{
  "dbId" : 10443902,
  "stId" : "R-BTA-194138",
  "speciesName" : "Bos taurus",
  "nodes" : [ {
    "dbId" : 10341533,
    "stId" : "R-BTA-200917",
    "displayName" : "FYN [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48898,
    "diagramIds" : [ 97444 ],
    "identifier" : "A0JNB0",
    "standardIdentifier" : "uniprot:A0JNB0",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 10397998 ],
    "children" : [ ]
  }, {
    "dbId" : 10395294,
    "stId" : "R-BTA-5218635",
    "displayName" : "VEGFA:p-6Y-VEGFR2:p-SHB:p-5Y-PTK2 [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 48898,
    "parents" : [ 10395296 ],
    "children" : [ 10395290, 10395292 ]
  }, {
    "dbId" : 10375839,
    "stId" : "R-BTA-171012",
    "displayName" : "MAPK13 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48898,
    "identifier" : "Q5E9Q6",
    "standardIdentifier" : "uniprot:Q5E9Q6",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "MAPK13" ],
    "parents" : [ 10397951 ],
    "children" : [ ]
  }, {
    "dbId" : 10349724,
    "stId" : "R-BTA-215140",
    "displayName" : "VEGFR3 dimer:VEGFC, VEGFD dimers [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 48898,
    "diagramIds" : [ 97285 ],
    "parents" : [ ],
    "children" : [ 10349716, 10349722 ]
  }, {
    "dbId" : 10395292,
    "stId" : "R-BTA-5218711",
    "displayName" : "phospho-p-5Y-PTK2 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48898,
    "identifier" : "A0A3Q1MAA1",
    "standardIdentifier" : "uniprot:A0A3Q1MAA1",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 10395294 ],
    "children" : [ ]
  }, {
    "dbId" : 10395290,
    "stId" : "R-BTA-4420164",
    "displayName" : "VEGFA dimer:p-6Y-VEGFR2 dimer:p-S-SHB [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 48898,
    "diagramIds" : [ 97302 ],
    "parents" : [ 10395294, 10396049, 10397937, 10398116, 10398010 ],
    "children" : [ 10395283, 10395288 ]
  }, {
    "dbId" : 10375835,
    "stId" : "R-BTA-170989",
    "displayName" : "MAPK11 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48898,
    "identifier" : "G3X793",
    "standardIdentifier" : "uniprot:G3X793",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 10397951 ],
    "children" : [ ]
  }, {
    "dbId" : 10349720,
    "stId" : "R-BTA-195359",
    "displayName" : "FLT4 [plasma membrane]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48898,
    "diagramIds" : [ 97283 ],
    "identifier" : "F1MHP5",
    "standardIdentifier" : "uniprot:F1MHP5",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 10349722 ],
    "children" : [ ]
  }, {
    "dbId" : 10395288,
    "stId" : "R-BTA-5228991",
    "displayName" : "phospho-SHB [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48898,
    "identifier" : "E1BLY9",
    "standardIdentifier" : "uniprot:E1BLY9",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "SHB" ],
    "parents" : [ 10395290 ],
    "children" : [ ]
  }, {
    "dbId" : 10349722,
    "stId" : "R-BTA-195405",
    "displayName" : "VEGFR3 dimer [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 48898,
    "parents" : [ 10349724 ],
    "children" : [ 10349720 ]
  }, {
    "dbId" : 10349716,
    "stId" : "R-BTA-195391",
    "displayName" : "VEGFC,VEGFD dimers [extracellular region]",
    "schemaClass" : "DefinedSet",
    "speciesId" : 48898,
    "diagramIds" : [ 97284 ],
    "parents" : [ 10349724 ],
    "children" : [ 10349714, 10349708 ]
  }, {
    "dbId" : 10395283,
    "stId" : "R-BTA-4420101",
    "displayName" : "VEGFA dimer:p-6Y-VEGFR2 dimer [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 48898,
    "diagramIds" : [ 97362, 97295 ],
    "parents" : [ 10396063, 10397955, 10396055, 10398073, 10395290, 10396084, 10398077, 10396072, 10396074 ],
    "children" : [ 10395281, 10395271 ]
  }, {
    "dbId" : 10349712,
    "stId" : "R-BTA-139888",
    "displayName" : "VEGFD [extracellular region]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48898,
    "identifier" : "A7MBB6",
    "standardIdentifier" : "uniprot:A7MBB6",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "VEGFD" ],
    "parents" : [ 10349714, 10349928 ],
    "children" : [ ]
  }, {
    "dbId" : 10360976,
    "stId" : "R-BTA-390932",
    "displayName" : "PTK2B [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48898,
    "diagramIds" : [ 97335 ],
    "identifier" : "A0A3Q1LVP1",
    "standardIdentifier" : "uniprot:A0A3Q1LVP1",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 10398135 ],
    "children" : [ ]
  }, {
    "dbId" : 10395281,
    "stId" : "R-BTA-4420096",
    "displayName" : "p-6Y-VEGFR2 dimer [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 48898,
    "parents" : [ 10395283 ],
    "children" : [ 10395279 ]
  }, {
    "dbId" : 10349714,
    "stId" : "R-BTA-195355",
    "displayName" : "VEGFD dimer [extracellular region]",
    "schemaClass" : "Complex",
    "speciesId" : 48898,
    "parents" : [ 10349716, 10349734, 10349930 ],
    "children" : [ 10349712 ]
  }, {
    "dbId" : 71185,
    "stId" : "R-ALL-71185",
    "displayName" : "ferroheme [cytosol]",
    "schemaClass" : "SimpleEntity",
    "speciesId" : 0,
    "identifier" : "60344",
    "standardIdentifier" : "chebi:60344",
    "referenceType" : "ReferenceMolecule",
    "parents" : [ 10398129, 10352236, 10352202 ],
    "children" : [ ]
  }, {
    "dbId" : 10395279,
    "stId" : "R-BTA-4420103",
    "displayName" : "phospho-p-6Y-VEGFR2 [plasma membrane]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48898,
    "identifier" : "F1MWF1",
    "standardIdentifier" : "uniprot:F1MWF1",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 10395281 ],
    "children" : [ ]
  }, {
    "dbId" : 10352268,
    "stId" : "R-BTA-202210",
    "displayName" : "PDPK1 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48898,
    "diagramIds" : [ 97403 ],
    "identifier" : "F1MQJ7",
    "standardIdentifier" : "uniprot:F1MQJ7",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ ],
    "children" : [ ]
  }, {
    "dbId" : 10349708,
    "stId" : "R-BTA-195360",
    "displayName" : "VEGFC dimer [extracellular region]",
    "schemaClass" : "Complex",
    "speciesId" : 48898,
    "parents" : [ 10349716, 10349734, 10349930 ],
    "children" : [ 10349706 ]
  }, {
    "dbId" : 10341515,
    "stId" : "R-BTA-57600",
    "displayName" : "ITGB3 [plasma membrane]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48898,
    "identifier" : "F1MTN1",
    "standardIdentifier" : "uniprot:F1MTN1",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "ITGB3" ],
    "parents" : [ 10354217 ],
    "children" : [ ]
  }, {
    "dbId" : 10349706,
    "stId" : "R-BTA-139887",
    "displayName" : "VEGFC [extracellular region]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48898,
    "identifier" : "Q9XS50",
    "standardIdentifier" : "uniprot:Q9XS50",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "VEGFC" ],
    "parents" : [ 10349708, 10349928 ],
    "children" : [ ]
  }, {
    "dbId" : 10395271,
    "stId" : "R-BTA-4420158",
    "displayName" : "VEGFA-165 dimer [extracellular region]",
    "schemaClass" : "Complex",
    "speciesId" : 48898,
    "diagramIds" : [ 97522 ],
    "parents" : [ 10433984, 10396067, 10395283 ],
    "children" : [ 10395269 ]
  }, {
    "dbId" : 10352263,
    "stId" : "R-BTA-163510",
    "displayName" : "CAV1 [lipid droplet]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48898,
    "diagramIds" : [ 97414 ],
    "identifier" : "P79132",
    "standardIdentifier" : "uniprot:P79132",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "CAV1" ],
    "parents" : [ ],
    "children" : [ ]
  }, {
    "dbId" : 10395269,
    "stId" : "R-BTA-4420127",
    "displayName" : "VEGFA [extracellular region]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48898,
    "identifier" : "P15691",
    "standardIdentifier" : "uniprot:P15691",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "VEGFA" ],
    "parents" : [ 10395271 ],
    "children" : [ ]
  }, {
    "dbId" : 10349756,
    "stId" : "R-BTA-195367",
    "displayName" : "VEGFB dimer [extracellular region]",
    "schemaClass" : "Complex",
    "speciesId" : 48898,
    "parents" : [ 10349758, 10349930 ],
    "children" : [ 10349754 ]
  }, {
    "dbId" : 10349758,
    "stId" : "R-BTA-195389",
    "displayName" : "VEGFA,VEGFB,PGF dimers [extracellular region]",
    "schemaClass" : "DefinedSet",
    "speciesId" : 48898,
    "diagramIds" : [ 97275 ],
    "parents" : [ 10349766 ],
    "children" : [ 10349750, 10349732, 10349756 ]
  }, {
    "dbId" : 10349754,
    "stId" : "R-BTA-2975973",
    "displayName" : "VEGFB [extracellular region]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48898,
    "identifier" : "Q9XS49",
    "standardIdentifier" : "uniprot:Q9XS49",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "VEGFB" ],
    "parents" : [ 10349756, 10349928 ],
    "children" : [ ]
  }, {
    "dbId" : 10349748,
    "stId" : "R-BTA-3009042",
    "displayName" : "PGF [extracellular region]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48898,
    "identifier" : "Q9XS47",
    "standardIdentifier" : "uniprot:Q9XS47",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "PGF" ],
    "parents" : [ 10349750, 10349928 ],
    "children" : [ ]
  }, {
    "dbId" : 10349750,
    "stId" : "R-BTA-195352",
    "displayName" : "PGF dimer [extracellular region]",
    "schemaClass" : "Complex",
    "speciesId" : 48898,
    "parents" : [ 10349758, 10349930 ],
    "children" : [ 10349748 ]
  }, {
    "dbId" : 10349740,
    "stId" : "R-BTA-195403",
    "displayName" : "VEGFR2 dimer [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 48898,
    "parents" : [ 10349938, 10349742 ],
    "children" : [ 10349738 ]
  }, {
    "dbId" : 10361004,
    "stId" : "R-BTA-391267",
    "displayName" : "SPHK1 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48898,
    "diagramIds" : [ 97507 ],
    "identifier" : "F1MXZ6",
    "standardIdentifier" : "uniprot:F1MXZ6",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "SPHK1" ],
    "parents" : [ ],
    "children" : [ ]
  }, {
    "dbId" : 10349742,
    "stId" : "R-BTA-215139",
    "displayName" : "VEGFR2:VEGFA,C,D [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 48898,
    "diagramIds" : [ 97281 ],
    "parents" : [ ],
    "children" : [ 10349734, 10349740 ]
  }, {
    "dbId" : 10349738,
    "stId" : "R-BTA-195382",
    "displayName" : "VEGFR2 [plasma membrane]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48898,
    "diagramIds" : [ 97280 ],
    "identifier" : "F1MWF1",
    "standardIdentifier" : "uniprot:F1MWF1",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 10349740, 10396067 ],
    "children" : [ ]
  }, {
    "dbId" : 10349732,
    "stId" : "R-BTA-195364",
    "displayName" : "VEGFA dimer [extracellular region]",
    "schemaClass" : "Complex",
    "speciesId" : 48898,
    "diagramIds" : [ 97566 ],
    "parents" : [ 10349758, 10349734, 10349930 ],
    "children" : [ 10349730 ]
  }, {
    "dbId" : 10349734,
    "stId" : "R-BTA-195393",
    "displayName" : "VEGFA,C,D dimers [extracellular region]",
    "schemaClass" : "DefinedSet",
    "speciesId" : 48898,
    "diagramIds" : [ 97279 ],
    "parents" : [ 10349742 ],
    "children" : [ 10349714, 10349732, 10349708 ]
  }, {
    "dbId" : 10395298,
    "stId" : "R-BTA-5218637",
    "displayName" : "VEGFA:p-6Y-VEGFR2:p-SHB:p-5Y-PTK2:SRC-1:HSP90AA1 [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 48898,
    "diagramIds" : [ 97323 ],
    "parents" : [ ],
    "children" : [ 10395296, 10352229 ]
  }, {
    "dbId" : 10395296,
    "stId" : "R-BTA-5218636",
    "displayName" : "VEGFA:p-6Y-VEGFR2:p-SHB:p-5Y-PTK2:SRC-1 [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 48898,
    "diagramIds" : [ 97316 ],
    "parents" : [ 10395298 ],
    "children" : [ 10348836, 10395294 ]
  }, {
    "dbId" : 10375841,
    "stId" : "R-BTA-171025",
    "displayName" : "MAPK12 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48898,
    "identifier" : "A5PJL3",
    "standardIdentifier" : "uniprot:A5PJL3",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 10397951 ],
    "children" : [ ]
  }, {
    "dbId" : 10349730,
    "stId" : "R-BTA-2975974",
    "displayName" : "VEGFA [extracellular region]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48898,
    "identifier" : "P15691",
    "standardIdentifier" : "uniprot:P15691",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "VEGFA" ],
    "parents" : [ 10349928, 10349732 ],
    "children" : [ ]
  }, {
    "dbId" : 352327,
    "stId" : "R-ALL-352327",
    "displayName" : "O2 [extracellular region]",
    "schemaClass" : "SimpleEntity",
    "speciesId" : 0,
    "diagramIds" : [ 97436 ],
    "identifier" : "15379",
    "standardIdentifier" : "chebi:15379",
    "referenceType" : "ReferenceMolecule",
    "parents" : [ ],
    "children" : [ ]
  }, {
    "dbId" : 10340057,
    "stId" : "R-BTA-109697",
    "displayName" : "PDPK1:PIP3 [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 48898,
    "diagramIds" : [ 97405 ],
    "parents" : [ ],
    "children" : [ 179838, 10340055 ]
  }, {
    "dbId" : 10340055,
    "stId" : "R-BTA-61459",
    "displayName" : "PDPK1 [plasma membrane]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48898,
    "diagramIds" : [ 97496 ],
    "identifier" : "F1MQJ7",
    "standardIdentifier" : "uniprot:F1MQJ7",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 10340057 ],
    "children" : [ ]
  }, {
    "dbId" : 10349764,
    "stId" : "R-BTA-195398",
    "displayName" : "VEGFR1 dimer [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 48898,
    "parents" : [ 10349766, 10349946 ],
    "children" : [ 10349762 ]
  }, {
    "dbId" : 10349766,
    "stId" : "R-BTA-195396",
    "displayName" : "VEGFR1 dimer:VEGFA, VEGFB, PGF dimers [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 48898,
    "diagramIds" : [ 97277 ],
    "parents" : [ ],
    "children" : [ 10349764, 10349758 ]
  }, {
    "dbId" : 10349762,
    "stId" : "R-BTA-3004464",
    "displayName" : "VEGFR1 [plasma membrane]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48898,
