{
  "dbId" : 10444938,
  "stId" : "R-BTA-1234174",
  "speciesName" : "Bos taurus",
  "nodes" : [ {
    "dbId" : 10375324,
    "stId" : "R-BTA-1234148",
    "displayName" : "hydroxyAsn-HIF1A,HIF2A [cytosol]",
    "schemaClass" : "DefinedSet",
    "speciesId" : 48898,
    "diagramIds" : [ 63487 ],
    "parents" : [ ],
    "children" : [ 10375319, 10375322 ]
  }, {
    "dbId" : 9918612,
    "stId" : "R-BTA-9918612",
    "displayName" : "bPSMD13 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48898,
    "identifier" : "Q5E964",
    "standardIdentifier" : "uniprot:Q5E964",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "PSMD13" ],
    "parents" : [ 10333313 ],
    "children" : [ ]
  }, {
    "dbId" : 10333337,
    "stId" : "R-BTA-9907918",
    "displayName" : "20S core particle [cytosol]",
    "schemaClass" : "Complex",
    "speciesId" : 48898,
    "parents" : [ 10333339 ],
    "children" : [ 9918669, 10333335 ]
  }, {
    "dbId" : 10375322,
    "stId" : "R-BTA-1234110",
    "displayName" : "HIF1A [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48898,
    "identifier" : "A0JND0",
    "standardIdentifier" : "uniprot:A0JND0",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "HIF1A" ],
    "parents" : [ 10375324 ],
    "children" : [ ]
  }, {
    "dbId" : 10338971,
    "stId" : "R-BTA-1234098",
    "displayName" : "ARNT [nucleoplasm]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48898,
    "diagramIds" : [ 63516 ],
    "identifier" : "A0A3Q1LKX3",
    "standardIdentifier" : "uniprot:A0A3Q1LKX3",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "ARNT" ],
    "parents" : [ 10375354 ],
    "children" : [ ]
  }, {
    "dbId" : 113671,
    "stId" : "R-ALL-113671",
    "displayName" : "2OG [nucleoplasm]",
    "schemaClass" : "SimpleEntity",
    "speciesId" : 0,
    "diagramIds" : [ 63526 ],
    "identifier" : "16810",
    "standardIdentifier" : "chebi:16810",
    "referenceType" : "ReferenceMolecule",
    "parents" : [ ],
    "children" : [ ]
  }, {
    "dbId" : 10333339,
    "stId" : "R-BTA-68819",
    "displayName" : "26S proteasome [cytosol]",
    "schemaClass" : "Complex",
    "speciesId" : 48898,
    "diagramIds" : [ 63511 ],
    "parents" : [ ],
    "children" : [ 10333329, 10333337 ]
  }, {
    "dbId" : 10332827,
    "stId" : "R-BTA-68524",
    "displayName" : "Ub [nucleoplasm]",
    "schemaClass" : "DefinedSet",
    "speciesId" : 48898,
    "parents" : [ 10375389, 10375391 ],
    "children" : [ 10332797, 10332793, 10332809, 10332801 ]
  }, {
    "dbId" : 10333333,
    "stId" : "R-BTA-68759",
    "displayName" : "PSMB7 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48898,
    "identifier" : "F1MBI1",
    "standardIdentifier" : "uniprot:F1MBI1",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "PSMB7" ],
    "parents" : [ 10333335 ],
    "children" : [ ]
  }, {
    "dbId" : 10375319,
    "stId" : "R-BTA-1234112",
    "displayName" : "EPAS1 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48898,
    "identifier" : "A5PJT1",
    "standardIdentifier" : "uniprot:A5PJT1",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "EPAS1" ],
    "parents" : [ 10375324 ],
    "children" : [ ]
  }, {
    "dbId" : 10333335,
    "stId" : "R-BTA-9907905",
    "displayName" : "20S CP inner ring [cytosol]",
    "schemaClass" : "Complex",
    "speciesId" : 48898,
    "parents" : [ 10333337 ],
    "children" : [ 9918680, 9918681, 10333331, 9918685, 10333333, 9918672, 9918678 ]
  }, {
    "dbId" : 10375316,
    "stId" : "R-BTA-1234109",
