{
  "dbId" : 10994013,
  "stableId" : "R-CEL-194068",
  "displayName" : "Bile acid and bile salt metabolism",
  "nodes" : [ {
    "id" : 108545,
    "reactomeId" : 193453,
    "displayName" : "chenodeoxycholate bile salts",
    "schemaClass" : "DefinedSet",
    "renderableClass" : "EntitySet",
    "position" : {
      "x" : 4514,
      "y" : 894
    },
    "minX" : 4422,
    "maxX" : 4576,
    "minY" : 876,
    "maxY" : 937,
    "prop" : {
      "x" : 4453,
      "y" : 876,
      "width" : 123,
      "height" : 37
    },
    "textPosition" : {
      "x" : 4453,
      "y" : 877
    },
    "connectors" : [ {
      "edgeId" : 108543,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 4474,
          "y" : 919
        },
        "to" : {
          "x" : 4422,
          "y" : 937
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 4469,
          "y" : 925
        },
        "b" : {
          "x" : 4474,
          "y" : 919
        },
        "c" : {
          "x" : 4466,
          "y" : 917
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 4466,
          "y" : 917
        }
      }
    } ]
  }, {
    "id" : 108544,
    "reactomeId" : 193472,
    "displayName" : "chenodeoxycholoyl-CoA",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 4241,
      "y" : 902
    },
    "minX" : 4177,
    "maxX" : 4307,
    "minY" : 879,
    "maxY" : 936,
    "prop" : {
      "x" : 4177,
      "y" : 880,
      "width" : 129,
      "height" : 45
    },
    "textPosition" : {
      "x" : 4178,
      "y" : 885
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 4301,
          "y" : 885
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 4301,
          "y" : 885
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 108543,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 4278,
          "y" : 928
        },
        "to" : {
          "x" : 4297,
          "y" : 936
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 108547,
    "reactomeId" : 193745,
    "displayName" : "4CHOL7a,12a,24(S)TONE",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 688,
      "y" : 585
    },
    "minX" : 622,
    "maxX" : 904,
    "minY" : 562,
    "maxY" : 608,
    "prop" : {
      "x" : 622,
      "y" : 563,
      "width" : 133,
      "height" : 45
    },
    "textPosition" : {
      "x" : 623,
      "y" : 568
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 750,
          "y" : 568
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 750,
          "y" : 568
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 108546,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 758,
          "y" : 584
        },
        "to" : {
          "x" : 904,
          "y" : 584
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 108549,
    "reactomeId" : 70106,
    "displayName" : "H+",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 912,
      "y" : 520
    },
    "minX" : 895,
    "maxX" : 930,
    "minY" : 433,
    "maxY" : 584,
    "prop" : {
      "x" : 895,
      "y" : 505,
      "width" : 34,
      "height" : 31
    },
    "textPosition" : {
      "x" : 898,
      "y" : 510
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 924,
          "y" : 510
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 924,
          "y" : 510
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 108546,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 910,
          "y" : 539
        },
        "to" : {
          "x" : 904,
          "y" : 584
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 108553,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 910,
          "y" : 502
        },
        "to" : {
          "x" : 903,
          "y" : 433
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ],
    "trivial" : true
  }, {
    "id" : 108548,
    "reactomeId" : 29364,
    "displayName" : "NADPH",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 858,
      "y" : 519
    },
    "minX" : 829,
    "maxX" : 904,
    "minY" : 433,
    "maxY" : 584,
    "prop" : {
      "x" : 829,
      "y" : 504,
      "width" : 59,
      "height" : 31
    },
    "textPosition" : {
      "x" : 833,
      "y" : 509
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 883,
          "y" : 509
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 883,
          "y" : 509
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 108546,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 868,
          "y" : 538
        },
        "to" : {
          "x" : 904,
          "y" : 584
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 108553,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 866,
          "y" : 501
        },
        "to" : {
          "x" : 903,
          "y" : 433
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 108551,
    "reactomeId" : 29366,
    "displayName" : "NADP+",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 1078,
      "y" : 519
    },
    "minX" : 1015,
    "maxX" : 1108,
    "minY" : 462,
    "maxY" : 567,
    "prop" : {
      "x" : 1049,
      "y" : 504,
      "width" : 58,
      "height" : 31
    },
    "textPosition" : {
      "x" : 1052,
      "y" : 509
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1102,
          "y" : 509
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1102,
          "y" : 509
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 108546,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 1057,
          "y" : 538
        },
        "to" : {
          "x" : 1015,
          "y" : 567
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 1054,
          "y" : 545
        },
        "b" : {
          "x" : 1057,
          "y" : 538
        },
        "c" : {
          "x" : 1049,
          "y" : 539
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 1049,
          "y" : 539
        }
      }
    }, {
      "edgeId" : 108553,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 1062,
          "y" : 501
        },
        "to" : {
          "x" : 1022,
          "y" : 462
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 1054,
          "y" : 499
        },
        "b" : {
          "x" : 1062,
          "y" : 501
        },
        "c" : {
          "x" : 1060,
          "y" : 493
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 1060,
          "y" : 493
        }
      }
    } ]
  }, {
    "id" : 108550,
    "reactomeId" : 193707,
    "displayName" : "5beta-cholestan-7alpha,12alpha,24(S)-triol-3-one",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 1108,
      "y" : 567
    },
    "minX" : 1015,
    "maxX" : 1200,
    "minY" : 537,
    "maxY" : 597,
    "prop" : {
      "x" : 1044,
      "y" : 538,
      "width" : 129,
      "height" : 59
    },
    "textPosition" : {
      "x" : 1045,
      "y" : 543
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1168,
          "y" : 543
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1168,
          "y" : 543
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 108546,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 1041,
          "y" : 567
        },
        "to" : {
          "x" : 1015,
          "y" : 567
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 1034,
          "y" : 571
        },
        "b" : {
          "x" : 1041,
          "y" : 567
        },
        "c" : {
          "x" : 1034,
          "y" : 563
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 1034,
          "y" : 563
        }
      }
    }, {
      "edgeId" : 108556,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1176,
          "y" : 567
        },
        "to" : {
          "x" : 1200,
          "y" : 568
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 108552,
    "reactomeId" : 10926717,
    "displayName" : "Homologues of AKR1D1",
    "schemaClass" : "DefinedSet",
    "renderableClass" : "EntitySet",
    "position" : {
      "x" : 987,
      "y" : 519
    },
    "minX" : 958,
    "maxX" : 1016,
    "minY" : 469,
    "maxY" : 560,
    "prop" : {
      "x" : 958,
      "y" : 508,
      "width" : 58,
      "height" : 23
    },
    "textPosition" : {
      "x" : 958,
      "y" : 495
    },
    "connectors" : [ {
      "edgeId" : 108546,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 988,
          "y" : 534
        },
        "to" : {
          "x" : 991,
          "y" : 552
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 991,
          "y" : 556
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 991,
          "y" : 556
        }
      }
    }, {
      "edgeId" : 108553,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 988,
          "y" : 505
        },
        "to" : {
          "x" : 992,
          "y" : 477
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 992,
          "y" : 473
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 992,
          "y" : 473
        }
      }
    } ]
  }, {
    "id" : 108555,
    "reactomeId" : 193760,
    "displayName" : "5beta-cholestan-7alpha,24(S)-diol-3-one",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 1105,
      "y" : 465
    },
    "minX" : 1022,
    "maxX" : 1203,
    "minY" : 435,
    "maxY" : 495,
    "prop" : {
      "x" : 1039,
      "y" : 436,
      "width" : 132,
      "height" : 59
    },
    "textPosition" : {
      "x" : 1039,
      "y" : 441
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1166,
          "y" : 441
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1166,
          "y" : 441
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 108553,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 1036,
          "y" : 462
        },
        "to" : {
          "x" : 1022,
          "y" : 462
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 1029,
          "y" : 466
        },
        "b" : {
          "x" : 1036,
          "y" : 462
        },
        "c" : {
          "x" : 1029,
          "y" : 458
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 1029,
          "y" : 458
        }
      }
    }, {
      "edgeId" : 108562,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1174,
          "y" : 466
        },
        "to" : {
          "x" : 1203,
          "y" : 467
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 108554,
    "reactomeId" : 193724,
    "displayName" : "4CHOL7a,24(S)DONE",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 688,
      "y" : 405
    },
    "minX" : 635,
    "maxX" : 903,
    "minY" : 382,
    "maxY" : 433,
    "prop" : {
      "x" : 635,
      "y" : 383,
      "width" : 106,
      "height" : 45
    },
    "textPosition" : {
      "x" : 637,
      "y" : 388
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 736,
          "y" : 388
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 736,
          "y" : 388
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 108553,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 744,
          "y" : 411
        },
        "to" : {
          "x" : 903,
          "y" : 433
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 108557,
    "reactomeId" : 29364,
    "displayName" : "NADPH",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 1143,
      "y" : 519
    },
    "minX" : 1114,
    "maxX" : 1203,
    "minY" : 467,
    "maxY" : 568,
    "prop" : {
      "x" : 1114,
      "y" : 504,
      "width" : 59,
      "height" : 31
    },
    "textPosition" : {
      "x" : 1118,
      "y" : 509
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1168,
          "y" : 509
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1168,
          "y" : 509
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 108556,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1161,
          "y" : 538
        },
        "to" : {
          "x" : 1200,
          "y" : 568
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 108562,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1160,
          "y" : 501
        },
        "to" : {
          "x" : 1203,
          "y" : 467
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 108559,
    "reactomeId" : 193728,
    "displayName" : "5beta-cholestan-3alpha,7alpha,12alpha,24(S)-tetrol",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 1346,
      "y" : 618
    },
    "minX" : 1280,
    "maxX" : 1414,
    "minY" : 569,
    "maxY" : 648,
    "prop" : {
      "x" : 1280,
      "y" : 589,
      "width" : 133,
      "height" : 59
    },
    "textPosition" : {
      "x" : 1289,
      "y" : 587
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1408,
          "y" : 594
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1408,
          "y" : 594
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 108556,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 1316,
          "y" : 586
        },
        "to" : {
          "x" : 1297,
          "y" : 569
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 1308,
          "y" : 584
        },
        "b" : {
          "x" : 1316,
          "y" : 586
        },
        "c" : {
          "x" : 1314,
          "y" : 578
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 1314,
          "y" : 578
        }
      }
    } ]
  }, {
    "id" : 108558,
    "reactomeId" : 70106,
    "displayName" : "H+",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 1195,
      "y" : 519
    },
    "minX" : 1178,
    "maxX" : 1213,
    "minY" : 467,
    "maxY" : 568,
    "prop" : {
      "x" : 1178,
      "y" : 504,
      "width" : 34,
      "height" : 31
    },
    "textPosition" : {
      "x" : 1181,
      "y" : 509
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1207,
          "y" : 509
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1207,
          "y" : 509
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 108556,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1196,
          "y" : 538
        },
        "to" : {
          "x" : 1200,
          "y" : 568
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 108562,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1197,
          "y" : 501
        },
        "to" : {
          "x" : 1203,
          "y" : 467
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ],
    "trivial" : true
  }, {
    "id" : 108561,
    "reactomeId" : 10926736,
    "displayName" : "Homologues of AKR1C4",
    "schemaClass" : "DefinedSet",
    "renderableClass" : "EntitySet",
    "position" : {
      "x" : 1267,
      "y" : 517
    },
    "minX" : 1228,
    "maxX" : 1306,
    "minY" : 475,
    "maxY" : 561,
    "prop" : {
      "x" : 1228,
      "y" : 493,
      "width" : 78,
      "height" : 48
    },
    "textPosition" : {
      "x" : 1231,
      "y" : 493
    },
    "connectors" : [ {
      "edgeId" : 108556,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 1269,
          "y" : 547
        },
        "to" : {
          "x" : 1270,
          "y" : 553
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 1270,
          "y" : 557
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1270,
          "y" : 557
        }
      }
    }, {
      "edgeId" : 108562,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 1268,
          "y" : 487
        },
        "to" : {
          "x" : 1268,
          "y" : 483
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 1269,
          "y" : 479
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1269,
          "y" : 479
        }
      }
    } ]
  }, {
    "id" : 108560,
    "reactomeId" : 29366,
    "displayName" : "NADP+",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 1364,
      "y" : 517
    },
    "minX" : 1295,
    "maxX" : 1394,
    "minY" : 467,
    "maxY" : 569,
    "prop" : {
      "x" : 1335,
      "y" : 502,
      "width" : 58,
      "height" : 31
    },
    "textPosition" : {
      "x" : 1338,
      "y" : 507
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1388,
          "y" : 507
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1388,
          "y" : 507
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 108556,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 1344,
          "y" : 536
        },
        "to" : {
          "x" : 1297,
          "y" : 569
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 1341,
          "y" : 543
        },
        "b" : {
          "x" : 1344,
          "y" : 536
        },
        "c" : {
          "x" : 1336,
          "y" : 537
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 1336,
          "y" : 537
        }
      }
    }, {
      "edgeId" : 108562,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 1342,
          "y" : 499
        },
        "to" : {
          "x" : 1295,
          "y" : 467
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 1334,
          "y" : 498
        },
        "b" : {
          "x" : 1342,
          "y" : 499
        },
        "c" : {
          "x" : 1339,
          "y" : 492
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 1339,
          "y" : 492
        }
      }
    } ]
  }, {
    "id" : 108563,
    "reactomeId" : 213285,
    "displayName" : "5beta-cholestan-3alpha,7alpha,24(S)-triol",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 1345,
      "y" : 406
    },
    "minX" : 1276,
    "maxX" : 1416,
    "minY" : 376,
    "maxY" : 467,
    "prop" : {
      "x" : 1276,
      "y" : 377,
      "width" : 139,
      "height" : 59
    },
    "textPosition" : {
      "x" : 1277,
      "y" : 382
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1410,
          "y" : 382
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1410,
          "y" : 382
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 108562,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 1320,
          "y" : 439
        },
        "to" : {
          "x" : 1295,
          "y" : 467
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 1318,
          "y" : 447
        },
        "b" : {
          "x" : 1320,
          "y" : 439
        },
        "c" : {
          "x" : 1312,
          "y" : 442
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 1312,
          "y" : 442
        }
      }
    } ]
  }, {
    "id" : 108565,
    "reactomeId" : 113592,
    "displayName" : "ATP",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 2557,
      "y" : 519
    },
    "minX" : 2537,
    "maxX" : 2664,
    "minY" : 395,
    "maxY" : 655,
    "prop" : {
      "x" : 2537,
      "y" : 504,
      "width" : 40,
      "height" : 31
    },
    "textPosition" : {
      "x" : 2541,
      "y" : 509
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 2572,
          "y" : 509
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 2572,
          "y" : 509
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 108564,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 2572,
          "y" : 501
        },
        "to" : {
          "x" : 2658,
          "y" : 416
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 108573,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 2571,
          "y" : 538
        },
        "to" : {
          "x" : 2664,
          "y" : 633
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 108576,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 2567,
          "y" : 538
        },
        "to" : {
          "x" : 2653,
          "y" : 655
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 108578,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 2568,
          "y" : 501
        },
        "to" : {
          "x" : 2646,
          "y" : 395
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 108567,
    "reactomeId" : 76194,
    "displayName" : "CoA-SH",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 2642,
      "y" : 518
    },
    "minX" : 2613,
    "maxX" : 2673,
    "minY" : 395,
    "maxY" : 655,
    "prop" : {
      "x" : 2613,
      "y" : 503,
      "width" : 59,
      "height" : 31
    },
    "textPosition" : {
      "x" : 2616,
      "y" : 508
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 2667,
          "y" : 508
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 2667,
          "y" : 508
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 108564,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 2644,
          "y" : 500
        },
        "to" : {
          "x" : 2658,
          "y" : 416
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 108573,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 2644,
          "y" : 537
        },
        "to" : {
          "x" : 2664,
          "y" : 633
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 108576,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 2643,
          "y" : 537
        },
        "to" : {
          "x" : 2653,
          "y" : 655
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 108578,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 2642,
          "y" : 500
        },
        "to" : {
          "x" : 2646,
          "y" : 395
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 108566,
    "reactomeId" : 193762,
    "displayName" : "TetraHCA",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 2555,
      "y" : 618
    },
    "minX" : 2519,
    "maxX" : 2658,
    "minY" : 416,
    "maxY" : 655,
    "prop" : {
      "x" : 2519,
      "y" : 603,
      "width" : 73,
      "height" : 31
    },
    "textPosition" : {
      "x" : 2522,
      "y" : 608
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 2587,
          "y" : 608
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 2587,
          "y" : 608
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 108564,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 2562,
          "y" : 600
        },
        "to" : {
          "x" : 2658,
          "y" : 416
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 108576,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 2595,
          "y" : 631
        },
        "to" : {
          "x" : 2653,
          "y" : 655
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 108569,
    "reactomeId" : 29356,
    "displayName" : "H2O",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 2844,
      "y" : 519
    },
    "minX" : 2793,
    "maxX" : 2867,
    "minY" : 391,
    "maxY" : 656,
    "prop" : {
      "x" : 2823,
      "y" : 504,
      "width" : 43,
      "height" : 31
    },
    "textPosition" : {
      "x" : 2827,
      "y" : 509
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 2861,
          "y" : 509
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 2861,
          "y" : 509
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 108564,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 2836,
          "y" : 501
        },
        "to" : {
          "x" : 2793,
          "y" : 416
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 2829,
          "y" : 497
        },
        "b" : {
          "x" : 2836,
          "y" : 501
        },
        "c" : {
          "x" : 2836,
          "y" : 493
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 2836,
          "y" : 493
        }
      }
    }, {
      "edgeId" : 108573,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 2839,
          "y" : 538
        },
        "to" : {
          "x" : 2807,
          "y" : 634
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 2841,
          "y" : 546
        },
        "b" : {
          "x" : 2839,
          "y" : 538
        },
        "c" : {
          "x" : 2833,
          "y" : 543
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 2833,
          "y" : 543
        }
      }
    }, {
      "edgeId" : 108576,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 2845,
          "y" : 538
        },
        "to" : {
          "x" : 2855,
          "y" : 656
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 2850,
          "y" : 545
        },
        "b" : {
          "x" : 2845,
          "y" : 538
        },
        "c" : {
          "x" : 2842,
          "y" : 545
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 2842,
          "y" : 545
        }
      }
    }, {
      "edgeId" : 108578,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 2840,
          "y" : 501
        },
        "to" : {
          "x" : 2815,
          "y" : 391
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 2835,
          "y" : 495
        },
        "b" : {
          "x" : 2840,
          "y" : 501
        },
        "c" : {
          "x" : 2842,
          "y" : 493
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 2842,
          "y" : 493
        }
      }
    } ],
    "trivial" : true
  }, {
    "id" : 108568,
    "reactomeId" : 193741,
    "displayName" : "25(R) TetraHCA-CoA",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 2972,
      "y" : 447
    },
    "minX" : 2793,
    "maxX" : 3028,
    "minY" : 416,
    "maxY" : 656,
    "prop" : {
      "x" : 2917,
      "y" : 427,
      "width" : 110,
      "height" : 40
    },
    "textPosition" : {
      "x" : 2918,
      "y" : 429
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 3022,
          "y" : 432
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 3022,
          "y" : 432
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 108564,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 2914,
          "y" : 437
        },
        "to" : {
          "x" : 2793,
          "y" : 416
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 2906,
          "y" : 440
        },
        "b" : {
          "x" : 2914,
          "y" : 437
        },
        "c" : {
          "x" : 2908,
          "y" : 432
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 2908,
          "y" : 432
        }
      }
    }, {
      "edgeId" : 108576,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 2960,
          "y" : 470
        },
        "to" : {
          "x" : 2855,
          "y" : 656
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 2960,
          "y" : 478
        },
        "b" : {
          "x" : 2960,
          "y" : 470
        },
        "c" : {
          "x" : 2953,
          "y" : 474
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 2953,
          "y" : 474
        }
      }
    } ]
  }, {
    "id" : 108571,
    "reactomeId" : 111294,
    "displayName" : "PPi",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 2982,
      "y" : 527
    },
    "minX" : 2793,
    "maxX" : 3000,
    "minY" : 391,
    "maxY" : 656,
    "prop" : {
      "x" : 2965,
      "y" : 512,
      "width" : 34,
      "height" : 31
    },
    "textPosition" : {
      "x" : 2968,
      "y" : 517
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 2994,
          "y" : 517
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 2994,
          "y" : 517
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 108564,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 2962,
          "y" : 517
        },
        "to" : {
          "x" : 2793,
          "y" : 416
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 2954,
          "y" : 517
        },
        "b" : {
          "x" : 2962,
          "y" : 517
        },
        "c" : {
          "x" : 2958,
          "y" : 510
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 2958,
          "y" : 510
        }
      }
    }, {
      "edgeId" : 108573,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 2962,
          "y" : 537
        },
        "to" : {
          "x" : 2807,
          "y" : 634
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 2958,
          "y" : 544
        },
        "b" : {
          "x" : 2962,
          "y" : 537
        },
        "c" : {
          "x" : 2954,
          "y" : 537
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 2954,
          "y" : 537
        }
      }
    }, {
      "edgeId" : 108576,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 2966,
          "y" : 546
        },
        "to" : {
          "x" : 2855,
          "y" : 656
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 2964,
          "y" : 554
        },
        "b" : {
          "x" : 2966,
          "y" : 546
        },
        "c" : {
          "x" : 2958,
          "y" : 548
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 2958,
          "y" : 548
        }
      }
    }, {
      "edgeId" : 108578,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 2962,
          "y" : 513
        },
        "to" : {
          "x" : 2815,
          "y" : 391
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 2954,
          "y" : 512
        },
        "b" : {
          "x" : 2962,
          "y" : 513
        },
        "c" : {
          "x" : 2959,
          "y" : 505
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 2959,
          "y" : 505
        }
      }
    } ]
  }, {
    "id" : 108570,
    "reactomeId" : 76577,
    "displayName" : "AMP",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 2891,
      "y" : 519
    },
    "minX" : 2793,
    "maxX" : 2913,
    "minY" : 391,
    "maxY" : 656,
    "prop" : {
      "x" : 2870,
      "y" : 504,
      "width" : 42,
      "height" : 31
    },
    "textPosition" : {
      "x" : 2874,
      "y" : 509
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 2907,
          "y" : 509
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 2907,
          "y" : 509
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 108564,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 2876,
          "y" : 501
        },
        "to" : {
          "x" : 2793,
          "y" : 416
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 2868,
          "y" : 499
        },
        "b" : {
          "x" : 2876,
          "y" : 501
        },
        "c" : {
          "x" : 2874,
          "y" : 493
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 2874,
          "y" : 493
        }
      }
    }, {
      "edgeId" : 108573,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 2879,
          "y" : 538
        },
        "to" : {
          "x" : 2807,
          "y" : 634
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 2878,
          "y" : 546
        },
        "b" : {
          "x" : 2879,
          "y" : 538
        },
        "c" : {
          "x" : 2872,
          "y" : 541
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 2872,
          "y" : 541
        }
      }
    }, {
      "edgeId" : 108576,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 2886,
          "y" : 538
        },
        "to" : {
          "x" : 2855,
          "y" : 656
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 2888,
          "y" : 546
        },
        "b" : {
          "x" : 2886,
          "y" : 538
        },
        "c" : {
          "x" : 2880,
          "y" : 544
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 2880,
          "y" : 544
        }
      }
    }, {
      "edgeId" : 108578,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 2881,
          "y" : 501
        },
        "to" : {
          "x" : 2815,
          "y" : 391
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 2874,
          "y" : 497
        },
        "b" : {
          "x" : 2881,
          "y" : 501
        },
        "c" : {
          "x" : 2881,
          "y" : 493
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 2881,
          "y" : 493
        }
      }
    } ]
  }, {
    "id" : 108572,
    "reactomeId" : 10922675,
    "displayName" : "Homologues of SLC27A5",
    "schemaClass" : "DefinedSet",
    "renderableClass" : "EntitySet",
    "position" : {
      "x" : 2780,
      "y" : 487
    },
    "minX" : 2750,
    "maxX" : 2811,
    "minY" : 423,
    "maxY" : 623,
    "prop" : {
      "x" : 2750,
      "y" : 476,
      "width" : 61,
      "height" : 23
    },
    "textPosition" : {
      "x" : 2751,
      "y" : 456
    },
    "connectors" : [ {
      "edgeId" : 108564,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 2775,
          "y" : 473
        },
        "to" : {
          "x" : 2760,
          "y" : 431
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 2759,
          "y" : 427
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 2759,
          "y" : 427
        }
      }
    }, {
      "edgeId" : 108573,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 2780,
          "y" : 502
        },
        "to" : {
          "x" : 2788,
          "y" : 615
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 2788,
          "y" : 619
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 2788,
          "y" : 619
        }
      }
    } ]
  }, {
    "id" : 108575,
    "reactomeId" : 193739,