    "diagramIds" : [ 97276 ],
    "identifier" : "F1MDD9",
    "standardIdentifier" : "uniprot:F1MDD9",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 10349764 ],
    "children" : [ ]
  }, {
    "dbId" : 10366657,
    "stId" : "R-BTA-450563",
    "displayName" : "HSPB1 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48898,
    "identifier" : "Q3T149",
    "standardIdentifier" : "uniprot:Q3T149",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "HSPB1" ],
    "parents" : [ 10398185 ],
    "children" : [ ]
  }, {
    "dbId" : 10397951,
    "stId" : "R-BTA-171016",
    "displayName" : "MAP kinase p38 [cytosol]",
    "schemaClass" : "DefinedSet",
    "speciesId" : 48898,
    "parents" : [ 10397953 ],
    "children" : [ 10375841, 10375835, 10375839, 10363806 ]
  }, {
    "dbId" : 10385143,
    "stId" : "R-BTA-2029115",
    "displayName" : "p-VAV family [cytosol]",
    "schemaClass" : "DefinedSet",
    "speciesId" : 48898,
    "parents" : [ 10398094 ],
    "children" : [ 10364881, 10364849, 10364869 ]
  }, {
    "dbId" : 10397939,
    "stId" : "R-BTA-5218641",
    "displayName" : "VEGFA:p-6Y-VEGFR2:p-SHB:p-Y397-PTK2:SRC-1 [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 48898,
    "diagramIds" : [ 97313, 97395, 97341 ],
    "parents" : [ ],
    "children" : [ 10397937, 10348836 ]
  }, {
    "dbId" : 10397937,
    "stId" : "R-BTA-5218639",
    "displayName" : "VEGFA:p-6Y-VEGFR2:p-SHB:p-Y397-PTK2 [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 48898,
    "diagramIds" : [ 97310 ],
    "parents" : [ 10397939 ],
    "children" : [ 10356165, 10395290 ]
  }, {
    "dbId" : 179838,
    "stId" : "R-ALL-179838",
    "displayName" : "PI(3,4,5)P3 [plasma membrane]",
    "schemaClass" : "SimpleEntity",
    "speciesId" : 0,
    "diagramIds" : [ 97404, 97388 ],
    "identifier" : "57836",
    "standardIdentifier" : "chebi:57836",
    "referenceType" : "ReferenceMolecule",
    "parents" : [ 10364856, 10398094, 10340057 ],
    "children" : [ ]
  }, {
    "dbId" : 10346013,
    "stId" : "R-BTA-9647915",
    "displayName" : "KRAS [plasma membrane]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48898,
    "identifier" : "E1BMX0",
    "standardIdentifier" : "uniprot:E1BMX0",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "KRAS" ],
    "parents" : [ 10346031 ],
    "children" : [ ]
  }, {
    "dbId" : 10399259,
    "stId" : "R-BTA-5357442",
    "displayName" : "VEGFA:p-6Y-VEGFR2:SH2D2A:p-Y418-SRC-1:AXL [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 48898,
    "diagramIds" : [ 97376 ],
    "parents" : [ ],
    "children" : [ 10396096, 10399257 ]
  }, {
    "dbId" : 10399257,
    "stId" : "R-BTA-197705",
    "displayName" : "AXL [plasma membrane]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48898,
    "diagramIds" : [ 97375 ],
    "identifier" : "A0A3Q1MRN2",
    "standardIdentifier" : "uniprot:A0A3Q1MRN2",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 10399259 ],
    "children" : [ ]
  }, {
    "dbId" : 10361359,
    "stId" : "R-BTA-399836",
    "displayName" : "p-S,T-PAK1,2,3 [cytosol]",
    "schemaClass" : "DefinedSet",
    "speciesId" : 48898,
    "diagramIds" : [ 97401 ],
    "parents" : [ ],
    "children" : [ 10361349, 10361353, 10361357 ]
  }, {
    "dbId" : 112275,
    "stId" : "R-ALL-112275",
    "displayName" : "DAGs [plasma membrane]",
    "schemaClass" : "SimpleEntity",
    "speciesId" : 0,
    "diagramIds" : [ 97502 ],
    "identifier" : "18035",
    "standardIdentifier" : "chebi:18035",
    "referenceType" : "ReferenceMolecule",
    "parents" : [ 10398060 ],
    "children" : [ ]
  }, {
    "dbId" : 179856,
    "stId" : "R-ALL-179856",
    "displayName" : "PI(4,5)P2 [plasma membrane]",
    "schemaClass" : "SimpleEntity",
    "speciesId" : 0,
    "diagramIds" : [ 97386 ],
    "identifier" : "58456",
    "standardIdentifier" : "chebi:58456",
    "referenceType" : "ReferenceMolecule",
    "parents" : [ ],
    "children" : [ ]
  }, {
    "dbId" : 10361357,
    "stId" : "R-BTA-5357471",
    "displayName" : "phospho-PAK3 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48898,
    "identifier" : "A0A3Q1LNA9",
    "standardIdentifier" : "uniprot:A0A3Q1LNA9",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "PAK3" ],
    "parents" : [ 10361359 ],
    "children" : [ ]
  }, {
    "dbId" : 10361353,
    "stId" : "R-BTA-399824",
    "displayName" : "phospho-p-S141,T402-PAK2 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48898,
    "identifier" : "A0A3Q1M0G8",
    "standardIdentifier" : "uniprot:A0A3Q1M0G8",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 10398051, 10361359 ],
    "children" : [ ]
  }, {
    "dbId" : 10361349,
    "stId" : "R-BTA-399819",
    "displayName" : "phospho-p-S144,T423-PAK1 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48898,
    "identifier" : "Q08E52",
    "standardIdentifier" : "uniprot:Q08E52",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 10361359 ],
    "children" : [ ]
  }, {
    "dbId" : 10348033,
    "stId" : "R-BTA-186833",
    "displayName" : "RASA1 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48898,
    "diagramIds" : [ 97514 ],
    "identifier" : "F1N7N8",
    "standardIdentifier" : "uniprot:F1N7N8",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "RASA1" ],
    "parents" : [ 10398157 ],
    "children" : [ ]
  }, {
    "dbId" : 10341432,
    "stId" : "R-BTA-5665993",
    "displayName" : "RHOA:GTP [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 48898,
    "diagramIds" : [ 97325 ],
    "parents" : [ 10394960 ],
    "children" : [ 29438, 10341428 ]
  }, {
    "dbId" : 10341428,
    "stId" : "R-BTA-194510",
    "displayName" : "RHOA [plasma membrane]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48898,
    "identifier" : "P61585",
    "standardIdentifier" : "uniprot:P61585",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 10341432 ],
    "children" : [ ]
  }, {
    "dbId" : 10346033,
    "stId" : "R-BTA-109783",
    "displayName" : "p21 RAS:GTP [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 48898,
    "diagramIds" : [ 97516 ],
    "parents" : [ 10398157 ],
    "children" : [ 10346031, 29438 ]
  }, {
    "dbId" : 29356,
    "stId" : "R-ALL-29356",
    "displayName" : "H2O [cytosol]",
    "schemaClass" : "SimpleEntity",
    "speciesId" : 0,
    "diagramIds" : [ 97433 ],
    "identifier" : "15377",
    "standardIdentifier" : "chebi:15377",
    "referenceType" : "ReferenceMolecule",
    "parents" : [ ],
    "children" : [ ]
  }, {
    "dbId" : 29870,
    "stId" : "R-ALL-29870",
    "displayName" : "BH4 [cytosol]",
    "schemaClass" : "SimpleEntity",
    "speciesId" : 0,
    "diagramIds" : [ 97423 ],
    "identifier" : "59560",
    "standardIdentifier" : "chebi:59560",
    "referenceType" : "ReferenceMolecule",
    "parents" : [ 10352243, 10352236 ],
    "children" : [ ]
  }, {
    "dbId" : 10346031,
    "stId" : "R-BTA-9649715",
    "displayName" : "mature p21 RAS [plasma membrane]",
    "schemaClass" : "DefinedSet",
    "speciesId" : 48898,
    "parents" : [ 10346033 ],
    "children" : [ 10346019, 10346026, 10346013 ]
  }, {
    "dbId" : 29364,
    "stId" : "R-ALL-29364",
    "displayName" : "NADPH [cytosol]",
    "schemaClass" : "SimpleEntity",
    "speciesId" : 0,
    "diagramIds" : [ 97426 ],
    "identifier" : "57783",
    "standardIdentifier" : "chebi:57783",
    "referenceType" : "ReferenceMolecule",
    "parents" : [ ],
    "children" : [ ]
  }, {
    "dbId" : 10354217,
    "stId" : "R-BTA-210216",
    "displayName" : "Integrin alphaVbeta3 [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 48898,
    "diagramIds" : [ 97319 ],
    "parents" : [ 10398073 ],
    "children" : [ 10354215, 10341515 ]
  }, {
    "dbId" : 29366,
    "stId" : "R-ALL-29366",
    "displayName" : "NADP+ [cytosol]",
    "schemaClass" : "SimpleEntity",
    "speciesId" : 0,
    "diagramIds" : [ 97431 ],
    "identifier" : "58349",
    "standardIdentifier" : "chebi:58349",
    "referenceType" : "ReferenceMolecule",
    "parents" : [ ],
    "children" : [ ]
  }, {
    "dbId" : 10346026,
    "stId" : "R-BTA-9647912",
    "displayName" : "S-Farn-Me-2xPalmS HRAS [plasma membrane]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48898,
    "identifier" : "G3MXH2",
    "standardIdentifier" : "uniprot:G3MXH2",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 10346031 ],
    "children" : [ ]
  }, {
    "dbId" : 10335274,
    "stId" : "R-BTA-9016707",
    "displayName" : "CALM1 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48898,
    "identifier" : "A0A3Q1MR28",
    "standardIdentifier" : "uniprot:A0A3Q1MR28",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 10340783 ],
    "children" : [ ]
  }, {
    "dbId" : 29368,
    "stId" : "R-ALL-29368",
    "displayName" : "O2 [cytosol]",
    "schemaClass" : "SimpleEntity",
    "speciesId" : 0,
    "diagramIds" : [ 97428 ],
    "identifier" : "15379",
    "standardIdentifier" : "chebi:15379",
    "referenceType" : "ReferenceMolecule",
    "parents" : [ ],
    "children" : [ ]
  }, {
    "dbId" : 10399271,
    "stId" : "R-BTA-5357459",
    "displayName" : "p-S665-VE-cadherin-Catenin complex [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 48898,
    "diagramIds" : [ 97399 ],
    "parents" : [ ],
    "children" : [ 10362225, 10362211, 10399269, 10362221 ]
  }, {
    "dbId" : 29370,
    "stId" : "R-ALL-29370",
    "displayName" : "ADP [cytosol]",
    "schemaClass" : "SimpleEntity",
    "speciesId" : 0,
    "diagramIds" : [ 97345, 97473, 97479, 97351, 97419, 97487, 97296, 97303, 97495, 97499, 97373, 97311, 97379, 97317, 97509, 97449, 97387, 97515, 97452, 97520, 97394, 97332, 97463, 97400, 97468, 97340 ],
    "identifier" : "456216",
    "standardIdentifier" : "chebi:456216",
    "referenceType" : "ReferenceMolecule",
    "parents" : [ ],
    "children" : [ ]
  }, {
    "dbId" : 10354215,
    "stId" : "R-BTA-210013",
    "displayName" : "ITGAV [plasma membrane]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48898,
    "identifier" : "A0A3Q1MXS2",
    "standardIdentifier" : "uniprot:A0A3Q1MXS2",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "ITGAV" ],
    "parents" : [ 10354217 ],
    "children" : [ ]
  }, {
    "dbId" : 10399269,
    "stId" : "R-BTA-5357435",
    "displayName" : "phospho-CDH5 [plasma membrane]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48898,
    "identifier" : "G3MZL1",
    "standardIdentifier" : "uniprot:G3MZL1",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "CDH5" ],
    "parents" : [ 10399271 ],
    "children" : [ ]
  }, {
    "dbId" : 10399266,
    "stId" : "R-BTA-5357454",
    "displayName" : "VE-cadherin-Catenin complex [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 48898,
    "diagramIds" : [ 97398 ],
    "parents" : [ ],
    "children" : [ 10362225, 10362211, 10362221, 10362159 ]
  }, {
    "dbId" : 10346019,
    "stId" : "R-BTA-9647910",
    "displayName" : "NRAS [plasma membrane]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48898,
    "identifier" : "A5D7R9",
    "standardIdentifier" : "uniprot:A5D7R9",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "NRAS" ],
    "parents" : [ 10346031 ],
    "children" : [ ]
  }, {
    "dbId" : 10352221,
    "stId" : "R-BTA-534996",
    "displayName" : "HSP90AA1 [plasma membrane]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48898,
    "identifier" : "Q76LV2",
    "standardIdentifier" : "uniprot:Q76LV2",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 10352248, 10352223 ],
    "children" : [ ]
  }, {
    "dbId" : 10352223,
    "stId" : "R-BTA-202105",
    "displayName" : "eNOS:CaM:HSP90 [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 48898,
    "diagramIds" : [ 97415 ],
    "parents" : [ 10352227 ],
    "children" : [ 10352212, 10352202, 10352221 ]
  }, {
    "dbId" : 10348126,
    "stId" : "R-BTA-187743",
    "displayName" : "MAPKAPK2 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48898,
    "identifier" : "A0A3Q1M614",
    "standardIdentifier" : "uniprot:A0A3Q1M614",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 10348132 ],
    "children" : [ ]
  }, {
    "dbId" : 10345561,
    "stId" : "R-BTA-2980677",
    "displayName" : "CRK [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48898,
    "diagramIds" : [ 97355 ],
    "identifier" : "E1BQ32",
    "standardIdentifier" : "uniprot:E1BQ32",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "CRK" ],
    "parents" : [ 10398045, 10387938 ],
    "children" : [ ]
  }, {
    "dbId" : 10352212,
    "stId" : "R-BTA-534997",
    "displayName" : "CALM1:4Ca2+ [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 48898,
    "parents" : [ 10352214, 10352248, 10352223 ],
    "children" : [ 10352210, 140648 ]
  }, {
    "dbId" : 29386,
    "stId" : "R-ALL-29386",
    "displayName" : "FAD [cytosol]",
    "schemaClass" : "SimpleEntity",
    "speciesId" : 0,
    "identifier" : "57692",
    "standardIdentifier" : "chebi:57692",
    "referenceType" : "ReferenceMolecule",
    "parents" : [ 10398129, 10352236, 10352202 ],
    "children" : [ ]
  }, {
    "dbId" : 10352214,
    "stId" : "R-BTA-202116",
    "displayName" : "eNOS:Caveolin-1:CaM [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 48898,
    "diagramIds" : [ 97409 ],
    "parents" : [ ],
    "children" : [ 10352208, 10352212 ]
  }, {
    "dbId" : 10352208,
    "stId" : "R-BTA-202128",
    "displayName" : "eNOS:Caveolin-1 [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 48898,
    "diagramIds" : [ 97407 ],
    "parents" : [ 10352214, 10352248 ],
    "children" : [ 10352202, 10352206 ]
  }, {
    "dbId" : 10352210,
    "stId" : "R-BTA-9016884",
    "displayName" : "CALM1 [plasma membrane]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48898,
    "identifier" : "A0A3Q1MR28",
    "standardIdentifier" : "uniprot:A0A3Q1MR28",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 10352212 ],
    "children" : [ ]
  }, {
    "dbId" : 10352206,
    "stId" : "R-BTA-534994",
    "displayName" : "CAV1 [plasma membrane]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48898,
    "identifier" : "P79132",