    "displayName" : "HIF1A,HIF2A [cytosol]",
    "schemaClass" : "DefinedSet",
    "speciesId" : 48898,
    "diagramIds" : [ 63482 ],
    "parents" : [ ],
    "children" : [ 10375293, 10375295 ]
  }, {
    "dbId" : 10333329,
    "stId" : "R-BTA-9908177",
    "displayName" : "19S regulatory particle [cytosol]",
    "schemaClass" : "Complex",
    "speciesId" : 48898,
    "parents" : [ 10333339 ],
    "children" : [ 10333327, 10333309 ]
  }, {
    "dbId" : 10333331,
    "stId" : "R-BTA-68738",
    "displayName" : "PSMB1 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48898,
    "identifier" : "G5E589",
    "standardIdentifier" : "uniprot:G5E589",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "PSMB1" ],
    "parents" : [ 10333335 ],
    "children" : [ ]
  }, {
    "dbId" : 9918616,
    "stId" : "R-BTA-9918616",
    "displayName" : "bPSMD11 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48898,
    "identifier" : "Q2KI42",
    "standardIdentifier" : "uniprot:Q2KI42",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "PSMD11" ],
    "parents" : [ 10333315 ],
    "children" : [ ]
  }, {
    "dbId" : 9918599,
    "stId" : "R-BTA-9918599",
    "displayName" : "bPSMC4 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48898,
    "identifier" : "Q3T030",
    "standardIdentifier" : "uniprot:Q3T030",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "PSMC4" ],
    "parents" : [ 9918587 ],
    "children" : [ ]
  }, {
    "dbId" : 10333325,
    "stId" : "R-BTA-68808",
    "displayName" : "PSMD8 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48898,
    "identifier" : "F1MYH8",
    "standardIdentifier" : "uniprot:F1MYH8",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "PSMD8" ],
    "parents" : [ 10333327 ],
    "children" : [ ]
  }, {
    "dbId" : 10375311,
    "stId" : "R-BTA-1234125",
    "displayName" : "hydroxyPro-HIF-alpha:VHL:EloB,C:CUL2:RBX1:LIMD1,AJUBA,WTIP:PHD2,3 [cytosol]",
    "schemaClass" : "Complex",
    "speciesId" : 48898,
    "diagramIds" : [ 63502 ],
    "parents" : [ ],
    "children" : [ 10375249, 10375283 ]
  }, {
    "dbId" : 9918598,
    "stId" : "R-BTA-9918598",
    "displayName" : "bPSMD3 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48898,
    "identifier" : "Q2KJ46",
    "standardIdentifier" : "uniprot:Q2KJ46",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "PSMD3" ],
    "parents" : [ 10333321 ],
    "children" : [ ]
  }, {
    "dbId" : 10333327,
    "stId" : "R-BTA-9908021",
    "displayName" : "19S RP lid [cytosol]",
    "schemaClass" : "Complex",
    "speciesId" : 48898,
    "parents" : [ 10333329 ],
    "children" : [ 10333323, 10333325 ]
  }, {
    "dbId" : 113685,
    "stId" : "R-ALL-113685",
    "displayName" : "O2 [nucleoplasm]",
    "schemaClass" : "SimpleEntity",
    "speciesId" : 0,
    "diagramIds" : [ 63525 ],
    "identifier" : "15379",
    "standardIdentifier" : "chebi:15379",
    "referenceType" : "ReferenceMolecule",
    "parents" : [ ],
    "children" : [ ]
  }, {
    "dbId" : 10333321,
    "stId" : "R-BTA-9908004",
    "displayName" : "19S RP lid particle 3 [cytosol]",
    "schemaClass" : "Complex",
    "speciesId" : 48898,
    "parents" : [ 10333323 ],
    "children" : [ 10333319, 10333317, 9918598 ]
  }, {
    "dbId" : 10332809,
    "stId" : "R-BTA-939871",
    "displayName" : "UBC [nucleoplasm]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48898,
    "identifier" : "P0CH28",
    "standardIdentifier" : "uniprot:P0CH28",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "UBC" ],