    "displayName" : "3,7,24THCA-CoA",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 2980,
      "y" : 603
    },
    "minX" : 2807,
    "maxX" : 3032,
    "minY" : 391,
    "maxY" : 634,
    "prop" : {
      "x" : 2930,
      "y" : 584,
      "width" : 101,
      "height" : 39
    },
    "textPosition" : {
      "x" : 2938,
      "y" : 586
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 3026,
          "y" : 589
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 3026,
          "y" : 589
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 108573,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 2927,
          "y" : 612
        },
        "to" : {
          "x" : 2807,
          "y" : 634
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 2921,
          "y" : 617
        },
        "b" : {
          "x" : 2927,
          "y" : 612
        },
        "c" : {
          "x" : 2919,
          "y" : 609
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 2919,
          "y" : 609
        }
      }
    }, {
      "edgeId" : 108578,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 2964,
          "y" : 581
        },
        "to" : {
          "x" : 2815,
          "y" : 391
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 2957,
          "y" : 578
        },
        "b" : {
          "x" : 2964,
          "y" : 581
        },
        "c" : {
          "x" : 2963,
          "y" : 573
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 2963,
          "y" : 573
        }
      }
    } ]
  }, {
    "id" : 108574,
    "reactomeId" : 193778,
    "displayName" : "3,7,24THCA",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 2560,
      "y" : 432
    },
    "minX" : 2515,
    "maxX" : 2664,
    "minY" : 395,
    "maxY" : 633,
    "prop" : {
      "x" : 2515,
      "y" : 417,
      "width" : 90,
      "height" : 31
    },
    "textPosition" : {
      "x" : 2520,
      "y" : 422
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 2600,
          "y" : 422
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 2600,
          "y" : 422
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 108573,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 2568,
          "y" : 451
        },
        "to" : {
          "x" : 2664,
          "y" : 633
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 108578,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 2596,
          "y" : 414
        },
        "to" : {
          "x" : 2646,
          "y" : 395
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 108577,
    "reactomeId" : 10926920,
    "displayName" : "Homologues of SLC27A2",
    "schemaClass" : "DefinedSet",
    "renderableClass" : "EntitySet",
    "position" : {
      "x" : 2703,
      "y" : 551
    },
    "minX" : 2673,
    "maxX" : 2734,
    "minY" : 401,
    "maxY" : 648,
    "prop" : {
      "x" : 2673,
      "y" : 540,
      "width" : 61,
      "height" : 23
    },
    "textPosition" : {
      "x" : 2674,
      "y" : 520
    },
    "connectors" : [ {
      "edgeId" : 108576,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 2702,
          "y" : 566
        },
        "to" : {
          "x" : 2700,
          "y" : 640
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 2699,
          "y" : 644
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 2699,
          "y" : 644
        }
      }
    }, {
      "edgeId" : 108578,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 2703,
          "y" : 537
        },
        "to" : {
          "x" : 2703,
          "y" : 409
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 2703,
          "y" : 405
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 2703,
          "y" : 405
        }
      }
    } ]
  }, {
    "id" : 108580,
    "reactomeId" : 193793,
    "displayName" : "25(R) TetraHCA-CoA",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 3143,
      "y" : 462
    },
    "minX" : 3097,
    "maxX" : 3190,
    "minY" : 438,
    "maxY" : 485,
    "prop" : {
      "x" : 3097,
      "y" : 439,
      "width" : 92,
      "height" : 46
    },
    "textPosition" : {
      "x" : 3108,
      "y" : 438
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 3184,
          "y" : 444
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 3184,
          "y" : 444
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 108579,
      "type" : "INPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 108582,
    "reactomeId" : 193732,
    "displayName" : "3,7,24THCA-CoA",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 3270,
      "y" : 583
    },
    "minX" : 3236,
    "maxX" : 3306,
    "minY" : 558,
    "maxY" : 608,
    "prop" : {
      "x" : 3236,
      "y" : 559,
      "width" : 69,
      "height" : 49
    },
    "textPosition" : {
      "x" : 3236,
      "y" : 566
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 3300,
          "y" : 564
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 3300,
          "y" : 564
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 108581,
      "type" : "INPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 108581,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 108585,
    "reactomeId" : 70106,
    "displayName" : "H+",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 935,
      "y" : 1239
    },
    "minX" : 918,
    "maxX" : 955,
    "minY" : 1179,
    "maxY" : 1309,
    "prop" : {
      "x" : 918,
      "y" : 1224,
      "width" : 34,
      "height" : 31
    },
    "textPosition" : {
      "x" : 921,
      "y" : 1229
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 947,
          "y" : 1229
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 947,
          "y" : 1229
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 108583,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 940,
          "y" : 1221
        },
        "to" : {
          "x" : 955,
          "y" : 1179
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 108590,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 938,
          "y" : 1258
        },
        "to" : {
          "x" : 950,
          "y" : 1309
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ],
    "trivial" : true
  }, {
    "id" : 108584,
    "reactomeId" : 9617026,
    "displayName" : "4CHOL7a,12a,27TONE",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 705,
      "y" : 1135
    },
    "minX" : 654,
    "maxX" : 955,
    "minY" : 1112,
    "maxY" : 1179,
    "prop" : {
      "x" : 654,
      "y" : 1113,
      "width" : 103,
      "height" : 45
    },
    "textPosition" : {
      "x" : 657,
      "y" : 1118
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 752,
          "y" : 1118
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 752,
          "y" : 1118
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 108583,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 760,
          "y" : 1144
        },
        "to" : {
          "x" : 955,
          "y" : 1179
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 108587,
    "reactomeId" : 193829,
    "displayName" : "5beta-cholestan-7alpha,12alpha,27-triol-3-one",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 1123,
      "y" : 1177
    },
    "minX" : 1030,
    "maxX" : 1213,
    "minY" : 1147,
    "maxY" : 1207,
    "prop" : {
      "x" : 1057,
      "y" : 1148,
      "width" : 133,
      "height" : 59
    },
    "textPosition" : {
      "x" : 1058,
      "y" : 1153
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1185,
          "y" : 1153
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1185,
          "y" : 1153
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 108583,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 1054,
          "y" : 1177
        },
        "to" : {
          "x" : 1030,
          "y" : 1178
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 1047,
          "y" : 1181
        },
        "b" : {
          "x" : 1054,
          "y" : 1177
        },
        "c" : {
          "x" : 1047,
          "y" : 1173
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 1047,
          "y" : 1173
        }
      }
    }, {
      "edgeId" : 108593,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1193,
          "y" : 1177
        },
        "to" : {
          "x" : 1213,
          "y" : 1178
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 108586,
    "reactomeId" : 29364,
    "displayName" : "NADPH",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 883,
      "y" : 1239
    },
    "minX" : 854,
    "maxX" : 955,
    "minY" : 1179,
    "maxY" : 1309,
    "prop" : {
      "x" : 854,
      "y" : 1224,
      "width" : 59,
      "height" : 31
    },
    "textPosition" : {
      "x" : 858,
      "y" : 1229
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 908,
          "y" : 1229
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 908,
          "y" : 1229
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 108583,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 901,
          "y" : 1221
        },
        "to" : {
          "x" : 955,
          "y" : 1179
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 108590,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 897,
          "y" : 1258
        },
        "to" : {
          "x" : 950,
          "y" : 1309
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 108589,
    "reactomeId" : 10926717,
    "displayName" : "Homologues of AKR1D1",
    "schemaClass" : "DefinedSet",
    "renderableClass" : "EntitySet",
    "position" : {
      "x" : 993,
      "y" : 1238
    },
    "minX" : 964,
    "maxX" : 1022,
    "minY" : 1187,
    "maxY" : 1301,
    "prop" : {
      "x" : 964,
      "y" : 1227,
      "width" : 58,
      "height" : 23
    },
    "textPosition" : {
      "x" : 964,
      "y" : 1214
    },
    "connectors" : [ {
      "edgeId" : 108583,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 993,
          "y" : 1224
        },
        "to" : {
          "x" : 994,
          "y" : 1195
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 994,
          "y" : 1191
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 994,
          "y" : 1191
        }
      }
    }, {
      "edgeId" : 108590,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 993,
          "y" : 1253
        },
        "to" : {
          "x" : 994,
          "y" : 1293
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 995,
          "y" : 1297
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 995,
          "y" : 1297
        }
      }
    } ]
  }, {
    "id" : 108588,
    "reactomeId" : 29366,
    "displayName" : "NADP+",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 1081,
      "y" : 1238
    },
    "minX" : 1020,
    "maxX" : 1111,
    "minY" : 1178,
    "maxY" : 1309,
    "prop" : {
      "x" : 1052,
      "y" : 1223,
      "width" : 58,
      "height" : 31
    },
    "textPosition" : {
      "x" : 1055,
      "y" : 1228
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1105,
          "y" : 1228
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1105,
          "y" : 1228
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 108583,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 1067,
          "y" : 1220
        },
        "to" : {
          "x" : 1030,
          "y" : 1178
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 1059,
          "y" : 1217
        },
        "b" : {
          "x" : 1067,
          "y" : 1220
        },
        "c" : {
          "x" : 1065,
          "y" : 1212
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 1065,
          "y" : 1212
        }
      }
    }, {
      "edgeId" : 108590,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 1067,
          "y" : 1257
        },
        "to" : {
          "x" : 1020,
          "y" : 1309
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 1065,
          "y" : 1265
        },
        "b" : {
          "x" : 1067,
          "y" : 1257
        },
        "c" : {
          "x" : 1059,
          "y" : 1259
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 1059,
          "y" : 1259
        }
      }
    } ]
  }, {
    "id" : 108591,
    "reactomeId" : 193835,
    "displayName" : "4CHOL7a,27DONE",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 696,
      "y" : 1314
    },
    "minX" : 633,
    "maxX" : 950,
    "minY" : 1298,
    "maxY" : 1330,
    "prop" : {
      "x" : 633,
      "y" : 1299,
      "width" : 126,
      "height" : 31
    },
    "textPosition" : {
      "x" : 636,
      "y" : 1304
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 754,
          "y" : 1304
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 754,
          "y" : 1304
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 108590,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 762,
          "y" : 1312
        },
        "to" : {
          "x" : 950,
          "y" : 1309
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 108592,
    "reactomeId" : 193830,
    "displayName" : "5beta-cholestan-7alpha,27-diol-3-one",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 1113,
      "y" : 1311
    },
    "minX" : 1020,
    "maxX" : 1207,
    "minY" : 1288,
    "maxY" : 1334,
    "prop" : {
      "x" : 1044,
      "y" : 1289,
      "width" : 139,
      "height" : 45
    },
    "textPosition" : {
      "x" : 1045,
      "y" : 1294
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1178,
          "y" : 1294
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1178,
          "y" : 1294
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 108590,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 1041,
          "y" : 1309
        },
        "to" : {
          "x" : 1020,
          "y" : 1309
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 1034,
          "y" : 1313
        },
        "b" : {
          "x" : 1041,
          "y" : 1309
        },
        "c" : {
          "x" : 1034,
          "y" : 1305
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 1034,
          "y" : 1305
        }
      }
    }, {
      "edgeId" : 108599,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1186,
          "y" : 1309
        },
        "to" : {
          "x" : 1207,
          "y" : 1309
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 108595,
    "reactomeId" : 29364,
    "displayName" : "NADPH",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 1144,
      "y" : 1237
    },
    "minX" : 1115,
    "maxX" : 1213,
    "minY" : 1178,
    "maxY" : 1309,
    "prop" : {
      "x" : 1115,
      "y" : 1222,
      "width" : 59,
      "height" : 31
    },
    "textPosition" : {
      "x" : 1119,
      "y" : 1227
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1169,
          "y" : 1227
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1169,
          "y" : 1227
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 108593,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1162,
          "y" : 1219
        },
        "to" : {
          "x" : 1213,
          "y" : 1178
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 108599,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1157,
          "y" : 1256
        },
        "to" : {
          "x" : 1207,
          "y" : 1309
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 108594,
    "reactomeId" : 70106,
    "displayName" : "H+",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 1194,
      "y" : 1239
    },
    "minX" : 1177,
    "maxX" : 1213,
    "minY" : 1178,
    "maxY" : 1309,
    "prop" : {
      "x" : 1177,
      "y" : 1224,
      "width" : 34,
      "height" : 31
    },
    "textPosition" : {
      "x" : 1180,
      "y" : 1229
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1206,
          "y" : 1229
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1206,
          "y" : 1229
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 108593,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1198,
          "y" : 1221
        },
        "to" : {
          "x" : 1213,
          "y" : 1178
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 108599,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1196,
          "y" : 1258
        },
        "to" : {
          "x" : 1207,
          "y" : 1309
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ],
    "trivial" : true
  }, {
    "id" : 108597,
    "reactomeId" : 29366,
    "displayName" : "NADP+",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 1348,
      "y" : 1234
    },
    "minX" : 1278,
    "maxX" : 1378,
    "minY" : 1177,
    "maxY" : 1308,
    "prop" : {
      "x" : 1319,
      "y" : 1219,
      "width" : 58,
      "height" : 31
    },
    "textPosition" : {
      "x" : 1322,
      "y" : 1224
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1372,
          "y" : 1224
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1372,
          "y" : 1224
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 108593,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 1328,
          "y" : 1216
        },
        "to" : {
          "x" : 1278,
          "y" : 1177
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 1320,
          "y" : 1215
        },
        "b" : {
          "x" : 1328,
          "y" : 1216
        },
        "c" : {
          "x" : 1325,
          "y" : 1209
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 1325,
          "y" : 1209
        }
      }
    }, {
      "edgeId" : 108599,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 1333,
          "y" : 1253
        },
        "to" : {
          "x" : 1278,
          "y" : 1308
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 1331,
          "y" : 1261
        },
        "b" : {
          "x" : 1333,
          "y" : 1253
        },
        "c" : {
          "x" : 1325,
          "y" : 1255
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 1325,
          "y" : 1255
        }
      }
    } ]
  }, {
    "id" : 108596,
    "reactomeId" : 193843,
    "displayName" : "5beta-cholestan-3alpha,7alpha,12alpha,27-tetrol",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 1369,
      "y" : 1170
    },
    "minX" : 1278,
    "maxX" : 1430,
    "minY" : 1140,
    "maxY" : 1200,
    "prop" : {
      "x" : 1310,
      "y" : 1141,
      "width" : 119,
      "height" : 59
    },
    "textPosition" : {
      "x" : 1311,
      "y" : 1146
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1424,
          "y" : 1146
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1424,
          "y" : 1146
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 108593,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 1307,
          "y" : 1174
        },
        "to" : {
          "x" : 1278,
          "y" : 1177
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 1301,
          "y" : 1179
        },
        "b" : {
          "x" : 1307,
          "y" : 1174
        },
        "c" : {
          "x" : 1300,
          "y" : 1171
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 1300,
          "y" : 1171
        }
      }
    } ]
  }, {
    "id" : 108598,
    "reactomeId" : 10926736,
    "displayName" : "Homologues of AKR1C4",
    "schemaClass" : "DefinedSet",
    "renderableClass" : "EntitySet",
    "position" : {
      "x" : 1260,
      "y" : 1235
    },
    "minX" : 1224,
    "maxX" : 1296,
    "minY" : 1185,
    "maxY" : 1301,
    "prop" : {
      "x" : 1224,
      "y" : 1214,
      "width" : 72,
      "height" : 42
    },
    "textPosition" : {
      "x" : 1224,
      "y" : 1211
    },
    "connectors" : [ {
      "edgeId" : 108593,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 1260,
          "y" : 1208
        },
        "to" : {
          "x" : 1260,
          "y" : 1193
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 1260,
          "y" : 1189
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1260,
          "y" : 1189
        }
      }
    }, {
      "edgeId" : 108599,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 1260,
          "y" : 1262
        },
        "to" : {
          "x" : 1260,
          "y" : 1293
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 1260,
          "y" : 1297
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1260,
          "y" : 1297
        }
      }
    } ]
  }, {
    "id" : 108600,
    "reactomeId" : 193842,
    "displayName" : "5beta-cholestan-3alpha,7alpha,26-triol",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 1364,
      "y" : 1312
    },
    "minX" : 1278,
    "maxX" : 1428,
    "minY" : 1282,
    "maxY" : 1342,
    "prop" : {
      "x" : 1302,
      "y" : 1283,
      "width" : 125,
      "height" : 59
    },
    "textPosition" : {
      "x" : 1303,
      "y" : 1288
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1422,
          "y" : 1288
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1422,
          "y" : 1288
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 108599,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 1299,
          "y" : 1309
        },
        "to" : {
          "x" : 1278,
          "y" : 1308
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 1292,
          "y" : 1313
        },
        "b" : {
          "x" : 1299,
          "y" : 1309
        },
        "c" : {
          "x" : 1292,
          "y" : 1305
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 1292,
          "y" : 1305
        }
      }
    } ]
  }, {
    "id" : 108603,
    "reactomeId" : 70106,
    "displayName" : "H+",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 329,
      "y" : 924
    },
    "minX" : 289,
    "maxX" : 347,
    "minY" : 890,
    "maxY" : 940,
    "prop" : {
      "x" : 312,
      "y" : 909,
      "width" : 34,
      "height" : 31
    },
    "textPosition" : {
      "x" : 315,
      "y" : 914
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 341,
          "y" : 914
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 341,
          "y" : 914
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 108601,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 309,
          "y" : 909
        },
        "to" : {
          "x" : 289,
          "y" : 890
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ],
    "trivial" : true
  }, {
    "id" : 108602,
    "reactomeId" : 176478,
    "displayName" : "CHOL",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 223,
      "y" : 916
    },
    "minX" : 199,
    "maxX" : 289,
    "minY" : 890,
    "maxY" : 932,
    "prop" : {
      "x" : 199,
      "y" : 901,
      "width" : 49,
      "height" : 31
    },
    "textPosition" : {
      "x" : 203,
      "y" : 906
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 243,
          "y" : 906
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 243,
          "y" : 906
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 108601,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 251,
          "y" : 906
        },
        "to" : {
          "x" : 289,
          "y" : 890
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 108605,
    "reactomeId" : 29368,
    "displayName" : "O2",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 279,
      "y" : 933
    },
    "minX" : 262,
    "maxX" : 297,
    "minY" : 890,
    "maxY" : 949,
    "prop" : {
      "x" : 262,
      "y" : 918,
      "width" : 34,
      "height" : 31
    },
    "textPosition" : {
      "x" : 266,
      "y" : 923
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 291,
          "y" : 923
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 291,
          "y" : 923
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 108601,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 282,
          "y" : 915
        },
        "to" : {
          "x" : 289,
          "y" : 890
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ],
    "trivial" : true
  }, {
    "id" : 108604,
    "reactomeId" : 29364,
    "displayName" : "NADPH",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 340,
      "y" : 889
    },
    "minX" : 289,
    "maxX" : 371,
    "minY" : 873,
    "maxY" : 905,
    "prop" : {
      "x" : 311,
      "y" : 874,
      "width" : 59,
      "height" : 31
    },
    "textPosition" : {
      "x" : 315,
      "y" : 879
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 365,
          "y" : 879
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 365,
          "y" : 879
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 108601,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 308,
          "y" : 889
        },
        "to" : {
          "x" : 289,
          "y" : 890
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 108607,
    "reactomeId" : 192148,
    "displayName" : "25OH-CHOL",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 290,
      "y" : 758
    },
    "minX" : 247,
    "maxX" : 335,
    "minY" : 742,
    "maxY" : 808,
    "prop" : {
      "x" : 247,
      "y" : 743,
      "width" : 87,
      "height" : 31
    },
    "textPosition" : {
      "x" : 251,
      "y" : 748
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 329,
          "y" : 748
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 329,
          "y" : 748
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 108601,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 289,
          "y" : 777
        },
        "to" : {
          "x" : 289,
          "y" : 808
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 293,
          "y" : 784
        },
        "b" : {
          "x" : 289,
          "y" : 777
        },
        "c" : {
          "x" : 285,
          "y" : 784
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 285,
          "y" : 784
        }
      }
    } ]
  }, {
    "id" : 108606,
    "reactomeId" : 29356,
    "displayName" : "H2O",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 243,
      "y" : 803
    },
    "minX" : 222,
    "maxX" : 289,
    "minY" : 787,
    "maxY" : 819,
    "prop" : {
      "x" : 222,
      "y" : 788,
      "width" : 43,
      "height" : 31
    },
    "textPosition" : {
      "x" : 226,
      "y" : 793
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 260,
          "y" : 793
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 260,
          "y" : 793
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 108601,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 268,
          "y" : 805
        },
        "to" : {
          "x" : 289,
          "y" : 808
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 275,
          "y" : 802
        },
        "b" : {
          "x" : 268,
          "y" : 805
        },
        "c" : {
          "x" : 274,
          "y" : 810
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 274,
          "y" : 810
        }
      }
    } ],
    "trivial" : true
  }, {
    "id" : 108609,
    "reactomeId" : 10926677,
    "displayName" : "CH25H (Fe2+ cofactor)",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 214,
      "y" : 845
    },
    "minX" : 168,
    "maxX" : 281,
    "minY" : 821,
    "maxY" : 864,
    "prop" : {
      "x" : 168,
      "y" : 827,
      "width" : 92,
      "height" : 37
    },
    "textPosition" : {
      "x" : 166,
      "y" : 829
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 260,
          "y" : 827
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 260,
          "y" : 827
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 108601,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 263,
          "y" : 845
        },
        "to" : {
          "x" : 273,
          "y" : 845
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 277,
          "y" : 845
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 277,
          "y" : 845
        }
      }
    } ]
  }, {
    "id" : 108608,
    "reactomeId" : 29366,
    "displayName" : "NADP+",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 343,
      "y" : 789
    },
    "minX" : 289,
    "maxX" : 373,
    "minY" : 773,
    "maxY" : 808,
    "prop" : {
      "x" : 314,
      "y" : 774,
      "width" : 58,
      "height" : 31
    },
    "textPosition" : {
      "x" : 317,
      "y" : 779
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 367,
          "y" : 779
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 367,
          "y" : 779
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 108601,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 311,
          "y" : 799
        },
        "to" : {
          "x" : 289,
          "y" : 808
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 306,
          "y" : 805
        },
        "b" : {
          "x" : 311,
          "y" : 799
        },
        "c" : {
          "x" : 303,
          "y" : 798
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 303,
          "y" : 798
        }
      }
    } ]
  }, {
    "id" : 108611,
    "reactomeId" : 74113,
    "displayName" : "Na+",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 5301,
      "y" : 854
    },
    "minX" : 5235,
    "maxX" : 5323,
    "minY" : 838,
    "maxY" : 879,
    "prop" : {
      "x" : 5281,
      "y" : 839,
      "width" : 41,
      "height" : 31
    },
    "textPosition" : {
      "x" : 5284,
      "y" : 844
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 5317,
          "y" : 844
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 5317,
          "y" : 844
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 108610,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 5278,
          "y" : 861
        },
        "to" : {
          "x" : 5235,
          "y" : 879
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 108613,
    "reactomeId" : 83910,
    "displayName" : "Na+",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 5297,
      "y" : 972
    },
    "minX" : 5235,
    "maxX" : 5319,
    "minY" : 952,
    "maxY" : 988,
    "prop" : {
      "x" : 5277,
      "y" : 957,
      "width" : 41,
      "height" : 31
    },
    "textPosition" : {
      "x" : 5280,
      "y" : 962
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 5313,
          "y" : 962
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 5313,
          "y" : 962
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 108610,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 5274,
          "y" : 965
        },
        "to" : {
          "x" : 5235,
          "y" : 952
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 5266,
          "y" : 967
        },
        "b" : {
          "x" : 5274,
          "y" : 965
        },
        "c" : {
          "x" : 5269,
          "y" : 959
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 5269,
          "y" : 959
        }
      }
    } ]
  }, {
    "id" : 108612,
    "reactomeId" : 192483,
    "displayName" : "bile salts and acids",
    "schemaClass" : "DefinedSet",
    "renderableClass" : "EntitySet",
    "position" : {
      "x" : 5157,
      "y" : 844
    },
    "minX" : 5097,
    "maxX" : 5235,
    "minY" : 833,
    "maxY" : 879,
    "prop" : {
      "x" : 5097,
      "y" : 833,
      "width" : 120,
      "height" : 23
    },
    "textPosition" : {
      "x" : 5109,
      "y" : 827
    },
    "connectors" : [ {
      "edgeId" : 108610,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 5182,
          "y" : 862
        },
        "to" : {
          "x" : 5235,
          "y" : 879
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 108615,
    "reactomeId" : 10927004,
    "displayName" : "SLC10A2",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 5171,
      "y" : 914
    },
    "minX" : 5141,
    "maxX" : 5227,
    "minY" : 897,
    "maxY" : 926,
    "prop" : {
      "x" : 5141,
      "y" : 903,
      "width" : 61,
      "height" : 23
    },
    "textPosition" : {
      "x" : 5144,
      "y" : 897
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 5202,
          "y" : 903
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 5202,
          "y" : 903
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 108610,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 5205,
          "y" : 913
        },
        "to" : {
          "x" : 5219,
          "y" : 913
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 5223,
          "y" : 913
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 5223,
          "y" : 913
        }
      }
    } ]
  }, {
    "id" : 108614,
    "reactomeId" : 194156,
    "displayName" : "bile salts and acids",
    "schemaClass" : "DefinedSet",
    "renderableClass" : "EntitySet",