    "standardIdentifier" : "uniprot:P79132",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "CAV1" ],
    "parents" : [ 10352208 ],
    "children" : [ ]
  }, {
    "dbId" : 10352200,
    "stId" : "R-BTA-534993",
    "displayName" : "2xPalmC-MyrG-NOS3 [plasma membrane]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48898,
    "identifier" : "A0A3Q1LSD1",
    "standardIdentifier" : "uniprot:A0A3Q1LSD1",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 10352202 ],
    "children" : [ ]
  }, {
    "dbId" : 10352202,
    "stId" : "R-BTA-203639",
    "displayName" : "palmitoylated, myristoylated eNOS dimer [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 48898,
    "parents" : [ 10352208, 10352223 ],
    "children" : [ 29386, 10352200, 73524, 29426, 71185 ]
  }, {
    "dbId" : 9679475,
    "stId" : "R-ALL-9679475",
    "displayName" : "aflibercept [extracellular region]",
    "schemaClass" : "ProteinDrug",
    "speciesId" : 0,
    "identifier" : "6786",
    "standardIdentifier" : "iuphar.ligand:6786",
    "parents" : [ 9679456 ],
    "children" : [ ]
  }, {
    "dbId" : 9679474,
    "stId" : "R-ALL-9679474",
    "displayName" : "abicipar pegol [extracellular region]",
    "schemaClass" : "ProteinDrug",
    "speciesId" : 0,
    "identifier" : "8371",
    "standardIdentifier" : "iuphar.ligand:8371",
    "parents" : [ 9679456 ],
    "children" : [ ]
  }, {
    "dbId" : 10352248,
    "stId" : "R-BTA-202130",
    "displayName" : "eNOS:Caveolin-1:CaM:HSP90 [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 48898,
    "diagramIds" : [ 97412 ],
    "parents" : [ ],
    "children" : [ 10352208, 10352212, 10352221 ]
  }, {
    "dbId" : 10360443,
    "stId" : "R-BTA-195066",
    "displayName" : "VAV1 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48898,
    "identifier" : "Q08DN7",
    "standardIdentifier" : "uniprot:Q08DN7",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "VAV1" ],
    "parents" : [ 10364292 ],
    "children" : [ ]
  }, {
    "dbId" : 29926,
    "stId" : "R-ALL-29926",
    "displayName" : "Mg2+ [cytosol]",
    "schemaClass" : "SimpleEntity",
    "speciesId" : 0,
    "identifier" : "18420",
    "standardIdentifier" : "chebi:18420",
    "referenceType" : "ReferenceMolecule",
    "parents" : [ 10348151, 10397953, 10394883 ],
    "children" : [ ]
  }, {
    "dbId" : 10348149,
    "stId" : "R-BTA-170997",
    "displayName" : "p-p38 MAPK alpha/beta [cytosol]",
    "schemaClass" : "DefinedSet",
    "speciesId" : 48898,
    "parents" : [ 10348151 ],
    "children" : [ 10348147, 10348145 ]
  }, {
    "dbId" : 9679482,
    "stId" : "R-ALL-9679482",
    "displayName" : "brolucizumab [extracellular region]",
    "schemaClass" : "ProteinDrug",
    "speciesId" : 0,
    "identifier" : "8713",
    "standardIdentifier" : "iuphar.ligand:8713",
    "parents" : [ 9679456 ],
    "children" : [ ]
  }, {
    "dbId" : 10348151,
    "stId" : "R-BTA-170993",
    "displayName" : "Phospho-MAP kinase p38 (Mg2+ cofactor) [cytosol]",
    "schemaClass" : "Complex",
    "speciesId" : 48898,
    "diagramIds" : [ 97472 ],
    "parents" : [ ],
    "children" : [ 10348149, 29926 ]
  }, {
    "dbId" : 10348145,
    "stId" : "R-BTA-171009",
    "displayName" : "phospho-p-T180,Y182-MAPK11 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48898,
    "identifier" : "G3X793",
    "standardIdentifier" : "uniprot:G3X793",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 10348149 ],
    "children" : [ ]
  }, {
    "dbId" : 10341491,
    "stId" : "R-BTA-58198",
    "displayName" : "PRKCB [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48898,
    "identifier" : "P05126",
    "standardIdentifier" : "uniprot:P05126",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "PRKCB", "PRKCB1" ],
    "parents" : [ 10398100 ],
    "children" : [ ]
  }, {
    "dbId" : 10352243,
    "stId" : "R-BTA-1497830",
    "displayName" : "p-S1177-eNOS:CaM:HSP90:p-AKT1:BH4 [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 48898,
    "diagramIds" : [ 97424 ],
    "parents" : [ ],
    "children" : [ 29870, 10352238 ]
  }, {
    "dbId" : 10348147,
    "stId" : "R-BTA-428935",
    "displayName" : "phospho-p-T180,Y182-MAPK14 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48898,
    "identifier" : "A0A3Q1LTT9",
    "standardIdentifier" : "uniprot:A0A3Q1LTT9",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 10348149 ],
    "children" : [ ]
  }, {
    "dbId" : 10348141,
    "stId" : "R-BTA-187723",
    "displayName" : "phospho-p-S,2T-MAPKAPK3 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48898,
    "identifier" : "Q3SYZ2",
    "standardIdentifier" : "uniprot:Q3SYZ2",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 10348143 ],
    "children" : [ ]
  }, {
    "dbId" : 9679458,
    "stId" : "R-ALL-9679458",
    "displayName" : "bevacizumab [extracellular region]",
    "schemaClass" : "ProteinDrug",
    "speciesId" : 0,
    "identifier" : "6771",
    "standardIdentifier" : "iuphar.ligand:6771",
    "parents" : [ 9679456 ],
    "children" : [ ]
  }, {
    "dbId" : 10352236,
    "stId" : "R-BTA-203564",
    "displayName" : "p-S1177-eNOS dimer [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 48898,
    "parents" : [ 10352238 ],
    "children" : [ 29870, 29386, 10352234, 73524, 29426, 71185 ]
  }, {
    "dbId" : 29426,
    "stId" : "R-ALL-29426",
    "displayName" : "Zn2+ [cytosol]",
    "schemaClass" : "SimpleEntity",
    "speciesId" : 0,
    "identifier" : "29105",
    "standardIdentifier" : "chebi:29105",
    "referenceType" : "ReferenceMolecule",
    "parents" : [ 10352236, 10352202 ],
    "children" : [ ]
  }, {
    "dbId" : 10348143,
    "stId" : "R-BTA-187726",
    "displayName" : "p-S272,T222,T334-MAPKAPK2, p-S,2T-MAPKAPK3 [cytosol]",
    "schemaClass" : "DefinedSet",
    "speciesId" : 48898,
    "diagramIds" : [ 97480 ],
    "parents" : [ ],
    "children" : [ 10348137, 10348141 ]
  }, {
    "dbId" : 9679456,
    "stId" : "R-ALL-9679456",
    "displayName" : "VEGFA inhibitors [extracellular region]",
    "schemaClass" : "CandidateSet",
    "speciesId" : 0,
    "diagramIds" : [ 97525 ],
    "parents" : [ 10433984 ],
    "children" : [ 9679464, 9679482, 9679463, 9679458, 9679475, 9679469, 9679474 ]
  }, {
    "dbId" : 10352238,
    "stId" : "R-BTA-202121",
    "displayName" : "p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 48898,
    "diagramIds" : [ 97420 ],
    "parents" : [ 10352243 ],
    "children" : [ 10352231, 10352229, 10340783, 10352236 ]
  }, {
    "dbId" : 9679463,
    "stId" : "R-ALL-9679463",
    "displayName" : "pegaptanib [extracellular region]",
    "schemaClass" : "ChemicalDrug",
    "speciesId" : 0,
    "identifier" : "6836",
    "standardIdentifier" : "iuphar.ligand:6836",
    "parents" : [ 9679456 ],
    "children" : [ ]
  }, {
    "dbId" : 10348137,
    "stId" : "R-BTA-187760",
    "displayName" : "phospho-p-S272,T222,T334-MAPKAPK2 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48898,
    "identifier" : "A0A3Q1M614",
    "standardIdentifier" : "uniprot:A0A3Q1M614",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 10348143 ],
    "children" : [ ]
  }, {
    "dbId" : 10352234,
    "stId" : "R-BTA-202139",
    "displayName" : "phospho-2xPalmC-MyrG-p-S1177-NOS3 [plasma membrane]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48898,
    "identifier" : "A0A3Q1LSD1",
    "standardIdentifier" : "uniprot:A0A3Q1LSD1",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 10352236 ],
    "children" : [ ]
  }, {
    "dbId" : 10352229,
    "stId" : "R-BTA-192864",
    "displayName" : "HSP90AA1 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48898,
    "diagramIds" : [ 97411, 97322 ],
    "identifier" : "Q76LV2",
    "standardIdentifier" : "uniprot:Q76LV2",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 10352238, 10395298, 10398118, 10398012 ],
    "children" : [ ]
  }, {
    "dbId" : 10348132,
    "stId" : "R-BTA-187699",
    "displayName" : "MAPKAP kinase [cytosol]",
    "schemaClass" : "DefinedSet",
    "speciesId" : 48898,
    "diagramIds" : [ 97518 ],
    "parents" : [ ],
    "children" : [ 10348130, 10348126 ]
  }, {
    "dbId" : 10352231,
    "stId" : "R-BTA-198356",
    "displayName" : "Ghost homologue of p-T308,S473-AKT1 [cytosol]",
    "schemaClass" : "GenomeEncodedEntity",
    "speciesId" : 48898,
    "parents" : [ 10352238 ],
    "children" : [ ]
  }, {
    "dbId" : 9679464,
    "stId" : "R-ALL-9679464",
    "displayName" : "ranibizumab [extracellular region]",
    "schemaClass" : "ProteinDrug",
    "speciesId" : 0,
    "identifier" : "6779",
    "standardIdentifier" : "iuphar.ligand:6779",
    "parents" : [ 9679456 ],
    "children" : [ ]
  }, {
    "dbId" : 10352225,
    "stId" : "R-BTA-199430",
    "displayName" : "Ghost homologue of p-T308,S473-AKT1 [plasma membrane]",
    "schemaClass" : "GenomeEncodedEntity",
    "speciesId" : 48898,
    "parents" : [ 10352227 ],
    "children" : [ ]
  }, {
    "dbId" : 29438,
    "stId" : "R-ALL-29438",
    "displayName" : "GTP [cytosol]",
    "schemaClass" : "SimpleEntity",
    "speciesId" : 0,
    "identifier" : "37565",
    "standardIdentifier" : "chebi:37565",
    "referenceType" : "ReferenceMolecule",
    "parents" : [ 10394883, 10347838, 10341432, 10346033, 10361303 ],
    "children" : [ ]
  }, {
    "dbId" : 9679469,
    "stId" : "R-ALL-9679469",
    "displayName" : "vanucizumab [extracellular region]",
    "schemaClass" : "ProteinDrug",
    "speciesId" : 0,
    "identifier" : "9132",
    "standardIdentifier" : "iuphar.ligand:9132",
    "parents" : [ 9679456 ],
    "children" : [ ]
  }, {
    "dbId" : 10352227,
    "stId" : "R-BTA-202113",
    "displayName" : "eNOS:CaM:HSP90:p-AKT1 [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 48898,
    "diagramIds" : [ 97418 ],
    "parents" : [ ],
    "children" : [ 10352225, 10352223 ]
  }, {
    "dbId" : 10348130,
    "stId" : "R-BTA-187764",
    "displayName" : "MAPKAPK3 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48898,
    "identifier" : "Q3SYZ2",
    "standardIdentifier" : "uniprot:Q3SYZ2",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 10348132 ],
    "children" : [ ]
  }, {
    "dbId" : 10363806,
    "stId" : "R-BTA-428933",
    "displayName" : "MAPK14 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48898,
    "identifier" : "A0A3Q1LTT9",
    "standardIdentifier" : "uniprot:A0A3Q1LTT9",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 10397951 ],
    "children" : [ ]
  }, {
    "dbId" : 10396063,
    "stId" : "R-BTA-4420171",
    "displayName" : "VEGFA:p-6Y-VEGFR2:SHC2 [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 48898,
    "diagramIds" : [ 97363 ],
    "parents" : [ ],
    "children" : [ 10395283, 10396061 ]
  }, {
    "dbId" : 10337695,
    "stId" : "R-BTA-74789",
    "displayName" : "PIK3R1 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48898,
    "identifier" : "P23727",
    "standardIdentifier" : "uniprot:P23727",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "PIK3R1" ],
    "parents" : [ 10337701 ],
    "children" : [ ]
  }, {
    "dbId" : 10396061,
    "stId" : "R-BTA-167050",
    "displayName" : "SHC2 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48898,
    "diagramIds" : [ 97361 ],
    "identifier" : "F1N5N3",
    "standardIdentifier" : "uniprot:F1N5N3",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "SHC2" ],
    "parents" : [ 10396063 ],
    "children" : [ ]
  }, {
    "dbId" : 10398107,
    "stId" : "R-BTA-5218716",
    "displayName" : "phospho-SPHK1 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48898,
    "diagramIds" : [ 97508 ],
    "identifier" : "F1MXZ6",
    "standardIdentifier" : "uniprot:F1MXZ6",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "SPHK1" ],
    "parents" : [ ],
    "children" : [ ]
  }, {
    "dbId" : 10362263,
    "stId" : "R-BTA-419057",
    "displayName" : "ROCK1,ROCK2 [cytosol]",
    "schemaClass" : "DefinedSet",
    "speciesId" : 48898,
    "diagramIds" : [ 97326 ],
    "parents" : [ 10394960, 10398120 ],
    "children" : [ 10351874, 10362261 ]
  }, {
    "dbId" : 10396055,
    "stId" : "R-BTA-4420196",
    "displayName" : "VEGFA dimer:p-6Y-VEGFR2 dimer:SHB [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 48898,
    "diagramIds" : [ 97299 ],
    "parents" : [ ],
    "children" : [ 10395283, 10396053 ]
  }, {
    "dbId" : 10398100,
    "stId" : "R-BTA-5218761",
    "displayName" : "PKCA,PKCB,PKCD,PKCZ [cytosol]",
    "schemaClass" : "DefinedSet",
    "speciesId" : 48898,
    "diagramIds" : [ 97493 ],
    "parents" : [ ],
    "children" : [ 10341491, 10398098, 10340843 ]
  }, {
    "dbId" : 10362261,
    "stId" : "R-BTA-419058",
    "displayName" : "ROCK2 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48898,
    "identifier" : "A0A3Q1MW77",
    "standardIdentifier" : "uniprot:A0A3Q1MW77",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 10362263 ],
    "children" : [ ]
  }, {
    "dbId" : 10396053,
    "stId" : "R-BTA-4420213",
    "displayName" : "SHB [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48898,
    "diagramIds" : [ 97298 ],
    "identifier" : "E1BLY9",
    "standardIdentifier" : "uniprot:E1BLY9",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "SHB" ],
    "parents" : [ 10396055 ],
    "children" : [ ]
  }, {
    "dbId" : 10398098,
    "stId" : "R-BTA-58218",
    "displayName" : "PRKCZ [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48898,
    "identifier" : "A0JNH7",
    "standardIdentifier" : "uniprot:A0JNH7",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 10398100 ],
    "children" : [ ]
  }, {
    "dbId" : 10396049,
    "stId" : "R-BTA-4420141",
    "displayName" : "VEGFA:p-6Y-VEGFR2:p-SHB:PTK2 [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 48898,
    "diagramIds" : [ 97307 ],
    "parents" : [ ],
    "children" : [ 10351927, 10395290 ]
  }, {
    "dbId" : 29968,
    "stId" : "R-ALL-29968",
    "displayName" : "L-Cit [cytosol]",
    "schemaClass" : "SimpleEntity",
    "speciesId" : 0,
    "diagramIds" : [ 97432 ],
    "identifier" : "57743",
    "standardIdentifier" : "chebi:57743",
    "referenceType" : "ReferenceMolecule",