    "parents" : [ 10332827 ],
    "children" : [ ]
  }, {
    "dbId" : 10375307,
    "stId" : "R-BTA-1234153",
    "displayName" : "HIF-alpha [nucleoplasm]",
    "schemaClass" : "DefinedSet",
    "speciesId" : 48898,
    "diagramIds" : [ 63514 ],
    "parents" : [ 10375354 ],
    "children" : [ 10375301, 10375303, 10375305 ]
  }, {
    "dbId" : 9918593,
    "stId" : "R-BTA-9918593",
    "displayName" : "bPSMC5 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48898,
    "identifier" : "P62194",
    "standardIdentifier" : "uniprot:P62194",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "PSMC5", "SUG1" ],
    "parents" : [ 9918587 ],
    "children" : [ ]
  }, {
    "dbId" : 10333323,
    "stId" : "R-BTA-9908012",
    "displayName" : "19S RP lid particle 2 [cytosol]",
    "schemaClass" : "Complex",
    "speciesId" : 48898,
    "parents" : [ 10333327 ],
    "children" : [ 10333315, 10333321 ]
  }, {
    "dbId" : 10375305,
    "stId" : "R-BTA-9717059",
    "displayName" : "HIF3A [nucleoplasm]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48898,
    "diagramIds" : [ 63533 ],
    "identifier" : "F6RL11",
    "standardIdentifier" : "uniprot:F6RL11",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "HIF3A" ],
    "parents" : [ 10375307 ],
    "children" : [ ]
  }, {
    "dbId" : 10333317,
    "stId" : "R-BTA-68804",
    "displayName" : "PSMD6 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48898,
    "identifier" : "F1MXE4",
    "standardIdentifier" : "uniprot:F1MXE4",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "PSMD6" ],
    "parents" : [ 10333321 ],
    "children" : [ ]
  }, {
    "dbId" : 9918607,
    "stId" : "R-BTA-9918607",
    "displayName" : "bPSMD12 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48898,
    "identifier" : "Q2KJ25",
    "standardIdentifier" : "uniprot:Q2KJ25",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "PSMD12" ],
    "parents" : [ 10333313 ],
    "children" : [ ]
  }, {
    "dbId" : 10375303,
    "stId" : "R-BTA-1234135",
    "displayName" : "HIF1A [nucleoplasm]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48898,
    "diagramIds" : [ 63527 ],
    "identifier" : "A0JND0",
    "standardIdentifier" : "uniprot:A0JND0",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "HIF1A" ],
    "parents" : [ 10375307 ],
    "children" : [ ]
  }, {
    "dbId" : 10333319,
    "stId" : "R-BTA-8866674",
    "displayName" : "Ghost homologue of SEM1 [cytosol]",
    "schemaClass" : "GenomeEncodedEntity",
    "speciesId" : 48898,
    "parents" : [ 10333321 ],
    "children" : [ ]
  }, {
    "dbId" : 10375301,
    "stId" : "R-BTA-452560",
    "displayName" : "EPAS1 [nucleoplasm]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48898,
    "diagramIds" : [ 63549 ],
    "identifier" : "A5PJT1",
    "standardIdentifier" : "uniprot:A5PJT1",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "EPAS1" ],
    "parents" : [ 10375307 ],
    "children" : [ ]
  }, {
    "dbId" : 10333313,
    "stId" : "R-BTA-9907994",
    "displayName" : "PSMD7:PSMD12:PSMD13:PSMD14 [cytosol]",
    "schemaClass" : "Complex",
    "speciesId" : 48898,
    "parents" : [ 10333315 ],
    "children" : [ 9918585, 9918607, 9918612, 10333311 ]
  }, {
    "dbId" : 10332801,
    "stId" : "R-BTA-939847",
    "displayName" : "RPS27A [nucleoplasm]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48898,
    "identifier" : "P62992",
    "standardIdentifier" : "uniprot:P62992",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "RPS27A" ],
    "parents" : [ 10332827 ],