    "position" : {
      "x" : 5236,
      "y" : 1052
    },
    "minX" : 5104,
    "maxX" : 5296,
    "minY" : 952,
    "maxY" : 1133,
    "prop" : {
      "x" : 5176,
      "y" : 1041,
      "width" : 120,
      "height" : 23
    },
    "textPosition" : {
      "x" : 5188,
      "y" : 1035
    },
    "connectors" : [ {
      "edgeId" : 108610,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 5235,
          "y" : 1035
        },
        "to" : {
          "x" : 5235,
          "y" : 952
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 5231,
          "y" : 1028
        },
        "b" : {
          "x" : 5235,
          "y" : 1035
        },
        "c" : {
          "x" : 5239,
          "y" : 1028
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 5239,
          "y" : 1028
        }
      }
    }, {
      "edgeId" : 108661,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 5213,
          "y" : 1070
        },
        "to" : {
          "x" : 5104,
          "y" : 1118
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 108665,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 5236,
          "y" : 1070
        },
        "to" : {
          "x" : 5236,
          "y" : 1133
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 108664,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 5212,
          "y" : 1035
        },
        "to" : {
          "x" : 5107,
          "y" : 989
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 5204,
          "y" : 1036
        },
        "b" : {
          "x" : 5212,
          "y" : 1035
        },
        "c" : {
          "x" : 5207,
          "y" : 1029
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 5207,
          "y" : 1029
        }
      }
    } ]
  }, {
    "id" : 108617,
    "reactomeId" : 192483,
    "displayName" : "bile salts and acids",
    "schemaClass" : "DefinedSet",
    "renderableClass" : "EntitySet",
    "position" : {
      "x" : 4950,
      "y" : 1320
    },
    "minX" : 4822,
    "maxX" : 5239,
    "minY" : 1220,
    "maxY" : 1332,
    "prop" : {
      "x" : 4890,
      "y" : 1309,
      "width" : 120,
      "height" : 23
    },
    "textPosition" : {
      "x" : 4902,
      "y" : 1303
    },
    "connectors" : [ {
      "edgeId" : 108616,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 4913,
          "y" : 1303
        },
        "to" : {
          "x" : 4822,
          "y" : 1280
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 108622,
      "type" : "INPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 108665,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 5016,
          "y" : 1310
        },
        "to" : {
          "x" : 5213,
          "y" : 1277
        }
      }, {
        "from" : {
          "x" : 5213,
          "y" : 1277
        },
        "to" : {
          "x" : 5239,
          "y" : 1220
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 5022,
          "y" : 1305
        },
        "b" : {
          "x" : 5016,
          "y" : 1310
        },
        "c" : {
          "x" : 5023,
          "y" : 1313
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 5023,
          "y" : 1313
        }
      }
    } ]
  }, {
    "id" : 108619,
    "reactomeId" : 83910,
    "displayName" : "Na+",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 4673,
      "y" : 1228
    },
    "minX" : 4653,
    "maxX" : 4731,
    "minY" : 1212,
    "maxY" : 1279,
    "prop" : {
      "x" : 4653,
      "y" : 1213,
      "width" : 41,
      "height" : 31
    },
    "textPosition" : {
      "x" : 4656,
      "y" : 1218
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 4689,
          "y" : 1218
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 4689,
          "y" : 1218
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 108616,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 4690,
          "y" : 1247
        },
        "to" : {
          "x" : 4731,
          "y" : 1279
        }
      } ],
      "stoichiometry" : {
        "value" : 2,
        "shape" : {
          "a" : {
            "x" : 4704,
            "y" : 1257
          },
          "b" : {
            "x" : 4716,
            "y" : 1269
          },
          "type" : "BOX",
          "empty" : true,
          "centre" : {
            "x" : 4710,
            "y" : 1263
          }
        }
      },
      "endShape" : {
        "a" : {
          "x" : 4698,
          "y" : 1248
        },
        "b" : {
          "x" : 4690,
          "y" : 1247
        },
        "c" : {
          "x" : 4693,
          "y" : 1254
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 4693,
          "y" : 1254
        }
      }
    } ]
  }, {
    "id" : 108618,
    "reactomeId" : 74113,
    "displayName" : "Na+",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 4888,
      "y" : 1240
    },
    "minX" : 4822,
    "maxX" : 4910,
    "minY" : 1224,
    "maxY" : 1280,
    "prop" : {
      "x" : 4868,
      "y" : 1225,
      "width" : 41,
      "height" : 31
    },
    "textPosition" : {
      "x" : 4871,
      "y" : 1230
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 4904,
          "y" : 1230
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 4904,
          "y" : 1230
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 108616,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 4865,
          "y" : 1252
        },
        "to" : {
          "x" : 4822,
          "y" : 1280
        }
      } ],
      "stoichiometry" : {
        "value" : 2,
        "shape" : {
          "a" : {
            "x" : 4837,
            "y" : 1260
          },
          "b" : {
            "x" : 4849,
            "y" : 1272
          },
          "type" : "BOX",
          "empty" : true,
          "centre" : {
            "x" : 4843,
            "y" : 1266
          }
        }
      }
    } ]
  }, {
    "id" : 108621,
    "reactomeId" : 10926986,
    "displayName" : "SLC10A1",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 4770,
      "y" : 1228
    },
    "minX" : 4740,
    "maxX" : 4807,
    "minY" : 1211,
    "maxY" : 1272,
    "prop" : {
      "x" : 4740,
      "y" : 1217,
      "width" : 61,
      "height" : 23
    },
    "textPosition" : {
      "x" : 4743,
      "y" : 1211
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 4801,
          "y" : 1217
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 4801,
          "y" : 1217
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 108616,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 4769,
          "y" : 1243
        },
        "to" : {
          "x" : 4769,
          "y" : 1264
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 4769,
          "y" : 1268
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 4769,
          "y" : 1268
        }
      }
    } ]
  }, {
    "id" : 108620,
    "reactomeId" : 194156,
    "displayName" : "bile salts and acids",
    "schemaClass" : "DefinedSet",
    "renderableClass" : "EntitySet",
    "position" : {
      "x" : 4675,
      "y" : 1323
    },
    "minX" : 4635,
    "maxX" : 4731,
    "minY" : 1279,
    "maxY" : 1340,
    "prop" : {
      "x" : 4635,
      "y" : 1306,
      "width" : 80,
      "height" : 34
    },
    "textPosition" : {
      "x" : 4640,
      "y" : 1306
    },
    "connectors" : [ {
      "edgeId" : 108616,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 4696,
          "y" : 1300
        },
        "to" : {
          "x" : 4731,
          "y" : 1279
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 4700,
          "y" : 1293
        },
        "b" : {
          "x" : 4696,
          "y" : 1300
        },
        "c" : {
          "x" : 4704,
          "y" : 1300
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 4704,
          "y" : 1300
        }
      }
    }, {
      "edgeId" : 108622,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 108623,
    "reactomeId" : 10926991,
    "displayName" : "SLCO1A2",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 4772,
      "y" : 1366
    },
    "minX" : 4741,
    "maxX" : 4809,
    "minY" : 1328,
    "maxY" : 1378,
    "prop" : {
      "x" : 4741,
      "y" : 1355,
      "width" : 62,
      "height" : 23
    },
    "textPosition" : {
      "x" : 4744,
      "y" : 1349
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 4803,
          "y" : 1355
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 4803,
          "y" : 1355
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 108622,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 4771,
          "y" : 1352
        },
        "to" : {
          "x" : 4771,
          "y" : 1336
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 4771,
          "y" : 1332
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 4771,
          "y" : 1332
        }
      }
    } ]
  }, {
    "id" : 108625,
    "reactomeId" : 194117,
    "displayName" : "GCCA, TCCA",
    "schemaClass" : "DefinedSet",
    "renderableClass" : "EntitySet",
    "position" : {
      "x" : 4866,
      "y" : 1550
    },
    "minX" : 4825,
    "maxX" : 4907,
    "minY" : 1539,
    "maxY" : 1562,
    "prop" : {
      "x" : 4825,
      "y" : 1539,
      "width" : 82,
      "height" : 23
    },
    "textPosition" : {
      "x" : 4826,
      "y" : 1540
    },
    "connectors" : [ {
      "edgeId" : 108624,
      "type" : "INPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 108628,
      "type" : "INPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 108627,
    "reactomeId" : 10926978,
    "displayName" : "SLCO1B1",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 4770,
      "y" : 1634
    },
    "minX" : 4740,
    "maxX" : 4807,
    "minY" : 1603,
    "maxY" : 1646,
    "prop" : {
      "x" : 4740,
      "y" : 1623,
      "width" : 61,
      "height" : 23
    },
    "textPosition" : {
      "x" : 4743,
      "y" : 1617
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 4801,
          "y" : 1623
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 4801,
          "y" : 1623
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 108624,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 4770,
          "y" : 1620
        },
        "to" : {
          "x" : 4770,
          "y" : 1611
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 4770,
          "y" : 1607
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 4770,
          "y" : 1607
        }
      }
    } ]
  }, {
    "id" : 108626,
    "reactomeId" : 194097,
    "displayName" : "GCCA, TCCA",
    "schemaClass" : "DefinedSet",
    "renderableClass" : "EntitySet",
    "position" : {
      "x" : 4679,
      "y" : 1545
    },
    "minX" : 4638,
    "maxX" : 4720,
    "minY" : 1534,
    "maxY" : 1557,
    "prop" : {
      "x" : 4638,
      "y" : 1534,
      "width" : 82,
      "height" : 23
    },
    "textPosition" : {
      "x" : 4639,
      "y" : 1535
    },
    "connectors" : [ {
      "edgeId" : 108624,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 108628,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 108629,
    "reactomeId" : 10926973,
    "displayName" : "SLCO1B3",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 4770,
      "y" : 1468
    },
    "minX" : 4740,
    "maxX" : 4807,
    "minY" : 1451,
    "maxY" : 1509,
    "prop" : {
      "x" : 4740,
      "y" : 1457,
      "width" : 61,
      "height" : 23
    },
    "textPosition" : {
      "x" : 4743,
      "y" : 1451
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 4801,
          "y" : 1457
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 4801,
          "y" : 1457
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 108628,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 4770,
          "y" : 1483
        },
        "to" : {
          "x" : 4771,
          "y" : 1501
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 4771,
          "y" : 1505
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 4771,
          "y" : 1505
        }
      }
    } ]
  }, {
    "id" : 108631,
    "reactomeId" : 113592,
    "displayName" : "ATP",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 4495,
      "y" : 1503
    },
    "minX" : 4475,
    "maxX" : 4531,
    "minY" : 1487,
    "maxY" : 1519,
    "prop" : {
      "x" : 4475,
      "y" : 1488,
      "width" : 40,
      "height" : 31
    },
    "textPosition" : {
      "x" : 4479,
      "y" : 1493
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 4510,
          "y" : 1493
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 4510,
          "y" : 1493
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 108630,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 4518,
          "y" : 1496
        },
        "to" : {
          "x" : 4531,
          "y" : 1491
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 108633,
    "reactomeId" : 76194,
    "displayName" : "CoA-SH",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 4579,
      "y" : 1508
    },
    "minX" : 4531,
    "maxX" : 4610,
    "minY" : 1491,
    "maxY" : 1524,
    "prop" : {
      "x" : 4550,
      "y" : 1493,
      "width" : 59,
      "height" : 31
    },
    "textPosition" : {
      "x" : 4553,
      "y" : 1498
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 4604,
          "y" : 1498
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 4604,
          "y" : 1498
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 108630,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 4547,
          "y" : 1497
        },
        "to" : {
          "x" : 4531,
          "y" : 1491
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 108632,
    "reactomeId" : 194096,
    "displayName" : "CCA,CDCA",
    "schemaClass" : "DefinedSet",
    "renderableClass" : "EntitySet",
    "position" : {
      "x" : 4533,
      "y" : 1562
    },
    "minX" : 4498,
    "maxX" : 4568,
    "minY" : 1491,
    "maxY" : 1574,
    "prop" : {
      "x" : 4498,
      "y" : 1551,
      "width" : 70,
      "height" : 23
    },
    "textPosition" : {
      "x" : 4498,
      "y" : 1552
    },
    "connectors" : [ {
      "edgeId" : 108630,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 4532,
          "y" : 1545
        },
        "to" : {
          "x" : 4531,
          "y" : 1491
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 108635,
    "reactomeId" : 194073,
    "displayName" : "choloyl-CoA; chenodeoxycholoyl-CoA",
    "schemaClass" : "DefinedSet",
    "renderableClass" : "EntitySet",
    "position" : {
      "x" : 4531,
      "y" : 1359
    },
    "minX" : 4471,
    "maxX" : 4592,
    "minY" : 1301,
    "maxY" : 1435,
    "prop" : {
      "x" : 4471,
      "y" : 1334,
      "width" : 121,
      "height" : 51
    },
    "textPosition" : {
      "x" : 4473,
      "y" : 1335
    },
    "connectors" : [ {
      "edgeId" : 108630,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 4531,
          "y" : 1391
        },
        "to" : {
          "x" : 4531,
          "y" : 1435
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 4535,
          "y" : 1398
        },
        "b" : {
          "x" : 4531,
          "y" : 1391
        },
        "c" : {
          "x" : 4527,
          "y" : 1398
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 4527,
          "y" : 1398
        }
      }
    }, {
      "edgeId" : 108639,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 4530,
          "y" : 1328
        },
        "to" : {
          "x" : 4530,
          "y" : 1301
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 108634,
    "reactomeId" : 29356,
    "displayName" : "H2O",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 4588,
      "y" : 1453
    },
    "minX" : 4531,
    "maxX" : 4611,
    "minY" : 1435,
    "maxY" : 1469,
    "prop" : {
      "x" : 4567,
      "y" : 1438,
      "width" : 43,
      "height" : 31
    },
    "textPosition" : {
      "x" : 4571,
      "y" : 1443
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 4605,
          "y" : 1443
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 4605,
          "y" : 1443
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 108630,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 4564,
          "y" : 1446
        },
        "to" : {
          "x" : 4531,
          "y" : 1435
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 4556,
          "y" : 1448
        },
        "b" : {
          "x" : 4564,
          "y" : 1446
        },
        "c" : {
          "x" : 4559,
          "y" : 1440
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 4559,
          "y" : 1440
        }
      }
    } ],
    "trivial" : true
  }, {
    "id" : 108637,
    "reactomeId" : 111294,
    "displayName" : "PPi",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 4478,
      "y" : 1417
    },
    "minX" : 4461,
    "maxX" : 4531,
    "minY" : 1401,
    "maxY" : 1435,
    "prop" : {
      "x" : 4461,
      "y" : 1402,
      "width" : 34,
      "height" : 31
    },
    "textPosition" : {
      "x" : 4464,
      "y" : 1407
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 4490,
          "y" : 1407
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 4490,
          "y" : 1407
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 108630,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 4498,
          "y" : 1422
        },
        "to" : {
          "x" : 4531,
          "y" : 1435
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 4506,
          "y" : 1421
        },
        "b" : {
          "x" : 4498,
          "y" : 1422
        },
        "c" : {
          "x" : 4503,
          "y" : 1428
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 4503,
          "y" : 1428
        }
      }
    } ]
  }, {
    "id" : 108636,
    "reactomeId" : 76577,
    "displayName" : "AMP",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 4582,
      "y" : 1410
    },
    "minX" : 4531,
    "maxX" : 4604,
    "minY" : 1394,
    "maxY" : 1435,
    "prop" : {
      "x" : 4561,
      "y" : 1395,
      "width" : 42,
      "height" : 31
    },
    "textPosition" : {
      "x" : 4565,
      "y" : 1400
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 4598,
          "y" : 1400
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 4598,
          "y" : 1400
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 108630,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 4558,
          "y" : 1420
        },
        "to" : {
          "x" : 4531,
          "y" : 1435
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 4554,
          "y" : 1427
        },
        "b" : {
          "x" : 4558,
          "y" : 1420
        },
        "c" : {
          "x" : 4550,
          "y" : 1420
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 4550,
          "y" : 1420
        }
      }
    } ]
  }, {
    "id" : 108638,
    "reactomeId" : 10922675,
    "displayName" : "Homologues of SLC27A5",
    "schemaClass" : "DefinedSet",
    "renderableClass" : "EntitySet",
    "position" : {
      "x" : 4406,
      "y" : 1470
    },
    "minX" : 4376,
    "maxX" : 4523,
    "minY" : 1459,
    "maxY" : 1482,
    "prop" : {
      "x" : 4376,
      "y" : 1459,
      "width" : 61,
      "height" : 23
    },
    "textPosition" : {
      "x" : 4377,
      "y" : 1439
    },
    "connectors" : [ {
      "edgeId" : 108630,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 4440,
          "y" : 1470
        },
        "to" : {
          "x" : 4515,
          "y" : 1470
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 4519,
          "y" : 1470
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 4519,
          "y" : 1470
        }
      }
    } ]
  }, {
    "id" : 108641,
    "reactomeId" : 76194,
    "displayName" : "CoA-SH",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 4599,
      "y" : 1225
    },
    "minX" : 4530,
    "maxX" : 4630,
    "minY" : 1209,
    "maxY" : 1241,
    "prop" : {
      "x" : 4570,
      "y" : 1210,
      "width" : 59,
      "height" : 31
    },
    "textPosition" : {
      "x" : 4573,
      "y" : 1215
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 4624,
          "y" : 1215
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 4624,
          "y" : 1215
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 108639,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 4567,
          "y" : 1223
        },
        "to" : {
          "x" : 4530,
          "y" : 1221
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 4560,
          "y" : 1227
        },
        "b" : {
          "x" : 4567,
          "y" : 1223
        },
        "c" : {
          "x" : 4560,
          "y" : 1219
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 4560,
          "y" : 1219
        }
      }
    } ]
  }, {
    "id" : 108640,
    "reactomeId" : 194069,
    "displayName" : "Gly, TAU",
    "schemaClass" : "DefinedSet",
    "renderableClass" : "EntitySet",
    "position" : {
      "x" : 4580,
      "y" : 1309
    },
    "minX" : 4530,
    "maxX" : 4610,
    "minY" : 1298,
    "maxY" : 1321,
    "prop" : {
      "x" : 4551,
      "y" : 1298,
      "width" : 59,
      "height" : 23
    },
    "textPosition" : {
      "x" : 4551,
      "y" : 1299
    },
    "connectors" : [ {
      "edgeId" : 108639,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 4545,
          "y" : 1304
        },
        "to" : {
          "x" : 4530,
          "y" : 1301
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 108643,
    "reactomeId" : 10922700,
    "displayName" : "Homologues of BAAT",
    "schemaClass" : "DefinedSet",
    "renderableClass" : "EntitySet",
    "position" : {
      "x" : 4477,
      "y" : 1261
    },
    "minX" : 4457,
    "maxX" : 4522,
    "minY" : 1250,
    "maxY" : 1273,
    "prop" : {
      "x" : 4457,
      "y" : 1250,
      "width" : 40,
      "height" : 23
    },
    "textPosition" : {
      "x" : 4457,
      "y" : 1223
    },
    "connectors" : [ {
      "edgeId" : 108639,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 4500,
          "y" : 1261
        },
        "to" : {
          "x" : 4514,
          "y" : 1261
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 4518,
          "y" : 1262
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 4518,
          "y" : 1262
        }
      }
    } ]
  }, {
    "id" : 108642,
    "reactomeId" : 193416,
    "displayName" : "bile salts",
    "schemaClass" : "DefinedSet",
    "renderableClass" : "EntitySet",
    "position" : {
      "x" : 4692,
      "y" : 976
    },
    "minX" : 4530,
    "maxX" : 4722,
    "minY" : 965,
    "maxY" : 1221,
    "prop" : {
      "x" : 4662,
      "y" : 965,
      "width" : 60,
      "height" : 23
    },
    "textPosition" : {
      "x" : 4673,
      "y" : 959
    },
    "connectors" : [ {
      "edgeId" : 108639,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 4689,
          "y" : 994
        },
        "to" : {
          "x" : 4645,
          "y" : 1181
        }
      }, {
        "from" : {
          "x" : 4645,
          "y" : 1181
        },
        "to" : {
          "x" : 4530,
          "y" : 1221
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 4691,
          "y" : 1002
        },
        "b" : {
          "x" : 4689,
          "y" : 994
        },
        "c" : {
          "x" : 4684,
          "y" : 1000
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 4684,
          "y" : 1000
        }
      }
    } ]
  }, {
    "id" : 108645,
    "reactomeId" : 10933470,
    "displayName" : "unc-55",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 5414,
      "y" : 1016
    },
    "minX" : 5389,
    "maxX" : 5482,
    "minY" : 999,
    "maxY" : 1043,
    "prop" : {
      "x" : 5389,
      "y" : 1005,
      "width" : 51,
      "height" : 23
    },
    "textPosition" : {
      "x" : 5389,
      "y" : 1006
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 5440,
          "y" : 1005
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 5440,
          "y" : 1005
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 108644,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 5443,
          "y" : 1026
        },
        "to" : {
          "x" : 5479,
          "y" : 1043
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 108644,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 5443,
          "y" : 1013
        },
        "to" : {
          "x" : 5476,
          "y" : 1009
        }
      }, {
        "from" : {
          "x" : 5476,
          "y" : 1009
        },
        "to" : {
          "x" : 5478,
          "y" : 1026
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 5478,
          "y" : 1030
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 5478,
          "y" : 1030
        }
      }
    } ]
  }, {
    "id" : 108647,
    "reactomeId" : 10964908,
    "displayName" : "NR1H4:DCA,CDCA,LCHA",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 5590,
      "y" : 1042
    },
    "minX" : 5530,
    "maxX" : 5657,
    "minY" : 1018,
    "maxY" : 1061,
    "prop" : {
      "x" : 5530,
      "y" : 1024,
      "width" : 121,
      "height" : 37
    },
    "textPosition" : {
      "x" : 5530,
      "y" : 1026
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 5651,
          "y" : 1024
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 5651,
          "y" : 1024
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 108644,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 108646,
    "reactomeId" : 5340249,
    "displayName" : "DCA,CDCA,LCHA",
    "schemaClass" : "DefinedSet",
    "renderableClass" : "EntitySet",
    "position" : {
      "x" : 5433,
      "y" : 1087
    },
    "minX" : 5380,
    "maxX" : 5486,
    "minY" : 1043,
    "maxY" : 1099,
    "prop" : {
      "x" : 5380,
      "y" : 1076,
      "width" : 106,
      "height" : 23
    },
    "textPosition" : {
      "x" : 5380,
      "y" : 1077
    },
    "connectors" : [ {
      "edgeId" : 108644,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 5445,
          "y" : 1070
        },
        "to" : {
          "x" : 5479,
          "y" : 1043
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 108649,
    "reactomeId" : 10982542,
    "displayName" : "STARD5",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 4150,
      "y" : 1625
    },
    "minX" : 4122,
    "maxX" : 4263,
    "minY" : 1608,
    "maxY" : 1655,
    "prop" : {
      "x" : 4122,
      "y" : 1614,
      "width" : 56,
      "height" : 23
    },
    "textPosition" : {
      "x" : 4122,
      "y" : 1615
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 4178,
          "y" : 1614
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 4178,
          "y" : 1614
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 108648,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 4181,
          "y" : 1625
        },
        "to" : {
          "x" : 4220,
          "y" : 1625
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 108648,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 4181,
          "y" : 1632
        },
        "to" : {
          "x" : 4258,
          "y" : 1655
        }
      }, {
        "from" : {
          "x" : 4258,
          "y" : 1655
        },
        "to" : {
          "x" : 4258,
          "y" : 1641
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 4259,
          "y" : 1637
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 4259,
          "y" : 1637
        }
      }
    } ]
  }, {
    "id" : 108651,
    "reactomeId" : 10982544,
    "displayName" : "STARD5:DCA/LCA",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 4347,
      "y" : 1623
    },
    "minX" : 4312,
    "maxX" : 4389,
    "minY" : 1598,
    "maxY" : 1642,
    "prop" : {
      "x" : 4312,
      "y" : 1604,
      "width" : 71,
      "height" : 38
    },
    "textPosition" : {
      "x" : 4317,
      "y" : 1607
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 4383,
          "y" : 1604
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 4383,
          "y" : 1604
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 108648,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 108650,
    "reactomeId" : 8873845,
    "displayName" : "DCA, LCA",
    "schemaClass" : "DefinedSet",
    "renderableClass" : "EntitySet",
    "position" : {
      "x" : 4154,
      "y" : 1590
    },
    "minX" : 4122,
    "maxX" : 4220,
    "minY" : 1579,
    "maxY" : 1625,
    "prop" : {
      "x" : 4122,
      "y" : 1579,
      "width" : 64,
      "height" : 23
    },
    "textPosition" : {
      "x" : 4122,
      "y" : 1580
    },
    "connectors" : [ {
      "edgeId" : 108648,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 4175,
          "y" : 1608
        },
        "to" : {
          "x" : 4220,
          "y" : 1625
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 108653,
    "reactomeId" : 8868399,
    "displayName" : "25OH-CHOL",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 246,
      "y" : 981
    },
    "minX" : 203,
    "maxX" : 291,
    "minY" : 965,
    "maxY" : 1102,
    "prop" : {
      "x" : 203,
      "y" : 966,
      "width" : 87,
      "height" : 31
    },
    "textPosition" : {
      "x" : 207,
      "y" : 971
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 285,
          "y" : 971
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 285,
          "y" : 971
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 108652,
      "type" : "INPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 108656,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 246,
          "y" : 1000
        },
        "to" : {
          "x" : 246,
          "y" : 1102
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 108655,
    "reactomeId" : 10981721,
    "displayName" : "OSBPs",
    "schemaClass" : "DefinedSet",
    "renderableClass" : "EntitySet",
    "position" : {
      "x" : 320,
      "y" : 1024
    },
    "minX" : 298,
    "maxX" : 342,
    "minY" : 989,
    "maxY" : 1036,
    "prop" : {
      "x" : 298,
      "y" : 1013,
      "width" : 44,
      "height" : 23
    },
    "textPosition" : {
      "x" : 299,
      "y" : 1007
    },
    "connectors" : [ {
      "edgeId" : 108652,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 320,
          "y" : 1007
        },
        "to" : {
          "x" : 320,
          "y" : 997
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 321,
          "y" : 993
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 321,
          "y" : 993
        }
      }
    } ]
  }, {
    "id" : 108654,
    "reactomeId" : 8868400,
    "displayName" : "25OH-CHOL",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 410,
      "y" : 982
    },
    "minX" : 367,
    "maxX" : 455,
    "minY" : 966,
    "maxY" : 998,
    "prop" : {
      "x" : 367,
      "y" : 967,
      "width" : 87,
      "height" : 31
    },
    "textPosition" : {
      "x" : 371,
      "y" : 972
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 449,
          "y" : 972
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 449,
          "y" : 972
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 108652,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 108657,
    "reactomeId" : 1806217,
    "displayName" : "PI4P",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 169,
      "y" : 1126
    },
    "minX" : 148,
    "maxX" : 246,
    "minY" : 1102,
    "maxY" : 1142,
    "prop" : {
      "x" : 148,
      "y" : 1111,
      "width" : 42,
      "height" : 31
    },
    "textPosition" : {
      "x" : 151,
      "y" : 1116
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 185,
          "y" : 1116
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 185,
          "y" : 1116
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 108656,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 193,
          "y" : 1119
        },
        "to" : {
          "x" : 246,
          "y" : 1102
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 108659,
    "reactomeId" : 1806234,
    "displayName" : "PI4P",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 174,
      "y" : 1057
    },
    "minX" : 153,
    "maxX" : 246,
    "minY" : 1041,
    "maxY" : 1099,
    "prop" : {
      "x" : 153,
      "y" : 1042,
      "width" : 42,
      "height" : 31
    },
    "textPosition" : {
      "x" : 156,
      "y" : 1047
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 190,
          "y" : 1047
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 190,
          "y" : 1047