    "parents" : [ ],
    "children" : [ ]
  }, {
    "dbId" : 10398094,
    "stId" : "R-BTA-5218789",
    "displayName" : "p-VAV family:PIP3 [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 48898,
    "diagramIds" : [ 97393 ],
    "parents" : [ ],
    "children" : [ 179838, 10385143 ]
  }, {
    "dbId" : 10398089,
    "stId" : "R-BTA-5357488",
    "displayName" : "VEGFA dimer:p-6Y-VEGFR2 dimer:PI3K/VEGFA:p-6Y-VEGFR2:SH2D2A:p-Y418-SRC-1:p-Y772,Y814-AXL:PI3K [plasma membrane]",
    "schemaClass" : "DefinedSet",
    "speciesId" : 48898,
    "diagramIds" : [ 97389 ],
    "parents" : [ ],
    "children" : [ 10398087, 10398077 ]
  }, {
    "dbId" : 10398087,
    "stId" : "R-BTA-5357453",
    "displayName" : "VEGFA:p-6Y-VEGFR2:SH2D2A:p-Y418-SRC-1:p-Y779,Y821-AXL:PI3K [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 48898,
    "diagramIds" : [ 97383 ],
    "parents" : [ 10398089 ],
    "children" : [ 10337713, 10398085 ]
  }, {
    "dbId" : 10364292,
    "stId" : "R-BTA-430172",
    "displayName" : "VAV1,2,3 [cytosol]",
    "schemaClass" : "DefinedSet",
    "speciesId" : 48898,
    "parents" : [ 10364856 ],
    "children" : [ 10360443, 10362282, 10362286 ]
  }, {
    "dbId" : 10398085,
    "stId" : "R-BTA-5357462",
    "displayName" : "VEGFA:p-6Y-VEGFR2:SH2D2A:p-Y418-SRC-1:p-Y779,Y821-AXL [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 48898,
    "diagramIds" : [ 97380 ],
    "parents" : [ 10398087 ],
    "children" : [ 10396096, 10398083 ]
  }, {
    "dbId" : 29468,
    "stId" : "R-ALL-29468",
    "displayName" : "L-Arg [cytosol]",
    "schemaClass" : "SimpleEntity",
    "speciesId" : 0,
    "diagramIds" : [ 97427 ],
    "identifier" : "32682",
    "standardIdentifier" : "chebi:32682",
    "referenceType" : "ReferenceMolecule",
    "parents" : [ ],
    "children" : [ ]
  }, {
    "dbId" : 10398083,
    "stId" : "R-BTA-5357460",
    "displayName" : "phospho-p-Y779,Y821-AXL [plasma membrane]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48898,
    "identifier" : "A0A3Q1MRN2",
    "standardIdentifier" : "uniprot:A0A3Q1MRN2",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 10398085 ],
    "children" : [ ]
  }, {
    "dbId" : 74016,
    "stId" : "R-ALL-74016",
    "displayName" : "Ca2+ [cytosol]",
    "schemaClass" : "SimpleEntity",
    "speciesId" : 0,
    "diagramIds" : [ 97503 ],
    "identifier" : "29108",
    "standardIdentifier" : "chebi:29108",
    "referenceType" : "ReferenceMolecule",
    "parents" : [ 10398060, 10340783 ],
    "children" : [ ]
  }, {
    "dbId" : 10375103,
    "stId" : "R-BTA-1222296",
    "displayName" : "NCF1 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48898,
    "identifier" : "A0A452DHY1",
    "standardIdentifier" : "uniprot:A0A452DHY1",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "NCF1" ],
    "parents" : [ 10398131 ],
    "children" : [ ]
  }, {
    "dbId" : 10398140,
    "stId" : "R-BTA-5218778",
    "displayName" : "VEGFA:p-6Y-VEGFR2:Integrin alphaVbeta3:p-Y402-PTK2B [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 48898,
    "diagramIds" : [ 97339 ],
    "parents" : [ ],
    "children" : [ 10398073, 10398138 ]
  }, {
    "dbId" : 10398138,
    "stId" : "R-BTA-5218721",
    "displayName" : "phospho-PTK2B [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48898,
    "identifier" : "A0A3Q1LVP1",
    "standardIdentifier" : "uniprot:A0A3Q1LVP1",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 10398140 ],
    "children" : [ ]
  }, {
    "dbId" : 10364856,
    "stId" : "R-BTA-5340329",
    "displayName" : "PIP3:VAV1,2,3 [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 48898,
    "diagramIds" : [ 97391 ],
    "parents" : [ ],
    "children" : [ 179838, 10364292 ]
  }, {
    "dbId" : 10396086,
    "stId" : "R-BTA-4420169",
    "displayName" : "VEGFA dimer:p-6Y-VEGFR2 dimer:SH2D2A:SRC-1 [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 48898,
    "diagramIds" : [ 97369 ],
    "parents" : [ ],
    "children" : [ 10396084, 10348836 ]
  }, {
    "dbId" : 10398135,
    "stId" : "R-BTA-5218787",
    "displayName" : "VEGFA:p-6Y-VEGFR2:Integrin alphaVbeta3:PTK2B [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 48898,
    "diagramIds" : [ 97336 ],
    "parents" : [ ],
    "children" : [ 10360976, 10398073 ]
  }, {
    "dbId" : 10396084,
    "stId" : "R-BTA-4420137",
    "displayName" : "VEGFA dimer:p-6Y-VEGFR2 dimer:SH2D2A [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 48898,
    "diagramIds" : [ 97366 ],
    "parents" : [ 10396086, 10396096 ],
    "children" : [ 10395283, 10396082 ]
  }, {
    "dbId" : 10396082,
    "stId" : "R-BTA-4420125",
    "displayName" : "SH2D2A [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48898,
    "diagramIds" : [ 97365 ],
    "identifier" : "A7Z041",
    "standardIdentifier" : "uniprot:A7Z041",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "SH2D2A" ],
    "parents" : [ 10396084 ],
    "children" : [ ]
  }, {
    "dbId" : 10337713,
    "stId" : "R-BTA-74693",
    "displayName" : "PI3K [cytosol]",
    "schemaClass" : "Complex",
    "speciesId" : 48898,
    "diagramIds" : [ 97382 ],
    "parents" : [ 10398087, 10398077 ],
    "children" : [ 10337701, 10337711 ]
  }, {
    "dbId" : 10398131,
    "stId" : "R-BTA-5218791",
    "displayName" : "NOX2 complex [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 48898,
    "parents" : [ 10398152 ],
    "children" : [ 10398129, 10375107, 10375111, 10375103 ]
  }, {
    "dbId" : 10364336,
    "stId" : "R-BTA-201877",
    "displayName" : "F-actin [cytosol]",
    "schemaClass" : "Polymer",
    "speciesId" : 48898,
    "diagramIds" : [ 97477 ],
    "parents" : [ 10398187 ],
    "children" : [ 10352952 ]
  }, {
    "dbId" : 10352562,
    "stId" : "R-BTA-167679",
    "displayName" : "phospho-p-4Y-PLCG1 [plasma membrane]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48898,
    "diagramIds" : [ 97490 ],
    "identifier" : "F1MYF9",
    "standardIdentifier" : "uniprot:F1MYF9",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 10396074 ],
    "children" : [ ]
  }, {
    "dbId" : 10398129,
    "stId" : "R-BTA-5218783",
    "displayName" : "Cytochrome b-245 [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 48898,
    "parents" : [ 10398131 ],
    "children" : [ 29386, 10398125, 10398127, 71185 ]
  }, {
    "dbId" : 10364849,
    "stId" : "R-BTA-437946",
    "displayName" : "phospho-VAV1 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48898,
    "identifier" : "Q08DN7",
    "standardIdentifier" : "uniprot:Q08DN7",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "VAV1" ],
    "parents" : [ 10385143 ],
    "children" : [ ]
  }, {
    "dbId" : 10337709,
    "stId" : "R-BTA-74788",
    "displayName" : "PIK3CB [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48898,
    "identifier" : "F1MYM3",
    "standardIdentifier" : "uniprot:F1MYM3",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "PIK3CB" ],
    "parents" : [ 10337711 ],
    "children" : [ ]
  }, {
    "dbId" : 10362286,
    "stId" : "R-BTA-430152",
    "displayName" : "VAV3 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48898,
    "identifier" : "E1BBD2",
    "standardIdentifier" : "uniprot:E1BBD2",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "VAV3" ],
    "parents" : [ 10364292 ],
    "children" : [ ]
  }, {
    "dbId" : 10398127,
    "stId" : "R-BTA-5218720",
    "displayName" : "CYBB [plasma membrane]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48898,
    "identifier" : "O46522",
    "standardIdentifier" : "uniprot:O46522",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 10398129 ],
    "children" : [ ]
  }, {
    "dbId" : 10340783,
    "stId" : "R-BTA-74294",
    "displayName" : "CALM1:4xCa2+ [cytosol]",
    "schemaClass" : "Complex",
    "speciesId" : 48898,
    "diagramIds" : [ 97408 ],
    "parents" : [ 10352238 ],
    "children" : [ 10335274, 74016 ]
  }, {
    "dbId" : 10337711,
    "stId" : "R-BTA-74689",
    "displayName" : "PI3K-catalytic subunit [cytosol]",
    "schemaClass" : "DefinedSet",
    "speciesId" : 48898,
    "parents" : [ 10337713 ],
    "children" : [ 10337705, 10337709 ]
  }, {
    "dbId" : 10398125,
    "stId" : "R-BTA-5218744",
    "displayName" : "CYBA [plasma membrane]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48898,
    "identifier" : "O46521",
    "standardIdentifier" : "uniprot:O46521",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "CYBA" ],
    "parents" : [ 10398129 ],
    "children" : [ ]
  }, {
    "dbId" : 10396074,
    "stId" : "R-BTA-4420110",
    "displayName" : "VEGFA dimer:p-6Y-VEGFR2 dimer:p-4Y-PLCG1 [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 48898,
    "diagramIds" : [ 97486 ],
    "parents" : [ ],
    "children" : [ 10352562, 10395283 ]
  }, {
    "dbId" : 10337705,
    "stId" : "R-BTA-74787",
    "displayName" : "PIK3CA [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48898,
    "identifier" : "P32871",
    "standardIdentifier" : "uniprot:P32871",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "PIK3CA" ],
    "parents" : [ 10337711 ],
    "children" : [ ]
  }, {
    "dbId" : 10362282,
    "stId" : "R-BTA-195012",
    "displayName" : "VAV2 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48898,
    "identifier" : "A0A3Q1MQP9",
    "standardIdentifier" : "uniprot:A0A3Q1MQP9",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "VAV2" ],
    "parents" : [ 10364292 ],
    "children" : [ ]
  }, {
    "dbId" : 73524,
    "stId" : "R-ALL-73524",
    "displayName" : "FMN [cytosol]",
    "schemaClass" : "SimpleEntity",
    "speciesId" : 0,
    "identifier" : "58210",
    "standardIdentifier" : "chebi:58210",
    "referenceType" : "ReferenceMolecule",
    "parents" : [ 10352236, 10352202 ],
    "children" : [ ]
  }, {
    "dbId" : 10396072,
    "stId" : "R-BTA-4420203",
    "displayName" : "VEGFA dimer:p-6Y-VEGFR2 dimer:PLCG1 [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 48898,
    "diagramIds" : [ 97483 ],
    "parents" : [ ],
    "children" : [ 10395283, 10352417 ]
  }, {
    "dbId" : 10398120,
    "stId" : "R-BTA-5228987",
    "displayName" : "RHOA:GTP:Mg2+:Activated ROCK1,ROCK2 [cytosol]",
    "schemaClass" : "Complex",
    "speciesId" : 48898,
    "diagramIds" : [ 97329 ],
    "parents" : [ ],
    "children" : [ 10394883, 10362263 ]
  }, {
    "dbId" : 10364841,
    "stId" : "R-BTA-194866",
    "displayName" : "RHOA [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48898,
    "identifier" : "P61585",
    "standardIdentifier" : "uniprot:P61585",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 10394883 ],
    "children" : [ ]
  }, {
    "dbId" : 10398118,
    "stId" : "R-BTA-5218775",
    "displayName" : "VEGFA:p-6Y-VEGFR2:pS-SHB:p-5Y,S732-PTK2:SRC-1:HSP90AA1 [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 48898,
    "diagramIds" : [ 97333 ],
    "parents" : [ ],
    "children" : [ 10398116, 10348836, 10352229 ]
  }, {
    "dbId" : 10337701,
    "stId" : "R-BTA-74688",
    "displayName" : "PI3K-regulatory subunit [cytosol]",
    "schemaClass" : "DefinedSet",
    "speciesId" : 48898,
    "parents" : [ 10337713 ],
    "children" : [ 10337699, 10337695 ]
  }, {
    "dbId" : 10398116,
    "stId" : "R-BTA-5218771",
    "displayName" : "VEGFA:p-6Y-VEGFR2:pS-SHB:p-5Y,S732-PTK2 [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 48898,
    "parents" : [ 10398118 ],
    "children" : [ 10398114, 10395290 ]
  }, {
    "dbId" : 10398114,
    "stId" : "R-BTA-5229006",
    "displayName" : "phospho-p-5Y,S732-PTK2 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48898,
    "identifier" : "A0A3Q1MAA1",
    "standardIdentifier" : "uniprot:A0A3Q1MAA1",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 10398116 ],
    "children" : [ ]
  }, {
    "dbId" : 10446242,
    "stId" : "R-BTA-9833482",
    "displayName" : "PKR-mediated signaling",
    "schemaClass" : "Pathway",
    "speciesId" : 48898,
    "diagramIds" : [ 97567 ]
  }, {
    "dbId" : 10396067,
    "stId" : "R-BTA-195402",
    "displayName" : "VEGFA-165 dimer:VEGFR2 [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 48898,
    "diagramIds" : [ 97293 ],
    "parents" : [ ],
    "children" : [ 10395271, 10349738 ]
  }, {
    "dbId" : 10337699,
    "stId" : "R-BTA-74791",
    "displayName" : "PIK3R2 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48898,
    "identifier" : "P23726",
    "standardIdentifier" : "uniprot:P23726",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "PIK3R2" ],
    "parents" : [ 10337701 ],
    "children" : [ ]
  }, {
    "dbId" : 10387934,
    "stId" : "R-BTA-372642",
    "displayName" : "ELMO2 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48898,
    "identifier" : "A0A3Q1NMX4",
    "standardIdentifier" : "uniprot:A0A3Q1NMX4",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "ELMO2" ],
    "parents" : [ 10387936 ],
    "children" : [ ]
  }, {
    "dbId" : 10387930,
    "stId" : "R-BTA-200932",
    "displayName" : "ELMO1 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48898,
    "identifier" : "F1MQH0",
    "standardIdentifier" : "uniprot:F1MQH0",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "ELMO1" ],
    "parents" : [ 10387936 ],
    "children" : [ ]
  }, {
    "dbId" : 10361303,
    "stId" : "R-BTA-442641",
    "displayName" : "RAC1:GTP [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 48898,
    "parents" : [ 10398152 ],
    "children" : [ 29438, 10361301 ]
  }, {
    "dbId" : 10398167,
    "stId" : "R-BTA-425833",
    "displayName" : "Protein kinase A catalytic subunit [cytosol]",
    "schemaClass" : "CandidateSet",
    "speciesId" : 48898,
    "diagramIds" : [ 97454 ],
    "parents" : [ ],
    "children" : [ 10340732 ]
  }, {
    "dbId" : 10361301,
    "stId" : "R-BTA-351141",
    "displayName" : "Ghost homologue of RAC1 [plasma membrane]",
    "schemaClass" : "GenomeEncodedEntity",
    "speciesId" : 48898,
    "parents" : [ 10361303 ],
    "children" : [ ]
  }, {
    "dbId" : 10364881,
    "stId" : "R-BTA-442287",
    "displayName" : "phospho-VAV3 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48898,
