" : "p52:RELB [cytosol]", "schemaClass" : "Complex", "speciesId" : 49646, "diagramIds" : [ 99083 ], "parents" : [ ], "children" : [ 10238250, 10288895 ] }, { "dbId" : 10238250, "stId" : "R-CFA-168144", "displayName" : "NFKB2 [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3PK60", "standardIdentifier" : "uniprot:A0A8I3PK60", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "NFKB2" ], "parents" : [ 10288938 ], "children" : [ ] }, { "dbId" : 10275114, "stId" : "R-CFA-201771", "displayName" : "PPP3CA [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3PS73", "standardIdentifier" : "uniprot:A0A8I3PS73", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "PPP3CA" ], "parents" : [ 10275116 ], "children" : [ ] }, { "dbId" : 10245412, "stId" : "R-CFA-202562", "displayName" : "CHUK:p-S177,S181-IKBKB:pUb-IKBKG [cytosol]", "schemaClass" : "Complex", "speciesId" : 49646, "diagramIds" : [ 99090 ], "parents" : [ ], "children" : [ 10245410, 10238290, 10243285 ] }, { "dbId" : 113592, "stId" : "R-ALL-113592", "displayName" : "ATP [cytosol]", "schemaClass" : "SimpleEntity", "speciesId" : 0, "diagramIds" : [ 98979, 99043, 99106, 99010, 99110, 99050, 99054, 99061, 99124, 99129, 99033, 99098, 99070 ], "identifier" : "30616", "standardIdentifier" : "chebi:30616", "referenceType" : "ReferenceMolecule", "parents" : [ ], "children" : [ ] }, { "dbId" : 10275110, "stId" : "R-CFA-2025869", "displayName" : "PPP3CB [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3MW99", "standardIdentifier" : "uniprot:A0A8I3MW99", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "PPP3CB" ], "parents" : [ 10275116 ], "children" : [ ] }, { "dbId" : 10288928, "stId" : "R-CFA-5607636", "displayName" : "phospho-NFKB2 [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3PK60", "standardIdentifier" : "uniprot:A0A8I3PK60", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "NFKB2" ], "parents" : [ 10288930 ], "children" : [ ] }, { "dbId" : 10288930, "stId" : "R-CFA-5607694", "displayName" : "K48-polyUb-p-7S-p100:RELB [cytosol]", "schemaClass" : "Complex", "speciesId" : 49646, "diagramIds" : [ 99080 ], "parents" : [ ], "children" : [ 10288928, 10288895 ] }, { "dbId" : 10245410, "stId" : "R-CFA-202530", "displayName" : "IKBKG [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3S792", "standardIdentifier" : "uniprot:A0A8I3S792", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "IKBKG" ], "parents" : [ 10245412 ], "children" : [ ] }, { "dbId" : 10288989, "stId" : "R-CFA-5607682", "displayName" : "p-T231-CARD9:BCL10 oligomers:MALT1 [plasma membrane]", "schemaClass" : "Complex", "speciesId" : 49646, "diagramIds" : [ 99024 ], "parents" : [ ], "children" : [ 10245344, 10288955 ] }, { "dbId" : 10261336, "stId" : "R-CFA-939250", "displayName" : "Ub-48-UBA52(1-76) [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3PFZ3", "standardIdentifier" : "uniprot:A0A8I3PFZ3", "referenceType" : "ReferenceGeneProduct", "parents" : [ 10261374 ], "children" : [ ] }, { "dbId" : 10288984, "stId" : "R-CFA-5607640", "displayName" : "phospho-PLCG2 [plasma membrane]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "diagramIds" : [ 98986 ], "identifier" : "A0A8I3NZG2", "standardIdentifier" : "uniprot:A0A8I3NZG2", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "PLCG2" ], "parents" : [ ], "children" : [ ] }, { "dbId" : 10275160, "stId" : "R-CFA-2026003", "displayName" : "PPP3CA,B:Calmodulin [cytosol]", "schemaClass" : "Complex", "speciesId" : 49646, "parents" : [ 10275162 ], "children" : [ 10234116, 10275118 ] }, { "dbId" : 5621136, "stId" : "R-ALL-5621136", "displayName" : "alpha-mannan [plasma