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 108656,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 198,
          "y" : 1069
        },
        "to" : {
          "x" : 246,
          "y" : 1099
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 206,
          "y" : 1069
        },
        "b" : {
          "x" : 198,
          "y" : 1069
        },
        "c" : {
          "x" : 202,
          "y" : 1076
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 202,
          "y" : 1076
        }
      }
    } ]
  }, {
    "id" : 108658,
    "reactomeId" : 8868393,
    "displayName" : "25OH-CHOL",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 247,
      "y" : 1153
    },
    "minX" : 204,
    "maxX" : 292,
    "minY" : 1099,
    "maxY" : 1169,
    "prop" : {
      "x" : 204,
      "y" : 1138,
      "width" : 87,
      "height" : 31
    },
    "textPosition" : {
      "x" : 208,
      "y" : 1143
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 286,
          "y" : 1143
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 286,
          "y" : 1143
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 108656,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 246,
          "y" : 1135
        },
        "to" : {
          "x" : 246,
          "y" : 1099
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 242,
          "y" : 1128
        },
        "b" : {
          "x" : 246,
          "y" : 1135
        },
        "c" : {
          "x" : 250,
          "y" : 1128
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 250,
          "y" : 1128
        }
      }
    } ]
  }, {
    "id" : 108660,
    "reactomeId" : 10981842,
    "displayName" : "obr-1",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 309,
      "y" : 1101
    },
    "minX" : 254,
    "maxX" : 334,
    "minY" : 1084,
    "maxY" : 1113,
    "prop" : {
      "x" : 290,
      "y" : 1090,
      "width" : 38,
      "height" : 23
    },
    "textPosition" : {
      "x" : 292,
      "y" : 1084
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 328,
          "y" : 1090
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 328,
          "y" : 1090
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 108656,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 287,
          "y" : 1100
        },
        "to" : {
          "x" : 262,
          "y" : 1100
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 258,
          "y" : 1100
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 258,
          "y" : 1100
        }
      }
    } ]
  }, {
    "id" : 108663,
    "reactomeId" : 10988955,
    "displayName" : "bile salts and acids:FABP6",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 5104,
      "y" : 1050
    },
    "minX" : 5058,
    "maxX" : 5156,
    "minY" : 1025,
    "maxY" : 1070,
    "prop" : {
      "x" : 5058,
      "y" : 1031,
      "width" : 92,
      "height" : 39
    },
    "textPosition" : {
      "x" : 5056,
      "y" : 1035
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 5150,
          "y" : 1031
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 5150,
          "y" : 1031
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 108661,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 108664,
      "type" : "INPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 108662,
    "reactomeId" : 10964809,
    "displayName" : "Homologues of FABP6",
    "schemaClass" : "DefinedSet",
    "renderableClass" : "EntitySet",
    "position" : {
      "x" : 5005,
      "y" : 1051
    },
    "minX" : 4983,
    "maxX" : 5107,
    "minY" : 989,
    "maxY" : 1118,
    "prop" : {
      "x" : 4983,
      "y" : 1040,
      "width" : 45,
      "height" : 23
    },
    "textPosition" : {
      "x" : 4983,
      "y" : 1013
    },
    "connectors" : [ {
      "edgeId" : 108661,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 5021,
          "y" : 1066
        },
        "to" : {
          "x" : 5104,
          "y" : 1118
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 108664,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 5023,
          "y" : 1037
        },
        "to" : {
          "x" : 5107,
          "y" : 989
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 5027,
          "y" : 1030
        },
        "b" : {
          "x" : 5023,
          "y" : 1037
        },
        "c" : {
          "x" : 5031,
          "y" : 1037
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 5031,
          "y" : 1037
        }
      }
    } ]
  }, {
    "id" : 108667,
    "reactomeId" : 29370,
    "displayName" : "ADP",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 5286,
      "y" : 1175
    },
    "minX" : 5239,
    "maxX" : 5308,
    "minY" : 1159,
    "maxY" : 1220,
    "prop" : {
      "x" : 5266,
      "y" : 1160,
      "width" : 41,
      "height" : 31
    },
    "textPosition" : {
      "x" : 5270,
      "y" : 1165
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 5302,
          "y" : 1165
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 5302,
          "y" : 1165
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 108665,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 5269,
          "y" : 1194
        },
        "to" : {
          "x" : 5239,
          "y" : 1220
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 5266,
          "y" : 1202
        },
        "b" : {
          "x" : 5269,
          "y" : 1194
        },
        "c" : {
          "x" : 5261,
          "y" : 1196
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 5261,
          "y" : 1196
        }
      }
    } ]
  }, {
    "id" : 108666,
    "reactomeId" : 113592,
    "displayName" : "ATP",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 5289,
      "y" : 1103
    },
    "minX" : 5236,
    "maxX" : 5310,
    "minY" : 1087,
    "maxY" : 1133,
    "prop" : {
      "x" : 5269,
      "y" : 1088,
      "width" : 40,
      "height" : 31
    },
    "textPosition" : {
      "x" : 5273,
      "y" : 1093
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 5304,
          "y" : 1093
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 5304,
          "y" : 1093
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 108665,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 5266,
          "y" : 1114
        },
        "to" : {
          "x" : 5236,
          "y" : 1133
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 108669,
    "reactomeId" : 10926999,
    "displayName" : "mrp-1",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 5331,
      "y" : 1220
    },
    "minX" : 5244,
    "maxX" : 5361,
    "minY" : 1203,
    "maxY" : 1232,
    "prop" : {
      "x" : 5307,
      "y" : 1209,
      "width" : 48,
      "height" : 23
    },
    "textPosition" : {
      "x" : 5309,
      "y" : 1210
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 5355,
          "y" : 1209
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 5355,
          "y" : 1209
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 108665,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 5304,
          "y" : 1220
        },
        "to" : {
          "x" : 5252,
          "y" : 1220
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 5248,
          "y" : 1220
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 5248,
          "y" : 1220
        }
      }
    } ]
  }, {
    "id" : 108668,
    "reactomeId" : 29372,
    "displayName" : "Pi",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 5336,
      "y" : 1177
    },
    "minX" : 5239,
    "maxX" : 5351,
    "minY" : 1161,
    "maxY" : 1220,
    "prop" : {
      "x" : 5323,
      "y" : 1162,
      "width" : 27,
      "height" : 31
    },
    "textPosition" : {
      "x" : 5327,
      "y" : 1167
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 5345,
          "y" : 1167
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 5345,
          "y" : 1167
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 108665,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 5320,
          "y" : 1182
        },
        "to" : {
          "x" : 5239,
          "y" : 1220
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 5315,
          "y" : 1189
        },
        "b" : {
          "x" : 5320,
          "y" : 1182
        },
        "c" : {
          "x" : 5312,
          "y" : 1181
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 5312,
          "y" : 1181
        }
      }
    } ]
  }, {
    "id" : 108714,
    "reactomeId" : 193473,
    "displayName" : "CCA",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 4460,
      "y" : 1225
    },
    "minX" : 4440,
    "maxX" : 4482,
    "minY" : 1209,
    "maxY" : 1241,
    "prop" : {
      "x" : 4440,
      "y" : 1210,
      "width" : 41,
      "height" : 31
    },
    "textPosition" : {
      "x" : 4444,
      "y" : 1215
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 4476,
          "y" : 1215
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 4476,
          "y" : 1215
        }
      }
    },
    "connectors" : [ ]
  }, {
    "id" : 108475,
    "reactomeId" : 70106,
    "displayName" : "H+",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 912,
      "y" : 973
    },
    "minX" : 895,
    "maxX" : 935,
    "minY" : 915,
    "maxY" : 1037,
    "prop" : {
      "x" : 895,
      "y" : 958,
      "width" : 34,
      "height" : 31
    },
    "textPosition" : {
      "x" : 898,
      "y" : 963
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 924,
          "y" : 963
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 924,
          "y" : 963
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 108480,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 917,
          "y" : 955
        },
        "to" : {
          "x" : 931,
          "y" : 915
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 108473,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 917,
          "y" : 992
        },
        "to" : {
          "x" : 935,
          "y" : 1037
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ],
    "trivial" : true
  }, {
    "id" : 108474,
    "reactomeId" : 192195,
    "displayName" : "4CHOL7a,12aDONE",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 696,
      "y" : 1076
    },
    "minX" : 630,
    "maxX" : 935,
    "minY" : 1037,
    "maxY" : 1092,
    "prop" : {
      "x" : 630,
      "y" : 1061,
      "width" : 133,
      "height" : 31
    },
    "textPosition" : {
      "x" : 633,
      "y" : 1066
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 758,
          "y" : 1066
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 758,
          "y" : 1066
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 108473,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 766,
          "y" : 1065
        },
        "to" : {
          "x" : 935,
          "y" : 1037
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 108477,
    "reactomeId" : 192064,
    "displayName" : "5beta-cholesten-7alpha, 12alpha-diol-3-one",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 1115,
      "y" : 1035
    },
    "minX" : 1001,
    "maxX" : 1206,
    "minY" : 1005,
    "maxY" : 1065,
    "prop" : {
      "x" : 1057,
      "y" : 1006,
      "width" : 117,
      "height" : 59
    },
    "textPosition" : {
      "x" : 1058,
      "y" : 1011
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1169,
          "y" : 1011
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1169,
          "y" : 1011
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 108483,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1177,
          "y" : 1035
        },
        "to" : {
          "x" : 1206,
          "y" : 1035
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 108473,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 1054,
          "y" : 1036
        },
        "to" : {
          "x" : 1001,
          "y" : 1038
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 1047,
          "y" : 1040
        },
        "b" : {
          "x" : 1054,
          "y" : 1036
        },
        "c" : {
          "x" : 1047,
          "y" : 1032
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 1047,
          "y" : 1032
        }
      }
    } ]
  }, {
    "id" : 108476,
    "reactomeId" : 29364,
    "displayName" : "NADPH",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 857,
      "y" : 973
    },
    "minX" : 828,
    "maxX" : 935,
    "minY" : 915,
    "maxY" : 1037,
    "prop" : {
      "x" : 828,
      "y" : 958,
      "width" : 59,
      "height" : 31
    },
    "textPosition" : {
      "x" : 832,
      "y" : 963
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 882,
          "y" : 963
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 882,
          "y" : 963
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 108480,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 876,
          "y" : 955
        },
        "to" : {
          "x" : 931,
          "y" : 915
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 108473,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 875,
          "y" : 992
        },
        "to" : {
          "x" : 935,
          "y" : 1037
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 108479,
    "reactomeId" : 10926717,
    "displayName" : "Homologues of AKR1D1",
    "schemaClass" : "DefinedSet",
    "renderableClass" : "EntitySet",
    "position" : {
      "x" : 981,
      "y" : 973
    },
    "minX" : 952,
    "maxX" : 1010,
    "minY" : 922,
    "maxY" : 1029,
    "prop" : {
      "x" : 952,
      "y" : 962,
      "width" : 58,
      "height" : 23
    },
    "textPosition" : {
      "x" : 952,
      "y" : 949
    },
    "connectors" : [ {
      "edgeId" : 108480,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 980,
          "y" : 959
        },
        "to" : {
          "x" : 980,
          "y" : 930
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 980,
          "y" : 926
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 980,
          "y" : 926
        }
      }
    }, {
      "edgeId" : 108473,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 981,
          "y" : 988
        },
        "to" : {
          "x" : 982,
          "y" : 1021
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 983,
          "y" : 1025
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 983,
          "y" : 1025
        }
      }
    } ]
  }, {
    "id" : 108478,
    "reactomeId" : 29366,
    "displayName" : "NADP+",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 1078,
      "y" : 971
    },
    "minX" : 1001,
    "maxX" : 1108,
    "minY" : 915,
    "maxY" : 1038,
    "prop" : {
      "x" : 1049,
      "y" : 956,
      "width" : 58,
      "height" : 31
    },
    "textPosition" : {
      "x" : 1052,
      "y" : 961
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1102,
          "y" : 961
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1102,
          "y" : 961
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 108480,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 1057,
          "y" : 953
        },
        "to" : {
          "x" : 1004,
          "y" : 915
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 1049,
          "y" : 952
        },
        "b" : {
          "x" : 1057,
          "y" : 953
        },
        "c" : {
          "x" : 1054,
          "y" : 946
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 1054,
          "y" : 946
        }
      }
    }, {
      "edgeId" : 108473,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 1060,
          "y" : 990
        },
        "to" : {
          "x" : 1001,
          "y" : 1038
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 1057,
          "y" : 997
        },
        "b" : {
          "x" : 1060,
          "y" : 990
        },
        "c" : {
          "x" : 1052,
          "y" : 991
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 1052,
          "y" : 991
        }
      }
    } ]
  }, {
    "id" : 108481,
    "reactomeId" : 192136,
    "displayName" : "4CHOL7aOLONE",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 676,
      "y" : 892
    },
    "minX" : 620,
    "maxX" : 931,
    "minY" : 876,
    "maxY" : 915,
    "prop" : {
      "x" : 620,
      "y" : 877,
      "width" : 112,
      "height" : 31
    },
    "textPosition" : {
      "x" : 623,
      "y" : 882
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 727,
          "y" : 882
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 727,
          "y" : 882
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 108480,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 735,
          "y" : 897
        },
        "to" : {
          "x" : 931,
          "y" : 915
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 108482,
    "reactomeId" : 191980,
    "displayName" : "5beta-cholestan-7alpha-ol-3-one",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 1101,
      "y" : 909
    },
    "minX" : 1004,
    "maxX" : 1196,
    "minY" : 886,
    "maxY" : 932,
    "prop" : {
      "x" : 1045,
      "y" : 887,
      "width" : 113,
      "height" : 45
    },
    "textPosition" : {
      "x" : 1048,
      "y" : 885
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1153,
          "y" : 892
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1153,
          "y" : 892
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 108480,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 1042,
          "y" : 912
        },
        "to" : {
          "x" : 1004,
          "y" : 915
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 1035,
          "y" : 917
        },
        "b" : {
          "x" : 1042,
          "y" : 912
        },
        "c" : {
          "x" : 1035,
          "y" : 909
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 1035,
          "y" : 909
        }
      }
    }, {
      "edgeId" : 108489,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1161,
          "y" : 911
        },
        "to" : {
          "x" : 1196,
          "y" : 914
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 108485,
    "reactomeId" : 29364,
    "displayName" : "NADPH",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 1140,
      "y" : 973
    },
    "minX" : 1111,
    "maxX" : 1206,
    "minY" : 914,
    "maxY" : 1035,
    "prop" : {
      "x" : 1111,
      "y" : 958,
      "width" : 59,
      "height" : 31
    },
    "textPosition" : {
      "x" : 1115,
      "y" : 963
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1165,
          "y" : 963
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1165,
          "y" : 963
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 108483,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1156,
          "y" : 992
        },
        "to" : {
          "x" : 1206,
          "y" : 1035
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 108489,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1154,
          "y" : 955
        },
        "to" : {
          "x" : 1196,
          "y" : 914
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 108484,
    "reactomeId" : 70106,
    "displayName" : "H+",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 1192,
      "y" : 974
    },
    "minX" : 1175,
    "maxX" : 1210,
    "minY" : 914,
    "maxY" : 1035,
    "prop" : {
      "x" : 1175,
      "y" : 959,
      "width" : 34,
      "height" : 31
    },
    "textPosition" : {
      "x" : 1178,
      "y" : 964
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1204,
          "y" : 964
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1204,
          "y" : 964
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 108483,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1195,
          "y" : 993
        },
        "to" : {
          "x" : 1206,
          "y" : 1035
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 108489,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1193,
          "y" : 956
        },
        "to" : {
          "x" : 1196,
          "y" : 914
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ],
    "trivial" : true
  }, {
    "id" : 108487,
    "reactomeId" : 29366,
    "displayName" : "NADP+",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 1349,
      "y" : 976
    },
    "minX" : 1297,
    "maxX" : 1379,
    "minY" : 914,
    "maxY" : 1034,
    "prop" : {
      "x" : 1320,
      "y" : 961,
      "width" : 58,
      "height" : 31
    },
    "textPosition" : {
      "x" : 1323,
      "y" : 966
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1373,
          "y" : 966
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1373,
          "y" : 966
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 108483,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 1335,
          "y" : 995
        },
        "to" : {
          "x" : 1297,
          "y" : 1034
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 1333,
          "y" : 1003
        },
        "b" : {
          "x" : 1335,
          "y" : 995
        },
        "c" : {
          "x" : 1327,
          "y" : 997
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 1327,
          "y" : 997
        }
      }
    }, {
      "edgeId" : 108489,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 1336,
          "y" : 958
        },
        "to" : {
          "x" : 1299,
          "y" : 914
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 1328,
          "y" : 955
        },
        "b" : {
          "x" : 1336,
          "y" : 958
        },
        "c" : {
          "x" : 1335,
          "y" : 950
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 1335,
          "y" : 950
        }
      }
    } ]
  }, {
    "id" : 108486,
    "reactomeId" : 192087,
    "displayName" : "5beta-cholestan-3alpha,7alpha,12alpha-triol",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 1369,
      "y" : 1077
    },
    "minX" : 1297,
    "maxX" : 1427,
    "minY" : 1034,
    "maxY" : 1107,
    "prop" : {
      "x" : 1313,
      "y" : 1048,
      "width" : 113,
      "height" : 59
    },
    "textPosition" : {
      "x" : 1318,
      "y" : 1046
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1421,
          "y" : 1053
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1421,
          "y" : 1053
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 108483,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 1319,
          "y" : 1045
        },
        "to" : {
          "x" : 1297,
          "y" : 1034
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 1311,
          "y" : 1045
        },
        "b" : {
          "x" : 1319,
          "y" : 1045
        },
        "c" : {
          "x" : 1315,
          "y" : 1038
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 1315,
          "y" : 1038
        }
      }
    } ]
  }, {
    "id" : 108488,
    "reactomeId" : 10926736,
    "displayName" : "Homologues of AKR1C4",
    "schemaClass" : "DefinedSet",
    "renderableClass" : "EntitySet",
    "position" : {
      "x" : 1258,
      "y" : 971
    },
    "minX" : 1221,
    "maxX" : 1296,
    "minY" : 922,
    "maxY" : 1026,
    "prop" : {
      "x" : 1221,
      "y" : 948,
      "width" : 75,
      "height" : 46
    },
    "textPosition" : {
      "x" : 1223,
      "y" : 947
    },
    "connectors" : [ {
      "edgeId" : 108483,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 1259,
          "y" : 1000
        },
        "to" : {
          "x" : 1260,
          "y" : 1018
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 1260,
          "y" : 1022
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1260,
          "y" : 1022
        }
      }
    }, {
      "edgeId" : 108489,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 1256,
          "y" : 942
        },
        "to" : {
          "x" : 1255,
          "y" : 930
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 1255,
          "y" : 926
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1255,
          "y" : 926
        }
      }
    } ]
  }, {
    "id" : 108490,
    "reactomeId" : 192030,
    "displayName" : "5beta-cholestan-3alpha,7alpha-diol",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 1357,
      "y" : 870
    },
    "minX" : 1294,
    "maxX" : 1421,
    "minY" : 847,
    "maxY" : 914,
    "prop" : {
      "x" : 1294,
      "y" : 848,
      "width" : 126,
      "height" : 45
    },
    "textPosition" : {
      "x" : 1295,
      "y" : 853
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1415,
          "y" : 853
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1415,
          "y" : 853
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 108489,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 1327,
          "y" : 896
        },
        "to" : {
          "x" : 1299,
          "y" : 914
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 1323,
          "y" : 903
        },
        "b" : {
          "x" : 1327,
          "y" : 896
        },
        "c" : {
          "x" : 1319,
          "y" : 896
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 1319,
          "y" : 896
        }
      }
    } ]
  }, {
    "id" : 108493,
    "reactomeId" : 113592,
    "displayName" : "ATP",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 2542,
      "y" : 983
    },
    "minX" : 2522,
    "maxX" : 2659,
    "minY" : 877,
    "maxY" : 1112,
    "prop" : {
      "x" : 2522,
      "y" : 968,
      "width" : 40,
      "height" : 31
    },
    "textPosition" : {
      "x" : 2526,
      "y" : 973
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 2557,
          "y" : 973
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 2557,
          "y" : 973
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 108491,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 2555,
          "y" : 1002
        },
        "to" : {
          "x" : 2652,
          "y" : 1112
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 108499,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 2556,
          "y" : 965
        },
        "to" : {
          "x" : 2638,
          "y" : 877
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 108502,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 2562,
          "y" : 965
        },
        "to" : {
          "x" : 2656,
          "y" : 897
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 108504,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 2560,
          "y" : 1002
        },
        "to" : {
          "x" : 2659,
          "y" : 1081
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 108492,
    "reactomeId" : 192013,
    "displayName" : "THCA",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 2550,
      "y" : 1040
    },
    "minX" : 2525,
    "maxX" : 2656,
    "minY" : 897,
    "maxY" : 1112,
    "prop" : {
      "x" : 2525,
      "y" : 1025,
      "width" : 50,
      "height" : 31
    },
    "textPosition" : {
      "x" : 2530,
      "y" : 1030
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 2570,
          "y" : 1030
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 2570,
          "y" : 1030
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 108491,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 2571,
          "y" : 1059
        },
        "to" : {
          "x" : 2652,
          "y" : 1112
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 108502,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 2561,
          "y" : 1022
        },
        "to" : {
          "x" : 2656,
          "y" : 897
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 108495,
    "reactomeId" : 192096,
    "displayName" : "25(R) THCA-CoA",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 2979,
      "y" : 1041
    },
    "minX" : 2791,
    "maxX" : 3037,
    "minY" : 895,
    "maxY" : 1110,
    "prop" : {
      "x" : 2923,
      "y" : 1026,
      "width" : 113,
      "height" : 31
    },
    "textPosition" : {
      "x" : 2926,
      "y" : 1031
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 3031,
          "y" : 1031
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 3031,
          "y" : 1031
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 108491,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 2936,
          "y" : 1060
        },
        "to" : {
          "x" : 2791,
          "y" : 1110
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 2931,
          "y" : 1066
        },
        "b" : {
          "x" : 2936,
          "y" : 1060
        },
        "c" : {
          "x" : 2928,
          "y" : 1058
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 2928,
          "y" : 1058
        }
      }
    }, {
      "edgeId" : 108502,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 2959,
          "y" : 1023
        },
        "to" : {
          "x" : 2793,
          "y" : 895
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 2951,
          "y" : 1022
        },
        "b" : {
          "x" : 2959,
          "y" : 1023
        },
        "c" : {
          "x" : 2956,
          "y" : 1016
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 2956,
          "y" : 1016
        }
      }
    } ]
  }, {
    "id" : 108494,
    "reactomeId" : 76194,
    "displayName" : "CoA-SH",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 2633,
      "y" : 986
    },
    "minX" : 2604,
    "maxX" : 2664,
    "minY" : 877,
    "maxY" : 1112,
    "prop" : {
      "x" : 2604,
      "y" : 971,
      "width" : 59,
      "height" : 31
    },
    "textPosition" : {
      "x" : 2607,
      "y" : 976
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 2658,
          "y" : 976
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 2658,
          "y" : 976
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 108491,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 2635,
          "y" : 1005
        },
        "to" : {
          "x" : 2652,
          "y" : 1112
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 108499,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 2633,
          "y" : 968
        },
        "to" : {
          "x" : 2638,
          "y" : 877
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 108502,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 2637,
          "y" : 968
        },
        "to" : {
          "x" : 2656,
          "y" : 897
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 108504,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 2637,
          "y" : 1005
        },
        "to" : {
          "x" : 2659,
          "y" : 1081
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 108497,
    "reactomeId" : 111294,
    "displayName" : "PPi",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 2982,
      "y" : 989
    },
    "minX" : 2791,
    "maxX" : 3000,
    "minY" : 876,
    "maxY" : 1110,
    "prop" : {
      "x" : 2965,
      "y" : 974,
      "width" : 34,
      "height" : 31
    },
    "textPosition" : {
      "x" : 2968,
      "y" : 979
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 2994,
          "y" : 979
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 2994,
          "y" : 979
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 108491,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 2962,
          "y" : 999
        },
        "to" : {
          "x" : 2791,
          "y" : 1110
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 2958,
          "y" : 1006
        },
        "b" : {
          "x" : 2962,
          "y" : 999
        },
        "c" : {
          "x" : 2954,
          "y" : 999
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 2954,
          "y" : 999
        }
      }
    }, {
      "edgeId" : 108499,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 2962,
          "y" : 978
        },
        "to" : {
          "x" : 2795,
          "y" : 876
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 2954,
          "y" : 978
        },
        "b" : {
          "x" : 2962,
          "y" : 978
        },
        "c" : {
          "x" : 2958,
          "y" : 971
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 2958,
          "y" : 971
        }
      }
    }, {
      "edgeId" : 108502,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 2962,
          "y" : 980
        },
        "to" : {
          "x" : 2793,
          "y" : 895
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 2954,
          "y" : 980
        },
        "b" : {
