{
  "dbId" : 10445540,
  "stId" : "R-BTA-5626467",
  "speciesName" : "Bos taurus",
  "nodes" : [ {
    "dbId" : 74112,
    "stId" : "R-ALL-74112",
    "displayName" : "Ca2+ [extracellular region]",
    "schemaClass" : "SimpleEntity",
    "speciesId" : 0,
    "identifier" : "29108",
    "standardIdentifier" : "chebi:29108",
    "referenceType" : "ReferenceMolecule",
    "parents" : [ 10394812 ],
    "children" : [ ]
  }, {
    "dbId" : 10402079,
    "stId" : "R-BTA-5626551",
    "displayName" : "RAC1:GTP,CDC42:GTP:IQGAPs:CALM1:4Ca2+ [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 48898,
    "diagramIds" : [ 33529 ],
    "parents" : [ ],
    "children" : [ 10352212, 10402073 ]
  }, {
    "dbId" : 10349919,
    "stId" : "R-BTA-448839",
    "displayName" : "CTNNB1 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48898,
    "identifier" : "Q0VCX4",
    "standardIdentifier" : "uniprot:Q0VCX4",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "CTNNB1" ],
    "parents" : [ 10404370 ],
    "children" : [ ]
  }, {
    "dbId" : 10402077,
    "stId" : "R-BTA-5626510",
    "displayName" : "RAC1,CDC42:GTP:IQGAP:F-actin [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 48898,
    "diagramIds" : [ 33528 ],
    "parents" : [ ],
    "children" : [ 10364336, 10402073 ]
  }, {
    "dbId" : 10402073,
    "stId" : "R-BTA-5626465",
    "displayName" : "RAC1,CDC42:GTP:IQGAPs [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 48898,
    "diagramIds" : [ 33525 ],
    "parents" : [ 10402079, 10402077 ],
    "children" : [ 10402071, 10347838 ]
  }, {
    "dbId" : 10404374,
    "stId" : "R-BTA-5672317",
    "displayName" : "CDH1 dimer:CTTNB1:CTTNA1:IQGAP1:MEN1 [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 48898,
    "diagramIds" : [ 33536 ],
    "parents" : [ ],
    "children" : [ 10404370, 10404372, 10402057 ]
  }, {
    "dbId" : 10402071,
    "stId" : "R-BTA-5626373",
    "displayName" : "IQGAP [cytosol]",
    "schemaClass" : "DefinedSet",
    "speciesId" : 48898,
    "diagramIds" : [ 33524 ],
    "parents" : [ 10402073 ],
    "children" : [ 10402069, 10402057, 10402063 ]
  }, {
    "dbId" : 10352212,
    "stId" : "R-BTA-534997",
    "displayName" : "CALM1:4Ca2+ [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 48898,
    "diagramIds" : [ 33531 ],
    "parents" : [ 10402079 ],
    "children" : [ 10352210, 140648 ]
  }, {
    "dbId" : 10404372,
    "stId" : "R-BTA-5672315",
    "displayName" : "MEN1 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48898,
    "diagramIds" : [ 33535 ],
    "identifier" : "Q0P5I0",
    "standardIdentifier" : "uniprot:Q0P5I0",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "MEN1" ],
    "parents" : [ 10404374 ],
    "children" : [ ]
  }, {
    "dbId" : 10402069,
    "stId" : "R-BTA-5626528",
    "displayName" : "IQGAP3 dimer [cytosol]",
    "schemaClass" : "Complex",
    "speciesId" : 48898,
    "parents" : [ 10402071 ],
    "children" : [ 10402067 ]
  }, {
    "dbId" : 10404370,
    "stId" : "R-BTA-201938",
    "displayName" : "CDH1 dimer:CTNNB1:CTNNA1 [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 48898,
    "diagramIds" : [ 33533 ],
    "parents" : [ 10404374 ],
    "children" : [ 10362211, 10394812, 10349919 ]
  }, {
    "dbId" : 10402067,
    "stId" : "R-BTA-5625977",
    "displayName" : "IQGAP3 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48898,
    "identifier" : "A6H7H0",
