{ "dbId" : 10443044, "stableId" : "R-BTA-2187338", "displayName" : "Visual phototransduction", "nodes" : [ { "id" : 27392, "reactomeId" : 70106, "displayName" : "H+", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 1493, "y" : 1020 }, "minX" : 1467, "maxX" : 1512, "minY" : 1004, "maxY" : 1052, "prop" : { "x" : 1475, "y" : 1005, "width" : 36, "height" : 30 }, "textPosition" : { "x" : 1479, "y" : 1009 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1506, "y" : 1010 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1506, "y" : 1010 } } }, "connectors" : [ { "edgeId" : 27390, "type" : "INPUT", "segments" : [ { "from" : { "x" : 1480, "y" : 1038 }, "to" : { "x" : 1467, "y" : 1052 } } ], "stoichiometry" : { "value" : 1 } } ], "trivial" : true }, { "id" : 27393, "reactomeId" : 29366, "displayName" : "NADP+", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 1332, "y" : 1088 }, "minX" : 1302, "maxX" : 1363, "minY" : 1052, "maxY" : 1103, "prop" : { "x" : 1302, "y" : 1073, "width" : 60, "height" : 30 }, "textPosition" : { "x" : 1306, "y" : 1077 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1357, "y" : 1078 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1357, "y" : 1078 } } }, "connectors" : [ { "edgeId" : 27390, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 1342, "y" : 1070 }, "to" : { "x" : 1358, "y" : 1052 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 1344, "y" : 1062 }, "b" : { "x" : 1342, "y" : 1070 }, "c" : { "x" : 1350, "y" : 1067 }, "type" : "ARROW", "centre" : { "x" : 1350, "y" : 1067 } } } ] }, { "id" : 27394, "reactomeId" : 10389377, "displayName" : "DHRS3", "schemaClass" : "EntityWithAccessionedSequence", "renderableClass" : "Protein", "position" : { "x" : 1429, "y" : 1000 }, "minX" : 1404, "maxX" : 1461, "minY" : 983, "maxY" : 1044, "prop" : { "x" : 1404, "y" : 989, "width" : 51, "height" : 22 }, "textPosition" : { "x" : 1404, "y" : 989 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1455, "y" : 989 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1455, "y" : 989 } } }, "connectors" : [ { "edgeId" : 27390, "type" : "CATALYST", "segments" : [ { "from" : { "x" : 1429, "y" : 1014 }, "to" : { "x" : 1429, "y" : 1036 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "c" : { "x" : 1429, "y" : 1040 }, "r" : 4, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1429, "y" : 1040 } } } ] }, { "id" : 27396, "reactomeId" : 10389678, "displayName" : "Gt-GTP", "schemaClass" : "Complex", "renderableClass" : "Complex", "position" : { "x" : 1614, "y" : 295 }, "minX" : 1588, "maxX" : 1647, "minY" : 278, "maxY" : 306, "prop" : { "x" : 1588, "y" : 284, "width" : 53, "height" : 22 }, "textPosition" : { "x" : 1589, "y" : 285 }, "bgColor" : { "r" : 204, "g" : 255, "b" : 255 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1641, "y" : 284 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1641, "y" : 284 } } }, "connectors" : [ { "edgeId" : 27395, "type" : "INPUT", "segments" : [ ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 27397, "reactomeId" : 10389676, "displayName" : "GNB1:GNGT1", "schemaClass" : "Complex", "renderableClass" : "Complex", "position" : { "x" : 1738, "y" : 292 }, "minX" : 1672, "maxX" : 1789, "minY" : 275, "maxY" : 313, "prop" : { "x" : 1694, "y" : 281, "width" : 89, "height" : 22 }, "textPosition" : { "x" : 1694, "y" : 282 }, "bgColor" : { "r" : 204, "g" : 255, "b" : 255 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1783, "y" : 281 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1783, "y" : 281 } } }, "connectors" : [ { "edgeId" : 27395, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 1717, "y" : 306 }, "to" : { "x" : 1699, "y" : 313 } }, { "from" : { "x" : 1699, "y" : 313 }, "to" : { "x" : 1672, "y" : 283 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 1712, "y" : 312 }, "b" : { "x" : 1717, "y" : 306 }, "c" : { "x" : 1709, "y" : 305 }, "type" : "ARROW", "centre" : { "x" : 1709, "y" : 305 } } } ] }, { "id" : 27398, "reactomeId" : 10337264, "displayName" : "GNAT1-GTP", "schemaClass" : "Complex", "renderableClass" : "Complex", "position" : { "x" : 1848, "y" : 291 }, "minX" : 1672, "maxX" : 1895, "minY" : 267, "maxY" : 302, "prop" : { "x" : 1807, "y" : 280, "width" : 82, "height" : 22 }, "textPosition" : { "x" : 1809, "y" : 281 }, "bgColor" : { "r" : 204, "g" : 255, "b" : 255 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1889, "y" : 280 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1889, "y" : 280 } } }, "connectors" : [ { "edgeId" : 27395, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 1804, "y" : 283 }, "to" : { "x" : 1723, "y" : 267 } }, { "from" : { "x" : 1723, "y" : 267 }, "to" : { "x" : 1672, "y" : 283 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 1796, "y" : 286 }, "b" : { "x" : 1804, "y" : 283 }, "c" : { "x" : 1798, "y" : 278 }, "type" : "ARROW", "centre" : { "x" : 1798, "y" : 278 } } } ] }, { "id" : 27400, "reactomeId" : 29356, "displayName" : "H2O", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 2271, "y" : 224 }, "minX" : 2222, "maxX" : 2300, "minY" : 186, "maxY" : 296, "prop" : { "x" : 2250, "y" : 209, "width" : 43, "height" : 30 }, "textPosition" : { "x" : 2254, "y" : 213 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 2288, "y" : 214 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 2288, "y" : 214 } } }, "connectors" : [ { "edgeId" : 27399, "type" : "INPUT", "segments" : [ { "from" : { "x" : 2282, "y" : 206 }, "to" : { "x" : 2300, "y" : 186 } } ], "stoichiometry" : { "value" : 1 } }, { "edgeId" : 27446, "type" : "INPUT", "segments" : [ { "from" : { "x" : 2260, "y" : 242 }, "to" : { "x" : 2222, "y" : 296 } } ], "stoichiometry" : { "value" : 1 } } ], "trivial" : true }, { "id" : 27401, "reactomeId" : 30991, "displayName" : "cGMP", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 2621, "y" : 186 }, "minX" : 2300, "maxX" : 2948, "minY" : 68, "maxY" : 247, "prop" : { "x" : 2597, "y" : 171, "width" : 49, "height" : 30 }, "textPosition" : { "x" : 2600, "y" : 175 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 2641, "y" : 176 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 2641, "y" : 176 } } }, "connectors" : [ { "edgeId" : 27462, "type" : "INPUT", "segments" : [ { "from" : { "x" : 2649, "y" : 179 }, "to" : { "x" : 2886, "y" : 115 } } ], "stoichiometry" : { "value" : 1 } }, { "edgeId" : 27399, "type" : "INPUT", "segments" : [ { "from" : { "x" : 2594, "y" : 186 }, "to" : { "x" : 2300, "y" : 186 } } ], "stoichiometry" : { "value" : 1 } }, { "edgeId" : 27404, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 2649, "y" : 177 }, "to" : { "x" : 2948, "y" : 68 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 2654, "y" : 171 }, "b" : { "x" : 2649, "y" : 177 }, "c" : { "x" : 2657, "y" : 178 }, "type" : "ARROW", "centre" : { "x" : 2657, "y" : 178 } } }, { "edgeId" : 27454, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 2631, "y" : 204 }, "to" : { "x" : 2663, "y" : 247 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 2638, "y" : 207 }, "b" : { "x" : 2631, "y" : 204 }, "c" : { "x" : 2632, "y" : 212 }, "type" : "ARROW", "centre" : { "x" : 2632, "y" : 212 } } } ] }, { "id" : 27402, "reactomeId" : 113578, "displayName" : "GMP", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 2056, "y" : 187 }, "minX" : 2001, "maxX" : 2112, "minY" : 164, "maxY" : 209, "prop" : { "x" : 2001, "y" : 165, "width" : 110, "height" : 44 }, "textPosition" : { "x" : 2038, "y" : 176 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 2106, "y" : 170 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 2106, "y" : 170 } } }, "connectors" : [ { "edgeId" : 27399, "type" : "OUTPUT", "segments" : [ ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 27403, "reactomeId" : 10337279, "displayName" : "GNAT1-GTP:PDE6", "schemaClass" : "Complex", "renderableClass" : "Complex", "position" : { "x" : 2118, "y" : 298 }, "minX" : 2060, "maxX" : 2262, "minY" : 194, "maxY" : 325, "prop" : { "x" : 2060, "y" : 287, "width" : 117, "height" : 22 }, "textPosition" : { "x" : 2061, "y" : 288 }, "bgColor" : { "r" : 204, "g" : 255, "b" : 255 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 2177, "y" : 287 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 2177, "y" : 287 } } }, "connectors" : [ { "edgeId" : 27399, "type" : "CATALYST", "segments" : [ { "from" : { "x" : 2117, "y" : 284 }, "to" : { "x" : 2117, "y" : 202 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "c" : { "x" : 2117, "y" : 198 }, "r" : 4, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 2117, "y" : 198 } } }, { "edgeId" : 27446, "type" : "INPUT", "segments" : [ { "from" : { "x" : 2180, "y" : 296 }, "to" : { "x" : 2222, "y" : 296 } } ], "stoichiometry" : { "value" : 1 } }, { "edgeId" : 27446, "type" : "CATALYST", "segments" : [ { "from" : { "x" : 2175, "y" : 312 }, "to" : { "x" : 2259, "y" : 325 } }, { "from" : { "x" : 2259, "y" : 325 }, "to" : { "x" : 2259, "y" : 312 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "c" : { "x" : 2258, "y" : 308 }, "r" : 4, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 2258, "y" : 308 } } } ] }, { "id" : 27405, "reactomeId" : 10337254, "displayName" : "cGMP:CNG channel", "schemaClass" : "Complex", "renderableClass" : "Complex", "position" : { "x" : 2836, "y" : 67 }, "minX" : 2753, "maxX" : 2906, "minY" : 50, "maxY" : 78, "prop" : { "x" : 2773, "y" : 56, "width" : 127, "height" : 22 }, "textPosition" : { "x" : 2773, "y" : 57 }, "bgColor" : { "r" : 204, "g" : 255, "b" : 255 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 2900, "y" : 56 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 2900, "y" : 56 } } }, "connectors" : [ { "edgeId" : 27462, "type" : "OUTPUT", "segments" : [ ], "stoichiometry" : { "value" : 1 } }, { "edgeId" : 27404, "type" : "INPUT", "segments" : [ ], "stoichiometry" : { "value" : 1 } }, { "edgeId" : 27407, "type" : "CATALYST", "segments" : [ { "from" : { "x" : 2770, "y" : 66 }, "to" : { "x" : 2761, "y" : 66 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "c" : { "x" : 2757, "y" : 66 }, "r" : 4, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 2757, "y" : 66 } } } ] }, { "id" : 27406, "reactomeId" : 10337252, "displayName" : "CNG channel", "schemaClass" : "Complex", "renderableClass" : "Complex", "position" : { "x" : 3030, "y" : 69 }, "minX" : 2886, "maxX" : 3081, "minY" : 52, "maxY" : 118, "prop" : { "x" : 2986, "y" : 58, "width" : 89, "height" : 22 }, "textPosition" : { "x" : 2986, "y" : 59 }, "bgColor" : { "r" : 204, "g" : 255, "b" : 255 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 3075, "y" : 58 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 3075, "y" : 58 } } }, "connectors" : [ { "edgeId" : 27462, "type" : "INPUT", "segments" : [ { "from" : { "x" : 2995, "y" : 83 }, "to" : { "x" : 2886, "y" : 115 } } ], "stoichiometry" : { "value" : 1 } }, { "edgeId" : 27463, "type" : "INPUT", "segments" : [ { "from" : { "x" : 3038, "y" : 83 }, "to" : { "x" : 3068, "y" : 118 } } ], "stoichiometry" : { "value" : 1 } }, { "edgeId" : 27404, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 2983, "y" : 68 }, "to" : { "x" : 2948, "y" : 68 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 2976, "y" : 72 }, "b" : { "x" : 2983, "y" : 68 }, "c" : { "x" : 2976, "y" : 64 }, "type" : "ARROW", "centre" : { "x" : 2976, "y" : 64 } } } ] }, { "id" : 27408, "reactomeId" : 74113, "displayName" : "Na+", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 2709, "y" : 16 }, "minX" : 2688, "maxX" : 2746, "minY" : 0, "maxY" : 66, "prop" : { "x" : 2688, "y" : 1, "width" : 43, "height" : 30 }, "textPosition" : { "x" : 2692, "y" : 5 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 2726, "y" : 6 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 2726, "y" : 6 } } }, "connectors" : [ { "edgeId" : 27407, "type" : "INPUT", "segments" : [ { "from" : { "x" : 2720, "y" : 34 }, "to" : { "x" : 2746, "y" : 66 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 27409, "reactomeId" : 74112, "displayName" : "Ca2+", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 2781, "y" : 16 }, "minX" : 2746, "maxX" : 2807, "minY" : 0, "maxY" : 66, "prop" : { "x" : 2756, "y" : 1, "width" : 50, "height" : 30 }, "textPosition" : { "x" : 2760, "y" : 5 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 2801, "y" : 6 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 2801, "y" : 6 } } }, "connectors" : [ { "edgeId" : 27407, "type" : "INPUT", "segments" : [ { "from" : { "x" : 2770, "y" : 34 }, "to" : { "x" : 2746, "y" : 66 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 27410, "reactomeId" : 83910, "displayName" : "Na+", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 2671, "y" : 102 }, "minX" : 2650, "maxX" : 2746, "minY" : 68, "maxY" : 117, "prop" : { "x" : 2650, "y" : 87, "width" : 43, "height" : 30 }, "textPosition" : { "x" : 2654, "y" : 91 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 2688, "y" : 92 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 2688, "y" : 92 } } }, "connectors" : [ { "edgeId" : 27407, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 2696, "y" : 92 }, "to" : { "x" : 2746, "y" : 68 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 2701, "y" : 85 }, "b" : { "x" : 2696, "y" : 92 }, "c" : { "x" : 2704, "y" : 93 }, "type" : "ARROW", "centre" : { "x" : 2704, "y" : 93 } } } ] }, { "id" : 27411, "reactomeId" : 74016, "displayName" : "Ca2+", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 2930, "y" : 179 }, "minX" : 2746, "maxX" : 3086, "minY" : 68, "maxY" : 243, "prop" : { "x" : 2905, "y" : 164, "width" : 50, "height" : 30 }, "textPosition" : { "x" : 2909, "y" : 168 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 2950, "y" : 169 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 2950, "y" : 169 } } }, "connectors" : [ { "edgeId" : 27463, "type" : "ACTIVATOR", "segments" : [ { "from" : { "x" : 2958, "y" : 173 }, "to" : { "x" : 3086, "y" : 147 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 3080, "y" : 152 }, "b" : { "x" : 3086, "y" : 147 }, "c" : { "x" : 3078, "y" : 144 }, "type" : "ARROW", "empty" : true, "centre" : { "x" : 3078, "y" : 144 } } }, { "edgeId" : 27407, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 2905, "y" : 161 }, "to" : { "x" : 2746, "y" : 68 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 2897, "y" : 161 }, "b" : { "x" : 2905, "y" : 161 }, "c" : { "x" : 2901, "y" : 154 }, "type" : "ARROW", "centre" : { "x" : 2901, "y" : 154 } } }, { "edgeId" : 27451, "type" : "INPUT", "segments" : [ { "from" : { "x" : 2916, "y" : 197 }, "to" : { "x" : 2871, "y" : 243 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 27413, "reactomeId" : 10389809, "displayName" : "GNAT1", "schemaClass" : "EntityWithAccessionedSequence", "renderableClass" : "Protein", "position" : { "x" : 1076, "y" : 575 }, "minX" : 1051, "maxX" : 1108, "minY" : 558, "maxY" : 586, "prop" : { "x" : 1051, "y" : 564, "width" : 51, "height" : 22 }, "textPosition" : { "x" : 1052, "y" : 564 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1102, "y" : 564 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1102, "y" : 564 } } }, "connectors" : [ { "edgeId" : 27412, "type" : "INPUT", "segments" : [ ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 27414, "reactomeId" : 174390, "displayName" : "L-Met", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 1243, "y" : 608 }, "minX" : 1186, "maxX" : 1270, "minY" : 574, "maxY" : 623, "prop" : { "x" : 1218, "y" : 593, "width" : 51, "height" : 30 }, "textPosition" : { "x" : 1223, "y" : 597 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1264, "y" : 598 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1264, "y" : 598 } } }, "connectors" : [ { "edgeId" : 27412, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 1215, "y" : 592 }, "to" : { "x" : 1186, "y" : 574 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 1207, "y" : 592 }, "b" : { "x" : 1215, "y" : 592 }, "c" : { "x" : 1211, "y" : 585 }, "type" : "ARROW", "centre" : { "x" : 1211, "y" : 585 } } } ] }, { "id" : 27415, "reactomeId" : 10389798, "displayName" : "GNAT1 (Met removed)", "schemaClass" : "EntityWithAccessionedSequence", "renderableClass" : "Protein", "position" : { "x" : 1281, "y" : 526 }, "minX" : 1186, "maxX" : 1330, "minY" : 495, "maxY" : 574, "prop" : { "x" : 1239, "y" : 508, "width" : 84, "height" : 36 }, "textPosition" : { "x" : 1239, "y" : 508 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1323, "y" : 508 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1323, "y" : 508 } } }, "connectors" : [ { "edgeId" : 27412, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 1245, "y" : 547 }, "to" : { "x" : 1186, "y" : 574 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 1240, "y" : 554 }, "b" : { "x" : 1245, "y" : 547 }, "c" : { "x" : 1237, "y" : 546 }, "type" : "ARROW", "centre" : { "x" : 1237, "y" : 546 } } }, { "edgeId" : 27417, "type" : "INPUT", "segments" : [ { "from" : { "x" : 1309, "y" : 505 }, "to" : { "x" : 1330, "y" : 495 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 27416, "reactomeId" : 10389823, "displayName" : "METAP1/2", "schemaClass" : "DefinedSet", "renderableClass" : "EntitySet", "position" : { "x" : 1147, "y" : 617 }, "minX" : 1112, "maxX" : 1183, "minY" : 582, "maxY" : 628, "prop" : { "x" : 1112, "y" : 606, "width" : 71, "height" : 22 }, "textPosition" : { "x" : 1113, "y" : 606 }, "bgColor" : { "r" : 204, "g" : 255, "b" : 255 }, "connectors" : [ { "edgeId" : 27412, "type" : "CATALYST", "segments" : [ { "from" : { "x" : 1147, "y" : 600 }, "to" : { "x" : 1147, "y" : 590 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "c" : { "x" : 1148, "y" : 586 }, "r" : 4, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1148, "y" : 586 } } } ] }, { "id" : 27418, "reactomeId" : 184174, "displayName" : "MYS-CoA", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 1265, "y" : 460 }, "minX" : 1230, "maxX" : 1330, "minY" : 444, "maxY" : 495, "prop" : { "x" : 1230, "y" : 445, "width" : 70, "height" : 31 }, "textPosition" : { "x" : 1234, "y" : 450 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1295, "y" : 450 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1295, "y" : 450 } } }, "connectors" : [ { "edgeId" : 27417, "type" : "INPUT", "segments" : [ { "from" : { "x" : 1293, "y" : 479 }, "to" : { "x" : 1330, "y" : 495 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 27419, "reactomeId" : 10337260, "displayName" : "N-(C14:0)-GNAT1", "schemaClass" : "EntityWithAccessionedSequence", "renderableClass" : "Protein", "position" : { "x" : 1407, "y" : 406 }, "minX" : 1348, "maxX" : 1472, "minY" : 389, "maxY" : 486, "prop" : { "x" : 1348, "y" : 395, "width" : 118, "height" : 22 }, "textPosition" : { "x" : 1351, "y" : 395 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1466, "y" : 395 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1466, "y" : 395 } } }, "connectors" : [ { "edgeId" : 27417, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 1405, "y" : 420 }, "to" : { "x" : 1399, "y" : 486 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 1408, "y" : 427 }, "b" : { "x" : 1405, "y" : 420 }, "c" : { "x" : 1400, "y" : 427 }, "type" : "ARROW", "centre" : { "x" : 1400, "y" : 427 } } } ] }, { "id" : 27420, "reactomeId" : 76194, "displayName" : "CoA-SH", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 1482, "y" : 463 }, "minX" : 1399, "maxX" : 1514, "minY" : 447, "maxY" : 486, "prop" : { "x" : 1451, "y" : 448, "width" : 62, "height" : 30 }, "textPosition" : { "x" : 1455, "y" : 452 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1508, "y" : 453 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1508, "y" : 453 } } }, "connectors" : [ { "edgeId" : 27417, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 1448, "y" : 471 }, "to" : { "x" : 1399, "y" : 486 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 1443, "y" : 477 }, "b" : { "x" : 1448, "y" : 471 }, "c" : { "x" : 1440, "y" : 469 }, "type" : "ARROW", "centre" : { "x" : 1440, "y" : 469 } } } ] }, { "id" : 27421, "reactomeId" : 10389804, "displayName" : "NMT1/2", "schemaClass" : "DefinedSet", "renderableClass" : "EntitySet", "position" : { "x" : 1361, "y" : 445 }, "minX" : 1332, "maxX" : 1390, "minY" : 434, "maxY" : 478, "prop" : { "x" : 1332, "y" : 434, "width" : 58, "height" : 22 }, "textPosition" : { "x" : 1334, "y" : 434 }, "connectors" : [ { "edgeId" : 27417, "type" : "CATALYST", "segments" : [ { "from" : { "x" : 1361, "y" : 462 }, "to" : { "x" : 1361, "y" : 470 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "c" : { "x" : 1361, "y" : 474 }, "r" : 4, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1361, "y" : 474 } } } ] }, { "id" : 27423, "reactomeId" : 2530498, "displayName" : "Gngt1", "schemaClass" : "EntityWithAccessionedSequence", "renderableClass" : "Protein", "position" : { "x" : 1076, "y" : 406 }, "minX" : 1050, "maxX" : 1108, "minY" : 389, "maxY" : 439, "prop" : { "x" : 1050, "y" : 395, "width" : 52, "height" : 22 }, "textPosition" : { "x" : 1053, "y" : 395 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1102, "y" : 395 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1102, "y" : 395 } } }, "connectors" : [ { "edgeId" : 27422, "type" : "INPUT", "segments" : [ { "from" : { "x" : 1084, "y" : 420 }, "to" : { "x" : 1101, "y" : 439 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 27424, "reactomeId" : 2530486, "displayName" : "FPP", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 1067, "y" : 455 }, "minX" : 1049, "maxX" : 1101, "minY" : 439, "maxY" : 470, "prop" : { "x" : 1049, "y" : 440, "width" : 37, "height" : 30 }, "textPosition" : { "x" : 1052, "y" : 444 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1081, "y" : 445 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1081, "y" : 445 } } }, "connectors" : [ { "edgeId" : 27422, "type" : "INPUT", "segments" : [ { "from" : { "x" : 1089, "y" : 446 }, "to" : { "x" : 1101, "y" : 439 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 