          "x" : 2962,
          "y" : 980
        },
        "c" : {
          "x" : 2958,
          "y" : 973
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 2958,
          "y" : 973
        }
      }
    }, {
      "edgeId" : 108504,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 2962,
          "y" : 997
        },
        "to" : {
          "x" : 2792,
          "y" : 1082
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 2958,
          "y" : 1004
        },
        "b" : {
          "x" : 2962,
          "y" : 997
        },
        "c" : {
          "x" : 2954,
          "y" : 997
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 2954,
          "y" : 997
        }
      }
    } ]
  }, {
    "id" : 108496,
    "reactomeId" : 76577,
    "displayName" : "AMP",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 2878,
      "y" : 987
    },
    "minX" : 2791,
    "maxX" : 2900,
    "minY" : 876,
    "maxY" : 1110,
    "prop" : {
      "x" : 2857,
      "y" : 972,
      "width" : 42,
      "height" : 31
    },
    "textPosition" : {
      "x" : 2861,
      "y" : 977
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 2894,
          "y" : 977
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 2894,
          "y" : 977
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 108491,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 2867,
          "y" : 1006
        },
        "to" : {
          "x" : 2791,
          "y" : 1110
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 2866,
          "y" : 1014
        },
        "b" : {
          "x" : 2867,
          "y" : 1006
        },
        "c" : {
          "x" : 2860,
          "y" : 1009
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 2860,
          "y" : 1009
        }
      }
    }, {
      "edgeId" : 108499,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 2866,
          "y" : 969
        },
        "to" : {
          "x" : 2795,
          "y" : 876
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 2859,
          "y" : 966
        },
        "b" : {
          "x" : 2866,
          "y" : 969
        },
        "c" : {
          "x" : 2865,
          "y" : 961
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 2865,
          "y" : 961
        }
      }
    }, {
      "edgeId" : 108502,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 2863,
          "y" : 969
        },
        "to" : {
          "x" : 2793,
          "y" : 895
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 2855,
          "y" : 967
        },
        "b" : {
          "x" : 2863,
          "y" : 969
        },
        "c" : {
          "x" : 2861,
          "y" : 961
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 2861,
          "y" : 961
        }
      }
    }, {
      "edgeId" : 108504,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 2863,
          "y" : 1006
        },
        "to" : {
          "x" : 2792,
          "y" : 1082
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 2861,
          "y" : 1014
        },
        "b" : {
          "x" : 2863,
          "y" : 1006
        },
        "c" : {
          "x" : 2855,
          "y" : 1008
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 2855,
          "y" : 1008
        }
      }
    } ]
  }, {
    "id" : 108498,
    "reactomeId" : 10926920,
    "displayName" : "Homologues of SLC27A2",
    "schemaClass" : "DefinedSet",
    "renderableClass" : "EntitySet",
    "position" : {
      "x" : 2704,
      "y" : 1031
    },
    "minX" : 2674,
    "maxX" : 2735,
    "minY" : 885,
    "maxY" : 1103,
    "prop" : {
      "x" : 2674,
      "y" : 1020,
      "width" : 61,
      "height" : 23
    },
    "textPosition" : {
      "x" : 2675,
      "y" : 1000
    },
    "connectors" : [ {
      "edgeId" : 108491,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 2704,
          "y" : 1046
        },
        "to" : {
          "x" : 2706,
          "y" : 1095
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 2706,
          "y" : 1099
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 2706,
          "y" : 1099
        }
      }
    }, {
      "edgeId" : 108499,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 2703,
          "y" : 1017
        },
        "to" : {
          "x" : 2700,
          "y" : 893
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 2700,
          "y" : 889
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 2700,
          "y" : 889
        }
      }
    } ]
  }, {
    "id" : 108501,
    "reactomeId" : 193457,
    "displayName" : "25(R) DHCA-CoA",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 2979,
      "y" : 936
    },
    "minX" : 2792,
    "maxX" : 3037,
    "minY" : 876,
    "maxY" : 1082,
    "prop" : {
      "x" : 2922,
      "y" : 921,
      "width" : 114,
      "height" : 31
    },
    "textPosition" : {
      "x" : 2925,
      "y" : 926
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 3031,
          "y" : 926
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 3031,
          "y" : 926
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 108499,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 2931,
          "y" : 918
        },
        "to" : {
          "x" : 2795,
          "y" : 876
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 2923,
          "y" : 920
        },
        "b" : {
          "x" : 2931,
          "y" : 918
        },
        "c" : {
          "x" : 2926,
          "y" : 912
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 2926,
          "y" : 912
        }
      }
    }, {
      "edgeId" : 108504,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 2959,
          "y" : 955
        },
        "to" : {
          "x" : 2792,
          "y" : 1082
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 2956,
          "y" : 962
        },
        "b" : {
          "x" : 2959,
          "y" : 955
        },
        "c" : {
          "x" : 2951,
          "y" : 956
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 2951,
          "y" : 956
        }
      }
    } ]
  }, {
    "id" : 108500,
    "reactomeId" : 193505,
    "displayName" : "DHCA",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 2549,
      "y" : 927
    },
    "minX" : 2524,
    "maxX" : 2659,
    "minY" : 877,
    "maxY" : 1081,
    "prop" : {
      "x" : 2524,
      "y" : 912,
      "width" : 51,
      "height" : 31
    },
    "textPosition" : {
      "x" : 2528,
      "y" : 917
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 2570,
          "y" : 917
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 2570,
          "y" : 917
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 108499,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 2578,
          "y" : 912
        },
        "to" : {
          "x" : 2638,
          "y" : 877
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 108504,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 2560,
          "y" : 946
        },
        "to" : {
          "x" : 2659,
          "y" : 1081
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 108503,
    "reactomeId" : 10922675,
    "displayName" : "Homologues of SLC27A5",
    "schemaClass" : "DefinedSet",
    "renderableClass" : "EntitySet",
    "position" : {
      "x" : 2808,
      "y" : 991
    },
    "minX" : 2756,
    "maxX" : 2839,
    "minY" : 902,
    "maxY" : 1075,
    "prop" : {
      "x" : 2778,
      "y" : 980,
      "width" : 61,
      "height" : 23
    },
    "textPosition" : {
      "x" : 2779,
      "y" : 960
    },
    "connectors" : [ {
      "edgeId" : 108502,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 2801,
          "y" : 977
        },
        "to" : {
          "x" : 2762,
          "y" : 910
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 2760,
          "y" : 906
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 2760,
          "y" : 906
        }
      }
    }, {
      "edgeId" : 108504,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 2802,
          "y" : 1006
        },
        "to" : {
          "x" : 2769,
          "y" : 1068
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 2767,
          "y" : 1071
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 2767,
          "y" : 1071
        }
      }
    } ]
  }, {
    "id" : 108507,
    "reactomeId" : 192316,
    "displayName" : "25(S) THCA-CoA",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 3302,
      "y" : 1080
    },
    "minX" : 3247,
    "maxX" : 3359,
    "minY" : 1043,
    "maxY" : 1096,
    "prop" : {
      "x" : 3247,
      "y" : 1065,
      "width" : 111,
      "height" : 31
    },
    "textPosition" : {
      "x" : 3249,
      "y" : 1070
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 3353,
          "y" : 1070
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 3353,
          "y" : 1070
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 108505,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 108512,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 3315,
          "y" : 1062
        },
        "to" : {
          "x" : 3335,
          "y" : 1043
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 108506,
    "reactomeId" : 192308,
    "displayName" : "25(R) THCA-CoA",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 3147,
      "y" : 1081
    },
    "minX" : 3091,
    "maxX" : 3205,
    "minY" : 1065,
    "maxY" : 1097,
    "prop" : {
      "x" : 3091,
      "y" : 1066,
      "width" : 113,
      "height" : 31
    },
    "textPosition" : {
      "x" : 3094,
      "y" : 1071
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 3199,
          "y" : 1071
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 3199,
          "y" : 1071
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 108505,
      "type" : "INPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 108508,
    "reactomeId" : 10926744,
    "displayName" : "AMACR",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 3214,
      "y" : 781
    },
    "minX" : 3189,
    "maxX" : 3251,
    "minY" : 468,
    "maxY" : 1031,
    "prop" : {
      "x" : 3189,
      "y" : 770,
      "width" : 51,
      "height" : 23
    },
    "textPosition" : {
      "x" : 3189,
      "y" : 771
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 3240,
          "y" : 770
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 3240,
          "y" : 770
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 108505,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 3213,
          "y" : 796
        },
        "to" : {
          "x" : 3213,
          "y" : 1023
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 3213,
          "y" : 1027
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 3213,
          "y" : 1027
        }
      }
    }, {
      "edgeId" : 108509,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 3212,
          "y" : 796
        },
        "to" : {
          "x" : 3197,
          "y" : 921
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 3196,
          "y" : 925
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 3196,
          "y" : 925
        }
      }
    }, {
      "edgeId" : 108579,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 3214,
          "y" : 767
        },
        "to" : {
          "x" : 3218,
          "y" : 476
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 3218,
          "y" : 472
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 3218,
          "y" : 472
        }
      }
    }, {
      "edgeId" : 108581,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 3217,
          "y" : 767
        },
        "to" : {
          "x" : 3246,
          "y" : 663
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 3247,
          "y" : 660
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 3247,
          "y" : 660
        }
      }
    } ]
  }, {
    "id" : 108511,
    "reactomeId" : 193442,
    "displayName" : "25(S) DHCA-CoA",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 3283,
      "y" : 941
    },
    "minX" : 3227,
    "maxX" : 3349,
    "minY" : 925,
    "maxY" : 957,
    "prop" : {
      "x" : 3227,
      "y" : 926,
      "width" : 112,
      "height" : 31
    },
    "textPosition" : {
      "x" : 3229,
      "y" : 931
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 3334,
          "y" : 931
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 3334,
          "y" : 931
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 108509,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 108517,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 3342,
          "y" : 941
        },
        "to" : {
          "x" : 3349,
          "y" : 941
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 108510,
    "reactomeId" : 193429,
    "displayName" : "25(R) DHCA-CoA",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 3136,
      "y" : 880
    },
    "minX" : 3079,
    "maxX" : 3194,
    "minY" : 864,
    "maxY" : 896,
    "prop" : {
      "x" : 3079,
      "y" : 865,
      "width" : 114,
      "height" : 31
    },
    "textPosition" : {
      "x" : 3082,
      "y" : 870
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 3188,
          "y" : 870
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 3188,
          "y" : 870
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 108509,
      "type" : "INPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 108513,
    "reactomeId" : 113535,
    "displayName" : "O2",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 3293,
      "y" : 988
    },
    "minX" : 3276,
    "maxX" : 3349,
    "minY" : 941,
    "maxY" : 1043,
    "prop" : {
      "x" : 3276,
      "y" : 973,
      "width" : 34,
      "height" : 31
    },
    "textPosition" : {
      "x" : 3280,
      "y" : 978
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 3305,
          "y" : 978
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 3305,
          "y" : 978
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 108512,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 3304,
          "y" : 1007
        },
        "to" : {
          "x" : 3335,
          "y" : 1043
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 108517,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 3313,
          "y" : 973
        },
        "to" : {
          "x" : 3349,
          "y" : 941
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ],
    "trivial" : true
  }, {
    "id" : 108515,
    "reactomeId" : 192342,
    "displayName" : "THCA-CoA",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 3541,
      "y" : 1045
    },
    "minX" : 3446,
    "maxX" : 3618,
    "minY" : 1029,
    "maxY" : 1061,
    "prop" : {
      "x" : 3503,
      "y" : 1030,
      "width" : 77,
      "height" : 31
    },
    "textPosition" : {
      "x" : 3507,
      "y" : 1035
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 3575,
          "y" : 1035
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 3575,
          "y" : 1035
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 108512,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 3500,
          "y" : 1044
        },
        "to" : {
          "x" : 3446,
          "y" : 1043
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 3493,
          "y" : 1048
        },
        "b" : {
          "x" : 3500,
          "y" : 1044
        },
        "c" : {
          "x" : 3493,
          "y" : 1040
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 3493,
          "y" : 1040
        }
      }
    }, {
      "edgeId" : 108519,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 3583,
          "y" : 1042
        },
        "to" : {
          "x" : 3618,
          "y" : 1040
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 108514,
    "reactomeId" : 113575,
    "displayName" : "H2O2",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 3480,
      "y" : 989
    },
    "minX" : 3444,
    "maxX" : 3507,
    "minY" : 942,
    "maxY" : 1043,
    "prop" : {
      "x" : 3455,
      "y" : 974,
      "width" : 51,
      "height" : 31
    },
    "textPosition" : {
      "x" : 3459,
      "y" : 979
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 3501,
          "y" : 979
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 3501,
          "y" : 979
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 108512,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 3470,
          "y" : 1008
        },
        "to" : {
          "x" : 3446,
          "y" : 1043
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 3469,
          "y" : 1016
        },
        "b" : {
          "x" : 3470,
          "y" : 1008
        },
        "c" : {
          "x" : 3463,
          "y" : 1011
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 3463,
          "y" : 1011
        }
      }
    }, {
      "edgeId" : 108517,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 3468,
          "y" : 971
        },
        "to" : {
          "x" : 3444,
          "y" : 942
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 3461,
          "y" : 968
        },
        "b" : {
          "x" : 3468,
          "y" : 971
        },
        "c" : {
          "x" : 3467,
          "y" : 963
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 3467,
          "y" : 963
        }
      }
    } ]
  }, {
    "id" : 108516,
    "reactomeId" : 10926810,
    "displayName" : "ACOX2:FAD",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 3388,
      "y" : 988
    },
    "minX" : 3350,
    "maxX" : 3433,
    "minY" : 949,
    "maxY" : 1035,
    "prop" : {
      "x" : 3350,
      "y" : 977,
      "width" : 77,
      "height" : 23
    },
    "textPosition" : {
      "x" : 3350,
      "y" : 979
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 3427,
          "y" : 977
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 3427,
          "y" : 977
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 108512,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 3387,
          "y" : 1003
        },
        "to" : {
          "x" : 3387,
          "y" : 1027
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 3387,
          "y" : 1031
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 3387,
          "y" : 1031
        }
      }
    }, {
      "edgeId" : 108517,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 3388,
          "y" : 974
        },
        "to" : {
          "x" : 3390,
          "y" : 957
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 3390,
          "y" : 953
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 3390,
          "y" : 953
        }
      }
    } ]
  }, {
    "id" : 108518,
    "reactomeId" : 193459,
    "displayName" : "25(S) 3alpha,7alpha-dihydroxy-5beta-cholest-24-enoyl-CoA",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 3534,
      "y" : 893
    },
    "minX" : 3444,
    "maxX" : 3618,
    "minY" : 863,
    "maxY" : 942,
    "prop" : {
      "x" : 3465,
      "y" : 864,
      "width" : 139,
      "height" : 59
    },
    "textPosition" : {
      "x" : 3475,
      "y" : 862
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 3599,
          "y" : 869
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 3599,
          "y" : 869
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 108517,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 3479,
          "y" : 926
        },
        "to" : {
          "x" : 3444,
          "y" : 942
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 3474,
          "y" : 933
        },
        "b" : {
          "x" : 3479,
          "y" : 926
        },
        "c" : {
          "x" : 3471,
          "y" : 925
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 3471,
          "y" : 925
        }
      }
    }, {
      "edgeId" : 108523,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 3586,
          "y" : 926
        },
        "to" : {
          "x" : 3618,
          "y" : 940
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 108521,
    "reactomeId" : 193422,
    "displayName" : "(24R, 25R) 3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestanoyl-CoA",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 3764,
      "y" : 1062
    },
    "minX" : 3698,
    "maxX" : 3851,
    "minY" : 1025,
    "maxY" : 1099,
    "prop" : {
      "x" : 3698,
      "y" : 1026,
      "width" : 133,
      "height" : 73
    },
    "textPosition" : {
      "x" : 3699,
      "y" : 1031
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 3826,
          "y" : 1031
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 3826,
          "y" : 1031
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 108579,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 108519,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 108525,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 3834,
          "y" : 1047
        },
        "to" : {
          "x" : 3851,
          "y" : 1043
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 108520,
    "reactomeId" : 141343,
    "displayName" : "H2O",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 3599,
      "y" : 989
    },
    "minX" : 3578,
    "maxX" : 3622,
    "minY" : 940,
    "maxY" : 1040,
    "prop" : {
      "x" : 3578,
      "y" : 974,
      "width" : 43,
      "height" : 31
    },
    "textPosition" : {
      "x" : 3582,
      "y" : 979
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 3616,
          "y" : 979
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 3616,
          "y" : 979
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 108519,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 3604,
          "y" : 1008
        },
        "to" : {
          "x" : 3618,
          "y" : 1040
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 108523,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 3605,
          "y" : 971
        },
        "to" : {
          "x" : 3618,
          "y" : 940
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ],
    "trivial" : true
  }, {
    "id" : 108522,
    "reactomeId" : 10926773,
    "displayName" : "HSD17B4 dimer",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 3685,
      "y" : 991
    },
    "minX" : 3634,
    "maxX" : 3874,
    "minY" : 945,
    "maxY" : 1041,
    "prop" : {
      "x" : 3634,
      "y" : 980,
      "width" : 102,
      "height" : 23
    },
    "textPosition" : {
      "x" : 3650,
      "y" : 968
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 3736,
          "y" : 980
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 3736,
          "y" : 980
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 108519,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 3674,
          "y" : 1006
        },
        "to" : {
          "x" : 3653,
          "y" : 1028
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 3650,
          "y" : 1031
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 3650,
          "y" : 1031
        }
      }
    }, {
      "edgeId" : 108523,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 3675,
          "y" : 977
        },
        "to" : {
          "x" : 3653,
          "y" : 953
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 3650,
          "y" : 950
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 3650,
          "y" : 950
        }
      }
    }, {
      "edgeId" : 108525,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 3731,
          "y" : 1006
        },
        "to" : {
          "x" : 3866,
          "y" : 1036
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 3870,
          "y" : 1037
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 3870,
          "y" : 1037
        }
      }
    }, {
      "edgeId" : 108530,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 3735,
          "y" : 977
        },
        "to" : {
          "x" : 3863,
          "y" : 950
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 3867,
          "y" : 949
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 3867,
          "y" : 949
        }
      }
    } ]
  }, {
    "id" : 108524,
    "reactomeId" : 193732,
    "displayName" : "3,7,24THCA-CoA",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 3764,
      "y" : 909
    },
    "minX" : 3706,
    "maxX" : 3840,
    "minY" : 893,
    "maxY" : 932,
    "prop" : {
      "x" : 3706,
      "y" : 894,
      "width" : 117,
      "height" : 31
    },
    "textPosition" : {
      "x" : 3710,
      "y" : 899
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 3818,
          "y" : 899
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 3818,
          "y" : 899
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 108523,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 108530,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 3815,
          "y" : 928
        },
        "to" : {
          "x" : 3840,
          "y" : 932
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 108527,
    "reactomeId" : 192305,
    "displayName" : "NADH",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 3900,
      "y" : 988
    },
    "minX" : 3874,
    "maxX" : 3927,
    "minY" : 949,
    "maxY" : 1039,
    "prop" : {
      "x" : 3874,
      "y" : 973,
      "width" : 52,
      "height" : 31
    },
    "textPosition" : {
      "x" : 3878,
      "y" : 978
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 3921,
          "y" : 978
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 3921,
          "y" : 978
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 108525,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 3899,
          "y" : 1007
        },
        "to" : {
          "x" : 3899,
          "y" : 1039
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 3903,
          "y" : 1014
        },
        "b" : {
          "x" : 3899,
          "y" : 1007
        },
        "c" : {
          "x" : 3895,
          "y" : 1014
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 3895,
          "y" : 1014
        }
      }
    }, {
      "edgeId" : 108530,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 3902,
          "y" : 970
        },
        "to" : {
          "x" : 3907,
          "y" : 949
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 3900,
          "y" : 962
        },
        "b" : {
          "x" : 3902,
          "y" : 970
        },
        "c" : {
          "x" : 3907,
          "y" : 964
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 3907,
          "y" : 964
        }
      }
    } ]
  }, {
    "id" : 108526,
    "reactomeId" : 192307,
    "displayName" : "NAD+",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 3829,
      "y" : 989
    },
    "minX" : 3804,
    "maxX" : 3856,
    "minY" : 932,
    "maxY" : 1043,
    "prop" : {
      "x" : 3804,
      "y" : 974,
      "width" : 51,
      "height" : 31
    },
    "textPosition" : {
      "x" : 3807,
      "y" : 979
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 3850,
          "y" : 979
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 3850,
          "y" : 979
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 108525,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 3835,
          "y" : 1008
        },
        "to" : {
          "x" : 3851,
          "y" : 1043
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 108530,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 3831,
          "y" : 971
        },
        "to" : {
          "x" : 3840,
          "y" : 932
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 108529,
    "reactomeId" : 193465,
    "displayName" : "H+",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 3951,
      "y" : 988
    },
    "minX" : 3899,
    "maxX" : 3969,
    "minY" : 949,
    "maxY" : 1039,
    "prop" : {
      "x" : 3934,
      "y" : 973,
      "width" : 34,
      "height" : 31
    },
    "textPosition" : {
      "x" : 3937,
      "y" : 978
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 3963,
          "y" : 978
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 3963,
          "y" : 978
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 108525,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 3935,
          "y" : 1007
        },
        "to" : {
          "x" : 3899,
          "y" : 1039
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 3932,
          "y" : 1015
        },
        "b" : {
          "x" : 3935,
          "y" : 1007
        },
        "c" : {
          "x" : 3927,
          "y" : 1009
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 3927,
          "y" : 1009
        }
      }
    }, {
      "edgeId" : 108530,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 3933,
          "y" : 970
        },
        "to" : {
          "x" : 3907,
          "y" : 949
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 3925,
          "y" : 969
        },
        "b" : {
          "x" : 3933,
          "y" : 970
        },
        "c" : {
          "x" : 3930,
          "y" : 963
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 3930,
          "y" : 963
        }
      }
    } ],
    "trivial" : true
  }, {
    "id" : 108528,
    "reactomeId" : 192339,
    "displayName" : "3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-one-CoA",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 4005,
      "y" : 1040
    },
    "minX" : 3899,
    "maxX" : 4072,
    "minY" : 1003,
    "maxY" : 1077,
    "prop" : {
      "x" : 3940,
      "y" : 1004,
      "width" : 131,
      "height" : 73
    },
    "textPosition" : {
      "x" : 3942,
      "y" : 1009
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 4066,
          "y" : 1009
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 4066,
          "y" : 1009
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 108525,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 3937,
          "y" : 1039
        },
        "to" : {
          "x" : 3899,
          "y" : 1039
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 3930,
          "y" : 1043
        },
        "b" : {
          "x" : 3937,
          "y" : 1039
        },
        "c" : {
          "x" : 3930,
          "y" : 1035
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 3930,
          "y" : 1035
        }
      }
    } ]
  }, {
    "id" : 108531,
    "reactomeId" : 193403,
    "displayName" : "3alpha,7alpha-dihydroxy-5beta-cholest-24-one-CoA",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 4012,
      "y" : 926
    },
    "minX" : 3907,
    "maxX" : 4087,
    "minY" : 887,
    "maxY" : 965,
    "prop" : {
      "x" : 3939,
      "y" : 888,
      "width" : 147,
      "height" : 77
    },
    "textPosition" : {
      "x" : 3947,
      "y" : 902
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 4081,
          "y" : 893
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 4081,
          "y" : 893
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 108530,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 3936,
          "y" : 942
        },
        "to" : {
          "x" : 3907,
          "y" : 949
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 3930,
          "y" : 948
        },
        "b" : {
          "x" : 3936,
          "y" : 942
        },
        "c" : {
          "x" : 3928,
          "y" : 940
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 3928,
          "y" : 940
        }
      }
    } ]
  }, {
    "id" : 108533,
    "reactomeId" : 141343,
    "displayName" : "H2O",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 4396,
      "y" : 1145
    },
    "minX" : 4375,
    "maxX" : 4433,
    "minY" : 1129,
    "maxY" : 1161,
    "prop" : {
      "x" : 4375,
      "y" : 1130,
      "width" : 43,
      "height" : 31
    },
    "textPosition" : {
      "x" : 4379,
      "y" : 1135
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 4413,
          "y" : 1135
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 4413,
          "y" : 1135
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 108532,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 4421,
          "y" : 1135
        },
        "to" : {
          "x" : 4433,
          "y" : 1129
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ],
    "trivial" : true
  }, {
    "id" : 108535,
    "reactomeId" : 193451,
    "displayName" : "CCA",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 4544,
      "y" : 1146
    },
    "minX" : 4491,