    "children" : [ ]
  }, {
    "dbId" : 10375299,
    "stId" : "R-BTA-1234147",
    "displayName" : "HIF-alpha [cytosol]",
    "schemaClass" : "DefinedSet",
    "speciesId" : 48898,
    "diagramIds" : [ 63513 ],
    "parents" : [ ],
    "children" : [ 10375297, 10375293, 10375295 ]
  }, {
    "dbId" : 10333315,
    "stId" : "R-BTA-9907993",
    "displayName" : "19S RP Lid Module 1 [cytosol]",
    "schemaClass" : "Complex",
    "speciesId" : 48898,
    "parents" : [ 10333323 ],
    "children" : [ 9918616, 10333313 ]
  }, {
    "dbId" : 10375297,
    "stId" : "R-BTA-9717043",
    "displayName" : "HIF3A [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48898,
    "diagramIds" : [ 63498 ],
    "identifier" : "F6RL11",
    "standardIdentifier" : "uniprot:F6RL11",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "HIF3A" ],
    "parents" : [ 10375299 ],
    "children" : [ ]
  }, {
    "dbId" : 10375356,
    "stId" : "R-BTA-1234099",
    "displayName" : "HIF:CBP:p300 [nucleoplasm]",
    "schemaClass" : "Complex",
    "speciesId" : 48898,
    "diagramIds" : [ 63522 ],
    "parents" : [ ],
    "children" : [ 10354897, 29428, 10375354, 10370413 ]
  }, {
    "dbId" : 10375354,
    "stId" : "R-BTA-1234130",
    "displayName" : "HIF [nucleoplasm]",
    "schemaClass" : "Complex",
    "speciesId" : 48898,
    "diagramIds" : [ 63517 ],
    "parents" : [ 10375356 ],
    "children" : [ 10338971, 10375307 ]
  }, {
    "dbId" : 10346168,
    "stId" : "R-BTA-205341",
    "displayName" : "UBE2D3 [nucleoplasm]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48898,
    "identifier" : "A0A3Q1M5N0",
    "standardIdentifier" : "uniprot:A0A3Q1M5N0",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "UBE2D3" ],
    "parents" : [ 10375387 ],
    "children" : [ ]
  }, {
    "dbId" : 10375349,
    "stId" : "R-BTA-1234124",
    "displayName" : "PHD1,3 [nucleoplasm]",
    "schemaClass" : "DefinedSet",
    "speciesId" : 48898,
    "diagramIds" : [ 63531 ],
    "parents" : [ ],
    "children" : [ 10375347, 10375341 ]
  }, {
    "dbId" : 10375347,
    "stId" : "R-BTA-9640400",
    "displayName" : "EGLN2:AscH-:Fe2+ [nucleoplasm]",
    "schemaClass" : "Complex",
    "speciesId" : 48898,
    "parents" : [ 10375349 ],
    "children" : [ 10375345, 5251226, 111793 ]
  }, {
    "dbId" : 10375345,
    "stId" : "R-BTA-1234117",
    "displayName" : "EGLN2 [nucleoplasm]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48898,
    "identifier" : "A0A3Q1LUX2",
    "standardIdentifier" : "uniprot:A0A3Q1LUX2",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "EGLN2" ],
    "parents" : [ 10375347 ],
    "children" : [ ]
  }, {
    "dbId" : 10375341,
    "stId" : "R-BTA-9640401",
    "displayName" : "EGLN3:AscH-:Fe2+ [nucleoplasm]",
    "schemaClass" : "Complex",
    "speciesId" : 48898,
    "parents" : [ 10375349 ],
    "children" : [ 5251226, 10375339, 111793 ]
  }, {
    "dbId" : 10375339,
    "stId" : "R-BTA-1234104",
    "displayName" : "EGLN3 [nucleoplasm]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48898,
    "identifier" : "A7MBA0",
    "standardIdentifier" : "uniprot:A7MBA0",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "EGLN3" ],
    "parents" : [ 10375341 ],
    "children" : [ ]
  }, {
    "dbId" : 10375337,
    "stId" : "R-BTA-1234140",
    "displayName" : "HIF3A [nucleoplasm]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48898,
    "diagramIds" : [ 63534 ],
    "identifier" : "F6RL11",
    "standardIdentifier" : "uniprot:F6RL11",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "HIF3A" ],
