{
  "dbId" : 10443480,
  "stableId" : "R-BTA-453276",
  "displayName" : "Regulation of mitotic cell cycle",
  "nodes" : [ {
    "id" : 34176,
    "reactomeId" : 111294,
    "displayName" : "PPi",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 49,
      "y" : 1471
    },
    "minX" : 34,
    "maxX" : 84,
    "minY" : 1455,
    "maxY" : 1498,
    "prop" : {
      "x" : 34,
      "y" : 1456,
      "width" : 31,
      "height" : 30
    },
    "textPosition" : {
      "x" : 36,
      "y" : 1460
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 60,
          "y" : 1461
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 60,
          "y" : 1461
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 34173,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 68,
          "y" : 1482
        },
        "to" : {
          "x" : 84,
          "y" : 1498
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 76,
          "y" : 1484
        },
        "b" : {
          "x" : 68,
          "y" : 1482
        },
        "c" : {
          "x" : 70,
          "y" : 1490
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 70,
          "y" : 1490
        }
      }
    } ]
  }, {
    "id" : 34177,
    "reactomeId" : 10333424,
    "displayName" : "FZR1",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 162,
      "y" : 1467
    },
    "minX" : 80,
    "maxX" : 190,
    "minY" : 1307,
    "maxY" : 1498,
    "prop" : {
      "x" : 140,
      "y" : 1456,
      "width" : 44,
      "height" : 22
    },
    "textPosition" : {
      "x" : 142,
      "y" : 1456
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 184,
          "y" : 1456
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 184,
          "y" : 1456
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 34180,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 156,
          "y" : 1453
        },
        "to" : {
          "x" : 80,
          "y" : 1307
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 34173,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 137,
          "y" : 1475
        },
        "to" : {
          "x" : 84,
          "y" : 1498
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 132,
          "y" : 1481
        },
        "b" : {
          "x" : 137,
          "y" : 1475
        },
        "c" : {
          "x" : 129,
          "y" : 1474
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 129,
          "y" : 1474
        }
      }
    } ]
  }, {
    "id" : 34178,
    "reactomeId" : 10346506,
    "displayName" : "phospho-Cdh1 phosphatase",
    "schemaClass" : "CandidateSet",
    "renderableClass" : "EntitySet",
    "position" : {
      "x" : 166,
      "y" : 1536
    },
    "minX" : 92,
    "maxX" : 216,
    "minY" : 1518,
    "maxY" : 1554,
    "prop" : {
      "x" : 117,
      "y" : 1518,
      "width" : 99,
      "height" : 36
    },
    "textPosition" : {
      "x" : 115,
      "y" : 1518
    },
    "connectors" : [ {
      "edgeId" : 34173,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 111,
          "y" : 1536
        },
        "to" : {
          "x" : 100,
          "y" : 1536
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 96,
          "y" : 1536
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 96,
          "y" : 1536
        }
      }
    } ]
  }, {
    "id" : 34181,
    "reactomeId" : 10333426,
    "displayName" : "phospho-APC/C:Cdh1 complex",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 127,
      "y" : 1143
    },
    "minX" : 73,
    "maxX" : 239,
    "minY" : 1119,
    "maxY" : 1218,
    "prop" : {
      "x" : 73,
      "y" : 1125,
      "width" : 108,
      "height" : 36
    },
    "textPosition" : {
      "x" : 73,
      "y" : 1126
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 181,
          "y" : 1125
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 181,
          "y" : 1125
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 34180,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 34182,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 135,
          "y" : 1164
        },
        "to" : {
          "x" : 164,
          "y" : 1218
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 34188,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 184,
          "y" : 1140
        },
        "to" : {
          "x" : 239,
          "y" : 1138
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 191,
          "y" : 1136
        },
        "b" : {
          "x" : 184,
          "y" : 1140
        },
        "c" : {
          "x" : 191,
          "y" : 1144
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 191,
          "y" : 1144
        }
      }
    } ]
  }, {
    "id" : 34183,
    "reactomeId" : 10346437,
    "displayName" : "(APC/C:Cdh1)-targeted cell cycle proteins",
    "schemaClass" : "DefinedSet",
    "renderableClass" : "EntitySet",
    "position" : {
      "x" : 192,
      "y" : 1353
    },
    "minX" : 138,
    "maxX" : 247,
    "minY" : 1218,
    "maxY" : 1378,
    "prop" : {
      "x" : 138,
      "y" : 1328,
      "width" : 109,
      "height" : 50
    },
    "textPosition" : {
      "x" : 145,
      "y" : 1328
    },
    "connectors" : [ {
      "edgeId" : 34182,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 186,
          "y" : 1322
        },
        "to" : {
          "x" : 164,
          "y" : 1218
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 34184,
    "reactomeId" : 10346439,
    "displayName" : "cell cycle proteins:phospho-APC/C:Cdh1 complex",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 261,
      "y" : 1220
    },
    "minX" : 213,
    "maxX" : 358,
    "minY" : 1177,
    "maxY" : 1257,
    "prop" : {
      "x" : 213,
      "y" : 1183,
      "width" : 96,
      "height" : 74
    },
    "textPosition" : {
      "x" : 219,
      "y" : 1180
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 309,
          "y" : 1183
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 309,
          "y" : 1183
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 34182,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 34185,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 312,
          "y" : 1220
        },
        "to" : {
          "x" : 358,
          "y" : 1220
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 34185,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 312,
          "y" : 1201
        },
        "to" : {
          "x" : 327,
          "y" : 1195
        }
      }, {
        "from" : {
          "x" : 327,
          "y" : 1195
        },
        "to" : {
          "x" : 342,
          "y" : 1195
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 346,
          "y" : 1195
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 346,
          "y" : 1195
        }
      }
    } ]
  }, {
    "id" : 34186,
    "reactomeId" : 10333291,
    "displayName" : "Ub",
    "schemaClass" : "DefinedSet",
    "renderableClass" : "EntitySet",
    "position" : {
      "x" : 360,
      "y" : 1281
    },
    "minX" : 322,
    "maxX" : 398,
    "minY" : 1220,
    "maxY" : 1292,
    "prop" : {
      "x" : 322,
      "y" : 1270,
      "width" : 76,
      "height" : 22
    },
    "textPosition" : {
      "x" : 347,
      "y" : 1270
    },
    "connectors" : [ {
      "edgeId" : 34185,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 359,
          "y" : 1264
        },
        "to" : {
          "x" : 358,
          "y" : 1220
        }
      } ],
      "stoichiometry" : {
        "value" : 4,
        "shape" : {
          "a" : {
            "x" : 352,
            "y" : 1236
          },
          "b" : {
            "x" : 364,
            "y" : 1248
          },
          "type" : "BOX",
          "empty" : true,
          "centre" : {
            "x" : 358,
            "y" : 1242
          }
        }
      }
    } ]
  }, {
    "id" : 34187,
    "reactomeId" : 10346458,
    "displayName" : "multiubiquitinated cell cycle protein:APC/C:Cdh1 complex",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 358,
      "y" : 1139
    },
    "minX" : 292,
    "maxX" : 431,
    "minY" : 1101,
    "maxY" : 1171,
    "prop" : {
      "x" : 292,
      "y" : 1107,
      "width" : 133,
      "height" : 64
    },
    "textPosition" : {
      "x" : 296,
      "y" : 1108
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 425,
          "y" : 1107
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 425,
          "y" : 1107
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 34185,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 34188,
      "type" : "INPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 34189,
    "reactomeId" : 10333291,
    "displayName" : "Ub",
    "schemaClass" : "DefinedSet",
    "renderableClass" : "EntitySet",
    "position" : {
      "x" : 225,
      "y" : 1082
    },
    "minX" : 193,
    "maxX" : 258,
    "minY" : 1072,
    "maxY" : 1138,
    "prop" : {
      "x" : 193,
      "y" : 1072,
      "width" : 65,
      "height" : 20
    },
    "textPosition" : {
      "x" : 213,
      "y" : 1072
    },
    "connectors" : [ {
      "edgeId" : 34188,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 227,
          "y" : 1098
        },
        "to" : {
          "x" : 239,
          "y" : 1138
        }
      } ],
      "stoichiometry" : {
        "value" : 4,
        "shape" : {
          "a" : {
            "x" : 227,
            "y" : 1112
          },
          "b" : {
            "x" : 239,
            "y" : 1124
          },
          "type" : "BOX",
          "empty" : true,
          "centre" : {
            "x" : 233,
            "y" : 1118
          }
        }
      },
      "endShape" : {
        "a" : {
          "x" : 233,
          "y" : 1103
        },
        "b" : {
          "x" : 227,
          "y" : 1098
        },
        "c" : {
          "x" : 225,
          "y" : 1106
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 225,
          "y" : 1106
        }
      }
    } ]
  }, {
    "id" : 34191,
    "reactomeId" : 10332827,
    "displayName" : "Ub",
    "schemaClass" : "DefinedSet",
    "renderableClass" : "EntitySet",
    "position" : {
      "x" : 934,
      "y" : 414
    },
    "minX" : 902,
    "maxX" : 1275,
    "minY" : 341,
    "maxY" : 425,
    "prop" : {
      "x" : 902,
      "y" : 403,
      "width" : 64,
      "height" : 22
    },
    "textPosition" : {
      "x" : 921,
      "y" : 403
    },
    "connectors" : [ {
      "edgeId" : 34190,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 932,
          "y" : 397
        },
        "to" : {
          "x" : 928,
          "y" : 369
        }
      } ],
      "stoichiometry" : {
        "value" : 3,
        "shape" : {
          "a" : {
            "x" : 924,
            "y" : 377
          },
          "b" : {
            "x" : 936,
            "y" : 389
          },
          "type" : "BOX",
          "empty" : true,
          "centre" : {
            "x" : 930,
            "y" : 383
          }
        }
      }
    }, {
      "edgeId" : 34204,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 972,
          "y" : 407
        },
        "to" : {
          "x" : 1275,
          "y" : 341
        }
      } ],
      "stoichiometry" : {
        "value" : 3,
        "shape" : {
          "a" : {
            "x" : 1117,
            "y" : 368
          },
          "b" : {
            "x" : 1129,
            "y" : 380
          },
          "type" : "BOX",
          "empty" : true,
          "centre" : {
            "x" : 1123,
            "y" : 374
          }
        }
      }
    } ]
  }, {
    "id" : 34192,
    "reactomeId" : 10346410,
    "displayName" : "multiubiquitinated Cdh1 associated with APC/C",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 929,
      "y" : 252
    },
    "minX" : 864,
    "maxX" : 1000,
    "minY" : 221,
    "maxY" : 277,
    "prop" : {
      "x" : 864,
      "y" : 227,
      "width" : 130,
      "height" : 50
    },
    "textPosition" : {
      "x" : 866,
      "y" : 228
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 994,
          "y" : 227
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 994,
          "y" : 227
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 34190,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 34193,
      "type" : "INPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 34194,
    "reactomeId" : 10332827,
    "displayName" : "Ub",
    "schemaClass" : "DefinedSet",
    "renderableClass" : "EntitySet",
    "position" : {
      "x" : 710,
      "y" : 216
    },
    "minX" : 303,
    "maxX" : 747,
    "minY" : 91,
    "maxY" : 275,
    "prop" : {
      "x" : 677,
      "y" : 205,
      "width" : 67,
      "height" : 22
    },
    "textPosition" : {
      "x" : 698,
      "y" : 205
    },
    "connectors" : [ {
      "edgeId" : 34193,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 716,
          "y" : 233
        },
        "to" : {
          "x" : 747,
          "y" : 275
        }
      } ],
      "stoichiometry" : {
        "value" : 3,
        "shape" : {
          "a" : {
            "x" : 725,
            "y" : 248
          },
          "b" : {
            "x" : 737,
            "y" : 260
          },
          "type" : "BOX",
          "empty" : true,
          "centre" : {
            "x" : 731,
            "y" : 254
          }
        }
      },
      "endShape" : {
        "a" : {
          "x" : 723,
          "y" : 236
        },
        "b" : {
          "x" : 716,
          "y" : 233
        },
        "c" : {
          "x" : 717,
          "y" : 241
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 717,
          "y" : 241
        }
      }
    }, {
      "edgeId" : 34198,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 698,
          "y" : 199
        },
        "to" : {
          "x" : 643,
          "y" : 152
        }
      }, {
        "from" : {
          "x" : 643,
          "y" : 152
        },
        "to" : {
          "x" : 303,
          "y" : 91
        }
      } ],
      "stoichiometry" : {
        "value" : 3,
        "shape" : {
          "a" : {
            "x" : 664,
            "y" : 169
          },
          "b" : {
            "x" : 676,
            "y" : 181
          },
          "type" : "BOX",
          "empty" : true,
          "centre" : {
            "x" : 670,
            "y" : 175
          }
        }
      },
      "endShape" : {
        "a" : {
          "x" : 690,
          "y" : 198
        },
        "b" : {
          "x" : 698,
          "y" : 199
        },
        "c" : {
          "x" : 695,
          "y" : 191
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 695,
          "y" : 191
        }
      }
    } ]
  }, {
    "id" : 34195,
    "reactomeId" : 10333048,
    "displayName" : "26S proteasome",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 791,
      "y" : 185
    },
    "minX" : 735,
    "maxX" : 951,
    "minY" : 168,
    "maxY" : 256,
    "prop" : {
      "x" : 735,
      "y" : 174,
      "width" : 113,
      "height" : 22
    },
    "textPosition" : {
      "x" : 735,
      "y" : 175
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 848,
          "y" : 174
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 848,
          "y" : 174
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 34193,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 791,
          "y" : 199
        },
        "to" : {
          "x" : 796,
          "y" : 248
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 796,
          "y" : 252
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 796,
          "y" : 252
        }
      }
    }, {
      "edgeId" : 34198,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 851,
          "y" : 193
        },
        "to" : {
          "x" : 940,
          "y" : 208
        }
      }, {
        "from" : {
          "x" : 940,
          "y" : 208
        },
        "to" : {
          "x" : 946,
          "y" : 188
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 947,
          "y" : 185
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 947,
          "y" : 185
        }
      }
    } ]
  }, {
    "id" : 34197,
    "reactomeId" : 10346580,
    "displayName" : "hBUBR1:hBUB3:MAD2* complex",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 1224,
      "y" : 1362
    },
    "minX" : 1160,
    "maxX" : 1294,
    "minY" : 1300,
    "maxY" : 1380,
    "prop" : {
      "x" : 1160,
      "y" : 1344,
      "width" : 128,
      "height" : 36
    },
    "textPosition" : {
      "x" : 1171,
      "y" : 1345
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1288,
          "y" : 1344
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1288,
          "y" : 1344
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 34196,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 1205,
          "y" : 1341
        },
        "to" : {
          "x" : 1161,
          "y" : 1300
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 1197,
          "y" : 1339
        },
        "b" : {
          "x" : 1205,
          "y" : 1341
        },
        "c" : {
          "x" : 1203,
          "y" : 1333
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 1203,
          "y" : 1333
        }
      }
    } ]
  }, {
    "id" : 34199,
    "reactomeId" : 10348232,
    "displayName" : "PolyUb-SKP2:RB1:phospho-APC/C:Cdh1 complex",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 1089,
      "y" : 249
    },
    "minX" : 1027,
    "maxX" : 1157,
    "minY" : 217,
    "maxY" : 276,
    "prop" : {
      "x" : 1027,
      "y" : 223,
      "width" : 124,
      "height" : 53
    },
    "textPosition" : {
      "x" : 1030,
      "y" : 227
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1151,
          "y" : 223
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1151,
          "y" : 223
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 34198,
      "type" : "INPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 34204,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 34200,
    "reactomeId" : 10333582,
    "displayName" : "RB1",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 982,
      "y" : 127
    },
    "minX" : 303,
    "maxX" : 1197,
    "minY" : 91,
    "maxY" : 138,
    "prop" : {
      "x" : 943,
      "y" : 117,
      "width" : 78,
      "height" : 21
    },
    "textPosition" : {
      "x" : 966,
      "y" : 117
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1021,
          "y" : 117
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1021,
          "y" : 117
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 34198,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 940,
          "y" : 124
        },
        "to" : {
          "x" : 303,
          "y" : 91
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 933,