27425, "reactomeId" : 10389674, "displayName" : "GNGT1", "schemaClass" : "EntityWithAccessionedSequence", "renderableClass" : "Protein", "position" : { "x" : 1205, "y" : 407 }, "minX" : 1155, "maxX" : 1259, "minY" : 390, "maxY" : 439, "prop" : { "x" : 1158, "y" : 396, "width" : 95, "height" : 22 }, "textPosition" : { "x" : 1180, "y" : 396 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1253, "y" : 396 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1253, "y" : 396 } } }, "connectors" : [ { "edgeId" : 27422, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 1187, "y" : 421 }, "to" : { "x" : 1155, "y" : 439 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 1183, "y" : 428 }, "b" : { "x" : 1187, "y" : 421 }, "c" : { "x" : 1179, "y" : 421 }, "type" : "ARROW", "centre" : { "x" : 1179, "y" : 421 } } } ] }, { "id" : 27426, "reactomeId" : 111294, "displayName" : "PPi", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 1185, "y" : 475 }, "minX" : 1155, "maxX" : 1203, "minY" : 439, "maxY" : 490, "prop" : { "x" : 1168, "y" : 460, "width" : 34, "height" : 30 }, "textPosition" : { "x" : 1171, "y" : 464 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1197, "y" : 465 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1197, "y" : 465 } } }, "connectors" : [ { "edgeId" : 27422, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 1172, "y" : 457 }, "to" : { "x" : 1155, "y" : 439 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 1164, "y" : 455 }, "b" : { "x" : 1172, "y" : 457 }, "c" : { "x" : 1170, "y" : 449 }, "type" : "ARROW", "centre" : { "x" : 1170, "y" : 449 } } } ] }, { "id" : 27427, "reactomeId" : 10389790, "displayName" : "FNTA:FNTB", "schemaClass" : "Complex", "renderableClass" : "Complex", "position" : { "x" : 1126, "y" : 507 }, "minX" : 1089, "maxX" : 1169, "minY" : 447, "maxY" : 518, "prop" : { "x" : 1089, "y" : 496, "width" : 74, "height" : 22 }, "textPosition" : { "x" : 1089, "y" : 497 }, "bgColor" : { "r" : 204, "g" : 255, "b" : 255 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1163, "y" : 496 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1163, "y" : 496 } } }, "connectors" : [ { "edgeId" : 27422, "type" : "CATALYST", "segments" : [ { "from" : { "x" : 1126, "y" : 493 }, "to" : { "x" : 1127, "y" : 455 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "c" : { "x" : 1127, "y" : 451 }, "r" : 4, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1127, "y" : 451 } } } ] }, { "id" : 27429, "reactomeId" : 113592, "displayName" : "ATP", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 1778, "y" : 434 }, "minX" : 1758, "maxX" : 1825, "minY" : 407, "maxY" : 449, "prop" : { "x" : 1758, "y" : 419, "width" : 40, "height" : 30 }, "textPosition" : { "x" : 1762, "y" : 423 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1793, "y" : 424 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1793, "y" : 424 } } }, "connectors" : [ { "edgeId" : 27428, "type" : "INPUT", "segments" : [ { "from" : { "x" : 1801, "y" : 422 }, "to" : { "x" : 1825, "y" : 407 } } ], "stoichiometry" : { "value" : 3, "shape" : { "a" : { "x" : 1807, "y" : 408 }, "b" : { "x" : 1819, "y" : 420 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 1813, "y" : 414 } } } } ] }, { "id" : 27430, "reactomeId" : 10337289, "displayName" : "at-retinyl-RHO", "schemaClass" : "EntityWithAccessionedSequence", "renderableClass" : "Protein", "position" : { "x" : 1376, "y" : 295 }, "minX" : 1329, "maxX" : 1825, "minY" : 278, "maxY" : 407, "prop" : { "x" : 1329, "y" : 284, "width" : 95, "height" : 22 }, "textPosition" : { "x" : 1330, "y" : 284 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1424, "y" : 284 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1424, "y" : 284 } } }, "connectors" : [ { "edgeId" : 27488, "type" : "OUTPUT", "segments" : [ ], "stoichiometry" : { "value" : 1 } }, { "edgeId" : 27428, "type" : "INPUT", "segments" : [ { "from" : { "x" : 1394, "y" : 309 }, "to" : { "x" : 1445, "y" : 336 } }, { "from" : { "x" : 1445, "y" : 336 }, "to" : { "x" : 1825, "y" : 407 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 27431, "reactomeId" : 29370, "displayName" : "ADP", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 1956, "y" : 455 }, "minX" : 1906, "maxX" : 1978, "minY" : 407, "maxY" : 470, "prop" : { "x" : 1936, "y" : 440, "width" : 41, "height" : 30 }, "textPosition" : { "x" : 1940, "y" : 444 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1972, "y" : 445 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1972, "y" : 445 } } }, "connectors" : [ { "edgeId" : 27428, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 1940, "y" : 437 }, "to" : { "x" : 1906, "y" : 407 } } ], "stoichiometry" : { "value" : 3, "shape" : { "a" : { "x" : 1917, "y" : 416 }, "b" : { "x" : 1929, "y" : 428 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 1923, "y" : 422 } } }, "endShape" : { "a" : { "x" : 1932, "y" : 435 }, "b" : { "x" : 1940, "y" : 437 }, "c" : { "x" : 1937, "y" : 429 }, "type" : "ARROW", "centre" : { "x" : 1937, "y" : 429 } } } ] }, { "id" : 27432, "reactomeId" : 10337827, "displayName" : "phospho-p-S334,338,343-at-retinyl-RHO", "schemaClass" : "EntityWithAccessionedSequence", "renderableClass" : "Protein", "position" : { "x" : 2011, "y" : 410 }, "minX" : 1906, "maxX" : 2076, "minY" : 386, "maxY" : 428, "prop" : { "x" : 1953, "y" : 392, "width" : 117, "height" : 36 }, "textPosition" : { "x" : 1954, "y" : 386 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 2070, "y" : 392 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 2070, "y" : 392 } } }, "connectors" : [ { "edgeId" : 27428, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 1950, "y" : 408 }, "to" : { "x" : 1906, "y" : 407 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 1943, "y" : 412 }, "b" : { "x" : 1950, "y" : 408 }, "c" : { "x" : 1943, "y" : 404 }, "type" : "ARROW", "centre" : { "x" : 1943, "y" : 404 } } } ] }, { "id" : 27433, "reactomeId" : 10390064, "displayName" : "GRK1,4,7", "schemaClass" : "DefinedSet", "renderableClass" : "EntitySet", "position" : { "x" : 1855, "y" : 329 }, "minX" : 1822, "maxX" : 1888, "minY" : 318, "maxY" : 399, "prop" : { "x" : 1822, "y" : 318, "width" : 66, "height" : 22 }, "textPosition" : { "x" : 1823, "y" : 318 }, "connectors" : [ { "edgeId" : 27428, "type" : "CATALYST", "segments" : [ { "from" : { "x" : 1857, "y" : 346 }, "to" : { "x" : 1868, "y" : 391 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "c" : { "x" : 1869, "y" : 395 }, "r" : 4, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1869, "y" : 395 } } } ] }, { "id" : 27434, "reactomeId" : 74016, "displayName" : "Ca2+", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 1829, "y" : 449 }, "minX" : 1804, "maxX" : 1868, "minY" : 410, "maxY" : 464, "prop" : { "x" : 1804, "y" : 434, "width" : 50, "height" : 30 }, "textPosition" : { "x" : 1808, "y" : 438 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1849, "y" : 439 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1849, "y" : 439 } } }, "connectors" : [ { "edgeId" : 27428, "type" : "INHIBITOR", "segments" : [ { "from" : { "x" : 1844, "y" : 431 }, "to" : { "x" : 1865, "y" : 413 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 1862, "y" : 410 }, "b" : { "x" : 1868, "y" : 416 }, "c" : { "x" : 1865, "y" : 413 }, "type" : "STOP", "centre" : { "x" : 1865, "y" : 413 } } } ] }, { "id" : 27435, "reactomeId" : 10337829, "displayName" : "p-MII:SAG", "schemaClass" : "Complex", "renderableClass" : "Complex", "position" : { "x" : 2188, "y" : 403 }, "minX" : 1875, "maxX" : 2636, "minY" : 381, "maxY" : 493, "prop" : { "x" : 2155, "y" : 387, "width" : 66, "height" : 32 }, "textPosition" : { "x" : 2155, "y" : 398 }, "bgColor" : { "r" : 204, "g" : 255, "b" : 255 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 2221, "y" : 387 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 2221, "y" : 387 } } }, "connectors" : [ { "edgeId" : 27428, "type" : "INHIBITOR", "segments" : [ { "from" : { "x" : 2175, "y" : 422 }, "to" : { "x" : 2122, "y" : 490 } }, { "from" : { "x" : 2122, "y" : 490 }, "to" : { "x" : 1946, "y" : 490 } }, { "from" : { "x" : 1946, "y" : 490 }, "to" : { "x" : 1878, "y" : 414 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 1875, "y" : 417 }, "b" : { "x" : 1881, "y" : 411 }, "c" : { "x" : 1878, "y" : 414 }, "type" : "STOP", "centre" : { "x" : 1878, "y" : 414 } } }, { "edgeId" : 27437, "type" : "INPUT", "segments" : [ { "from" : { "x" : 2224, "y" : 405 }, "to" : { "x" : 2238, "y" : 407 } } ], "stoichiometry" : { "value" : 1 } }, { "edgeId" : 27440, "type" : "INHIBITOR", "segments" : [ { "from" : { "x" : 2185, "y" : 422 }, "to" : { "x" : 2175, "y" : 493 } }, { "from" : { "x" : 2175, "y" : 493 }, "to" : { "x" : 2562, "y" : 493 } }, { "from" : { "x" : 2562, "y" : 493 }, "to" : { "x" : 2633, "y" : 415 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 2630, "y" : 412 }, "b" : { "x" : 2636, "y" : 418 }, "c" : { "x" : 2633, "y" : 415 }, "type" : "STOP", "centre" : { "x" : 2633, "y" : 415 } } } ] }, { "id" : 27436, "reactomeId" : 10390070, "displayName" : "S-farn-GRK1:RCVRN:Ca2+", "schemaClass" : "Complex", "renderableClass" : "Complex", "position" : { "x" : 1985, "y" : 579 }, "minX" : 1874, "maxX" : 2036, "minY" : 412, "maxY" : 597, "prop" : { "x" : 1941, "y" : 561, "width" : 89, "height" : 36 }, "textPosition" : { "x" : 1942, "y" : 562 }, "bgColor" : { "r" : 204, "g" : 255, "b" : 255 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 2030, "y" : 561 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 2030, "y" : 561 } } }, "connectors" : [ { "edgeId" : 27428, "type" : "INHIBITOR", "segments" : [ { "from" : { "x" : 1973, "y" : 558 }, "to" : { "x" : 1877, "y" : 414 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 1874, "y" : 416 }, "b" : { "x" : 1880, "y" : 412 }, "c" : { "x" : 1877, "y" : 414 }, "type" : "STOP", "centre" : { "x" : 1877, "y" : 414 } } } ] }, { "id" : 27438, "reactomeId" : 29356, "displayName" : "H2O", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 2207, "y" : 442 }, "minX" : 2186, "maxX" : 2238, "minY" : 407, "maxY" : 457, "prop" : { "x" : 2186, "y" : 427, "width" : 43, "height" : 30 }, "textPosition" : { "x" : 2190, "y" : 431 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 2224, "y" : 432 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 2224, "y" : 432 } } }, "connectors" : [ { "edgeId" : 27437, "type" : "INPUT", "segments" : [ { "from" : { "x" : 2220, "y" : 424 }, "to" : { "x" : 2238, "y" : 407 } } ], "stoichiometry" : { "value" : 1 } } ], "trivial" : true }, { "id" : 27439, "reactomeId" : 10390096, "displayName" : "p-RHO:SAG", "schemaClass" : "Complex", "renderableClass" : "Complex", "position" : { "x" : 2324, "y" : 407 }, "minX" : 2251, "maxX" : 2369, "minY" : 390, "maxY" : 418, "prop" : { "x" : 2286, "y" : 396, "width" : 77, "height" : 22 }, "textPosition" : { "x" : 2287, "y" : 397 }, "bgColor" : { "r" : 204, "g" : 255, "b" : 255 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 2363, "y" : 396 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 2363, "y" : 396 } } }, "connectors" : [ { "edgeId" : 27437, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 2283, "y" : 407 }, "to" : { "x" : 2251, "y" : 407 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 2276, "y" : 411 }, "b" : { "x" : 2283, "y" : 407 }, "c" : { "x" : 2276, "y" : 403 }, "type" : "ARROW", "centre" : { "x" : 2276, "y" : 403 } } } ] }, { "id" : 27441, "reactomeId" : 10337816, "displayName" : "phospho-p-S334,338,343-RHO", "schemaClass" : "EntityWithAccessionedSequence", "renderableClass" : "Protein", "position" : { "x" : 2506, "y" : 407 }, "minX" : 2448, "maxX" : 2609, "minY" : 383, "maxY" : 425, "prop" : { "x" : 2448, "y" : 389, "width" : 117, "height" : 36 }, "textPosition" : { "x" : 2449, "y" : 389 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 2565, "y" : 389 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 2565, "y" : 389 } } }, "connectors" : [ { "edgeId" : 27440, "type" : "INPUT", "segments" : [ { "from" : { "x" : 2568, "y" : 407 }, "to" : { "x" : 2609, "y" : 408 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 27442, "reactomeId" : 29356, "displayName" : "H2O", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 2562, "y" : 457 }, "minX" : 2541, "maxX" : 2609, "minY" : 408, "maxY" : 472, "prop" : { "x" : 2541, "y" : 442, "width" : 43, "height" : 30 }, "textPosition" : { "x" : 2545, "y" : 446 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 2579, "y" : 447 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 2579, "y" : 447 } } }, "connectors" : [ { "edgeId" : 27440, "type" : "INPUT", "segments" : [ { "from" : { "x" : 2576, "y" : 439 }, "to" : { "x" : 2609, "y" : 408 } } ], "stoichiometry" : { "value" : 3, "shape" : { "a" : { "x" : 2586, "y" : 417 }, "b" : { "x" : 2598, "y" : 429 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 2592, "y" : 423 } } } } ], "trivial" : true }, { "id" : 27443, "reactomeId" : 29372, "displayName" : "Pi", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 2744, "y" : 448 }, "minX" : 2680, "maxX" : 2759, "minY" : 408, "maxY" : 463, "prop" : { "x" : 2731, "y" : 433, "width" : 27, "height" : 30 }, "textPosition" : { "x" : 2735, "y" : 437 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 2753, "y" : 438 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 2753, "y" : 438 } } }, "connectors" : [ { "edgeId" : 27440, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 2728, "y" : 439 }, "to" : { "x" : 2680, "y" : 408 } } ], "stoichiometry" : { "value" : 3, "shape" : { "a" : { "x" : 2698, "y" : 417 }, "b" : { "x" : 2710, "y" : 429 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 2704, "y" : 423 } } }, "endShape" : { "a" : { "x" : 2720, "y" : 439 }, "b" : { "x" : 2728, "y" : 439 }, "c" : { "x" : 2724, "y" : 432 }, "type" : "ARROW", "centre" : { "x" : 2724, "y" : 432 } } } ] }, { "id" : 27444, "reactomeId" : 10337822, "displayName" : "PPEF1:Mg2+", "schemaClass" : "Complex", "renderableClass" : "Complex", "position" : { "x" : 2640, "y" : 523 }, "minX" : 2596, "maxX" : 2690, "minY" : 416, "maxY" : 534, "prop" : { "x" : 2596, "y" : 512, "width" : 88, "height" : 22 }, "textPosition" : { "x" : 2596, "y" : 513 }, "bgColor" : { "r" : 204, "g" : 255, "b" : 255 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 2684, "y" : 512 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 2684, "y" : 512 } } }, "connectors" : [ { "edgeId" : 27440, "type" : "CATALYST", "segments" : [ { "from" : { "x" : 2639, "y" : 509 }, "to" : { "x" : 2639, "y" : 424 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "c" : { "x" : 2639, "y" : 420 }, "r" : 4, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 2639, "y" : 420 } } } ] }, { "id" : 27445, "reactomeId" : 74016, "displayName" : "Ca2+", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 2708, "y" : 480 }, "minX" : 2645, "maxX" : 2734, "minY" : 414, "maxY" : 495, "prop" : { "x" : 2683, "y" : 465, "width" : 50, "height" : 30 }, "textPosition" : { "x" : 2687, "y" : 469 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 2728, "y" : 470 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 2728, "y" : 470 } } }, "connectors" : [ { "edgeId" : 27440, "type" : "ACTIVATOR", "segments" : [ { "from" : { "x" : 2693, "y" : 462 }, "to" : { "x" : 2645, "y" : 414 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 2653, "y" : 416 }, "b" : { "x" : 2645, "y" : 414 }, "c" : { "x" : 2647, "y" : 422 }, "type" : "ARROW", "empty" : true, "centre" : { "x" : 2647, "y" : 422 } } } ] }, { "id" : 27447, "reactomeId" : 29372, "displayName" : "Pi", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 1987, "y" : 224 }, "minX" : 1974, "maxX" : 2030, "minY" : 208, "maxY" : 253, "prop" : { "x" : 1974, "y" : 209, "width" : 27, "height" : 30 }, "textPosition" : { "x" : 1978, "y" : 213 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1996, "y" : 214 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1996, "y" : 214 } } }, "connectors" : [ { "edgeId" : 27446, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 2004, "y" : 233 }, "to" : { "x" : 2030, "y" : 253 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 2012, "y" : 234 }, "b" : { "x" : 2004, "y" : 233 }, "c" : { "x" : 2007, "y" : 240 }, "type" : "ARROW", "centre" : { "x" : 2007, "y" : 240 } } } ] }, { "id" : 27448, "reactomeId" : 10337277, "displayName" : "PDE6", "schemaClass" : "Complex", "renderableClass" : "Complex", "position" : { "x" : 1922, "y" : 292 }, "minX" : 1901, "maxX" : 2030, "minY" : 253, "maxY" : 303, "prop" : { "x" : 1901, "y" : 281, "width" : 42, "height" : 22 }, "textPosition" : { "x" : 1901, "y" : 282 }, "bgColor" : { "r" : 204, "g" : 255, "b" : 255 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1943, "y" : 281 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1943, "y" : 281 } } }, "connectors" : [ { "edgeId" : 27446, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 1946, "y" : 284 }, "to" : { "x" : 2030, "y" : 253 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 1951, "y" : 278 }, "b" : { "x" : 1946, "y" : 284 }, "c" : { "x" : 1954, "y" : 285 }, "type" : "ARROW", "centre" : { "x" : 1954, "y" : 285 } } } ] }, { "id" : 27449, "reactomeId" : 10390075, "displayName" : "GNAT1-GDP", "schemaClass" : "Complex", "renderableClass" : "Complex", "position" : { "x" : 1999, "y" : 295 }, "minX" : 1958, "maxX" : 2047, "minY" : 253, "maxY" : 306, "prop" : { "x" : 1958, "y" : 284, "width" : 83, "height" : 22 }, "textPosition" : { "x" : 1960, "y" : 285 }, "bgColor" : { "r" : 204, "g" : 255, "b" : 255 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 2041, "y" : 284 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 2041, "y" : 284 } } }, "connectors" : [ { "edgeId" : 27446, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 2007, "y" : 281 }, "to" : { "x" : 2030, "y" : 253 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 2008, "y" : 273 }, "b" : { "x" : 2007, "y" : 281 }, "c" : { "x" : 2014, "y" : 278 }, "type" : "ARROW", "centre" : { "x" : 2014, "y" : 278 } } } ] }, { "id" : 27450, "reactomeId" : 10390087, "displayName" : "RGS9-1:GNB5:RGS9BP", "schemaClass" : "Complex", "renderableClass" : "Complex", "position" : { "x" : 2339, "y" : 296 }, "minX" : 2267, "maxX" : 2393, "minY" : 272, "maxY" : 314, "prop" : { "x" : 2291, "y" : 278, "width" : 96, "height" : 36 }, "textPosition" : { "x" : 2291, "y" : 279 }, "bgColor" : { "r" : 204, "g" : 255, "b" : 255 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 2387, "y" : 278 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 2387, "y" : 278 } } }, "connectors" : [ { "edgeId" : 27446, "type" : "ACTIVATOR", "segments" : [ { "from" : { "x" : 2288, "y" : 296 }, "to" : { "x" : 2267, "y" : 296 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 2274, "y" : 292 }, "b" : { "x" : 2267, "y" : 296 }, "c" : { "x" : 2274, "y" : 300 }, "type" : "ARROW", "empty" : true, "centre" : { "x" : 2274, "y" : 300 } } } ] }, { "id" : 27452, "reactomeId" : 10390092, "displayName" : "GUCA", "schemaClass" : "DefinedSet", "renderableClass" : "EntitySet", "position" : { "x" : 2903, "y" : 297 }, "minX" : 2871, "maxX" : 2924, "minY" : 243, "maxY" : 308, "prop" : { "x" : 2882, "y" : 286, "width" : 42, "height" : 22 }, "textPosition" : { "x" : 2882, "y" : 286 }, "connectors" : [ { "edgeId" : 27451, "type" : "INPUT", "segments" : [ { "from" : { "x" : 2896, "y" : 280 }, "to" : { "x" : 2871, "y" : 243 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 27453, "reactomeId" : 10337799, "displayName" : "GUCA:Ca2+", "schemaClass" : "DefinedSet", "renderableClass" : "EntitySet", "position" : { "x" : 2798, "y" : 294 }, "minX" : 2719, "maxX" : 2839, "minY" : 247, "maxY" : 305, "prop" : { "x" : 2758, "y" : 283, "width" : 81, "height" : 22 }, "textPosition" : { "x" : 2758, "y" : 283 }, "bgColor" : { "r" : 204, "g" : 255, "b" : 255 }, "connectors" : [ { "edgeId" : 27451, "type" : "OUTPUT", "segments" : [ ], "stoichiometry" : { "value" : 1 } }, { "edgeId" : 27454, "type" : "INHIBITOR", "segments" : [ { "from" : { "x" : 2778, "y" : 277 }, "to" : { "x" : 2721, "y" : 251 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 2719, "y" : 255 }, "b" : { "x" : 2723, "y" : 247 }, "c" : { "x" : 2721, "y" : 251 }, "type" : "STOP", "centre" : { "x" : 2721, "y" : 251 } } } ] }, { "id" : 27455, "reactomeId" : 29438, "displayName" : "GTP", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 2794, "y" : 247 }, "minX" : 2774, "maxX" : 2816, "minY" : 231, "maxY" : 262, "prop" : { "x" : 2774, "y" : 232, "width" : 41, "height" : 30 }, "textPosition" : { "x" : 2778, "y" : 236 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 2810, "y" : 237 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 2810, "y" : 237 } } }, "connectors" : [ { "edgeId" : 27454, "type" : "INPUT", "segments" : [ ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 27456, "reactomeId" : 111294, "displayName" : "PPi", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 2611, "y" : 247 }, "minX" : 2594, "maxX" : 2663, "minY" : 231, "maxY" : 262, "prop" : { "x" : 2594, "y" : 232, "width" : 34, "height" : 30 }, "textPosition" : { "x" : 2597, "y" : 236 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 2623, "y" : 237 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 2623, "y" : 237 } } }, "connectors" : [ { "edgeId" : 27454, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 2631, "y" : 247 }, "to" : { "x" : 2663, "y" : 247 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 2638, "y" : 243 }, "b" : { "x" : 2631, "y" : 247 }, "c" : { "x" : 2638, "y" : 251 }, "type" : "ARROW", "centre" : { "x" : 2638, "y" : 251 } } } ] }, { "id" : 27457, "reactomeId" : 10337784, "displayName" : "GUCYs", "schemaClass" : "DefinedSet", "renderableClass" : "EntitySet", "position" : { "x" : 2715, "y" : 294 }, "minX" : 2691, "maxX" : 2740, "minY" : 255, "maxY" : 305, "prop" : { "x" : 2691, "y" : 283, "width" : 49, "height" : 22 }, "textPosition" : { "x" : 2691, "y" : 283 }, "connectors" : [ { "edgeId" : 27454, "type" : "CATALYST", "segments" : [ { "from" : { "x" : 2714, "y" : 277 }, "to" : { "x" : 2714, "y" : 263 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "c" : { "x" : 2713, "y" : 259 }, "r" : 4, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 2713, "y" : 259 } } } ] }, { "id" : 27458, "reactomeId" : 10337801, "displayName" : "GUCA1B", "schemaClass" : "EntityWithAccessionedSequence", "renderableClass" : "Protein", "position" : { "x" : 2680, "y" : 213 }, "minX" : 2651, "maxX" : 2716, "minY" : 196, "maxY" : 241, "prop" : { "x" : 2651, "y" : 202, "width" : 59, "height" : 22 }, "textPosition" : { "x" : 2651, "y" : 202 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 2710, "y" : 202 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 2710, "y" : 202 } } }, "connectors" : [ { "edgeId" : 27454, "type" : "ACTIVATOR", "segments" : [ { "from" : { "x" : 2690, "y" : 227 }, "to" : { "x" : 2706, "y" : 241 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 2698, "y" : 239 }, "b" : { "x" : 2706, "y" : 241 }, "c" : { "x" : 2703, "y" : 233 }, "type" : "ARROW", "empty" : true, "centre" : { "x" : 2703, "y" : 233 } } } ] }, { "id" : 27459, "reactomeId" : 10337803, "displayName" : "GUCA1A", "schemaClass" : "EntityWithAccessionedSequence", "renderableClass" : "Protein", "position" : { "x" : 2717, "y" : 186 }, "minX" : 2687, "maxX" : 2754, "minY" : 169, "maxY" : 238, "prop" : { "x" : 2687, "y" : 175, "width" : 61, "height" : 22 }, "textPosition" : { "x" : 2688, "y" : 175 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 2748, "y" : 175 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 2748, "y" : 175 } } }, "connectors" : [ { "edgeId" : 27454, "type" : "ACTIVATOR", "segments" : [ { "from" : { "x" : 2716, "y" : 200 }, "to" : { "x" : 2714, "y" : 238 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 2710, "y" : 231 }, "b" : { "x" : 2714, "y" : 238 }, "c" : { "x" : 2718, "y" : 231 }, "type" : "ARROW", "empty" : true, "centre" : { "x" : 2718, "y" : 231 } } } ] }, { "id" : 27460, "reactomeId" : 10337807, "displayName" : "GCAP2:Ca2+", "schemaClass" : "Complex", "renderableClass" : "Complex", "position" : { "x" : 2794, "y" : 174 }, "minX" : 2717, "maxX" : 2843, "minY" : 157, "maxY" : 244, "prop" : { "x" : 2751, "y" : 163, "width" : 86, "height" : 22 }, "textPosition" : { "x" : 2767, "y" : 150 }, "bgColor" : { "r" : 204, "g" : 255, "b" : 255 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 2837, "y" : 163 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 2837, "y" : 163 } } }, "connectors" : [ { "edgeId" : 27454, "type" : "INHIBITOR", "segments" : [ { "from" : { "x" : 2781, "y" : 188 }, "to" : { "x" : 2720, "y" : 241 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 2717, "y" : 238 }, "b" : { "x" : 2723, "y" : 244 }, "c" : { "x" : 2720, "y" : 241 }, "type" : "STOP", "centre" : { "x" : 2720, "y" : 241 } } } ] }, { "id" : 27461, "reactomeId" : 10337805, "displayName" : "GCAP1:Ca2+", "schemaClass" : "Complex", "renderableClass" : "Complex", "position" : { "x" : 2823, "y" : 202 }, "minX" : 2720, "maxX" : 2872, "minY" : 185, "maxY" : 248, "prop" : { "x" : 2780, "y" : 191, "width" : 86, "height" : 22 }, "textPosition" : { "x" : 2796, "y" : 178 }, "bgColor" : { "r" : 204, "g" : 255, "b" : 255 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 2866, "y" : 191 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 2866, "y" : 191 } } }, "connectors" : [ { "edgeId" : 27454, "type" : "INHIBITOR", "segments" : [ { "from" : { "x" : 2796, "y" : 216 }, "to" : { "x" : 2721, "y" : 244 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 2720, "y" : 240 }, "b" : { "x" : 2722, "y" : 248 }, "c" : { "x" : 2721, "y" : 244 }, "type" : "STOP", "centre" : { "x" : 2721, "y" : 244 } } } ] }, { "id" : 27464, "reactomeId" : 10340783, "displayName" : "CALM1:4xCa2+", "schemaClass" : "Complex", "renderableClass" : "Complex", "position" : { "x" : 2985, "y" : 119 }, "minX" : 2935, "maxX" : 3068, "minY" : 102, "maxY" : 130, "prop" : { "x" : 2935, "y" : 108, "width" : 101, "height" : 22 }, "textPosition" : { "x" : 2935, "y" : 109 }, "bgColor" : { "r" : 204, "g" : 255, "b" : 255 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 3036, "y" : 108 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 3036, "y" : 108 } } }, "connectors" : [ { "edgeId" : 27463, "type" : "INPUT", "segments" : [ { "from" : { "x" : 3039, "y" : 118 }, "to" : { "x" : 3068, "y" : 118 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 27465, "reactomeId" : 10392028, "displayName" : "CALM1:Ca2+:CNG channel", "schemaClass" : "Complex", "renderableClass" : "Complex", "position" : { "x" : 3095, "y" : 204 }, "minX" : 3035, "maxX" : 3161, "minY" : 180, "maxY" : 222, "prop" : { "x" : 3035, "y" : 186, "width" : 120, "height" : 36 }, "textPosition" : { "x" : 3035, "y" : 187 }, "bgColor" : { "r" : 204, "g" : 255, "b" : 255 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 3155, "y" : 186 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 3155, "y" : 186 } } }, "connectors" : [ { "edgeId" : 27463, "type" : "OUTPUT", "segments" : [ ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 27467, "reactomeId" : 6786220, "displayName" : "DHA", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 380, "y" : 573 }, "minX" : 359, "maxX" : 463, "minY" : 557, "maxY" : 588, "prop" : { "x" : 359, "y" : 558, "width" : 43, "height" : 30 }, "textPosition" : { "x" : 363, "y" : 562 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 397, "y" : 563 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 397, "y" : 563 } } }, "connectors" : [ { "edgeId" : 27466, "type" : "INPUT", "segments" : [ { "from" : { "x" : 405, "y" : 572 }, "to" : { "x" : 463, "y" : 572 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 27468, "reactomeId" : 29368, "displayName" : "O2", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 394, "y" : 612 }, "minX" : 377, "maxX" : 463, "minY" : 572, "maxY" : 627, "prop" : { "x" : 377, "y" : 597, "width" : 34, "height" : 30 }, "textPosition" : { "x" : 381, "y" : 601 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 406, "y" : 602 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 406, "y" : 602 } } }, "connectors" : [ { "edgeId" : 27466, "type" : "INPUT", "segments" : [ { "from" : { "x" : 414, "y" : 602 }, "to" : { "x" : 463, "y" : 572 } } ], "stoichiometry" : { "value" : 1 } } ], "trivial" : true }, { "id" : 27469, "reactomeId" : 29364, "displayName" : "NADPH", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 442, "y" : 618 }, "minX" : 413, "maxX" : 473, "minY" : 572, "maxY" : 633, "prop" : { "x" : 413, "y" : 603, "width" : 59, "height" : 30 }, "textPosition" : { "x" : 417, "y" : 607 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 467, "y" : 608 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 467, "y" : 608 } } }, "connectors" : [ { "edgeId" : 27466, "type" : "INPUT", "segments" : [ { "from" : { "x" : 448, "y" : 600 }, "to" : { "x" : 463, "y" : 572 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 27470, "reactomeId" : 70106, "displayName" : "H+", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 430, "y" : 549 }, "minX" : 412, "maxX" : 463, "minY" : 533, "maxY" : 572, "prop" : { "x" : 412, "y" : 534, "width" : 36, "height" : 30 }, "textPosition" : { "x" : 416, "y" : 538 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 443, "y" : 539 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 443, "y" : 539 } } }, "connectors" : [ { "edgeId" : 27466, "type" : "INPUT", "segments" : [ { "from" : { "x" : 451, "y" : 561 }, "to" : { "x" : 463, "y" : 572 } } ], "stoichiometry" : { "value" : 1 } } ], "trivial" : true }, { "id" : 27471, "reactomeId" : 6786225, "displayName" : "HDoHE", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 676, "y" : 576 }, "minX" : 550, "maxX" : 759, "minY" : 549, "maxY" : 602, "prop" : { "x" : 595, "y" : 550, "width" : 163, "height" : 52 }, "textPosition" : { "x" : 651, "y" : 565 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 753, "y" : 555 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 753, "y" : 555 } } }, "connectors" : [ { "edgeId" : 27466, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 592, "y" : 573 }, "to" : { "x" : 550, "y" : 572 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 585, "y" : 577 }, "b" : { "x" : 592, "y" : 573 }, "c" : { "x" : 585, "y" : 569 }, "type" : "ARROW", "centre" : { "x" : 585, "y" : 569 } } } ] }, { "id" : 27472, "reactomeId" : 29356, "displayName" : "H2O", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 595, "y" : 540 }, "minX" : 550, "maxX" : 618, "minY" : 524, "maxY" : 572, "prop" : { "x" : 574, "y" : 525, "width" : 43, "height" : 30 }, "textPosition" : { "x" : 578, "y" : 529 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 612, "y" : 530 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 612, "y" : 530 } } }, "connectors" : [ { "edgeId" : 27466, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 571, "y" : 555 }, "to" : { "x" : 550, "y" : 572 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 568, "y" : 562 }, "b" : { "x" : 571, "y" : 555 }, "c" : { "x" : 563, "y" : 556 }, "type" : "ARROW", "centre" : { "x" : 563, "y" : 556 } } } ], "trivial" : true }, { "id" : 27473, "reactomeId" : 29366, "displayName" : "NADP+", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 588, "y" : 615 }, "minX" : 550, "maxX" : 619, "minY" : 572, "maxY" : 630, "prop" : { "x" : 558, "y" : 600, "width" : 60, "height" : 30 }, "textPosition" : { "x" : 562, "y" : 604 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 613, "y" : 605 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 613, "y" : 605 } } }, "connectors" : [ { "edgeId" : 27466, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 574, "y" : 597 }, "to" : { "x" : 550, "y" : 572 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 566, "y" : 595 }, "b" : { "x" : 574, "y" : 597 }, "c" : { "x" : 572, "y" : 589 }, "type" : "ARROW", "centre" : { "x" : 572, "y" : 589 } } } ] }, { "id" : 27474, "reactomeId" : 10410930, "displayName" : "CYP4V2", "schemaClass" : "EntityWithAccessionedSequence", "renderableClass" : "Protein", "position" : { "x" : 508, "y" : 517 }, "minX" : 481, "maxX" : 542, "minY" : 500, "maxY" : 564, "prop" : { "x" : 481, "y" : 506, "width" : 55, "height" : 22 }, "textPosition" : { "x" : 481, "y" : 506 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 536, "y" : 506 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 536, "y" : 506 } } }, "connectors" : [ { "edgeId" : 27466, "type" : "CATALYST", "segments" : [ { "from" : { "x" : 508, "y" : 531 }, "to" : { "x" : 509, "y" : 556 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "c" : { "x" : 509, "y" : 560 }, "r" : 4, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 509, "y" : 560 } } } ] }, { "id" : 27476, "reactomeId" : 10335274, "displayName" : "CALM1", "schemaClass" : "EntityWithAccessionedSequence", "renderableClass" : "Protein", "position" : { "x" : 3000, "y" : 535 }, "minX" : 2952, "maxX" : 3031, "minY" : 518, "maxY" : 550, "prop" : { "x" : 2975, "y" : 524, "width" : 50, "height" : 22 }, "textPosition" : { "x" : 2976, "y" : 524 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 3025, "y" : 524 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 3025, "y" : 524 } } }, "connectors" : [ { "edgeId" : 27475, "type" : "INPUT", "segments" : [ { "from" : { "x" : 2972, "y" : 542 }, "to" : { "x" : 2952, "y" : 550 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 27477, "reactomeId" : 71284, "displayName" : "AdoMet", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 2986, "y" : 596 }, "minX" : 2952, "maxX" : 3018, "minY" : 550, "maxY" : 611, "prop" : { "x" : 2956, "y" : 581, "width" : 61, "height" : 30 }, "textPosition" : { "x" : 2959, "y" : 585 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 3012, "y" : 586 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 3012, "y" : 586 } } }, "connectors" : [ { "edgeId" : 27475, "type" : "INPUT", "segments" : [ { "from" : { "x" : 2974, "y" : 578 }, "to" : { "x" : 2952, "y" : 550 } } ], "stoichiometry" : { "value" : 3, "shape" : { "a" : { "x" : 2957, "y" : 558 }, "b" : { "x" : 2969, "y" : 570 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 2963, "y" : 564 } } } } ] }, { "id" : 27478, "reactomeId" : 71285, "displayName" : "AdoHcy", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 2824, "y" : 611 }, "minX" : 2794, "maxX" : 2856, "minY" : 550, "maxY" : 626, "prop" : { "x" : 2794, "y" : 596, "width" : 61, "height" : 30 }, "textPosition" : { "x" : 2797, "y" : 600 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 2850, "y" : 601 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 2850, "y" : 601 } } }, "connectors" : [ { "edgeId" : 27475, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 2830, "y" : 593 }, "to" : { "x" : 2852, "y" : 550 } } ], "stoichiometry" : { "value" : 3, "shape" : { "a" : { "x" : 2835, "y" : 565 }, "b" : { "x" : 2847, "y" : 577 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 2841, "y" : 571 } } }, "endShape" : { "a" : { "x" : 2830, "y" : 585 }, "b" : { "x" : 2830, "y" : 593 }, "c" : { "x" : 2837, "y" : 589 }, "type" : "ARROW", "centre" : { "x" : 2837, "y" : 589 } } } ] }, { "id" : 27479, "reactomeId" : 10410919, "displayName" : "Me3K116-CALM1", "schemaClass" : "EntityWithAccessionedSequence", "renderableClass" : "Protein", "position" : { "x" : 2760, "y" : 551 }, "minX" : 2704, "maxX" : 2852, "minY" : 534, "maxY" : 562, "prop" : { "x" : 2704, "y" : 540, "width" : 112, "height" : 22 }, "textPosition" : { "x" : 2705, "y" : 540 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 2816, "y" : 540 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 2816, "y" : 540 } } }, "connectors" : [ { "edgeId" : 27475, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 2819, "y" : 550 }, "to" : { "x" : 2852, "y" : 550 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 2826, "y" : 546 }, "b" : { "x" : 2819, "y" : 550 }, "c" : { "x" : 2826, "y" : 554 }, "type" : "ARROW", "centre" : { "x" : 2826, "y" : 554 } } } ] }, { "id" : 27480, "reactomeId" : 10410923, "displayName" : "CAMKMT", "schemaClass" : "EntityWithAccessionedSequence", "renderableClass" : "Protein", "position" : { "x" : 2897, "y" : 492 }, "minX" : 2864, "maxX" : 2936, "minY" : 475, "maxY" : 542, "prop" : { "x" : 2864, "y" : 481, "width" : 66, "height" : 23 }, "textPosition" : { "x" : 2868, "y" : 482 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 2930, "y" : 481 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 2930, "y" : 481 } } }, "connectors" : [ { "edgeId" : 27475, "type" : "CATALYST", "segments" : [ { "from" : { "x" : 2897, "y" : 507 }, "to" : { "x" : 2897, "y" : 534 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "c" : { "x" : 2897, "y" : 538 }, "r" : 4, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 2897, "y" : 538 } } } ] }, { "id" : 27483, "reactomeId" : 10362464, "displayName" : "OPN1SW", "schemaClass" : "EntityWithAccessionedSequence", "renderableClass" : "Protein", "position" : { "x" : 1498, "y" : 1188 }, "minX" : 1445, "maxX" : 1533, "minY" : 1171, "maxY" : 1297, "prop" : { "x" : 1469, "y" : 1177, "width" : 58, "height" : 22 }, "textPosition" : { "x" : 1473, "y" : 1171 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1527, "y" : 1177 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1527, "y" : 1177 } } }, "connectors" : [ { "edgeId" : 27482, "type" : "INPUT", "segments" : [ { "from" : { "x" : 1492, "y" : 1202 }, "to" : { "x" : 1445, "y" : 1297 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 27484, "reactomeId" : 10389346, "displayName" : "OPN1SW", "schemaClass" : "EntityWithAccessionedSequence", "renderableClass" : "Protein", "position" : { "x" : 1629, "y" : 1301 }, "minX" : 1479, "maxX" : 1690, "minY" : 1284, "maxY" : 1312, "prop" : { "x" : 1575, "y" : 1290, "width" : 109, "height" : 22 }, "textPosition" : { "x" : 1599, "y" : 1290 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1684, "y" : 1290 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1684, "y" : 1290 } } }, "connectors" : [ { "edgeId" : 27482, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 1572, "y" : 1295 }, "to" : { "x" : 1479, "y" : 1285 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 1565, "y" : 1298 }, "b" : { "x" : 1572, "y" : 1295 }, "c" : { "x" : 1566, "y" : 1290 }, "type" : "ARROW", "centre" : { "x" : 1566, "y" : 1290 } } } ] }, { "id" : 27486, "reactomeId" : 10362460, "displayName" : "OPN1LW", "schemaClass" : "EntityWithAccessionedSequence", "renderableClass" : "Protein", "position" : { "x" : 1316, "y" : 1230 }, "minX" : 1285, "maxX" : 1385, "minY" : 1213, "maxY" : 1259, "prop" : { "x" : 1285, "y" : 1219, "width" : 62, "height" : 22 }, "textPosition" : { "x" : 1286, "y" : 1219 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1347, "y" : 1219 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1347, "y" : 1219 } } }, "connectors" : [ { "edgeId" : 27485, "type" : "INPUT", "segments" : [ { "from" : { "x" : 1342, "y" : 1244 }, "to" : { "x" : 1385, "y" : 1259 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 27487, "reactomeId" : 10389343, "displayName" : "OPN1LW", "schemaClass" : "EntityWithAccessionedSequence", "renderableClass" : "Protein", "position" : { "x" : 1628, "y" : 1231 }, "minX" : 1510, "maxX" : 1691, "minY" : 1214, "maxY" : 1258, "prop" : { "x" : 1572, "y" : 1220, "width" : 113, "height" : 22 }, "textPosition" : { "x" : 1599, "y" : 1220 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1685, "y" : 1220 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1685, "y" : 1220 } } }, "connectors" : [ { "edgeId" : 27485, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 1579, "y" : 1245 }, "to" : { "x" : 1510, "y" : 1258 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 1573, "y" : 1250 }, "b" : { "x" : 1579, "y" : 1245 }, "c" : { "x" : 1571, "y" : 1242 }, "type" : "ARROW", "centre" : { "x" : 1571, "y" : 1242 } } } ] }, { "id" : 27489, "reactomeId" : 419777, "displayName" : "Photon", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 1303, "y" : 22 }, "minX" : 1276, "maxX" : 1331, "minY" : 10, "maxY" : 296, "prop" : { "x" : 1276, "y" : 11, "width" : 54, "height" : 22 }, "textPosition" : { "x" : 1276, "y" : 11 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1325, "y" : 16 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1325, "y" : 16 } } }, "connectors" : [ { "edgeId" : 27488, "type" : "INPUT", "segments" : [ { "from" : { "x" : 1303, "y" : 36 }, "to" : { "x" : 1304, "y" : 296 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 27534, "reactomeId" : 10390062, "displayName" : "S-farn-GRK1", "schemaClass" : "EntityWithAccessionedSequence", "renderableClass" : "Protein", "position" : { "x" : 1876, "y" : 489 }, "minX" : 1834, "maxX" : 1925, "minY" : 472, "maxY" : 500, "prop" : { "x" : 1834, "y" : 478, "width" : 85, "height" : 22 }, "textPosition" : { "x" : 1836, "y" : 478 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1919, "y" : 478 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1919, "y" : 478 } } }, "connectors" : [ ] }, { "id" : 27543, "reactomeId" : 10444870, "displayName" : "Retinoid metabolism and transport", "schemaClass" : "Pathway", "renderableClass" : "ProcessNode", "position" : { "x" : 63, "y" : 874 }, "minX" : 0, "maxX" : 127, "minY" : 836, "maxY" : 912, "prop" : { "x" : 0, "y" : 836, "width" : 127, "height" : 76 }, "textPosition" : { "x" : 3, "y" : 845 }, "connectors" : [ ] }, { "id" : 27302, "reactomeId" : 10388925, "displayName" : "TTR:RBP4:atROL", "schemaClass" : "Complex", "renderableClass" : "Complex", "position" : { "x" : 222, "y" : 872 }, "minX" : 169, "maxX" : 282, "minY" : 806, "maxY" : 883, "prop" : { "x" : 169, "y" : 861, "width" : 107, "height" : 22 }, "textPosition" : { "x" : 169, "y" : 862 }, "bgColor" : { "r" : 204, "g" : 255, "b" : 255 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 276, "y" : 861 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 276, "y" : 861 } } }, "connectors" : [ { "edgeId" : 27301, "type" : "INPUT", "segments" : [ { "from" : { "x" : 230, "y" : 858 }, "to" : { "x" : 275, "y" : 806 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 27303, "reactomeId" : 10389222, "displayName" : "STRA6", "schemaClass" : "EntityWithAccessionedSequence", "renderableClass" : "Protein", "position" : { "x" : 218, "y" : 771 }, "minX" : 195, "maxX" : 275, "minY" : 754, "maxY" : 806, "prop" : { "x" : 195, "y" : 760, "width" : 47, "height" : 22 }, "textPosition" : { "x" : 195, "y" : 760 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 242, "y" : 760 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 242, "y" : 760 } } }, "connectors" : [ { "edgeId" : 27301, "type" : "INPUT", "segments" : [ { "from" : { "x" : 235, "y" : 785 }, "to" : { "x" : 275, "y" : 806 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 27304, "reactomeId" : 10389224, "displayName" : "TTR:RBP4:atROL:STRA6", "schemaClass" : "Complex", "renderableClass" : "Complex", "position" : { "x" : 381, "y" : 806 }, "minX" : 327, "maxX" : 442, "minY" : 782, "maxY" : 824, "prop" : { "x" : 327, "y" : 788, "width" : 109, "height" : 36 }, "textPosition" : { "x" : 338, "y" : 789 }, "bgColor" : { "r" : 204, "g" : 255, "b" : 255 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 436, "y" : 788 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 436, "y" : 788 } } }, "connectors" : [ { "edgeId" : 27301, "type" : "OUTPUT", "segments" : [ ], "stoichiometry" : { "value" : 1 } }, { "edgeId" : 27305, "type" : "INPUT", "segments" : [ ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 27306, "reactomeId" : 10389226, "displayName" : "TTR:RBP4:STRA6", "schemaClass" : "Complex", "renderableClass" : "Complex", "position" : { "x" : 582, "y" : 806 }, "minX" : 499, "maxX" : 643, "minY" : 789, "maxY" : 817, "prop" : { "x" : 528, "y" : 795, "width" : 109, "height" : 22 }, "textPosition" : { "x" : 528, "y" : 796 }, "bgColor" : { "r" : 