    "parents" : [ 10375369 ],
    "children" : [ ]
  }, {
    "dbId" : 10375332,
    "stId" : "R-BTA-1235007",
    "displayName" : "FIH1:AscH-:Fe2+ dimer [cytosol]",
    "schemaClass" : "Complex",
    "speciesId" : 48898,
    "diagramIds" : [ 63488 ],
    "parents" : [ ],
    "children" : [ 10375330 ]
  }, {
    "dbId" : 10375330,
    "stId" : "R-BTA-9640410",
    "displayName" : "FIH1:AscH-:Fe2+ [cytosol]",
    "schemaClass" : "Complex",
    "speciesId" : 48898,
    "parents" : [ 10375332 ],
    "children" : [ 10375328, 71067, 198816 ]
  }, {
    "dbId" : 10375328,
    "stId" : "R-BTA-1234154",
    "displayName" : "HIF1AN [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48898,
    "identifier" : "F1MG82",
    "standardIdentifier" : "uniprot:F1MG82",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "HIF1AN" ],
    "parents" : [ 10375330 ],
    "children" : [ ]
  }, {
    "dbId" : 9918679,
    "stId" : "R-BTA-9918679",
    "displayName" : "bPSMA4 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48898,
    "identifier" : "Q3ZCK9",
    "standardIdentifier" : "uniprot:Q3ZCK9",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "PSMA4" ],
    "parents" : [ 9918669 ],
    "children" : [ ]
  }, {
    "dbId" : 9918678,
    "stId" : "R-BTA-9918678",
    "displayName" : "bPSMB6 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48898,
    "identifier" : "Q3MHN0",
    "standardIdentifier" : "uniprot:Q3MHN0",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "PSMB6" ],
    "parents" : [ 10333335 ],
    "children" : [ ]
  }, {
    "dbId" : 10375391,
    "stId" : "R-BTA-1234100",
    "displayName" : "ub-hydroxyPro-HIF-alpha [nucleoplasm]",
    "schemaClass" : "Complex",
    "speciesId" : 48898,
    "parents" : [ 10375393 ],
    "children" : [ 10375369, 10332827 ]
  }, {
    "dbId" : 9918677,
    "stId" : "R-BTA-9918677",
    "displayName" : "bPSMA2 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48898,
    "identifier" : "Q3T0Y5",
    "standardIdentifier" : "uniprot:Q3T0Y5",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "PSMA2" ],
    "parents" : [ 9918669 ],
    "children" : [ ]
  }, {
    "dbId" : 9918676,
    "stId" : "R-BTA-9918676",
    "displayName" : "bPSMA7 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48898,
    "identifier" : "Q3ZBG0",
    "standardIdentifier" : "uniprot:Q3ZBG0",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "PSMA7" ],
    "parents" : [ 9918669 ],
    "children" : [ ]
  }, {
    "dbId" : 10375389,
    "stId" : "R-BTA-1234123",
    "displayName" : "UBE2D1,2,3:Ubiquitin [nucleoplasm]",
    "schemaClass" : "Complex",
    "speciesId" : 48898,
    "diagramIds" : [ 63540 ],
    "parents" : [ ],
    "children" : [ 10332827, 10375387 ]
  }, {
    "dbId" : 9918675,
    "stId" : "R-BTA-9918675",
    "displayName" : "bPSMA3 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48898,
    "identifier" : "Q58DU5",
    "standardIdentifier" : "uniprot:Q58DU5",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "PSMA3" ],
    "parents" : [ 9918669 ],
    "children" : [ ]
  }, {
    "dbId" : 10375387,
    "stId" : "R-BTA-1234118",
    "displayName" : "UBE2D1,2,3 [nucleoplasm]",
    "schemaClass" : "DefinedSet",
    "speciesId" : 48898,
    "diagramIds" : [ 63541 ],
    "parents" : [ 10375389 ],
    "children" : [ 10332897, 10375385, 10346168 ]
  }, {
    "dbId" : 9918672,
    "stId" : "R-BTA-9918672",
    "displayName" : "bPSMB4 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48898,