          "y" : 128
        },
        "b" : {
          "x" : 940,
          "y" : 124
        },
        "c" : {
          "x" : 933,
          "y" : 120
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 933,
          "y" : 120
        }
      }
    }, {
      "edgeId" : 34201,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1024,
          "y" : 120
        },
        "to" : {
          "x" : 1197,
          "y" : 92
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 34202,
    "reactomeId" : 10333248,
    "displayName" : "SKP2",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 1267,
      "y" : 95
    },
    "minX" : 1197,
    "maxX" : 1295,
    "minY" : 77,
    "maxY" : 107,
    "prop" : {
      "x" : 1246,
      "y" : 83,
      "width" : 43,
      "height" : 24
    },
    "textPosition" : {
      "x" : 1248,
      "y" : 84
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1289,
          "y" : 83
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1289,
          "y" : 83
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 34201,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1243,
          "y" : 94
        },
        "to" : {
          "x" : 1197,
          "y" : 92
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 34203,
    "reactomeId" : 10434080,
    "displayName" : "RB1:SKP2:APC/C:Cdh1",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 1221,
      "y" : 218
    },
    "minX" : 1177,
    "maxX" : 1289,
    "minY" : 195,
    "maxY" : 341,
    "prop" : {
      "x" : 1177,
      "y" : 201,
      "width" : 88,
      "height" : 35
    },
    "textPosition" : {
      "x" : 1181,
      "y" : 201
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1265,
          "y" : 201
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1265,
          "y" : 201
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 34201,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 34204,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1268,
          "y" : 225
        },
        "to" : {
          "x" : 1289,
          "y" : 229
        }
      }, {
        "from" : {
          "x" : 1289,
          "y" : 229
        },
        "to" : {
          "x" : 1275,
          "y" : 341
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 34204,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 1221,
          "y" : 239
        },
        "to" : {
          "x" : 1223,
          "y" : 303
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 1223,
          "y" : 307
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1223,
          "y" : 307
        }
      }
    } ]
  }, {
    "id" : 34209,
    "reactomeId" : 10346535,
    "displayName" : "Cdc20/Cdh1",
    "schemaClass" : "DefinedSet",
    "renderableClass" : "EntitySet",
    "position" : {
      "x" : 409,
      "y" : 1347
    },
    "minX" : 362,
    "maxX" : 457,
    "minY" : 1338,
    "maxY" : 1357,
    "prop" : {
      "x" : 362,
      "y" : 1338,
      "width" : 95,
      "height" : 19
    },
    "textPosition" : {
      "x" : 368,
      "y" : 1337
    },
    "connectors" : [ ]
  }, {
    "id" : 34092,
    "reactomeId" : 10333230,
    "displayName" : "CCNA:p-T160-CDK2",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 120,
      "y" : 219
    },
    "minX" : 63,
    "maxX" : 210,
    "minY" : 188,
    "maxY" : 244,
    "prop" : {
      "x" : 63,
      "y" : 194,
      "width" : 114,
      "height" : 50
    },
    "textPosition" : {
      "x" : 74,
      "y" : 209
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 177,
          "y" : 194
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 177,
          "y" : 194
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 34091,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 180,
          "y" : 218
        },
        "to" : {
          "x" : 210,
          "y" : 218
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 34093,
    "reactomeId" : 10346420,
    "displayName" : "Cdh1:phospho-APC/C complex",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 213,
      "y" : 165
    },
    "minX" : 161,
    "maxX" : 1197,
    "minY" : 84,
    "maxY" : 218,
    "prop" : {
      "x" : 161,
      "y" : 147,
      "width" : 104,
      "height" : 36
    },
    "textPosition" : {
      "x" : 161,
      "y" : 148
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 265,
          "y" : 147
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 265,
          "y" : 147
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 34198,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 234,
          "y" : 144
        },
        "to" : {
          "x" : 303,
          "y" : 91
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 237,
          "y" : 137
        },
        "b" : {
          "x" : 234,
          "y" : 144
        },
        "c" : {
          "x" : 242,
          "y" : 143
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 242,
          "y" : 143
        }
      }
    }, {
      "edgeId" : 34201,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 231,
          "y" : 144
        },
        "to" : {
          "x" : 298,
          "y" : 84
        }
      }, {
        "from" : {
          "x" : 298,
          "y" : 84
        },
        "to" : {
          "x" : 1197,
          "y" : 92
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 34091,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 211,
          "y" : 186
        },
        "to" : {
          "x" : 210,
          "y" : 218
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 34094,
    "reactomeId" : 10346422,
    "displayName" : "Cyclin A:phospho-Cdk(Thr 160):Cdh1:phosho-APC/C complex",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 335,
      "y" : 218
    },
    "minX" : 274,
    "maxX" : 453,
    "minY" : 180,
    "maxY" : 250,
    "prop" : {
      "x" : 274,
      "y" : 186,
      "width" : 123,
      "height" : 64
    },
    "textPosition" : {
      "x" : 276,
      "y" : 187
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 397,
          "y" : 186
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 397,
          "y" : 186
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 34091,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 34095,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 400,
          "y" : 206
        },
        "to" : {
          "x" : 423,
          "y" : 202
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 34095,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 400,
          "y" : 226
        },
        "to" : {
          "x" : 449,
          "y" : 233
        }
      }, {
        "from" : {
          "x" : 449,
          "y" : 233
        },
        "to" : {
          "x" : 449,
          "y" : 219
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 449,
          "y" : 215
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 449,
          "y" : 215
        }
      }
    } ]
  }, {
    "id" : 34096,
    "reactomeId" : 29358,
    "displayName" : "ATP",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 374,
      "y" : 158
    },
    "minX" : 355,
    "maxX" : 423,
    "minY" : 142,
    "maxY" : 202,
    "prop" : {
      "x" : 355,
      "y" : 143,
      "width" : 38,
      "height" : 30
    },
    "textPosition" : {
      "x" : 358,
      "y" : 147
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 388,
          "y" : 148
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 388,
          "y" : 148
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 34095,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 390,
          "y" : 176
        },
        "to" : {
          "x" : 423,
          "y" : 202
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 34097,
    "reactomeId" : 113582,
    "displayName" : "ADP",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 507,
      "y" : 154
    },
    "minX" : 478,
    "maxX" : 528,
    "minY" : 138,
    "maxY" : 204,
    "prop" : {
      "x" : 488,
      "y" : 139,
      "width" : 39,
      "height" : 30
    },
    "textPosition" : {
      "x" : 491,
      "y" : 143
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 522,
          "y" : 144
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 522,
          "y" : 144
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 34095,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 498,
          "y" : 172
        },
        "to" : {
          "x" : 478,
          "y" : 204
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 498,
          "y" : 180
        },
        "b" : {
          "x" : 498,
          "y" : 172
        },
        "c" : {
          "x" : 491,
          "y" : 176
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 491,
          "y" : 176
        }
      }
    } ]
  }, {
    "id" : 34098,
    "reactomeId" : 10346424,
    "displayName" : "Cyclin A:phospho-Cdk2(Thr 160):phospho-Cdh1:phospho-APC/C complex",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 577,
      "y" : 220
    },
    "minX" : 478,
    "maxX" : 660,
    "minY" : 179,
    "maxY" : 255,
    "prop" : {
      "x" : 501,
      "y" : 185,
      "width" : 153,
      "height" : 70
    },
    "textPosition" : {
      "x" : 503,
      "y" : 192
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 654,
          "y" : 185
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 654,
          "y" : 185
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 34095,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 498,
          "y" : 207
        },
        "to" : {
          "x" : 478,
          "y" : 204
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 491,
          "y" : 210
        },
        "b" : {
          "x" : 498,
          "y" : 207
        },
        "c" : {
          "x" : 492,
          "y" : 202
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 492,
          "y" : 202
        }
      }
    } ]
  }, {
    "id" : 34100,
    "reactomeId" : 10332913,
    "displayName" : "phospho-Cdh1:phospho-APC/C complex",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 820,
      "y" : 319
    },
    "minX" : 767,
    "maxX" : 928,
    "minY" : 288,
    "maxY" : 369,
    "prop" : {
      "x" : 767,
      "y" : 294,
      "width" : 106,
      "height" : 50
    },
    "textPosition" : {
      "x" : 767,
      "y" : 295
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 873,
          "y" : 294
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 873,
          "y" : 294
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 34190,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 876,
          "y" : 343
        },
        "to" : {
          "x" : 928,
          "y" : 369
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 34190,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 876,
          "y" : 318
        },
        "to" : {
          "x" : 912,
          "y" : 317
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 916,
          "y" : 317
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 916,
          "y" : 317
        }
      }
    }, {
      "edgeId" : 34099,
      "type" : "INPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 34101,
    "reactomeId" : 10332911,
    "displayName" : "phosphorylated anaphase promoting complex (APC/C)",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 344,
      "y" : 308
    },
    "minX" : 292,
    "maxX" : 747,
    "minY" : 265,
    "maxY" : 346,
    "prop" : {
      "x" : 292,
      "y" : 271,
      "width" : 104,
      "height" : 75
    },
    "textPosition" : {
      "x" : 295,
      "y" : 269
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 396,
          "y" : 271
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 396,
          "y" : 271
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 34193,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 399,
          "y" : 303
        },
        "to" : {
          "x" : 747,
          "y" : 275
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 406,
          "y" : 298
        },
        "b" : {
          "x" : 399,
          "y" : 303
        },
        "c" : {
          "x" : 406,
          "y" : 306
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 406,
          "y" : 306
        }
      }
    }, {
      "edgeId" : 34140,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 34141,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 34099,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 399,
          "y" : 309
        },
        "to" : {
          "x" : 675,
          "y" : 319
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 406,
          "y" : 305
        },
        "b" : {
          "x" : 399,
          "y" : 309
        },
        "c" : {
          "x" : 406,
          "y" : 313
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 406,
          "y" : 313
        }
      }
    } ]
  }, {
    "id" : 34102,
    "reactomeId" : 10332835,
    "displayName" : "phospho-FZR1",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 637,
      "y" : 353
    },
    "minX" : 556,
    "maxX" : 697,
    "minY" : 319,
    "maxY" : 389,
    "prop" : {
      "x" : 583,
      "y" : 342,
      "width" : 108,
      "height" : 22
    },
    "textPosition" : {
      "x" : 587,
      "y" : 342
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 691,
          "y" : 342
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 691,
          "y" : 342
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 34125,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 612,
          "y" : 367
        },
        "to" : {
          "x" : 556,
          "y" : 389
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 607,
          "y" : 373
        },
        "b" : {
          "x" : 612,
          "y" : 367
        },
        "c" : {
          "x" : 604,
          "y" : 366
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 604,
          "y" : 366
        }
      }
    }, {
      "edgeId" : 34099,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 649,
          "y" : 339
        },
        "to" : {
          "x" : 675,
          "y" : 319
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 652,
          "y" : 332
        },
        "b" : {
          "x" : 649,
          "y" : 339
        },
        "c" : {
          "x" : 657,
          "y" : 338
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 657,
          "y" : 338
        }
      }
    } ]
  }, {
    "id" : 34104,
    "reactomeId" : 10346443,
    "displayName" : "Cdh1",
    "schemaClass" : "DefinedSet",
    "renderableClass" : "EntitySet",
    "position" : {
      "x" : 680,
      "y" : 483
    },
    "minX" : 650,
    "maxX" : 744,
    "minY" : 472,
    "maxY" : 494,
    "prop" : {
      "x" : 650,
      "y" : 472,
      "width" : 60,
      "height" : 22
    },
    "textPosition" : {
      "x" : 660,
      "y" : 472
    },
    "connectors" : [ {
      "edgeId" : 34103,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 716,
          "y" : 483
        },
        "to" : {
          "x" : 744,
          "y" : 483
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 34105,
    "reactomeId" : 10343832,
    "displayName" : "FBXO5",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 725,
      "y" : 525
    },
    "minX" : 701,
    "maxX" : 817,
    "minY" : 483,
    "maxY" : 576,
    "prop" : {
      "x" : 701,
      "y" : 514,
      "width" : 48,
      "height" : 22
    },
    "textPosition" : {
      "x" : 701,
      "y" : 514
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 749,
          "y" : 514
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 749,
          "y" : 514
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 34103,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 729,
          "y" : 511
        },
        "to" : {
          "x" : 744,
          "y" : 483
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 34107,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 744,
          "y" : 539
        },
        "to" : {
          "x" : 817,
          "y" : 576
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 34106,
    "reactomeId" : 10346445,
    "displayName" : "Emi1:Cdh1 complex",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 908,
      "y" : 483
    },
    "minX" : 839,
    "maxX" : 984,
    "minY" : 466,
    "maxY" : 494,
    "prop" : {
      "x" : 839,
      "y" : 472,
      "width" : 139,
      "height" : 22
    },
    "textPosition" : {
      "x" : 844,
      "y" : 473
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 978,
          "y" : 472
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 978,
          "y" : 472
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 34103,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 34108,
    "reactomeId" : 10346486,
    "displayName" : "CDC20",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 874,
      "y" : 527
    },
    "minX" : 817,
    "maxX" : 905,
    "minY" : 510,
    "maxY" : 576,
    "prop" : {
      "x" : 850,
      "y" : 516,
      "width" : 49,
      "height" : 22
    },
    "textPosition" : {
      "x" : 850,
      "y" : 516
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 899,
          "y" : 516
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 899,
          "y" : 516
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 34107,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 861,
          "y" : 541
        },
        "to" : {
          "x" : 817,
          "y" : 576
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 34109,
    "reactomeId" : 10346576,
    "displayName" : "Emi1:Cdc20 complex",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 817,
      "y" : 656
    },
    "minX" : 770,
    "maxX" : 871,
    "minY" : 634,
    "maxY" : 673,
    "prop" : {
      "x" : 770,
      "y" : 640,
      "width" : 95,
      "height" : 33
    },
    "textPosition" : {
      "x" : 775,
      "y" : 638
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 865,
          "y" : 640
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 865,
          "y" : 640
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 34107,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 34111,
    "reactomeId" : 29358,
    "displayName" : "ATP",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 232,
      "y" : 505
    },
    "minX" : 213,
    "maxX" : 301,
    "minY" : 489,
    "maxY" : 528,
    "prop" : {
      "x" : 213,
      "y" : 490,
      "width" : 38,
      "height" : 30
    },
    "textPosition" : {
      "x" : 216,
      "y" : 494
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 246,
          "y" : 495
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 246,
          "y" : 495