    "maxX" : 4574,
    "minY" : 1129,
    "maxY" : 1162,
    "prop" : {
      "x" : 4515,
      "y" : 1131,
      "width" : 58,
      "height" : 31
    },
    "textPosition" : {
      "x" : 4528,
      "y" : 1136
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 4568,
          "y" : 1136
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 4568,
          "y" : 1136
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 108532,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 4512,
          "y" : 1136
        },
        "to" : {
          "x" : 4491,
          "y" : 1129
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 4504,
          "y" : 1138
        },
        "b" : {
          "x" : 4512,
          "y" : 1136
        },
        "c" : {
          "x" : 4507,
          "y" : 1130
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 4507,
          "y" : 1130
        }
      }
    } ]
  }, {
    "id" : 108534,
    "reactomeId" : 192356,
    "displayName" : "choloyl-CoA",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 4251,
      "y" : 1070
    },
    "minX" : 4210,
    "maxX" : 4433,
    "minY" : 1037,
    "maxY" : 1129,
    "prop" : {
      "x" : 4210,
      "y" : 1055,
      "width" : 83,
      "height" : 31
    },
    "textPosition" : {
      "x" : 4212,
      "y" : 1060
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 4288,
          "y" : 1060
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 4288,
          "y" : 1060
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 108532,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 4296,
          "y" : 1083
        },
        "to" : {
          "x" : 4433,
          "y" : 1129
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 108538,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 4274,
          "y" : 1052
        },
        "to" : {
          "x" : 4300,
          "y" : 1037
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 108537,
    "reactomeId" : 10926911,
    "displayName" : "ACOT8",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 4455,
      "y" : 1081
    },
    "minX" : 4430,
    "maxX" : 4486,
    "minY" : 1064,
    "maxY" : 1121,
    "prop" : {
      "x" : 4430,
      "y" : 1070,
      "width" : 50,
      "height" : 23
    },
    "textPosition" : {
      "x" : 4431,
      "y" : 1071
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 4480,
          "y" : 1070
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 4480,
          "y" : 1070
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 108532,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 4455,
          "y" : 1096
        },
        "to" : {
          "x" : 4456,
          "y" : 1113
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 4456,
          "y" : 1117
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 4456,
          "y" : 1117
        }
      }
    } ]
  }, {
    "id" : 108536,
    "reactomeId" : 193514,
    "displayName" : "CoA-SH",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 4549,
      "y" : 1085
    },
    "minX" : 4491,
    "maxX" : 4580,
    "minY" : 1069,
    "maxY" : 1129,
    "prop" : {
      "x" : 4520,
      "y" : 1070,
      "width" : 59,
      "height" : 31
    },
    "textPosition" : {
      "x" : 4523,
      "y" : 1075
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 4574,
          "y" : 1075
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 4574,
          "y" : 1075
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 108532,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 4528,
          "y" : 1104
        },
        "to" : {
          "x" : 4491,
          "y" : 1129
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 4524,
          "y" : 1111
        },
        "b" : {
          "x" : 4528,
          "y" : 1104
        },
        "c" : {
          "x" : 4520,
          "y" : 1105
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 4520,
          "y" : 1105
        }
      }
    } ]
  }, {
    "id" : 108539,
    "reactomeId" : 193463,
    "displayName" : "Gly, TAU",
    "schemaClass" : "DefinedSet",
    "renderableClass" : "EntitySet",
    "position" : {
      "x" : 4309,
      "y" : 986
    },
    "minX" : 4280,
    "maxX" : 4339,
    "minY" : 936,
    "maxY" : 1037,
    "prop" : {
      "x" : 4280,
      "y" : 975,
      "width" : 59,
      "height" : 23
    },
    "textPosition" : {
      "x" : 4280,
      "y" : 976
    },
    "connectors" : [ {
      "edgeId" : 108538,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 4306,
          "y" : 1004
        },
        "to" : {
          "x" : 4300,
          "y" : 1037
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 108543,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 4306,
          "y" : 969
        },
        "to" : {
          "x" : 4297,
          "y" : 936
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 108541,
    "reactomeId" : 193514,
    "displayName" : "CoA-SH",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 4477,
      "y" : 986
    },
    "minX" : 4422,
    "maxX" : 4508,
    "minY" : 937,
    "maxY" : 1037,
    "prop" : {
      "x" : 4448,
      "y" : 971,
      "width" : 59,
      "height" : 31
    },
    "textPosition" : {
      "x" : 4451,
      "y" : 976
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 4502,
          "y" : 976
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 4502,
          "y" : 976
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 108538,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 4460,
          "y" : 1005
        },
        "to" : {
          "x" : 4423,
          "y" : 1037
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 4457,
          "y" : 1013
        },
        "b" : {
          "x" : 4460,
          "y" : 1005
        },
        "c" : {
          "x" : 4452,
          "y" : 1007
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 4452,
          "y" : 1007
        }
      }
    }, {
      "edgeId" : 108543,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 4459,
          "y" : 968
        },
        "to" : {
          "x" : 4422,
          "y" : 937
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 4451,
          "y" : 967
        },
        "b" : {
          "x" : 4459,
          "y" : 968
        },
        "c" : {
          "x" : 4456,
          "y" : 960
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 4456,
          "y" : 960
        }
      }
    } ]
  }, {
    "id" : 108540,
    "reactomeId" : 193404,
    "displayName" : "cholate bile salts",
    "schemaClass" : "DefinedSet",
    "renderableClass" : "EntitySet",
    "position" : {
      "x" : 4514,
      "y" : 1037
    },
    "minX" : 4423,
    "maxX" : 4567,
    "minY" : 1026,
    "maxY" : 1049,
    "prop" : {
      "x" : 4462,
      "y" : 1026,
      "width" : 105,
      "height" : 23
    },
    "textPosition" : {
      "x" : 4472,
      "y" : 1020
    },
    "connectors" : [ {
      "edgeId" : 108538,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 4456,
          "y" : 1037
        },
        "to" : {
          "x" : 4423,
          "y" : 1037
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 4449,
          "y" : 1041
        },
        "b" : {
          "x" : 4456,
          "y" : 1037
        },
        "c" : {
          "x" : 4449,
          "y" : 1033
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 4449,
          "y" : 1033
        }
      }
    } ]
  }, {
    "id" : 108542,
    "reactomeId" : 10926763,
    "displayName" : "Homologues of BAAT",
    "schemaClass" : "DefinedSet",
    "renderableClass" : "EntitySet",
    "position" : {
      "x" : 4383,
      "y" : 986
    },
    "minX" : 4363,
    "maxX" : 4403,
    "minY" : 945,
    "maxY" : 1029,
    "prop" : {
      "x" : 4363,
      "y" : 975,
      "width" : 40,
      "height" : 23
    },
    "textPosition" : {
      "x" : 4363,
      "y" : 948
    },
    "connectors" : [ {
      "edgeId" : 108538,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 4383,
          "y" : 1001
        },
        "to" : {
          "x" : 4383,
          "y" : 1021
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 4383,
          "y" : 1025
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 4383,
          "y" : 1025
        }
      }
    }, {
      "edgeId" : 108543,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 4382,
          "y" : 972
        },
        "to" : {
          "x" : 4381,
          "y" : 953
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 4381,
          "y" : 949
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 4381,
          "y" : 949
        }
      }
    } ]
  } ],
  "edges" : [ {
    "id" : 108480,
    "reactomeId" : 10926720,
    "displayName" : "4-cholesten-7alpha-ol-3-one is reduced to 5beta-cholestan-7alpha-ol-3-one",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 980,
      "y" : 914
    },
    "minX" : 931,
    "maxX" : 1004,
    "minY" : 908,
    "maxY" : 920,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 931,
        "y" : 915
      },
      "to" : {
        "x" : 980,
        "y" : 914
      }
    }, {
      "from" : {
        "x" : 980,
        "y" : 914
      },
      "to" : {
        "x" : 1004,
        "y" : 915
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 974,
        "y" : 908
      },
      "b" : {
        "x" : 986,
        "y" : 920
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 980,
        "y" : 914
      }
    },
    "inputs" : [ {
      "id" : 108481,
      "points" : [ {
        "x" : 735,
        "y" : 897
      } ]
    }, {
      "id" : 108475,
      "points" : [ {
        "x" : 917,
        "y" : 955
      } ]
    }, {
      "id" : 108476,
      "points" : [ {
        "x" : 876,
        "y" : 955
      } ]
    } ],
    "outputs" : [ {
      "id" : 108482,
      "points" : [ {
        "x" : 1042,
        "y" : 912
      } ]
    }, {
      "id" : 108478,
      "points" : [ {
        "x" : 1057,
        "y" : 953
      } ]
    } ],
    "catalysts" : [ {
      "id" : 108479,
      "points" : [ {
        "x" : 980,
        "y" : 959
      } ]
    } ]
  }, {
    "id" : 108483,
    "reactomeId" : 10926739,
    "displayName" : "5Beta-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha, 12alpha-triol",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 1261,
      "y" : 1034
    },
    "minX" : 1206,
    "maxX" : 1297,
    "minY" : 1028,
    "maxY" : 1040,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 1206,
        "y" : 1035
      },
      "to" : {
        "x" : 1261,
        "y" : 1034
      }
    }, {
      "from" : {
        "x" : 1261,
        "y" : 1034
      },
      "to" : {
        "x" : 1297,
        "y" : 1034
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 1255,
        "y" : 1028
      },
      "b" : {
        "x" : 1267,
        "y" : 1040
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 1261,
        "y" : 1034
      }
    },
    "inputs" : [ {
      "id" : 108477,
      "points" : [ {
        "x" : 1177,
        "y" : 1035
      } ]
    }, {
      "id" : 108484,
      "points" : [ {
        "x" : 1195,
        "y" : 993
      } ]
    }, {
      "id" : 108485,
      "points" : [ {
        "x" : 1156,
        "y" : 992
      } ]
    } ],
    "outputs" : [ {
      "id" : 108486,
      "points" : [ {
        "x" : 1319,
        "y" : 1045
      } ]
    }, {
      "id" : 108487,
      "points" : [ {
        "x" : 1335,
        "y" : 995
      } ]
    } ],
    "catalysts" : [ {
      "id" : 108488,
      "points" : [ {
        "x" : 1259,
        "y" : 1000
      } ]
    } ]
  }, {
    "id" : 108546,
    "reactomeId" : 10926952,
    "displayName" : "4-cholesten-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,24(S)-triol-3-one",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 993,
      "y" : 568
    },
    "minX" : 904,
    "maxX" : 1015,
    "minY" : 562,
    "maxY" : 584,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 904,
        "y" : 584
      },
      "to" : {
        "x" : 993,
        "y" : 568
      }
    }, {
      "from" : {
        "x" : 993,
        "y" : 568
      },
      "to" : {
        "x" : 1015,
        "y" : 567
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 987,
        "y" : 562
      },
      "b" : {
        "x" : 999,
        "y" : 574
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 993,
        "y" : 568
      }
    },
    "inputs" : [ {
      "id" : 108547,
      "points" : [ {
        "x" : 758,
        "y" : 584
      } ]
    }, {
      "id" : 108548,
      "points" : [ {
        "x" : 868,
        "y" : 538
      } ]
    }, {
      "id" : 108549,
      "points" : [ {
        "x" : 910,
        "y" : 539
      } ]
    } ],
    "outputs" : [ {
      "id" : 108550,
      "points" : [ {
        "x" : 1041,
        "y" : 567
      } ]
    }, {
      "id" : 108551,
      "points" : [ {
        "x" : 1057,
        "y" : 538
      } ]
    } ],
    "catalysts" : [ {
      "id" : 108552,
      "points" : [ {
        "x" : 988,
        "y" : 534
      } ]
    } ]
  }, {
    "id" : 108610,
    "reactomeId" : 10927007,
    "displayName" : "SLC10A2 transports bile salts and acids and Na+ from extracellular region to cytosol",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 5235,
      "y" : 913
    },
    "minX" : 5229,
    "maxX" : 5241,
    "minY" : 879,
    "maxY" : 952,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 5235,
        "y" : 879
      },
      "to" : {
        "x" : 5235,
        "y" : 913
      }
    }, {
      "from" : {
        "x" : 5235,
        "y" : 913
      },
      "to" : {
        "x" : 5235,
        "y" : 952
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 5229,
        "y" : 907
      },
      "b" : {
        "x" : 5241,
        "y" : 919
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 5235,
        "y" : 913
      }
    },
    "inputs" : [ {
      "id" : 108611,
      "points" : [ {
        "x" : 5278,
        "y" : 861
      } ]
    }, {
      "id" : 108612,
      "points" : [ {
        "x" : 5182,
        "y" : 862
      } ]
    } ],
    "outputs" : [ {
      "id" : 108613,
      "points" : [ {
        "x" : 5274,
        "y" : 965
      } ]
    }, {
      "id" : 108614,
      "points" : [ {
        "x" : 5235,
        "y" : 1035
      } ]
    } ],
    "catalysts" : [ {
      "id" : 108615,
      "points" : [ {
        "x" : 5205,
        "y" : 913
      } ]
    } ]
  }, {
    "id" : 108553,
    "reactomeId" : 10926950,
    "displayName" : "4-cholesten-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-7alpha,24(S)-diol-3-one",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 994,
      "y" : 461
    },
    "minX" : 903,
    "maxX" : 1022,
    "minY" : 433,
    "maxY" : 467,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 903,
        "y" : 433
      },
      "to" : {
        "x" : 994,
        "y" : 461
      }
    }, {
      "from" : {
        "x" : 994,
        "y" : 461
      },
      "to" : {
        "x" : 1022,
        "y" : 462
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 988,
        "y" : 455
      },
      "b" : {
        "x" : 1000,
        "y" : 467
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 994,
        "y" : 461
      }
    },
    "inputs" : [ {
      "id" : 108554,
      "points" : [ {
        "x" : 744,
        "y" : 411
      } ]
    }, {
      "id" : 108549,
      "points" : [ {
        "x" : 910,
        "y" : 502
      } ]
    }, {
      "id" : 108548,
      "points" : [ {
        "x" : 866,
        "y" : 501
      } ]
    } ],
    "outputs" : [ {
      "id" : 108555,
      "points" : [ {
        "x" : 1036,
        "y" : 462
      } ]
    }, {
      "id" : 108551,
      "points" : [ {
        "x" : 1062,
        "y" : 501
      } ]
    } ],
    "catalysts" : [ {
      "id" : 108552,
      "points" : [ {
        "x" : 988,
        "y" : 505
      } ]
    } ]
  }, {
    "id" : 108489,
    "reactomeId" : 10926753,
    "displayName" : "5beta-cholestan-7alpha-ol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha-diol",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 1254,
      "y" : 914
    },
    "minX" : 1196,
    "maxX" : 1299,
    "minY" : 908,
    "maxY" : 920,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 1196,
        "y" : 914
      },
      "to" : {
        "x" : 1254,
        "y" : 914
      }
    }, {
      "from" : {
        "x" : 1254,
        "y" : 914
      },
      "to" : {
        "x" : 1299,
        "y" : 914
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 1248,
        "y" : 908
      },
      "b" : {
        "x" : 1260,
        "y" : 920
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 1254,
        "y" : 914
      }
    },
    "inputs" : [ {
      "id" : 108482,
      "points" : [ {
        "x" : 1161,
        "y" : 911
      } ]
    }, {
      "id" : 108484,
      "points" : [ {
        "x" : 1193,
        "y" : 956
      } ]
    }, {
      "id" : 108485,
      "points" : [ {
        "x" : 1154,
        "y" : 955
      } ]
    } ],
    "outputs" : [ {
      "id" : 108490,
      "points" : [ {
        "x" : 1327,
        "y" : 896
      } ]
    }, {
      "id" : 108487,
      "points" : [ {
        "x" : 1336,
        "y" : 958
      } ]
    } ],
    "catalysts" : [ {
      "id" : 108488,
      "points" : [ {
        "x" : 1256,
        "y" : 942
      } ]
    } ]
  }, {
    "id" : 108616,
    "reactomeId" : 10926989,
    "displayName" : "SLC10A1 co-transport bile salts and Na+ from extracellular region to cytosol",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 4769,
      "y" : 1280
    },
    "minX" : 4731,
    "maxX" : 4822,
    "minY" : 1274,
    "maxY" : 1286,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 4822,
        "y" : 1280
      },
      "to" : {
        "x" : 4769,
        "y" : 1280
      }
    }, {
      "from" : {
        "x" : 4769,
        "y" : 1280
      },
      "to" : {
        "x" : 4731,
        "y" : 1279
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 4763,
        "y" : 1274
      },
      "b" : {
        "x" : 4775,
        "y" : 1286
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 4769,
        "y" : 1280
      }
    },
    "inputs" : [ {
      "id" : 108617,
      "points" : [ {
        "x" : 4913,
        "y" : 1303
      } ]
    }, {
      "id" : 108618,
      "points" : [ {
        "x" : 4865,
        "y" : 1252
      } ],
      "stoichiometry" : 2
    } ],
    "outputs" : [ {
      "id" : 108619,
      "points" : [ {
        "x" : 4690,
        "y" : 1247
      } ],
      "stoichiometry" : 2
    }, {
      "id" : 108620,
      "points" : [ {
        "x" : 4696,
        "y" : 1300
      } ]
    } ],
    "catalysts" : [ {
      "id" : 108621,
      "points" : [ {
        "x" : 4769,
        "y" : 1243
      } ]
    } ]
  }, {
    "id" : 108491,
    "reactomeId" : 10926923,
    "displayName" : "THCA is conjugated with Coenzyme A (SLC27A2 VLCS)",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 2707,
      "y" : 1111
    },
    "minX" : 2652,
    "maxX" : 2791,
    "minY" : 1105,
    "maxY" : 1117,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 2652,
        "y" : 1112
      },
      "to" : {
        "x" : 2707,
        "y" : 1111
      }
    }, {
      "from" : {
        "x" : 2707,
        "y" : 1111
      },
      "to" : {
        "x" : 2791,
        "y" : 1110
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 2701,
        "y" : 1105
      },
      "b" : {
        "x" : 2713,
        "y" : 1117
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 2707,
        "y" : 1111
      }
    },
    "inputs" : [ {
      "id" : 108492,
      "points" : [ {
        "x" : 2571,
        "y" : 1059
      } ]
    }, {
      "id" : 108493,
      "points" : [ {
        "x" : 2555,
        "y" : 1002
      } ]
    }, {
      "id" : 108494,
      "points" : [ {
        "x" : 2635,
        "y" : 1005
      } ]
    } ],
    "outputs" : [ {
      "id" : 108495,
      "points" : [ {
        "x" : 2936,
        "y" : 1060
      } ]
    }, {
      "id" : 108496,
      "points" : [ {
        "x" : 2867,
        "y" : 1006
      } ]
    }, {
      "id" : 108497,
      "points" : [ {
        "x" : 2962,
        "y" : 999
      } ]
    } ],
    "catalysts" : [ {
      "id" : 108498,
      "points" : [ {
        "x" : 2704,
        "y" : 1046
      } ]
    } ]
  }, {
    "id" : 108556,
    "reactomeId" : 10926960,
    "displayName" : "5Beta-cholestan-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,24(S)-tetrol",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 1272,
      "y" : 569
    },
    "minX" : 1200,
    "maxX" : 1297,
    "minY" : 563,
    "maxY" : 575,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 1200,
        "y" : 568
      },
      "to" : {
        "x" : 1272,
        "y" : 569
      }
    }, {
      "from" : {
        "x" : 1272,
        "y" : 569
      },
      "to" : {
        "x" : 1297,
        "y" : 569
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 1266,
        "y" : 563
      },
      "b" : {
        "x" : 1278,
        "y" : 575
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 1272,
        "y" : 569
      }
    },
    "inputs" : [ {
      "id" : 108550,
      "points" : [ {
        "x" : 1176,
        "y" : 567
      } ]
    }, {
      "id" : 108557,
      "points" : [ {
        "x" : 1161,
        "y" : 538
      } ]
    }, {
      "id" : 108558,
      "points" : [ {
        "x" : 1196,
        "y" : 538
      } ]
    } ],
    "outputs" : [ {
      "id" : 108559,
      "points" : [ {
        "x" : 1316,
        "y" : 586
      } ]
    }, {
      "id" : 108560,
      "points" : [ {
        "x" : 1344,
        "y" : 536
      } ]
    } ],
    "catalysts" : [ {
      "id" : 108561,
      "points" : [ {
        "x" : 1269,
        "y" : 547
      } ]
    } ]
  }, {
    "id" : 108622,
    "reactomeId" : 10926994,
    "displayName" : "Transport (influx) of bile salts and acids by OATP-A",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 4771,
      "y" : 1320
    },
    "minX" : 4721,
    "maxX" : 4884,
    "minY" : 1314,
    "maxY" : 1326,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 4884,
        "y" : 1320
      },
      "to" : {
        "x" : 4771,
        "y" : 1320
      }
    }, {
      "from" : {
        "x" : 4771,
        "y" : 1320
      },
      "to" : {
        "x" : 4721,
        "y" : 1321
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 4728,
        "y" : 1317
      },
      "b" : {
        "x" : 4721,
        "y" : 1321
      },
      "c" : {
        "x" : 4728,
        "y" : 1325
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 4728,
        "y" : 1325
      }
    },
    "reactionShape" : {
      "a" : {
        "x" : 4765,
        "y" : 1314
      },
      "b" : {
        "x" : 4777,
        "y" : 1326
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 4771,
        "y" : 1320
      }
    },
    "inputs" : [ {
      "id" : 108617
    } ],
    "outputs" : [ {
      "id" : 108620
    } ],
    "catalysts" : [ {
      "id" : 108623,
      "points" : [ {
        "x" : 4771,
        "y" : 1352
      } ]
    } ]
  }, {
    "id" : 108624,
    "reactomeId" : 10926981,
    "displayName" : "SLCO1B1 transports ALB:(GCCA,TCCA) from extracellular region to cytosol",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 4770,
      "y" : 1595
    },
    "minX" : 4699,
    "maxX" : 4841,
    "minY" : 1563,
    "maxY" : 1601,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 4841,
        "y" : 1568
      },
      "to" : {
        "x" : 4770,
        "y" : 1595
      }
    }, {
      "from" : {
        "x" : 4770,
        "y" : 1595
      },
      "to" : {
        "x" : 4699,
        "y" : 1563
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 4707,
        "y" : 1562
      },
      "b" : {
        "x" : 4699,
        "y" : 1563
      },
      "c" : {
        "x" : 4704,
        "y" : 1569
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 4704,
        "y" : 1569
      }
    },
    "reactionShape" : {
      "a" : {
        "x" : 4764,
        "y" : 1589
      },
      "b" : {
        "x" : 4776,
        "y" : 1601
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 4770,
        "y" : 1595
      }
    },
    "inputs" : [ {
      "id" : 108625
    } ],
    "outputs" : [ {
      "id" : 108626
    } ],
    "catalysts" : [ {
      "id" : 108627,
      "points" : [ {
        "x" : 4770,
        "y" : 1620
      } ]
    } ]
  }, {
    "id" : 108499,
    "reactomeId" : 10926927,
    "displayName" : "DHCA is conjugated with Coenzyme A (SLC27A2 VLCS)",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 2700,
      "y" : 877
    },
    "minX" : 2638,
    "maxX" : 2795,
    "minY" : 871,
    "maxY" : 883,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 2638,
        "y" : 877
      },
      "to" : {
        "x" : 2700,
        "y" : 877
      }
    }, {
      "from" : {
        "x" : 2700,
        "y" : 877
      },
      "to" : {
        "x" : 2795,
        "y" : 876
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 2694,
        "y" : 871
      },
      "b" : {
        "x" : 2706,
        "y" : 883
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 2700,
        "y" : 877
      }
    },
    "inputs" : [ {
      "id" : 108500,
      "points" : [ {
        "x" : 2578,
        "y" : 912
      } ]
    }, {
      "id" : 108494,
      "points" : [ {
        "x" : 2633,
        "y" : 968
      } ]
    }, {
      "id" : 108493,
      "points" : [ {
        "x" : 2556,
        "y" : 965
      } ]
    } ],
    "outputs" : [ {
      "id" : 108496,
      "points" : [ {
        "x" : 2866,
        "y" : 969
      } ]
    }, {
      "id" : 108497,
      "points" : [ {
        "x" : 2962,
        "y" : 978
      } ]
    }, {
      "id" : 108501,
      "points" : [ {
        "x" : 2931,
        "y" : 918
      } ]
    } ],
    "catalysts" : [ {
      "id" : 108498,
      "points" : [ {
        "x" : 2703,
        "y" : 1017
      } ]
    } ]
  }, {
    "id" : 108562,
    "reactomeId" : 10926954,
    "displayName" : "5beta-cholestan-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,24(S)-triol",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 1270,
      "y" : 467
    },
    "minX" : 1203,
    "maxX" : 1295,
    "minY" : 461,
    "maxY" : 473,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 1203,
        "y" : 467
      },
      "to" : {
        "x" : 1270,
        "y" : 467
      }
    }, {
      "from" : {
        "x" : 1270,
        "y" : 467
      },
      "to" : {
        "x" : 1295,
        "y" : 467
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 1264,
        "y" : 461
      },
      "b" : {
        "x" : 1276,
        "y" : 473
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 1270,
        "y" : 467
      }
    },
    "inputs" : [ {
      "id" : 108555,
      "points" : [ {
        "x" : 1174,
        "y" : 466
      } ]
    }, {
      "id" : 108557,
      "points" : [ {
        "x" : 1160,
        "y" : 501
      } ]
    }, {
      "id" : 108558,
      "points" : [ {
        "x" : 1197,
        "y" : 501
      } ]
    } ],
    "outputs" : [ {
      "id" : 108563,
      "points" : [ {
        "x" : 1320,
        "y" : 439
      } ]
    }, {
      "id" : 108560,
      "points" : [ {
        "x" : 1342,
        "y" : 499
      } ]
    } ],
    "catalysts" : [ {
      "id" : 108561,
      "points" : [ {
        "x" : 1268,
        "y" : 487
      } ]
    } ]
  }, {
    "id" : 108564,
    "reactomeId" : 10926958,
    "displayName" : "TetraHCA is conjugated with Coenzyme A (SLC27A5 BACS)",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 2755,
      "y" : 416
    },
    "minX" : 2658,
    "maxX" : 2793,
    "minY" : 410,
    "maxY" : 422,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 2658,
        "y" : 416
      },
      "to" : {
        "x" : 2755,
        "y" : 416
      }
    }, {
      "from" : {
        "x" : 2755,
        "y" : 416
      },
      "to" : {
        "x" : 2793,
        "y" : 416
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 2749,
        "y" : 410
      },
      "b" : {
        "x" : 2761,
        "y" : 422
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 2755,
        "y" : 416
      }
    },
    "inputs" : [ {
      "id" : 108565,
      "points" : [ {
        "x" : 2572,
        "y" : 501
      } ]
    }, {
      "id" : 108566,
      "points" : [ {
        "x" : 2562,
        "y" : 600
      } ]
    }, {
      "id" : 108567,
      "points" : [ {
        "x" : 2644,
        "y" : 500
      } ]
    } ],
    "outputs" : [ {
      "id" : 108568,
      "points" : [ {
        "x" : 2914,
        "y" : 437
      } ]
    }, {
      "id" : 108569,
      "points" : [ {
        "x" : 2836,
        "y" : 501
      } ]
    }, {
      "id" : 108570,
      "points" : [ {
        "x" : 2876,
        "y" : 501
      } ]
    }, {
      "id" : 108571,
      "points" : [ {
        "x" : 2962,
        "y" : 517
      } ]
    } ],
    "catalysts" : [ {
      "id" : 108572,
      "points" : [ {
        "x" : 2775,
        "y" : 473
      } ]
    } ]
  }, {
    "id" : 108628,
    "reactomeId" : 10926976,
    "displayName" : "SLCO1B3 transports ALB:(GCCA, TCCA) from extracellular region to cytosol",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 4771,
      "y" : 1517
    },
    "minX" : 4716,
    "maxX" : 4832,
    "minY" : 1511,
    "maxY" : 1533,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 4832,
        "y" : 1533
      },
      "to" : {
        "x" : 4771,
        "y" : 1517
      }
    }, {
      "from" : {
        "x" : 4771,
        "y" : 1517
      },
      "to" : {
        "x" : 4716,
        "y" : 1528
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 4722,
        "y" : 1523
      },
      "b" : {
        "x" : 4716,
        "y" : 1528
      },
      "c" : {
        "x" : 4724,
        "y" : 1531
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 4724,
        "y" : 1531
      }
    },
    "reactionShape" : {
      "a" : {
        "x" : 4765,
        "y" : 1511
      },
      "b" : {
        "x" : 4777,
        "y" : 1523
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 4771,
        "y" : 1517
      }
    },
    "inputs" : [ {
      "id" : 108625
    } ],
    "outputs" : [ {
      "id" : 108626
    } ],
    "catalysts" : [ {
      "id" : 108629,
      "points" : [ {
        "x" : 4770,
        "y" : 1483
      } ]
    } ]
  }, {
    "id" : 108630,
    "reactomeId" : 10922678,
    "displayName" : "Cytosolic cholate and chenodeoxycholate are conjugated with Coenzyme A (SLC27A5 BACS)",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 4531,
      "y" : 1470
    },
    "minX" : 4525,
    "maxX" : 4537,
    "minY" : 1435,
    "maxY" : 1491,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 4531,
        "y" : 1491
      },
      "to" : {
        "x" : 4531,
        "y" : 1470
      }
    }, {
      "from" : {
        "x" : 4531,
        "y" : 1470
      },
      "to" : {
        "x" : 4531,
        "y" : 1435
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 4525,
        "y" : 1464
      },
      "b" : {
        "x" : 4537,
        "y" : 1476
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 4531,
        "y" : 1470
      }
    },
    "inputs" : [ {
      "id" : 108631,
      "points" : [ {
        "x" : 4518,
        "y" : 1496
      } ]
    }, {
      "id" : 108632,
      "points" : [ {
        "x" : 4532,
        "y" : 1545
      } ]
    }, {
      "id" : 108633,
      "points" : [ {
        "x" : 4547,
        "y" : 1497
      } ]
    } ],
    "outputs" : [ {
      "id" : 108634,
      "points" : [ {
        "x" : 4564,
        "y" : 1446
      } ]
    }, {
      "id" : 108635,
      "points" : [ {
        "x" : 4531,
        "y" : 1391
      } ]
    }, {
      "id" : 108636,
      "points" : [ {
        "x" : 4558,
        "y" : 1420
      } ]
    }, {
      "id" : 108637,
      "points" : [ {
        "x" : 4498,
        "y" : 1422
      } ]
    } ],
    "catalysts" : [ {
      "id" : 108638,
      "points" : [ {
        "x" : 4440,
        "y" : 1470
      } ]
    } ]
  }, {
    "id" : 108502,
    "reactomeId" : 10926751,
    "displayName" : "THCA is conjugated with Coenzyme A (SLC27A5 BACS)",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 2754,
      "y" : 896
    },
    "minX" : 2656,
    "maxX" : 2793,
    "minY" : 890,
    "maxY" : 902,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 2656,
        "y" : 897
      },