    "identifier" : "Q3T108",
    "standardIdentifier" : "uniprot:Q3T108",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "PSMB4" ],
    "parents" : [ 10333335 ],
    "children" : [ ]
  }, {
    "dbId" : 10375385,
    "stId" : "R-BTA-8852067",
    "displayName" : "UBE2D2 [nucleoplasm]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48898,
    "identifier" : "Q1RMX2",
    "standardIdentifier" : "uniprot:Q1RMX2",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "UBE2D2" ],
    "parents" : [ 10375387 ],
    "children" : [ ]
  }, {
    "dbId" : 9918685,
    "stId" : "R-BTA-9918685",
    "displayName" : "bPSMB5 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48898,
    "identifier" : "Q32KL2",
    "standardIdentifier" : "uniprot:Q32KL2",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "PSMB5" ],
    "parents" : [ 10333335 ],
    "children" : [ ]
  }, {
    "dbId" : 9918684,
    "stId" : "R-BTA-9918684",
    "displayName" : "bPSMA1 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48898,
    "identifier" : "Q3T0X5",
    "standardIdentifier" : "uniprot:Q3T0X5",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "PSMA1" ],
    "parents" : [ 9918669 ],
    "children" : [ ]
  }, {
    "dbId" : 9918683,
    "stId" : "R-BTA-9918683",
    "displayName" : "bPSMA5 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48898,
    "identifier" : "Q5E987",
    "standardIdentifier" : "uniprot:Q5E987",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "PSMA5" ],
    "parents" : [ 9918669 ],
    "children" : [ ]
  }, {
    "dbId" : 10375379,
    "stId" : "R-BTA-1234101",
    "displayName" : "hydroxyPro-HIF-alpha:VHL:EloB,C:CUL2:RBX1 [nucleoplasm]",
    "schemaClass" : "Complex",
    "speciesId" : 48898,
    "diagramIds" : [ 63538 ],
    "parents" : [ ],
    "children" : [ 10375377, 10375369 ]
  }, {
    "dbId" : 9918681,
    "stId" : "R-BTA-9918681",
    "displayName" : "bPSMB3 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48898,
    "identifier" : "P33672",
    "standardIdentifier" : "uniprot:P33672",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "PSMB3" ],
    "parents" : [ 10333335 ],
    "children" : [ ]
  }, {
    "dbId" : 10354897,
    "stId" : "R-BTA-193545",
    "displayName" : "CREBBP [nucleoplasm]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48898,
    "diagramIds" : [ 63520 ],
    "identifier" : "F1MD32",
    "standardIdentifier" : "uniprot:F1MD32",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "CREBBP" ],
    "parents" : [ 10375356 ],
    "children" : [ ]
  }, {
    "dbId" : 9918680,
    "stId" : "R-BTA-9918680",
    "displayName" : "bPSMB2 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48898,
    "identifier" : "Q5E9K0",
    "standardIdentifier" : "uniprot:Q5E9K0",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "PSMB2" ],
    "parents" : [ 10333335 ],
    "children" : [ ]
  }, {
    "dbId" : 10375377,
    "stId" : "R-BTA-1234141",
    "displayName" : "VHL:EloB,C:CUL2:RBX1 [nucleoplasm]",
    "schemaClass" : "Complex",
    "speciesId" : 48898,
    "diagramIds" : [ 63536 ],
    "parents" : [ 10375393, 10375379 ],
    "children" : [ 10333252, 10375373, 10375375 ]
  }, {
    "dbId" : 10375375,
    "stId" : "R-BTA-1234126",
    "displayName" : "CUL2 [nucleoplasm]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48898,
    "identifier" : "Q08DE9",
    "standardIdentifier" : "uniprot:Q08DE9",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "CUL2" ],
    "parents" : [ 10375377 ],
    "children" : [ ]
  }, {