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 34110,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 254,
          "y" : 511
        },
        "to" : {
          "x" : 301,
          "y" : 528
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 34112,
    "reactomeId" : 10346490,
    "displayName" : "Emi1:Cdc20/Cdh1 complex",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 237,
      "y" : 571
    },
    "minX" : 168,
    "maxX" : 313,
    "minY" : 528,
    "maxY" : 616,
    "prop" : {
      "x" : 168,
      "y" : 553,
      "width" : 139,
      "height" : 37
    },
    "textPosition" : {
      "x" : 177,
      "y" : 555
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 307,
          "y" : 553
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 307,
          "y" : 553
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 34116,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 264,
          "y" : 593
        },
        "to" : {
          "x" : 305,
          "y" : 616
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 34110,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 264,
          "y" : 550
        },
        "to" : {
          "x" : 301,
          "y" : 528
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 34113,
    "reactomeId" : 10346495,
    "displayName" : "Phospho-Emi1(Ser 182):Cdc20/Cdh1 complexes",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 504,
      "y" : 538
    },
    "minX" : 357,
    "maxX" : 589,
    "minY" : 507,
    "maxY" : 563,
    "prop" : {
      "x" : 425,
      "y" : 513,
      "width" : 158,
      "height" : 50
    },
    "textPosition" : {
      "x" : 440,
      "y" : 514
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 583,
          "y" : 513
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 583,
          "y" : 513
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 34110,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 422,
          "y" : 532
        },
        "to" : {
          "x" : 357,
          "y" : 528
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 415,
          "y" : 536
        },
        "b" : {
          "x" : 422,
          "y" : 532
        },
        "c" : {
          "x" : 415,
          "y" : 528
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 415,
          "y" : 528
        }
      }
    } ]
  }, {
    "id" : 34114,
    "reactomeId" : 113582,
    "displayName" : "ADP",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 440,
      "y" : 470
    },
    "minX" : 357,
    "maxX" : 461,
    "minY" : 454,
    "maxY" : 528,
    "prop" : {
      "x" : 421,
      "y" : 455,
      "width" : 39,
      "height" : 30
    },
    "textPosition" : {
      "x" : 424,
      "y" : 459
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 455,
          "y" : 460
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 455,
          "y" : 460
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 34110,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 418,
          "y" : 483
        },
        "to" : {
          "x" : 357,
          "y" : 528
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 415,
          "y" : 490
        },
        "b" : {
          "x" : 418,
          "y" : 483
        },
        "c" : {
          "x" : 410,
          "y" : 484
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 410,
          "y" : 484
        }
      }
    } ]
  }, {
    "id" : 34115,
    "reactomeId" : 10345739,
    "displayName" : "CCNB1:p-T161-CDK1",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 333,
      "y" : 419
    },
    "minX" : 247,
    "maxX" : 547,
    "minY" : 309,
    "maxY" : 520,
    "prop" : {
      "x" : 261,
      "y" : 403,
      "width" : 145,
      "height" : 33
    },
    "textPosition" : {
      "x" : 267,
      "y" : 415
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 406,
          "y" : 403
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 406,
          "y" : 403
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 34125,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 409,
          "y" : 418
        },
        "to" : {
          "x" : 539,
          "y" : 416
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 543,
          "y" : 416
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 543,
          "y" : 416
        }
      }
    }, {
      "edgeId" : 34141,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 320,
          "y" : 400
        },
        "to" : {
          "x" : 253,
          "y" : 316
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 251,
          "y" : 313
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 251,
          "y" : 313
        }
      }
    }, {
      "edgeId" : 34110,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 332,
          "y" : 439
        },
        "to" : {
          "x" : 330,
          "y" : 512
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 329,
          "y" : 516
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 329,
          "y" : 516
        }
      }
    } ]
  }, {
    "id" : 34117,
    "reactomeId" : 29358,
    "displayName" : "ATP",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 222,
      "y" : 635
    },
    "minX" : 203,
    "maxX" : 305,
    "minY" : 616,
    "maxY" : 650,
    "prop" : {
      "x" : 203,
      "y" : 620,
      "width" : 38,
      "height" : 30
    },
    "textPosition" : {
      "x" : 206,
      "y" : 624
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 236,
          "y" : 625
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 236,
          "y" : 625
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 34116,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 244,
          "y" : 630
        },
        "to" : {
          "x" : 305,
          "y" : 616
        }
      } ],
      "stoichiometry" : {
        "value" : 2,
        "shape" : {
          "a" : {
            "x" : 268,
            "y" : 617
          },
          "b" : {
            "x" : 280,
            "y" : 629
          },
          "type" : "BOX",
          "empty" : true,
          "centre" : {
            "x" : 274,
            "y" : 623
          }
        }
      }
    } ]
  }, {
    "id" : 34118,
    "reactomeId" : 113582,
    "displayName" : "ADP",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 430,
      "y" : 672
    },
    "minX" : 378,
    "maxX" : 451,
    "minY" : 616,
    "maxY" : 687,
    "prop" : {
      "x" : 411,
      "y" : 657,
      "width" : 39,
      "height" : 30
    },
    "textPosition" : {
      "x" : 414,
      "y" : 661
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 445,
          "y" : 662
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 445,
          "y" : 662
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 34116,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 416,
          "y" : 654
        },
        "to" : {
          "x" : 378,
          "y" : 616
        }
      } ],
      "stoichiometry" : {
        "value" : 2,
        "shape" : {
          "a" : {
            "x" : 391,
            "y" : 629
          },
          "b" : {
            "x" : 403,
            "y" : 641
          },
          "type" : "BOX",
          "empty" : true,
          "centre" : {
            "x" : 397,
            "y" : 635
          }
        }
      },
      "endShape" : {
        "a" : {
          "x" : 408,
          "y" : 652
        },
        "b" : {
          "x" : 416,
          "y" : 654
        },
        "c" : {
          "x" : 414,
          "y" : 646
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 414,
          "y" : 646
        }
      }
    } ]
  }, {
    "id" : 34119,
    "reactomeId" : 10346562,
    "displayName" : "phospho-Emi1(Ser 145, Ser 149):Cdc20/Cdh1 complexes",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 502,
      "y" : 595
    },
    "minX" : 378,
    "maxX" : 592,
    "minY" : 564,
    "maxY" : 621,
    "prop" : {
      "x" : 418,
      "y" : 570,
      "width" : 168,
      "height" : 51
    },
    "textPosition" : {
      "x" : 422,
      "y" : 572
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 586,
          "y" : 570
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 586,
          "y" : 570
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 34116,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 415,
          "y" : 609
        },
        "to" : {
          "x" : 378,
          "y" : 616
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 409,
          "y" : 614
        },
        "b" : {
          "x" : 415,
          "y" : 609
        },
        "c" : {
          "x" : 407,
          "y" : 606
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 407,
          "y" : 606
        }
      }
    } ]
  }, {
    "id" : 34120,
    "reactomeId" : 10342926,
    "displayName" : "phospho-p-T210-PLK1",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 198,
      "y" : 441
    },
    "minX" : 152,
    "maxX" : 335,
    "minY" : 337,
    "maxY" : 608,
    "prop" : {
      "x" : 152,
      "y" : 430,
      "width" : 92,
      "height" : 22
    },
    "textPosition" : {
      "x" : 158,
      "y" : 424
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 244,
          "y" : 430
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 244,
          "y" : 430
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 34116,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 227,
          "y" : 455
        },
        "to" : {
          "x" : 301,
          "y" : 479
        }
      }, {
        "from" : {
          "x" : 301,
          "y" : 479
        },
        "to" : {
          "x" : 330,
          "y" : 600
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 331,
          "y" : 604
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 331,
          "y" : 604
        }
      }
    }, {
      "edgeId" : 34140,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 199,
          "y" : 427
        },
        "to" : {
          "x" : 212,
          "y" : 345
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 213,
          "y" : 341
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 213,
          "y" : 341
        }
      }
    } ]
  }, {
    "id" : 34122,
    "reactomeId" : 10333291,
    "displayName" : "Ub",
    "schemaClass" : "DefinedSet",
    "renderableClass" : "EntitySet",
    "position" : {
      "x" : 673,
      "y" : 761
    },
    "minX" : 557,
    "maxX" : 929,
    "minY" : 750,
    "maxY" : 842,
    "prop" : {
      "x" : 637,
      "y" : 750,
      "width" : 73,
      "height" : 22
    },
    "textPosition" : {
      "x" : 661,
      "y" : 750
    },
    "connectors" : [ {
      "edgeId" : 34121,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 631,
          "y" : 760
        },
        "to" : {
          "x" : 557,
          "y" : 759
        }
      } ],
      "stoichiometry" : {
        "value" : 3,
        "shape" : {
          "a" : {
            "x" : 588,
            "y" : 753
          },
          "b" : {
            "x" : 600,
            "y" : 765
          },
          "type" : "BOX",
          "empty" : true,
          "centre" : {
            "x" : 594,
            "y" : 759
          }
        }
      }
    }, {
      "edgeId" : 34170,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 707,
          "y" : 778
        },
        "to" : {
          "x" : 929,
          "y" : 842
        }
      } ],
      "stoichiometry" : {
        "value" : 3,
        "shape" : {
          "a" : {
            "x" : 812,
            "y" : 804
          },
          "b" : {
            "x" : 824,
            "y" : 816
          },
          "type" : "BOX",
          "empty" : true,
          "centre" : {
            "x" : 818,
            "y" : 810
          }
        }
      }
    } ]
  }, {
    "id" : 34123,
    "reactomeId" : 10346549,
    "displayName" : "SCF-beta-TrCP:phospho-Emi1 complexes",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 555,
      "y" : 826
    },
    "minX" : 457,
    "maxX" : 612,
    "minY" : 759,
    "maxY" : 854,
    "prop" : {
      "x" : 505,
      "y" : 799,
      "width" : 101,
      "height" : 55
    },
    "textPosition" : {
      "x" : 505,
      "y" : 805
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 606,
          "y" : 799
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 606,
          "y" : 799
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 34121,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 555,
          "y" : 796
        },
        "to" : {
          "x" : 557,
          "y" : 759
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 34121,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 502,
          "y" : 818
        },
        "to" : {
          "x" : 466,
          "y" : 812
        }
      }, {
        "from" : {
          "x" : 466,
          "y" : 812
        },
        "to" : {
          "x" : 461,
          "y" : 775
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 461,
          "y" : 771
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 461,
          "y" : 771
        }
      }
    } ]
  }, {
    "id" : 34124,
    "reactomeId" : 10346551,
    "displayName" : "SCF-associated multiubiquitinated Emi1complexes",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 354,
      "y" : 760
    },
    "minX" : 291,
    "maxX" : 423,
    "minY" : 729,
    "maxY" : 785,
    "prop" : {
      "x" : 291,
      "y" : 735,
      "width" : 126,
      "height" : 50
    },
    "textPosition" : {
      "x" : 291,
      "y" : 736
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 417,
          "y" : 735
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 417,
          "y" : 735
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 34121,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 34126,
    "reactomeId" : 10346418,
    "displayName" : "FZR1",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 589,
      "y" : 464
    },
    "minX" : 555,
    "maxX" : 617,
    "minY" : 442,
    "maxY" : 474,
    "prop" : {
      "x" : 568,
      "y" : 454,
      "width" : 43,
      "height" : 20
    },
    "textPosition" : {
      "x" : 569,
      "y" : 454
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 611,
          "y" : 454
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 611,
          "y" : 454
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 34125,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 573,
          "y" : 451
        },
        "to" : {
          "x" : 555,
          "y" : 442
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 34127,
    "reactomeId" : 29358,
    "displayName" : "ATP",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 521,
      "y" : 465
    },
    "minX" : 502,
    "maxX" : 555,
    "minY" : 442,
    "maxY" : 480,
    "prop" : {
      "x" : 502,
      "y" : 450,
      "width" : 38,
      "height" : 30
    },
    "textPosition" : {
      "x" : 505,
      "y" : 454
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 535,
          "y" : 455
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 535,
          "y" : 455
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 34125,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 543,
          "y" : 452
        },
        "to" : {
          "x" : 555,
          "y" : 442
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 34128,
    "reactomeId" : 113582,
    "displayName" : "ADP",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 510,
      "y" : 359
    },
    "minX" : 491,
    "maxX" : 556,
    "minY" : 343,
    "maxY" : 389,
    "prop" : {
      "x" : 491,
      "y" : 344,
      "width" : 39,
      "height" : 30
    },
    "textPosition" : {
      "x" : 494,
      "y" : 348
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 525,
          "y" : 349
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 525,
          "y" : 349
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 34125,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 533,
          "y" : 371
        },
        "to" : {
          "x" : 556,
          "y" : 389
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 541,
          "y" : 372
        },
        "b" : {
          "x" : 533,
          "y" : 371
        },
        "c" : {
          "x" : 536,
          "y" : 378
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 536,
          "y" : 378
        }
      }
    } ]
  }, {
    "id" : 34130,
    "reactomeId" : 10342808,
    "displayName" : "CDC20",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 500,
      "y" : 1391
    },
    "minX" : 433,
    "maxX" : 1433,
    "minY" : 1013,
    "maxY" : 1588,
    "prop" : {
      "x" : 475,
      "y" : 1380,
      "width" : 51,
      "height" : 22
    },
    "textPosition" : {
      "x" : 476,
      "y" : 1380
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 526,
          "y" : 1380
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 526,
          "y" : 1380
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 34179,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 507,
          "y" : 1405
        },
        "to" : {
          "x" : 626,
          "y" : 1588
        }
      }, {
        "from" : {
          "x" : 626,
          "y" : 1588
        },
        "to" : {
          "x" : 1320,
          "y" : 1582
        }
      }, {
        "from" : {
          "x" : 1320,
          "y" : 1582
        },
        "to" : {
          "x" : 1433,
          "y" : 1013
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 514,
          "y" : 1409
        },
        "b" : {
          "x" : 507,
          "y" : 1405
        },
        "c" : {
          "x" : 507,
          "y" : 1413
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 507,
          "y" : 1413
        }
      }
    }, {
      "edgeId" : 34129,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 480,
          "y" : 1405
        },
        "to" : {
          "x" : 433,
          "y" : 1429
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 34133,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 500,
          "y" : 1405
        },
        "to" : {
          "x" : 501,
          "y" : 1507
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 34131,
    "reactomeId" : 10342796,
    "displayName" : "LOC780876",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 447,
      "y" : 1468
    },
    "minX" : 414,
    "maxX" : 501,
    "minY" : 1429,
    "maxY" : 1507,
    "prop" : {
      "x" : 414,
      "y" : 1450,
      "width" : 66,
      "height" : 37
    },
    "textPosition" : {
      "x" : 415,
      "y" : 1451
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 480,
          "y" : 1450
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 480,
          "y" : 1450