    "identifier" : "E1BBD2",
    "standardIdentifier" : "uniprot:E1BBD2",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "VAV3" ],
    "parents" : [ 10385143 ],
    "children" : [ ]
  }, {
    "dbId" : 10398157,
    "stId" : "R-BTA-5218802",
    "displayName" : "RASA1:p21 RAS:GTP:SPG [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 48898,
    "diagramIds" : [ 97512 ],
    "parents" : [ ],
    "children" : [ 10346033, 10348033, 1606609 ]
  }, {
    "dbId" : 3299686,
    "stId" : "R-ALL-3299686",
    "displayName" : "O2.- [extracellular region]",
    "schemaClass" : "SimpleEntity",
    "speciesId" : 0,
    "diagramIds" : [ 97437 ],
    "identifier" : "18421",
    "standardIdentifier" : "chebi:18421",
    "referenceType" : "ReferenceMolecule",
    "parents" : [ ],
    "children" : [ ]
  }, {
    "dbId" : 10398152,
    "stId" : "R-BTA-5218774",
    "displayName" : "NOX2 complex:RAC1:GTP [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 48898,
    "diagramIds" : [ 97439 ],
    "parents" : [ ],
    "children" : [ 10398131, 10361303 ]
  }, {
    "dbId" : 10375111,
    "stId" : "R-BTA-1222707",
    "displayName" : "NCF4 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48898,
    "identifier" : "A0A3Q1MKI4",
    "standardIdentifier" : "uniprot:A0A3Q1MKI4",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 10398131 ],
    "children" : [ ]
  }, {
    "dbId" : 10356165,
    "stId" : "R-BTA-354068",
    "displayName" : "phospho-p-Y397-PTK2 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48898,
    "identifier" : "A0A3Q1MAA1",
    "standardIdentifier" : "uniprot:A0A3Q1MAA1",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 10397937 ],
    "children" : [ ]
  }, {
    "dbId" : 10364869,
    "stId" : "R-BTA-442307",
    "displayName" : "phospho-VAV2 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48898,
    "identifier" : "A0A3Q1MQP9",
    "standardIdentifier" : "uniprot:A0A3Q1MQP9",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "VAV2" ],
    "parents" : [ 10385143 ],
    "children" : [ ]
  }, {
    "dbId" : 10375107,
    "stId" : "R-BTA-1222600",
    "displayName" : "NCF2 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48898,
    "identifier" : "A0A3Q1MTW8",
    "standardIdentifier" : "uniprot:A0A3Q1MTW8",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "NCF2" ],
    "parents" : [ 10398131 ],
    "children" : [ ]
  }, {
    "dbId" : 10396096,
    "stId" : "R-BTA-5218788",
    "displayName" : "VEGFA:p-6Y-VEGFR2:SH2D2A:p-Y418-SRC-1 [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 48898,
    "diagramIds" : [ 97372 ],
    "parents" : [ 10399259, 10398085 ],
    "children" : [ 10356195, 10396084 ]
  }, {
    "dbId" : 10398144,
    "stId" : "R-BTA-5218766",
    "displayName" : "VEGFA dimer:p-6Y-VEGFR2 dimer:NCK1,NCK2:p-S21,Y420-FYN:PAK2 [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 48898,
    "diagramIds" : [ 97457 ],
    "parents" : [ ],
    "children" : [ 10360583, 10397960 ]
  }, {
    "dbId" : 10433984,
    "stId" : "R-BTA-9679453",
    "displayName" : "VEGFA-165 dimer:VEGFA inhibitors [extracellular region]",
    "schemaClass" : "Complex",
    "speciesId" : 48898,
    "diagramIds" : [ 97523 ],
    "parents" : [ ],
    "children" : [ 10395271, 9679456 ]
  }, {
    "dbId" : 140648,
    "stId" : "R-ALL-140648",
    "displayName" : "Ca2+ [plasma membrane]",
    "schemaClass" : "SimpleEntity",
    "speciesId" : 0,
    "identifier" : "29108",
    "standardIdentifier" : "chebi:29108",
    "referenceType" : "ReferenceMolecule",
    "parents" : [ 10352212 ],
    "children" : [ ]
  }, {
    "dbId" : 10398192,
    "stId" : "R-BTA-5218697",
    "displayName" : "phospho-HSPB1 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48898,
    "diagramIds" : [ 97478 ],
    "identifier" : "Q3T149",
    "standardIdentifier" : "uniprot:Q3T149",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "HSPB1" ],
    "parents" : [ ],
    "children" : [ ]
  }, {
    "dbId" : 10398187,
    "stId" : "R-BTA-5218769",
    "displayName" : "HSP27 oligomer:F-actin [cytosol]",
    "schemaClass" : "Complex",
    "speciesId" : 48898,
    "diagramIds" : [ 97476 ],
    "parents" : [ ],
    "children" : [ 10364336, 10398185 ]
  }, {
    "dbId" : 10340843,
    "stId" : "R-BTA-58200",
    "displayName" : "PRKCD [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48898,
    "identifier" : "F1MZX0",
    "standardIdentifier" : "uniprot:F1MZX0",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 10398100 ],
    "children" : [ ]
  }, {
    "dbId" : 10398185,
    "stId" : "R-BTA-5218689",
    "displayName" : "HSBP1 oligomer [cytosol]",
    "schemaClass" : "Polymer",
    "speciesId" : 48898,
    "parents" : [ 10398187 ],
    "children" : [ 10366657 ]
  }, {
    "dbId" : 10387938,
    "stId" : "R-BTA-2029141",
    "displayName" : "CRK:DOCK180:ELMO1,ELMO2 [cytosol]",
    "schemaClass" : "Complex",
    "speciesId" : 48898,
    "parents" : [ 10398047 ],
    "children" : [ 10387936, 10362130, 10345561 ]
  }, {
    "dbId" : 10356195,
    "stId" : "R-BTA-377592",
    "displayName" : "phospho-p-Y419-SRC [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48898,
    "identifier" : "E1BIM8",
    "standardIdentifier" : "uniprot:E1BIM8",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "SRC" ],
    "parents" : [ 10396096 ],
    "children" : [ ]
  }, {
    "dbId" : 10387936,
    "stId" : "R-BTA-372640",
    "displayName" : "ELMO1,ELMO2 [cytosol]",
    "schemaClass" : "DefinedSet",
    "speciesId" : 48898,
    "parents" : [ 10398025, 10387938 ],
    "children" : [ 10387930, 10387934 ]
  }, {
    "dbId" : 10397982,
    "stId" : "R-BTA-5218754",
    "displayName" : "p-PKCA,p-PKCB,p-PKCZ,p-PKCD [cytosol]",
    "schemaClass" : "DefinedSet",
    "speciesId" : 48898,
    "diagramIds" : [ 97494 ],
    "parents" : [ ],
    "children" : [ 10397975, 10397978, 10397980 ]
  }, {
    "dbId" : 10397980,
    "stId" : "R-BTA-5218746",
    "displayName" : "phospho-p-T507-PRKCD [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48898,
    "identifier" : "F1MZX0",
    "standardIdentifier" : "uniprot:F1MZX0",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 10397982 ],
    "children" : [ ]
  }, {
    "dbId" : 10361117,
    "stId" : "R-BTA-391821",
    "displayName" : "phospho-p-Y420-FYN [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48898,
    "identifier" : "A0JNB0",
    "standardIdentifier" : "uniprot:A0JNB0",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 10398000 ],
    "children" : [ ]
  }, {
    "dbId" : 10397978,
    "stId" : "R-BTA-5218728",
    "displayName" : "phospho-p-T500-PRKCB [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48898,
    "identifier" : "P05126",
    "standardIdentifier" : "uniprot:P05126",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "PRKCB", "PRKCB1" ],
    "parents" : [ 10397982 ],
    "children" : [ ]
  }, {
    "dbId" : 10397975,
    "stId" : "R-BTA-437181",
    "displayName" : "phospho-p-T410-PRKCZ [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48898,
    "identifier" : "A0JNH7",
    "standardIdentifier" : "uniprot:A0JNH7",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 10397982 ],
    "children" : [ ]
  }, {
    "dbId" : 10362130,
    "stId" : "R-BTA-372654",
    "displayName" : "DOCK1 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48898,
    "identifier" : "F1MIX6",
    "standardIdentifier" : "uniprot:F1MIX6",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "DOCK1" ],
    "parents" : [ 10398025, 10387938 ],
    "children" : [ ]
  }, {
    "dbId" : 202124,
    "stId" : "R-ALL-202124",
    "displayName" : "NO [cytosol]",
    "schemaClass" : "SimpleEntity",
    "speciesId" : 0,
    "diagramIds" : [ 97430 ],
    "identifier" : "16480",
    "standardIdentifier" : "chebi:16480",
    "referenceType" : "ReferenceMolecule",
    "parents" : [ ],
    "children" : [ ]
  }, {
    "dbId" : 10397969,
    "stId" : "R-BTA-5218793",
    "displayName" : "VEGFA:p-6Y-VEGFR2:NCK:p-S21,Y420-FYN:p-3Y-PAK2:CDC42:GTP [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 48898,
    "diagramIds" : [ 97467 ],
    "parents" : [ ],
    "children" : [ 10397960, 10397967 ]
  }, {
    "dbId" : 10397967,
    "stId" : "R-BTA-5218772",
    "displayName" : "p-3Y-PAK2 dimer:CDC42:GTP [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 48898,
    "parents" : [ 10397969 ],
    "children" : [ 10397965, 10347838 ]
  }, {
    "dbId" : 10397965,
    "stId" : "R-BTA-5218799",
    "displayName" : "p-3Y-PAK2 dimer [cytosol]",
    "schemaClass" : "Complex",
    "speciesId" : 48898,
    "parents" : [ 10397967 ],
    "children" : [ 10397963 ]
  }, {
    "dbId" : 10397963,
    "stId" : "R-BTA-5218705",
    "displayName" : "phospho-p-Y130,S141,T402-PAK2 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48898,
    "identifier" : "A0A3Q1M0G8",
    "standardIdentifier" : "uniprot:A0A3Q1M0G8",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 10397965 ],
    "children" : [ ]
  }, {
    "dbId" : 10397960,
    "stId" : "R-BTA-5218780",
    "displayName" : "VEGFA dimer:p-6Y-VEGFR2 dimer:NCK1,NCK2:p-S21,Y420-FYN [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 48898,
    "diagramIds" : [ 97453 ],
    "parents" : [ 10397969, 10398055, 10398066, 10398144 ],
    "children" : [ 10397955, 10397958 ]
  }, {
    "dbId" : 10397958,
    "stId" : "R-BTA-5218745",
    "displayName" : "phospho-p-S21,Y420-FYN [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48898,
    "identifier" : "A0JNB0",
    "standardIdentifier" : "uniprot:A0JNB0",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 10397960 ],
    "children" : [ ]
  }, {
    "dbId" : 10360583,
    "stId" : "R-BTA-2685645",
    "displayName" : "PAK2 dimer [cytosol]",
    "schemaClass" : "Complex",
    "speciesId" : 48898,
    "diagramIds" : [ 97456 ],
    "parents" : [ 10398064, 10398144 ],
    "children" : [ 10360581 ]
  }, {
    "dbId" : 10360581,
    "stId" : "R-BTA-211604",
    "displayName" : "PAK2 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48898,
    "identifier" : "A0A3Q1M0G8",
    "standardIdentifier" : "uniprot:A0A3Q1M0G8",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 10360583 ],
    "children" : [ ]
  }, {
    "dbId" : 10397955,
    "stId" : "R-BTA-5218798",
    "displayName" : "VEGFA dimer:p-6Y-VEGFR2 dimer:NCK1,NCK2 [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 48898,
    "diagramIds" : [ 97442 ],
    "parents" : [ 10397960, 10398000, 10397998 ],
    "children" : [ 10356560, 10395283 ]
  }, {
    "dbId" : 10394883,
    "stId" : "R-BTA-3858473",
    "displayName" : "RHOA:GTP:Mg2+ [cytosol]",
    "schemaClass" : "Complex",
    "speciesId" : 48898,
    "parents" : [ 10398120 ],
    "children" : [ 29438, 10364841, 29926 ]
  }, {
    "dbId" : 10351874,
    "stId" : "R-BTA-212509",
    "displayName" : "ROCK1 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48898,
    "identifier" : "F1MF50",
    "standardIdentifier" : "uniprot:F1MF50",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 10362263 ],
    "children" : [ ]
  }, {
    "dbId" : 10397953,
    "stId" : "R-BTA-189828",
    "displayName" : "MAP kinase p38 (Mg2+ cofactor) [cytosol]",
    "schemaClass" : "Complex",
    "speciesId" : 48898,
    "diagramIds" : [ 97471 ],
    "parents" : [ ],
    "children" : [ 29926, 10397951 ]
  }, {
    "dbId" : 10398014,
    "stId" : "R-BTA-5218781",
    "displayName" : "VEGFA:p-6Y-VEGFR2:p-SHB:p-7Y-PTK2:SRC-1:HSP90:PXN [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 48898,
    "diagramIds" : [ 97348 ],
    "parents" : [ ],
    "children" : [ 10398005, 10398012 ]
  }, {
    "dbId" : 10347836,
    "stId" : "R-BTA-449545",
    "displayName" : "CDC42 [plasma membrane]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48898,
    "identifier" : "Q2KJ93",
    "standardIdentifier" : "uniprot:Q2KJ93",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 10347838 ],
    "children" : [ ]
  }, {
    "dbId" : 10398012,
    "stId" : "R-BTA-5218757",
    "displayName" : "VEGFA:p-6Y-VEGFR2:p-SHB:p-6Y,S732-PTK2:SRC-1:HSP90AA1 [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 48898,
    "diagramIds" : [ 97344 ],
    "parents" : [ 10398014, 10398020, 10398041 ],
    "children" : [ 10348836, 10352229, 10398010 ]
  }, {
    "dbId" : 10347838,
    "stId" : "R-BTA-182921",
    "displayName" : "CDC42:GTP [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 48898,
    "diagramIds" : [ 97459 ],
    "parents" : [ 10397967, 10398053, 10398064 ],
    "children" : [ 29438, 10347836 ]
  }, {
    "dbId" : 10398010,
    "stId" : "R-BTA-5218760",
    "displayName" : "VEGFA:p-6Y-VEGFR2:p-SHB:p-6Y,S732-PTK2 [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 48898,
    "parents" : [ 10398012 ],
    "children" : [ 10398008, 10395290 ]
  }, {
    "dbId" : 10352952,
    "stId" : "R-BTA-201857",
    "displayName" : "G-actin [cytosol]",
    "schemaClass" : "Complex",
    "speciesId" : 48898,
    "parents" : [ 10364336 ],
    "children" : [ 10352950, 113592 ]
  }, {
    "dbId" : 10398008,
    "stId" : "R-BTA-5218694",
    "displayName" : "phospho-p-6Y,S732-PTK2 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48898,
    "identifier" : "A0A3Q1MAA1",
    "standardIdentifier" : "uniprot:A0A3Q1MAA1",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 10398010 ],
    "children" : [ ]
  }, {
    "dbId" : 10352948,
    "stId" : "R-BTA-201858",
    "displayName" : "ACTB [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48898,
    "identifier" : "P60712",
    "standardIdentifier" : "uniprot:P60712",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "ACTB" ],
    "parents" : [ 10352950 ],
    "children" : [ ]
  }, {
    "dbId" : 10351927,
    "stId" : "R-BTA-201621",
    "displayName" : "PTK2 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48898,
    "diagramIds" : [ 97306 ],
    "identifier" : "A0A3Q1MAA1",
    "standardIdentifier" : "uniprot:A0A3Q1MAA1",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 10396049 ],
    "children" : [ ]
  }, {
    "dbId" : 10445620,
    "stId" : "R-BTA-5673001",
    "displayName" : "RAF/MAP kinase cascade",