204, "g" : 255, "b" : 255 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 637, "y" : 795 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 637, "y" : 795 } } }, "connectors" : [ { "edgeId" : 27305, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 525, "y" : 806 }, "to" : { "x" : 499, "y" : 806 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 518, "y" : 810 }, "b" : { "x" : 525, "y" : 806 }, "c" : { "x" : 518, "y" : 802 }, "type" : "ARROW", "centre" : { "x" : 518, "y" : 802 } } } ] }, { "id" : 27307, "reactomeId" : 2473604, "displayName" : "atROL", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 500, "y" : 739 }, "minX" : 397, "maxX" : 527, "minY" : 723, "maxY" : 806, "prop" : { "x" : 475, "y" : 724, "width" : 51, "height" : 30 }, "textPosition" : { "x" : 478, "y" : 728 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 521, "y" : 729 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 521, "y" : 729 } } }, "connectors" : [ { "edgeId" : 27359, "type" : "OUTPUT", "segments" : [ ], "stoichiometry" : { "value" : 1 } }, { "edgeId" : 27305, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 499, "y" : 757 }, "to" : { "x" : 499, "y" : 806 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 503, "y" : 764 }, "b" : { "x" : 499, "y" : 757 }, "c" : { "x" : 495, "y" : 764 }, "type" : "ARROW", "centre" : { "x" : 495, "y" : 764 } } }, { "edgeId" : 27308, "type" : "INPUT", "segments" : [ { "from" : { "x" : 472, "y" : 739 }, "to" : { "x" : 397, "y" : 739 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 27309, "reactomeId" : 10337749, "displayName" : "Homologues of RBP1", "schemaClass" : "DefinedSet", "renderableClass" : "EntitySet", "position" : { "x" : 430, "y" : 703 }, "minX" : 397, "maxX" : 451, "minY" : 692, "maxY" : 739, "prop" : { "x" : 410, "y" : 692, "width" : 41, "height" : 22 }, "textPosition" : { "x" : 410, "y" : 665 }, "connectors" : [ { "edgeId" : 27308, "type" : "INPUT", "segments" : [ { "from" : { "x" : 419, "y" : 717 }, "to" : { "x" : 397, "y" : 739 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 27310, "reactomeId" : 10337751, "displayName" : "RBP1:atROL", "schemaClass" : "Complex", "renderableClass" : "Complex", "position" : { "x" : 320, "y" : 739 }, "minX" : 280, "maxX" : 367, "minY" : 627, "maxY" : 750, "prop" : { "x" : 280, "y" : 728, "width" : 81, "height" : 22 }, "textPosition" : { "x" : 280, "y" : 729 }, "bgColor" : { "r" : 204, "g" : 255, "b" : 255 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 361, "y" : 728 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 361, "y" : 728 } } }, "connectors" : [ { "edgeId" : 27308, "type" : "OUTPUT", "segments" : [ ], "stoichiometry" : { "value" : 1 } }, { "edgeId" : 27311, "type" : "INPUT", "segments" : [ { "from" : { "x" : 319, "y" : 725 }, "to" : { "x" : 318, "y" : 627 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 27312, "reactomeId" : 9982900, "displayName" : "RCOO-", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 223, "y" : 617 }, "minX" : 194, "maxX" : 318, "minY" : 601, "maxY" : 633, "prop" : { "x" : 194, "y" : 602, "width" : 58, "height" : 31 }, "textPosition" : { "x" : 200, "y" : 607 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 247, "y" : 607 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 247, "y" : 607 } } }, "connectors" : [ { "edgeId" : 27311, "type" : "INPUT", "segments" : [ { "from" : { "x" : 255, "y" : 620 }, "to" : { "x" : 318, "y" : 627 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 27313, "reactomeId" : 9982476, "displayName" : "atRE", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 282, "y" : 393 }, "minX" : 261, "maxX" : 305, "minY" : 345, "maxY" : 474, "prop" : { "x" : 261, "y" : 378, "width" : 43, "height" : 31 }, "textPosition" : { "x" : 264, "y" : 383 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 299, "y" : 383 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 299, "y" : 383 } } }, "connectors" : [ { "edgeId" : 27311, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 285, "y" : 412 }, "to" : { "x" : 302, "y" : 474 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 291, "y" : 418 }, "b" : { "x" : 285, "y" : 412 }, "c" : { "x" : 283, "y" : 420 }, "type" : "ARROW", "centre" : { "x" : 283, "y" : 420 } } }, { "edgeId" : 27316, "type" : "INPUT", "segments" : [ { "from" : { "x" : 283, "y" : 375 }, "to" : { "x" : 288, "y" : 345 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 27314, "reactomeId" : 10337749, "displayName" : "Homologues of RBP1", "schemaClass" : "DefinedSet", "renderableClass" : "EntitySet", "position" : { "x" : 247, "y" : 502 }, "minX" : 227, "maxX" : 302, "minY" : 474, "maxY" : 513, "prop" : { "x" : 227, "y" : 491, "width" : 41, "height" : 22 }, "textPosition" : { "x" : 227, "y" : 464 }, "connectors" : [ { "edgeId" : 27311, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 271, "y" : 491 }, "to" : { "x" : 302, "y" : 474 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 275, "y" : 484 }, "b" : { "x" : 271, "y" : 491 }, "c" : { "x" : 279, "y" : 491 }, "type" : "ARROW", "centre" : { "x" : 279, "y" : 491 } } } ] }, { "id" : 27315, "reactomeId" : 10372250, "displayName" : "LRAT", "schemaClass" : "EntityWithAccessionedSequence", "renderableClass" : "Protein", "position" : { "x" : 389, "y" : 514 }, "minX" : 324, "maxX" : 415, "minY" : 497, "maxY" : 535, "prop" : { "x" : 370, "y" : 503, "width" : 39, "height" : 22 }, "textPosition" : { "x" : 371, "y" : 503 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 409, "y" : 503 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 409, "y" : 503 } } }, "connectors" : [ { "edgeId" : 27311, "type" : "CATALYST", "segments" : [ { "from" : { "x" : 367, "y" : 519 }, "to" : { "x" : 332, "y" : 529 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "c" : { "x" : 328, "y" : 531 }, "r" : 4, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 328, "y" : 531 } } } ] }, { "id" : 27317, "reactomeId" : 29356, "displayName" : "H2O", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 412, "y" : 369 }, "minX" : 288, "maxX" : 435, "minY" : 345, "maxY" : 385, "prop" : { "x" : 391, "y" : 354, "width" : 43, "height" : 31 }, "textPosition" : { "x" : 395, "y" : 359 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 429, "y" : 359 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 429, "y" : 359 } } }, "connectors" : [ { "edgeId" : 27316, "type" : "INPUT", "segments" : [ { "from" : { "x" : 388, "y" : 364 }, "to" : { "x" : 288, "y" : 345 } } ], "stoichiometry" : { "value" : 1 } } ], "trivial" : true }, { "id" : 27318, "reactomeId" : 30927, "displayName" : "11cROL", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 327, "y" : 187 }, "minX" : 296, "maxX" : 401, "minY" : 171, "maxY" : 249, "prop" : { "x" : 296, "y" : 172, "width" : 62, "height" : 30 }, "textPosition" : { "x" : 300, "y" : 176 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 353, "y" : 177 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 353, "y" : 177 } } }, "connectors" : [ { "edgeId" : 27316, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 320, "y" : 205 }, "to" : { "x" : 302, "y" : 249 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 321, "y" : 213 }, "b" : { "x" : 320, "y" : 205 }, "c" : { "x" : 314, "y" : 210 }, "type" : "ARROW", "centre" : { "x" : 314, "y" : 210 } } }, { "edgeId" : 27323, "type" : "INPUT", "segments" : [ { "from" : { "x" : 361, "y" : 180 }, "to" : { "x" : 401, "y" : 171 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 27319, "reactomeId" : 9982478, "displayName" : "RCOO-", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 335, "y" : 331 }, "minX" : 302, "maxX" : 365, "minY" : 249, "maxY" : 347, "prop" : { "x" : 306, "y" : 316, "width" : 58, "height" : 31 }, "textPosition" : { "x" : 312, "y" : 321 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 359, "y" : 321 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 359, "y" : 321 } } }, "connectors" : [ { "edgeId" : 27316, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 328, "y" : 313 }, "to" : { "x" : 302, "y" : 249 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 322, "y" : 308 }, "b" : { "x" : 328, "y" : 313 }, "c" : { "x" : 329, "y" : 305 }, "type" : "ARROW", "centre" : { "x" : 329, "y" : 305 } } } ] }, { "id" : 27320, "reactomeId" : 70106, "displayName" : "H+", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 351, "y" : 232 }, "minX" : 302, "maxX" : 370, "minY" : 216, "maxY" : 249, "prop" : { "x" : 333, "y" : 217, "width" : 36, "height" : 30 }, "textPosition" : { "x" : 337, "y" : 221 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 364, "y" : 222 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 364, "y" : 222 } } }, "connectors" : [ { "edgeId" : 27316, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 330, "y" : 238 }, "to" : { "x" : 302, "y" : 249 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 325, "y" : 244 }, "b" : { "x" : 330, "y" : 238 }, "c" : { "x" : 322, "y" : 237 }, "type" : "ARROW", "centre" : { "x" : 322, "y" : 237 } } } ], "trivial" : true }, { "id" : 27321, "reactomeId" : 10389208, "displayName" : "RPE65", "schemaClass" : "EntityWithAccessionedSequence", "renderableClass" : "Protein", "position" : { "x" : 212, "y" : 289 }, "minX" : 188, "maxX" : 279, "minY" : 270, "maxY" : 302, "prop" : { "x" : 188, "y" : 276, "width" : 49, "height" : 26 }, "textPosition" : { "x" : 188, "y" : 278 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 237, "y" : 276 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 237, "y" : 276 } } }, "connectors" : [ { "edgeId" : 27316, "type" : "CATALYST", "segments" : [ { "from" : { "x" : 240, "y" : 288 }, "to" : { "x" : 271, "y" : 288 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "c" : { "x" : 275, "y" : 288 }, "r" : 4, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 275, "y" : 288 } } } ] }, { "id" : 27322, "reactomeId" : 10389213, "displayName" : "MYO7A", "schemaClass" : "EntityWithAccessionedSequence", "renderableClass" : "Protein", "position" : { "x" : 256, "y" : 224 }, "minX" : 231, "maxX" : 288, "minY" : 207, "maxY" : 280, "prop" : { "x" : 231, "y" : 213, "width" : 51, "height" : 22 }, "textPosition" : { "x" : 231, "y" : 213 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 282, "y" : 213 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 282, "y" : 213 } } }, "connectors" : [ { "edgeId" : 27316, "type" : "ACTIVATOR", "segments" : [ { "from" : { "x" : 261, "y" : 238 }, "to" : { "x" : 283, "y" : 280 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 276, "y" : 276 }, "b" : { "x" : 283, "y" : 280 }, "c" : { "x" : 283, "y" : 272 }, "type" : "ARROW", "empty" : true, "centre" : { "x" : 283, "y" : 272 } } } ] }, { "id" : 27324, "reactomeId" : 10337757, "displayName" : "RLBP1", "schemaClass" : "EntityWithAccessionedSequence", "renderableClass" : "Protein", "position" : { "x" : 353, "y" : 132 }, "minX" : 330, "maxX" : 836, "minY" : 75, "maxY" : 206, "prop" : { "x" : 330, "y" : 121, "width" : 47, "height" : 22 }, "textPosition" : { "x" : 330, "y" : 121 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 377, "y" : 121 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 377, "y" : 121 } } }, "connectors" : [ { "edgeId" : 27481, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 352, "y" : 118 }, "to" : { "x" : 352, "y" : 75 } }, { "from" : { "x" : 352, "y" : 75 }, "to" : { "x" : 806, "y" : 75 } }, { "from" : { "x" : 806, "y" : 75 }, "to" : { "x" : 836, "y" : 206 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 348, "y" : 111 }, "b" : { "x" : 352, "y" : 118 }, "c" : { "x" : 356, "y" : 111 }, "type" : "ARROW", "centre" : { "x" : 356, "y" : 111 } } }, { "edgeId" : 27323, "type" : "INPUT", "segments" : [ { "from" : { "x" : 366, "y" : 146 }, "to" : { "x" : 401, "y" : 171 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 27325, "reactomeId" : 10337759, "displayName" : "RLBP1:11cROL", "schemaClass" : "Complex", "renderableClass" : "Complex", "position" : { "x" : 486, "y" : 172 }, "minX" : 438, "maxX" : 575, "minY" : 155, "maxY" : 353, "prop" : { "x" : 438, "y" : 161, "width" : 97, "height" : 22 }, "textPosition" : { "x" : 438, "y" : 162 }, "bgColor" : { "r" : 204, "g" : 255, "b" : 255 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 535, "y" : 161 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 535, "y" : 161 } } }, "connectors" : [ { "edgeId" : 27332, "type" : "INPUT", "segments" : [ { "from" : { "x" : 487, "y" : 186 }, "to" : { "x" : 516, "y" : 353 } } ], "stoichiometry" : { "value" : 1 } }, { "edgeId" : 27323, "type" : "OUTPUT", "segments" : [ ], "stoichiometry" : { "value" : 1 } }, { "edgeId" : 27326, "type" : "INPUT", "segments" : [ { "from" : { "x" : 538, "y" : 169 }, "to" : { "x" : 575, "y" : 168 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 27327, "reactomeId" : 29366, "displayName" : "NADP+", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 537, "y" : 135 }, "minX" : 507, "maxX" : 575, "minY" : 119, "maxY" : 168, "prop" : { "x" : 507, "y" : 120, "width" : 60, "height" : 30 }, "textPosition" : { "x" : 511, "y" : 124 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 562, "y" : 125 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 562, "y" : 125 } } }, "connectors" : [ { "edgeId" : 27326, "type" : "INPUT", "segments" : [ { "from" : { "x" : 554, "y" : 153 }, "to" : { "x" : 575, "y" : 168 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 27328, "reactomeId" : 10337761, "displayName" : "RLBP1:11cRAL", "schemaClass" : "Complex", "renderableClass" : "Complex", "position" : { "x" : 764, "y" : 168 }, "minX" : 639, "maxX" : 818, "minY" : 151, "maxY" : 353, "prop" : { "x" : 716, "y" : 157, "width" : 96, "height" : 22 }, "textPosition" : { "x" : 716, "y" : 158 }, "bgColor" : { "r" : 204, "g" : 255, "b" : 255 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 812, "y" : 157 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 812, "y" : 157 } } }, "connectors" : [ { "edgeId" : 27332, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 761, "y" : 182 }, "to" : { "x" : 735, "y" : 306 } }, { "from" : { "x" : 735, "y" : 306 }, "to" : { "x" : 685, "y" : 353 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 763, "y" : 190 }, "b" : { "x" : 761, "y" : 182 }, "c" : { "x" : 756, "y" : 188 }, "type" : "ARROW", "centre" : { "x" : 756, "y" : 188 } } }, { "edgeId" : 27481, "type" : "INPUT", "segments" : [ ], "stoichiometry" : { "value" : 1 } }, { "edgeId" : 27326, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 713, "y" : 168 }, "to" : { "x" : 639, "y" : 168 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 706, "y" : 172 }, "b" : { "x" : 713, "y" : 168 }, "c" : { "x" : 706, "y" : 164 }, "type" : "ARROW", "centre" : { "x" : 706, "y" : 164 } } } ] }, { "id" : 27329, "reactomeId" : 70106, "displayName" : "H+", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 652, "y" : 129 }, "minX" : 634, "maxX" : 671, "minY" : 113, "maxY" : 168, "prop" : { "x" : 634, "y" : 114, "width" : 36, "height" : 30 }, "textPosition" : { "x" : 638, "y" : 118 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 665, "y" : 119 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 665, "y" : 119 } } }, "connectors" : [ { "edgeId" : 27326, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 647, "y" : 147 }, "to" : { "x" : 639, "y" : 168 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 648, "y" : 155 }, "b" : { "x" : 647, "y" : 147 }, "c" : { "x" : 641, "y" : 152 }, "type" : "ARROW", "centre" : { "x" : 641, "y" : 152 } } } ], "trivial" : true }, { "id" : 27330, "reactomeId" : 29364, "displayName" : "NADPH", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 705, "y" : 137 }, "minX" : 639, "maxX" : 736, "minY" : 121, "maxY" : 168, "prop" : { "x" : 676, "y" : 122, "width" : 59, "height" : 30 }, "textPosition" : { "x" : 680, "y" : 126 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 730, "y" : 127 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 730, "y" : 127 } } }, "connectors" : [ { "edgeId" : 27326, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 673, "y" : 150 }, "to" : { "x" : 639, "y" : 168 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 669, "y" : 157 }, "b" : { "x" : 673, "y" : 150 }, "c" : { "x" : 665, "y" : 150 }, "type" : "ARROW", "centre" : { "x" : 665, "y" : 150 } } } ] }, { "id" : 27331, "reactomeId" : 10337771, "displayName" : "RDH10,11", "schemaClass" : "DefinedSet", "renderableClass" : "EntitySet", "position" : { "x" : 606, "y" : 207 }, "minX" : 571, "maxX" : 642, "minY" : 176, "maxY" : 218, "prop" : { "x" : 571, "y" : 196, "width" : 71, "height" : 22 }, "textPosition" : { "x" : 571, "y" : 196 }, "connectors" : [ { "edgeId" : 27326, "type" : "CATALYST", "segments" : [ { "from" : { "x" : 605, "y" : 190 }, "to" : { "x" : 605, "y" : 184 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "c" : { "x" : 605, "y" : 180 }, "r" : 4, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 605, "y" : 180 } } } ] }, { "id" : 27333, "reactomeId" : 29360, "displayName" : "NAD+", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 478, "y" : 382 }, "minX" : 452, "maxX" : 516, "minY" : 353, "maxY" : 397, "prop" : { "x" : 452, "y" : 367, "width" : 53, "height" : 30 }, "textPosition" : { "x" : 456, "y" : 371 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 500, "y" : 372 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 500, "y" : 372 } } }, "connectors" : [ { "edgeId" : 27332, "type" : "INPUT", "segments" : [ { "from" : { "x" : 497, "y" : 364 }, "to" : { "x" : 516, "y" : 353 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 27334, "reactomeId" : 73473, "displayName" : "NADH", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 692, "y" : 398 }, "minX" : 666, "maxX" : 719, "minY" : 353, "maxY" : 413, "prop" : { "x" : 666, "y" : 383, "width" : 52, "height" : 30 }, "textPosition" : { "x" : 670, "y" : 387 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 713, "y" : 388 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 713, "y" : 388 } } }, "connectors" : [ { "edgeId" : 27332, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 689, "y" : 380 }, "to" : { "x" : 685, "y" : 353 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 684, "y" : 374 }, "b" : { "x" : 689, "y" : 380 }, "c" : { "x" : 692, "y" : 373 }, "type" : "ARROW", "centre" : { "x" : 692, "y" : 373 } } } ] }, { "id" : 27335, "reactomeId" : 70106, "displayName" : "H+", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 730, "y" : 366 }, "minX" : 685, "maxX" : 749, "minY" : 350, "maxY" : 381, "prop" : { "x" : 712, "y" : 351, "width" : 36, "height" : 30 }, "textPosition" : { "x" : 716, "y" : 355 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 743, "y" : 356 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 743, "y" : 356 } } }, "connectors" : [ { "edgeId" : 27332, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 709, "y" : 360 }, "to" : { "x" : 685, "y" : 353 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 701, "y" : 362 }, "b" : { "x" : 709, "y" : 360 }, "c" : { "x" : 703, "y" : 354 }, "type" : "ARROW", "centre" : { "x" : 703, "y" : 354 } } } ], "trivial" : true }, { "id" : 27336, "reactomeId" : 10389252, "displayName" : "RDH5(1-318)-like Proteins", "schemaClass" : "CandidateSet", "renderableClass" : "EntitySet", "position" : { "x" : 612, "y" : 306 }, "minX" : 552, "maxX" : 673, "minY" : 288, "maxY" : 345, "prop" : { "x" : 552, "y" : 288, "width" : 121, "height" : 36 }, "textPosition" : { "x" : 554, "y" : 288 }, "connectors" : [ { "edgeId" : 27332, "type" : "CATALYST", "segments" : [ { "from" : { "x" : 612, "y" : 330 }, "to" : { "x" : 612, "y" : 337 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "c" : { "x" : 612, "y" : 341 }, "r" : 4, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 612, "y" : 341 } } } ] }, { "id" : 27338, "reactomeId" : 8960974, "displayName" : "11cRAL", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 906, "y" : 207 }, "minX" : 836, "maxX" : 938, "minY" : 191, "maxY" : 222, "prop" : { "x" : 876, "y" : 192, "width" : 61, "height" : 30 }, "textPosition" : { "x" : 880, "y" : 196 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 932, "y" : 197 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 932, "y" : 197 } } }, "connectors" : [ { "edgeId" : 27337, "type" : "INPUT", "segments" : [ ], "stoichiometry" : { "value" : 1 } }, { "edgeId" : 27481, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 873, "y" : 206 }, "to" : { "x" : 836, "y" : 206 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 866, "y" : 210 }, "b" : { "x" : 873, "y" : 206 }, "c" : { "x" : 866, "y" : 202 }, "type" : "ARROW", "centre" : { "x" : 866, "y" : 202 } } } ] }, { "id" : 27339, "reactomeId" : 32737, "displayName" : "11cRAL", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 1088, "y" : 224 }, "minX" : 1058, "maxX" : 1127, "minY" : 208, "maxY" : 295, "prop" : { "x" : 1058, "y" : 209, "width" : 61, "height" : 30 }, "textPosition" : { "x" : 1062, "y" : 213 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1114, "y" : 214 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1114, "y" : 214 } } }, "connectors" : [ { "edgeId" : 27337, "type" : "OUTPUT", "segments" : [ ], "stoichiometry" : { "value" : 1 } }, { "edgeId" : 27341, "type" : "INPUT", "segments" : [ { "from" : { "x" : 1096, "y" : 242 }, "to" : { "x" : 1127, "y" : 295 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 27340, "reactomeId" : 10389259, "displayName" : "RBP3", "schemaClass" : "EntityWithAccessionedSequence", "renderableClass" : "Protein", "position" : { "x" : 991, "y" : 147 }, "minX" : 971, "maxX" : 1018, "minY" : 130, "maxY" : 198, "prop" : { "x" : 971, "y" : 136, "width" : 41, "height" : 22 }, "textPosition" : { "x" : 971, "y" : 136 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1012, "y" : 136 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1012, "y" : 136 } } }, "connectors" : [ { "edgeId" : 27337, "type" : "CATALYST", "segments" : [ { "from" : { "x" : 991, "y" : 161 }, "to" : { "x" : 991, "y" : 190 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "c" : { "x" : 991, "y" : 194 }, "r" : 4, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 991, "y" : 194 } } } ] }, { "id" : 27342, "reactomeId" : 2565923, "displayName" : "Rho", "schemaClass" : "EntityWithAccessionedSequence", "renderableClass" : "Protein", "position" : { "x" : 1092, "y" : 296 }, "minX" : 1075, "maxX" : 2680, "minY" : 279, "maxY" : 408, "prop" : { "x" : 1075, "y" : 285, "width" : 35, "height" : 22 }, "textPosition" : { "x" : 1076, "y" : 285 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1110, "y" : 285 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1110, "y" : 285 } } }, "connectors" : [ { "edgeId" : 27341, "type" : "INPUT", "segments" : [ { "from" : { "x" : 1113, "y" : 295 }, "to" : { "x" : 1127, "y" : 295 } } ], "stoichiometry" : { "value" : 1 } }, { "edgeId" : 27440, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 1096, "y" : 310 }, "to" : { "x" : 1122, "y" : 373 } }, { "from" : { "x" : 1122, "y" : 373 }, "to" : { "x" : 2657, "y" : 375 } }, { "from" : { "x" : 2657, "y" : 375 }, "to" : { "x" : 2680, "y" : 408 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 1102, "y" : 315 }, "b" : { "x" : 1096, "y" : 310 }, "c" : { "x" : 1095, "y" : 318 }, "type" : "ARROW", "centre" : { "x" : 1095, "y" : 318 } } } ] }, { "id" : 27343, "reactomeId" : 10337286, "displayName" : "11c-retinyl-RHO", "schemaClass" : "EntityWithAccessionedSequence", "renderableClass" : "Protein", "position" : { "x" : 1238, "y" : 298 }, "minX" : 1163, "maxX" : 1304, "minY" : 281, "maxY" : 309, "prop" : { "x" : 1185, "y" : 287, "width" : 106, "height" : 22 }, "textPosition" : { "x" : 1186, "y" : 287 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1291, "y" : 287 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1291, "y" : 287 } } }, "connectors" : [ { "edgeId" : 27341, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 1182, "y" : 295 }, "to" : { "x" : 1163, "y" : 295 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 1175, "y" : 299 }, "b" : { "x" : 1182, "y" : 295 }, "c" : { "x" : 1175, "y" : 291 }, "type" : "ARROW", "centre" : { "x" : 1175, "y" : 291 } } }, { "edgeId" : 27488, "type" : "INPUT", "segments" : [ { "from" : { "x" : 1294, "y" : 296 }, "to" : { "x" : 1304, "y" : 296 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 27344, "reactomeId" : 29356, "displayName" : "H2O", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 1205, "y" : 343 }, "minX" : 1163, "maxX" : 1228, "minY" : 295, "maxY" : 358, "prop" : { "x" : 1184, "y" : 328, "width" : 43, "height" : 30 }, "textPosition" : { "x" : 1188, "y" : 332 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1222, "y" : 333 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1222, "y" : 333 } } }, "connectors" : [ { "edgeId" : 27341, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 1191, "y" : 325 }, "to" : { "x" : 1163, "y" : 295 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 1183, "y" : 323 }, "b" : { "x" : 1191, "y" : 325 }, "c" : { "x" : 1189, "y" : 317 }, "type" : "ARROW", "centre" : { "x" : 1189, "y" : 317 } } } ], "trivial" : true }, { "id" : 27346, "reactomeId" : 2466098, "displayName" : "atRAL", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 1713, "y" : 413 }, "minX" : 1674, "maxX" : 2251, "minY" : 397, "maxY" : 520, "prop" : { "x" : 1688, "y" : 398, "width" : 50, "height" : 30 }, "textPosition" : { "x" : 1691, "y" : 402 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1733, "y" : 403 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1733, "y" : 403 } } }, "connectors" : [ { "edgeId" : 27345, "type" : "INPUT", "segments" : [ { "from" : { "x" : 1703, "y" : 431 }, "to" : { "x" : 1674, "y" : 477 } } ], "stoichiometry" : { "value" : 1 } }, { "edgeId" : 27437, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 1731, "y" : 431 }, "to" : { "x" : 1843, "y" : 516 } }, { "from" : { "x" : 1843, "y" : 516 }, "to" : { "x" : 2232, "y" : 520 } }, { "from" : { "x" : 2232, "y" : 520 }, "to" : { "x" : 2251, "y" : 407 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 1739, "y" : 432 }, "b" : { "x" : 1731, "y" : 431 }, "c" : { "x" : 1734, "y" : 438 }, "type" : "ARROW", "centre" : { "x" : 1734, "y" : 438 } } } ] }, { "id" : 27347, "reactomeId" : 113592, "displayName" : "ATP", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 1716, "y" : 469 }, "minX" : 1674, "maxX" : 1737, "minY" : 453, "maxY" : 484, "prop" : { "x" : 1696, "y" : 454, "width" : 40, "height" : 30 }, "textPosition" : { "x" : 1700, "y" : 458 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1731, "y" : 459 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1731, "y" : 459 } } }, "connectors" : [ { "edgeId" : 27345, "type" : "INPUT", "segments" : [ { "from" : { "x" : 1693, "y" : 472 }, "to" : { "x" : 1674, "y" : 477 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 27348, "reactomeId" : 29356, "displayName" : "H2O", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 1719, "y" : 506 }, "minX" : 1674, "maxX" : 1742, "minY" : 477, "maxY" : 521, "prop" : { "x" : 1698, "y" : 491, "width" : 43, "height" : 30 }, "textPosition" : { "x" : 1702, "y" : 495 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1736, "y" : 496 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1736, "y" : 496 } } }, "connectors" : [ { "edgeId" : 27345, "type" : "INPUT", "segments" : [ { "from" : { "x" : 1695, "y" : 492 }, "to" : { "x" : 1674, "y" : 477 } } ], "stoichiometry" : { "value" : 1 } } ], "trivial" : true }, { "id" : 27349, "reactomeId" : 29370, "displayName" : "ADP", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 1643, "y" : 571 }, "minX" : 1623, "maxX" : 1668, "minY" : 532, "maxY" : 586, "prop" : { "x" : 1623, "y" : 556, "width" : 41, "height" : 30 }, "textPosition" : { "x" : 1627, "y" : 560 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1659, "y" : 561 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1659, "y" : 561 } } }, "connectors" : [ { "edgeId" : 27345, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 1652, "y" : 553 }, "to" : { "x" : 1668, "y" : 532 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 1653, "y" : 545 }, "b" : { "x" : 1652, "y" : 553 }, "c" : { "x" : 1659, "y" : 550 }, "type" : "ARROW", "centre" : { "x" : 1659, "y" : 550 } } } ] }, { "id" : 27350, "reactomeId" : 29372, "displayName" : "Pi", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 1690, "y" : 582 }, "minX" : 1668, "maxX" : 1705, "minY" : 532, "maxY" : 597, "prop" : { "x" : 1677, "y" : 567, "width" : 27, "height" : 30 }, "textPosition" : { "x" : 1681, "y" : 571 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1699, "y" : 572 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1699, "y" : 572 } } }, "connectors" : [ { "edgeId" : 27345, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 1683, "y" : 564 }, "to" : { "x" : 1668, "y" : 532 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 1676, "y" : 559 }, "b" : { "x" : 1683, "y" : 564 }, "c" : { "x" : 1684, "y" : 556 }, "type" : "ARROW", "centre" : { "x" : 1684, "y" : 556 } } } ] }, { "id" : 27351, "reactomeId" : 975622, "displayName" : "atRAL", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 1775, "y" : 592 }, "minX" : 1668, "maxX" : 1888, "minY" : 532, "maxY" : 645, "prop" : { "x" : 1750, "y" : 577, "width" : 50, "height" : 30 }, "textPosition" : { "x" : 1753, "y" : 581 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1795, "y" : 582 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1795, "y" : 582 } } }, "connectors" : [ { "edgeId" : 27345, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 1747, "y" : 577 }, "to" : { "x" : 1668, "y" : 532 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 1739, "y" : 577 }, "b" : { "x" : 1747, "y" : 577 }, "c" : { "x" : 1743, "y" : 570 }, "type" : "ARROW", "centre" : { "x" : 1743, "y" : 570 } } }, { "edgeId" : 27353, "type" : "INPUT", "segments" : [ { "from" : { "x" : 1803, "y" : 603 }, "to" : { "x" : 1888, "y" : 645 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 27352, "reactomeId" : 10377793, "displayName" : "ABCA4", "schemaClass" : "EntityWithAccessionedSequence", "renderableClass" : "Protein", "position" : { "x" : 1648, "y" : 411 }, "minX" : 1624, "maxX" : 1678, "minY" : 394, "maxY" : 469, "prop" : { "x" : 1624, "y" : 400, "width" : 48, "height" : 22 }, "textPosition" : { "x" : 1624, "y" : 400 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1672, "y" : 400 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1672, "y" : 400 } } }, "connectors" : [ { "edgeId" : 27345, "type" : "CATALYST", "segments" : [ { "from" : { "x" : 1648, "y" : 425 }, "to" : { "x" : 1648, "y" : 461 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "c" : { "x" : 1648, "y" : 465 }, "r" : 4, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1648, "y" : 465 } } } ] }, { "id" : 27354, "reactomeId" : 70106, "displayName" : "H+", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 1864, "y" : 720 }, "minX" : 1846, "maxX" : 1888, "minY" : 645, "maxY" : 735, "prop" : { "x" : 1846, "y" : 705, "width" : 36, "height" : 30 }, "textPosition" : { "x" : 1850, "y" : 709 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1877, "y" : 710 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1877, "y" : 710 } } }, "connectors" : [ { "edgeId" : 27353, "type" : "INPUT", "segments" : [ { "from" : { "x" : 1868, "y" : 702 }, "to" : { "x" : 1888, "y" : 645 } } ], "stoichiometry" : { "value" : 1 } } ], "trivial" : true }, { "id" : 27355, "reactomeId" : 29364, "displayName" : "NADPH", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 1839, "y" : 675 }, "minX" : 1810, "maxX" : 1888, "minY" : 645, "maxY" : 690, "prop" : { "x" : 1810, "y" : 660, "width" : 59, "height" : 30 }, "textPosition" : { "x" : 1814, "y" : 664 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1864, "y" : 665 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1864, "y" : 665 } } }, "connectors" : [ { "edgeId" : 27353, "type" : "INPUT", "segments" : [ { "from" : { "x" : 1863, "y" : 657 }, "to" : { "x" : 1888, "y" : 645 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 27356, "reactomeId" : 2473615, "displayName" : "atROL", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 1878, "y" : 814 }, "minX" : 1853, "maxX" : 1918, "minY" : 749, "maxY" : 829, "prop" : { "x" : 1853, "y" : 799, "width" : 51, "height" : 30 }, "textPosition" : { "x" : 1856, "y" : 803 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1899, "y" : 804 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1899, "y" : 804 } } }, "connectors" : [ { "edgeId" : 27353, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 1887, "y" : 796 }, "to" : { "x" : 1918, "y" : 749 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 1887, "y" : 788 }, "b" : { "x" : 1887, "y" : 796 }, "c" : { "x" : 1894, "y" : 792 }, "type" : "ARROW", "centre" : { "x" : 1894, "y" : 792 } } }, { "edgeId" : 27359, "type" : "INPUT", "segments" : [ ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 27357, "reactomeId" : 29366, "displayName" : "NADP+", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 1868, "y" : 770 }, "minX" : 1838, "maxX" : 1918, "minY" : 749, "maxY" : 785, "prop" : { "x" : 1838, "y" : 755, "width" : 60, "height" : 30 }, "textPosition" : { "x" : 1842, "y" : 759 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1893, "y" : 760 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1893, "y" : 760 } } }, "connectors" : [ { "edgeId" : 27353, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 1901, "y" : 757 }, "to" : { "x" : 1918, "y" : 749 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 1906, "y" : 750 }, "b" : { "x" : 1901, "y" : 757 }, "c" : { "x" : 1909, "y" : 758 }, "type" : "ARROW", "centre" : { "x" : 1909, "y" : 758 } } } ] }, { "id" : 27358, "reactomeId" : 10389325, "displayName" : "RDH12", "schemaClass" : "EntityWithAccessionedSequence", "renderableClass" : "Protein", "position" : { "x" : 2192, "y" : 846 }, "minX" : 1915, "maxX" : 2224, "minY" : 713, "maxY" : 857, "prop" : { "x" : 2167, "y" : 835, "width" : 51, "height" : 22 }, "textPosition" : { "x" : 2167, "y" : 835 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 2218, "y" : 835 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 2218, "y" : 835 } } }, "connectors" : [ { "edgeId" : 27353, "type" : "CATALYST", "segments" : [ { "from" : { "x" : 2168, "y" : 832 }, "to" : { "x" : 1923, "y" : 719 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "c" : { "x" : 1919, "y" : 717 }, "r" : 4, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1919, "y" : 717 } } } ] }, { "id" : 27360, "reactomeId" : 10389259, "displayName" : "RBP3", "schemaClass" : "EntityWithAccessionedSequence", "renderableClass" : "Protein", "position" : { "x" : 993, "y" : 760 }, "minX" : 973, "maxX" : 1020, "minY" : 743, "maxY" : 787, "prop" : { "x" : 973, "y" : 749, "width" : 41, "height" : 22 }, "textPosition" : { "x" : 973, "y" : 749 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1014, "y" : 749 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1014, "y" : 749 } } }, "connectors" : [ { "edgeId" : 27359, "type" : "CATALYST", "segments" : [ { "from" : { "x" : 992, "y" : 774 }, "to" : { "x" : 992, "y" : 779 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "c" : { "x" : 992, "y" : 783 }, "r" : 4, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 992, "y" : 783 } } } ] }, { "id" : 27362, "reactomeId" : 2473607, "displayName" : "atROL", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 1295, "y" : 1036 }, "minX" : 1270, "maxX" : 1358, "minY" : 1020, "maxY" : 1052, "prop" : { "x" : 1270, "y" : 1021, "width" : 51, "height" : 30 }, "textPosition" : { "x" : 1273, "y" : 1025 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1316, "y" : 1026 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1316, "y" : 1026 } } }, "connectors" : [ { "edgeId" : 27361, "type" : "INPUT", "segments" : [ ], "stoichiometry" : { "value" : 1 } }, { "edgeId" : 27390, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 1324, "y" : 1042 }, "to" : { "x" : 1358, "y" : 1052 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 1332, "y" : 1040 }, "b" : { "x" : 1324, "y" : 1042 }, "c" : { "x" : 1330, "y" : 1048 }, "type" : "ARROW", "centre" : { "x" : 1330, "y" : 1048 } } } ] }, { "id" : 27363, "reactomeId" : 2473617, "displayName" : "atROL", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 814, "y" : 1036 }, "minX" : 759, "maxX" : 841, "minY" : 1020, "maxY" : 1051, "prop" : { "x" : 789, "y" : 1021, "width" : 51, "height" : 30 }, "textPosition" : { "x" : 792, "y" : 1025 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 835, "y" : 1026 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 835, "y" : 1026 } } }, "connectors" : [ { "edgeId" : 27361, "type" : "OUTPUT", "segments" : [ ], "stoichiometry" : { "value" : 1 } }, { "edgeId" : 27365, "type" : "INPUT", "segments" : [ { "from" : { "x" : 786, "y" : 1035 }, "to" : { "x" : 759, "y" : 1035 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 27364, "reactomeId" : 10389259, "displayName" : "RBP3", "schemaClass" : "EntityWithAccessionedSequence", "renderableClass" : "Protein", "position" : { "x" : 921, "y" : 1144 }, "minX" : 901, "maxX" : 948, "minY" : 1044, "maxY" : 1249, "prop" : { "x" : 901, "y" : 1133, "width" : 41, "height" : 22 }, "textPosition" : { "x" : 901, "y" : 1133 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 942, "y" : 1133 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 942, "y" : 1133 } } }, "connectors" : [ { "edgeId" : 27361, "type" : "CATALYST", "segments" : [ { "from" : { "x" : 921, "y" : 1130 }, "to" : { "x" : 923, "y" : 1052 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "c" : { "x" : 923, "y" : 1048 }, "r" : 4, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 923, "y" : 1048 } } }, { "edgeId" : 27374, "type" : "CATALYST", "segments" : [ { "from" : { "x" : 921, "y" : 1158 }, "to" : { "x" : 923, "y" : 1241 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "c" : { "x" : 923, "y" : 1245 }, "r" : 4, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 923, "y" : 1245 } } } ] }, { "id" : 27366, "reactomeId" : 10337757, "displayName" : "RLBP1", "schemaClass" : "EntityWithAccessionedSequence", "renderableClass" : "Protein", "position" : { "x" : 778, "y" : 1080 }, "minX" : 755, "maxX" : 808, "minY" : 1035, "maxY" : 1091, "prop" : { "x" : 755, "y" : 1069, "width" : 47, "height" : 22 }, "textPosition" : { "x" : 755, "y" : 1069 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 802, "y" : 1069 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 802, "y" : 1069 } } }, "connectors" : [ { "edgeId" : 27365, "type" : "INPUT", "segments" : [ { "from" : { "x" : 773, "y" : 1066 }, "to" : { "x" : 759, "y" : 1035 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 27367, "reactomeId" : 10389382, "displayName" : "RLBP1:atROL", "schemaClass" : "Complex", "renderableClass" : "Complex", "position" : { "x" : 656, "y" : 1037 }, "minX" : 613, "maxX" : 706, "minY" : 1020, "maxY" : 1048, "prop" : { "x" : 613, "y" : 1026, "width" : 87, "height" : 22 }, "textPosition" : { "x" : 613, "y" : 1027 }, "bgColor" : { "r" : 204, "g" : 255, "b" : 255 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 700, "y" : 1026 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 700, "y" : 1026 } } }, "connectors" : [ { "edgeId" : 27365, "type" : "OUTPUT", "segments" : [ ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 27369, "reactomeId" : 200993, "displayName" : "PALM-CoA", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 312, "y" : 1069 }, "minX" : 273, "maxX" : 383, "minY" : 1053, "maxY" : 1084, "prop" : { "x" : 273, "y" : 1054, "width" : 78, "height" : 30 }, "textPosition" : { "x" : 278, "y" : 1058 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 346, "y" : 1059 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 346, "y" : 1059 } } }, "connectors" : [ { "edgeId" : 27368, "type" : "INPUT", "segments" : [ { "from" : { "x" : 354, "y" : 1072 }, "to" : { "x" : 383, "y" : 1076 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 27370, "reactomeId" : 10337759, "displayName" : "RLBP1:11cROL", "schemaClass" : "Complex", "renderableClass" : "Complex", "position" : { "x" : 384, "y" : 1035 }, "minX" : 336, "maxX" : 439, "minY" : 1018, "maxY" : 1076, "prop" : { "x" : 336, "y" : 1024, "width" : 97, "height" : 22 }, "textPosition" : { "x" : 336, "y" : 1025 }, "bgColor" : { "r" : 204, "g" : 255, "b" : 255 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 433, "y" : 1024 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 433, "y" : 1024 } } }, "connectors" : [ { "edgeId" : 27368, "type" : "INPUT", "segments" : [ { "from" : { "x" : 383, "y" : 1049 }, "to" : { "x" : 383, "y" : 1076 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 27371, "reactomeId" : 76194, "displayName" : "CoA-SH", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 325, "y" : 1149 }, "minX" : 294, "maxX" : 383, "minY" : 1133, "maxY" : 1164, "prop" : { "x" : 294, "y" : 1134, "width" : 62, "height" : 30 }, "textPosition" : { "x" : 298, "y" : 1138 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 351, "y" : 1139 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 351, "y" : 1139 } } }, "connectors" : [ { "edgeId" : 27368, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 359, "y" : 1143 }, "to" : { "x" : 383, "y" : 1139 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 365, "y" : 1138 }, "b" : { "x" : 359, "y" : 1143 }, "c" : { "x" : 366, "y" : 1146 }, "type" : "ARROW", "centre" : { "x" : 366, "y" : 1146 } } } ] }, { "id" : 27372, "reactomeId" : 10389360, "displayName" : "RLBP1:11cRPALM", "schemaClass" : "Complex", "renderableClass" : "Complex", "position" : { "x" : 384, "y" : 1191 }, "minX" : 329, "maxX" : 445, "minY" : 1139, "maxY" : 1202, "prop" : { "x" : 329, "y" : 1180, "width" : 110, "height" : 22 }, "textPosition" : { "x" : 348, "y" : 1167 }, "bgColor" : { "r" : 204, "g" : 255, "b" : 255 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 439, "y" : 1180 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 439, "y" : 1180 } } }, "connectors" : [ { "edgeId" : 27368, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 383, "y" : 1177 }, "to" : { "x" : 383, "y" : 1139 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 379, "y" : 1170 }, "b" : { "x" : 383, "y" : 1177 }, "c" : { "x" : 387, "y" : 1170 }, "type" : "ARROW", "centre" : { "x" : 387, "y" : 1170 } } } ] }, { "id" : 27373, "reactomeId" : 10389364, "displayName" : "AWAT2", "schemaClass" : "EntityWithAccessionedSequence", "renderableClass" : "Protein", "position" : { "x" : 447, "y" : 1105 }, "minX" : 391, "maxX" : 479, "minY" : 1088, "maxY" : 1116, "prop" : { "x" : 422, "y" : 1094, "width" : 51, "height" : 22 }, "textPosition" : { "x" : 422, "y" : 1094 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 473, "y" : 1094 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 473, "y" : 1094 } } }, "connectors" : [ { "edgeId" : 27368, "type" : "CATALYST", "segments" : [ { "from" : { "x" : 419, "y" : 1105 }, "to" : { "x" : 399, "y" : 1105 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "c" : { "x" : 395, "y" : 1105 }, "r" : 4, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 395, "y" : 1105 } } } ] }, { "id" : 27375, "reactomeId" : 2473606, "displayName" : "11cROL", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 774, "y" : 1258 }, "minX" : 743, "maxX" : 806, "minY" : 1242, "maxY" : 1273, "prop" : { "x" : 743, "y" : 1243, "width" : 62, "height" : 30 }, "textPosition" : { "x" : 747, "y" : 1247 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 800, "y" : 1248 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 800, "y" : 1248 } } }, "connectors" : [ { "edgeId" : 27374, "type" : "INPUT", "segments" : [ ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 27376, "reactomeId" : 