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 34129,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 440,
          "y" : 1447
        },
        "to" : {
          "x" : 433,
          "y" : 1429
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 34133,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 472,
          "y" : 1490
        },
        "to" : {
          "x" : 501,
          "y" : 1507
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 34132,
    "reactomeId" : 10342880,
    "displayName" : "MAD2*CDC20 complex",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 326,
      "y" : 1434
    },
    "minX" : 280,
    "maxX" : 379,
    "minY" : 1410,
    "maxY" : 1452,
    "prop" : {
      "x" : 280,
      "y" : 1416,
      "width" : 93,
      "height" : 36
    },
    "textPosition" : {
      "x" : 280,
      "y" : 1417
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 373,
          "y" : 1416
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 373,
          "y" : 1416
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 34129,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 34134,
    "reactomeId" : 10342804,
    "displayName" : "BUB3",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 417,
      "y" : 1566
    },
    "minX" : 360,
    "maxX" : 501,
    "minY" : 1507,
    "maxY" : 1584,
    "prop" : {
      "x" : 360,
      "y" : 1548,
      "width" : 114,
      "height" : 36
    },
    "textPosition" : {
      "x" : 396,
      "y" : 1555
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 474,
          "y" : 1548
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 474,
          "y" : 1548
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 34133,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 442,
          "y" : 1545
        },
        "to" : {
          "x" : 501,
          "y" : 1507
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 34135,
    "reactomeId" : 10342800,
    "displayName" : "BUB1B",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 536,
      "y" : 1563
    },
    "minX" : 501,
    "maxX" : 569,
    "minY" : 1507,
    "maxY" : 1574,
    "prop" : {
      "x" : 510,
      "y" : 1552,
      "width" : 53,
      "height" : 22
    },
    "textPosition" : {
      "x" : 512,
      "y" : 1552
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 563,
          "y" : 1552
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 563,
          "y" : 1552
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 34133,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 529,
          "y" : 1549
        },
        "to" : {
          "x" : 501,
          "y" : 1507
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 34136,
    "reactomeId" : 10342810,
    "displayName" : "Mitotic checkpoint complex",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 648,
      "y" : 1399
    },
    "minX" : 595,
    "maxX" : 708,
    "minY" : 1303,
    "maxY" : 1424,
    "prop" : {
      "x" : 595,
      "y" : 1374,
      "width" : 107,
      "height" : 50
    },
    "textPosition" : {
      "x" : 608,
      "y" : 1375
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 702,
          "y" : 1374
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 702,
          "y" : 1374
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 34133,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 34137,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 642,
          "y" : 1371
        },
        "to" : {
          "x" : 627,
          "y" : 1303
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 34138,
    "reactomeId" : 10333422,
    "displayName" : "phosphorylated anaphase promoting complex (APC/C)",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 535,
      "y" : 1308
    },
    "minX" : 80,
    "maxX" : 1433,
    "minY" : 1013,
    "maxY" : 1566,
    "prop" : {
      "x" : 465,
      "y" : 1282,
      "width" : 141,
      "height" : 53
    },
    "textPosition" : {
      "x" : 464,
      "y" : 1286
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 606,
          "y" : 1282
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 606,
          "y" : 1282
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 34179,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 546,
          "y" : 1338
        },
        "to" : {
          "x" : 643,
          "y" : 1566
        }
      }, {
        "from" : {
          "x" : 643,
          "y" : 1566
        },
        "to" : {
          "x" : 1291,
          "y" : 1562
        }
      }, {
        "from" : {
          "x" : 1291,
          "y" : 1562
        },
        "to" : {
          "x" : 1433,
          "y" : 1013
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 552,
          "y" : 1343
        },
        "b" : {
          "x" : 546,
          "y" : 1338
        },
        "c" : {
          "x" : 545,
          "y" : 1346
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 545,
          "y" : 1346
        }
      }
    }, {
      "edgeId" : 34180,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 462,
          "y" : 1307
        },
        "to" : {
          "x" : 80,
          "y" : 1307
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 34137,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 609,
          "y" : 1304
        },
        "to" : {
          "x" : 627,
          "y" : 1303
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 34139,
    "reactomeId" : 10342876,
    "displayName" : "MCC:APC/C complex",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 781,
      "y" : 1300
    },
    "minX" : 708,
    "maxX" : 917,
    "minY" : 1192,
    "maxY" : 1396,
    "prop" : {
      "x" : 708,
      "y" : 1288,
      "width" : 147,
      "height" : 25
    },
    "textPosition" : {
      "x" : 717,
      "y" : 1292
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 855,
          "y" : 1288
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 855,
          "y" : 1288
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 34196,
      "type" : "INPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 34137,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 34142,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 811,
          "y" : 1316
        },
        "to" : {
          "x" : 917,
          "y" : 1356
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 34145,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 789,
          "y" : 1285
        },
        "to" : {
          "x" : 804,
          "y" : 1267
        }
      }, {
        "from" : {
          "x" : 804,
          "y" : 1267
        },
        "to" : {
          "x" : 805,
          "y" : 1255
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 805,
          "y" : 1251
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 805,
          "y" : 1251
        }
      }
    }, {
      "edgeId" : 34148,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 779,
          "y" : 1285
        },
        "to" : {
          "x" : 766,
          "y" : 1192
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 774,
          "y" : 1279
        },
        "b" : {
          "x" : 779,
          "y" : 1285
        },
        "c" : {
          "x" : 782,
          "y" : 1278
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 782,
          "y" : 1278
        }
      }
    }, {
      "edgeId" : 34151,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 770,
          "y" : 1316
        },
        "to" : {
          "x" : 745,
          "y" : 1341
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 34157,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 796,
          "y" : 1316
        },
        "to" : {
          "x" : 897,
          "y" : 1396
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 804,
          "y" : 1317
        },
        "b" : {
          "x" : 796,
          "y" : 1316
        },
        "c" : {
          "x" : 799,
          "y" : 1323
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 799,
          "y" : 1323
        }
      }
    } ]
  }, {
    "id" : 34143,
    "reactomeId" : 10346449,
    "displayName" : "Cyclin A:phospho-Cdc2(Thr 161) complex",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 1062,
      "y" : 1424
    },
    "minX" : 917,
    "maxX" : 1128,
    "minY" : 1356,
    "maxY" : 1449,
    "prop" : {
      "x" : 1003,
      "y" : 1399,
      "width" : 119,
      "height" : 50
    },
    "textPosition" : {
      "x" : 1003,
      "y" : 1400
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1122,
          "y" : 1399
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1122,
          "y" : 1399
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 34142,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1008,
          "y" : 1396
        },
        "to" : {
          "x" : 917,
          "y" : 1356
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 34144,
    "reactomeId" : 10346451,
    "displayName" : "Cdc2:Cyclin A:MCC:APC/C complex",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 1053,
      "y" : 1354
    },
    "minX" : 837,
    "maxX" : 1122,
    "minY" : 1219,
    "maxY" : 1372,
    "prop" : {
      "x" : 991,
      "y" : 1336,
      "width" : 125,
      "height" : 36
    },
    "textPosition" : {
      "x" : 991,
      "y" : 1337
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1116,
          "y" : 1336
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1116,
          "y" : 1336
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 34142,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 34145,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1024,
          "y" : 1333
        },
        "to" : {
          "x" : 837,
          "y" : 1219
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 34146,
    "reactomeId" : 10333291,
    "displayName" : "Ub",
    "schemaClass" : "DefinedSet",
    "renderableClass" : "EntitySet",
    "position" : {
      "x" : 905,
      "y" : 1193
    },
    "minX" : 766,
    "maxX" : 941,
    "minY" : 1182,
    "maxY" : 1220,
    "prop" : {
      "x" : 869,
      "y" : 1182,
      "width" : 72,
      "height" : 22
    },
    "textPosition" : {
      "x" : 892,
      "y" : 1182
    },
    "connectors" : [ {
      "edgeId" : 34145,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 876,
          "y" : 1210
        },
        "to" : {
          "x" : 837,
          "y" : 1219
        }
      } ],
      "stoichiometry" : {
        "value" : 4,
        "shape" : {
          "a" : {
            "x" : 850,
            "y" : 1208
          },
          "b" : {
            "x" : 862,
            "y" : 1220
          },
          "type" : "BOX",
          "empty" : true,
          "centre" : {
            "x" : 856,
            "y" : 1214
          }
        }
      }
    }, {
      "edgeId" : 34148,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 863,
          "y" : 1192
        },
        "to" : {
          "x" : 766,
          "y" : 1192
        }
      } ],
      "stoichiometry" : {
        "value" : 4,
        "shape" : {
          "a" : {
            "x" : 808,
            "y" : 1186
          },
          "b" : {
            "x" : 820,
            "y" : 1198
          },
          "type" : "BOX",
          "empty" : true,
          "centre" : {
            "x" : 814,
            "y" : 1192
          }
        }
      },
      "endShape" : {
        "a" : {
          "x" : 856,
          "y" : 1196
        },
        "b" : {
          "x" : 863,
          "y" : 1192
        },
        "c" : {
          "x" : 856,
          "y" : 1188
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 856,
          "y" : 1188
        }
      }
    } ]
  }, {
    "id" : 34147,
    "reactomeId" : 10346453,
    "displayName" : "multiubiquitinated Cyclin A associated with MCC:APC/C complex",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 606,
      "y" : 1195
    },
    "minX" : 514,
    "maxX" : 705,
    "minY" : 1163,
    "maxY" : 1221,
    "prop" : {
      "x" : 514,
      "y" : 1169,
      "width" : 185,
      "height" : 52
    },
    "textPosition" : {
      "x" : 516,
      "y" : 1172
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 699,
          "y" : 1169
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 699,
          "y" : 1169
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 34145,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 34148,
      "type" : "INPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 34149,
    "reactomeId" : 10341008,
    "displayName" : "phospho-p-T161-CDK1",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 810,
      "y" : 1126
    },
    "minX" : 760,
    "maxX" : 1027,
    "minY" : 1106,
    "maxY" : 1192,
    "prop" : {
      "x" : 760,
      "y" : 1115,
      "width" : 101,
      "height" : 22
    },
    "textPosition" : {
      "x" : 771,
      "y" : 1109
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 861,
          "y" : 1115
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 861,
          "y" : 1115
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 34148,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 802,
          "y" : 1140
        },
        "to" : {
          "x" : 766,
          "y" : 1192
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 801,
          "y" : 1148
        },
        "b" : {
          "x" : 802,
          "y" : 1140
        },
        "c" : {
          "x" : 795,
          "y" : 1143
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 795,
          "y" : 1143
        }
      }
    }, {
      "edgeId" : 34165,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 864,
          "y" : 1121
        },
        "to" : {
          "x" : 1027,
          "y" : 1106
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 871,
          "y" : 1116
        },
        "b" : {
          "x" : 864,
          "y" : 1121
        },
        "c" : {
          "x" : 871,
          "y" : 1124
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 871,
          "y" : 1124
        }
      }
    } ]
  }, {
    "id" : 34150,
    "reactomeId" : 10333339,
    "displayName" : "26S proteasome",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 356,
      "y" : 1061
    },
    "minX" : 263,
    "maxX" : 752,
    "minY" : 968,
    "maxY" : 1185,
    "prop" : {
      "x" : 300,
      "y" : 1050,
      "width" : 113,
      "height" : 22
    },
    "textPosition" : {
      "x" : 300,
      "y" : 1051
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 413,
          "y" : 1050
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 413,
          "y" : 1050
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 34188,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 332,
          "y" : 1075
        },
        "to" : {
          "x" : 266,
          "y" : 1104
        }
      }, {
        "from" : {
          "x" : 266,
          "y" : 1104
        },
        "to" : {
          "x" : 267,
          "y" : 1123
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 267,
          "y" : 1127
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 267,
          "y" : 1127
        }
      }
    }, {
      "edgeId" : 34148,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 397,
          "y" : 1075
        },
        "to" : {
          "x" : 736,
          "y" : 1161
        }
      }, {
        "from" : {
          "x" : 736,
          "y" : 1161
        },
        "to" : {
          "x" : 737,
          "y" : 1177
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 737,
          "y" : 1181
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 737,
          "y" : 1181
        }
      }
    }, {
      "edgeId" : 34172,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 404,
          "y" : 1047
        },
        "to" : {
          "x" : 744,
          "y" : 972
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 748,
          "y" : 972
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 748,
          "y" : 972
        }
      }
    } ]
  }, {
    "id" : 34152,
    "reactomeId" : 10347650,
    "displayName" : "NEK2",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 693,
      "y" : 1337
    },
    "minX" : 666,
    "maxX" : 745,
    "minY" : 1321,
    "maxY" : 1347,
    "prop" : {
      "x" : 666,
      "y" : 1327,
      "width" : 55,
      "height" : 20
    },
    "textPosition" : {
      "x" : 673,
      "y" : 1327
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 721,
          "y" : 1327
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 721,
          "y" : 1327
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 34151,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 724,
          "y" : 1339
        },
        "to" : {
          "x" : 745,
          "y" : 1341
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 34153,
    "reactomeId" : 10347652,
    "displayName" : "Nek2A:MCC:APC/C complex",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 745,
      "y" : 1501
    },
    "minX" : 697,
    "maxX" : 906,
    "minY" : 1469,
    "maxY" : 1533,
    "prop" : {
      "x" : 697,
      "y" : 1475,
      "width" : 97,
      "height" : 53
    },
    "textPosition" : {
      "x" : 704,
      "y" : 1479
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 794,
          "y" : 1475
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 794,
          "y" : 1475
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 34151,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 34154,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 797,
          "y" : 1501
        },
        "to" : {
          "x" : 853,
          "y" : 1502
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 34154,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 797,
          "y" : 1510
        },
        "to" : {
          "x" : 902,
          "y" : 1533
        }
      }, {
        "from" : {
          "x" : 902,
          "y" : 1533
        },
        "to" : {
          "x" : 902,
          "y" : 1517
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 902,
          "y" : 1513
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 902,
          "y" : 1513
        }
      }
    } ]
  }, {
    "id" : 34155,
    "reactomeId" : 10333291,
    "displayName" : "Ub",
    "schemaClass" : "DefinedSet",
    "renderableClass" : "EntitySet",
    "position" : {
      "x" : 828,
      "y" : 1430
    },
    "minX" : 793,
    "maxX" : 897,
    "minY" : 1396,
    "maxY" : 1502,
    "prop" : {
      "x" : 793,
      "y" : 1419,
      "width" : 70,
      "height" : 22
    },
    "textPosition" : {
      "x" : 815,
      "y" : 1419
    },
    "connectors" : [ {
      "edgeId" : 34154,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 831,
          "y" : 1447
        },
        "to" : {