    "schemaClass" : "Pathway",
    "speciesId" : 48898,
    "diagramIds" : [ 97560 ]
  }, {
    "dbId" : 10352950,
    "stId" : "R-BTA-201859",
    "displayName" : "ACTB, ACTG1 [cytosol]",
    "schemaClass" : "DefinedSet",
    "speciesId" : 48898,
    "parents" : [ 10352952 ],
    "children" : [ 10352946, 10352948 ]
  }, {
    "dbId" : 10398005,
    "stId" : "R-BTA-210014",
    "displayName" : "PXN [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48898,
    "diagramIds" : [ 97347 ],
    "identifier" : "F1MFD1",
    "standardIdentifier" : "uniprot:F1MFD1",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 10398014 ],
    "children" : [ ]
  }, {
    "dbId" : 10356531,
    "stId" : "R-BTA-197954",
    "displayName" : "NCK1 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48898,
    "identifier" : "Q1LZB2",
    "standardIdentifier" : "uniprot:Q1LZB2",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "NCK1" ],
    "parents" : [ 10356560 ],
    "children" : [ ]
  }, {
    "dbId" : 10398000,
    "stId" : "R-BTA-5218795",
    "displayName" : "VEGFA dimer:p-6Y-VEGFR2 dimer:NCK1,NCK2:p-Y420-FYN [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 48898,
    "diagramIds" : [ 97448 ],
    "parents" : [ ],
    "children" : [ 10397955, 10361117 ]
  }, {
    "dbId" : 10352946,
    "stId" : "R-BTA-201861",
    "displayName" : "ACTG1 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48898,
    "identifier" : "P63258",
    "standardIdentifier" : "uniprot:P63258",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "ACTG1", "ACTG" ],
    "parents" : [ 10352950 ],
    "children" : [ ]
  }, {
    "dbId" : 10397998,
    "stId" : "R-BTA-5218786",
    "displayName" : "VEGFA dimer:p-6Y-VEGFR2 dimer:NCK1,NCK2:FYN [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 48898,
    "diagramIds" : [ 97445 ],
    "parents" : [ ],
    "children" : [ 10397955, 10341533 ]
  }, {
    "dbId" : 10362159,
    "stId" : "R-BTA-418992",
    "displayName" : "CDH5 [plasma membrane]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48898,
    "identifier" : "G3MZL1",
    "standardIdentifier" : "uniprot:G3MZL1",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "CDH5" ],
    "parents" : [ 10399266 ],
    "children" : [ ]
  }, {
    "dbId" : 10397993,
    "stId" : "R-BTA-5218758",
    "displayName" : "p-PKC [cytosol]",
    "schemaClass" : "DefinedSet",
    "speciesId" : 48898,
    "diagramIds" : [ 97500 ],
    "parents" : [ 10398060 ],
    "children" : [ 10397985, 10397989, 10397991 ]
  }, {
    "dbId" : 10397991,
    "stId" : "R-BTA-5218734",
    "displayName" : "phospho-p-T507,S645,S664-PRKCD [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48898,
    "identifier" : "F1MZX0",
    "standardIdentifier" : "uniprot:F1MZX0",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 10397993 ],
    "children" : [ ]
  }, {
    "dbId" : 113592,
    "stId" : "R-ALL-113592",
    "displayName" : "ATP [cytosol]",
    "schemaClass" : "SimpleEntity",
    "speciesId" : 0,
    "diagramIds" : [ 97475, 97350, 97417, 97485, 97294, 97301, 97492, 97371, 97498, 97309, 97315, 97506, 97378, 97511, 97447, 97385, 97451, 97519, 97392, 97331, 97397, 97462, 97338, 97466, 97343, 97470 ],
    "identifier" : "30616",
    "standardIdentifier" : "chebi:30616",
    "referenceType" : "ReferenceMolecule",
    "parents" : [ 10352952 ],
    "children" : [ ]
  }, {
    "dbId" : 10348836,
    "stId" : "R-BTA-191648",
    "displayName" : "SRC-2 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48898,
    "diagramIds" : [ 97488, 97304, 97368 ],
    "identifier" : "E1BIM8",
    "standardIdentifier" : "uniprot:E1BIM8",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "SRC" ],
    "parents" : [ 10395296, 10397939, 10398118, 10398012, 10396086 ],
    "children" : [ ]
  }, {
    "dbId" : 10397989,
    "stId" : "R-BTA-5218706",
    "displayName" : "phospho-p-T500,T642,S661-PRKCB [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48898,
    "identifier" : "P05126",
    "standardIdentifier" : "uniprot:P05126",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "PRKCB", "PRKCB1" ],
    "parents" : [ 10397993 ],
    "children" : [ ]
  }, {
    "dbId" : 10352417,
    "stId" : "R-BTA-202320",
    "displayName" : "PLCG1 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48898,
    "diagramIds" : [ 97482 ],
    "identifier" : "F1MYF9",
    "standardIdentifier" : "uniprot:F1MYF9",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 10396072 ],
    "children" : [ ]
  }, {
    "dbId" : 10397985,
    "stId" : "R-BTA-5218698",
    "displayName" : "phospho-p-T410,T563-PRKCZ [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48898,
    "identifier" : "A0JNH7",
    "standardIdentifier" : "uniprot:A0JNH7",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 10397993 ],
    "children" : [ ]
  }, {
    "dbId" : 10398047,
    "stId" : "R-BTA-5218776",
    "displayName" : "CRK:DOCK180:ELMO1,ELMO2:VEGFA:p-6Y-VEGFR2:p-SHB:p-7Y-PTK2:SRC-1:HSP90:p-12Y-BCAR1,VEGFA:p-6Y-VEGFR2:p-SHB:p-7Y-PTK2:SRC-1:HSP90:p-Y31,Y118-PXN [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 48898,
    "diagramIds" : [ 97359 ],
    "parents" : [ ],
    "children" : [ 10387938, 10398043 ]
  }, {
    "dbId" : 10398045,
    "stId" : "R-BTA-5218765",
    "displayName" : "VEGFA:p-6Y-VEGFR2:p-SHB:p-7Y-PTK2:SRC-1:HSP90:p-12Y-BCAR1/p-Y31,Y118-PAX:CRK [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 48898,
    "diagramIds" : [ 97356 ],
    "parents" : [ ],
    "children" : [ 10398043, 10345561 ]
  }, {
    "dbId" : 10398043,
    "stId" : "R-BTA-5218759",
    "displayName" : "VEGFA:p-6Y-VEGFR2:p-SHB:p-7Y-PTK2:SRC-1:HSP90:p-12Y-BCAR1,VEGFA:p-6Y-VEGFR2:p-SHB:p-7Y-PTK2:SRC-1:HSP90:p-Y31,Y118-PXN [plasma membrane]",
    "schemaClass" : "DefinedSet",
    "speciesId" : 48898,
    "diagramIds" : [ 97354 ],
    "parents" : [ 10398045, 10398047 ],
    "children" : [ 10398020, 10398041 ]
  }, {
    "dbId" : 10398041,
    "stId" : "R-BTA-5218762",
    "displayName" : "VEGFA:p-6Y-VEGFR2:p-SHB:p-7Y-PTK2:SRC-1:HSP90:p-12Y-BCAR1 [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 48898,
    "diagramIds" : [ 97530 ],
    "parents" : [ 10398043 ],
    "children" : [ 10398039, 10398012 ]
  }, {
    "dbId" : 1606609,
    "stId" : "R-ALL-1606609",
    "displayName" : "SPG [plasma membrane]",
    "schemaClass" : "SimpleEntity",
    "speciesId" : 0,
    "identifier" : "84410",
    "standardIdentifier" : "chebi:84410",
    "referenceType" : "ReferenceMolecule",
    "parents" : [ 10398157 ],
    "children" : [ ]
  }, {
    "dbId" : 10398039,
    "stId" : "R-BTA-5218739",
    "displayName" : "phospho-BCAR1 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48898,
    "identifier" : "A0A3Q1MQ07",
    "standardIdentifier" : "uniprot:A0A3Q1MQ07",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "BCAR1" ],
    "parents" : [ 10398041 ],
    "children" : [ ]
  }, {
    "dbId" : 10356560,
    "stId" : "R-BTA-381949",
    "displayName" : "NCK1,NCK2 [cytosol]",
    "schemaClass" : "DefinedSet",
    "speciesId" : 48898,
    "diagramIds" : [ 97441 ],
    "parents" : [ 10397955 ],
    "children" : [ 10356531, 10356558 ]
  }, {
    "dbId" : 10394960,
    "stId" : "R-BTA-3928564",
    "displayName" : "RHOA:GTP:ROCK1,ROCK2 [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 48898,
    "diagramIds" : [ 97327 ],
    "parents" : [ ],
    "children" : [ 10362263, 10341432 ]
  }, {
    "dbId" : 5218688,
    "stId" : "R-ALL-5218688",
    "displayName" : "S1P [plasma membrane]",
    "schemaClass" : "SimpleEntity",
    "speciesId" : 0,
    "diagramIds" : [ 97513 ],
    "identifier" : "60119",
    "standardIdentifier" : "chebi:60119",
    "referenceType" : "ReferenceMolecule",
    "parents" : [ ],
    "children" : [ ]
  }, {
    "dbId" : 10356558,
    "stId" : "R-BTA-204885",
    "displayName" : "NCK2 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48898,
    "identifier" : "A6H720",
    "standardIdentifier" : "uniprot:A6H720",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "NCK2" ],
    "parents" : [ 10356560 ],
    "children" : [ ]
  }, {
    "dbId" : 10398025,
    "stId" : "R-BTA-5218785",
    "displayName" : "DOCK180:ELMO1,ELMO2 [cytosol]",
    "schemaClass" : "Complex",
    "speciesId" : 48898,
    "diagramIds" : [ 97358 ],
    "parents" : [ ],
    "children" : [ 10387936, 10362130 ]
  }, {
    "dbId" : 10398020,
    "stId" : "R-BTA-5218756",
    "displayName" : "VEGFA:p-6Y-VEGFR2:p-SHB:p-7Y-PTK2:SRC-1:HSP90:p-Y31,Y118-PXN [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 48898,
    "diagramIds" : [ 97352 ],
    "parents" : [ 10398043 ],
    "children" : [ 10398018, 10398012 ]
  }, {
    "dbId" : 70106,
    "stId" : "R-ALL-70106",
    "displayName" : "H+ [cytosol]",
    "schemaClass" : "SimpleEntity",
    "speciesId" : 0,
    "diagramIds" : [ 97429, 97421, 97438 ],
    "identifier" : "15378",
    "standardIdentifier" : "chebi:15378",
    "referenceType" : "ReferenceMolecule",
    "parents" : [ ],
    "children" : [ ]
  }, {
    "dbId" : 10398018,
    "stId" : "R-BTA-5218693",
    "displayName" : "phospho-p-Y31,Y118-PXN [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48898,
    "identifier" : "F1MFD1",
    "standardIdentifier" : "uniprot:F1MFD1",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 10398020 ],
    "children" : [ ]
  }, {
    "dbId" : 10340732,
    "stId" : "R-BTA-57844",
    "displayName" : "PRKACA [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48898,
    "identifier" : "P00517",
    "standardIdentifier" : "uniprot:P00517",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 10398167 ],
    "children" : [ ]
  }, {
    "dbId" : 10398077,
    "stId" : "R-BTA-5218777",
    "displayName" : "VEGFA dimer:p-6Y-VEGFR2 dimer:PI3K [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 48898,
    "diagramIds" : [ 97536 ],
    "parents" : [ 10398089 ],
    "children" : [ 10395283, 10337713 ]
  }, {
    "dbId" : 10349944,
    "stId" : "R-BTA-549042",
    "displayName" : "NRP2 [plasma membrane]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48898,
    "diagramIds" : [ 97290 ],
    "identifier" : "E1BEL6",
    "standardIdentifier" : "uniprot:E1BEL6",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 10349946 ],
    "children" : [ ]
  }, {
    "dbId" : 10349946,
    "stId" : "R-BTA-195427",
    "displayName" : "NRP2:VEGFR1 dimer [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 48898,
    "diagramIds" : [ 97291 ],
    "parents" : [ ],
    "children" : [ 10349764, 10349944 ]
  }, {
    "dbId" : 10398073,
    "stId" : "R-BTA-5218779",
    "displayName" : "VEGFA:p-6Y-VEGFR2:Integrin alphaVbeta3 [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 48898,
    "diagramIds" : [ 97320 ],
    "parents" : [ 10398135, 10398140 ],
    "children" : [ 10395283, 10354217 ]
  }, {
    "dbId" : 5693375,
    "stId" : "R-ALL-5693375",
    "displayName" : "ADMA [cytosol]",
    "schemaClass" : "SimpleEntity",
    "speciesId" : 0,
    "diagramIds" : [ 97434 ],
    "identifier" : "58326",
    "standardIdentifier" : "chebi:58326",
    "referenceType" : "ReferenceMolecule",
    "parents" : [ ],
    "children" : [ ]
  }, {
    "dbId" : 10398066,
    "stId" : "R-BTA-5218782",
    "displayName" : "VEGFA:p-6Y-VEGFR2:NCK:p-S21,Y420-FYN:PAK2:CDC42:GTP [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 48898,
    "diagramIds" : [ 97460 ],
    "parents" : [ ],
    "children" : [ 10398064, 10397960 ]
  }, {
    "dbId" : 10349936,
    "stId" : "R-BTA-3008773",
    "displayName" : "NRP1 [plasma membrane]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48898,
    "diagramIds" : [ 97287 ],
    "identifier" : "E1BMX5",
    "standardIdentifier" : "uniprot:E1BMX5",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 10349938 ],
    "children" : [ ]
  }, {
    "dbId" : 10398064,
    "stId" : "R-BTA-5218770",
    "displayName" : "PAK2 dimer:CDC42:GTP [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 48898,
    "parents" : [ 10398066 ],
    "children" : [ 10360583, 10347838 ]
  }, {
    "dbId" : 10349938,
    "stId" : "R-BTA-195419",
    "displayName" : "NRP1:VEGFR2 dimer [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 48898,
    "diagramIds" : [ 97288 ],
    "parents" : [ ],
    "children" : [ 10349936, 10349740 ]
  }, {
    "dbId" : 10362225,
    "stId" : "R-BTA-418996",
    "displayName" : "CTNND1 [plasma membrane]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48898,
    "identifier" : "E1BQ11",
    "standardIdentifier" : "uniprot:E1BQ11",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "CTNND1" ],
    "parents" : [ 10399271, 10399266 ],
    "children" : [ ]
  }, {
    "dbId" : 10398060,
    "stId" : "R-BTA-5218773",
    "displayName" : "DAG:active PKC:Ca+2 [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 48898,
    "diagramIds" : [ 97504 ],
    "parents" : [ ],
    "children" : [ 10397993, 112275, 74016 ]
  }, {
    "dbId" : 10362221,
    "stId" : "R-BTA-418993",
    "displayName" : "Beta-catenin/gamma catenin [plasma membrane]",
    "schemaClass" : "DefinedSet",
    "speciesId" : 48898,
    "parents" : [ 10399271, 10399266 ],
    "children" : [ 10362215, 10362219 ]
  }, {
    "dbId" : 10362219,
    "stId" : "R-BTA-437260",
    "displayName" : "JUP [plasma membrane]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48898,
    "identifier" : "Q8SPJ1",
    "standardIdentifier" : "uniprot:Q8SPJ1",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "JUP" ],
    "parents" : [ 10362221 ],
    "children" : [ ]
  }, {
    "dbId" : 10349928,
    "stId" : "R-BTA-195361",
    "displayName" : "VEGF [extracellular region]",
    "schemaClass" : "DefinedSet",
    "speciesId" : 48898,
    "diagramIds" : [ 97272 ],
    "parents" : [ ],
    "children" : [ 10349730, 10349712, 10349748, 10349706, 10349754 ]
  }, {
    "dbId" : 10349930,
    "stId" : "R-BTA-195376",
    "displayName" : "VEGF dimer [extracellular region]",
    "schemaClass" : "DefinedSet",
    "speciesId" : 48898,
    "diagramIds" : [ 97273 ],
    "parents" : [ ],
    "children" : [ 10349714, 10349750, 10349732, 10349708, 10349756 ]
  }, {