      "to" : {
        "x" : 2754,
        "y" : 896
      }
    }, {
      "from" : {
        "x" : 2754,
        "y" : 896
      },
      "to" : {
        "x" : 2793,
        "y" : 895
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 2748,
        "y" : 890
      },
      "b" : {
        "x" : 2760,
        "y" : 902
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 2754,
        "y" : 896
      }
    },
    "inputs" : [ {
      "id" : 108492,
      "points" : [ {
        "x" : 2561,
        "y" : 1022
      } ]
    }, {
      "id" : 108494,
      "points" : [ {
        "x" : 2637,
        "y" : 968
      } ]
    }, {
      "id" : 108493,
      "points" : [ {
        "x" : 2562,
        "y" : 965
      } ]
    } ],
    "outputs" : [ {
      "id" : 108495,
      "points" : [ {
        "x" : 2959,
        "y" : 1023
      } ]
    }, {
      "id" : 108496,
      "points" : [ {
        "x" : 2863,
        "y" : 969
      } ]
    }, {
      "id" : 108497,
      "points" : [ {
        "x" : 2962,
        "y" : 980
      } ]
    } ],
    "catalysts" : [ {
      "id" : 108503,
      "points" : [ {
        "x" : 2801,
        "y" : 977
      } ]
    } ]
  }, {
    "id" : 108505,
    "reactomeId" : 10926747,
    "displayName" : "Isomerization of 25(R) THCA-CoA to 25(S) THCA-CoA",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 3213,
      "y" : 1039
    },
    "minX" : 3171,
    "maxX" : 3268,
    "minY" : 1033,
    "maxY" : 1063,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 3171,
        "y" : 1063
      },
      "to" : {
        "x" : 3213,
        "y" : 1039
      }
    }, {
      "from" : {
        "x" : 3213,
        "y" : 1039
      },
      "to" : {
        "x" : 3268,
        "y" : 1062
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 3260,
        "y" : 1063
      },
      "b" : {
        "x" : 3268,
        "y" : 1062
      },
      "c" : {
        "x" : 3263,
        "y" : 1056
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 3263,
        "y" : 1056
      }
    },
    "reactionShape" : {
      "a" : {
        "x" : 3207,
        "y" : 1033
      },
      "b" : {
        "x" : 3219,
        "y" : 1045
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 3213,
        "y" : 1039
      }
    },
    "inputs" : [ {
      "id" : 108506
    } ],
    "outputs" : [ {
      "id" : 108507
    } ],
    "catalysts" : [ {
      "id" : 108508,
      "points" : [ {
        "x" : 3213,
        "y" : 796
      } ]
    } ]
  }, {
    "id" : 108504,
    "reactomeId" : 10926925,
    "displayName" : "DHCA is conjugated with Coenzyme A (SLC27A5 BACS)",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 2761,
      "y" : 1082
    },
    "minX" : 2659,
    "maxX" : 2792,
    "minY" : 1076,
    "maxY" : 1088,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 2659,
        "y" : 1081
      },
      "to" : {
        "x" : 2761,
        "y" : 1082
      }
    }, {
      "from" : {
        "x" : 2761,
        "y" : 1082
      },
      "to" : {
        "x" : 2792,
        "y" : 1082
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 2755,
        "y" : 1076
      },
      "b" : {
        "x" : 2767,
        "y" : 1088
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 2761,
        "y" : 1082
      }
    },
    "inputs" : [ {
      "id" : 108494,
      "points" : [ {
        "x" : 2637,
        "y" : 1005
      } ]
    }, {
      "id" : 108500,
      "points" : [ {
        "x" : 2560,
        "y" : 946
      } ]
    }, {
      "id" : 108493,
      "points" : [ {
        "x" : 2560,
        "y" : 1002
      } ]
    } ],
    "outputs" : [ {
      "id" : 108496,
      "points" : [ {
        "x" : 2863,
        "y" : 1006
      } ]
    }, {
      "id" : 108497,
      "points" : [ {
        "x" : 2962,
        "y" : 997
      } ]
    }, {
      "id" : 108501,
      "points" : [ {
        "x" : 2959,
        "y" : 955
      } ]
    } ],
    "catalysts" : [ {
      "id" : 108503,
      "points" : [ {
        "x" : 2802,
        "y" : 1006
      } ]
    } ]
  }, {
    "id" : 108509,
    "reactomeId" : 10926929,
    "displayName" : "Isomerization of 25(R) DHCA-CoA to 25(S) DHCA-CoA",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 3195,
      "y" : 937
    },
    "minX" : 3152,
    "maxX" : 3224,
    "minY" : 899,
    "maxY" : 943,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 3152,
        "y" : 899
      },
      "to" : {
        "x" : 3195,
        "y" : 937
      }
    }, {
      "from" : {
        "x" : 3195,
        "y" : 937
      },
      "to" : {
        "x" : 3224,
        "y" : 938
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 3217,
        "y" : 942
      },
      "b" : {
        "x" : 3224,
        "y" : 938
      },
      "c" : {
        "x" : 3217,
        "y" : 934
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 3217,
        "y" : 934
      }
    },
    "reactionShape" : {
      "a" : {
        "x" : 3189,
        "y" : 931
      },
      "b" : {
        "x" : 3201,
        "y" : 943
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 3195,
        "y" : 937
      }
    },
    "inputs" : [ {
      "id" : 108510
    } ],
    "outputs" : [ {
      "id" : 108511
    } ],
    "catalysts" : [ {
      "id" : 108508,
      "points" : [ {
        "x" : 3212,
        "y" : 796
      } ]
    } ]
  }, {
    "id" : 108573,
    "reactomeId" : 10926942,
    "displayName" : "3,7,24THCA is conjugated with Coenzyme A (SLC27A5 BACS)",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 2789,
      "y" : 631
    },
    "minX" : 2664,
    "maxX" : 2807,
    "minY" : 625,
    "maxY" : 637,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 2664,
        "y" : 633
      },
      "to" : {
        "x" : 2789,
        "y" : 631
      }
    }, {
      "from" : {
        "x" : 2789,
        "y" : 631
      },
      "to" : {
        "x" : 2807,
        "y" : 634
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 2783,
        "y" : 625
      },
      "b" : {
        "x" : 2795,
        "y" : 637
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 2789,
        "y" : 631
      }
    },
    "inputs" : [ {
      "id" : 108574,
      "points" : [ {
        "x" : 2568,
        "y" : 451
      } ]
    }, {
      "id" : 108567,
      "points" : [ {
        "x" : 2644,
        "y" : 537
      } ]
    }, {
      "id" : 108565,
      "points" : [ {
        "x" : 2571,
        "y" : 538
      } ]
    } ],
    "outputs" : [ {
      "id" : 108575,
      "points" : [ {
        "x" : 2927,
        "y" : 612
      } ]
    }, {
      "id" : 108571,
      "points" : [ {
        "x" : 2962,
        "y" : 537
      } ]
    }, {
      "id" : 108570,
      "points" : [ {
        "x" : 2879,
        "y" : 538
      } ]
    }, {
      "id" : 108569,
      "points" : [ {
        "x" : 2839,
        "y" : 538
      } ]
    } ],
    "catalysts" : [ {
      "id" : 108572,
      "points" : [ {
        "x" : 2780,
        "y" : 502
      } ]
    } ]
  }, {
    "id" : 108639,
    "reactomeId" : 10922703,
    "displayName" : "Cytosolic chenodeoxycholoyl-CoA or choloyl-CoA are conjugated with glycine or taurine",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 4530,
      "y" : 1262
    },
    "minX" : 4524,
    "maxX" : 4536,
    "minY" : 1221,
    "maxY" : 1301,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 4530,
        "y" : 1301
      },
      "to" : {
        "x" : 4530,
        "y" : 1262
      }
    }, {
      "from" : {
        "x" : 4530,
        "y" : 1262
      },
      "to" : {
        "x" : 4530,
        "y" : 1221
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 4524,
        "y" : 1256
      },
      "b" : {
        "x" : 4536,
        "y" : 1268
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 4530,
        "y" : 1262
      }
    },
    "inputs" : [ {
      "id" : 108640,
      "points" : [ {
        "x" : 4545,
        "y" : 1304
      } ]
    }, {
      "id" : 108635,
      "points" : [ {
        "x" : 4530,
        "y" : 1328
      } ]
    } ],
    "outputs" : [ {
      "id" : 108641,
      "points" : [ {
        "x" : 4567,
        "y" : 1223
      } ]
    }, {
      "id" : 108642,
      "points" : [ {
        "x" : 4689,
        "y" : 994
      }, {
        "x" : 4645,
        "y" : 1181
      } ]
    } ],
    "catalysts" : [ {
      "id" : 108643,
      "points" : [ {
        "x" : 4500,
        "y" : 1261
      } ]
    } ]
  }, {
    "id" : 108576,
    "reactomeId" : 10926944,
    "displayName" : "TetraHCA is conjugated with Coenzyme A (SLC27A2 VLCS)",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 2699,
      "y" : 656
    },
    "minX" : 2653,
    "maxX" : 2855,
    "minY" : 650,
    "maxY" : 662,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 2653,
        "y" : 655
      },
      "to" : {
        "x" : 2699,
        "y" : 656
      }
    }, {
      "from" : {
        "x" : 2699,
        "y" : 656
      },
      "to" : {
        "x" : 2855,
        "y" : 656
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 2693,
        "y" : 650
      },
      "b" : {
        "x" : 2705,
        "y" : 662
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 2699,
        "y" : 656
      }
    },
    "inputs" : [ {
      "id" : 108566,
      "points" : [ {
        "x" : 2595,
        "y" : 631
      } ]
    }, {
      "id" : 108567,
      "points" : [ {
        "x" : 2643,
        "y" : 537
      } ]
    }, {
      "id" : 108565,
      "points" : [ {
        "x" : 2567,
        "y" : 538
      } ]
    } ],
    "outputs" : [ {
      "id" : 108568,
      "points" : [ {
        "x" : 2960,
        "y" : 470
      } ]
    }, {
      "id" : 108570,
      "points" : [ {
        "x" : 2886,
        "y" : 538
      } ]
    }, {
      "id" : 108571,
      "points" : [ {
        "x" : 2966,
        "y" : 546
      } ]
    }, {
      "id" : 108569,
      "points" : [ {
        "x" : 2845,
        "y" : 538
      } ]
    } ],
    "catalysts" : [ {
      "id" : 108577,
      "points" : [ {
        "x" : 2702,
        "y" : 566
      } ]
    } ]
  }, {
    "id" : 108512,
    "reactomeId" : 10926813,
    "displayName" : "25(S) THCA-CoA is dehydrogenated to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA (THCA-CoA)",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 3387,
      "y" : 1043
    },
    "minX" : 3335,
    "maxX" : 3446,
    "minY" : 1037,
    "maxY" : 1049,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 3335,
        "y" : 1043
      },
      "to" : {
        "x" : 3387,
        "y" : 1043
      }
    }, {
      "from" : {
        "x" : 3387,
        "y" : 1043
      },
      "to" : {
        "x" : 3446,
        "y" : 1043
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 3381,
        "y" : 1037
      },
      "b" : {
        "x" : 3393,
        "y" : 1049
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 3387,
        "y" : 1043
      }
    },
    "inputs" : [ {
      "id" : 108513,
      "points" : [ {
        "x" : 3304,
        "y" : 1007
      } ]
    }, {
      "id" : 108507,
      "points" : [ {
        "x" : 3315,
        "y" : 1062
      } ]
    } ],
    "outputs" : [ {
      "id" : 108514,
      "points" : [ {
        "x" : 3470,
        "y" : 1008
      } ]
    }, {
      "id" : 108515,
      "points" : [ {
        "x" : 3500,
        "y" : 1044
      } ]
    } ],
    "catalysts" : [ {
      "id" : 108516,
      "points" : [ {
        "x" : 3387,
        "y" : 1003
      } ]
    } ]
  }, {
    "id" : 108579,
    "reactomeId" : 10926956,
    "displayName" : "Isomerization of 25(R) TetraHCA-CoA to (24R, 25R) 3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestanoyl-CoA",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 3218,
      "y" : 460
    },
    "minX" : 3192,
    "maxX" : 3760,
    "minY" : 454,
    "maxY" : 1023,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 3192,
        "y" : 460
      },
      "to" : {
        "x" : 3218,
        "y" : 460
      }
    }, {
      "from" : {
        "x" : 3218,
        "y" : 460
      },
      "to" : {
        "x" : 3641,
        "y" : 460
      }
    }, {
      "from" : {
        "x" : 3641,
        "y" : 460
      },
      "to" : {
        "x" : 3642,
        "y" : 913
      }
    }, {
      "from" : {
        "x" : 3642,
        "y" : 913
      },
      "to" : {
        "x" : 3755,
        "y" : 953
      }
    }, {
      "from" : {
        "x" : 3755,
        "y" : 953
      },
      "to" : {
        "x" : 3760,
        "y" : 1023
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 3756,
        "y" : 1016
      },
      "b" : {
        "x" : 3760,
        "y" : 1023
      },
      "c" : {
        "x" : 3763,
        "y" : 1016
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 3763,
        "y" : 1016
      }
    },
    "reactionShape" : {
      "a" : {
        "x" : 3212,
        "y" : 454
      },
      "b" : {
        "x" : 3224,
        "y" : 466
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 3218,
        "y" : 460
      }
    },
    "inputs" : [ {
      "id" : 108580
    } ],
    "outputs" : [ {
      "id" : 108521
    } ],
    "catalysts" : [ {
      "id" : 108508,
      "points" : [ {
        "x" : 3214,
        "y" : 767
      } ]
    } ]
  }, {
    "id" : 108578,
    "reactomeId" : 10926948,
    "displayName" : "3,7,24THCA is conjugated with Coenzyme A (SLC27A2 VLCS)",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 2703,
      "y" : 393
    },
    "minX" : 2646,
    "maxX" : 2815,
    "minY" : 387,
    "maxY" : 399,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 2646,
        "y" : 395
      },
      "to" : {
        "x" : 2703,
        "y" : 393
      }
    }, {
      "from" : {
        "x" : 2703,
        "y" : 393
      },
      "to" : {
        "x" : 2815,
        "y" : 391
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 2697,
        "y" : 387
      },
      "b" : {
        "x" : 2709,
        "y" : 399
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 2703,
        "y" : 393
      }
    },
    "inputs" : [ {
      "id" : 108574,
      "points" : [ {
        "x" : 2596,
        "y" : 414
      } ]
    }, {
      "id" : 108567,
      "points" : [ {
        "x" : 2642,
        "y" : 500
      } ]
    }, {
      "id" : 108565,
      "points" : [ {
        "x" : 2568,
        "y" : 501
      } ]
    } ],
    "outputs" : [ {
      "id" : 108575,
      "points" : [ {
        "x" : 2964,
        "y" : 581
      } ]
    }, {
      "id" : 108570,
      "points" : [ {
        "x" : 2881,
        "y" : 501
      } ]
    }, {
      "id" : 108571,
      "points" : [ {
        "x" : 2962,
        "y" : 513
      } ]
    }, {
      "id" : 108569,
      "points" : [ {
        "x" : 2840,
        "y" : 501
      } ]
    } ],
    "catalysts" : [ {
      "id" : 108577,
      "points" : [ {
        "x" : 2703,
        "y" : 537
      } ]
    } ]
  }, {
    "id" : 108581,
    "reactomeId" : 10926946,
    "displayName" : "Isomerization of 3,7,24THCA-CoA to (24R, 25R) 3alpha,7alpha,24-trihydroxy-5beta-cholestanoyl-CoA",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 3250,
      "y" : 648
    },
    "minX" : 3244,
    "maxX" : 3304,
    "minY" : 611,
    "maxY" : 654,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 3262,
        "y" : 611
      },
      "to" : {
        "x" : 3250,
        "y" : 648
      }
    }, {
      "from" : {
        "x" : 3250,
        "y" : 648
      },
      "to" : {
        "x" : 3304,
        "y" : 649
      }
    }, {
      "from" : {
        "x" : 3304,
        "y" : 649
      },
      "to" : {
        "x" : 3282,
        "y" : 611
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 3289,
        "y" : 615
      },
      "b" : {
        "x" : 3282,
        "y" : 611
      },
      "c" : {
        "x" : 3282,
        "y" : 619
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 3282,
        "y" : 619
      }
    },
    "reactionShape" : {
      "a" : {
        "x" : 3244,
        "y" : 642
      },
      "b" : {
        "x" : 3256,
        "y" : 654
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 3250,
        "y" : 648
      }
    },
    "inputs" : [ {
      "id" : 108582
    } ],
    "outputs" : [ {
      "id" : 108582
    } ],
    "catalysts" : [ {
      "id" : 108508,
      "points" : [ {
        "x" : 3217,
        "y" : 767
      } ]
    } ]
  }, {
    "id" : 108517,
    "reactomeId" : 10926906,
    "displayName" : "25(S) DHCA-CoA is dehydrogenated to 25(S) 3alpha,7alpha-dihydroxy-5beta-cholest-24-enoyl-CoA",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 3391,
      "y" : 941
    },
    "minX" : 3349,
    "maxX" : 3444,
    "minY" : 935,
    "maxY" : 947,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 3349,
        "y" : 941
      },
      "to" : {
        "x" : 3391,
        "y" : 941
      }
    }, {
      "from" : {
        "x" : 3391,
        "y" : 941
      },
      "to" : {
        "x" : 3444,
        "y" : 942
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 3385,
        "y" : 935
      },
      "b" : {
        "x" : 3397,
        "y" : 947
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 3391,
        "y" : 941
      }
    },
    "inputs" : [ {
      "id" : 108511,
      "points" : [ {
        "x" : 3342,
        "y" : 941
      } ]
    }, {
      "id" : 108513,
      "points" : [ {
        "x" : 3313,
        "y" : 973
      } ]
    } ],
    "outputs" : [ {
      "id" : 108514,
      "points" : [ {
        "x" : 3468,
        "y" : 971
      } ]
    }, {
      "id" : 108518,
      "points" : [ {
        "x" : 3479,
        "y" : 926
      } ]
    } ],
    "catalysts" : [ {
      "id" : 108516,
      "points" : [ {
        "x" : 3388,
        "y" : 974
      } ]
    } ]
  }, {
    "id" : 108644,
    "reactomeId" : 10964911,
    "displayName" : "NR1H4 binds DCA, CDCA, LCHA",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 5479,
      "y" : 1042
    },
    "minX" : 5473,
    "maxX" : 5527,
    "minY" : 1036,
    "maxY" : 1048,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 5479,
        "y" : 1043
      },
      "to" : {
        "x" : 5479,
        "y" : 1042
      }
    }, {
      "from" : {
        "x" : 5479,
        "y" : 1042
      },
      "to" : {
        "x" : 5527,
        "y" : 1042
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 5520,
        "y" : 1046
      },
      "b" : {
        "x" : 5527,
        "y" : 1042
      },
      "c" : {
        "x" : 5520,
        "y" : 1038
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 5520,
        "y" : 1038
      }
    },
    "reactionShape" : {
      "a" : {
        "x" : 5473,
        "y" : 1036
      },
      "b" : {
        "x" : 5485,
        "y" : 1048
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 5479,
        "y" : 1042
      }
    },
    "inputs" : [ {
      "id" : 108645,
      "points" : [ {
        "x" : 5443,
        "y" : 1026
      } ]
    }, {
      "id" : 108646,
      "points" : [ {
        "x" : 5445,
        "y" : 1070
      } ]
    } ],
    "outputs" : [ {
      "id" : 108647
    } ],
    "catalysts" : [ {
      "id" : 108645,
      "points" : [ {
        "x" : 5443,
        "y" : 1013
      }, {
        "x" : 5476,
        "y" : 1009
      } ]
    } ]
  }, {
    "id" : 108583,
    "reactomeId" : 10926964,
    "displayName" : "4-cholesten-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,27-triol-3-one",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 994,
      "y" : 1179
    },
    "minX" : 955,
    "maxX" : 1030,
    "minY" : 1173,
    "maxY" : 1185,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 955,
        "y" : 1179
      },
      "to" : {
        "x" : 994,
        "y" : 1179
      }
    }, {
      "from" : {
        "x" : 994,
        "y" : 1179
      },
      "to" : {
        "x" : 1030,
        "y" : 1178
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 988,
        "y" : 1173
      },
      "b" : {
        "x" : 1000,
        "y" : 1185
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 994,
        "y" : 1179
      }
    },
    "inputs" : [ {
      "id" : 108584,
      "points" : [ {
        "x" : 760,
        "y" : 1144
      } ]
    }, {
      "id" : 108585,
      "points" : [ {
        "x" : 940,
        "y" : 1221
      } ]
    }, {
      "id" : 108586,
      "points" : [ {
        "x" : 901,
        "y" : 1221
      } ]
    } ],
    "outputs" : [ {
      "id" : 108587,
      "points" : [ {
        "x" : 1054,
        "y" : 1177
      } ]
    }, {
      "id" : 108588,
      "points" : [ {
        "x" : 1067,
        "y" : 1220
      } ]
    } ],
    "catalysts" : [ {
      "id" : 108589,
      "points" : [ {
        "x" : 993,
        "y" : 1224
      } ]
    } ]
  }, {
    "id" : 108519,
    "reactomeId" : 10926776,
    "displayName" : "3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA (THCA-CoA) is hydrated to (24R, 25R) 3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestanoyl-CoA",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 3642,
      "y" : 1040
    },
    "minX" : 3618,
    "maxX" : 3695,
    "minY" : 1034,
    "maxY" : 1050,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 3618,
        "y" : 1040
      },
      "to" : {
        "x" : 3642,
        "y" : 1040
      }
    }, {
      "from" : {
        "x" : 3642,
        "y" : 1040
      },
      "to" : {
        "x" : 3695,
        "y" : 1050
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 3687,
        "y" : 1053
      },
      "b" : {
        "x" : 3695,
        "y" : 1050
      },
      "c" : {
        "x" : 3689,
        "y" : 1045
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 3689,
        "y" : 1045
      }
    },
    "reactionShape" : {
      "a" : {
        "x" : 3636,
        "y" : 1034
      },
      "b" : {
        "x" : 3648,
        "y" : 1046
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 3642,
        "y" : 1040
      }
    },
    "inputs" : [ {
      "id" : 108520,
      "points" : [ {
        "x" : 3604,
        "y" : 1008
      } ]
    }, {
      "id" : 108515,
      "points" : [ {
        "x" : 3583,
        "y" : 1042
      } ]
    } ],
    "outputs" : [ {
      "id" : 108521
    } ],
    "catalysts" : [ {
      "id" : 108522,
      "points" : [ {
        "x" : 3674,
        "y" : 1006
      } ]
    } ]
  }, {
    "id" : 108648,
    "reactomeId" : 10982547,
    "displayName" : "STARD5 binds DCA, LCA",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 4259,
      "y" : 1625
    },
    "minX" : 4220,
    "maxX" : 4309,
    "minY" : 1619,
    "maxY" : 1631,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 4220,
        "y" : 1625
      },
      "to" : {
        "x" : 4259,
        "y" : 1625
      }
    }, {
      "from" : {
        "x" : 4259,
        "y" : 1625
      },
      "to" : {
        "x" : 4309,
        "y" : 1623
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 4302,
        "y" : 1627
      },
      "b" : {
        "x" : 4309,
        "y" : 1623
      },
      "c" : {
        "x" : 4302,
        "y" : 1619
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 4302,
        "y" : 1619
      }
    },
    "reactionShape" : {
      "a" : {
        "x" : 4253,
        "y" : 1619
      },
      "b" : {
        "x" : 4265,
        "y" : 1631
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 4259,
        "y" : 1625
      }
    },
    "inputs" : [ {
      "id" : 108649,
      "points" : [ {
        "x" : 4181,
        "y" : 1625
      } ]
    }, {
      "id" : 108650,
      "points" : [ {
        "x" : 4175,
        "y" : 1608
      } ]
    } ],
    "outputs" : [ {
      "id" : 108651
    } ],
    "catalysts" : [ {
      "id" : 108649,
      "points" : [ {
        "x" : 4181,
        "y" : 1632
      }, {
        "x" : 4258,
        "y" : 1655
      } ]
    } ]
  }, {
    "id" : 108523,
    "reactomeId" : 10926938,
    "displayName" : "25(S) 3alpha,7alpha-dihydroxy-5beta-cholest-24-enoyl-CoA is hydrated to (24R, 25R) 3alpha,7alpha,24-trihydroxy-5beta-cholestanoyl-CoA",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 3642,
      "y" : 941
    },
    "minX" : 3618,
    "maxX" : 3703,
    "minY" : 924,
    "maxY" : 947,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 3618,
        "y" : 940
      },
      "to" : {
        "x" : 3642,
        "y" : 941
      }
    }, {
      "from" : {
        "x" : 3642,
        "y" : 941
      },
      "to" : {
        "x" : 3703,
        "y" : 924
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 3697,
        "y" : 930
      },
      "b" : {
        "x" : 3703,
        "y" : 924
      },
      "c" : {
        "x" : 3695,
        "y" : 922
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 3695,
        "y" : 922
      }
    },
    "reactionShape" : {
      "a" : {
        "x" : 3636,
        "y" : 935
      },
      "b" : {
        "x" : 3648,
        "y" : 947
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 3642,
        "y" : 941
      }
    },
    "inputs" : [ {
      "id" : 108518,
      "points" : [ {
        "x" : 3586,
        "y" : 926
      } ]
    }, {
      "id" : 108520,
      "points" : [ {
        "x" : 3605,
        "y" : 971
      } ]
    } ],
    "outputs" : [ {
      "id" : 108524
    } ],
    "catalysts" : [ {
      "id" : 108522,
      "points" : [ {
        "x" : 3675,
        "y" : 977
      } ]
    } ]
  }, {
    "id" : 108525,
    "reactomeId" : 10926932,
    "displayName" : "(24R, 25R) 3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestanoyl-CoA is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-one-CoA",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 3882,
      "y" : 1040
    },
    "minX" : 3851,
    "maxX" : 3899,
    "minY" : 1034,
    "maxY" : 1046,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 3851,
        "y" : 1043
      },
      "to" : {
        "x" : 3882,
        "y" : 1040
      }
    }, {
      "from" : {
        "x" : 3882,
        "y" : 1040
      },
      "to" : {
        "x" : 3899,
        "y" : 1039
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 3876,
        "y" : 1034
      },
      "b" : {
        "x" : 3888,
        "y" : 1046
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 3882,
        "y" : 1040
      }
    },
    "inputs" : [ {
      "id" : 108526,
      "points" : [ {
        "x" : 3835,
        "y" : 1008
      } ]
    }, {
      "id" : 108521,
      "points" : [ {
        "x" : 3834,
        "y" : 1047
      } ]
    } ],
    "outputs" : [ {
      "id" : 108527,
      "points" : [ {
        "x" : 3899,
        "y" : 1007
      } ]
    }, {
      "id" : 108528,
      "points" : [ {
        "x" : 3937,
        "y" : 1039
      } ]
    }, {
      "id" : 108529,
      "points" : [ {
        "x" : 3935,
        "y" : 1007
      } ]
    } ],
    "catalysts" : [ {
      "id" : 108522,
      "points" : [ {
        "x" : 3731,
        "y" : 1006
      } ]
    } ]
  }, {
    "id" : 108652,
    "reactomeId" : 10981724,
    "displayName" : "OSBPs transport 25OH-CHOL from ER membrane to plasma membrane",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 321,
      "y" : 981
    },
    "minX" : 293,
    "maxX" : 364,
    "minY" : 975,
    "maxY" : 987,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 293,
        "y" : 981
      },
      "to" : {
        "x" : 321,
        "y" : 981
      }
    }, {
      "from" : {
        "x" : 321,
        "y" : 981
      },
      "to" : {
        "x" : 364,
        "y" : 981
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 357,
        "y" : 985
      },
      "b" : {
        "x" : 364,
        "y" : 981
      },
      "c" : {
        "x" : 357,
        "y" : 977
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 357,
        "y" : 977
      }
    },
    "reactionShape" : {
      "a" : {
        "x" : 315,
        "y" : 975
      },
      "b" : {
        "x" : 327,
        "y" : 987
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 321,
        "y" : 981
      }
    },
    "inputs" : [ {
      "id" : 108653
    } ],
    "outputs" : [ {
      "id" : 108654
    } ],
    "catalysts" : [ {
      "id" : 108655,
      "points" : [ {
        "x" : 320,
        "y" : 1007
      } ]
    } ]
  }, {
    "id" : 108590,
    "reactomeId" : 10926966,
    "displayName" : "4-cholesten-7alpha,27-diol-3-one is reduced to 5beta-cholestan-7alpha,27-diol-3-one",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 995,
      "y" : 1309
    },
    "minX" : 950,
    "maxX" : 1020,
    "minY" : 1303,
    "maxY" : 1315,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 950,
        "y" : 1309
      },
      "to" : {
        "x" : 995,
        "y" : 1309
      }
    }, {
      "from" : {
        "x" : 995,
        "y" : 1309
      },
      "to" : {
        "x" : 1020,
        "y" : 1309
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 989,
        "y" : 1303
      },
      "b" : {
        "x" : 1001,
        "y" : 1315
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 995,
        "y" : 1309
      }
    },
    "inputs" : [ {
      "id" : 108591,
      "points" : [ {
        "x" : 762,
        "y" : 1312
      } ]
    }, {
      "id" : 108585,
      "points" : [ {
        "x" : 938,
        "y" : 1258
      } ]
    }, {
      "id" : 108586,
      "points" : [ {
        "x" : 897,
        "y" : 1258
      } ]
    } ],
    "outputs" : [ {
      "id" : 108592,
      "points" : [ {
        "x" : 1041,
        "y" : 1309
      } ]
    }, {
      "id" : 108588,
      "points" : [ {
        "x" : 1067,
        "y" : 1257
      } ]
    } ],
    "catalysts" : [ {
      "id" : 108589,
      "points" : [ {
        "x" : 993,
        "y" : 1253
      } ]
    } ]
  }, {
    "id" : 108593,
    "reactomeId" : 10926962,
    "displayName" : "5Beta-cholestan-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,27-tetrol",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 1260,
      "y" : 1177
    },
    "minX" : 1213,
    "maxX" : 1278,
    "minY" : 1171,
    "maxY" : 1183,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 1213,
        "y" : 1178
      },
      "to" : {
        "x" : 1260,
        "y" : 1177
      }
    }, {
      "from" : {
        "x" : 1260,
        "y" : 1177
      },
      "to" : {
        "x" : 1278,
        "y" : 1177
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 1254,
        "y" : 1171
      },
      "b" : {
        "x" : 1266,
        "y" : 1183
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 1260,
        "y" : 1177
      }
    },
    "inputs" : [ {
      "id" : 108587,
      "points" : [ {
        "x" : 1193,
        "y" : 1177
      } ]
    }, {
      "id" : 108594,
      "points" : [ {
        "x" : 1198,
        "y" : 1221
      } ]
    }, {
      "id" : 108595,
      "points" : [ {
        "x" : 1162,
        "y" : 1219
      } ]
    } ],
    "outputs" : [ {
      "id" : 108596,
      "points" : [ {
        "x" : 1307,
        "y" : 1174
      } ]
    }, {
      "id" : 108597,
      "points" : [ {
        "x" : 1328,
        "y" : 1216
      } ]
    } ],
    "catalysts" : [ {
      "id" : 108598,
      "points" : [ {
        "x" : 1260,
        "y" : 1208
      } ]
    } ]
  }, {
    "id" : 108656,
    "reactomeId" : 10981845,
    "displayName" : "OSBP exchanges 25OH-CHOL with PI4P from ER membrane to Golgi membrane",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 246,
      "y" : 1100
    },
    "minX" : 240,
    "maxX" : 252,
    "minY" : 1094,
    "maxY" : 1106,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 246,
        "y" : 1102
      },
      "to" : {
        "x" : 246,
        "y" : 1100
      }
    }, {
      "from" : {
        "x" : 246,
        "y" : 1100
      },
      "to" : {
        "x" : 246,
        "y" : 1099
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 240,
        "y" : 1094
      },
      "b" : {
        "x" : 252,
        "y" : 1106
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 246,
        "y" : 1100
      }
    },
    "inputs" : [ {
      "id" : 108657,
      "points" : [ {
        "x" : 193,
        "y" : 1119
      } ]
    }, {
      "id" : 108653,
      "points" : [ {
        "x" : 246,
        "y" : 1000
      } ]
    } ],
    "outputs" : [ {
      "id" : 108658,
      "points" : [ {
        "x" : 246,
        "y" : 1135
      } ]
    }, {
      "id" : 108659,
      "points" : [ {
        "x" : 198,
        "y" : 1069
      } ]
    } ],
    "catalysts" : [ {
      "id" : 108660,
      "points" : [ {
        "x" : 287,
        "y" : 1100
      } ]
    } ]
  }, {
    "id" : 108530,
    "reactomeId" : 10926936,