          "x" : 853,
          "y" : 1502
        }
      } ],
      "stoichiometry" : {
        "value" : 3,
        "shape" : {
          "a" : {
            "x" : 836,
            "y" : 1468
          },
          "b" : {
            "x" : 848,
            "y" : 1480
          },
          "type" : "BOX",
          "empty" : true,
          "centre" : {
            "x" : 842,
            "y" : 1474
          }
        }
      }
    }, {
      "edgeId" : 34157,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 850,
          "y" : 1413
        },
        "to" : {
          "x" : 897,
          "y" : 1396
        }
      } ],
      "stoichiometry" : {
        "value" : 3,
        "shape" : {
          "a" : {
            "x" : 867,
            "y" : 1398
          },
          "b" : {
            "x" : 879,
            "y" : 1410
          },
          "type" : "BOX",
          "empty" : true,
          "centre" : {
            "x" : 873,
            "y" : 1404
          }
        }
      },
      "endShape" : {
        "a" : {
          "x" : 855,
          "y" : 1407
        },
        "b" : {
          "x" : 850,
          "y" : 1413
        },
        "c" : {
          "x" : 858,
          "y" : 1414
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 858,
          "y" : 1414
        }
      }
    } ]
  }, {
    "id" : 34156,
    "reactomeId" : 10347656,
    "displayName" : "Multiubiquitinated Nek2A",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 1005,
      "y" : 1505
    },
    "minX" : 950,
    "maxX" : 1067,
    "minY" : 1481,
    "maxY" : 1523,
    "prop" : {
      "x" : 950,
      "y" : 1487,
      "width" : 111,
      "height" : 36
    },
    "textPosition" : {
      "x" : 953,
      "y" : 1488
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1061,
          "y" : 1487
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1061,
          "y" : 1487
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 34154,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 34157,
      "type" : "INPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 34159,
    "reactomeId" : 10345726,
    "displayName" : "CCNB1:p-T161-CDK1",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 1327,
      "y" : 1047
    },
    "minX" : 1246,
    "maxX" : 1414,
    "minY" : 1023,
    "maxY" : 1106,
    "prop" : {
      "x" : 1246,
      "y" : 1029,
      "width" : 162,
      "height" : 36
    },
    "textPosition" : {
      "x" : 1261,
      "y" : 1044
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1408,
          "y" : 1029
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1408,
          "y" : 1029
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 34158,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1312,
          "y" : 1068
        },
        "to" : {
          "x" : 1280,
          "y" : 1106
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 34160,
    "reactomeId" : 10346476,
    "displayName" : "CDC20:p-APC/C",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 1157,
      "y" : 1000
    },
    "minX" : 760,
    "maxX" : 1280,
    "minY" : 955,
    "maxY" : 1300,
    "prop" : {
      "x" : 1106,
      "y" : 982,
      "width" : 103,
      "height" : 36
    },
    "textPosition" : {
      "x" : 1107,
      "y" : 997
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1209,
          "y" : 982
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1209,
          "y" : 982
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 34179,
      "type" : "INPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 34196,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 1157,
          "y" : 1021
        },
        "to" : {
          "x" : 1160,
          "y" : 1265
        }
      }, {
        "from" : {
          "x" : 1160,
          "y" : 1265
        },
        "to" : {
          "x" : 1161,
          "y" : 1300
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 1161,
          "y" : 1028
        },
        "b" : {
          "x" : 1157,
          "y" : 1021
        },
        "c" : {
          "x" : 1153,
          "y" : 1028
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 1153,
          "y" : 1028
        }
      }
    }, {
      "edgeId" : 34158,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1177,
          "y" : 1021
        },
        "to" : {
          "x" : 1280,
          "y" : 1106
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 34165,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 1134,
          "y" : 1021
        },
        "to" : {
          "x" : 1027,
          "y" : 1106
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 1131,
          "y" : 1028
        },
        "b" : {
          "x" : 1134,
          "y" : 1021
        },
        "c" : {
          "x" : 1126,
          "y" : 1022
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 1126,
          "y" : 1022
        }
      }
    }, {
      "edgeId" : 34167,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1167,
          "y" : 979
        },
        "to" : {
          "x" : 1183,
          "y" : 955
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 34172,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 1103,
          "y" : 999
        },
        "to" : {
          "x" : 760,
          "y" : 997
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 1096,
          "y" : 1003
        },
        "b" : {
          "x" : 1103,
          "y" : 999
        },
        "c" : {
          "x" : 1096,
          "y" : 995
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 1096,
          "y" : 995
        }
      }
    } ]
  }, {
    "id" : 34161,
    "reactomeId" : 10346478,
    "displayName" : "Cdc20:phospho-APC/C:Cyclin B:Cdc2 complex",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 1295,
      "y" : 1216
    },
    "minX" : 1150,
    "maxX" : 1367,
    "minY" : 1173,
    "maxY" : 1241,
    "prop" : {
      "x" : 1230,
      "y" : 1191,
      "width" : 131,
      "height" : 50
    },
    "textPosition" : {
      "x" : 1229,
      "y" : 1192
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1361,
          "y" : 1191
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1361,
          "y" : 1191
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 34158,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 34162,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1227,
          "y" : 1215
        },
        "to" : {
          "x" : 1192,
          "y" : 1215
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 34162,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 1233,
          "y" : 1188
        },
        "to" : {
          "x" : 1190,
          "y" : 1173
        }
      }, {
        "from" : {
          "x" : 1190,
          "y" : 1173
        },
        "to" : {
          "x" : 1157,
          "y" : 1205
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 1154,
          "y" : 1208
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1154,
          "y" : 1208
        }
      }
    } ]
  }, {
    "id" : 34163,
    "reactomeId" : 10333291,
    "displayName" : "Ub",
    "schemaClass" : "DefinedSet",
    "renderableClass" : "EntitySet",
    "position" : {
      "x" : 1237,
      "y" : 1296
    },
    "minX" : 1192,
    "maxX" : 1275,
    "minY" : 1215,
    "maxY" : 1307,
    "prop" : {
      "x" : 1200,
      "y" : 1285,
      "width" : 75,
      "height" : 22
    },
    "textPosition" : {
      "x" : 1225,
      "y" : 1285
    },
    "connectors" : [ {
      "edgeId" : 34162,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1230,
          "y" : 1279
        },
        "to" : {
          "x" : 1192,
          "y" : 1215
        }
      } ],
      "stoichiometry" : {
        "value" : 4,
        "shape" : {
          "a" : {
            "x" : 1205,
            "y" : 1241
          },
          "b" : {
            "x" : 1217,
            "y" : 1253
          },
          "type" : "BOX",
          "empty" : true,
          "centre" : {
            "x" : 1211,
            "y" : 1247
          }
        }
      }
    } ]
  }, {
    "id" : 34164,
    "reactomeId" : 10346523,
    "displayName" : "multiubiquitinated Cyclin B:Cdc2:Cdc20:phospho-APC/C complex",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 1032,
      "y" : 1218
    },
    "minX" : 967,
    "maxX" : 1103,
    "minY" : 1180,
    "maxY" : 1250,
    "prop" : {
      "x" : 967,
      "y" : 1186,
      "width" : 130,
      "height" : 64
    },
    "textPosition" : {
      "x" : 969,
      "y" : 1187
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1097,
          "y" : 1186
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1097,
          "y" : 1186
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 34162,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 34165,
      "type" : "INPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 34166,
    "reactomeId" : 10333291,
    "displayName" : "Ub",
    "schemaClass" : "DefinedSet",
    "renderableClass" : "EntitySet",
    "position" : {
      "x" : 761,
      "y" : 1060
    },
    "minX" : 721,
    "maxX" : 1027,
    "minY" : 997,
    "maxY" : 1106,
    "prop" : {
      "x" : 721,
      "y" : 1049,
      "width" : 81,
      "height" : 22
    },
    "textPosition" : {
      "x" : 749,
      "y" : 1049
    },
    "connectors" : [ {
      "edgeId" : 34165,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 808,
          "y" : 1067
        },
        "to" : {
          "x" : 1027,
          "y" : 1106
        }
      } ],
      "stoichiometry" : {
        "value" : 4,
        "shape" : {
          "a" : {
            "x" : 911,
            "y" : 1080
          },
          "b" : {
            "x" : 923,
            "y" : 1092
          },
          "type" : "BOX",
          "empty" : true,
          "centre" : {
            "x" : 917,
            "y" : 1086
          }
        }
      },
      "endShape" : {
        "a" : {
          "x" : 816,
          "y" : 1064
        },
        "b" : {
          "x" : 808,
          "y" : 1067
        },
        "c" : {
          "x" : 814,
          "y" : 1072
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 814,
          "y" : 1072
        }
      }
    }, {
      "edgeId" : 34172,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 760,
          "y" : 1043
        },
        "to" : {
          "x" : 760,
          "y" : 997
        }
      } ],
      "stoichiometry" : {
        "value" : 4,
        "shape" : {
          "a" : {
            "x" : 754,
            "y" : 1014
          },
          "b" : {
            "x" : 766,
            "y" : 1026
          },
          "type" : "BOX",
          "empty" : true,
          "centre" : {
            "x" : 760,
            "y" : 1020
          }
        }
      },
      "endShape" : {
        "a" : {
          "x" : 756,
          "y" : 1036
        },
        "b" : {
          "x" : 760,
          "y" : 1043
        },
        "c" : {
          "x" : 764,
          "y" : 1036
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 764,
          "y" : 1036
        }
      }
    } ]
  }, {
    "id" : 34168,
    "reactomeId" : 10346431,
    "displayName" : "PTTG1",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 1263,
      "y" : 970
    },
    "minX" : 1183,
    "maxX" : 1296,
    "minY" : 953,
    "maxY" : 981,
    "prop" : {
      "x" : 1236,
      "y" : 959,
      "width" : 54,
      "height" : 22
    },
    "textPosition" : {
      "x" : 1239,
      "y" : 959
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1290,
          "y" : 959
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1290,
          "y" : 959
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 34167,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1233,
          "y" : 964
        },
        "to" : {
          "x" : 1183,
          "y" : 955
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 34169,
    "reactomeId" : 10346482,
    "displayName" : "CDC20:p-APC/C:PTTG1",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 1181,
      "y" : 859
    },
    "minX" : 895,
    "maxX" : 1242,
    "minY" : 828,
    "maxY" : 908,
    "prop" : {
      "x" : 1127,
      "y" : 834,
      "width" : 109,
      "height" : 50
    },
    "textPosition" : {
      "x" : 1129,
      "y" : 849
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1236,
          "y" : 834
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1236,
          "y" : 834
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 34167,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 34170,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1124,
          "y" : 855
        },
        "to" : {
          "x" : 929,
          "y" : 842
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 34170,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 1124,
          "y" : 870
        },
        "to" : {
          "x" : 947,
          "y" : 908
        }
      }, {
        "from" : {
          "x" : 947,
          "y" : 908
        },
        "to" : {
          "x" : 903,
          "y" : 873
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 899,
          "y" : 870
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 899,
          "y" : 870
        }
      }
    } ]
  }, {
    "id" : 34171,
    "reactomeId" : 10346518,
    "displayName" : "CDC20:pAPC/C:K11polyUb-PTTG1",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 759,
      "y" : 864
    },
    "minX" : 719,
    "maxX" : 805,
    "minY" : 826,
    "maxY" : 896,
    "prop" : {
      "x" : 719,
      "y" : 832,
      "width" : 80,
      "height" : 64
    },
    "textPosition" : {
      "x" : 720,
      "y" : 833
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 799,
          "y" : 832
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 799,
          "y" : 832
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 34170,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 34172,
      "type" : "INPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 34174,
    "reactomeId" : 10346500,
    "displayName" : "phospho-FZR1",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 135,
      "y" : 1612
    },
    "minX" : 83,
    "maxX" : 182,
    "minY" : 1565,
    "maxY" : 1629,
    "prop" : {
      "x" : 95,
      "y" : 1595,
      "width" : 81,
      "height" : 34
    },
    "textPosition" : {
      "x" : 102,
      "y" : 1595
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 176,
          "y" : 1595
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 176,
          "y" : 1595
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 34173,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 116,
          "y" : 1592
        },
        "to" : {
          "x" : 83,
          "y" : 1565
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 34175,
    "reactomeId" : 29356,
    "displayName" : "H2O",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 56,
      "y" : 1612
    },
    "minX" : 36,
    "maxX" : 83,
    "minY" : 1565,
    "maxY" : 1627,
    "prop" : {
      "x" : 36,
      "y" : 1597,
      "width" : 41,
      "height" : 30
    },
    "textPosition" : {
      "x" : 39,
      "y" : 1601
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 72,
          "y" : 1602
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 72,
          "y" : 1602
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 34173,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 64,
          "y" : 1594
        },
        "to" : {
          "x" : 83,
          "y" : 1565
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ],
    "trivial" : true
  } ],
  "edges" : [ {
    "id" : 34179,
    "reactomeId" : 10346571,
    "displayName" : "Dissociation of Cdc20 from APC/C complex",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 1238,
      "y" : 1013
    },
    "minX" : 1212,
    "maxX" : 1433,
    "minY" : 1007,
    "maxY" : 1019,
    "reactionType" : "dissociation",
    "segments" : [ {
      "from" : {
        "x" : 1212,
        "y" : 1008
      },
      "to" : {
        "x" : 1238,
        "y" : 1013
      }
    }, {
      "from" : {
        "x" : 1238,
        "y" : 1013
      },
      "to" : {
        "x" : 1433,
        "y" : 1013
      }
    } ],
    "reactionShape" : {
      "c" : {
        "x" : 1238,
        "y" : 1013
      },
      "r" : 5,
      "r1" : 3,
      "type" : "DOUBLE_CIRCLE",
      "empty" : true,
      "centre" : {
        "x" : 1238,
        "y" : 1013
      }
    },
    "inputs" : [ {
      "id" : 34160
    } ],
    "outputs" : [ {
      "id" : 34130,
      "points" : [ {
        "x" : 507,
        "y" : 1405
      }, {
        "x" : 626,
        "y" : 1588
      }, {
        "x" : 1320,
        "y" : 1582
      } ]
    }, {
      "id" : 34138,
      "points" : [ {
        "x" : 546,
        "y" : 1338
      }, {
        "x" : 643,
        "y" : 1566
      }, {
        "x" : 1291,
        "y" : 1562
      } ]
    } ]
  }, {
    "id" : 34116,
    "reactomeId" : 10346564,
    "displayName" : "Phosphorylation of the Emi1 DSGxxS degron by Plk1",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 334,
      "y" : 616
    },
    "minX" : 305,
    "maxX" : 378,
    "minY" : 610,
    "maxY" : 622,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 305,
        "y" : 616
      },
      "to" : {
        "x" : 334,
        "y" : 616
      }
    }, {
      "from" : {
        "x" : 334,
        "y" : 616
      },
      "to" : {
        "x" : 378,
        "y" : 616
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 328,
        "y" : 610
      },
      "b" : {
        "x" : 340,
        "y" : 622
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 334,
        "y" : 616
      }
    },
    "inputs" : [ {
      "id" : 34117,
      "points" : [ {
        "x" : 244,
        "y" : 630
      } ],
      "stoichiometry" : 2
    }, {
      "id" : 34112,
      "points" : [ {
        "x" : 264,
        "y" : 593
      } ]
    } ],
    "outputs" : [ {
      "id" : 34118,
      "points" : [ {
        "x" : 416,
        "y" : 654
      } ],
      "stoichiometry" : 2
    }, {
      "id" : 34119,
      "points" : [ {
        "x" : 415,
        "y" : 609
      } ]
    } ],
    "catalysts" : [ {
      "id" : 34120,
      "points" : [ {
        "x" : 227,
        "y" : 455
      }, {
        "x" : 301,
        "y" : 479
      } ]
    } ]
  }, {
    "id" : 34180,
    "reactomeId" : 10346416,
    "displayName" : "Association of Cdh1 with the APC/C",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 81,
      "y" : 1212
    },
    "minX" : 75,
    "maxX" : 115,
    "minY" : 1164,
    "maxY" : 1307,
    "reactionType" : "binding",
    "segments" : [ {
      "from" : {
        "x" : 80,
        "y" : 1307
      },
      "to" : {
        "x" : 81,
        "y" : 1212
      }
    }, {