    "dbId" : 10362215,
    "stId" : "R-BTA-191731",
    "displayName" : "beta-catenin [plasma membrane]",
    "schemaClass" : "CandidateSet",
    "speciesId" : 48898,
    "parents" : [ 10362221 ],
    "children" : [ 10362213 ]
  }, {
    "dbId" : 10398055,
    "stId" : "R-BTA-5218792",
    "displayName" : "VEGFA:p-6Y-VEGFR2:NCK:p-S21,Y420-FYN:p-2Y-PAK2:CDC42:GTP [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 48898,
    "diagramIds" : [ 97464 ],
    "parents" : [ ],
    "children" : [ 10398053, 10397960 ]
  }, {
    "dbId" : 10362213,
    "stId" : "R-BTA-9038440",
    "displayName" : "CTNNB1 [plasma membrane]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48898,
    "identifier" : "Q0VCX4",
    "standardIdentifier" : "uniprot:Q0VCX4",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "CTNNB1" ],
    "parents" : [ 10362215 ],
    "children" : [ ]
  }, {
    "dbId" : 10398053,
    "stId" : "R-BTA-5218800",
    "displayName" : "p-2Y-PAK2 dimer:CDC42:GTP [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 48898,
    "parents" : [ 10398055 ],
    "children" : [ 10398051, 10347838 ]
  }, {
    "dbId" : 10362211,
    "stId" : "R-BTA-191735",
    "displayName" : "CTNNA1 [plasma membrane]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48898,
    "identifier" : "A0A3Q1M9M0",
    "standardIdentifier" : "uniprot:A0A3Q1M9M0",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "CTNNA1" ],
    "parents" : [ 10399271, 10399266 ],
    "children" : [ ]
  }, {
    "dbId" : 10398051,
    "stId" : "R-BTA-5218794",
    "displayName" : "p-2Y-PAK2 dimer [cytosol]",
    "schemaClass" : "Complex",
    "speciesId" : 48898,
    "parents" : [ 10398053 ],
    "children" : [ 10361353 ]
  } ],
  "edges" : [ {
    "dbId" : 10398110,
    "stId" : "R-BTA-5218823",
    "displayName" : "PKC phosphorylates sphingosine kinase 1",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "preceding" : [ 10398062 ],
    "following" : [ 10398160 ],
    "inputs" : [ 113592, 10361004 ],
    "outputs" : [ 29370, 10398107 ],
    "catalysts" : [ 10398060 ],
    "efs" : [ ],
    "diagramIds" : [ 97505 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10399262,
    "stId" : "R-BTA-5357429",
    "displayName" : "AXL autophosphorylates on Y779 and Y821",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "preceding" : [ 10399264 ],
    "following" : [ 10399276 ],
    "inputs" : [ 113592, 10399259 ],
    "outputs" : [ 10398085, 29370 ],
    "catalysts" : [ 10399259 ],
    "efs" : [ ],
    "diagramIds" : [ 97377 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10349726,
    "stId" : "R-BTA-194308",
    "displayName" : "VEGF-C,D bind to VEGFR3 leading to receptor dimerization",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "preceding" : [ 10349932 ],
    "inputs" : [ 10349716, 10349720 ],
    "outputs" : [ 10349724 ],
    "efs" : [ ],
    "diagramIds" : [ 97282 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10398104,
    "stId" : "R-BTA-5218822",
    "displayName" : "CRK binds BCAR1 and or PXN",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "preceding" : [ 10398023 ],
    "following" : [ 10398049 ],
    "inputs" : [ 10398043, 10345561 ],
    "outputs" : [ 10398045 ],
    "efs" : [ ],
    "diagramIds" : [ 97353 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10396057,
    "stId" : "R-BTA-4420099",
    "displayName" : "p-6Y-VEGFR2 binds SHB ",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "preceding" : [ 10396070 ],
    "following" : [ 10396078 ],
    "inputs" : [ 10395283, 10396053 ],
    "outputs" : [ 10396055 ],
    "efs" : [ ],
    "diagramIds" : [ 97297 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10398102,
    "stId" : "R-BTA-5218821",
    "displayName" : "PDK1 phosphorylates PKC",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "following" : [ 10397996 ],
    "inputs" : [ 10398100, 113592 ],
    "outputs" : [ 29370, 10397982 ],
    "catalysts" : [ 10340055 ],
    "efs" : [ ],
    "diagramIds" : [ 97491 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10397972,
    "stId" : "R-BTA-5218804",
    "displayName" : "p38 MAPK activation by VEGFR",
    "schemaClass" : "BlackBoxEvent",
    "speciesId" : 0,
    "preceding" : [ 10398058 ],
    "following" : [ 10348154 ],
    "inputs" : [ 10397953, 113592 ],
    "outputs" : [ 29370, 10348151 ],
    "catalysts" : [ 10397969 ],
    "efs" : [ ],
    "diagramIds" : [ 97469 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10396051,
    "stId" : "R-BTA-4420083",
    "displayName" : "PTK2 binds p-S-SHB and is recruited to p-6Y-VEGFR2",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "preceding" : [ 10396078 ],
    "following" : [ 10397945 ],
    "inputs" : [ 10351927, 10395290 ],
    "outputs" : [ 10396049 ],
    "efs" : [ ],
    "diagramIds" : [ 97305 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10398096,
    "stId" : "R-BTA-5218820",
    "displayName" : "Src kinases phosphorylate VAV",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "preceding" : [ 10397949 ],
    "inputs" : [ 113592, 10364856 ],
    "outputs" : [ 29370, 10398094 ],
    "catalysts" : [ 10397939 ],
    "efs" : [ ],
    "diagramIds" : [ 97390 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10398092,
    "stId" : "R-BTA-5218819",
    "displayName" : "VEGFA dimer:p-6Y-VEGFR2 dimer:PI3K phosphorylates PIP2 to PIP3",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "preceding" : [ 10399276 ],
    "following" : [ 10388406 ],
    "inputs" : [ 113592, 179856 ],
    "outputs" : [ 179838, 29370 ],
    "catalysts" : [ 10398089 ],
    "efs" : [ ],
    "diagramIds" : [ 97384 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10352266,
    "stId" : "R-BTA-202144",
    "displayName" : "Caveolin-1 dissociates from eNOS:CaM:HSP90 complex",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "preceding" : [ 10352251 ],
    "inputs" : [ 10352248 ],
    "outputs" : [ 10352263, 10352223 ],
    "catalysts" : [ 10352248 ],
    "efs" : [ ],
    "diagramIds" : [ 97413 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10396094,
    "stId" : "R-BTA-4420202",
    "displayName" : "PLCG1 disassociates from VEGFR2 and translocate to PM",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "preceding" : [ 10396076 ],
    "inputs" : [ 10396074 ],
    "outputs" : [ 10352562, 10395283 ],
    "efs" : [ ],
    "diagramIds" : [ 97489 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10398142,
    "stId" : "R-BTA-5218830",
    "displayName" : "SRC-1 phosphorylates PTK2-beta",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "preceding" : [ 10398148, 10397949 ],
    "following" : [ 10398165 ],
    "inputs" : [ 10398135, 113592 ],
    "outputs" : [ 29370, 10398140 ],
    "catalysts" : [ 10397939 ],
    "efs" : [ ],
    "diagramIds" : [ 97337 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10396092,
    "stId" : "R-BTA-4420153",
    "displayName" : "p-6Y-VEGFR2 binds PLCG1",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "preceding" : [ 10396070 ],
    "following" : [ 10396076 ],
    "inputs" : [ 10395283, 10352417 ],
    "outputs" : [ 10396072 ],
    "efs" : [ ],
    "diagramIds" : [ 97481 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10396090,
    "stId" : "R-BTA-4420143",
    "displayName" : "p-6Y-VEGFR2 binds SH2D2A",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "preceding" : [ 10396070 ],
    "following" : [ 10396088 ],
    "inputs" : [ 10395283, 10396082 ],
    "outputs" : [ 10396084 ],
    "efs" : [ ],
    "diagramIds" : [ 97364 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10396088,
    "stId" : "R-BTA-4420140",
    "displayName" : "SRC1-1 binds SH2D2A and is recruited to VEGFR2",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "preceding" : [ 10396090 ],
    "following" : [ 10396099 ],
    "inputs" : [ 10396084, 10348836 ],
    "outputs" : [ 10396086 ],
    "efs" : [ ],
    "diagramIds" : [ 97367 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10388406,
    "stId" : "R-BTA-2316429",
    "displayName" : "PIP3 recruits PDPK1 to the membrane",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "preceding" : [ 10398092 ],
    "inputs" : [ 179838, 10352268 ],
    "outputs" : [ 10340057 ],
    "efs" : [ ],
    "diagramIds" : [ 97402 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10398003,
    "stId" : "R-BTA-5218806",
    "displayName" : "FYN autophosphorylates",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "preceding" : [ 10398112 ],
    "following" : [ 10398170 ],
    "inputs" : [ 113592, 10397998 ],
    "outputs" : [ 10398000, 29370 ],
    "catalysts" : [ 10397998 ],
    "efs" : [ ],
    "diagramIds" : [ 97446 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10349744,
    "stId" : "R-BTA-194310",
    "displayName" : "VEGF-A,C,D bind to VEGFR2 leading to receptor dimerization",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "preceding" : [ 10349932 ],
    "following" : [ 10396070 ],
    "inputs" : [ 10349734, 10349738 ],
    "outputs" : [ 10349742 ],
    "efs" : [ ],
    "diagramIds" : [ 97278 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10396078,
    "stId" : "R-BTA-4420128",
    "displayName" : "SRC-1 phosphorylates SHB",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "preceding" : [ 10396057 ],
    "following" : [ 10396051 ],
    "inputs" : [ 10396055, 113592 ],
    "outputs" : [ 29370, 10395290 ],
    "catalysts" : [ 10348836 ],
    "efs" : [ ],
    "diagramIds" : [ 97300 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10396076,
    "stId" : "R-BTA-4420121",
    "displayName" : "SFKs phosphorylate PLCG1",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "preceding" : [ 10396092 ],
    "following" : [ 10396094 ],
    "inputs" : [ 113592, 10396072 ],
    "outputs" : [ 29370, 10396074 ],
    "catalysts" : [ 10348836 ],
    "efs" : [ ],
    "diagramIds" : [ 97484 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10397996,
    "stId" : "R-BTA-5218805",
    "displayName" : "PKC autophosphorylates",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "preceding" : [ 10398102 ],
    "following" : [ 10398062 ],
    "inputs" : [ 113592, 10397982 ],
    "outputs" : [ 29370, 10397993 ],
    "catalysts" : [ 10397982 ],
    "efs" : [ ],
    "diagramIds" : [ 97497 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10399276,
    "stId" : "R-BTA-5357479",
    "displayName" : "p-AXL binds PI3K",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "preceding" : [ 10399262 ],
    "following" : [ 10398092 ],
    "inputs" : [ 10337713, 10398085 ],
    "outputs" : [ 10398087 ],
    "efs" : [ ],
    "diagramIds" : [ 97381 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10399274,
    "stId" : "R-BTA-5357477",
    "displayName" : "PAK1-3 phosphorylates VE-cadherin",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "inputs" : [ 10399266, 113592 ],
    "outputs" : [ 29370, 10399271 ],
    "catalysts" : [ 10361359 ],
    "efs" : [ ],
    "diagramIds" : [ 97396 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10398123,
    "stId" : "R-BTA-5218826",
    "displayName" : "Active ROCK1,ROCK2 phosphorylates p-5Y-PTK2 on S732",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "preceding" : [ 10398328, 10397947 ],
    "following" : [ 10398165 ],
    "inputs" : [ 10395298, 113592 ],
    "outputs" : [ 29370, 10398118 ],
    "catalysts" : [ 10398120 ],
    "efs" : [ ],
    "diagramIds" : [ 97330 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10396070,
    "stId" : "R-BTA-4420117",
    "displayName" : "VEGFR2 autophosphorylates",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "preceding" : [ 10349744, 10434147 ],
    "following" : [ 10396065, 10398071, 10398075, 10396057, 10396090, 10396092 ],
    "inputs" : [ 10396067, 113592, 10349738 ],
    "outputs" : [ 10395283, 29370 ],
    "catalysts" : [ 10396067 ],
    "efs" : [ ],
    "diagramIds" : [ 97292 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10395300,
    "stId" : "R-BTA-3928647",
    "displayName" : "RHOA:GTP:Mg2+ binds ROCK1,ROCK2",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "preceding" : [ 10397947 ],
    "following" : [ 10398328 ],
    "inputs" : [ 10362263, 10341432 ],
    "outputs" : [ 10394960 ],
    "efs" : [ ],
    "activators" : [ 10395298 ],
    "diagramIds" : [ 97324 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10398112,
    "stId" : "R-BTA-5218824",
    "displayName" : "p-6Y-VEGFR2 binds FYN",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "preceding" : [ 10398071 ],
    "following" : [ 10398003 ],
    "inputs" : [ 10397955, 10341533 ],
    "outputs" : [ 10397998 ],
    "efs" : [ ],
    "diagramIds" : [ 97443 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10399264,
    "stId" : "R-BTA-5357432",
    "displayName" : "AXL binds SRC-1",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "preceding" : [ 10396099 ],
    "following" : [ 10399262 ],
    "inputs" : [ 10396096, 10399257 ],
    "outputs" : [ 10399259 ],
    "efs" : [ ],
    "diagramIds" : [ 97374 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10396065,
    "stId" : "R-BTA-4420107",
    "displayName" : "p-6Y-VEGFR2 binds SHC-transforming protein 2",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "preceding" : [ 10396070 ],
    "inputs" : [ 10395283, 10396061 ],
    "outputs" : [ 10396063 ],
    "efs" : [ ],
    "diagramIds" : [ 97360 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10352217,
    "stId" : "R-BTA-202110",
    "displayName" : "eNOS:Caveolin-1 complex binds to CaM",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "following" : [ 10352251 ],
    "inputs" : [ 10352208, 10340783 ],
    "outputs" : [ 10352214 ],
    "catalysts" : [ 10352208 ],
    "efs" : [ ],
    "diagramIds" : [ 97406 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10398170,
    "stId" : "R-BTA-5218854",
    "displayName" : "p-Y420-FYN is phosphorylated on S21",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "preceding" : [ 10398003 ],
    "following" : [ 10398162 ],
    "inputs" : [ 10398000, 113592 ],
    "outputs" : [ 29370, 10397960 ],