    "dbId" : 10375373,
    "stId" : "R-BTA-1234128",
    "displayName" : "VBC Complex [nucleoplasm]",
    "schemaClass" : "Complex",
    "speciesId" : 48898,
    "parents" : [ 10375377 ],
    "children" : [ 10341121, 10375371, 10341117 ]
  }, {
    "dbId" : 10375371,
    "stId" : "R-BTA-1234127",
    "displayName" : "VHL [nucleoplasm]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48898,
    "identifier" : "E1BL53",
    "standardIdentifier" : "uniprot:E1BL53",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 10375373 ],
    "children" : [ ]
  }, {
    "dbId" : 10375369,
    "stId" : "R-BTA-1234132",
    "displayName" : "hydroxyPro-HIF-alpha [nucleoplasm]",
    "schemaClass" : "DefinedSet",
    "speciesId" : 48898,
    "diagramIds" : [ 63537 ],
    "parents" : [ 10375391, 10375379 ],
    "children" : [ 10375365, 10375367, 10375337 ]
  }, {
    "dbId" : 10375367,
    "stId" : "R-BTA-1234105",
    "displayName" : "HIF1A [nucleoplasm]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48898,
    "diagramIds" : [ 63530 ],
    "identifier" : "A0JND0",
    "standardIdentifier" : "uniprot:A0JND0",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "HIF1A" ],
    "parents" : [ 10375369 ],
    "children" : [ ]
  }, {
    "dbId" : 9918670,
    "stId" : "R-BTA-9918670",
    "displayName" : "bPSMA6 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48898,
    "identifier" : "Q2YDE4",
    "standardIdentifier" : "uniprot:Q2YDE4",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "PSMA6" ],
    "parents" : [ 9918669 ],
    "children" : [ ]
  }, {
    "dbId" : 9918669,
    "stId" : "R-BTA-9918669",
    "displayName" : "b20S CP outer ring [cytosol]",
    "schemaClass" : "Complex",
    "speciesId" : 48898,
    "parents" : [ 10333337 ],
    "children" : [ 9918683, 9918684, 9918670, 9918675, 9918676, 9918677, 9918679 ]
  }, {
    "dbId" : 10375365,
    "stId" : "R-BTA-1234151",
    "displayName" : "EPAS1 [nucleoplasm]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48898,
    "diagramIds" : [ 63550 ],
    "identifier" : "A5PJT1",
    "standardIdentifier" : "uniprot:A5PJT1",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "EPAS1" ],
    "parents" : [ 10375369 ],
    "children" : [ ]
  }, {
    "dbId" : 10375360,
    "stId" : "R-BTA-6804489",
    "displayName" : "CITED2 [nucleoplasm]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48898,
    "diagramIds" : [ 63523 ],
    "identifier" : "Q0VCT9",
    "standardIdentifier" : "uniprot:Q0VCT9",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "CITED2" ],
    "parents" : [ ],
    "children" : [ ]
  }, {
    "dbId" : 10341117,
    "stId" : "R-BTA-112422",
    "displayName" : "ELOC [nucleoplasm]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48898,
    "identifier" : "Q2KII4",
    "standardIdentifier" : "uniprot:Q2KII4",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "ELOC" ],
    "parents" : [ 10375373 ],
    "children" : [ ]
  }, {
    "dbId" : 113528,
    "stId" : "R-ALL-113528",
    "displayName" : "CO2 [cytosol]",
    "schemaClass" : "SimpleEntity",
    "speciesId" : 0,
    "diagramIds" : [ 63494, 63486 ],
    "identifier" : "16526",
    "standardIdentifier" : "chebi:16526",
    "referenceType" : "ReferenceMolecule",
    "parents" : [ ],
    "children" : [ ]
  }, {
    "dbId" : 10332897,
    "stId" : "R-BTA-174197",
    "displayName" : "UBE2D1 [nucleoplasm]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48898,
    "identifier" : "Q2TA10",