      "from" : {
        "x" : 81,
        "y" : 1212
      },
      "to" : {
        "x" : 115,
        "y" : 1164
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 114,
        "y" : 1172
      },
      "b" : {
        "x" : 115,
        "y" : 1164
      },
      "c" : {
        "x" : 108,
        "y" : 1167
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 108,
        "y" : 1167
      }
    },
    "reactionShape" : {
      "c" : {
        "x" : 81,
        "y" : 1212
      },
      "r" : 5,
      "type" : "CIRCLE",
      "centre" : {
        "x" : 81,
        "y" : 1212
      }
    },
    "inputs" : [ {
      "id" : 34138,
      "points" : [ {
        "x" : 462,
        "y" : 1307
      } ]
    }, {
      "id" : 34177,
      "points" : [ {
        "x" : 156,
        "y" : 1453
      } ]
    } ],
    "outputs" : [ {
      "id" : 34181
    } ]
  }, {
    "id" : 34182,
    "reactomeId" : 10346441,
    "displayName" : "Association of cell cycle proteins with the APC/C:Cdh1 complex",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 188,
      "y" : 1219
    },
    "minX" : 164,
    "maxX" : 210,
    "minY" : 1213,
    "maxY" : 1225,
    "reactionType" : "binding",
    "segments" : [ {
      "from" : {
        "x" : 164,
        "y" : 1218
      },
      "to" : {
        "x" : 188,
        "y" : 1219
      }
    }, {
      "from" : {
        "x" : 188,
        "y" : 1219
      },
      "to" : {
        "x" : 210,
        "y" : 1219
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 203,
        "y" : 1223
      },
      "b" : {
        "x" : 210,
        "y" : 1219
      },
      "c" : {
        "x" : 203,
        "y" : 1215
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 203,
        "y" : 1215
      }
    },
    "reactionShape" : {
      "c" : {
        "x" : 188,
        "y" : 1219
      },
      "r" : 5,
      "type" : "CIRCLE",
      "centre" : {
        "x" : 188,
        "y" : 1219
      }
    },
    "inputs" : [ {
      "id" : 34181,
      "points" : [ {
        "x" : 135,
        "y" : 1164
      } ]
    }, {
      "id" : 34183,
      "points" : [ {
        "x" : 186,
        "y" : 1322
      } ]
    } ],
    "outputs" : [ {
      "id" : 34184
    } ]
  }, {
    "id" : 34185,
    "reactomeId" : 10346567,
    "displayName" : "Ubiquitination of cell cycle proteins targeted by the APC/C:Cdh1complex",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 358,
      "y" : 1195
    },
    "minX" : 352,
    "maxX" : 364,
    "minY" : 1174,
    "maxY" : 1220,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 358,
        "y" : 1220
      },
      "to" : {
        "x" : 358,
        "y" : 1195
      }
    }, {
      "from" : {
        "x" : 358,
        "y" : 1195
      },
      "to" : {
        "x" : 358,
        "y" : 1174
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 362,
        "y" : 1181
      },
      "b" : {
        "x" : 358,
        "y" : 1174
      },
      "c" : {
        "x" : 354,
        "y" : 1181
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 354,
        "y" : 1181
      }
    },
    "reactionShape" : {
      "a" : {
        "x" : 352,
        "y" : 1189
      },
      "b" : {
        "x" : 364,
        "y" : 1201
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 358,
        "y" : 1195
      }
    },
    "inputs" : [ {
      "id" : 34184,
      "points" : [ {
        "x" : 312,
        "y" : 1220
      } ]
    }, {
      "id" : 34186,
      "points" : [ {
        "x" : 359,
        "y" : 1264
      } ],
      "stoichiometry" : 4
    } ],
    "outputs" : [ {
      "id" : 34187
    } ],
    "catalysts" : [ {
      "id" : 34184,
      "points" : [ {
        "x" : 312,
        "y" : 1201
      }, {
        "x" : 327,
        "y" : 1195
      } ]
    } ]
  }, {
    "id" : 34121,
    "reactomeId" : 10346554,
    "displayName" : "Ubiquitination of Emi1 by SCF-beta-TrCP",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 459,
      "y" : 759
    },
    "minX" : 420,
    "maxX" : 557,
    "minY" : 753,
    "maxY" : 765,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 557,
        "y" : 759
      },
      "to" : {
        "x" : 459,
        "y" : 759
      }
    }, {
      "from" : {
        "x" : 459,
        "y" : 759
      },
      "to" : {
        "x" : 420,
        "y" : 759
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 427,
        "y" : 755
      },
      "b" : {
        "x" : 420,
        "y" : 759
      },
      "c" : {
        "x" : 427,
        "y" : 763
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 427,
        "y" : 763
      }
    },
    "reactionShape" : {
      "a" : {
        "x" : 453,
        "y" : 753
      },
      "b" : {
        "x" : 465,
        "y" : 765
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 459,
        "y" : 759
      }
    },
    "inputs" : [ {
      "id" : 34122,
      "points" : [ {
        "x" : 631,
        "y" : 760
      } ],
      "stoichiometry" : 3
    }, {
      "id" : 34123,
      "points" : [ {
        "x" : 555,
        "y" : 796
      } ]
    } ],
    "outputs" : [ {
      "id" : 34124
    } ],
    "catalysts" : [ {
      "id" : 34123,
      "points" : [ {
        "x" : 502,
        "y" : 818
      }, {
        "x" : 466,
        "y" : 812
      } ]
    } ]
  }, {
    "id" : 34188,
    "reactomeId" : 10346460,
    "displayName" : "Degradation of multiubiquitinated cell cycle proteins",
    "schemaClass" : "BlackBoxEvent",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 267,
      "y" : 1139
    },
    "minX" : 239,
    "maxX" : 289,
    "minY" : 1133,
    "maxY" : 1145,
    "reactionType" : "omitted",
    "segments" : [ {
      "from" : {
        "x" : 289,
        "y" : 1139
      },
      "to" : {
        "x" : 267,
        "y" : 1139
      }
    }, {
      "from" : {
        "x" : 267,
        "y" : 1139
      },
      "to" : {
        "x" : 239,
        "y" : 1138
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 261,
        "y" : 1133
      },
      "b" : {
        "x" : 273,
        "y" : 1145
      },
      "s" : "\\\\",
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 267,
        "y" : 1139
      }
    },
    "inputs" : [ {
      "id" : 34187
    } ],
    "outputs" : [ {
      "id" : 34181,
      "points" : [ {
        "x" : 184,
        "y" : 1140
      } ]
    }, {
      "id" : 34189,
      "points" : [ {
        "x" : 227,
        "y" : 1098
      } ],
      "stoichiometry" : 4
    } ],
    "catalysts" : [ {
      "id" : 34150,
      "points" : [ {
        "x" : 332,
        "y" : 1075
      }, {
        "x" : 266,
        "y" : 1104
      } ]
    } ]
  }, {
    "id" : 34125,
    "reactomeId" : 10346584,
    "displayName" : "Phosphorylation of Cdh1 by Cyclin B1:Cdc2",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 555,
      "y" : 416
    },
    "minX" : 549,
    "maxX" : 561,
    "minY" : 389,
    "maxY" : 442,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 555,
        "y" : 442
      },
      "to" : {
        "x" : 555,
        "y" : 416
      }
    }, {
      "from" : {
        "x" : 555,
        "y" : 416
      },
      "to" : {
        "x" : 556,
        "y" : 389
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 549,
        "y" : 410
      },
      "b" : {
        "x" : 561,
        "y" : 422
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 555,
        "y" : 416
      }
    },
    "inputs" : [ {
      "id" : 34126,
      "points" : [ {
        "x" : 573,
        "y" : 451
      } ]
    }, {
      "id" : 34127,
      "points" : [ {
        "x" : 543,
        "y" : 452
      } ]
    } ],
    "outputs" : [ {
      "id" : 34128,
      "points" : [ {
        "x" : 533,
        "y" : 371
      } ]
    }, {
      "id" : 34102,
      "points" : [ {
        "x" : 612,
        "y" : 367
      } ]
    } ],
    "catalysts" : [ {
      "id" : 34115,
      "points" : [ {
        "x" : 409,
        "y" : 418
      } ]
    } ]
  }, {
    "id" : 34190,
    "reactomeId" : 10346412,
    "displayName" : "Multiubiquitination of APC/C-associated Cdh1",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 928,
      "y" : 317
    },
    "minX" : 922,
    "maxX" : 934,
    "minY" : 280,
    "maxY" : 369,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 928,
        "y" : 369
      },
      "to" : {
        "x" : 928,
        "y" : 317
      }
    }, {
      "from" : {
        "x" : 928,
        "y" : 317
      },
      "to" : {
        "x" : 928,
        "y" : 280
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 932,
        "y" : 287
      },
      "b" : {
        "x" : 928,
        "y" : 280
      },
      "c" : {
        "x" : 924,
        "y" : 287
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 924,
        "y" : 287
      }
    },
    "reactionShape" : {
      "a" : {
        "x" : 922,
        "y" : 311
      },
      "b" : {
        "x" : 934,
        "y" : 323
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 928,
        "y" : 317
      }
    },
    "inputs" : [ {
      "id" : 34191,
      "points" : [ {
        "x" : 932,
        "y" : 397
      } ],
      "stoichiometry" : 3
    }, {
      "id" : 34100,
      "points" : [ {
        "x" : 876,
        "y" : 343
      } ]
    } ],
    "outputs" : [ {
      "id" : 34192
    } ],
    "catalysts" : [ {
      "id" : 34100,
      "points" : [ {
        "x" : 876,
        "y" : 318
      } ]
    } ]
  }, {
    "id" : 34193,
    "reactomeId" : 10346414,
    "displayName" : "Degradation of multiubiquitinated Cdh1",
    "schemaClass" : "BlackBoxEvent",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 797,
      "y" : 264
    },
    "minX" : 747,
    "maxX" : 861,
    "minY" : 257,
    "maxY" : 275,
    "reactionType" : "omitted",
    "segments" : [ {
      "from" : {
        "x" : 861,
        "y" : 257
      },
      "to" : {
        "x" : 797,
        "y" : 264
      }
    }, {
      "from" : {
        "x" : 797,
        "y" : 264
      },
      "to" : {
        "x" : 747,
        "y" : 275
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 791,
        "y" : 258
      },
      "b" : {
        "x" : 803,
        "y" : 270
      },
      "s" : "\\\\",
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 797,
        "y" : 264
      }
    },
    "inputs" : [ {
      "id" : 34192
    } ],
    "outputs" : [ {
      "id" : 34101,
      "points" : [ {
        "x" : 399,
        "y" : 303
      } ]
    }, {
      "id" : 34194,
      "points" : [ {
        "x" : 716,
        "y" : 233
      } ],
      "stoichiometry" : 3
    } ],
    "catalysts" : [ {
      "id" : 34195,
      "points" : [ {
        "x" : 791,
        "y" : 199
      } ]
    } ]
  }, {
    "id" : 34129,
    "reactomeId" : 10342882,
    "displayName" : "Inactivation of APC/C via CDC20 sequestration",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 400,
      "y" : 1430
    },
    "minX" : 376,
    "maxX" : 433,
    "minY" : 1424,
    "maxY" : 1436,
    "reactionType" : "binding",
    "segments" : [ {
      "from" : {
        "x" : 433,
        "y" : 1429
      },
      "to" : {
        "x" : 400,
        "y" : 1430
      }
    }, {
      "from" : {
        "x" : 400,
        "y" : 1430
      },
      "to" : {
        "x" : 376,
        "y" : 1431
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 383,
        "y" : 1427
      },
      "b" : {
        "x" : 376,
        "y" : 1431
      },
      "c" : {
        "x" : 383,
        "y" : 1435
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 383,
        "y" : 1435
      }
    },
    "reactionShape" : {
      "c" : {
        "x" : 400,
        "y" : 1430
      },
      "r" : 5,
      "type" : "CIRCLE",
      "centre" : {
        "x" : 400,
        "y" : 1430
      }
    },
    "inputs" : [ {
      "id" : 34130,
      "points" : [ {
        "x" : 480,
        "y" : 1405
      } ]
    }, {
      "id" : 34131,
      "points" : [ {
        "x" : 440,
        "y" : 1447
      } ]
    } ],
    "outputs" : [ {
      "id" : 34132
    } ]
  }, {
    "id" : 34196,
    "reactomeId" : 10346582,
    "displayName" : "Activation of APC/C:Cdc20 by dissociation of Cdc20:phospho-APC/C from Cdc20:phospho-APC/C:Mad2:Bub3:BubR1",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 1115,
      "y" : 1299
    },
    "minX" : 858,
    "maxX" : 1161,
    "minY" : 1293,
    "maxY" : 1305,
    "reactionType" : "dissociation",
    "segments" : [ {
      "from" : {
        "x" : 858,
        "y" : 1299
      },
      "to" : {
        "x" : 1115,
        "y" : 1299
      }
    }, {
      "from" : {
        "x" : 1115,
        "y" : 1299
      },
      "to" : {
        "x" : 1161,
        "y" : 1300
      }
    } ],
    "reactionShape" : {
      "c" : {
        "x" : 1115,
        "y" : 1299
      },
      "r" : 5,
      "r1" : 3,
      "type" : "DOUBLE_CIRCLE",
      "empty" : true,
      "centre" : {
        "x" : 1115,
        "y" : 1299
      }
    },
    "inputs" : [ {
      "id" : 34139
    } ],
    "outputs" : [ {
      "id" : 34197,
      "points" : [ {
        "x" : 1205,
        "y" : 1341
      } ]
    }, {
      "id" : 34160,
      "points" : [ {
        "x" : 1157,
        "y" : 1021
      }, {
        "x" : 1160,
        "y" : 1265
      } ]
    } ]
  }, {
    "id" : 34133,
    "reactomeId" : 10342886,
    "displayName" : "Formation of the MCC complex",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 539,
      "y" : 1505
    },
    "minX" : 501,
    "maxX" : 622,
    "minY" : 1427,
    "maxY" : 1511,
    "reactionType" : "binding",
    "segments" : [ {
      "from" : {
        "x" : 501,
        "y" : 1507
      },
      "to" : {
        "x" : 539,
        "y" : 1505
      }
    }, {
      "from" : {
        "x" : 539,
        "y" : 1505
      },
      "to" : {
        "x" : 622,
        "y" : 1427
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 620,
        "y" : 1435
      },
      "b" : {
        "x" : 622,
        "y" : 1427
      },
      "c" : {
        "x" : 614,
        "y" : 1429
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 614,
        "y" : 1429
      }
    },
    "reactionShape" : {
      "c" : {
        "x" : 539,
        "y" : 1505
      },
      "r" : 5,
      "type" : "CIRCLE",
      "centre" : {
        "x" : 539,
        "y" : 1505
      }
    },
    "inputs" : [ {
      "id" : 34130,
      "points" : [ {
        "x" : 500,
        "y" : 1405
      } ]
    }, {
      "id" : 34131,
      "points" : [ {
        "x" : 472,
        "y" : 1490
      } ]
    }, {
      "id" : 34134,
      "points" : [ {
        "x" : 442,
        "y" : 1545
      } ]
    }, {
      "id" : 34135,
      "points" : [ {
        "x" : 529,
        "y" : 1549
      } ]
    } ],
    "outputs" : [ {
      "id" : 34136
    } ]
  }, {
    "id" : 34198,
    "reactomeId" : 10348234,
    "displayName" : "APC/C:Cdh1-mediated degradation of Skp2",
    "schemaClass" : "BlackBoxEvent",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 950,
      "y" : 173
    },
    "minX" : 303,
    "maxX" : 1040,
    "minY" : 91,
    "maxY" : 220,
    "reactionType" : "omitted",
    "segments" : [ {
      "from" : {
        "x" : 1040,
        "y" : 220
      },
      "to" : {
        "x" : 950,
        "y" : 173
      }
    }, {
      "from" : {
        "x" : 950,
        "y" : 173
      },
      "to" : {
        "x" : 303,
        "y" : 91
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 944,
        "y" : 167
      },
      "b" : {
        "x" : 956,
        "y" : 179
      },
      "s" : "\\\\",
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 950,
        "y" : 173
      }
    },
    "inputs" : [ {
      "id" : 34199
    } ],
    "outputs" : [ {
      "id" : 34093,
      "points" : [ {
        "x" : 234,
        "y" : 144
      } ]
    }, {
      "id" : 34200,
      "points" : [ {
        "x" : 940,
        "y" : 124
      } ]
    }, {
      "id" : 34194,
      "points" : [ {
        "x" : 698,
        "y" : 199
      }, {
        "x" : 643,
        "y" : 152
      } ],
      "stoichiometry" : 3
    } ],
    "catalysts" : [ {
      "id" : 34195,
      "points" : [ {
        "x" : 851,
        "y" : 193
      }, {
        "x" : 940,
        "y" : 208
      } ]
    } ]
  }, {
    "id" : 34137,
    "reactomeId" : 10342878,
    "displayName" : "Binding of the MCC complex to the APC/C complex",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 666,
      "y" : 1302
    },
    "minX" : 627,
    "maxX" : 705,
    "minY" : 1296,
    "maxY" : 1308,
    "reactionType" : "binding",
    "segments" : [ {
      "from" : {
        "x" : 627,
        "y" : 1303
      },
      "to" : {
        "x" : 666,
        "y" : 1302
      }
    }, {
      "from" : {
        "x" : 666,
        "y" : 1302
      },
      "to" : {
        "x" : 705,
        "y" : 1301
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 698,
        "y" : 1305
      },
      "b" : {
        "x" : 705,
        "y" : 1301
      },
      "c" : {
        "x" : 698,
        "y" : 1297
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 698,
        "y" : 1297
      }
    },
    "reactionShape" : {
      "c" : {
        "x" : 666,
        "y" : 1302
      },
      "r" : 5,
      "type" : "CIRCLE",
      "centre" : {
        "x" : 666,
        "y" : 1302
      }
    },
    "inputs" : [ {
      "id" : 34136,
      "points" : [ {
        "x" : 642,
        "y" : 1371
      } ]
    }, {
      "id" : 34138,
      "points" : [ {
        "x" : 609,
        "y" : 1304
      } ]
    } ],
    "outputs" : [ {
      "id" : 34139
    } ]
  }, {
    "id" : 34201,
    "reactomeId" : 10434085,
    "displayName" : "RB1 recruits APC/C:Cdh1 complex to SKP2",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 1216,
      "y" : 148
    },
    "minX" : 1197,
    "maxX" : 1222,
    "minY" : 92,
    "maxY" : 198,
    "reactionType" : "binding",
    "segments" : [ {
      "from" : {
        "x" : 1197,
        "y" : 92
      },
      "to" : {
        "x" : 1216,
        "y" : 148
      }
    }, {
      "from" : {
        "x" : 1216,
        "y" : 148
      },
      "to" : {
        "x" : 1219,
        "y" : 198
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 1215,
        "y" : 191
      },
      "b" : {
        "x" : 1219,
        "y" : 198
      },
      "c" : {
        "x" : 1223,
        "y" : 191
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 1223,
        "y" : 191
      }
    },
    "reactionShape" : {
      "c" : {
        "x" : 1216,
        "y" : 148
      },
      "r" : 5,
      "type" : "CIRCLE",
      "centre" : {
        "x" : 1216,
        "y" : 148
      }
    },
    "inputs" : [ {
      "id" : 34093,
      "points" : [ {
        "x" : 231,
        "y" : 144
      }, {
        "x" : 298,
        "y" : 84
      } ]
    }, {
      "id" : 34200,
      "points" : [ {
        "x" : 1024,
        "y" : 120
      } ]
    }, {
      "id" : 34202,