2473611, "displayName" : "11cROL", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 1038, "y" : 1274 }, "minX" : 1007, "maxX" : 1070, "minY" : 1258, "maxY" : 1289, "prop" : { "x" : 1007, "y" : 1259, "width" : 62, "height" : 30 }, "textPosition" : { "x" : 1011, "y" : 1263 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1064, "y" : 1264 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1064, "y" : 1264 } } }, "connectors" : [ { "edgeId" : 27374, "type" : "OUTPUT", "segments" : [ ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 27378, "reactomeId" : 10362460, "displayName" : "OPN1LW", "schemaClass" : "EntityWithAccessionedSequence", "renderableClass" : "Protein", "position" : { "x" : 1417, "y" : 1218 }, "minX" : 1388, "maxX" : 1452, "minY" : 1201, "maxY" : 1273, "prop" : { "x" : 1388, "y" : 1207, "width" : 58, "height" : 22 }, "textPosition" : { "x" : 1393, "y" : 1201 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1446, "y" : 1207 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1446, "y" : 1207 } } }, "connectors" : [ { "edgeId" : 27377, "type" : "INPUT", "segments" : [ { "from" : { "x" : 1413, "y" : 1232 }, "to" : { "x" : 1397, "y" : 1273 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 27379, "reactomeId" : 32737, "displayName" : "11cRAL", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 1272, "y" : 1273 }, "minX" : 1242, "maxX" : 1445, "minY" : 1257, "maxY" : 1297, "prop" : { "x" : 1242, "y" : 1258, "width" : 61, "height" : 30 }, "textPosition" : { "x" : 1246, "y" : 1262 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1298, "y" : 1263 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1298, "y" : 1263 } } }, "connectors" : [ { "edgeId" : 27482, "type" : "INPUT", "segments" : [ { "from" : { "x" : 1306, "y" : 1277 }, "to" : { "x" : 1445, "y" : 1297 } } ], "stoichiometry" : { "value" : 1 } }, { "edgeId" : 27485, "type" : "INPUT", "segments" : [ { "from" : { "x" : 1306, "y" : 1269 }, "to" : { "x" : 1385, "y" : 1259 } } ], "stoichiometry" : { "value" : 1 } }, { "edgeId" : 27377, "type" : "INPUT", "segments" : [ { "from" : { "x" : 1306, "y" : 1273 }, "to" : { "x" : 1397, "y" : 1273 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 27380, "reactomeId" : 10389343, "displayName" : "OPN1LW", "schemaClass" : "EntityWithAccessionedSequence", "renderableClass" : "Protein", "position" : { "x" : 1629, "y" : 1266 }, "minX" : 1496, "maxX" : 1690, "minY" : 1249, "maxY" : 1277, "prop" : { "x" : 1575, "y" : 1255, "width" : 109, "height" : 22 }, "textPosition" : { "x" : 1600, "y" : 1255 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1684, "y" : 1255 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1684, "y" : 1255 } } }, "connectors" : [ { "edgeId" : 27377, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 1572, "y" : 1268 }, "to" : { "x" : 1496, "y" : 1273 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 1565, "y" : 1272 }, "b" : { "x" : 1572, "y" : 1268 }, "c" : { "x" : 1565, "y" : 1264 }, "type" : "ARROW", "centre" : { "x" : 1565, "y" : 1264 } } } ] }, { "id" : 27381, "reactomeId" : 29356, "displayName" : "H2O", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 1515, "y" : 1319 }, "minX" : 1479, "maxX" : 1538, "minY" : 1258, "maxY" : 1334, "prop" : { "x" : 1494, "y" : 1304, "width" : 43, "height" : 30 }, "textPosition" : { "x" : 1498, "y" : 1308 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1532, "y" : 1309 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1532, "y" : 1309 } } }, "connectors" : [ { "edgeId" : 27482, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 1499, "y" : 1301 }, "to" : { "x" : 1479, "y" : 1285 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 1491, "y" : 1300 }, "b" : { "x" : 1499, "y" : 1301 }, "c" : { "x" : 1496, "y" : 1294 }, "type" : "ARROW", "centre" : { "x" : 1496, "y" : 1294 } } }, { "edgeId" : 27485, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 1513, "y" : 1301 }, "to" : { "x" : 1510, "y" : 1258 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 1509, "y" : 1294 }, "b" : { "x" : 1513, "y" : 1301 }, "c" : { "x" : 1517, "y" : 1294 }, "type" : "ARROW", "centre" : { "x" : 1517, "y" : 1294 } } }, { "edgeId" : 27377, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 1508, "y" : 1301 }, "to" : { "x" : 1496, "y" : 1273 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 1502, "y" : 1296 }, "b" : { "x" : 1508, "y" : 1301 }, "c" : { "x" : 1509, "y" : 1293 }, "type" : "ARROW", "centre" : { "x" : 1509, "y" : 1293 } } } ], "trivial" : true }, { "id" : 27383, "reactomeId" : 10389348, "displayName" : "11c-retinyl-cone opsins", "schemaClass" : "DefinedSet", "renderableClass" : "EntitySet", "position" : { "x" : 1807, "y" : 1260 }, "minX" : 1752, "maxX" : 1932, "minY" : 1242, "maxY" : 1278, "prop" : { "x" : 1752, "y" : 1242, "width" : 111, "height" : 36 }, "textPosition" : { "x" : 1752, "y" : 1242 }, "bgColor" : { "r" : 204, "g" : 255, "b" : 255 }, "connectors" : [ { "edgeId" : 27382, "type" : "INPUT", "segments" : [ { "from" : { "x" : 1869, "y" : 1260 }, "to" : { "x" : 1932, "y" : 1260 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 27384, "reactomeId" : 419777, "displayName" : "Photon", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 1869, "y" : 1378 }, "minX" : 1842, "maxX" : 1932, "minY" : 1260, "maxY" : 1389, "prop" : { "x" : 1842, "y" : 1367, "width" : 54, "height" : 22 }, "textPosition" : { "x" : 1842, "y" : 1367 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1891, "y" : 1372 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1891, "y" : 1372 } } }, "connectors" : [ { "edgeId" : 27382, "type" : "INPUT", "segments" : [ { "from" : { "x" : 1874, "y" : 1364 }, "to" : { "x" : 1932, "y" : 1260 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 27385, "reactomeId" : 10389356, "displayName" : "at-retinyl-cone opsins", "schemaClass" : "DefinedSet", "renderableClass" : "EntitySet", "position" : { "x" : 1930, "y" : 1125 }, "minX" : 1696, "maxX" : 1981, "minY" : 1108, "maxY" : 1143, "prop" : { "x" : 1879, "y" : 1108, "width" : 102, "height" : 35 }, "textPosition" : { "x" : 1879, "y" : 1108 }, "bgColor" : { "r" : 204, "g" : 255, "b" : 255 }, "connectors" : [ { "edgeId" : 27382, "type" : "OUTPUT", "segments" : [ ], "stoichiometry" : { "value" : 1 } }, { "edgeId" : 27386, "type" : "INPUT", "segments" : [ { "from" : { "x" : 1873, "y" : 1121 }, "to" : { "x" : 1696, "y" : 1111 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 27387, "reactomeId" : 29356, "displayName" : "H2O", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 1756, "y" : 1078 }, "minX" : 1696, "maxX" : 1779, "minY" : 1062, "maxY" : 1111, "prop" : { "x" : 1735, "y" : 1063, "width" : 43, "height" : 30 }, "textPosition" : { "x" : 1739, "y" : 1067 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1773, "y" : 1068 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1773, "y" : 1068 } } }, "connectors" : [ { "edgeId" : 27386, "type" : "INPUT", "segments" : [ { "from" : { "x" : 1732, "y" : 1089 }, "to" : { "x" : 1696, "y" : 1111 } } ], "stoichiometry" : { "value" : 1 } } ], "trivial" : true }, { "id" : 27388, "reactomeId" : 10389424, "displayName" : "Cone apo-opsins", "schemaClass" : "DefinedSet", "renderableClass" : "EntitySet", "position" : { "x" : 1395, "y" : 1150 }, "minX" : 1338, "maxX" : 1600, "minY" : 1111, "maxY" : 1161, "prop" : { "x" : 1338, "y" : 1139, "width" : 114, "height" : 22 }, "textPosition" : { "x" : 1338, "y" : 1139 }, "connectors" : [ { "edgeId" : 27386, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 1458, "y" : 1139 }, "to" : { "x" : 1600, "y" : 1111 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 1464, "y" : 1134 }, "b" : { "x" : 1458, "y" : 1139 }, "c" : { "x" : 1466, "y" : 1142 }, "type" : "ARROW", "centre" : { "x" : 1466, "y" : 1142 } } } ] }, { "id" : 27389, "reactomeId" : 975622, "displayName" : "atRAL", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 1550, "y" : 1053 }, "minX" : 1467, "maxX" : 1600, "minY" : 1037, "maxY" : 1111, "prop" : { "x" : 1525, "y" : 1038, "width" : 50, "height" : 30 }, "textPosition" : { "x" : 1528, "y" : 1042 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1570, "y" : 1043 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1570, "y" : 1043 } } }, "connectors" : [ { "edgeId" : 27386, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 1562, "y" : 1071 }, "to" : { "x" : 1600, "y" : 1111 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 1570, "y" : 1073 }, "b" : { "x" : 1562, "y" : 1071 }, "c" : { "x" : 1564, "y" : 1079 }, "type" : "ARROW", "centre" : { "x" : 1564, "y" : 1079 } } }, { "edgeId" : 27390, "type" : "INPUT", "segments" : [ { "from" : { "x" : 1522, "y" : 1052 }, "to" : { "x" : 1467, "y" : 1052 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 27391, "reactomeId" : 29364, "displayName" : "NADPH", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 1497, "y" : 1080 }, "minX" : 1467, "maxX" : 1528, "minY" : 1052, "maxY" : 1095, "prop" : { "x" : 1468, "y" : 1065, "width" : 59, "height" : 30 }, "textPosition" : { "x" : 1472, "y" : 1069 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1522, "y" : 1070 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1522, "y" : 1070 } } }, "connectors" : [ { "edgeId" : 27390, "type" : "INPUT", "segments" : [ { "from" : { "x" : 1480, "y" : 1062 }, "to" : { "x" : 1467, "y" : 1052 } } ], "stoichiometry" : { "value" : 1 } } ] } ], "edges" : [ { "id" : 27395, "reactomeId" : 10389680, "displayName" : "Gt-GTP dissociates to GNAT1-GTP and GNB1:GNGT1", "schemaClass" : "Reaction", "renderableClass" : "Reaction", "position" : { "x" : 1658, "y" : 286 }, "minX" : 1644, "maxX" : 1678, "minY" : 277, "maxY" : 289, "reactionType" : "dissociation", "segments" : [ { "from" : { "x" : 1644, "y" : 289 }, "to" : { "x" : 1658, "y" : 286 } }, { "from" : { "x" : 1658, "y" : 286 }, "to" : { "x" : 1672, "y" : 283 } } ], "reactionShape" : { "c" : { "x" : 1658, "y" : 286 }, "r" : 5, "r1" : 3, "type" : "DOUBLE_CIRCLE", "empty" : true, "centre" : { "x" : 1658, "y" : 286 } }, "inputs" : [ { "id" : 27396 } ], "outputs" : [ { "id" : 27397, "points" : [ { "x" : 1717, "y" : 306 }, { "x" : 1699, "y" : 313 } ] }, { "id" : 27398, "points" : [ { "x" : 1804, "y" : 283 }, { "x" : 1723, "y" : 267 } ] } ] }, { "id" : 27332, "reactomeId" : 10389255, "displayName" : "RDH5 oxidises 11cROL to 11cRAL", "schemaClass" : "Reaction", "renderableClass" : "Reaction", "position" : { "x" : 612, "y" : 353 }, "minX" : 516, "maxX" : 685, "minY" : 347, "maxY" : 359, "reactionType" : "transition", "segments" : [ { "from" : { "x" : 516, "y" : 353 }, "to" : { "x" : 612, "y" : 353 } }, { "from" : { "x" : 612, "y" : 353 }, "to" : { "x" : 685, "y" : 353 } } ], "reactionShape" : { "a" : { "x" : 606, "y" : 347 }, "b" : { "x" : 618, "y" : 359 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 612, "y" : 353 } }, "inputs" : [ { "id" : 27333, "points" : [ { "x" : 497, "y" : 364 } ] }, { "id" : 27325, "points" : [ { "x" : 487, "y" : 186 } ] } ], "outputs" : [ { "id" : 27334, "points" : [ { "x" : 689, "y" : 380 } ] }, { "id" : 27328, "points" : [ { "x" : 761, "y" : 182 }, { "x" : 735, "y" : 306 } ] }, { "id" : 27335, "points" : [ { "x" : 709, "y" : 360 } ] } ], "catalysts" : [ { "id" : 27336, "points" : [ { "x" : 612, "y" : 330 } ] } ] }, { "id" : 27462, "reactomeId" : 10337256, "displayName" : "cGMP binds CNG channel to form cGMP:CNG channel", "schemaClass" : "Reaction", "renderableClass" : "Reaction", "position" : { "x" : 2884, "y" : 115 }, "minX" : 2847, "maxX" : 2890, "minY" : 81, "maxY" : 121, "reactionType" : "binding", "segments" : [ { "from" : { "x" : 2886, "y" : 115 }, "to" : { "x" : 2884, "y" : 115 } }, { "from" : { "x" : 2884, "y" : 115 }, "to" : { "x" : 2847, "y" : 81 } } ], "endShape" : { "a" : { "x" : 2855, "y" : 83 }, "b" : { "x" : 2847, "y" : 81 }, "c" : { "x" : 2849, "y" : 89 }, "type" : "ARROW", "centre" : { "x" : 2849, "y" : 89 } }, "reactionShape" : { "c" : { "x" : 2884, "y" : 115 }, "r" : 5, "type" : "CIRCLE", "centre" : { "x" : 2884, "y" : 115 } }, "inputs" : [ { "id" : 27406, "points" : [ { "x" : 2995, "y" : 83 } ] }, { "id" : 27401, "points" : [ { "x" : 2649, "y" : 179 } ] } ], "outputs" : [ { "id" : 27405 } ] }, { "id" : 27463, "reactomeId" : 10392030, "displayName" : "CALM1:Ca2+ binds CNG channel", "schemaClass" : "Reaction", "renderableClass" : "Reaction", "position" : { "x" : 3095, "y" : 145 }, "minX" : 3068, "maxX" : 3101, "minY" : 118, "maxY" : 183, "reactionType" : "binding", "segments" : [ { "from" : { "x" : 3068, "y" : 118 }, "to" : { "x" : 3095, "y" : 145 } }, { "from" : { "x" : 3095, "y" : 145 }, "to" : { "x" : 3095, "y" : 183 } } ], "endShape" : { "a" : { "x" : 3091, "y" : 176 }, "b" : { "x" : 3095, "y" : 183 }, "c" : { "x" : 3099, "y" : 176 }, "type" : "ARROW", "centre" : { "x" : 3099, "y" : 176 } }, "reactionShape" : { "c" : { "x" : 3095, "y" : 145 }, "r" : 5, "type" : "CIRCLE", "centre" : { "x" : 3095, "y" : 145 } }, "inputs" : [ { "id" : 27406, "points" : [ { "x" : 3038, "y" : 83 } ] }, { "id" : 27464, "points" : [ { "x" : 3039, "y" : 118 } ] } ], "outputs" : [ { "id" : 27465 } ], "activators" : [ { "id" : 27411, "points" : [ { "x" : 2958, "y" : 173 } ] } ] }, { "id" : 27399, "reactomeId" : 10337282, "displayName" : "PDE6 hydrolyses cGMP to GMP", "schemaClass" : "Reaction", "renderableClass" : "Reaction", "position" : { "x" : 2117, "y" : 186 }, "minX" : 2111, "maxX" : 2300, "minY" : 180, "maxY" : 192, "reactionType" : "transition", "segments" : [ { "from" : { "x" : 2300, "y" : 186 }, "to" : { "x" : 2117, "y" : 186 } }, { "from" : { "x" : 2117, "y" : 186 }, "to" : { "x" : 2114, "y" : 186 } } ], "endShape" : { "a" : { "x" : 2121, "y" : 182 }, "b" : { "x" : 2114, "y" : 186 }, "c" : { "x" : 2121, "y" : 190 }, "type" : "ARROW", "centre" : { "x" : 2121, "y" : 190 } }, "reactionShape" : { "a" : { "x" : 2111, "y" : 180 }, "b" : { "x" : 2123, "y" : 192 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 2117, "y" : 186 } }, "inputs" : [ { "id" : 27400, "points" : [ { "x" : 2282, "y" : 206 } ] }, { "id" : 27401, "points" : [ { "x" : 2594, "y" : 186 } ] } ], "outputs" : [ { "id" : 27402 } ], "catalysts" : [ { "id" : 27403, "points" : [ { "x" : 2117, "y" : 284 } ] } ] }, { "id" : 27337, "reactomeId" : 10389262, "displayName" : "RBP3 transports 11cRAL to rod photoreceptor outer segment", "schemaClass" : "BlackBoxEvent", "renderableClass" : "Reaction", "position" : { "x" : 991, "y" : 206 }, "minX" : 940, "maxX" : 1055, "minY" : 200, "maxY" : 218, "reactionType" : "omitted", "segments" : [ { "from" : { "x" : 940, "y" : 206 }, "to" : { "x" : 991, "y" : 206 } }, { "from" : { "x" : 991, "y" : 206 }, "to" : { "x" : 1055, "y" : 218 } } ], "endShape" : { "a" : { "x" : 1047, "y" : 221 }, "b" : { "x" : 1055, "y" : 218 }, "c" : { "x" : 1049, "y" : 213 }, "type" : "ARROW", "centre" : { "x" : 1049, "y" : 213 } }, "reactionShape" : { "a" : { "x" : 985, "y" : 200 }, "b" : { "x" : 997, "y" : 212 }, "s" : "\\\\", "type" : "BOX", "empty" : true, "centre" : { "x" : 991, "y" : 206 } }, "inputs" : [ { "id" : 27338 } ], "outputs" : [ { "id" : 27339 } ], "catalysts" : [ { "id" : 27340, "points" : [ { "x" : 991, "y" : 161 } ] } ] }, { "id" : 27466, "reactomeId" : 10410933, "displayName" : "CYP4V2 omega-hydroxylates DHA to HDoHE", "schemaClass" : "Reaction", "renderableClass" : "Reaction", "position" : { "x" : 509, "y" : 572 }, "minX" : 463, "maxX" : 550, "minY" : 566, "maxY" : 578, "reactionType" : "transition", "segments" : [ { "from" : { "x" : 463, "y" : 572 }, "to" : { "x" : 509, "y" : 572 } }, { "from" : { "x" : 509, "y" : 572 }, "to" : { "x" : 550, "y" : 572 } } ], "reactionShape" : { "a" : { "x" : 503, "y" : 566 }, "b" : { "x" : 515, "y" : 578 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 509, "y" : 572 } }, "inputs" : [ { "id" : 27467, "points" : [ { "x" : 405, "y" : 572 } ] }, { "id" : 27468, "points" : [ { "x" : 414, "y" : 602 } ] }, { "id" : 27469, "points" : [ { "x" : 448, "y" : 600 } ] }, { "id" : 27470, "points" : [ { "x" : 451, "y" : 561 } ] } ], "outputs" : [ { "id" : 27471, "points" : [ { "x" : 592, "y" : 573 } ] }, { "id" : 27472, "points" : [ { "x" : 571, "y" : 555 } ] }, { "id" : 27473, "points" : [ { "x" : 574, "y" : 597 } ] } ], "catalysts" : [ { "id" : 27474, "points" : [ { "x" : 508, "y" : 531 } ] } ] }, { "id" : 27404, "reactomeId" : 10389731, "displayName" : "cGMP dissociates from CNG channels", "schemaClass" : "Reaction", "renderableClass" : "Reaction", "position" : { "x" : 2947, "y" : 66 }, "minX" : 2903, "maxX" : 2953, "minY" : 60, "maxY" : 72, "reactionType" : "dissociation", "segments" : [ { "from" : { "x" : 2903, "y" : 66 }, "to" : { "x" : 2947, "y" : 66 } }, { "from" : { "x" : 2947, "y" : 66 }, "to" : { "x" : 2948, "y" : 68 } } ], "reactionShape" : { "c" : { "x" : 2947, "y" : 66 }, "r" : 5, "r1" : 3, "type" : "DOUBLE_CIRCLE", "empty" : true, "centre" : { "x" : 2947, "y" : 66 } }, "inputs" : [ { "id" : 27405 } ], "outputs" : [ { "id" : 27406, "points" : [ { "x" : 2983, "y" : 68 } ] }, { "id" : 27401, "points" : [ { "x" : 2649, "y" : 177 } ] } ] }, { "id" : 27341, "reactomeId" : 10389264, "displayName" : "11cRAL binds to opsin to form 11c-retinyl:RHO", "schemaClass" : "Reaction", "renderableClass" : "Reaction", "position" : { "x" : 1145, "y" : 295 }, "minX" : 1127, "maxX" : 1163, "minY" : 289, "maxY" : 301, "reactionType" : "transition", "segments" : [ { "from" : { "x" : 1127, "y" : 295 }, "to" : { "x" : 1145, "y" : 295 } }, { "from" : { "x" : 1145, "y" : 295 }, "to" : { "x" : 1163, "y" : 295 } } ], "reactionShape" : { "a" : { "x" : 1139, "y" : 289 }, "b" : { "x" : 1151, "y" : 301 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 1145, "y" : 295 } }, "inputs" : [ { "id" : 27342, "points" : [ { "x" : 1113, "y" : 295 } ] }, { "id" : 27339, "points" : [ { "x" : 1096, "y" : 242 } ] } ], "outputs" : [ { "id" : 27343, "points" : [ { "x" : 1182, "y" : 295 } ] }, { "id" : 27344, "points" : [ { "x" : 1191, "y" : 325 } ] } ] }, { "id" : 27407, "reactomeId" : 10389734, "displayName" : "cGMP:CNG transports Na+ and Ca2+ into the rod outer segment", "schemaClass" : "Reaction", "renderableClass" : "Reaction", "position" : { "x" : 2745, "y" : 66 }, "minX" : 2739, "maxX" : 2751, "minY" : 60, "maxY" : 72, "reactionType" : "transition", "segments" : [ { "from" : { "x" : 2746, "y" : 66 }, "to" : { "x" : 2745, "y" : 66 } }, { "from" : { "x" : 2745, "y" : 66 }, "to" : { "x" : 2746, "y" : 68 } } ], "reactionShape" : { "a" : { "x" : 2739, "y" : 60 }, "b" : { "x" : 2751, "y" : 72 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 2745, "y" : 66 } }, "inputs" : [ { "id" : 27408, "points" : [ { "x" : 2720, "y" : 34 } ] }, { "id" : 27409, "points" : [ { "x" : 2770, "y" : 34 } ] } ], "outputs" : [ { "id" : 27410, "points" : [ { "x" : 2696, "y" : 92 } ] }, { "id" : 27411, "points" : [ { "x" : 2905, "y" : 161 } ] } ], "catalysts" : [ { "id" : 27405, "points" : [ { "x" : 2770, "y" : 66 } ] } ] }, { "id" : 27345, "reactomeId" : 10377796, "displayName" : "ABCA4 mediates atRAL transport", "schemaClass" : "Reaction", "renderableClass" : "Reaction", "position" : { "x" : 1648, "y" : 477 }, "minX" : 1642, "maxX" : 1674, "minY" : 471, "maxY" : 532, "reactionType" : "transition", "segments" : [ { "from" : { "x" : 1674, "y" : 477 }, "to" : { "x" : 1648, "y" : 477 } }, { "from" : { "x" : 1648, "y" : 477 }, "to" : { "x" : 1668, "y" : 532 } } ], "reactionShape" : { "a" : { "x" : 1642, "y" : 471 }, "b" : { "x" : 1654, "y" : 483 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 1648, "y" : 477 } }, "inputs" : [ { "id" : 27346, "points" : [ { "x" : 1703, "y" : 431 } ] }, { "id" : 27347, "points" : [ { "x" : 1693, "y" : 472 } ] }, { "id" : 27348, "points" : [ { "x" : 1695, "y" : 492 } ] } ], "outputs" : [ { "id" : 27349, "points" : [ { "x" : 1652, "y" : 553 } ] }, { "id" : 27350, "points" : [ { "x" : 1683, "y" : 564 } ] }, { "id" : 27351, "points" : [ { "x" : 1747, "y" : 577 } ] } ], "catalysts" : [ { "id" : 27352, "points" : [ { "x" : 1648, "y" : 425 } ] } ] }, { "id" : 27475, "reactomeId" : 10410926, "displayName" : "KAMKMT transfers 3xCH3 groups from 3xAdoMet to CALM1", "schemaClass" : "Reaction", "renderableClass" : "Reaction", "position" : { "x" : 2897, "y" : 550 }, "minX" : 2852, "maxX" : 2952, "minY" : 544, "maxY" : 556, "reactionType" : "transition", "segments" : [ { "from" : { "x" : 2952, "y" : 550 }, "to" : { "x" : 2897, "y" : 550 } }, { "from" : { "x" : 2897, "y" : 550 }, "to" : { "x" : 2852, "y" : 550 } } ], "reactionShape" : { "a" : { "x" : 2891, "y" : 544 }, "b" : { "x" : 2903, "y" : 556 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 2897, "y" : 550 } }, "inputs" : [ { "id" : 27476, "points" : [ { "x" : 2972, "y" : 542 } ] }, { "id" : 27477, "points" : [ { "x" : 2974, "y" : 578 } ], "stoichiometry" : 3 } ], "outputs" : [ { "id" : 27478, "points" : [ { "x" : 2830, "y" : 593 } ], "stoichiometry" : 3 }, { "id" : 27479, "points" : [ { "x" : 2819, "y" : 550 } ] } ], "catalysts" : [ { "id" : 27480, "points" : [ { "x" : 2897, "y" : 507 } ] } ] }, { "id" : 27412, "reactomeId" : 10389826, "displayName" : "METAP1/2 demethylates GNAT1", "schemaClass" : "Reaction", "renderableClass" : "Reaction", "position" : { "x" : 1148, "y" : 574 }, "minX" : 1105, "maxX" : 1186, "minY" : 568, "maxY" : 580, "reactionType" : "transition", "segments" : [ { "from" : { "x" : 1105, "y" : 574 }, "to" : { "x" : 1148, "y" : 574 } }, { "from" : { "x" : 1148, "y" : 574 }, "to" : { "x" : 1186, "y" : 574 } } ], "reactionShape" : { "a" : { "x" : 1142, "y" : 568 }, "b" : { "x" : 1154, "y" : 580 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 1148, "y" : 574 } }, "inputs" : [ { "id" : 27413 } ], "outputs" : [ { "id" : 27414, "points" : [ { "x" : 1215, "y" : 592 } ] }, { "id" : 27415, "points" : [ { "x" : 1245, "y" : 547 } ] } ], "catalysts" : [ { "id" : 27416, "points" : [ { "x" : 1147, "y" : 600 } ] } ] }, { "id" : 27481, "reactomeId" : 10428628, "displayName" : "RLBP1:11cRAL dissociates", "schemaClass" : "Reaction", "renderableClass" : "Reaction", "position" : { "x" : 