membrane]", "schemaClass" : "SimpleEntity", "speciesId" : 0, "diagramIds" : [ 99163 ], "identifier" : "28808", "standardIdentifier" : "chebi:28808", "referenceType" : "ReferenceMolecule", "parents" : [ 9038391 ], "children" : [ ] }, { "dbId" : 10286426, "stId" : "R-CFA-5218734", "displayName" : "phospho-PRKCD [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "diagramIds" : [ 99005 ], "identifier" : "A0A8I3PZJ7", "standardIdentifier" : "uniprot:A0A8I3PZJ7", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "PRKCD" ], "parents" : [ 10288980 ], "children" : [ ] }, { "dbId" : 10275162, "stId" : "R-CFA-2025947", "displayName" : "Calcineurin:Calmodulin (CaN:CaM) [cytosol]", "schemaClass" : "Complex", "speciesId" : 49646, "diagramIds" : [ 98996 ], "parents" : [ 10280620 ], "children" : [ 10275158, 10275160 ] }, { "dbId" : 10261339, "stId" : "R-CFA-939249", "displayName" : "RPS27A [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3NFB9", "standardIdentifier" : "uniprot:A0A8I3NFB9", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "RPS27A" ], "parents" : [ 10261374 ], "children" : [ ] }, { "dbId" : 5621138, "stId" : "R-ALL-5621138", "displayName" : "TDM [plasma membrane]", "schemaClass" : "SimpleEntity", "speciesId" : 0, "diagramIds" : [ 99117 ], "identifier" : "82624", "standardIdentifier" : "chebi:82624", "referenceType" : "ReferenceMolecule", "parents" : [ 10289657, 9038391 ], "children" : [ ] }, { "dbId" : 10288980, "stId" : "R-CFA-5607700", "displayName" : "DAGs:p-T507,S645,S664-PRKCD [plasma membrane]", "schemaClass" : "Complex", "speciesId" : 49646, "diagramIds" : [ 99006 ], "parents" : [ ], "children" : [ 10286426, 112275 ] }, { "dbId" : 10275156, "stId" : "R-CFA-2025924", "displayName" : "p-NFATC1,2,3 [cytosol]", "schemaClass" : "DefinedSet", "speciesId" : 49646, "diagramIds" : [ 98999 ], "parents" : [ ], "children" : [ 10275154, 10275136 ] }, { "dbId" : 10261333, "stId" : "R-CFA-939202", "displayName" : "Ub-48-RPS27A(1-76) [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3NUE4", "standardIdentifier" : "uniprot:A0A8I3NUE4", "referenceType" : "ReferenceGeneProduct", "parents" : [ 10261374 ], "children" : [ ] }, { "dbId" : 10275158, "stId" : "R-CFA-2025950", "displayName" : "Calcineurin alpha regulatory subunit:Calcium [cytosol]", "schemaClass" : "Complex", "speciesId" : 49646, "parents" : [ 10275162 ], "children" : [ 10235153, 74016 ] }, { "dbId" : 10253655, "stId" : "R-CFA-167205", "displayName" : "RAF1 [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "diagramIds" : [ 99121 ], "identifier" : "A0A8I3PZA0", "standardIdentifier" : "uniprot:A0A8I3PZA0", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "RAF1" ], "parents" : [ 10289923 ], "children" : [ ] }, { "dbId" : 10288976, "stId" : "R-CFA-5607678", "displayName" : "p-T231-CARD9 oligomer:BCL10 [plasma membrane]", "schemaClass" : "Complex", "speciesId" : 49646, "diagramIds" : [ 99019 ], "parents" : [ ], "children" : [ 10245360, 10288953 ] }, { "dbId" : 10275154, "stId" : "R-CFA-2025848", "displayName" : "phospho-NFATC2 [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3PTE6", "standardIdentifier" : "uniprot:A0A8I3PTE6", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "NFATC2" ], "parents" : [ 10275156 ], "children" : [ ] }, { "dbId" : 10238290, "stId" : "R-CFA-202506", "displayName" : "phospho-IKBKB [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3N4F2", "standardIdentifier" : "uniprot:A0A8I3N4F2", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "IKBKB" ], "parents" : [ 10245412, 10245379 ], "children" : [ ] }, { "dbId" : 10238284, "stId" : "R-CFA-177667", "displayName" : "phospho-CHUK [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3P499", "standardIdentifier" : "uniprot:A0A8I3P499", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "CHUK" ], "parents" : [ 10288889 ], "children" : [ ] }, { "dbId" : 10288969, "stId" : "R-CFA-5607683", "displayName" : "TAB1:TAB2,TAB3:K63polyUb-34,158-p-T178,184,187,S192-TAK1 [cytosol]", "schemaClass" : "Complex", "speciesId" : 49646, "parents" : [ 10288971 ], "children" : [ 10288967, 10257943, 10257951 ] }, { "dbId" : 10288971, "stId" : "R-CFA-5607673", "displayName" : "p-T231-CARD9:BCL10:MALT1:K63polyUb-TRAF6 oligomers:TAB1:TAB2/TAB3:K63polyUb-34,158-p3Y,1S-TAK1 [plasma membrane]", "schemaClass" : "Complex", "speciesId" : 49646, "diagramIds" : [ 99052 ], "parents" : [ ], "children" : [ 10288961, 10288969 ] }, { "dbId" : 10238278, "stId" : "R-CFA-168108", "displayName" : "IKBKG [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3S792", "standardIdentifier" : "uniprot:A0A8I3S792", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "IKBKG" ], "parents" : [ 10245379, 10245377 ], "children" : [ ] }, { "dbId" : 10264902, "stId" : "R-CFA-1861712", "displayName" : "phospho-SYK [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3P3G0", "standardIdentifier" : "uniprot:A0A8I3P3G0", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "SYK" ], "parents" : [ 10289645 ], "children" : [ ] }, { "dbId" : 10288967, "stId" : "R-CFA-5607649", "displayName" : "phospho-MAP3K7 [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3N7L6", "standardIdentifier" : "uniprot:A0A8I3N7L6", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "MAP3K7" ], "parents" : [ 10288969 ], "children" : [ ] }, { "dbId" : 10275136, "stId" : "R-CFA-2025953", "displayName" : "phospho-NFATC1 [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3MEU0", "standardIdentifier" : "uniprot:A0A8I3MEU0", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "NFATC1" ], "parents" : [ 10275156 ], "children" : [ ] }, { "dbId" : 10288961, "stId" : "R-CFA-5607675", "displayName" : "p-T231-CARD9:BCL10:MALT1:K63polyUb-TRAF6 oligomers [plasma membrane]", "schemaClass" : "Complex", "speciesId" : 49646, "diagramIds" : [ 99038 ], "parents" : [ 10289047, 10288963, 10288971 ], "children" : [ 10288959, 10288957 ] }, { "dbId" : 10253633, "stId" : "R-CFA-168189", "displayName" : "MAP3K14 [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "diagramIds" : [ 99059, 99063 ], "identifier" : "A0A8I3MWN3", "standardIdentifier" : "uniprot:A0A8I3MWN3", "referenceType" : "ReferenceGeneProduct", "parents" : [ 10288891 ], "children" : [ ] }, { "dbId" : 10292032, "stId" : "R-CFA-5660974", "displayName" : "p-S276-RELA:RELB [nucleoplasm]", "schemaClass" : "Complex", "speciesId" : 49646, "diagramIds" : [ 99146 ], "parents" : [ ], "children" : [ 10289002, 10292030 ] }, { "dbId" : 10288963, "stId" : "R-CFA-5607695", "displayName" : "p-T231-CARD9:BCL10:MALT1:K63polyUb-TRAF6 oligomers:TAB1:TAB2/TAB3:K63polyUb-34,158-TAK1 [plasma membrane]", "schemaClass" : "Complex", "speciesId" : 49646, "diagramIds" : [ 99046 ], "parents" : [ ], "children" : [ 10288946, 10288961 ] }, { "dbId" : 10289021, "stId" : "R-CFA-2130683", "displayName" : "CLEC7A [plasma membrane]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3QCX4", "standardIdentifier" : "uniprot:A0A8I3QCX4", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "CLEC7A" ], "parents" : [ 10289023 ], "children" : [ ] }, { "dbId" : 10261374, "stId" : "R-CFA-912722", "displayName" : "K48-Ub [cytosol]", "schemaClass" : "DefinedSet", "speciesId" : 49646, "diagramIds" : [ 99079 ], "parents" : [ ], "children" : [ 10261333, 10261348, 10261339, 10261336 ] }, { "dbId" : 10289023, "stId" : "R-CFA-5607680", "displayName" : "CLEC7A:1,3-beta-D-glucan [plasma membrane]", "schemaClass" : "Complex", "speciesId" : 49646, "diagramIds" : [ 98980 ], "parents" : [ ], "children" : [ 2186970, 10289021 ] }, { "dbId" : 10289015, "stId" : "R-CFA-5607701", "displayName" : "p-T231-CARD9:BCL10:MALT1 oligomers:TRAF6 [plasma membrane]", "schemaClass" : "Complex", "speciesId" : 49646, "diagramIds" : [ 99029 ], "parents" : [ ], "children" : [ 10288957, 10238140 ] }, { "dbId" : 10289004, "stId" : "R-CFA-5607679", "displayName" : "p52:RELB [nucleoplasm]", "schemaClass" : "Complex", "speciesId" : 49646, "diagramIds" : [ 99086 ], "parents" : [ ], "children" : [ 10238339, 10289002 ] }, { "dbId" : 10289002, "stId" : "R-CFA-5607656", "displayName" : "RELB [nucleoplasm]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "diagramIds" : [ 99144 ], "identifier" : "A0A8I3MRI7", "standardIdentifier" : "uniprot:A0A8I3MRI7", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "RELB" ], "parents" : [ 10289004, 10292032 ], "children" : [ ] }, { "dbId" : 10261348, "stId" : "R-CFA-939219", "displayName" : "UBA52 [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "P63050", "standardIdentifier" : "uniprot:P63050", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "UBA52" ], "parents" : [ 10261374 ], "children" : [ ] }, { "dbId" : 10288997, "stId" : "R-CFA-5607689", "displayName" : "DAGs:active p-T507,S645,S664-PRKCD [plasma membrane]", "schemaClass" : "Complex", "speciesId" : 49646, "diagramIds" : [ 99008 ], "parents" : [ ], "children" : [ 10243236, 112275 ] }, { "dbId" : 10288995, "stId" : "R-CFA-5607662", "displayName" : "CARD9 [plasma membrane]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "diagramIds" : [ 99011 ], "identifier" : "A0A8I3N256", "standardIdentifier" : "uniprot:A0A8I3N256", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "CARD9" ], "parents" : [ ], "children" : [ ] } ], "edges" : [ { "dbId" : 10289052, "stId" : "R-CFA-5607759", "displayName" : "TRIKA2 binds K63polyUb-TRAF6 oligomer", "schemaClass" : "Reaction", "speciesId" : 0, "preceding" : [ 10289045 ], "following" : [ 10289050 ], "inputs" : [ 10288961, 10257953 ], "outputs" : [ 10289047 ], "efs" : [ ], "diagramIds" : [ 99039 ], "entityFunctionalStatus" : [ ] }, { "dbId" : 10288925, "stId" : "R-CFA-5607723", "displayName" : "SCF-beta-TRCP binds p-7S-p100 in active NIK:p-S176,180-IKKA dimer:p-7S-p100:RELB", "schemaClass" : "Reaction", "speciesId" : 0, "inputs" : [ 10288921, 10265580 ], "outputs" : [ 10288923 ], "efs" : [ ], "diagramIds" : [ 99073 ], "entityFunctionalStatus" : [ ] }, { "dbId" : 10288991, "stId" : "R-CFA-5607736", "displayName" : "MALT1 oligomerizes", "schemaClass" : "Polymerisation", "speciesId" : 0, "preceding" : [ 10289011 ], "following" : [ 10289017 ], "inputs" : [ 10245344, 10288989 ], "outputs" : [ 10288957 ], "efs" : [ ], "diagramIds" : [ 99025 ], "entityFunctionalStatus" : [ ] }, { "dbId" : 10289050, "stId" : "R-CFA-5607757", "displayName" : "K63polyUb-TRAF6 ubiquitinates TAK1", "schemaClass" : "BlackBoxEvent", "speciesId" : 0, "preceding" : [ 10289052 ], "following" : [ 10288974 ], "inputs" : [ 10289047, 10238454, 113592, 10238488 ], "outputs" : [ 111294, 10288963, 10238488, 76577 ], "catalysts" : [ 10289047 ], "efs" : [ ], "diagramIds" : [ 99042 ], "entityFunctionalStatus" : [ ] }, { "dbId" : 10280730, "stId" : "R-CFA-2730872", "displayName" : "Activation of Calcineurin", "schemaClass" : "Reaction", "speciesId" : 0, "following" : [ 10280623 ], "inputs" : [ 10275120, 10234116, 74016 ], "outputs" : [ 10275162 ], "efs" : [ ], "diagramIds" : [ 98992 ], "entityFunctionalStatus" : [ ] }, { "dbId" : 10288987, "stId" : "R-CFA-5607735", "displayName" : "p-Y753,Y759-PLCG2 hydrolyses PIP2", "schemaClass" : "Reaction", "speciesId" : 0, "preceding" : [ 10289042 ], "following" : [ 10288982 ], "inputs" : [ 29356, 179856 ], "outputs" : [ 114520, 112275 ], "catalysts" : [ 10288984 ], "efs" : [ ], "diagramIds" : [ 98987 ], "entityFunctionalStatus" : [ ] }, { "dbId" : 10289045, "stId" : "R-CFA-5607756", "displayName" : "TRAF6 oligomer autoubiquitinates", "schemaClass" : "BlackBoxEvent", "speciesId" : 0, "preceding" : [ 10289034 ], "following" : [ 10289052 ], "inputs" : [ 10238454, 113592, 10238488, 10289032 ], "outputs" : [ 111294, 10288961, 10238488, 76577 ], "catalysts" : [ 10289032 ], "efs" : [ ], "diagramIds" : [ 99032 ], "entityFunctionalStatus" : [ ] }, { "dbId" : 10288982, "stId" : "R-CFA-5607734", "displayName" : "PKC-delta translocates to plasma membrane", "schemaClass" : "Reaction", "speciesId" : 0, "preceding" : [ 10288987 ], "following" : [ 10289013 ], "inputs" : [ 10286426, 112275 ], "outputs" : [ 10288980 ], "efs" : [ ], "diagramIds" : [ 99004 ], "entityFunctionalStatus" : [ ] }, { "dbId" : 10289042, "stId" : "R-CFA-5607755", "displayName" : "p-Y753,Y759-PLCG2 translocates from cytosol to plasma membrane", "schemaClass" : "Reaction", "speciesId" : 0, "following" : [ 10288987 ], "inputs" : [ 10289040 ], "outputs" : [ 10288984 ], "efs" : [ ], "diagramIds" : [ 98984 ], "entityFunctionalStatus" : [ ] }, { "dbId" : 10288978, "stId" : "R-CFA-5607733", "displayName" : "BCL10 binds CARD9", "schemaClass" : "Reaction", "speciesId" : 0, "preceding" : [ 10289038 ], "following" : [ 10288993 ], "inputs" : [ 10245360, 10288953 ], "outputs" : [ 10288976 ], "efs" : [ ], "diagramIds" : [ 99017 ], "entityFunctionalStatus" : [ ] }, { "dbId" : 10289682, "stId" : "R-CFA-5621370", "displayName" : "SYK autophosphorylates", "schemaClass" : "Reaction", "speciesId" : 0, "preceding" : [ 10289679 ], "inputs" : [ 113592, 10289677 ], "outputs" : [ 29370, 10289645 ], "catalysts" : [ 10289677 ], "efs" : [ ], "diagramIds" : [ 99105 ], "entityFunctionalStatus" : [ ] }, { "dbId" : 10288908, "stId" : "R-CFA-5607722", "displayName" : "Active NIK phosphorylates IKKA dimer", "schemaClass" : "Reaction", "speciesId" : 0, "inputs" : [ 10253633, 113592, 10288905 ], "outputs" : [ 29370, 10288891 ], "catalysts" : [ 10253633 ], "efs" : [ ], "diagramIds" : [ 99060 ], "entityFunctionalStatus" : [ ] }, { "dbId" : 10280718, "stId" : "R-CFA-2730867", "displayName" : "Translocation of CaN:CaM:NFAT to nucleus", "schemaClass" : "Reaction", "speciesId" : 0, "preceding" : [ 10280623 ], "inputs" : [ 10280620 ], "outputs" : [ 10280716 ], "efs" : [ ], "diagramIds" : [ 99002 ], "entityFunctionalStatus" : [ ] }, { "dbId" : 10289038, "stId" : "R-CFA-5607753", "displayName" : "CARD9 oligomerizes", "schemaClass" : "Polymerisation", "speciesId" : 0, "preceding" : [ 10289000 ], "following" : [ 10288978 ], "inputs" : [ 10288951, 10289036 ], "outputs" : [ 10288953 ], "efs" : [ ], "diagramIds" : [ 99014 ], "entityFunctionalStatus" : [ ] }, { "dbId" : 10288974, "stId" : "R-CFA-5607732", "displayName" : "K63polyUb-TAK1 autophosphorylates", "schemaClass" : "Reaction", "speciesId" : 0, "preceding" : [ 10289050 ], "following" : [ 10289009 ], "inputs" : [ 10288963, 113592 ], "outputs" : [ 29370, 10288971 ], "catalysts" : [ 10288963 ], "efs" : [ ], "diagramIds" : [ 99049 ], "entityFunctionalStatus" : [ ] }, { "dbId" : 10289679, "stId" : "R-CFA-5621366", "displayName" : "SYK binds to