    "standardIdentifier" : "uniprot:A6H7H0",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "IQGAP3" ],
    "parents" : [ 10402069 ],
    "children" : [ ]
  }, {
    "dbId" : 10352210,
    "stId" : "R-BTA-9016884",
    "displayName" : "CALM1 [plasma membrane]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48898,
    "identifier" : "A0A3Q1MR28",
    "standardIdentifier" : "uniprot:A0A3Q1MR28",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 10352212 ],
    "children" : [ ]
  }, {
    "dbId" : 10402063,
    "stId" : "R-BTA-5626532",
    "displayName" : "IQGAP2 dimer [cytosol]",
    "schemaClass" : "Complex",
    "speciesId" : 48898,
    "parents" : [ 10402071 ],
    "children" : [ 10402061 ]
  }, {
    "dbId" : 10402061,
    "stId" : "R-BTA-5625975",
    "displayName" : "IQGAP2 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48898,
    "identifier" : "F1MTR1",
    "standardIdentifier" : "uniprot:F1MTR1",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "IQGAP2" ],
    "parents" : [ 10402063 ],
    "children" : [ ]
  }, {
    "dbId" : 10402057,
    "stId" : "R-BTA-5626540",
    "displayName" : "IQGAP1 dimer [cytosol]",
    "schemaClass" : "Complex",
    "speciesId" : 48898,
    "diagramIds" : [ 33534 ],
    "parents" : [ 10404374, 10402071 ],
    "children" : [ 10402055 ]
  }, {
    "dbId" : 10402055,
    "stId" : "R-BTA-5626371",
    "displayName" : "IQGAP1 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48898,
    "identifier" : "F1MC48",
    "standardIdentifier" : "uniprot:F1MC48",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "IQGAP1" ],
    "parents" : [ 10402057 ],
    "children" : [ ]
  }, {
    "dbId" : 10352896,
    "stId" : "R-BTA-198003",
    "displayName" : "CDH1 [plasma membrane]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48898,
    "identifier" : "A0A3Q1MSS6",
    "standardIdentifier" : "uniprot:A0A3Q1MSS6",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "CDH1" ],
    "parents" : [ 10394812 ],
    "children" : [ ]
  }, {
    "dbId" : 10347836,
    "stId" : "R-BTA-449545",
    "displayName" : "CDC42 [plasma membrane]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48898,
    "identifier" : "Q2KJ93",
    "standardIdentifier" : "uniprot:Q2KJ93",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 10347838 ],
    "children" : [ ]
  }, {
    "dbId" : 10394812,
    "stId" : "R-BTA-2534182",
    "displayName" : "CDH1(155-882):Ca2+ dimer [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 48898,
    "parents" : [ 10404370 ],
    "children" : [ 10352896, 74112 ]
  }, {
    "dbId" : 10347838,
    "stId" : "R-BTA-182921",
    "displayName" : "CDC42:GTP [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 48898,
    "diagramIds" : [ 33523 ],
    "parents" : [ 10402073 ],
    "children" : [ 29438, 10347836 ]
  }, {
    "dbId" : 10352952,
    "stId" : "R-BTA-201857",
    "displayName" : "G-actin [cytosol]",
    "schemaClass" : "Complex",
    "speciesId" : 48898,
    "parents" : [ 10364336 ],
    "children" : [ 10352950, 113592 ]
  }, {
    "dbId" : 10352948,
    "stId" : "R-BTA-201858",
    "displayName" : "ACTB [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48898,
    "identifier" : "P60712",
    "standardIdentifier" : "uniprot:P60712",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "ACTB" ],
    "parents" : [ 10352950 ],
    "children" : [ ]
  }, {
    "dbId" : 140648,
    "stId" : "R-ALL-140648",
    "displayName" : "Ca2+ [plasma membrane]",
    "schemaClass" : "SimpleEntity",