838, "y" : 208 }, "minX" : 784, "maxX" : 844, "minY" : 182, "maxY" : 214, "reactionType" : "dissociation", "segments" : [ { "from" : { "x" : 784, "y" : 182 }, "to" : { "x" : 838, "y" : 208 } }, { "from" : { "x" : 838, "y" : 208 }, "to" : { "x" : 836, "y" : 206 } } ], "reactionShape" : { "c" : { "x" : 838, "y" : 208 }, "r" : 5, "r1" : 3, "type" : "DOUBLE_CIRCLE", "empty" : true, "centre" : { "x" : 838, "y" : 208 } }, "inputs" : [ { "id" : 27328 } ], "outputs" : [ { "id" : 27338, "points" : [ { "x" : 873, "y" : 206 } ] }, { "id" : 27324, "points" : [ { "x" : 352, "y" : 118 }, { "x" : 352, "y" : 75 }, { "x" : 806, "y" : 75 } ] } ] }, { "id" : 27353, "reactomeId" : 10389328, "displayName" : "RDH12 reduces atRAL to atROL", "schemaClass" : "Reaction", "renderableClass" : "Reaction", "position" : { "x" : 1908, "y" : 712 }, "minX" : 1888, "maxX" : 1918, "minY" : 645, "maxY" : 749, "reactionType" : "transition", "segments" : [ { "from" : { "x" : 1888, "y" : 645 }, "to" : { "x" : 1908, "y" : 712 } }, { "from" : { "x" : 1908, "y" : 712 }, "to" : { "x" : 1918, "y" : 749 } } ], "reactionShape" : { "a" : { "x" : 1902, "y" : 706 }, "b" : { "x" : 1914, "y" : 718 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 1908, "y" : 712 } }, "inputs" : [ { "id" : 27354, "points" : [ { "x" : 1868, "y" : 702 } ] }, { "id" : 27355, "points" : [ { "x" : 1863, "y" : 657 } ] }, { "id" : 27351, "points" : [ { "x" : 1803, "y" : 603 } ] } ], "outputs" : [ { "id" : 27356, "points" : [ { "x" : 1887, "y" : 796 } ] }, { "id" : 27357, "points" : [ { "x" : 1901, "y" : 757 } ] } ], "catalysts" : [ { "id" : 27358, "points" : [ { "x" : 2168, "y" : 832 } ] } ] }, { "id" : 27417, "reactomeId" : 10389807, "displayName" : "NMT1/2 transfer MYS to GNAT1", "schemaClass" : "Reaction", "renderableClass" : "Reaction", "position" : { "x" : 1361, "y" : 486 }, "minX" : 1330, "maxX" : 1399, "minY" : 480, "maxY" : 495, "reactionType" : "transition", "segments" : [ { "from" : { "x" : 1330, "y" : 495 }, "to" : { "x" : 1361, "y" : 486 } }, { "from" : { "x" : 1361, "y" : 486 }, "to" : { "x" : 1399, "y" : 486 } } ], "reactionShape" : { "a" : { "x" : 1355, "y" : 480 }, "b" : { "x" : 1367, "y" : 492 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 1361, "y" : 486 } }, "inputs" : [ { "id" : 27418, "points" : [ { "x" : 1293, "y" : 479 } ] }, { "id" : 27415, "points" : [ { "x" : 1309, "y" : 505 } ] } ], "outputs" : [ { "id" : 27419, "points" : [ { "x" : 1405, "y" : 420 } ] }, { "id" : 27420, "points" : [ { "x" : 1448, "y" : 471 } ] } ], "catalysts" : [ { "id" : 27421, "points" : [ { "x" : 1361, "y" : 462 } ] } ] }, { "id" : 27482, "reactomeId" : 10433492, "displayName" : "OPN1SW binds 11cRAL", "schemaClass" : "Reaction", "renderableClass" : "Reaction", "position" : { "x" : 1466, "y" : 1305 }, "minX" : 1445, "maxX" : 1479, "minY" : 1285, "maxY" : 1311, "reactionType" : "transition", "segments" : [ { "from" : { "x" : 1445, "y" : 1297 }, "to" : { "x" : 1466, "y" : 1305 } }, { "from" : { "x" : 1466, "y" : 1305 }, "to" : { "x" : 1479, "y" : 1285 } } ], "reactionShape" : { "a" : { "x" : 1460, "y" : 1299 }, "b" : { "x" : 1472, "y" : 1311 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 1466, "y" : 1305 } }, "inputs" : [ { "id" : 27483, "points" : [ { "x" : 1492, "y" : 1202 } ] }, { "id" : 27379, "points" : [ { "x" : 1306, "y" : 1277 } ] } ], "outputs" : [ { "id" : 27484, "points" : [ { "x" : 1572, "y" : 1295 } ] }, { "id" : 27381, "points" : [ { "x" : 1499, "y" : 1301 } ] } ] }, { "id" : 27485, "reactomeId" : 10433494, "displayName" : "OPN1MW binds 11cRAL", "schemaClass" : "Reaction", "renderableClass" : "Reaction", "position" : { "x" : 1456, "y" : 1243 }, "minX" : 1385, "maxX" : 1510, "minY" : 1237, "maxY" : 1259, "reactionType" : "transition", "segments" : [ { "from" : { "x" : 1385, "y" : 1259 }, "to" : { "x" : 1456, "y" : 1243 } }, { "from" : { "x" : 1456, "y" : 1243 }, "to" : { "x" : 1510, "y" : 1258 } } ], "reactionShape" : { "a" : { "x" : 1450, "y" : 1237 }, "b" : { "x" : 1462, "y" : 1249 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 1456, "y" : 1243 } }, "inputs" : [ { "id" : 27486, "points" : [ { "x" : 1342, "y" : 1244 } ] }, { "id" : 27379, "points" : [ { "x" : 1306, "y" : 1269 } ] } ], "outputs" : [ { "id" : 27487, "points" : [ { "x" : 1579, "y" : 1245 } ] }, { "id" : 27381, "points" : [ { "x" : 1513, "y" : 1301 } ] } ] }, { "id" : 27422, "reactomeId" : 10389793, "displayName" : "FNTA:FNTB transfers FARN to GNGT1", "schemaClass" : "Reaction", "renderableClass" : "Reaction", "position" : { "x" : 1127, "y" : 439 }, "minX" : 1101, "maxX" : 1155, "minY" : 433, "maxY" : 445, "reactionType" : "transition", "segments" : [ { "from" : { "x" : 1101, "y" : 439 }, "to" : { "x" : 1127, "y" : 439 } }, { "from" : { "x" : 1127, "y" : 439 }, "to" : { "x" : 1155, "y" : 439 } } ], "reactionShape" : { "a" : { "x" : 1121, "y" : 433 }, "b" : { "x" : 1133, "y" : 445 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 1127, "y" : 439 } }, "inputs" : [ { "id" : 27423, "points" : [ { "x" : 1084, "y" : 420 } ] }, { "id" : 27424, "points" : [ { "x" : 1089, "y" : 446 } ] } ], "outputs" : [ { "id" : 27425, "points" : [ { "x" : 1187, "y" : 421 } ] }, { "id" : 27426, "points" : [ { "x" : 1172, "y" : 457 } ] } ], "catalysts" : [ { "id" : 27427, "points" : [ { "x" : 1126, "y" : 493 } ] } ] }, { "id" : 27359, "reactomeId" : 10389321, "displayName" : "RBP3 regulates the transport of atROL from ROS to RPE", "schemaClass" : "BlackBoxEvent", "renderableClass" : "Reaction", "position" : { "x" : 991, "y" : 795 }, "minX" : 529, "maxX" : 1876, "minY" : 739, "maxY" : 976, "reactionType" : "omitted", "segments" : [ { "from" : { "x" : 1876, "y" : 832 }, "to" : { "x" : 1865, "y" : 976 } }, { "from" : { "x" : 1865, "y" : 976 }, "to" : { "x" : 991, "y" : 976 } }, { "from" : { "x" : 991, "y" : 976 }, "to" : { "x" : 991, "y" : 795 } }, { "from" : { "x" : 991, "y" : 795 }, "to" : { "x" : 925, "y" : 739 } }, { "from" : { "x" : 925, "y" : 739 }, "to" : { "x" : 529, "y" : 739 } } ], "endShape" : { "a" : { "x" : 536, "y" : 735 }, "b" : { "x" : 529, "y" : 739 }, "c" : { "x" : 536, "y" : 743 }, "type" : "ARROW", "centre" : { "x" : 536, "y" : 743 } }, "reactionShape" : { "a" : { "x" : 985, "y" : 789 }, "b" : { "x" : 997, "y" : 801 }, "s" : "\\\\", "type" : "BOX", "empty" : true, "centre" : { "x" : 991, "y" : 795 } }, "inputs" : [ { "id" : 27356 } ], "outputs" : [ { "id" : 27307 } ], "catalysts" : [ { "id" : 27360, "points" : [ { "x" : 992, "y" : 774 } ] } ] }, { "id" : 27488, "reactomeId" : 10337291, "displayName" : "Photons induce isomerization of 11c-retinyl to at-retinyl", "schemaClass" : "Reaction", "renderableClass" : "Reaction", "position" : { "x" : 1315, "y" : 296 }, "minX" : 1304, "maxX" : 1326, "minY" : 290, "maxY" : 302, "reactionType" : "transition", "segments" : [ { "from" : { "x" : 1304, "y" : 296 }, "to" : { "x" : 1315, "y" : 296 } }, { "from" : { "x" : 1315, "y" : 296 }, "to" : { "x" : 1326, "y" : 295 } } ], "endShape" : { "a" : { "x" : 1319, "y" : 300 }, "b" : { "x" : 1326, "y" : 295 }, "c" : { "x" : 1319, "y" : 292 }, "type" : "ARROW", "centre" : { "x" : 1319, "y" : 292 } }, "reactionShape" : { "a" : { "x" : 1309, "y" : 290 }, "b" : { "x" : 1321, "y" : 302 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 1315, "y" : 296 } }, "inputs" : [ { "id" : 27343, "points" : [ { "x" : 1294, "y" : 296 } ] }, { "id" : 27489, "points" : [ { "x" : 1303, "y" : 36 } ] } ], "outputs" : [ { "id" : 27430 } ] }, { "id" : 27361, "reactomeId" : 10389373, "displayName" : "RBP3 regulates atROL taken up by Muller cells", "schemaClass" : "BlackBoxEvent", "renderableClass" : "Reaction", "position" : { "x" : 923, "y" : 1036 }, "minX" : 843, "maxX" : 1267, "minY" : 1030, "maxY" : 1042, "reactionType" : "omitted", "segments" : [ { "from" : { "x" : 1267, "y" : 1036 }, "to" : { "x" : 923, "y" : 1036 } }, { "from" : { "x" : 923, "y" : 1036 }, "to" : { "x" : 843, "y" : 1036 } } ], "endShape" : { "a" : { "x" : 850, "y" : 1032 }, "b" : { "x" : 843, "y" : 1036 }, "c" : { "x" : 850, "y" : 1040 }, "type" : "ARROW", "centre" : { "x" : 850, "y" : 1040 } }, "reactionShape" : { "a" : { "x" : 917, "y" : 1030 }, "b" : { "x" : 929, "y" : 1042 }, "s" : "\\\\", "type" : "BOX", "empty" : true, "centre" : { "x" : 923, "y" : 1036 } }, "inputs" : [ { "id" : 27362 } ], "outputs" : [ { "id" : 27363 } ], "catalysts" : [ { "id" : 27364, "points" : [ { "x" : 921, "y" : 1130 } ] } ] }, { "id" : 27428, "reactomeId" : 10390072, "displayName" : "GRK1,4,7 phosphorylate MII to p-MII", "schemaClass" : "Reaction", "renderableClass" : "Reaction", "position" : { "x" : 1872, "y" : 407 }, "minX" : 1825, "maxX" : 1906, "minY" : 401, "maxY" : 413, "reactionType" : "transition", "segments" : [ { "from" : { "x" : 1825, "y" : 407 }, "to" : { "x" : 1872, "y" : 407 } }, { "from" : { "x" : 1872, "y" : 407 }, "to" : { "x" : 1906, "y" : 407 } } ], "reactionShape" : { "a" : { "x" : 1866, "y" : 401 }, "b" : { "x" : 1878, "y" : 413 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 1872, "y" : 407 } }, "inputs" : [ { "id" : 27429, "points" : [ { "x" : 1801, "y" : 422 } ], "stoichiometry" : 3 }, { "id" : 27430, "points" : [ { "x" : 1394, "y" : 309 }, { "x" : 1445, "y" : 336 } ] } ], "outputs" : [ { "id" : 27431, "points" : [ { "x" : 1940, "y" : 437 } ], "stoichiometry" : 3 }, { "id" : 27432, "points" : [ { "x" : 1950, "y" : 408 } ] } ], "catalysts" : [ { "id" : 27433, "points" : [ { "x" : 1857, "y" : 346 } ] } ], "inhibitors" : [ { "id" : 27434, "points" : [ { "x" : 1844, "y" : 431 } ] }, { "id" : 27435, "points" : [ { "x" : 2175, "y" : 422 }, { "x" : 2122, "y" : 490 }, { "x" : 1946, "y" : 490 } ] }, { "id" : 27436, "points" : [ { "x" : 1973, "y" : 558 } ] } ] }, { "id" : 27365, "reactomeId" : 10389384, "displayName" : "RLBP1 binds atROL to form RLBP1:atROL", "schemaClass" : "Reaction", "renderableClass" : "Reaction", "position" : { "x" : 733, "y" : 1036 }, "minX" : 703, "maxX" : 759, "minY" : 1030, "maxY" : 1042, "reactionType" : "binding", "segments" : [ { "from" : { "x" : 759, "y" : 1035 }, "to" : { "x" : 733, "y" : 1036 } }, { "from" : { "x" : 733, "y" : 1036 }, "to" : { "x" : 703, "y" : 1036 } } ], "endShape" : { "a" : { "x" : 710, "y" : 1032 }, "b" : { "x" : 703, "y" : 1036 }, "c" : { "x" : 710, "y" : 1040 }, "type" : "ARROW", "centre" : { "x" : 710, "y" : 1040 } }, "reactionShape" : { "c" : { "x" : 733, "y" : 1036 }, "r" : 5, "type" : "CIRCLE", "centre" : { "x" : 733, "y" : 1036 } }, "inputs" : [ { "id" : 27363, "points" : [ { "x" : 786, "y" : 1035 } ] }, { "id" : 27366, "points" : [ { "x" : 773, "y" : 1066 } ] } ], "outputs" : [ { "id" : 27367 } ] }, { "id" : 27301, "reactomeId" : 10389230, "displayName" : "TTR:RBP:atROL binds to STRA6 receptor", "schemaClass" : "Reaction", "renderableClass" : "Reaction", "position" : { "x" : 299, "y" : 806 }, "minX" : 269, "maxX" : 324, "minY" : 800, "maxY" : 812, "reactionType" : "binding", "segments" : [ { "from" : { "x" : 275, "y" : 806 }, "to" : { "x" : 299, "y" : 806 } }, { "from" : { "x" : 299, "y" : 806 }, "to" : { "x" : 324, "y" : 806 } } ], "endShape" : { "a" : { "x" : 317, "y" : 810 }, "b" : { "x" : 324, "y" : 806 }, "c" : { "x" : 317, "y" : 802 }, "type" : "ARROW", "centre" : { "x" : 317, "y" : 802 } }, "reactionShape" : { "c" : { "x" : 299, "y" : 806 }, "r" : 5, "type" : "CIRCLE", "centre" : { "x" : 299, "y" : 806 } }, "inputs" : [ { "id" : 27302, "points" : [ { "x" : 230, "y" : 858 } ] }, { "id" : 27303, "points" : [ { "x" : 235, "y" : 785 } ] } ], "outputs" : [ { "id" : 27304 } ] }, { "id" : 27368, "reactomeId" : 10389367, "displayName" : "AWAT2 transfers PALM to 11cROL forming 11cRPALM", "schemaClass" : "Reaction", "renderableClass" : "Reaction", "position" : { "x" : 383, "y" : 1105 }, "minX" : 377, "maxX" : 389, "minY" : 1076, "maxY" : 1139, "reactionType" : "transition", "segments" : [ { "from" : { "x" : 383, "y" : 1076 }, "to" : { "x" : 383, "y" : 1105 } }, { "from" : { "x" : 383, "y" : 1105 }, "to" : { "x" : 383, "y" : 1139 } } ], "reactionShape" : { "a" : { "x" : 377, "y" : 1099 }, "b" : { "x" : 389, "y" : 1111 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 383, "y" : 1105 } }, "inputs" : [ { "id" : 27369, "points" : [ { "x" : 354, "y" : 1072 } ] }, { "id" : 27370, "points" : [ { "x" : 383, "y" : 1049 } ] } ], "outputs" : [ { "id" : 27371, "points" : [ { "x" : 359, "y" : 1143 } ] }, { "id" : 27372, "points" : [ { "x" : 383, "y" : 1177 } ] } ], "catalysts" : [ { "id" : 27373, "points" : [ { "x" : 419, "y" : 1105 } ] } ] }, { "id" : 27305, "reactomeId" : 10389228, "displayName" : "STRA6 transports atROL from extracellular region to cytosol", "schemaClass" : "Reaction", "renderableClass" : "Reaction", "position" : { "x" : 473, "y" : 806 }, "minX" : 439, "maxX" : 499, "minY" : 800, "maxY" : 812, "reactionType" : "dissociation", "segments" : [ { "from" : { "x" : 439, "y" : 806 }, "to" : { "x" : 473, "y" : 806 } }, { "from" : { "x" : 473, "y" : 806 }, "to" : { "x" : 499, "y" : 806 } } ], "reactionShape" : { "c" : { "x" : 473, "y" : 806 }, "r" : 5, "r1" : 3, "type" : "DOUBLE_CIRCLE", "empty" : true, "centre" : { "x" : 473, "y" : 806 } }, "inputs" : [ { "id" : 27304 } ], "outputs" : [ { "id" : 27306, "points" : [ { "x" : 525, "y" : 806 } ] }, { "id" : 27307, "points" : [ { "x" : 499, "y" : 757 } ] } ] }, { "id" : 27308, "reactomeId" : 10337753, "displayName" : "atROL binds RBP1 to form RBP1:atROL", "schemaClass" : "Reaction", "renderableClass" : "Reaction", "position" : { "x" : 396, "y" : 739 }, "minX" : 364, "maxX" : 402, "minY" : 733, "maxY" : 745, "reactionType" : "binding", "segments" : [ { "from" : { "x" : 397, "y" : 739 }, "to" : { "x" : 396, "y" : 739 } }, { "from" : { "x" : 396, "y" : 739 }, "to" : { "x" : 364, "y" : 739 } } ], "endShape" : { "a" : { "x" : 371, "y" : 735 }, "b" : { "x" : 364, "y" : 739 }, "c" : { "x" : 371, "y" : 743 }, "type" : "ARROW", "centre" : { "x" : 371, "y" : 743 } }, "reactionShape" : { "c" : { "x" : 396, "y" : 739 }, "r" : 5, "type" : "CIRCLE", "centre" : { "x" : 396, "y" : 739 } }, "inputs" : [ { "id" : 27307, "points" : [ { "x" : 472, "y" : 739 } ] }, { "id" : 27309, "points" : [ { "x" : 419, "y" : 717 } ] } ], "outputs" : [ { "id" : 27310 } ] }, { "id" : 27437, "reactomeId" : 10390098, "displayName" : "at-retinyl is hydrolysed from p-MII:SAG to release atRAL", "schemaClass" : "Reaction", "renderableClass" : "Reaction", "position" : { "x" : 2244, "y" : 407 }, "minX" : 2238, "maxX" : 2257, "minY" : 401, "maxY" : 413, "reactionType" : "transition", "segments" : [ { "from" : { "x" : 2238, "y" : 407 }, "to" : { "x" : 2244, "y" : 407 } }, { "from" : { "x" : 2244, "y" : 407 }, "to" : { "x" : 2251, "y" : 407 } } ], "reactionShape" : { "a" : { "x" : 2238, "y" : 401 }, "b" : { "x" : 2250, "y" : 413 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 2244, "y" : 407 } }, "inputs" : [ { "id" : 27438, "points" : [ { "x" : 2220, "y" : 424 } ] }, { "id" : 27435, "points" : [ { "x" : 2224, "y" : 405 } ] } ], "outputs" : [ { "id" : 27346, "points" : [ { "x" : 1731, "y" : 431 }, { "x" : 1843, "y" : 516 }, { "x" : 2232, "y" : 520 } ] }, { "id" : 27439, "points" : [ { "x" : 2283, "y" : 407 } ] } ] }, { "id" : 27374, "reactomeId" : 10389371, "displayName" : "11cROL translocates from Muller cells to cone photoreceptor cells", "schemaClass" : "BlackBoxEvent", "renderableClass" : "Reaction", "position" : { "x" : 923, "y" : 1257 }, "minX" : 808, "maxX" : 1004, "minY" : 1251, "maxY" : 1269, "reactionType" : "omitted", "segments" : [ { "from" : { "x" : 808, "y" : 1257 }, "to" : { "x" : 923, "y" : 1257 } }, { "from" : { "x" : 923, "y" : 1257 }, "to" : { "x" : 1004, "y" : 1269 } } ], "endShape" : { "a" : { "x" : 997, "y" : 1272 }, "b" : { "x" : 1004, "y" : 1269 }, "c" : { "x" : 998, "y" : 1264 }, "type" : "ARROW", "centre" : { "x" : 998, "y" : 1264 } }, "reactionShape" : { "a" : { "x" : 917, "y" : 1251 }, "b" : { "x" : 929, "y" : 1263 }, "s" : "\\\\", "type" : "BOX", "empty" : true, "centre" : { "x" : 923, "y" : 1257 } }, "inputs" : [ { "id" : 27375 } ], "outputs" : [ { "id" : 27376 } ], "catalysts" : [ { "id" : 27364, "points" : [ { "x" : 921, "y" : 1158 } ] } ] }, { "id" : 27311, "reactomeId" : 10389218, "displayName" : "LRAT esterifies RBP1:atROL and FACYLs to atREs", "schemaClass" : "Reaction", "renderableClass" : "Reaction", "position" : { "x" : 317, "y" : 534 }, "minX" : 302, "maxX" : 323, "minY" : 474, "maxY" : 627, "reactionType" : "transition", "segments" : [ { "from" : { "x" : 318, "y" : 627 }, "to" : { "x" : 317, "y" : 534 } }, { "from" : { "x" : 317, "y" : 534 }, "to" : { "x" : 302, "y" : 474 } } ], "reactionShape" : { "a" : { "x" : 311, "y" : 528 }, "b" : { "x" : 323, "y" : 540 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 317, "y" : 534 } }, "inputs" : [ { "id" : 27312, "points" : [ { "x" : 255, "y" : 620 } ] }, { "id" : 27310, "points" : [ { "x" : 319, "y" : 725 } ] } ], "outputs" : [ { "id" : 27313, "points" : [ { "x" : 285, "y" : 412 } ] }, { "id" : 27314, "points" : [ { "x" : 271, "y" : 491 } ] } ], "catalysts" : [ { "id" : 27315, "points" : [ { "x" : 367, "y" : 519 } ] } ] }, { "id" : 27440, "reactomeId" : 10337831, "displayName" : "PP2A dephosphorylates p-RHO to RHO", "schemaClass" : "Reaction", "renderableClass" : "Reaction", "position" : { "x" : 2639, "y" : 408 }, "minX" : 2609, "maxX" : 2680, "minY" : 402, "maxY" : 414, "reactionType" : "transition", "segments" : [ { "from" : { "x" : 2609, "y" : 408 }, "to" : { "x" : 2639, "y" : 408 } }, { "from" : { "x" : 2639, "y" : 408 }, "to" : { "x" : 2680, "y" : 408 } } ], "reactionShape" : { "a" : { "x" : 2633, "y" : 402 }, "b" : { "x" : 2645, "y" : 414 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 2639, "y" : 408 } }, "inputs" : [ { "id" : 27441, "points" : [ { "x" : 2568, "y" : 407 } ] }, { "id" : 27442, "points" : [ { "x" : 2576, "y" : 439 } ], "stoichiometry" : 3 } ], "outputs" : [ { "id" : 27342, "points" : [ { "x" : 1096, "y" : 310 }, { "x" : 1122, "y" : 373 }, { "x" : 2657, "y" : 375 } ] }, { "id" : 27443, "points" : [ { "x" : 2728, "y" : 439 } ], "stoichiometry" : 3 } ], "catalysts" : [ { "id" : 27444, "points" : [ { "x" : 2639, "y" : 509 } ] } ], "inhibitors" : [ { "id" : 27435, "points" : [ { "x" : 2185, "y" : 422 }, { "x" : 2175, "y" : 493 }, { "x" : 2562, "y" : 493 } ] } ], "activators" : [ { "id" : 27445, "points" : [ { "x" : 2693, "y" : 462 } ] } ] }, { "id" : 27377, "reactomeId" : 10389369, "displayName" : "OPN1LW binds 11cRAL", "schemaClass" : "Reaction", "renderableClass" : "Reaction", "position" : { "x" : 1397, "y" : 1273 }, "minX" : 1391, "maxX" : 1496, "minY" : 1267, "maxY" : 1279, "reactionType" : "transition", "segments" : [ { "from" : { "x" : 1397, "y" : 1273 }, "to" : { "x" : 1447, "y" : 1273 } }, { "from" : { "x" : 1447, "y" : 1273 }, "to" : { "x" : 1496, "y" : 1273 } } ], "reactionShape" : { "a" : { "x" : 1391, "y" : 1267 }, "b" : { "x" : 1403, "y" : 1279 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 1397, "y" : 1273 } }, "inputs" : [ { "id" : 27378, "points" : [ { "x" : 1413, "y" : 1232 } ] }, { "id" : 27379, "points" : [ { "x" : 1306, "y" : 1273 } ] } ], "outputs" : [ { "id" : 27380, "points" : [ { "x" : 1572, "y" : 1268 } ] }, { "id" : 27381, "points" : [ { "x" : 1508, "y" : 1301 } ] } ] }, { "id" : 27316, "reactomeId" : 10389215, "displayName" : "RPE65 isomero-hydrolyses atREs to 11cROL", "schemaClass" : "Reaction", "renderableClass" : "Reaction", "position" : { "x" : 287, "y" : 288 }, "minX" : 281, "maxX" : 302, "minY" : 249, "maxY" : 345, "reactionType" : "transition", "segments" : [ { "from" : { "x" : 288, "y" : 345 }, "to" : { "x" : 287, "y" : 288 } }, { "from" : { "x" : 287, "y" : 288 }, "to" : { "x" : 302, "y" : 249 } } ], "reactionShape" : { "a" : { "x" : 281, "y" : 282 }, "b" : { "x" : 293, "y" : 294 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 287, "y" : 288 } }, "inputs" : [ { "id" : 27317, "points" : [ { "x" : 388, "y" : 364 } ] }, { "id" : 27313, "points" : [ { "x" : 283, "y" : 375 } ] } ], "outputs" : [ { "id" : 27318, "points" : [ { "x" : 320, "y" : 205 } ] }, { "id" : 27319, "points" : [ { "x" : 328, "y" : 313 } ] }, { "id" : 27320, "points" : [ { "x" : 330, "y" : 238 } ] } ], "catalysts" : [ { "id" : 27321, "points" : [ { "x" : 240, "y" : 288 } ] } ], "activators" : [ { "id" : 27322, "points" : [ { "x" : 261, "y" : 238 } ] } ] }, { "id" : 27446, "reactomeId" : 10390089, "displayName" : "GNAT1-GTP hydrolyses its bound GTP to GDP", "schemaClass" : "Reaction", "renderableClass" : "Reaction", "position" : { "x" : 2258, "y" : 296 }, "minX" : 2030, "maxX" : 2264, "minY" : 253, "maxY" : 302, "reactionType" : "transition", "segments" : [ { "from" : { "x" : 2222, "y" : 296 }, "to" : { "x" : 2258, "y" : 296 } }, { "from" : { "x" : 2258, "y" : 296 }, "to" : { "x" : 2233, "y" : 253 } }, { "from" : { "x" : 2233, "y" : 253 }, "to" : { "x" : 2030, "y" : 253 } } ], "reactionShape" : { "a" : { "x" : 2252, "y" : 290 }, "b" : { "x" : 2264, "y" : 302 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 2258, "y" : 296 } }, "inputs" : [ { "id" : 27400, "points" : [ { "x" : 2260, "y" : 242 } ] }, { "id" : 27403, "points" : [ { "x" : 2180, "y" : 296 } ] } ], "outputs" : [ { "id" : 27447, "points" : [ { "x" : 2004, "y" : 233 } ] }, { "id" : 27448, "points" : [ { "x" : 1946, "y" : 284 } ] }, { "id" : 27449, "points" : [ { "x" : 2007, "y" : 281 } ] } ], "catalysts" : [ { "id" : 27403, "points" : [ { "x" : 2175, "y" : 312 }, { "x" : 2259, "y" : 325 } ] } ], "activators" : [ { "id" : 27450, "points" : [ { "x" : 2288, "y" : 296 } ] } ] }, { "id" : 27382, "reactomeId" : 10389358, "displayName" : "Photons induce isomerisation of 11c-retinyl to at-retinyl", "schemaClass" : "Reaction", "renderableClass" : "Reaction", "position" : { "x" : 1932, "y" : 1210 }, "minX" : 1926, "maxX" : 1938, "minY" : 1149, "maxY" : 1260, "reactionType" : "transition", "segments" : [ { "from" : { "x" : 1932, "y" : 1260 }, "to" : { "x" : 1932, "y" : 1210 } }, { "from" : { "x" : 1932, "y" : 1210 }, "to" : { "x" : 1930, "y" : 1149 } } ], "endShape" : { "a" : { "x" : 