p-Y65,Y76-FCER1G", "schemaClass" : "Reaction", "speciesId" : 0, "preceding" : [ 10289670 ], "following" : [ 10289682 ], "inputs" : [ 10289643, 10235016 ], "outputs" : [ 10289677 ], "efs" : [ ], "diagramIds" : [ 99102 ], "entityFunctionalStatus" : [ ] }, { "dbId" : 10289928, "stId" : "R-CFA-5624494", "displayName" : "RAF1 binds p21 RAS:GTP", "schemaClass" : "Reaction", "speciesId" : 0, "following" : [ 10289926 ], "inputs" : [ 10239072, 10253655 ], "outputs" : [ 10289923 ], "efs" : [ ], "diagramIds" : [ 99119 ], "entityFunctionalStatus" : [ ] }, { "dbId" : 10289034, "stId" : "R-CFA-5607751", "displayName" : "TRAF6 oligomerizes", "schemaClass" : "Polymerisation", "speciesId" : 0, "preceding" : [ 10289017 ], "following" : [ 10289045 ], "inputs" : [ 10289015, 10238140 ], "outputs" : [ 10289032 ], "efs" : [ ], "diagramIds" : [ 99030 ], "entityFunctionalStatus" : [ ] }, { "dbId" : 10289675, "stId" : "R-CFA-5621363", "displayName" : "SYK phosphorylates PLCG2 in p-6Y-SYK:p-Y65,Y76-FCER1G:PLCG2", "schemaClass" : "Reaction", "speciesId" : 0, "following" : [ 10289649 ], "inputs" : [ 113592, 10289672 ], "outputs" : [ 29370, 10289647 ], "catalysts" : [ 10289672 ], "efs" : [ ], "diagramIds" : [ 99109 ], "entityFunctionalStatus" : [ ] }, { "dbId" : 10288901, "stId" : "R-CFA-5607720", "displayName" : "p100:RELB binds active NIK:p-IKKA dimer", "schemaClass" : "Reaction", "speciesId" : 0, "inputs" : [ 10288897, 10288891 ], "outputs" : [ 10288899 ], "efs" : [ ], "diagramIds" : [ 99066 ], "entityFunctionalStatus" : [ ] }, { "dbId" : 10289030, "stId" : "R-CFA-5607750", "displayName" : "SRC kinase phosphorylates CLEC7A:1,3-beta-D-glucan", "schemaClass" : "Reaction", "speciesId" : 0, "inputs" : [ 113592, 10289023 ], "outputs" : [ 29370, 10289028 ], "catalysts" : [ 10240722 ], "efs" : [ ], "diagramIds" : [ 98978 ], "entityFunctionalStatus" : [ ] }, { "dbId" : 10288903, "stId" : "R-CFA-5607721", "displayName" : "Activation of NIK", "schemaClass" : "Reaction", "speciesId" : 0, "inputs" : [ 10253633 ], "outputs" : [ 10253633 ], "efs" : [ ], "diagramIds" : [ 99058 ], "entityFunctionalStatus" : [ ] }, { "dbId" : 10289670, "stId" : "R-CFA-5621355", "displayName" : "LYN and FYN phosphorylate FCER1G in CLEC6A:FCERG and CLEC4E:FCERG", "schemaClass" : "Reaction", "speciesId" : 0, "preceding" : [ 10289665 ], "following" : [ 10289679 ], "inputs" : [ 113592, 10289663 ], "outputs" : [ 29370, 10289643 ], "catalysts" : [ 10289667 ], "efs" : [ ], "diagramIds" : [ 99096 ], "entityFunctionalStatus" : [ ] }, { "dbId" : 10289926, "stId" : "R-CFA-5624492", "displayName" : "PAK phosphorylates p21 RAF1 on S338", "schemaClass" : "Reaction", "speciesId" : 0, "preceding" : [ 10289928 ], "following" : [ 10289921 ], "inputs" : [ 10289923, 113592 ], "outputs" : [ 29370, 10289913 ], "catalysts" : [ 10253034 ], "efs" : [ ], "diagramIds" : [ 99123 ], "entityFunctionalStatus" : [ ] }, { "dbId" : 10289665, "stId" : "R-CFA-5621354", "displayName" : "CLEC4E binds alpha-mannan and trehalose-6-6'-dimycolate", "schemaClass" : "Reaction", "speciesId" : 0, "following" : [ 10289670 ], "inputs" : [ 9038391, 10289661 ], "outputs" : [ 10289663 ], "efs" : [ ], "diagramIds" : [ 99092 ], "entityFunctionalStatus" : [ ] }, { "dbId" : 10289921, "stId" : "R-CFA-5624486", "displayName" : "SFKs phosphorylates RAF1 on Y340,Y341", "schemaClass" : "BlackBoxEvent", "speciesId" : 0, "preceding" : [ 10289926 ], "inputs" : [ 113592, 10289913 ], "outputs" : [ 29370, 10289919 ], "catalysts" : [ 10289667 ], "efs" : [ ], "diagramIds" : [ 99128 ], "entityFunctionalStatus" : [ ] }, { "dbId" : 10292034, "stId" : "R-CFA-5660980", "displayName" : "p-S276-RELA binds