    "speciesId" : 0,
    "identifier" : "29108",
    "standardIdentifier" : "chebi:29108",
    "referenceType" : "ReferenceMolecule",
    "parents" : [ 10352212 ],
    "children" : [ ]
  }, {
    "dbId" : 10352950,
    "stId" : "R-BTA-201859",
    "displayName" : "ACTB, ACTG1 [cytosol]",
    "schemaClass" : "DefinedSet",
    "speciesId" : 48898,
    "parents" : [ 10352952 ],
    "children" : [ 10352946, 10352948 ]
  }, {
    "dbId" : 10364336,
    "stId" : "R-BTA-201877",
    "displayName" : "F-actin [cytosol]",
    "schemaClass" : "Polymer",
    "speciesId" : 48898,
    "diagramIds" : [ 33527 ],
    "parents" : [ 10402077 ],
    "children" : [ 10352952 ]
  }, {
    "dbId" : 10352946,
    "stId" : "R-BTA-201861",
    "displayName" : "ACTG1 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48898,
    "identifier" : "P63258",
    "standardIdentifier" : "uniprot:P63258",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "ACTG1", "ACTG" ],
    "parents" : [ 10352950 ],
    "children" : [ ]
  }, {
    "dbId" : 113592,
    "stId" : "R-ALL-113592",
    "displayName" : "ATP [cytosol]",
    "schemaClass" : "SimpleEntity",
    "speciesId" : 0,
    "identifier" : "30616",
    "standardIdentifier" : "chebi:30616",
    "referenceType" : "ReferenceMolecule",
    "parents" : [ 10352952 ],
    "children" : [ ]
  }, {
    "dbId" : 10362211,
    "stId" : "R-BTA-191735",
    "displayName" : "CTNNA1 [plasma membrane]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48898,
    "identifier" : "A0A3Q1M9M0",
    "standardIdentifier" : "uniprot:A0A3Q1M9M0",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "CTNNA1" ],
    "parents" : [ 10404370 ],
    "children" : [ ]
  }, {
    "dbId" : 29438,
    "stId" : "R-ALL-29438",
    "displayName" : "GTP [cytosol]",
    "schemaClass" : "SimpleEntity",
    "speciesId" : 0,
    "identifier" : "37565",
    "standardIdentifier" : "chebi:37565",
    "referenceType" : "ReferenceMolecule",
    "parents" : [ 10347838 ],
    "children" : [ ]
  } ],
  "edges" : [ {
    "dbId" : 10402075,
    "stId" : "R-BTA-5626469",
    "displayName" : "GTP-bound RAC1 and CDC42 bind IQGAPs",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "following" : [ 10402084, 10402081 ],
    "inputs" : [ 10402071, 10347838 ],
    "outputs" : [ 10402073 ],
    "efs" : [ ],
    "diagramIds" : [ 33522 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10404376,
    "stId" : "R-BTA-5672304",
    "displayName" : "IQGAP1 binds CDH1:CTTNB1:CTTNA1 and MEN1",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "inputs" : [ 10404370, 10404372, 10402057 ],
    "outputs" : [ 10404374 ],
    "efs" : [ ],
    "inhibitors" : [ 10402073 ],
    "diagramIds" : [ 33532 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10402084,
    "stId" : "R-BTA-5626549",
    "displayName" : "IQGAPs bind CALM1",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "preceding" : [ 10402075 ],
    "inputs" : [ 10352212, 10402073 ],
    "outputs" : [ 10402079 ],
    "efs" : [ ],
    "diagramIds" : [ 33530 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10402081,
    "stId" : "R-BTA-5626507",
    "displayName" : "IQGAPs bind F-actin, which is inhibited by calmodulin",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "preceding" : [ 10402075 ],
    "inputs" : [ 10364336, 10402073 ],
    "outputs" : [ 10402077 ],
    "efs" : [ ],
    "inhibitors" : [ 10402079 ],
    "diagramIds" : [ 33526 ],
    "entityFunctionalStatus" : [ ]
  } ]
}