      "points" : [ {
        "x" : 1243,
        "y" : 94
      } ]
    } ],
    "outputs" : [ {
      "id" : 34203
    } ]
  }, {
    "id" : 34140,
    "reactomeId" : 10346474,
    "displayName" : "Free APC/C phosphorylated by Plk1",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 215,
      "y" : 329
    },
    "minX" : 185,
    "maxX" : 289,
    "minY" : 316,
    "maxY" : 335,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 185,
        "y" : 322
      },
      "to" : {
        "x" : 215,
        "y" : 329
      }
    }, {
      "from" : {
        "x" : 215,
        "y" : 329
      },
      "to" : {
        "x" : 289,
        "y" : 316
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 283,
        "y" : 321
      },
      "b" : {
        "x" : 289,
        "y" : 316
      },
      "c" : {
        "x" : 281,
        "y" : 313
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 281,
        "y" : 313
      }
    },
    "reactionShape" : {
      "a" : {
        "x" : 209,
        "y" : 323
      },
      "b" : {
        "x" : 221,
        "y" : 335
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 215,
        "y" : 329
      }
    },
    "outputs" : [ {
      "id" : 34101
    } ],
    "catalysts" : [ {
      "id" : 34120,
      "points" : [ {
        "x" : 199,
        "y" : 427
      } ]
    } ]
  }, {
    "id" : 34204,
    "reactomeId" : 10434083,
    "displayName" : "APC/C:Cdh1 polyubiquitinates SKP2",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 1223,
      "y" : 319
    },
    "minX" : 1139,
    "maxX" : 1275,
    "minY" : 279,
    "maxY" : 341,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 1275,
        "y" : 341
      },
      "to" : {
        "x" : 1223,
        "y" : 319
      }
    }, {
      "from" : {
        "x" : 1223,
        "y" : 319
      },
      "to" : {
        "x" : 1139,
        "y" : 279
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 1147,
        "y" : 278
      },
      "b" : {
        "x" : 1139,
        "y" : 279
      },
      "c" : {
        "x" : 1144,
        "y" : 286
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 1144,
        "y" : 286
      }
    },
    "reactionShape" : {
      "a" : {
        "x" : 1217,
        "y" : 313
      },
      "b" : {
        "x" : 1229,
        "y" : 325
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 1223,
        "y" : 319
      }
    },
    "inputs" : [ {
      "id" : 34191,
      "points" : [ {
        "x" : 972,
        "y" : 407
      } ],
      "stoichiometry" : 3
    }, {
      "id" : 34203,
      "points" : [ {
        "x" : 1268,
        "y" : 225
      }, {
        "x" : 1289,
        "y" : 229
      } ]
    } ],
    "outputs" : [ {
      "id" : 34199
    } ],
    "catalysts" : [ {
      "id" : 34203,
      "points" : [ {
        "x" : 1221,
        "y" : 239
      } ]
    } ]
  }, {
    "id" : 34141,
    "reactomeId" : 10346511,
    "displayName" : "Free APC/C phosphorylated by Cyclin B:Cdc2",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 243,
      "y" : 304
    },
    "minX" : 185,
    "maxX" : 289,
    "minY" : 298,
    "maxY" : 310,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 185,
        "y" : 306
      },
      "to" : {
        "x" : 243,
        "y" : 304
      }
    }, {
      "from" : {
        "x" : 243,
        "y" : 304
      },
      "to" : {
        "x" : 289,
        "y" : 305
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 282,
        "y" : 309
      },
      "b" : {
        "x" : 289,
        "y" : 305
      },
      "c" : {
        "x" : 282,
        "y" : 301
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 282,
        "y" : 301
      }
    },
    "reactionShape" : {
      "a" : {
        "x" : 237,
        "y" : 298
      },
      "b" : {
        "x" : 249,
        "y" : 310
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 243,
        "y" : 304
      }
    },
    "outputs" : [ {
      "id" : 34101
    } ],
    "catalysts" : [ {
      "id" : 34115,
      "points" : [ {
        "x" : 320,
        "y" : 400
      } ]
    } ]
  }, {
    "id" : 34142,
    "reactomeId" : 10346558,
    "displayName" : "Association of Cyclin A with the APC/C",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 955,
      "y" : 1355
    },
    "minX" : 917,
    "maxX" : 988,
    "minY" : 1349,
    "maxY" : 1361,
    "reactionType" : "binding",
    "segments" : [ {
      "from" : {
        "x" : 917,
        "y" : 1356
      },
      "to" : {
        "x" : 955,
        "y" : 1355
      }
    }, {
      "from" : {
        "x" : 955,
        "y" : 1355
      },
      "to" : {
        "x" : 988,
        "y" : 1354
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 981,
        "y" : 1358
      },
      "b" : {
        "x" : 988,
        "y" : 1354
      },
      "c" : {
        "x" : 981,
        "y" : 1350
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 981,
        "y" : 1350
      }
    },
    "reactionShape" : {
      "c" : {
        "x" : 955,
        "y" : 1355
      },
      "r" : 5,
      "type" : "CIRCLE",
      "centre" : {
        "x" : 955,
        "y" : 1355
      }
    },
    "inputs" : [ {
      "id" : 34143,
      "points" : [ {
        "x" : 1008,
        "y" : 1396
      } ]
    }, {
      "id" : 34139,
      "points" : [ {
        "x" : 811,
        "y" : 1316
      } ]
    } ],
    "outputs" : [ {
      "id" : 34144
    } ]
  }, {
    "id" : 34145,
    "reactomeId" : 10346456,
    "displayName" : "Ubiquitination of Cyclin A by APC/C:Cdc20 complex",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 806,
      "y" : 1239
    },
    "minX" : 702,
    "maxX" : 837,
    "minY" : 1215,
    "maxY" : 1245,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 837,
        "y" : 1219
      },
      "to" : {
        "x" : 806,
        "y" : 1239
      }
    }, {
      "from" : {
        "x" : 806,
        "y" : 1239
      },
      "to" : {
        "x" : 702,
        "y" : 1215
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 710,
        "y" : 1213
      },
      "b" : {
        "x" : 702,
        "y" : 1215
      },
      "c" : {
        "x" : 708,
        "y" : 1220
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 708,
        "y" : 1220
      }
    },
    "reactionShape" : {
      "a" : {
        "x" : 800,
        "y" : 1233
      },
      "b" : {
        "x" : 812,
        "y" : 1245
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 806,
        "y" : 1239
      }
    },
    "inputs" : [ {
      "id" : 34144,
      "points" : [ {
        "x" : 1024,
        "y" : 1333
      } ]
    }, {
      "id" : 34146,
      "points" : [ {
        "x" : 876,
        "y" : 1210
      } ],
      "stoichiometry" : 4
    } ],
    "outputs" : [ {
      "id" : 34147
    } ],
    "catalysts" : [ {
      "id" : 34139,
      "points" : [ {
        "x" : 789,
        "y" : 1285
      }, {
        "x" : 804,
        "y" : 1267
      } ]
    } ]
  }, {
    "id" : 34148,
    "reactomeId" : 10346586,
    "displayName" : "Degradation multiubiquitinated Cyclin A",
    "schemaClass" : "BlackBoxEvent",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 737,
      "y" : 1193
    },
    "minX" : 702,
    "maxX" : 766,
    "minY" : 1187,
    "maxY" : 1199,
    "reactionType" : "omitted",
    "segments" : [ {
      "from" : {
        "x" : 702,
        "y" : 1193
      },
      "to" : {
        "x" : 737,
        "y" : 1193
      }
    }, {
      "from" : {
        "x" : 737,
        "y" : 1193
      },
      "to" : {
        "x" : 766,
        "y" : 1192
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 731,
        "y" : 1187
      },
      "b" : {
        "x" : 743,
        "y" : 1199
      },
      "s" : "\\\\",
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 737,
        "y" : 1193
      }
    },
    "inputs" : [ {
      "id" : 34147
    } ],
    "outputs" : [ {
      "id" : 34149,
      "points" : [ {
        "x" : 802,
        "y" : 1140
      } ]
    }, {
      "id" : 34139,
      "points" : [ {
        "x" : 779,
        "y" : 1285
      } ]
    }, {
      "id" : 34146,
      "points" : [ {
        "x" : 863,
        "y" : 1192
      } ],
      "stoichiometry" : 4
    } ],
    "catalysts" : [ {
      "id" : 34150,
      "points" : [ {
        "x" : 397,
        "y" : 1075
      }, {
        "x" : 736,
        "y" : 1161
      } ]
    } ]
  }, {
    "id" : 34151,
    "reactomeId" : 10347654,
    "displayName" : "Association of Nek2A with MCC:APC/C",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 746,
      "y" : 1396
    },
    "minX" : 740,
    "maxX" : 752,
    "minY" : 1341,
    "maxY" : 1472,
    "reactionType" : "binding",
    "segments" : [ {
      "from" : {
        "x" : 745,
        "y" : 1341
      },
      "to" : {
        "x" : 746,
        "y" : 1396
      }
    }, {
      "from" : {
        "x" : 746,
        "y" : 1396
      },
      "to" : {
        "x" : 745,
        "y" : 1472
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 741,
        "y" : 1465
      },
      "b" : {
        "x" : 745,
        "y" : 1472
      },
      "c" : {
        "x" : 749,
        "y" : 1465
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 749,
        "y" : 1465
      }
    },
    "reactionShape" : {
      "c" : {
        "x" : 746,
        "y" : 1396
      },
      "r" : 5,
      "type" : "CIRCLE",
      "centre" : {
        "x" : 746,
        "y" : 1396
      }
    },
    "inputs" : [ {
      "id" : 34139,
      "points" : [ {
        "x" : 770,
        "y" : 1316
      } ]
    }, {
      "id" : 34152,
      "points" : [ {
        "x" : 724,
        "y" : 1339
      } ]
    } ],
    "outputs" : [ {
      "id" : 34153
    } ]
  }, {
    "id" : 34154,
    "reactomeId" : 10347659,
    "displayName" : "Multiubiquitination of Nek2A",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 902,
      "y" : 1501
    },
    "minX" : 853,
    "maxX" : 947,
    "minY" : 1495,
    "maxY" : 1507,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 853,
        "y" : 1502
      },
      "to" : {
        "x" : 902,
        "y" : 1501
      }
    }, {
      "from" : {
        "x" : 902,
        "y" : 1501
      },
      "to" : {
        "x" : 947,
        "y" : 1502
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 940,
        "y" : 1506
      },
      "b" : {
        "x" : 947,
        "y" : 1502
      },
      "c" : {
        "x" : 940,
        "y" : 1498
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 940,
        "y" : 1498
      }
    },
    "reactionShape" : {
      "a" : {
        "x" : 896,
        "y" : 1495
      },
      "b" : {
        "x" : 908,
        "y" : 1507
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 902,
        "y" : 1501
      }
    },
    "inputs" : [ {
      "id" : 34153,
      "points" : [ {
        "x" : 797,
        "y" : 1501
      } ]
    }, {
      "id" : 34155,
      "points" : [ {
        "x" : 831,
        "y" : 1447
      } ],
      "stoichiometry" : 3
    } ],
    "outputs" : [ {
      "id" : 34156
    } ],
    "catalysts" : [ {
      "id" : 34153,
      "points" : [ {
        "x" : 797,
        "y" : 1510
      }, {
        "x" : 902,
        "y" : 1533
      } ]
    } ]
  }, {
    "id" : 34091,
    "reactomeId" : 10348238,
    "displayName" : "Association of Cyclin A:Cdk2 with Cdh1",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 231,
      "y" : 219
    },
    "minX" : 210,
    "maxX" : 271,
    "minY" : 213,
    "maxY" : 225,
    "reactionType" : "binding",
    "segments" : [ {
      "from" : {
        "x" : 210,
        "y" : 218
      },
      "to" : {
        "x" : 231,
        "y" : 219
      }
    }, {
      "from" : {
        "x" : 231,
        "y" : 219
      },
      "to" : {
        "x" : 271,
        "y" : 218
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 264,
        "y" : 222
      },
      "b" : {
        "x" : 271,
        "y" : 218
      },
      "c" : {
        "x" : 264,
        "y" : 214
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 264,
        "y" : 214
      }
    },
    "reactionShape" : {
      "c" : {
        "x" : 231,
        "y" : 219
      },
      "r" : 5,
      "type" : "CIRCLE",
      "centre" : {
        "x" : 231,
        "y" : 219
      }
    },
    "inputs" : [ {
      "id" : 34092,
      "points" : [ {
        "x" : 180,
        "y" : 218
      } ]
    }, {
      "id" : 34093,
      "points" : [ {
        "x" : 211,
        "y" : 186
      } ]
    } ],
    "outputs" : [ {
      "id" : 34094
    } ]
  }, {
    "id" : 34157,
    "reactomeId" : 10347661,
    "displayName" : "Degradation of multiubiquitinated Nek2A",
    "schemaClass" : "BlackBoxEvent",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 931,
      "y" : 1424
    },
    "minX" : 897,
    "maxX" : 988,
    "minY" : 1396,
    "maxY" : 1484,
    "reactionType" : "omitted",
    "segments" : [ {
      "from" : {
        "x" : 988,
        "y" : 1484
      },
      "to" : {
        "x" : 931,
        "y" : 1424
      }
    }, {
      "from" : {
        "x" : 931,
        "y" : 1424
      },
      "to" : {
        "x" : 897,
        "y" : 1396
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 925,
        "y" : 1418
      },
      "b" : {
        "x" : 937,
        "y" : 1430
      },
      "s" : "\\\\",
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 931,
        "y" : 1424
      }
    },
    "inputs" : [ {
      "id" : 34156
    } ],
    "outputs" : [ {
      "id" : 34139,
      "points" : [ {
        "x" : 796,
        "y" : 1316
      } ]
    }, {
      "id" : 34155,
      "points" : [ {
        "x" : 850,
        "y" : 1413
      } ],
      "stoichiometry" : 3
    } ]
  }, {
    "id" : 34158,
    "reactomeId" : 10346480,
    "displayName" : "Association of Cyclin B:Cdc2 with Cdc20:APC/C complex",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 1294,
      "y" : 1142
    },
    "minX" : 1280,
    "maxX" : 1300,
    "minY" : 1106,
    "maxY" : 1188,
    "reactionType" : "binding",
    "segments" : [ {
      "from" : {
        "x" : 1280,
        "y" : 1106
      },
      "to" : {
        "x" : 1294,
        "y" : 1142
      }
    }, {
      "from" : {
        "x" : 1294,
        "y" : 1142
      },
      "to" : {
        "x" : 1294,
        "y" : 1188
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 1290,
        "y" : 1181
      },
      "b" : {
        "x" : 1294,
        "y" : 1188
      },
      "c" : {
        "x" : 1298,
        "y" : 1181
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 1298,
        "y" : 1181
      }
    },
    "reactionShape" : {
      "c" : {
        "x" : 1294,
        "y" : 1142
      },
      "r" : 5,
      "type" : "CIRCLE",
      "centre" : {
        "x" : 1294,
        "y" : 1142
      }
    },
    "inputs" : [ {
      "id" : 34159,
      "points" : [ {
        "x" : 1312,
        "y" : 1068
      } ]
    }, {
      "id" : 34160,
      "points" : [ {
        "x" : 1177,
        "y" : 1021
      } ]
    } ],
    "outputs" : [ {
      "id" : 34161
    } ]
  }, {
    "id" : 34095,
    "reactomeId" : 10346427,
    "displayName" : "Phosphorylation of Cdh1 by Cyclin A:Cdk2",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 449,
      "y" : 203
    },
    "minX" : 423,
    "maxX" : 478,
    "minY" : 197,
    "maxY" : 209,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 423,
        "y" : 202
      },
      "to" : {
        "x" : 449,
        "y" : 203
      }
    }, {
      "from" : {
        "x" : 449,
        "y" : 203
      },
      "to" : {
        "x" : 478,
        "y" : 204
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 443,
        "y" : 197
      },
      "b" : {
        "x" : 455,
        "y" : 209
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 449,
        "y" : 203
      }
    },
    "inputs" : [ {
      "id" : 34094,
      "points" : [ {
        "x" : 400,
        "y" : 206
      } ]
    }, {
      "id" : 34096,
      "points" : [ {
        "x" : 390,
        "y" : 176
      } ]
    } ],
    "outputs" : [ {
      "id" : 34097,
      "points" : [ {
        "x" : 498,
        "y" : 172
      } ]
    }, {
      "id" : 34098,
      "points" : [ {
        "x" : 498,
        "y" : 207
      } ]
    } ],
    "catalysts" : [ {
      "id" : 34094,
      "points" : [ {
        "x" : 400,
        "y" : 226
      }, {
        "x" : 449,
        "y" : 233
      } ]
    } ]
  }, {
    "id" : 34162,
    "reactomeId" : 10346574,
    "displayName" : "Ubiquitination of Cyclin B by phospho-APC/C:Cdc20 complex",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 1145,
      "y" : 1216
    },
    "minX" : 1100,
    "maxX" : 1192,
    "minY" : 1210,
    "maxY" : 1222,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 1192,
        "y" : 1215
      },
      "to" : {
        "x" : 1145,
        "y" : 1216
      }
    }, {
      "from" : {
        "x" : 1145,
        "y" : 1216
      },
      "to" : {
        "x" : 1100,
        "y" : 1216
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 1107,
        "y" : 1212
      },
      "b" : {
        "x" : 1100,
        "y" : 1216
      },
      "c" : {
        "x" : 1107,
        "y" : 1220
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 1107,
        "y" : 1220
      }
    },
    "reactionShape" : {
      "a" : {
        "x" : 1139,
        "y" : 1210
      },
      "b" : {
        "x" : 1151,
        "y" : 1222
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 1145,
        "y" : 1216
      }
    },
    "inputs" : [ {
      "id" : 34161,
      "points" : [ {
        "x" : 1227,
        "y" : 1215
      } ]
    }, {
      "id" : 34163,
      "points" : [ {
        "x" : 1230,
        "y" : 1279
      } ],
      "stoichiometry" : 4
    } ],
    "outputs" : [ {
      "id" : 34164
    } ],
    "catalysts" : [ {
      "id" : 34161,
      "points" : [ {
        "x" : 1233,
        "y" : 1188
      }, {
        "x" : 1190,
        "y" : 1173
      } ]
    } ]
  }, {
    "id" : 34099,
    "reactomeId" : 10346513,
    "displayName" : "Dissociation of phospho-Cdh1 from the APC/C complex",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 719,
      "y" : 318
    },
    "minX" : 675,
    "maxX" : 764,
    "minY" : 312,
    "maxY" : 324,
    "reactionType" : "dissociation",
    "segments" : [ {
      "from" : {
        "x" : 764,
        "y" : 318
      },
      "to" : {
        "x" : 719,
        "y" : 318
      }
    }, {
      "from" : {
        "x" : 719,
        "y" : 318
      },
      "to" : {
        "x" : 675,
        "y" : 319
      }
    } ],
    "reactionShape" : {
      "c" : {
        "x" : 719,
        "y" : 318
      },
      "r" : 5,
      "r1" : 3,
      "type" : "DOUBLE_CIRCLE",
      "empty" : true,
      "centre" : {
        "x" : 719,
        "y" : 318
      }
    },
    "inputs" : [ {
      "id" : 34100
    } ],
    "outputs" : [ {
      "id" : 34101,