RELB", "schemaClass" : "Reaction", "speciesId" : 0, "inputs" : [ 10289002, 10292030 ], "outputs" : [ 10292032 ], "efs" : [ ], "diagramIds" : [ 99143 ], "entityFunctionalStatus" : [ ] }, { "dbId" : 10292025, "stId" : "R-CFA-5660663", "displayName" : "Caspase-8 cleaves IL1B precursor", "schemaClass" : "Reaction", "speciesId" : 0, "preceding" : [ 10292022 ], "inputs" : [ 10258184 ], "outputs" : [ 10258194, 10258202 ], "catalysts" : [ 10292020 ], "efs" : [ ], "diagramIds" : [ 99139 ], "entityFunctionalStatus" : [ ] }, { "dbId" : 10289017, "stId" : "R-CFA-5607747", "displayName" : "TRAF6 binds MALT1 oligomers", "schemaClass" : "Reaction", "speciesId" : 0, "preceding" : [ 10288991 ], "following" : [ 10289034 ], "inputs" : [ 10288957, 10238140 ], "outputs" : [ 10289015 ], "efs" : [ ], "diagramIds" : [ 99027 ], "entityFunctionalStatus" : [ ] }, { "dbId" : 10292027, "stId" : "R-CFA-5660665", "displayName" : "Caspase-8 binds MALT", "schemaClass" : "Reaction", "speciesId" : 0, "following" : [ 10292022 ], "inputs" : [ 10245344, 10235135 ], "outputs" : [ 10292018 ], "efs" : [ ], "diagramIds" : [ 99133 ], "entityFunctionalStatus" : [ ] }, { "dbId" : 10289659, "stId" : "R-CFA-5621353", "displayName" : "CLEC4D binds mycobacterial trehalose-6,6'-dimycolate (TDM)", "schemaClass" : "Reaction", "speciesId" : 0, "inputs" : [ 10289655, 5621138 ], "outputs" : [ 10289657 ], "efs" : [ ], "diagramIds" : [ 99115 ], "entityFunctionalStatus" : [ ] }, { "dbId" : 10289013, "stId" : "R-CFA-5607746", "displayName" : "PKC-delta is activated", "schemaClass" : "Reaction", "speciesId" : 0, "preceding" : [ 10288982 ], "following" : [ 10289000 ], "inputs" : [ 10288980 ], "outputs" : [ 10288997 ], "efs" : [ ], "diagramIds" : [ 99007 ], "entityFunctionalStatus" : [ ] }, { "dbId" : 10292022, "stId" : "R-CFA-5660662", "displayName" : "ASC binds Caspase-8 complex", "schemaClass" : "Reaction", "speciesId" : 0, "preceding" : [ 10292027 ], "following" : [ 10292025 ], "inputs" : [ 10292018, 10260794 ], "outputs" : [ 10292020 ], "efs" : [ ], "diagramIds" : [ 99136 ], "entityFunctionalStatus" : [ ] }, { "dbId" : 10289649, "stId" : "R-CFA-5621347", "displayName" : "PLCG2 translocates from cytosol to plasma membrane", "schemaClass" : "Reaction", "speciesId" : 0, "preceding" : [ 10289675 ], "inputs" : [ 10289647 ], "outputs" : [ 10288984, 10289645 ], "efs" : [ ], "diagramIds" : [ 99114 ], "entityFunctionalStatus" : [ ] }, { "dbId" : 10289009, "stId" : "R-CFA-5607742", "displayName" : "K63polyUb-p-3T,1S-TAK1 phosphorylates IKK-beta", "schemaClass" : "Reaction", "speciesId" : 0, "preceding" : [ 10288974 ], "following" : [ 10245415 ], "inputs" : [ 10245377, 113592 ], "outputs" : [ 10245379, 29370 ], "catalysts" : [ 10288971 ], "efs" : [ ], "diagramIds" : [ 99053 ], "entityFunctionalStatus" : [ ] }, { "dbId" : 10289011, "stId" : "R-CFA-5607744", "displayName" : "MALT1 binds BCL10", "schemaClass" : "Reaction", "speciesId" : 0, "preceding" : [ 10288993 ], "following" : [ 10288991 ], "inputs" : [ 10245344, 10288955 ], "outputs" : [ 10288989 ], "efs" : [ ], "diagramIds" : [ 99022 ], "entityFunctionalStatus" : [ ] }, { "dbId" : 10288940, "stId" : "R-CFA-5607731", "displayName" : "26S proteasome processes p-7S-p100:RELB to form p52:RELB", "schemaClass" : "BlackBoxEvent", "speciesId" : 0, "inputs" : [ 10288930 ], "outputs" : [ 10226816, 10288938 ], "catalysts" : [ 10226918 ], "efs" : [ ], "diagramIds" : [ 99081 ], "entityFunctionalStatus" : [ ] }, { "dbId" : 10289006, "stId" : "R-CFA-5607741", "displayName" : "p52:RELB translocates from cytosol to nucleus", "schemaClass" : "Reaction", "speciesId" : 0, "inputs" : [ 