    "displayName" : "(24R, 25R) 3alpha,7alpha,24-trihydroxy-5beta-cholestanoyl-CoA is oxidized to 3alpha,7alpha-dihydroxy-5beta-cholest-24-one-CoA",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 3879,
      "y" : 947
    },
    "minX" : 3840,
    "maxX" : 3907,
    "minY" : 932,
    "maxY" : 953,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 3840,
        "y" : 932
      },
      "to" : {
        "x" : 3879,
        "y" : 947
      }
    }, {
      "from" : {
        "x" : 3879,
        "y" : 947
      },
      "to" : {
        "x" : 3907,
        "y" : 949
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 3873,
        "y" : 941
      },
      "b" : {
        "x" : 3885,
        "y" : 953
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 3879,
        "y" : 947
      }
    },
    "inputs" : [ {
      "id" : 108526,
      "points" : [ {
        "x" : 3831,
        "y" : 971
      } ]
    }, {
      "id" : 108524,
      "points" : [ {
        "x" : 3815,
        "y" : 928
      } ]
    } ],
    "outputs" : [ {
      "id" : 108527,
      "points" : [ {
        "x" : 3902,
        "y" : 970
      } ]
    }, {
      "id" : 108529,
      "points" : [ {
        "x" : 3933,
        "y" : 970
      } ]
    }, {
      "id" : 108531,
      "points" : [ {
        "x" : 3936,
        "y" : 942
      } ]
    } ],
    "catalysts" : [ {
      "id" : 108522,
      "points" : [ {
        "x" : 3735,
        "y" : 977
      } ]
    } ]
  }, {
    "id" : 108661,
    "reactomeId" : 10988959,
    "displayName" : "Bile salts bind FABP6",
    "schemaClass" : "BlackBoxEvent",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 5106,
      "y" : 1118
    },
    "minX" : 5100,
    "maxX" : 5112,
    "minY" : 1073,
    "maxY" : 1124,
    "reactionType" : "omitted",
    "segments" : [ {
      "from" : {
        "x" : 5104,
        "y" : 1118
      },
      "to" : {
        "x" : 5106,
        "y" : 1118
      }
    }, {
      "from" : {
        "x" : 5106,
        "y" : 1118
      },
      "to" : {
        "x" : 5104,
        "y" : 1073
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 5108,
        "y" : 1080
      },
      "b" : {
        "x" : 5104,
        "y" : 1073
      },
      "c" : {
        "x" : 5100,
        "y" : 1080
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 5100,
        "y" : 1080
      }
    },
    "reactionShape" : {
      "a" : {
        "x" : 5100,
        "y" : 1112
      },
      "b" : {
        "x" : 5112,
        "y" : 1124
      },
      "s" : "\\\\",
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 5106,
        "y" : 1118
      }
    },
    "inputs" : [ {
      "id" : 108662,
      "points" : [ {
        "x" : 5021,
        "y" : 1066
      } ]
    }, {
      "id" : 108614,
      "points" : [ {
        "x" : 5213,
        "y" : 1070
      } ]
    } ],
    "outputs" : [ {
      "id" : 108663
    } ]
  }, {
    "id" : 108532,
    "reactomeId" : 10926914,
    "displayName" : "Hydrolysis of choloyl-CoA to cholate and CoASH",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 4456,
      "y" : 1129
    },
    "minX" : 4433,
    "maxX" : 4491,
    "minY" : 1123,
    "maxY" : 1135,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 4433,
        "y" : 1129
      },
      "to" : {
        "x" : 4456,
        "y" : 1129
      }
    }, {
      "from" : {
        "x" : 4456,
        "y" : 1129
      },
      "to" : {
        "x" : 4491,
        "y" : 1129
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 4450,
        "y" : 1123
      },
      "b" : {
        "x" : 4462,
        "y" : 1135
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 4456,
        "y" : 1129
      }
    },
    "inputs" : [ {
      "id" : 108533,
      "points" : [ {
        "x" : 4421,
        "y" : 1135
      } ]
    }, {
      "id" : 108534,
      "points" : [ {
        "x" : 4296,
        "y" : 1083
      } ]
    } ],
    "outputs" : [ {
      "id" : 108535,
      "points" : [ {
        "x" : 4512,
        "y" : 1136
      } ]
    }, {
      "id" : 108536,
      "points" : [ {
        "x" : 4528,
        "y" : 1104
      } ]
    } ],
    "catalysts" : [ {
      "id" : 108537,
      "points" : [ {
        "x" : 4455,
        "y" : 1096
      } ]
    } ]
  }, {
    "id" : 108599,
    "reactomeId" : 10926968,
    "displayName" : "5beta-cholestan-7alpha,27-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,27-triol",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 1260,
      "y" : 1309
    },
    "minX" : 1207,
    "maxX" : 1278,
    "minY" : 1303,
    "maxY" : 1315,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 1207,
        "y" : 1309
      },
      "to" : {
        "x" : 1260,
        "y" : 1309
      }
    }, {
      "from" : {
        "x" : 1260,
        "y" : 1309
      },
      "to" : {
        "x" : 1278,
        "y" : 1308
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 1254,
        "y" : 1303
      },
      "b" : {
        "x" : 1266,
        "y" : 1315
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 1260,
        "y" : 1309
      }
    },
    "inputs" : [ {
      "id" : 108592,
      "points" : [ {
        "x" : 1186,
        "y" : 1309
      } ]
    }, {
      "id" : 108595,
      "points" : [ {
        "x" : 1157,
        "y" : 1256
      } ]
    }, {
      "id" : 108594,
      "points" : [ {
        "x" : 1196,
        "y" : 1258
      } ]
    } ],
    "outputs" : [ {
      "id" : 108600,
      "points" : [ {
        "x" : 1299,
        "y" : 1309
      } ]
    }, {
      "id" : 108597,
      "points" : [ {
        "x" : 1333,
        "y" : 1253
      } ]
    } ],
    "catalysts" : [ {
      "id" : 108598,
      "points" : [ {
        "x" : 1260,
        "y" : 1262
      } ]
    } ]
  }, {
    "id" : 108473,
    "reactomeId" : 10926749,
    "displayName" : "4-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholesten-7alpha, 12alpha-diol-3-one",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 983,
      "y" : 1037
    },
    "minX" : 935,
    "maxX" : 1001,
    "minY" : 1031,
    "maxY" : 1043,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 935,
        "y" : 1037
      },
      "to" : {
        "x" : 983,
        "y" : 1037
      }
    }, {
      "from" : {
        "x" : 983,
        "y" : 1037
      },
      "to" : {
        "x" : 1001,
        "y" : 1038
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 977,
        "y" : 1031
      },
      "b" : {
        "x" : 989,
        "y" : 1043
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 983,
        "y" : 1037
      }
    },
    "inputs" : [ {
      "id" : 108474,
      "points" : [ {
        "x" : 766,
        "y" : 1065
      } ]
    }, {
      "id" : 108475,
      "points" : [ {
        "x" : 917,
        "y" : 992
      } ]
    }, {
      "id" : 108476,
      "points" : [ {
        "x" : 875,
        "y" : 992
      } ]
    } ],
    "outputs" : [ {
      "id" : 108477,
      "points" : [ {
        "x" : 1054,
        "y" : 1036
      } ]
    }, {
      "id" : 108478,
      "points" : [ {
        "x" : 1060,
        "y" : 990
      } ]
    } ],
    "catalysts" : [ {
      "id" : 108479,
      "points" : [ {
        "x" : 981,
        "y" : 988
      } ]
    } ]
  }, {
    "id" : 108665,
    "reactomeId" : 10927002,
    "displayName" : "ABCC3 transports bile salts from cytosol to extracellular region",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 5236,
      "y" : 1220
    },
    "minX" : 5230,
    "maxX" : 5242,
    "minY" : 1133,
    "maxY" : 1226,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 5236,
        "y" : 1133
      },
      "to" : {
        "x" : 5236,
        "y" : 1220
      }
    }, {
      "from" : {
        "x" : 5236,
        "y" : 1220
      },
      "to" : {
        "x" : 5239,
        "y" : 1220
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 5230,
        "y" : 1214
      },
      "b" : {
        "x" : 5242,
        "y" : 1226
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 5236,
        "y" : 1220
      }
    },
    "inputs" : [ {
      "id" : 108666,
      "points" : [ {
        "x" : 5266,
        "y" : 1114
      } ]
    }, {
      "id" : 108614,
      "points" : [ {
        "x" : 5236,
        "y" : 1070
      } ]
    } ],
    "outputs" : [ {
      "id" : 108667,
      "points" : [ {
        "x" : 5269,
        "y" : 1194
      } ]
    }, {
      "id" : 108617,
      "points" : [ {
        "x" : 5016,
        "y" : 1310
      }, {
        "x" : 5213,
        "y" : 1277
      } ]
    }, {
      "id" : 108668,
      "points" : [ {
        "x" : 5320,
        "y" : 1182
      } ]
    } ],
    "catalysts" : [ {
      "id" : 108669,
      "points" : [ {
        "x" : 5304,
        "y" : 1220
      } ]
    } ]
  }, {
    "id" : 108601,
    "reactomeId" : 10926680,
    "displayName" : "Cholesterol is hydroxylated to 25-hydroxycholesterol",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 289,
      "y" : 845
    },
    "minX" : 283,
    "maxX" : 295,
    "minY" : 808,
    "maxY" : 890,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 289,
        "y" : 890
      },
      "to" : {
        "x" : 289,
        "y" : 845
      }
    }, {
      "from" : {
        "x" : 289,
        "y" : 845
      },
      "to" : {
        "x" : 289,
        "y" : 808
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 283,
        "y" : 839
      },
      "b" : {
        "x" : 295,
        "y" : 851
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 289,
        "y" : 845
      }
    },
    "inputs" : [ {
      "id" : 108602,
      "points" : [ {
        "x" : 251,
        "y" : 906
      } ]
    }, {
      "id" : 108603,
      "points" : [ {
        "x" : 309,
        "y" : 909
      } ]
    }, {
      "id" : 108604,
      "points" : [ {
        "x" : 308,
        "y" : 889
      } ]
    }, {
      "id" : 108605,
      "points" : [ {
        "x" : 282,
        "y" : 915
      } ]
    } ],
    "outputs" : [ {
      "id" : 108606,
      "points" : [ {
        "x" : 268,
        "y" : 805
      } ]
    }, {
      "id" : 108607,
      "points" : [ {
        "x" : 289,
        "y" : 777
      } ]
    }, {
      "id" : 108608,
      "points" : [ {
        "x" : 311,
        "y" : 799
      } ]
    } ],
    "catalysts" : [ {
      "id" : 108609,
      "points" : [ {
        "x" : 263,
        "y" : 845
      } ]
    } ]
  }, {
    "id" : 108664,
    "reactomeId" : 10988957,
    "displayName" : "Bile salts dissociate from FABP6",
    "schemaClass" : "BlackBoxEvent",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 5104,
      "y" : 984
    },
    "minX" : 5098,
    "maxX" : 5110,
    "minY" : 978,
    "maxY" : 1028,
    "reactionType" : "omitted",
    "segments" : [ {
      "from" : {
        "x" : 5104,
        "y" : 1028
      },
      "to" : {
        "x" : 5104,
        "y" : 984
      }
    }, {
      "from" : {
        "x" : 5104,
        "y" : 984
      },
      "to" : {
        "x" : 5107,
        "y" : 989
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 5098,
        "y" : 978
      },
      "b" : {
        "x" : 5110,
        "y" : 990
      },
      "s" : "\\\\",
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 5104,
        "y" : 984
      }
    },
    "inputs" : [ {
      "id" : 108663
    } ],
    "outputs" : [ {
      "id" : 108662,
      "points" : [ {
        "x" : 5023,
        "y" : 1037
      } ]
    }, {
      "id" : 108614,
      "points" : [ {
        "x" : 5212,
        "y" : 1035
      } ]
    } ]
  }, {
    "id" : 108538,
    "reactomeId" : 10926766,
    "displayName" : "Choloyl CoA reacts with glycine or taurine to form glycocholate or taurocholate",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 4383,
      "y" : 1037
    },
    "minX" : 4300,
    "maxX" : 4423,
    "minY" : 1031,
    "maxY" : 1043,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 4300,
        "y" : 1037
      },
      "to" : {
        "x" : 4383,
        "y" : 1037
      }
    }, {
      "from" : {
        "x" : 4383,
        "y" : 1037
      },
      "to" : {
        "x" : 4423,
        "y" : 1037
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 4377,
        "y" : 1031
      },
      "b" : {
        "x" : 4389,
        "y" : 1043
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 4383,
        "y" : 1037
      }
    },
    "inputs" : [ {
      "id" : 108539,
      "points" : [ {
        "x" : 4306,
        "y" : 1004
      } ]
    }, {
      "id" : 108534,
      "points" : [ {
        "x" : 4274,
        "y" : 1052
      } ]
    } ],
    "outputs" : [ {
      "id" : 108540,
      "points" : [ {
        "x" : 4456,
        "y" : 1037
      } ]
    }, {
      "id" : 108541,
      "points" : [ {
        "x" : 4460,
        "y" : 1005
      } ]
    } ],
    "catalysts" : [ {
      "id" : 108542,
      "points" : [ {
        "x" : 4383,
        "y" : 1001
      } ]
    } ]
  }, {
    "id" : 108543,
    "reactomeId" : 10926934,
    "displayName" : "Chenodeoxycholoyl CoA reacts with glycine or taurine to form glycochenodeoxycholate or taurochenodeoxycholate",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 4380,
      "y" : 937
    },
    "minX" : 4297,
    "maxX" : 4422,
    "minY" : 931,
    "maxY" : 943,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 4297,
        "y" : 936
      },
      "to" : {
        "x" : 4380,
        "y" : 937
      }
    }, {
      "from" : {
        "x" : 4380,
        "y" : 937
      },
      "to" : {
        "x" : 4422,
        "y" : 937
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 4374,
        "y" : 931
      },
      "b" : {
        "x" : 4386,
        "y" : 943
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 4380,
        "y" : 937
      }
    },
    "inputs" : [ {
      "id" : 108539,
      "points" : [ {
        "x" : 4306,
        "y" : 969
      } ]
    }, {
      "id" : 108544,
      "points" : [ {
        "x" : 4278,
        "y" : 928
      } ]
    } ],
    "outputs" : [ {
      "id" : 108545,
      "points" : [ {
        "x" : 4474,
        "y" : 919
      } ]
    }, {
      "id" : 108541,
      "points" : [ {
        "x" : 4459,
        "y" : 968
      } ]
    } ],
    "catalysts" : [ {
      "id" : 108542,
      "points" : [ {
        "x" : 4382,
        "y" : 972
      } ]
    } ]
  } ],
  "compartments" : [ {
    "id" : 108673,
    "reactomeId" : 5460,
    "displayName" : "mitochondrial matrix",
    "schemaClass" : "Compartment",
    "renderableClass" : "Compartment",
    "position" : {
      "x" : 1976,
      "y" : 809
    },
    "minX" : 1444,
    "maxX" : 2509,
    "minY" : 273,
    "maxY" : 1346,
    "prop" : {
      "x" : 1444,
      "y" : 273,
      "width" : 1065,
      "height" : 1073
    },
    "textPosition" : {
      "x" : 1837,
      "y" : 1298
    },
    "insets" : {
      "x" : 1454,
      "y" : 283,
      "width" : 1045,
      "height" : 1053
    },
    "bgColor" : {
      "r" : 250,
      "g" : 240,
      "b" : 240
    }
  }, {
    "id" : 108801,
    "reactomeId" : 17963,
    "displayName" : "Golgi lumen",
    "schemaClass" : "Compartment",
    "renderableClass" : "Compartment",
    "position" : {
      "x" : 148,
      "y" : 1190
    },
    "minX" : 40,
    "maxX" : 256,
    "minY" : 1118,
    "maxY" : 1262,
    "prop" : {
      "x" : 40,
      "y" : 1118,
      "width" : 216,
      "height" : 144
    },
    "textPosition" : {
      "x" : 83,
      "y" : 1219
    },
    "insets" : {
      "x" : 50,
      "y" : 1128,
      "width" : 196,
      "height" : 124
    },
    "bgColor" : {
      "r" : 250,
      "g" : 240,
      "b" : 240
    },
    "componentIds" : [ 108658, 108657 ]
  }, {
    "id" : 108672,
    "reactomeId" : 17957,
    "displayName" : "endoplasmic reticulum lumen",
    "schemaClass" : "Compartment",
    "renderableClass" : "Compartment",
    "position" : {
      "x" : 648,
      "y" : 856
    },
    "minX" : 591,
    "maxX" : 706,
    "minY" : 80,
    "maxY" : 1633,
    "prop" : {
      "x" : 591,
      "y" : 80,
      "width" : 115,
      "height" : 1553
    },
    "textPosition" : {
      "x" : 594,
      "y" : 1563
    },
    "insets" : {
      "x" : 601,
      "y" : 90,
      "width" : 95,
      "height" : 1533
    },
    "bgColor" : {
      "r" : 250,
      "g" : 240,
      "b" : 240
    },
    "componentIds" : [ 108481, 108474, 108554, 108547, 108591, 108584 ]
  }, {
    "id" : 108800,
    "reactomeId" : 7660,
    "displayName" : "nucleoplasm",
    "schemaClass" : "Compartment",
    "renderableClass" : "Compartment",
    "position" : {
      "x" : 1045,
      "y" : 1516
    },
    "minX" : 931,
    "maxX" : 1160,
    "minY" : 1449,
    "maxY" : 1583,
    "prop" : {
      "x" : 931,
      "y" : 1449,
      "width" : 229,
      "height" : 134
    },
    "textPosition" : {
      "x" : 989,
      "y" : 1537
    },
    "insets" : {
      "x" : 941,
      "y" : 1459,
      "width" : 209,
      "height" : 114
    },
    "bgColor" : {
      "r" : 250,
      "g" : 240,
      "b" : 240
    }
  }, {
    "id" : 108674,
    "reactomeId" : 17951,
    "displayName" : "peroxisomal matrix",
    "schemaClass" : "Compartment",
    "renderableClass" : "Compartment",
    "position" : {
      "x" : 3846,
      "y" : 724
    },
    "minX" : 3052,
    "maxX" : 4640,
    "minY" : 271,
    "maxY" : 1177,
    "prop" : {
      "x" : 3052,
      "y" : 271,
      "width" : 1588,
      "height" : 906
    },
    "textPosition" : {
      "x" : 3071,
      "y" : 1139
    },
    "insets" : {
      "x" : 3062,
      "y" : 281,
      "width" : 1568,
      "height" : 886
    },
    "bgColor" : {
      "r" : 250,
      "g" : 240,
      "b" : 240
    },
    "componentIds" : [ 108506, 108510, 108508, 108507, 108505, 108511, 108509, 108512, 108514, 108515, 108516, 108513, 108517, 108518, 108519, 108520, 108521, 108522, 108523, 108525, 108526, 108527, 108528, 108529, 108530, 108531, 108534, 108544, 108532, 108533, 108535, 108537, 108536, 108539, 108540, 108542, 108538, 108543, 108545, 108541, 108580, 108582, 108579, 108581, 108524, 108811, 108812 ]
  }, {
    "id" : 108711,
    "reactomeId" : 17957,
    "displayName" : "endoplasmic reticulum lumen",
    "schemaClass" : "Compartment",
    "renderableClass" : "Compartment",
    "position" : {
      "x" : 2757,
      "y" : 985
    },
    "minX" : 2709,
    "maxX" : 2806,
    "minY" : 923,
    "maxY" : 1048,
    "prop" : {
      "x" : 2709,
      "y" : 923,
      "width" : 97,
      "height" : 125
    },
    "textPosition" : {
      "x" : 2708,
      "y" : 948
    },
    "insets" : {
      "x" : 2719,
      "y" : 933,
      "width" : 77,
      "height" : 105
    },
    "bgColor" : {
      "r" : 250,
      "g" : 240,
      "b" : 240
    },
    "componentIds" : [ 108499, 108502, 108498, 108504, 108503 ]
  }, {
    "id" : 108807,
    "reactomeId" : 7660,
    "displayName" : "nucleoplasm",
    "schemaClass" : "Compartment",
    "renderableClass" : "Compartment",
    "position" : {
      "x" : 5646,
      "y" : 1053
    },
    "minX" : 5360,
    "maxX" : 5932,
    "minY" : 958,
    "maxY" : 1148,
    "prop" : {
      "x" : 5360,
      "y" : 958,
      "width" : 572,
      "height" : 190
    },
    "textPosition" : {
      "x" : 5373,
      "y" : 971
    },
    "insets" : {
      "x" : 5370,
      "y" : 968,
      "width" : 552,
      "height" : 170
    },
    "bgColor" : {
      "r" : 250,
      "g" : 240,
      "b" : 240
    },
    "componentIds" : [ 108644, 108646, 108645, 108647 ]
  }, {
    "id" : 108806,
    "reactomeId" : 70101,
    "displayName" : "cytosol",
    "schemaClass" : "Compartment",
    "renderableClass" : "Compartment",
    "position" : {
      "x" : 5462,
      "y" : 1066
    },
    "minX" : 4967,
    "maxX" : 5958,
    "minY" : 908,
    "maxY" : 1225,
    "prop" : {
      "x" : 4967,
      "y" : 908,
      "width" : 991,
      "height" : 317
    },
    "textPosition" : {
      "x" : 4987,
      "y" : 921
    },
    "insets" : {
      "x" : 4977,
      "y" : 918,
      "width" : 971,
      "height" : 297
    },
    "bgColor" : {
      "r" : 250,
      "g" : 240,
      "b" : 240
    },
    "componentIds" : [ 108610, 108615, 108613, 108662, 108661, 108664, 108665, 108668, 108669, 108807, 108663, 108614, 108667, 108666 ]
  }, {
    "id" : 108717,
    "reactomeId" : 17957,
    "displayName" : "endoplasmic reticulum lumen",
    "schemaClass" : "Compartment",
    "renderableClass" : "Compartment",
    "position" : {
      "x" : 137,
      "y" : 232
    },
    "minX" : 87,
    "maxX" : 188,
    "minY" : 121,
    "maxY" : 344,
    "prop" : {
      "x" : 87,
      "y" : 121,
      "width" : 101,
      "height" : 223
    },
    "textPosition" : {
      "x" : 90,
      "y" : 276
    },
    "insets" : {
      "x" : 97,
      "y" : 131,
      "width" : 81,
      "height" : 203
    },
    "bgColor" : {
      "r" : 250,
      "g" : 240,
      "b" : 240
    }
  }, {
    "id" : 108789,
    "reactomeId" : 5460,
    "displayName" : "mitochondrial matrix",
    "schemaClass" : "Compartment",
    "renderableClass" : "Compartment",
    "position" : {
      "x" : 261,
      "y" : 1478
    },
    "minX" : 138,
    "maxX" : 384,
    "minY" : 1342,
    "maxY" : 1614,
    "prop" : {
      "x" : 138,
      "y" : 1342,
      "width" : 246,
      "height" : 272
    },
    "textPosition" : {
      "x" : 149,
      "y" : 1572
    },
    "insets" : {
      "x" : 148,
      "y" : 1352,
      "width" : 226,
      "height" : 252
    },
    "bgColor" : {
      "r" : 250,
      "g" : 240,
      "b" : 240
    }
  }, {
    "id" : 108765,
    "reactomeId" : 70101,
    "displayName" : "cytosol",
    "schemaClass" : "Compartment",
    "renderableClass" : "Compartment",
    "position" : {
      "x" : 204,
      "y" : 1045
    },
    "minX" : 0,
    "maxX" : 409,
    "minY" : 430,
    "maxY" : 1660,
    "prop" : {
      "x" : 0,
      "y" : 430,
      "width" : 409,
      "height" : 1230
    },
    "textPosition" : {
      "x" : 24,
      "y" : 1363
    },
    "insets" : {
      "x" : 10,
      "y" : 440,
      "width" : 389,
      "height" : 1210
    },
    "bgColor" : {
      "r" : 250,
      "g" : 240,
      "b" : 240
    },
    "componentIds" : [ 108766, 108789, 108605, 108603, 108604, 108606, 108608, 108607, 108601, 108799, 108652, 108655, 108654, 108656, 108801, 108660 ]
  }, {
    "id" : 108764,
    "reactomeId" : 17957,
    "displayName" : "endoplasmic reticulum lumen",
    "schemaClass" : "Compartment",
    "renderableClass" : "Compartment",
    "position" : {
      "x" : 2741,
      "y" : 524
    },
    "minX" : 2676,
    "maxX" : 2806,
    "minY" : 462,
    "maxY" : 586,
    "prop" : {
      "x" : 2676,
      "y" : 462,
      "width" : 130,
      "height" : 124
    },
    "textPosition" : {
      "x" : 2680,
      "y" : 491
    },
    "insets" : {
      "x" : 2686,
      "y" : 472,
      "width" : 110,
      "height" : 104
    },
    "bgColor" : {
      "r" : 250,
      "g" : 240,
      "b" : 240
    },
    "componentIds" : [ 108572, 108577 ]
  }, {
    "id" : 108796,
    "reactomeId" : 17957,
    "displayName" : "endoplasmic reticulum lumen",
    "schemaClass" : "Compartment",
    "renderableClass" : "Compartment",
    "position" : {
      "x" : 4359,
      "y" : 1490
    },
    "minX" : 4307,
    "maxX" : 4411,
    "minY" : 1435,
    "maxY" : 1546,
    "prop" : {
      "x" : 4307,
      "y" : 1435,
      "width" : 104,
      "height" : 111
    },
    "textPosition" : {
      "x" : 4311,
      "y" : 1478
    },
    "insets" : {
      "x" : 4317,
      "y" : 1445,
      "width" : 84,
      "height" : 91
    },
    "bgColor" : {
      "r" : 250,
      "g" : 240,
      "b" : 240
    },
    "componentIds" : [ 108638 ]
  }, {
    "id" : 108671,
    "reactomeId" : 70101,
    "displayName" : "cytosol",
    "schemaClass" : "Compartment",
    "renderableClass" : "Compartment",
    "position" : {
      "x" : 205,
      "y" : 233
    },
    "minX" : 53,
    "maxX" : 358,
    "minY" : 73,
    "maxY" : 394,
    "prop" : {
      "x" : 53,
      "y" : 73,
      "width" : 305,
      "height" : 321
    },
    "textPosition" : {
      "x" : 79,
      "y" : 356
    },
    "insets" : {
      "x" : 63,
      "y" : 83,
      "width" : 285,
      "height" : 301
    },
    "bgColor" : {
      "r" : 250,
      "g" : 240,
      "b" : 240
    },
    "componentIds" : [ 108717 ]
  }, {
    "id" : 108799,
    "reactomeId" : 7660,
    "displayName" : "nucleoplasm",
    "schemaClass" : "Compartment",
    "renderableClass" : "Compartment",
    "position" : {
      "x" : 90,
      "y" : 672
    },
    "minX" : 13,
    "maxX" : 168,
    "minY" : 604,
    "maxY" : 741,
    "prop" : {
      "x" : 13,
      "y" : 604,
      "width" : 155,
      "height" : 137
    },
    "textPosition" : {
      "x" : 47,
      "y" : 617
    },
    "insets" : {
      "x" : 23,
      "y" : 614,
      "width" : 135,
      "height" : 117
    },
    "bgColor" : {
      "r" : 250,
      "g" : 240,
      "b" : 240
    }
  }, {
    "id" : 108670,
    "reactomeId" : 70101,
    "displayName" : "cytosol",
    "schemaClass" : "Compartment",
    "renderableClass" : "Compartment",
    "position" : {
      "x" : 2658,
      "y" : 863
    },
    "minX" : 541,
    "maxX" : 4775,
    "minY" : 45,
    "maxY" : 1681,
    "prop" : {
      "x" : 541,
      "y" : 45,
      "width" : 4234,
      "height" : 1636
    },
    "textPosition" : {
      "x" : 938,
      "y" : 86
    },
    "insets" : {
      "x" : 551,
      "y" : 55,
      "width" : 4214,
      "height" : 1616
    },
    "bgColor" : {
      "r" : 250,
      "g" : 240,
      "b" : 240
    },
    "componentIds" : [ 108672, 108477, 108479, 108478, 108482, 108476, 108475, 108486, 108484, 108485, 108487, 108483, 108490, 108489, 108492, 108500, 108711, 108494, 108493, 108496, 108473, 108480, 108642, 108714, 108550, 108552, 108551, 108546, 108548, 108549, 108553, 108555, 108559, 108556, 108557, 108558, 108560, 108562, 108563, 108566, 108574, 108764, 108567, 108570, 108571, 108565, 108568, 108569, 108673, 108674, 108583, 108589, 108585, 108586, 108587, 108588, 108590, 108592, 108593, 108596, 108594, 108595, 108597, 108600, 108599, 108626, 108628, 108629, 108627, 108630, 108632, 108634, 108635, 108631, 108633, 108636, 108637, 108640, 108641, 108643, 108796, 108497, 108495, 108501, 108491, 108810, 108564, 108578, 108561, 108488, 108598, 108800, 108648, 108649, 108651, 108639, 108624, 108575, 108573, 108576, 108621, 108619, 108616, 108620, 108623, 108622, 108650 ]
  }, {
    "id" : 108766,
    "reactomeId" : 17957,
    "displayName" : "endoplasmic reticulum lumen",
    "schemaClass" : "Compartment",
    "renderableClass" : "Compartment",
    "position" : {
      "x" : 179,
      "y" : 945
    },
    "minX" : 107,
    "maxX" : 252,
    "minY" : 823,
    "maxY" : 1068,
    "prop" : {
      "x" : 107,
      "y" : 823,
      "width" : 145,
      "height" : 245
    },
    "textPosition" : {
      "x" : 120,
      "y" : 912
    },
    "insets" : {
      "x" : 117,
      "y" : 833,
      "width" : 125,
      "height" : 225
    },
    "bgColor" : {
      "r" : 250,
      "g" : 240,
      "b" : 240
    },
    "componentIds" : [ 108609, 108602, 108653, 108659 ]
  } ],
  "notes" : [ {
    "id" : 108803,
    "displayName" : "HEPATOCYTE",
    "renderableClass" : "Note",
    "position" : {
      "x" : 965,
      "y" : 12
    },
    "minX" : 912,
    "maxX" : 1018,
    "minY" : 0,
    "maxY" : 25,
    "prop" : {
      "x" : 912,
      "y" : 0,
      "width" : 106,
      "height" : 25
    },
    "textPosition" : {
      "x" : 921,
      "y" : 2
    },
    "fgColor" : {
      "r" : 0,
      "g" : 0,
      "b" : 255
    }
  }, {
    "id" : 108805,
    "displayName" : "ENTEROCYTE BASOLATERAL MEMBRANE",
    "renderableClass" : "Note",
    "position" : {
      "x" : 5404,
      "y" : 1261
    },
    "minX" : 5342,
    "maxX" : 5467,
    "minY" : 1244,
    "maxY" : 1279,
    "prop" : {
      "x" : 5342,
      "y" : 1244,
      "width" : 125,
      "height" : 35
    },
    "textPosition" : {
      "x" : 5356,
      "y" : 1237
    },
    "fgColor" : {
      "r" : 0,
      "g" : 0,
      "b" : 255
    }
  }, {
    "id" : 108804,
    "displayName" : "ENTEROCYTE APICAL MEMBRANE",
    "renderableClass" : "Note",
    "position" : {
      "x" : 5403,
      "y" : 878
    },
    "minX" : 5341,
    "maxX" : 5466,
    "minY" : 861,
    "maxY" : 896,
    "prop" : {
      "x" : 5341,
      "y" : 861,
      "width" : 125,
      "height" : 35
    },
    "textPosition" : {
      "x" : 5342,
      "y" : 861
    },
    "fgColor" : {
      "r" : 0,
      "g" : 0,
      "b" : 255
    }
  }, {
    "id" : 108809,
    "displayName" : "PORTAL BLOOD SYSTEM",
    "renderableClass" : "Note",
    "position" : {
      "x" : 5173,
      "y" : 1372
    },
    "minX" : 5111,
    "maxX" : 5236,
    "minY" : 1355,
    "maxY" : 1390,
    "prop" : {
      "x" : 5111,
      "y" : 1355,
      "width" : 125,
      "height" : 35
    },
    "textPosition" : {
      "x" : 5122,
      "y" : 1355
    },
    "fgColor" : {
      "r" : 0,
      "g" : 0,
      "b" : 255
    }
  }, {
    "id" : 108808,
    "displayName" : "GALLBLADDER LUMEN",
    "renderableClass" : "Note",
    "position" : {
      "x" : 4870,
      "y" : 826
    },
    "minX" : 4808,
    "maxX" : 4933,
    "minY" : 809,
    "maxY" : 844,
    "prop" : {
      "x" : 4808,
      "y" : 809,
      "width" : 125,
      "height" : 35
    },
    "textPosition" : {
      "x" : 4822,
      "y" : 809
    },
    "fgColor" : {
      "r" : 0,
      "g" : 0,
      "b" : 255
    }
  } ],
  "links" : [ {
    "id" : 108810,
    "renderableClass" : "EntitySetAndMemberLink",
    "position" : {
      "x" : 4251,
      "y" : 1428
    },
    "minX" : 4245,
    "maxX" : 4492,
    "minY" : 1233,
    "maxY" : 1560,
    "segments" : [ {
      "from" : {
        "x" : 4437,
        "y" : 1233
      },
      "to" : {
        "x" : 4251,
        "y" : 1308
      }
    }, {
      "from" : {
        "x" : 4251,
        "y" : 1308
      },
      "to" : {
        "x" : 4251,
        "y" : 1548
      }
    }, {
      "from" : {
        "x" : 4251,
        "y" : 1548
      },
      "to" : {
        "x" : 4492,
        "y" : 1560
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 4245,
        "y" : 1422
      },
      "b" : {
        "x" : 4257,
        "y" : 1434
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 4251,
        "y" : 1428
      }
    },
    "inputs" : [ {
      "id" : 108714
    } ],
    "outputs" : [ {
      "id" : 108632
    } ]
  }, {
    "id" : 108813,
    "renderableClass" : "EntitySetAndEntitySetLink",
    "position" : {
      "x" : 4813,
      "y" : 1418
    },
    "minX" : 4807,
    "maxX" : 4933,
    "minY" : 1338,
    "maxY" : 1533,
    "segments" : [ {
      "from" : {
        "x" : 4861,
        "y" : 1533
      },
      "to" : {
        "x" : 4813,
        "y" : 1418
      }
    }, {
      "from" : {
        "x" : 4813,
        "y" : 1418
      },
      "to" : {
        "x" : 4933,
        "y" : 1338
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 4807,
        "y" : 1412
      },
      "b" : {
        "x" : 4819,
        "y" : 1424
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 4813,
        "y" : 1418
      }
    },
    "inputs" : [ {
      "id" : 108625
    } ],
    "outputs" : [ {
      "id" : 108617
    } ]
  } ],
  "shadows" : [ {
    "id" : 108815,
    "reactomeId" : 10994275,
    "displayName" : "Synthesis of bile acids and bile salts",
    "schemaClass" : "Pathway",
    "renderableClass" : "Shadow",
    "position" : {
      "x" : 2363,
      "y" : 859
    },
    "minX" : 138,
    "maxX" : 4589,
    "minY" : 367,
    "maxY" : 1352,
    "prop" : {
      "x" : 138,
      "y" : 823,
      "width" : 3974,
      "height" : 529
    },
    "points" : [ {
      "x" : 138,
      "y" : 367
    }, {
      "x" : 4589,
      "y" : 367
    }, {
      "x" : 4589,
      "y" : 1352
    }, {
      "x" : 138,
      "y" : 1352
    } ],
    "colour" : "#dc3912"
  }, {
    "id" : 108814,
    "reactomeId" : 10994011,
    "displayName" : "Recycling of bile acids and salts",
    "schemaClass" : "Pathway",
    "renderableClass" : "Shadow",
    "position" : {
      "x" : 4886,
      "y" : 1239
    },
    "minX" : 4112,
    "maxX" : 5661,
    "minY" : 823,
    "maxY" : 1656,
    "prop" : {
      "x" : 4589,
      "y" : 823,
      "width" : 1072,
      "height" : 529
    },
    "points" : [ {
      "x" : 4112,
      "y" : 823
    }, {
      "x" : 5661,
      "y" : 823
    }, {
      "x" : 5661,
      "y" : 1656
    }, {
      "x" : 4112,
      "y" : 1656
    } ],
    "colour" : "#4684ee"
  } ],
  "minX" : 0,
  "maxX" : 5958,
  "minY" : 0,
  "maxY" : 1681,
  "disease" : false
}