    "catalysts" : [ 10398167 ],
    "efs" : [ ],
    "diagramIds" : [ 97450 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10378583,
    "stId" : "R-BTA-1497784",
    "displayName" : "The cofactor BH4 is required for electron transfer in the eNOS catalytic cycle",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "preceding" : [ 10352241 ],
    "following" : [ 10352246 ],
    "inputs" : [ 29870, 10352238 ],
    "outputs" : [ 10352243 ],
    "catalysts" : [ 10352238 ],
    "efs" : [ ],
    "diagramIds" : [ 97422 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10398165,
    "stId" : "R-BTA-5218851",
    "displayName" : "p-Y402-PTK2B phosphorylates p-5Y,S732-PTK2 on Y407",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "preceding" : [ 10398123, 10398142 ],
    "following" : [ 10398150 ],
    "inputs" : [ 113592, 10398118 ],
    "outputs" : [ 29370, 10398012 ],
    "catalysts" : [ 10398140 ],
    "efs" : [ ],
    "diagramIds" : [ 97342 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10398162,
    "stId" : "R-BTA-5218847",
    "displayName" : "PAK2 binds NCK",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "preceding" : [ 10398170 ],
    "following" : [ 10398146 ],
    "inputs" : [ 10360583, 10397960 ],
    "outputs" : [ 10398144 ],
    "efs" : [ ],
    "diagramIds" : [ 97455 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10398160,
    "stId" : "R-BTA-5218845",
    "displayName" : "p-SPHK1 phosphorylates sphingosine to sphingosine 1-phosphate",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "preceding" : [ 10398110 ],
    "inputs" : [ 113592, 10398157 ],
    "outputs" : [ 5218688, 10346033, 10348033, 29370 ],
    "catalysts" : [ 10398107 ],
    "efs" : [ ],
    "diagramIds" : [ 97510 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10398155,
    "stId" : "R-BTA-5218841",
    "displayName" : "NADPH oxidase 2 generates superoxide from oxygen",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "inputs" : [ 29364, 352327 ],
    "outputs" : [ 70106, 29366, 3299686 ],
    "catalysts" : [ 10398152 ],
    "efs" : [ ],
    "diagramIds" : [ 97435 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10349768,
    "stId" : "R-BTA-194311",
    "displayName" : "VEGFA,B,PLGF bind to VEGFR1 leading to receptor dimerization",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "preceding" : [ 10349932 ],
    "inputs" : [ 10349762, 10349758 ],
    "outputs" : [ 10349766 ],
    "efs" : [ ],
    "diagramIds" : [ 97274 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10398150,
    "stId" : "R-BTA-5218838",
    "displayName" : "PXN binds p-6Y,S732-PTK2",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "preceding" : [ 10398165 ],
    "following" : [ 10398023 ],
    "inputs" : [ 10398005, 10398012 ],
    "outputs" : [ 10398014 ],
    "efs" : [ ],
    "diagramIds" : [ 97346 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10398023,
    "stId" : "R-BTA-5218809",
    "displayName" : "PTK2 and SRC-1 phosphorylate PXN on Y31 and Y118",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "preceding" : [ 10398150 ],
    "following" : [ 10398104 ],
    "inputs" : [ 113592, 10398014 ],
    "outputs" : [ 10398020, 29370 ],
    "catalysts" : [ 10398014 ],
    "efs" : [ ],
    "diagramIds" : [ 97349 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10398148,
    "stId" : "R-BTA-5218836",
    "displayName" : "PTK2beta binds alphaVbeta3",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "preceding" : [ 10398075 ],
    "following" : [ 10398142 ],
    "inputs" : [ 10360976, 10398073 ],
    "outputs" : [ 10398135 ],
    "efs" : [ ],
    "diagramIds" : [ 97334 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10398146,
    "stId" : "R-BTA-5218832",
    "displayName" : "CDC42:GTP binds PAK2",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "preceding" : [ 10398162 ],
    "following" : [ 10398069 ],
    "inputs" : [ 10398144, 10347838 ],
    "outputs" : [ 10398066 ],
    "efs" : [ ],
    "diagramIds" : [ 97458 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10396099,
    "stId" : "R-BTA-4420206",
    "displayName" : "Phosphorylation of SRC-1",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "preceding" : [ 10396088 ],
    "following" : [ 10399264 ],
    "inputs" : [ 113592, 10396086 ],
    "outputs" : [ 10396096, 29370 ],
    "catalysts" : [ 10396086 ],
    "efs" : [ ],
    "diagramIds" : [ 97370 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10433986,
    "stId" : "R-BTA-9679477",
    "displayName" : "VEGFA-165 dimer binds VEGFA inhibitors",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "inputs" : [ 10395271, 9679456 ],
    "outputs" : [ 10433984 ],
    "efs" : [ ],
    "diagramIds" : [ 97524 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10349948,
    "stId" : "R-BTA-195418",
    "displayName" : "NRP-2 associates with VEGFR1 forming complexes on  cell surface",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "inputs" : [ 10349762, 10349944 ],
    "outputs" : [ 10349946 ],
    "efs" : [ ],
    "diagramIds" : [ 97289 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10397949,
    "stId" : "R-BTA-5218645",
    "displayName" : "SRC-1 binds p-Y397-PTK2",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "preceding" : [ 10397945 ],
    "following" : [ 10398096, 10397942, 10398142 ],
    "inputs" : [ 10397937, 10348836 ],
    "outputs" : [ 10397939 ],
    "efs" : [ ],
    "diagramIds" : [ 97312 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10397947,
    "stId" : "R-BTA-5218643",
    "displayName" : "HSP90AA1 binds p-6Y-VEGFR2",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "preceding" : [ 10397942 ],
    "following" : [ 10398123, 10395300 ],
    "inputs" : [ 10395296, 10352229 ],
    "outputs" : [ 10395298 ],
    "efs" : [ ],
    "diagramIds" : [ 97321 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10398075,
    "stId" : "R-BTA-5218818",
    "displayName" : "Integrin alphaVbeta3 binds p-6Y-VEGFR2",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "preceding" : [ 10396070 ],
    "following" : [ 10398148 ],
    "inputs" : [ 10395283, 10354217 ],
    "outputs" : [ 10398073 ],
    "efs" : [ ],
    "diagramIds" : [ 97318 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10352251,
    "stId" : "R-BTA-202129",
    "displayName" : "HSP90 binds eNOS:Caveolin-1:CaM complex",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "preceding" : [ 10352217 ],
    "following" : [ 10352266 ],
    "inputs" : [ 10352214, 10352229 ],
    "outputs" : [ 10352248, 10340783 ],
    "catalysts" : [ 10352229 ],
    "efs" : [ ],
    "diagramIds" : [ 97410 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10398328,
    "stId" : "R-BTA-5228992",
    "displayName" : "ROCK1,ROCK2 are activated",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "preceding" : [ 10395300 ],
    "following" : [ 10398123 ],
    "inputs" : [ 10394960 ],
    "outputs" : [ 10398120 ],
    "efs" : [ ],
    "diagramIds" : [ 97328 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10348154,
    "stId" : "R-BTA-187688",
    "displayName" : "p38 MAPK phosphorylates MAPKAPK2, MAPKAPK3",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "preceding" : [ 10397972 ],
    "following" : [ 10398195 ],
    "inputs" : [ 113592, 10348132 ],
    "outputs" : [ 29370, 10348143 ],
    "catalysts" : [ 10348151 ],
    "efs" : [ ],
    "diagramIds" : [ 97517 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10397945,
    "stId" : "R-BTA-5218642",
    "displayName" : "PTK2 autophosphorylates",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "preceding" : [ 10396051 ],
    "following" : [ 10397949 ],
    "inputs" : [ 10396049, 113592 ],
    "outputs" : [ 10397937, 29370 ],
    "catalysts" : [ 10396049 ],
    "efs" : [ ],
    "diagramIds" : [ 97308 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10397942,
    "stId" : "R-BTA-5218640",
    "displayName" : "SRC-1 phosphorylates p-Y397-PTK2",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "preceding" : [ 10397949 ],
    "following" : [ 10397947 ],
    "inputs" : [ 10397939, 113592 ],
    "outputs" : [ 10395296, 29370 ],
    "catalysts" : [ 10397939 ],
    "efs" : [ ],
    "diagramIds" : [ 97314 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10349940,
    "stId" : "R-BTA-195408",
    "displayName" : "NRP-1 forms a ternary complex with VEGF165 and VEGFR1",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "inputs" : [ 10349936, 10349738 ],
    "outputs" : [ 10349938 ],
    "efs" : [ ],
    "diagramIds" : [ 97286 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10398071,
    "stId" : "R-BTA-5218815",
    "displayName" : "p-6Y-VEGFR2 binds NCK",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "preceding" : [ 10396070 ],
    "following" : [ 10398112 ],
    "inputs" : [ 10356560, 10395283 ],
    "outputs" : [ 10397955 ],
    "efs" : [ ],
    "diagramIds" : [ 97440 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10352246,
    "stId" : "R-BTA-202127",
    "displayName" : "eNOS synthesizes NO",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "preceding" : [ 10378583 ],
    "inputs" : [ 29468, 70106, 29368, 29364 ],
    "outputs" : [ 202124, 29356, 29366, 29968 ],
    "catalysts" : [ 10352243 ],
    "efs" : [ ],
    "inhibitors" : [ 5693375 ],
    "diagramIds" : [ 97425 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10398069,
    "stId" : "R-BTA-5218814",
    "displayName" : "PAK2 autophorylates",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "preceding" : [ 10398146 ],
    "following" : [ 10398058 ],
    "inputs" : [ 10398066, 113592 ],
    "outputs" : [ 29370, 10398055 ],
    "catalysts" : [ 10398066 ],
    "efs" : [ ],
    "diagramIds" : [ 97461 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10352241,
    "stId" : "R-BTA-202111",
    "displayName" : "AKT1 phosphorylates eNOS",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "following" : [ 10378583 ],
    "inputs" : [ 10352227, 113592 ],
    "outputs" : [ 70106, 29370, 10352238 ],
    "catalysts" : [ 10352227 ],
    "efs" : [ ],
    "diagramIds" : [ 97416 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10398195,
    "stId" : "R-BTA-5218916",
    "displayName" : "p-MAPK2/3 phosphorylates HSP27",
    "schemaClass" : "BlackBoxEvent",
    "speciesId" : 0,
    "preceding" : [ 10348154 ],
    "inputs" : [ 113592, 10398187 ],
    "outputs" : [ 10398192, 10364336, 29370 ],
    "catalysts" : [ 10348143 ],
    "efs" : [ ],
    "diagramIds" : [ 97474 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10398062,
    "stId" : "R-BTA-5218813",
    "displayName" : "DAG and Ca+2 bind to PKC and tether it to membrane",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "preceding" : [ 10397996 ],
    "following" : [ 10398110 ],
    "inputs" : [ 10397993, 112275, 74016 ],
    "outputs" : [ 10398060 ],
    "efs" : [ ],
    "diagramIds" : [ 97501 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10349932,
    "stId" : "R-BTA-195378",
    "displayName" : "Homodimerization of VEGF proteins",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "following" : [ 10349726, 10349768, 10349744 ],
    "inputs" : [ 10349928 ],
    "outputs" : [ 10349930 ],
    "efs" : [ ],
    "diagramIds" : [ 97271 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10398058,
    "stId" : "R-BTA-5218812",
    "displayName" : "FYN phosphorylates PAK2",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "preceding" : [ 10398069 ],
    "following" : [ 10397972 ],
    "inputs" : [ 10398055, 113592 ],
    "outputs" : [ 10397969, 29370 ],
    "catalysts" : [ 10398055 ],
    "efs" : [ ],
    "diagramIds" : [ 97465 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10434147,
    "stId" : "R-BTA-9691215",
    "displayName" : "VEGFA-165 dimer binds VEGFR2 dimer",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "following" : [ 10396070 ],
    "inputs" : [ 10395271, 10349738 ],
    "outputs" : [ 10396067 ],
    "efs" : [ ],
    "inhibitors" : [ 10433984 ],
    "diagramIds" : [ 97521 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10398049,
    "stId" : "R-BTA-5218811",
    "displayName" : "DOCK180:ELMO binds CRK",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "preceding" : [ 10398104 ],
    "inputs" : [ 10398025, 10398045 ],
    "outputs" : [ 10398047 ],
    "efs" : [ ],
    "diagramIds" : [ 97357 ],
    "entityFunctionalStatus" : [ ]
  } ],
  "subpathways" : [ {
    "dbId" : 10444036,
    "stId" : "R-BTA-194313",
    "displayName" : "VEGF ligand-receptor interactions",
    "events" : [ 10349932, 10349726, 10349768, 10349744 ]
  }, {
    "dbId" : 10443900,
    "stId" : "R-BTA-4420097",
    "displayName" : "VEGFA-VEGFR2 Pathway",
    "events" : [ 10396094, 10398062, 10398110, 10396092, 10396076, 10397996, 10398102, 10398160, 10396065, 10398049, 10398112, 10399264, 10434147, 10395300, 10399274, 10352217, 10352251, 10352266, 10388406, 10378583, 10352246, 10352241, 10396070, 10398123, 10398058, 10399276, 10396078, 10398195, 10398003, 10398069, 10398071, 10397942, 10348154, 10397945, 10396088, 10398328, 10397947, 10398075, 10396090, 10397949, 10398142, 10396099, 10433986, 10398146, 10398148, 10398023, 10398150, 10398155, 10398092, 10398096, 10396051, 10398162, 10398165, 10397972, 10396057, 10398104, 10398170, 10399262 ]
  }, {
    "dbId" : 10444134,
    "stId" : "R-BTA-5218920",
    "displayName" : "VEGFR2 mediated vascular permeability",
    "events" : [ 10399274, 10352217, 10352251, 10352266, 10388406, 10378583, 10352246, 10352241 ]
  }, {
    "dbId" : 10444034,
    "stId" : "R-BTA-195399",
    "displayName" : "VEGF binds to VEGFR leading to receptor dimerization",
    "events" : [ 10349726, 10349768, 10349744 ]
  }, {
    "dbId" : 10445408,
    "stId" : "R-BTA-5218921",
    "displayName" : "VEGFR2 mediated cell proliferation",
    "events" : [ 10396094, 10398062, 10398110, 10396092, 10396076, 10397996, 10398102, 10398160 ]
  }, {
    "dbId" : 10444046,
    "stId" : "R-BTA-194306",
    "displayName" : "Neuropilin interactions with VEGF and VEGFR",
    "events" : [ 10349948, 10349940 ]
  } ]
}