10288938 ], "outputs" : [ 10289004 ], "efs" : [ ], "diagramIds" : [ 99085 ], "entityFunctionalStatus" : [ ] }, { "dbId" : 10280623, "stId" : "R-CFA-2730849", "displayName" : "Calcineurin binds and dephosphorylates NFAT", "schemaClass" : "BlackBoxEvent", "speciesId" : 0, "preceding" : [ 10280730 ], "following" : [ 10280718 ], "inputs" : [ 29356, 10275156, 10275162 ], "outputs" : [ 29372, 10280620 ], "catalysts" : [ 10275162 ], "efs" : [ ], "diagramIds" : [ 98997 ], "entityFunctionalStatus" : [ ] }, { "dbId" : 10288936, "stId" : "R-CFA-5607726", "displayName" : "Active NIK:p-S176,180-IKKA dimer phosphorylates p100:RELB", "schemaClass" : "Reaction", "speciesId" : 0, "inputs" : [ 10288899, 113592 ], "outputs" : [ 29370, 10288921 ], "catalysts" : [ 10288899 ], "efs" : [ ], "diagramIds" : [ 99069 ], "entityFunctionalStatus" : [ ] }, { "dbId" : 10289000, "stId" : "R-CFA-5607740", "displayName" : "PKC-delta phosphorylates CARD9", "schemaClass" : "Reaction", "speciesId" : 0, "preceding" : [ 10289013 ], "following" : [ 10289038 ], "inputs" : [ 10288995, 113592 ], "outputs" : [ 10288951, 29370 ], "catalysts" : [ 10288997 ], "efs" : [ ], "diagramIds" : [ 99009 ], "entityFunctionalStatus" : [ ] }, { "dbId" : 10288933, "stId" : "R-CFA-5607725", "displayName" : "SCF-beta-TRCP ubiquitinates p-7S-p100:RELB in active NIK:p-176,S180-IKKA dimer:p-7S-p100:SCF-beta-TRCP", "schemaClass" : "BlackBoxEvent", "speciesId" : 0, "inputs" : [ 10288923, 10264297, 10284783, 10261374 ], "outputs" : [ 10288930, 10288891, 10264297, 10284783, 10265580 ], "catalysts" : [ 10288923 ], "efs" : [ ], "diagramIds" : [ 99076 ], "entityFunctionalStatus" : [ ] }, { "dbId" : 10245415, "stId" : "R-CFA-202534", "displayName" : "Ubiquitination of NEMO by TRAF6", "schemaClass" : "BlackBoxEvent", "speciesId" : 0, "preceding" : [ 10289009 ], "inputs" : [ 10245379, 10238454, 10238488 ], "outputs" : [ 10245412, 10238488 ], "catalysts" : [ 10245355 ], "efs" : [ ], "diagramIds" : [ 99087 ], "entityFunctionalStatus" : [ ] }, { "dbId" : 10288993, "stId" : "R-CFA-5607737", "displayName" : "BCL10 oligomerizes", "schemaClass" : "Polymerisation", "speciesId" : 0, "preceding" : [ 10288978 ], "following" : [ 10289011 ], "inputs" : [ 10245360, 10288976 ], "outputs" : [ 10288955 ], "efs" : [ ], "diagramIds" : [ 99020 ], "entityFunctionalStatus" : [ ] } ], "subpathways" : [ { "dbId" : 10331275, "stId" : "R-CFA-5660668", "displayName" : "CLEC7A/inflammasome pathway", "events" : [ 10292025, 10292027, 10292022 ] }, { "dbId" : 10331197, "stId" : "R-CFA-5621480", "displayName" : "Dectin-2 family", "events" : [ 10289679, 10289659, 10289675, 10289670, 10289665, 10289649, 10289682 ] }, { "dbId" : 10329869, "stId" : "R-CFA-5607764", "displayName" : "CLEC7A (Dectin-1) signaling", "events" : [ 10289052, 10288908, 10288940, 10288925, 10289006, 10288936, 10288901, 10288933, 10288903, 10288991, 10289017, 10289050, 10288987, 10289013, 10289045, 10288982, 10280718, 10280623, 10280730, 10289009, 10289042, 10288978, 10289011, 10289038, 10288974, 10289000, 10289034, 10292025, 10292027, 10292022, 10289030, 10245415, 10288993 ] }, { "dbId" : 10330993, "stId" : "R-CFA-5607763", "displayName" : "CLEC7A (Dectin-1) induces NFAT activation", "events" : [ 10280718, 10280623, 10280730 ] }, { "dbId" : 10331201, "stId" : "R-CFA-5621575", "displayName" : "CD209 (DC-SIGN) signaling", "events" : [ 10289928, 10289926, 10289921, 10292034 ] }, { "dbId" : 10331165, "stId" : "R-CFA-5607761", "displayName" : "Dectin-1 mediated noncanonical NF-kB signaling", "events" : [ 10288908, 10288940, 10288925, 10289006, 10288936, 10288901, 10288933, 10288903 ] } ] }