      "points" : [ {
        "x" : 399,
        "y" : 309
      } ]
    }, {
      "id" : 34102,
      "points" : [ {
        "x" : 649,
        "y" : 339
      } ]
    } ]
  }, {
    "id" : 34165,
    "reactomeId" : 10346525,
    "displayName" : "Degradation of multiubiquitinated Cyclin B",
    "schemaClass" : "BlackBoxEvent",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 1029,
      "y" : 1145
    },
    "minX" : 1023,
    "maxX" : 1035,
    "minY" : 1106,
    "maxY" : 1183,
    "reactionType" : "omitted",
    "segments" : [ {
      "from" : {
        "x" : 1030,
        "y" : 1183
      },
      "to" : {
        "x" : 1029,
        "y" : 1145
      }
    }, {
      "from" : {
        "x" : 1029,
        "y" : 1145
      },
      "to" : {
        "x" : 1027,
        "y" : 1106
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 1023,
        "y" : 1139
      },
      "b" : {
        "x" : 1035,
        "y" : 1151
      },
      "s" : "\\\\",
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 1029,
        "y" : 1145
      }
    },
    "inputs" : [ {
      "id" : 34164
    } ],
    "outputs" : [ {
      "id" : 34160,
      "points" : [ {
        "x" : 1134,
        "y" : 1021
      } ]
    }, {
      "id" : 34166,
      "points" : [ {
        "x" : 808,
        "y" : 1067
      } ],
      "stoichiometry" : 4
    }, {
      "id" : 34149,
      "points" : [ {
        "x" : 864,
        "y" : 1121
      } ]
    } ]
  }, {
    "id" : 34103,
    "reactomeId" : 10346447,
    "displayName" : "Association of Emi1 with Cdh1",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 808,
      "y" : 483
    },
    "minX" : 744,
    "maxX" : 836,
    "minY" : 477,
    "maxY" : 489,
    "reactionType" : "binding",
    "segments" : [ {
      "from" : {
        "x" : 744,
        "y" : 483
      },
      "to" : {
        "x" : 808,
        "y" : 483
      }
    }, {
      "from" : {
        "x" : 808,
        "y" : 483
      },
      "to" : {
        "x" : 836,
        "y" : 483
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 829,
        "y" : 487
      },
      "b" : {
        "x" : 836,
        "y" : 483
      },
      "c" : {
        "x" : 829,
        "y" : 479
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 829,
        "y" : 479
      }
    },
    "reactionShape" : {
      "c" : {
        "x" : 808,
        "y" : 483
      },
      "r" : 5,
      "type" : "CIRCLE",
      "centre" : {
        "x" : 808,
        "y" : 483
      }
    },
    "inputs" : [ {
      "id" : 34104,
      "points" : [ {
        "x" : 716,
        "y" : 483
      } ]
    }, {
      "id" : 34105,
      "points" : [ {
        "x" : 729,
        "y" : 511
      } ]
    } ],
    "outputs" : [ {
      "id" : 34106
    } ]
  }, {
    "id" : 34167,
    "reactomeId" : 10346484,
    "displayName" : "Association of Securin with Cdc20:APC/C complex",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 1182,
      "y" : 934
    },
    "minX" : 1176,
    "maxX" : 1188,
    "minY" : 887,
    "maxY" : 955,
    "reactionType" : "binding",
    "segments" : [ {
      "from" : {
        "x" : 1183,
        "y" : 955
      },
      "to" : {
        "x" : 1182,
        "y" : 934
      }
    }, {
      "from" : {
        "x" : 1182,
        "y" : 934
      },
      "to" : {
        "x" : 1181,
        "y" : 887
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 1185,
        "y" : 894
      },
      "b" : {
        "x" : 1181,
        "y" : 887
      },
      "c" : {
        "x" : 1177,
        "y" : 894
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 1177,
        "y" : 894
      }
    },
    "reactionShape" : {
      "c" : {
        "x" : 1182,
        "y" : 934
      },
      "r" : 5,
      "type" : "CIRCLE",
      "centre" : {
        "x" : 1182,
        "y" : 934
      }
    },
    "inputs" : [ {
      "id" : 34168,
      "points" : [ {
        "x" : 1233,
        "y" : 964
      } ]
    }, {
      "id" : 34160,
      "points" : [ {
        "x" : 1167,
        "y" : 979
      } ]
    } ],
    "outputs" : [ {
      "id" : 34169
    } ]
  }, {
    "id" : 34170,
    "reactomeId" : 10346521,
    "displayName" : "Ubiquitination of Securin by phospho-APC/C:Cdc20 complex",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 890,
      "y" : 863
    },
    "minX" : 802,
    "maxX" : 929,
    "minY" : 842,
    "maxY" : 869,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 929,
        "y" : 842
      },
      "to" : {
        "x" : 890,
        "y" : 863
      }
    }, {
      "from" : {
        "x" : 890,
        "y" : 863
      },
      "to" : {
        "x" : 802,
        "y" : 863
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 809,
        "y" : 859
      },
      "b" : {
        "x" : 802,
        "y" : 863
      },
      "c" : {
        "x" : 809,
        "y" : 867
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 809,
        "y" : 867
      }
    },
    "reactionShape" : {
      "a" : {
        "x" : 884,
        "y" : 857
      },
      "b" : {
        "x" : 896,
        "y" : 869
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 890,
        "y" : 863
      }
    },
    "inputs" : [ {
      "id" : 34122,
      "points" : [ {
        "x" : 707,
        "y" : 778
      } ],
      "stoichiometry" : 3
    }, {
      "id" : 34169,
      "points" : [ {
        "x" : 1124,
        "y" : 855
      } ]
    } ],
    "outputs" : [ {
      "id" : 34171
    } ],
    "catalysts" : [ {
      "id" : 34169,
      "points" : [ {
        "x" : 1124,
        "y" : 870
      }, {
        "x" : 947,
        "y" : 908
      } ]
    } ]
  }, {
    "id" : 34107,
    "reactomeId" : 10346578,
    "displayName" : "Association of Emi1 with Cdc20",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 817,
      "y" : 604
    },
    "minX" : 811,
    "maxX" : 823,
    "minY" : 576,
    "maxY" : 637,
    "reactionType" : "binding",
    "segments" : [ {
      "from" : {
        "x" : 817,
        "y" : 576
      },
      "to" : {
        "x" : 817,
        "y" : 604
      }
    }, {
      "from" : {
        "x" : 817,
        "y" : 604
      },
      "to" : {
        "x" : 817,
        "y" : 637
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 813,
        "y" : 630
      },
      "b" : {
        "x" : 817,
        "y" : 637
      },
      "c" : {
        "x" : 821,
        "y" : 630
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 821,
        "y" : 630
      }
    },
    "reactionShape" : {
      "c" : {
        "x" : 817,
        "y" : 604
      },
      "r" : 5,
      "type" : "CIRCLE",
      "centre" : {
        "x" : 817,
        "y" : 604
      }
    },
    "inputs" : [ {
      "id" : 34108,
      "points" : [ {
        "x" : 861,
        "y" : 541
      } ]
    }, {
      "id" : 34105,
      "points" : [ {
        "x" : 744,
        "y" : 539
      } ]
    } ],
    "outputs" : [ {
      "id" : 34109
    } ]
  }, {
    "id" : 34172,
    "reactomeId" : 10346569,
    "displayName" : "Degradation of multiubiquitinated Securin",
    "schemaClass" : "BlackBoxEvent",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 760,
      "y" : 969
    },
    "minX" : 754,
    "maxX" : 766,
    "minY" : 899,
    "maxY" : 997,
    "reactionType" : "omitted",
    "segments" : [ {
      "from" : {
        "x" : 759,
        "y" : 899
      },
      "to" : {
        "x" : 760,
        "y" : 969
      }
    }, {
      "from" : {
        "x" : 760,
        "y" : 969
      },
      "to" : {
        "x" : 760,
        "y" : 997
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 754,
        "y" : 963
      },
      "b" : {
        "x" : 766,
        "y" : 975
      },
      "s" : "\\\\",
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 760,
        "y" : 969
      }
    },
    "inputs" : [ {
      "id" : 34171
    } ],
    "outputs" : [ {
      "id" : 34160,
      "points" : [ {
        "x" : 1103,
        "y" : 999
      } ]
    }, {
      "id" : 34166,
      "points" : [ {
        "x" : 760,
        "y" : 1043
      } ],
      "stoichiometry" : 4
    } ],
    "catalysts" : [ {
      "id" : 34150,
      "points" : [ {
        "x" : 404,
        "y" : 1047
      } ]
    } ]
  }, {
    "id" : 34173,
    "reactomeId" : 10346509,
    "displayName" : "Dephosphorylation of phospho-Cdh1",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 84,
      "y" : 1536
    },
    "minX" : 78,
    "maxX" : 90,
    "minY" : 1498,
    "maxY" : 1565,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 83,
        "y" : 1565
      },
      "to" : {
        "x" : 84,
        "y" : 1536
      }
    }, {
      "from" : {
        "x" : 84,
        "y" : 1536
      },
      "to" : {
        "x" : 84,
        "y" : 1498
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 78,
        "y" : 1530
      },
      "b" : {
        "x" : 90,
        "y" : 1542
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 84,
        "y" : 1536
      }
    },
    "inputs" : [ {
      "id" : 34174,
      "points" : [ {
        "x" : 116,
        "y" : 1592
      } ]
    }, {
      "id" : 34175,
      "points" : [ {
        "x" : 64,
        "y" : 1594
      } ]
    } ],
    "outputs" : [ {
      "id" : 34176,
      "points" : [ {
        "x" : 68,
        "y" : 1482
      } ]
    }, {
      "id" : 34177,
      "points" : [ {
        "x" : 137,
        "y" : 1475
      } ]
    } ],
    "catalysts" : [ {
      "id" : 34178,
      "points" : [ {
        "x" : 111,
        "y" : 1536
      } ]
    } ]
  }, {
    "id" : 34110,
    "reactomeId" : 10346498,
    "displayName" : "Phosphorylation of the Emi1 DSGxxS degron by Cyclin B:Cdc2",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 329,
      "y" : 528
    },
    "minX" : 301,
    "maxX" : 357,
    "minY" : 522,
    "maxY" : 534,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 301,
        "y" : 528
      },
      "to" : {
        "x" : 329,
        "y" : 528
      }
    }, {
      "from" : {
        "x" : 329,
        "y" : 528
      },
      "to" : {
        "x" : 357,
        "y" : 528
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 323,
        "y" : 522
      },
      "b" : {
        "x" : 335,
        "y" : 534
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 329,
        "y" : 528
      }
    },
    "inputs" : [ {
      "id" : 34111,
      "points" : [ {
        "x" : 254,
        "y" : 511
      } ]
    }, {
      "id" : 34112,
      "points" : [ {
        "x" : 264,
        "y" : 550
      } ]
    } ],
    "outputs" : [ {
      "id" : 34113,
      "points" : [ {
        "x" : 422,
        "y" : 532
      } ]
    }, {
      "id" : 34114,
      "points" : [ {
        "x" : 418,
        "y" : 483
      } ]
    } ],
    "catalysts" : [ {
      "id" : 34115,
      "points" : [ {
        "x" : 332,
        "y" : 439
      } ]
    } ]
  } ],
  "compartments" : [ {
    "id" : 34205,
    "reactomeId" : 7660,
    "displayName" : "nucleoplasm",
    "schemaClass" : "Compartment",
    "renderableClass" : "Compartment",
    "position" : {
      "x" : 763,
      "y" : 377
    },
    "minX" : 30,
    "maxX" : 1497,
    "minY" : 44,
    "maxY" : 711,
    "prop" : {
      "x" : 30,
      "y" : 44,
      "width" : 1467,
      "height" : 667
    },
    "textPosition" : {
      "x" : 1330,
      "y" : 661
    },
    "insets" : {
      "x" : 40,
      "y" : 54,
      "width" : 1447,
      "height" : 647
    },
    "bgColor" : {
      "r" : 250,
      "g" : 240,
      "b" : 240
    },
    "componentIds" : [ 34091, 34092, 34093, 34094, 34095, 34096, 34097, 34098, 34099, 34100, 34101, 34102, 34103, 34104, 34105, 34106, 34107, 34109, 34108, 34110, 34111, 34112, 34113, 34114, 34115, 34116, 34117, 34119, 34125, 34126, 34127, 34128, 34140, 34141, 34190, 34191, 34192, 34193, 34195, 34194, 34118, 34213, 34212, 34120, 34199, 34203, 34201, 34204, 34202, 34200, 34198 ]
  }, {
    "id" : 34206,
    "reactomeId" : 70101,
    "displayName" : "cytosol",
    "schemaClass" : "Compartment",
    "renderableClass" : "Compartment",
    "position" : {
      "x" : 770,
      "y" : 831
    },
    "minX" : 0,
    "maxX" : 1541,
    "minY" : 0,
    "maxY" : 1663,
    "prop" : {
      "x" : 0,
      "y" : 0,
      "width" : 1541,
      "height" : 1663
    },
    "textPosition" : {
      "x" : 1416,
      "y" : 1605
    },
    "insets" : {
      "x" : 10,
      "y" : 10,
      "width" : 1521,
      "height" : 1643
    },
    "bgColor" : {
      "r" : 250,
      "g" : 240,
      "b" : 240
    },
    "componentIds" : [ 34205, 34129, 34131, 34132, 34133, 34134, 34135, 34136, 34130, 34137, 34138, 34139, 34142, 34143, 34144, 34151, 34152, 34153, 34154, 34156, 34157, 34163, 34173, 34174, 34175, 34176, 34177, 34178, 34180, 34181, 34182, 34183, 34184, 34185, 34187, 34186, 34189, 34123, 34121, 34122, 34124, 34209, 34150, 34145, 34147, 34148, 34149, 34146, 34158, 34159, 34160, 34161, 34162, 34164, 34165, 34166, 34167, 34168, 34169, 34179, 34188, 34170, 34172, 34155, 34197, 34196, 34215, 34216, 34217, 34214, 34171, 34218 ]
  } ],
  "notes" : [ ],
  "links" : [ {
    "id" : 34212,
    "renderableClass" : "EntitySetAndMemberLink",
    "position" : {
      "x" : 658,
      "y" : 416
    },
    "minX" : 640,
    "maxX" : 676,
    "minY" : 367,
    "maxY" : 466,
    "segments" : [ {
      "from" : {
        "x" : 640,
        "y" : 367
      },
      "to" : {
        "x" : 676,
        "y" : 466
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 652,
        "y" : 410
      },
      "b" : {
        "x" : 664,
        "y" : 422
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 658,
        "y" : 416
      }
    },
    "inputs" : [ {
      "id" : 34102
    } ],
    "outputs" : [ {
      "id" : 34104
    } ]
  }, {
    "id" : 34213,
    "renderableClass" : "EntitySetAndMemberLink",
    "position" : {
      "x" : 629,
      "y" : 472
    },
    "minX" : 614,
    "maxX" : 644,
    "minY" : 466,
    "maxY" : 478,
    "segments" : [ {
      "from" : {
        "x" : 614,
        "y" : 468
      },
      "to" : {
        "x" : 644,
        "y" : 476
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 623,
        "y" : 466
      },
      "b" : {
        "x" : 635,
        "y" : 478
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 629,
        "y" : 472
      }
    },
    "inputs" : [ {
      "id" : 34126
    } ],
    "outputs" : [ {
      "id" : 34104
    } ]
  }, {
    "id" : 34214,
    "renderableClass" : "EntitySetAndMemberLink",
    "position" : {
      "x" : 362,
      "y" : 1373
    },
    "minX" : 253,
    "maxX" : 472,
    "minY" : 1359,
    "maxY" : 1387,
    "segments" : [ {
      "from" : {
        "x" : 472,
        "y" : 1387
      },
      "to" : {
        "x" : 253,
        "y" : 1359
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 356,
        "y" : 1367
      },
      "b" : {
        "x" : 368,
        "y" : 1379
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 362,
        "y" : 1373
      }
    },
    "inputs" : [ {
      "id" : 34130
    } ],
    "outputs" : [ {
      "id" : 34183
    } ]
  }, {
    "id" : 34215,
    "renderableClass" : "EntitySetAndMemberLink",
    "position" : {
      "x" : 1344,
      "y" : 1612
    },
    "minX" : 200,
    "maxX" : 1479,
    "minY" : 970,
    "maxY" : 1619,
    "segments" : [ {
      "from" : {
        "x" : 1293,
        "y" : 970
      },
      "to" : {
        "x" : 1479,
        "y" : 970
      }
    }, {
      "from" : {
        "x" : 1479,
        "y" : 970
      },
      "to" : {
        "x" : 1344,
        "y" : 1612
      }
    }, {
      "from" : {
        "x" : 1344,
        "y" : 1612
      },
      "to" : {
        "x" : 284,
        "y" : 1619
      }
    }, {
      "from" : {
        "x" : 284,
        "y" : 1619
      },
      "to" : {
        "x" : 200,
        "y" : 1384
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 1338,
        "y" : 1606
      },
      "b" : {
        "x" : 1350,
        "y" : 1618
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 1344,
        "y" : 1612
      }
    },
    "inputs" : [ {
      "id" : 34168
    } ],
    "outputs" : [ {
      "id" : 34183
    } ]
  }, {
    "id" : 34216,
    "renderableClass" : "EntitySetAndMemberLink",
    "position" : {
      "x" : 449,
      "y" : 1372
    },
    "minX" : 426,
    "maxX" : 472,
    "minY" : 1363,
    "maxY" : 1381,
    "segments" : [ {
      "from" : {
        "x" : 472,
        "y" : 1381
      },
      "to" : {
        "x" : 426,
        "y" : 1363
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 443,
        "y" : 1366
      },
      "b" : {
        "x" : 455,
        "y" : 1378
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 449,
        "y" : 1372
      }
    },
    "inputs" : [ {
      "id" : 34130
    } ],
    "outputs" : [ {
      "id" : 34209
    } ]
  }, {
    "id" : 34217,
    "renderableClass" : "EntitySetAndMemberLink",
    "position" : {
      "x" : 288,
      "y" : 1409
    },
    "minX" : 187,
    "maxX" : 389,
    "minY" : 1363,
    "maxY" : 1456,
    "segments" : [ {
      "from" : {
        "x" : 187,
        "y" : 1456
      },
      "to" : {
        "x" : 389,
        "y" : 1363
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 282,
        "y" : 1403
      },
      "b" : {
        "x" : 294,
        "y" : 1415
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 288,
        "y" : 1409
      }
    },
    "inputs" : [ {
      "id" : 34177
    } ],
    "outputs" : [ {
      "id" : 34209
    } ]
  }, {
    "id" : 34218,
    "renderableClass" : "EntitySetAndEntitySetLink",
    "position" : {
      "x" : 304,
      "y" : 1349
    },
    "minX" : 253,
    "maxX" : 356,
    "minY" : 1343,
    "maxY" : 1355,
    "segments" : [ {
      "from" : {
        "x" : 253,
        "y" : 1351
      },
      "to" : {
        "x" : 356,
        "y" : 1348
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 298,
        "y" : 1343
      },
      "b" : {
        "x" : 310,
        "y" : 1355
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 304,
        "y" : 1349
      }
    },
    "inputs" : [ {
      "id" : 34183
    } ],
    "outputs" : [ {
      "id" : 34209
    } ]
  } ],
  "shadows" : [ {
    "id" : 34219,
    "reactomeId" : 10443478,
    "displayName" : "APC/C-mediated degradation of cell cycle proteins",
    "schemaClass" : "Pathway",
    "renderableClass" : "Shadow",
    "position" : {
      "x" : 733,
      "y" : 856
    },
    "minX" : 24,
    "maxX" : 1443,
    "minY" : 73,
    "maxY" : 1639,
    "prop" : {
      "x" : 24,
      "y" : 73,
      "width" : 1419,
      "height" : 1566
    },
    "points" : [ {
      "x" : 24,
      "y" : 73
    }, {
      "x" : 1443,
      "y" : 73
    }, {
      "x" : 1443,
      "y" : 1639
    }, {
      "x" : 24,
      "y" : 1639
    } ],
    "colour" : "#4684ee"
  } ],
  "minX" : 0,
  "maxX" : 1541,
  "minY" : 0,
  "maxY" : 1663,
  "disease" : false
}