1934, "y" : 1156 }, "b" : { "x" : 1930, "y" : 1149 }, "c" : { "x" : 1926, "y" : 1156 }, "type" : "ARROW", "centre" : { "x" : 1926, "y" : 1156 } }, "reactionShape" : { "a" : { "x" : 1926, "y" : 1204 }, "b" : { "x" : 1938, "y" : 1216 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 1932, "y" : 1210 } }, "inputs" : [ { "id" : 27383, "points" : [ { "x" : 1869, "y" : 1260 } ] }, { "id" : 27384, "points" : [ { "x" : 1874, "y" : 1364 } ] } ], "outputs" : [ { "id" : 27385 } ] }, { "id" : 27386, "reactomeId" : 10389426, "displayName" : "at-retinyl is hydrolysed from R* to release atRAL", "schemaClass" : "Reaction", "renderableClass" : "Reaction", "position" : { "x" : 1664, "y" : 1111 }, "minX" : 1600, "maxX" : 1696, "minY" : 1105, "maxY" : 1117, "reactionType" : "transition", "segments" : [ { "from" : { "x" : 1696, "y" : 1111 }, "to" : { "x" : 1664, "y" : 1111 } }, { "from" : { "x" : 1664, "y" : 1111 }, "to" : { "x" : 1600, "y" : 1111 } } ], "reactionShape" : { "a" : { "x" : 1658, "y" : 1105 }, "b" : { "x" : 1670, "y" : 1117 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 1664, "y" : 1111 } }, "inputs" : [ { "id" : 27385, "points" : [ { "x" : 1873, "y" : 1121 } ] }, { "id" : 27387, "points" : [ { "x" : 1732, "y" : 1089 } ] } ], "outputs" : [ { "id" : 27388, "points" : [ { "x" : 1458, "y" : 1139 } ] }, { "id" : 27389, "points" : [ { "x" : 1562, "y" : 1071 } ] } ] }, { "id" : 27451, "reactomeId" : 10390094, "displayName" : "GUCA binds Ca2+ to form GUCA:Ca2+", "schemaClass" : "Reaction", "renderableClass" : "Reaction", "position" : { "x" : 2871, "y" : 241 }, "minX" : 2813, "maxX" : 2877, "minY" : 235, "maxY" : 277, "reactionType" : "transition", "segments" : [ { "from" : { "x" : 2871, "y" : 243 }, "to" : { "x" : 2870, "y" : 243 } }, { "from" : { "x" : 2870, "y" : 243 }, "to" : { "x" : 2871, "y" : 241 } }, { "from" : { "x" : 2871, "y" : 241 }, "to" : { "x" : 2813, "y" : 277 } } ], "endShape" : { "a" : { "x" : 2817, "y" : 270 }, "b" : { "x" : 2813, "y" : 277 }, "c" : { "x" : 2821, "y" : 277 }, "type" : "ARROW", "centre" : { "x" : 2821, "y" : 277 } }, "reactionShape" : { "a" : { "x" : 2865, "y" : 235 }, "b" : { "x" : 2877, "y" : 247 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 2871, "y" : 241 } }, "inputs" : [ { "id" : 27452, "points" : [ { "x" : 2896, "y" : 280 } ] }, { "id" : 27411, "points" : [ { "x" : 2916, "y" : 197 } ] } ], "outputs" : [ { "id" : 27453 } ] }, { "id" : 27323, "reactomeId" : 10389319, "displayName" : "11cROL binds to RLBP1 to form RLBP1:11cROL", "schemaClass" : "Reaction", "renderableClass" : "Reaction", "position" : { "x" : 401, "y" : 170 }, "minX" : 395, "maxX" : 435, "minY" : 164, "maxY" : 176, "reactionType" : "binding", "segments" : [ { "from" : { "x" : 401, "y" : 171 }, "to" : { "x" : 401, "y" : 170 } }, { "from" : { "x" : 401, "y" : 170 }, "to" : { "x" : 435, "y" : 170 } } ], "endShape" : { "a" : { "x" : 428, "y" : 174 }, "b" : { "x" : 435, "y" : 170 }, "c" : { "x" : 428, "y" : 166 }, "type" : "ARROW", "centre" : { "x" : 428, "y" : 166 } }, "reactionShape" : { "c" : { "x" : 401, "y" : 170 }, "r" : 5, "type" : "CIRCLE", "centre" : { "x" : 401, "y" : 170 } }, "inputs" : [ { "id" : 27318, "points" : [ { "x" : 361, "y" : 180 } ] }, { "id" : 27324, "points" : [ { "x" : 366, "y" : 146 } ] } ], "outputs" : [ { "id" : 27325 } ] }, { "id" : 27454, "reactomeId" : 10337809, "displayName" : "GUCYs converts GTP to cGMP", "schemaClass" : "Reaction", "renderableClass" : "Reaction", "position" : { "x" : 2713, "y" : 247 }, "minX" : 2663, "maxX" : 2771, "minY" : 241, "maxY" : 253, "reactionType" : "transition", "segments" : [ { "from" : { "x" : 2771, "y" : 247 }, "to" : { "x" : 2713, "y" : 247 } }, { "from" : { "x" : 2713, "y" : 247 }, "to" : { "x" : 2663, "y" : 247 } } ], "reactionShape" : { "a" : { "x" : 2707, "y" : 241 }, "b" : { "x" : 2719, "y" : 253 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 2713, "y" : 247 } }, "inputs" : [ { "id" : 27455 } ], "outputs" : [ { "id" : 27456, "points" : [ { "x" : 2631, "y" : 247 } ] }, { "id" : 27401, "points" : [ { "x" : 2631, "y" : 204 } ] } ], "catalysts" : [ { "id" : 27457, "points" : [ { "x" : 2714, "y" : 277 } ] } ], "inhibitors" : [ { "id" : 27453, "points" : [ { "x" : 2778, "y" : 277 } ] }, { "id" : 27460, "points" : [ { "x" : 2781, "y" : 188 } ] }, { "id" : 27461, "points" : [ { "x" : 2796, "y" : 216 } ] } ], "activators" : [ { "id" : 27458, "points" : [ { "x" : 2690, "y" : 227 } ] }, { "id" : 27459, "points" : [ { "x" : 2716, "y" : 200 } ] } ] }, { "id" : 27390, "reactomeId" : 10389380, "displayName" : "atRAL is reduced to atROL", "schemaClass" : "Reaction", "renderableClass" : "Reaction", "position" : { "x" : 1429, "y" : 1052 }, "minX" : 1358, "maxX" : 1467, "minY" : 1046, "maxY" : 1058, "reactionType" : "transition", "segments" : [ { "from" : { "x" : 1467, "y" : 1052 }, "to" : { "x" : 1429, "y" : 1052 } }, { "from" : { "x" : 1429, "y" : 1052 }, "to" : { "x" : 1358, "y" : 1052 } } ], "reactionShape" : { "a" : { "x" : 1423, "y" : 1046 }, "b" : { "x" : 1435, "y" : 1058 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 1429, "y" : 1052 } }, "inputs" : [ { "id" : 27389, "points" : [ { "x" : 1522, "y" : 1052 } ] }, { "id" : 27391, "points" : [ { "x" : 1480, "y" : 1062 } ] }, { "id" : 27392, "points" : [ { "x" : 1480, "y" : 1038 } ] } ], "outputs" : [ { "id" : 27362, "points" : [ { "x" : 1324, "y" : 1042 } ] }, { "id" : 27393, "points" : [ { "x" : 1342, "y" : 1070 } ] } ], "catalysts" : [ { "id" : 27394, "points" : [ { "x" : 1429, "y" : 1014 } ] } ] }, { "id" : 27326, "reactomeId" : 10337774, "displayName" : "RDH10,11 oxidise 11cROL to 11cRAL", "schemaClass" : "Reaction", "renderableClass" : "Reaction", "position" : { "x" : 604, "y" : 168 }, "minX" : 575, "maxX" : 639, "minY" : 162, "maxY" : 174, "reactionType" : "transition", "segments" : [ { "from" : { "x" : 575, "y" : 168 }, "to" : { "x" : 604, "y" : 168 } }, { "from" : { "x" : 604, "y" : 168 }, "to" : { "x" : 639, "y" : 168 } } ], "reactionShape" : { "a" : { "x" : 598, "y" : 162 }, "b" : { "x" : 610, "y" : 174 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 604, "y" : 168 } }, "inputs" : [ { "id" : 27325, "points" : [ { "x" : 538, "y" : 169 } ] }, { "id" : 27327, "points" : [ { "x" : 554, "y" : 153 } ] } ], "outputs" : [ { "id" : 27328, "points" : [ { "x" : 713, "y" : 168 } ] }, { "id" : 27329, "points" : [ { "x" : 647, "y" : 147 } ] }, { "id" : 27330, "points" : [ { "x" : 673, "y" : 150 } ] } ], "catalysts" : [ { "id" : 27331, "points" : [ { "x" : 605, "y" : 190 } ] } ] } ], "compartments" : [ { "id" : 27520, "reactomeId" : 263698, "displayName" : "phagolysosome", "schemaClass" : "Compartment", "renderableClass" : "Compartment", "position" : { "x" : 1088, "y" : 916 }, "minX" : 1022, "maxX" : 1154, "minY" : 869, "maxY" : 964, "prop" : { "x" : 1022, "y" : 869, "width" : 132, "height" : 95 }, "textPosition" : { "x" : 1031, "y" : 916 }, "insets" : { "x" : 1032, "y" : 879, "width" : 112, "height" : 75 }, "bgColor" : { "r" : 250, "g" : 240, "b" : 240 } }, { "id" : 27490, "reactomeId" : 70101, "displayName" : "cytosol", "schemaClass" : "Compartment", "renderableClass" : "Compartment", "position" : { "x" : 593, "y" : 452 }, "minX" : 216, "maxX" : 970, "minY" : 95, "maxY" : 810, "prop" : { "x" : 216, "y" : 95, "width" : 754, "height" : 715 }, "textPosition" : { "x" : 741, "y" : 460 }, "insets" : { "x" : 226, "y" : 105, "width" : 734, "height" : 695 }, "bgColor" : { "r" : 250, "g" : 240, "b" : 240 }, "componentIds" : [ 27492, 27308, 27311, 27316, 27321, 27320, 27326, 27328, 27329, 27330, 27493, 27318, 27323, 27325, 27327, 27334, 27335, 27494, 27491, 27322, 27333, 27332, 27303, 27304, 27306, 27301, 27305, 27309, 27307, 27314, 27310, 27324, 27467, 27471, 27472, 27468, 27466, 27469, 27470, 27473, 27338, 27481, 27547, 27548, 27549, 27317, 27312 ] }, { "id" : 27491, "reactomeId" : 17957, "displayName" : "endoplasmic reticulum lumen", "schemaClass" : "Compartment", "renderableClass" : "Compartment", "position" : { "x" : 453, "y" : 477 }, "minX" : 381, "maxX" : 525, "minY" : 431, "maxY" : 524, "prop" : { "x" : 381, "y" : 431, "width" : 144, "height" : 93 }, "textPosition" : { "x" : 395, "y" : 447 }, "insets" : { "x" : 391, "y" : 441, "width" : 124, "height" : 73 }, "bgColor" : { "r" : 250, "g" : 240, "b" : 240 }, "componentIds" : [ 27315, 27474 ] }, { "id" : 27492, "reactomeId" : 13977, "displayName" : "lipid droplet", "schemaClass" : "Compartment", "renderableClass" : "Compartment", "position" : { "x" : 311, "y" : 362 }, "minX" : 240, "maxX" : 383, "minY" : 298, "maxY" : 427, "prop" : { "x" : 240, "y" : 298, "width" : 143, "height" : 129 }, "textPosition" : { "x" : 281, "y" : 353 }, "insets" : { "x" : 250, "y" : 308, "width" : 123, "height" : 109 }, "bgColor" : { "r" : 250, "g" : 240, "b" : 240 }, "componentIds" : [ 27313, 27319 ] }, { "id" : 27493, "reactomeId" : 17957, "displayName" : "endoplasmic reticulum lumen", "schemaClass" : "Compartment", "renderableClass" : "Compartment", "position" : { "x" : 621, "y" : 256 }, "minX" : 522, "maxX" : 720, "minY" : 201, "maxY" : 311, "prop" : { "x" : 522, "y" : 201, "width" : 198, "height" : 110 }, "textPosition" : { "x" : 521, "y" : 239 }, "insets" : { "x" : 532, "y" : 211, "width" : 178, "height" : 90 }, "bgColor" : { "r" : 250, "g" : 240, "b" : 240 }, "componentIds" : [ 27331, 27336 ] }, { "id" : 27526, "reactomeId" : 2514888, "displayName" : "photoreceptor disc membrane", "schemaClass" : "Compartment", "renderableClass" : "Compartment", "position" : { "x" : 2021, "y" : 352 }, "minX" : 1059, "maxX" : 2983, "minY" : 292, "maxY" : 413, "prop" : { "x" : 1059, "y" : 292, "width" : 1924, "height" : 121 }, "textPosition" : { "x" : 2298, "y" : 322 }, "bgColor" : { "r" : 250, "g" : 240, "b" : 240 }, "componentIds" : [ 27533, 27428, 27437, 27440, 27446, 27341, 27545, 27488 ] }, { "id" : 27495, "reactomeId" : 70101, "displayName" : "cytosol", "schemaClass" : "Compartment", "renderableClass" : "Compartment", "position" : { "x" : 2058, "y" : 458 }, "minX" : 1018, "maxX" : 3098, "minY" : 62, "maxY" : 854, "prop" : { "x" : 1018, "y" : 62, "width" : 2080, "height" : 792 }, "textPosition" : { "x" : 2289, "y" : 529 }, "insets" : { "x" : 1028, "y" : 72, "width" : 2060, "height" : 772 }, "bgColor" : { "r" : 250, "g" : 240, "b" : 240 }, "componentIds" : [ 27339, 27347, 27348, 27349, 27350, 27351, 27345, 27353, 27354, 27496, 27358, 27523, 27526, 27395, 27399, 27402, 27411, 27410, 27414, 27412, 27416, 27417, 27420, 27421, 27413, 27415, 27422, 27426, 27427, 27424, 27400, 27534, 27442, 27444, 27443, 27445, 27447, 27454, 27401, 27357, 27356, 27405, 27406, 27462, 27456, 27455, 27451, 27355, 27434, 27540, 27465, 27436, 27438, 27429, 27431, 27407, 27404, 27463, 27464, 27475, 27477, 27478, 27480, 27479, 27476, 27459, 27460, 27461, 27458, 27418 ] }, { "id" : 27497, "reactomeId" : 70101, "displayName" : "cytosol", "schemaClass" : "Compartment", "renderableClass" : "Compartment", "position" : { "x" : 536, "y" : 1191 }, "minX" : 200, "maxX" : 872, "minY" : 989, "maxY" : 1393, "prop" : { "x" : 200, "y" : 989, "width" : 672, "height" : 404 }, "textPosition" : { "x" : 585, "y" : 1195 }, "insets" : { "x" : 210, "y" : 999, "width" : 652, "height" : 384 }, "bgColor" : { "r" : 250, "g" : 240, "b" : 240 }, "componentIds" : [ 27367, 27365, 27370, 27499, 27498, 27368, 27369, 27371, 27375, 27363, 27372, 27366 ] }, { "id" : 27499, "reactomeId" : 17957, "displayName" : "endoplasmic reticulum lumen", "schemaClass" : "Compartment", "renderableClass" : "Compartment", "position" : { "x" : 577, "y" : 1118 }, "minX" : 438, "maxX" : 717, "minY" : 1082, "maxY" : 1155, "prop" : { "x" : 438, "y" : 1082, "width" : 279, "height" : 73 }, "textPosition" : { "x" : 516, "y" : 1100 }, "insets" : { "x" : 448, "y" : 1092, "width" : 259, "height" : 53 }, "bgColor" : { "r" : 250, "g" : 240, "b" : 240 }, "componentIds" : [ 27373 ] }, { "id" : 27533, "reactomeId" : 2514888, "displayName" : "photoreceptor disc membrane", "schemaClass" : "Compartment", "renderableClass" : "Compartment", "position" : { "x" : 2021, "y" : 351 }, "minX" : 1068, "maxX" : 2974, "minY" : 300, "maxY" : 403, "prop" : { "x" : 1068, "y" : 300, "width" : 1906, "height" : 103 }, "textPosition" : { "x" : 2022, "y" : 327 }, "bgColor" : { "r" : 250, "g" : 240, "b" : 240 }, "componentIds" : [ 27419, 27423, 27425, 27435, 27439, 27441, 27346, 27352, 27342, 27397, 27398, 27448, 27403, 27449, 27450, 27457, 27396, 27452, 27453, 27343, 27430, 27432, 27433, 27344 ] }, { "id" : 27504, "reactomeId" : 70101, "displayName" : "cytosol", "schemaClass" : "Compartment", "renderableClass" : "Compartment", "position" : { "x" : 1543, "y" : 1172 }, "minX" : 956, "maxX" : 2131, "minY" : 997, "maxY" : 1348, "prop" : { "x" : 956, "y" : 997, "width" : 1175, "height" : 351 }, "textPosition" : { "x" : 979, "y" : 1069 }, "insets" : { "x" : 966, "y" : 1007, "width" : 1155, "height" : 331 }, "bgColor" : { "r" : 250, "g" : 240, "b" : 240 }, "componentIds" : [ 27508, 27377, 27389, 27390, 27393, 27391, 27392, 27382, 27376, 27362, 27394, 27544, 27387, 27386, 27379, 27383, 27486, 27483, 27378, 27380, 27484, 27487, 27550, 27551, 27552, 27381, 27482, 27485 ] }, { "id" : 27538, "reactomeId" : 2514888, "displayName" : "photoreceptor disc membrane", "schemaClass" : "Compartment", "renderableClass" : "Compartment", "position" : { "x" : 1524, "y" : 662 }, "minX" : 1294, "maxX" : 1755, "minY" : 634, "maxY" : 690, "prop" : { "x" : 1294, "y" : 634, "width" : 461, "height" : 56 }, "textPosition" : { "x" : 1297, "y" : 645 }, "bgColor" : { "r" : 250, "g" : 240, "b" : 240 } }, { "id" : 27508, "reactomeId" : 17957, "displayName" : "endoplasmic reticulum lumen", "schemaClass" : "Compartment", "renderableClass" : "Compartment", "position" : { "x" : 1170, "y" : 1115 }, "minX" : 1106, "maxX" : 1234, "minY" : 1075, "maxY" : 1156, "prop" : { "x" : 1106, "y" : 1075, "width" : 128, "height" : 81 }, "textPosition" : { "x" : 1111, "y" : 1093 }, "insets" : { "x" : 1116, "y" : 1085, "width" : 108, "height" : 61 }, "bgColor" : { "r" : 250, "g" : 240, "b" : 240 }, "componentIds" : [ 27509 ] }, { "id" : 27540, "reactomeId" : 2514888, "displayName" : "photoreceptor disc membrane", "schemaClass" : "Compartment", "renderableClass" : "Compartment", "position" : { "x" : 1524, "y" : 662 }, "minX" : 1288, "maxX" : 1760, "minY" : 628, "maxY" : 697, "prop" : { "x" : 1288, "y" : 628, "width" : 472, "height" : 69 }, "textPosition" : { "x" : 1297, "y" : 645 }, "bgColor" : { "r" : 250, "g" : 240, "b" : 240 }, "componentIds" : [ 27538 ] }, { "id" : 27544, "reactomeId" : 2514888, "displayName" : "photoreceptor disc membrane", "schemaClass" : "Compartment", "renderableClass" : "Compartment", "position" : { "x" : 1694, "y" : 1148 }, "minX" : 1357, "maxX" : 2031, "minY" : 1124, "maxY" : 1173, "prop" : { "x" : 1357, "y" : 1124, "width" : 674, "height" : 49 }, "textPosition" : { "x" : 1497, "y" : 1131 }, "bgColor" : { "r" : 250, "g" : 240, "b" : 240 }, "componentIds" : [ 27388, 27385 ] } ], "notes" : [ { "id" : 27523, "displayName" : "Rod inner segment", "renderableClass" : "Note", "position" : { "x" : 2319, "y" : 799 }, "minX" : 2282, "maxX" : 2357, "minY" : 781, "maxY" : 817, "prop" : { "x" : 2282, "y" : 781, "width" : 75, "height" : 36 }, "textPosition" : { "x" : 2283, "y" : 781 } }, { "id" : 27509, "displayName" : "Cone outer segment", "renderableClass" : "Note", "position" : { "x" : 1034, "y" : 1066 }, "minX" : 961, "maxX" : 1107, "minY" : 1051, "maxY" : 1081, "prop" : { "x" : 961, "y" : 1051, "width" : 146, "height" : 30 }, "textPosition" : { "x" : 965, "y" : 1055 } }, { "id" : 27494, "displayName" : "RPE", "renderableClass" : "Note", "position" : { "x" : 768, "y" : 456 }, "minX" : 743, "maxX" : 793, "minY" : 445, "maxY" : 467, "prop" : { "x" : 743, "y" : 445, "width" : 50, "height" : 22 }, "textPosition" : { "x" : 752, "y" : 445 } }, { "id" : 27496, "displayName" : "Rod outer segment", "renderableClass" : "Note", "position" : { "x" : 1321, "y" : 723 }, "minX" : 1264, "maxX" : 1379, "minY" : 707, "maxY" : 740, "prop" : { "x" : 1264, "y" : 707, "width" : 115, "height" : 33 }, "textPosition" : { "x" : 1284, "y" : 706 } }, { "id" : 27498, "displayName" : "Muller cell", "renderableClass" : "Note", "position" : { "x" : 616, "y" : 1191 }, "minX" : 568, "maxX" : 664, "minY" : 1175, "maxY" : 1207, "prop" : { "x" : 568, "y" : 1175, "width" : 96, "height" : 32 }, "textPosition" : { "x" : 581, "y" : 1180 } } ], "links" : [ { "id" : 27552, "renderableClass" : "EntitySetAndMemberLink", "position" : { "x" : 1717, "y" : 1245 }, "minX" : 1688, "maxX" : 1746, "minY" : 1239, "maxY" : 1251, "segments" : [ { "from" : { "x" : 1688, "y" : 1240 }, "to" : { "x" : 1746, "y" : 1250 } } ], "reactionShape" : { "a" : { "x" : 1711, "y" : 1239 }, "b" : { "x" : 1723, "y" : 1251 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 1717, "y" : 1245 } }, "inputs" : [ { "id" : 27487 } ], "outputs" : [ { "id" : 27383 } ] }, { "id" : 27545, "renderableClass" : "EntitySetAndMemberLink", "position" : { "x" : 1865, "y" : 410 }, "minX" : 1856, "maxX" : 1874, "minY" : 346, "maxY" : 475, "segments" : [ { "from" : { "x" : 1874, "y" : 475 }, "to" : { "x" : 1856, "y" : 346 } } ], "reactionShape" : { "a" : { "x" : 1859, "y" : 404 }, "b" : { "x" : 1871, "y" : 416 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 1865, "y" : 410 } }, "inputs" : [ { "id" : 27534 } ], "outputs" : [ { "id" : 27433 } ] }, { "id" : 27546, "renderableClass" : "Interaction", "position" : { "x" : 148, "y" : 872 }, "minX" : 130, "maxX" : 166, "minY" : 866, "maxY" : 878, "interactionType" : "Activate", "segments" : [ { "from" : { "x" : 130, "y" : 872 }, "to" : { "x" : 166, "y" : 872 } } ], "endShape" : { "a" : { "x" : 159, "y" : 876 }, "b" : { "x" : 166, "y" : 872 }, "c" : { "x" : 159, "y" : 868 }, "type" : "ARROW", "empty" : true, "centre" : { "x" : 159, "y" : 868 } }, "reactionShape" : { "a" : { "x" : 142, "y" : 866 }, "b" : { "x" : 154, "y" : 878 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 148, "y" : 872 } }, "inputs" : [ { "id" : 27543 } ], "outputs" : [ { "id" : 27302 } ] }, { "id" : 27547, "renderableClass" : "EntitySetAndMemberLink", "position" : { "x" : 1355, "y" : 1191 }, "minX" : 1327, "maxX" : 1383, "minY" : 1167, "maxY" : 1216, "segments" : [ { "from" : { "x" : 1327, "y" : 1216 }, "to" : { "x" : 1383, "y" : 1167 } } ], "reactionShape" : { "a" : { "x" : 1349, "y" : 1185 }, "b" : { "x" : 1361, "y" : 1197 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 1355, "y" : 1191 } }, "inputs" : [ { "id" : 27486 } ], "outputs" : [ { "id" : 27388 } ] }, { "id" : 27548, "renderableClass" : "EntitySetAndMemberLink", "position" : { "x" : 1443, "y" : 1173 }, "minX" : 1421, "maxX" : 1466, "minY" : 1167, "maxY" : 1180, "segments" : [ { "from" : { "x" : 1466, "y" : 1180 }, "to" : { "x" : 1421, "y" : 1167 } } ], "reactionShape" : { "a" : { "x" : 1437, "y" : 1167 }, "b" : { "x" : 1449, "y" : 1179 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 1443, "y" : 1173 } }, "inputs" : [ { "id" : 27483 } ], "outputs" : [ { "id" : 27388 } ] }, { "id" : 27549, "renderableClass" : "EntitySetAndMemberLink", "position" : { "x" : 1405, "y" : 1185 }, "minX" : 1398, "maxX" : 1412, "minY" : 1167, "maxY" : 1204, "segments" : [ { "from" : { "x" : 1412, "y" : 1204 }, "to" : { "x" : 1398, "y" : 1167 } } ], "reactionShape" : { "a" : { "x" : 1399, "y" : 1179 }, "b" : { "x" : 1411, "y" : 1191 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 1405, "y" : 1185 } }, "inputs" : [ { "id" : 27378 } ], "outputs" : [ { "id" : 27388 } ] }, { "id" : 27550, "renderableClass" : "EntitySetAndMemberLink", "position" : { "x" : 1716, "y" : 1262 }, "minX" : 1687, "maxX" : 1746, "minY" : 1256, "maxY" : 1268, "segments" : [ { "from" : { "x" : 1687, "y" : 1263 }, "to" : { "x" : 1746, "y" : 1261 } } ], "reactionShape" : { "a" : { "x" : 1710, "y" : 1256 }, "b" : { "x" : 1722, "y" : 1268 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 1716, "y" : 1262 } }, "inputs" : [ { "id" : 27380 } ], "outputs" : [ { "id" : 27383 } ] }, { "id" : 27551, "renderableClass" : "EntitySetAndMemberLink", "position" : { "x" : 1708, "y" : 1278 }, "minX" : 1670, "maxX" : 1746, "minY" : 1270, "maxY" : 1287, "segments" : [ { "from" : { "x" : 1670, "y" : 1287 }, "to" : { "x" : 1746, "y" : 1270 } } ], "reactionShape" : { "a" : { "x" : 1702, "y" : 1272 }, "b" : { "x" : 1714, "y" : 1284 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 1708, "y" : 1278 } }, "inputs" : [ { "id" : 27484 } ], "outputs" : [ { "id" : 27383 } ] } ], "shadows" : [ { "id" : 27553, "reactomeId" : 10443042, "displayName" : "The phototransduction cascade", "schemaClass" : "Pathway", "renderableClass" : "Shadow", "position" : { "x" : 2102, "y" : 314 }, "minX" : 1039, "maxX" : 3165, "minY" : -9, "maxY" : 638, "prop" : { "x" : 2228, "y" : 1, "width" : 937, "height" : 637 }, "points" : [ { "x" : 1039, "y" : -9 }, { "x" : 3165, "y" : -9 }, { "x" : 3165, "y" : 638 }, { "x" : 1039, "y" : 638 } ], "colour" : "#4684ee" }, { "id" : 27554, "reactomeId" : 10443050, "displayName" : "The canonical retinoid cycle in rods (twilight vision)", "schemaClass" : "Pathway", "renderableClass" : "Shadow", "position" : { "x" : 1193, "y" : 493 }, "minX" : 159, "maxX" : 2228, "minY" : 1, "maxY" : 986, "prop" : { "x" : 159, "y" : 638, "width" : 2069, "height" : 341 }, "points" : [ { "x" : 159, "y" : 1 }, { "x" : 2228, "y" : 1 }, { "x" : 2228, "y" : 986 }, { "x" : 159, "y" : 986 } ], "colour" : "#dc3912" }, { "id" : 27555, "reactomeId" : 10445262, "displayName" : "The retinoid cycle in cones (daylight vision)", "schemaClass" : "Pathway", "renderableClass" : "Shadow", "position" : { "x" : 1127, "y" : 1189 }, "minX" : 263, "maxX" : 1991, "minY" : 979, "maxY" : 1399, "prop" : { "x" : 263, "y" : 986, "width" : 1728, "height" : 413 }, "points" : [ { "x" : 263, "y" : 979 }, { "x" : 1991, "y" : 979 }, { "x" : 1991, "y" : 1399 }, { "x" : 263, "y" : 1399 } ], "colour" : "#008000" } ], "minX" : 0, "maxX" : 3161, "minY" : 0, "maxY" : 1393, "disease" : false }