    "standardIdentifier" : "uniprot:Q2TA10",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "UBE2D1" ],
    "parents" : [ 10375387 ],
    "children" : [ ]
  }, {
    "dbId" : 10333408,
    "stId" : "R-BTA-174236",
    "displayName" : "UBE2D1 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48898,
    "identifier" : "Q2TA10",
    "standardIdentifier" : "uniprot:Q2TA10",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "UBE2D1" ],
    "parents" : [ 10345488 ],
    "children" : [ ]
  }, {
    "dbId" : 10375393,
    "stId" : "R-BTA-1234103",
    "displayName" : "ub-HIF-alpha:VHL:EloB,C:CUL2:RBX1 [nucleoplasm]",
    "schemaClass" : "Complex",
    "speciesId" : 48898,
    "diagramIds" : [ 63542 ],
    "parents" : [ ],
    "children" : [ 10375377, 10375391 ]
  }, {
    "dbId" : 10353936,
    "stId" : "R-BTA-180582",
    "displayName" : "RBX1 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48898,
    "identifier" : "A0A3Q1LNF8",
    "standardIdentifier" : "uniprot:A0A3Q1LNF8",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 10373237 ],
    "children" : [ ]
  }, {
    "dbId" : 10345488,
    "stId" : "R-BTA-1234120",
    "displayName" : "UBE2D1,2,3 [cytosol]",
    "schemaClass" : "DefinedSet",
    "speciesId" : 48898,
    "diagramIds" : [ 63505 ],
    "parents" : [ 10345490 ],
    "children" : [ 10333408, 10345482, 10345486 ]
  }, {
    "dbId" : 10345490,
    "stId" : "R-BTA-1234116",
    "displayName" : "UBE2D1,2,3:Ubiquitin [cytosol]",
    "schemaClass" : "Complex",
    "speciesId" : 48898,
    "diagramIds" : [ 63504 ],
    "parents" : [ ],
    "children" : [ 10345488, 10333291 ]
  }, {
    "dbId" : 10345486,
    "stId" : "R-BTA-934630",
    "displayName" : "UBE2D3 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48898,
    "identifier" : "A0A3Q1M5N0",
    "standardIdentifier" : "uniprot:A0A3Q1M5N0",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "UBE2D3" ],
    "parents" : [ 10345488 ],
    "children" : [ ]
  }, {
    "dbId" : 10345482,
    "stId" : "R-BTA-934628",
    "displayName" : "UBE2D2 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48898,
    "identifier" : "Q1RMX2",
    "standardIdentifier" : "uniprot:Q1RMX2",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "UBE2D2" ],
    "parents" : [ 10345488 ],
    "children" : [ ]
  }, {
    "dbId" : 71067,
    "stId" : "R-ALL-71067",
    "displayName" : "Fe2+ [cytosol]",
    "schemaClass" : "SimpleEntity",
    "speciesId" : 0,
    "identifier" : "29033",
    "standardIdentifier" : "chebi:29033",
    "chebiIdentifier" : "chebi:29033",
    "referenceType" : "ReferenceMolecule",
    "parents" : [ 10375330, 10375279, 10375273 ],
    "children" : [ ]
  }, {
    "dbId" : 10341121,
    "stId" : "R-BTA-112423",
    "displayName" : "TCEB2 [nucleoplasm]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48898,
    "identifier" : "Q3SZ32",
    "standardIdentifier" : "uniprot:Q3SZ32",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "TCEB2" ],
    "parents" : [ 10375373 ],
    "children" : [ ]
  }, {
    "dbId" : 198816,
    "stId" : "R-ALL-198816",
    "displayName" : "AscH- [cytosol]",
    "schemaClass" : "SimpleEntity",
    "speciesId" : 0,
    "identifier" : "38290",
    "standardIdentifier" : "chebi:38290",
    "referenceType" : "ReferenceMolecule",
    "parents" : [ 10375279, 10375273, 10375330 ],
    "children" : [ ]
  }, {
    "dbId" : 111793,
    "stId" : "R-ALL-111793",
    "displayName" : "Fe2+ [nucleoplasm]",
    "schemaClass" : "SimpleEntity",
    "speciesId" : 0,
    "identifier" : "29033",
    "standardIdentifier" : "chebi:29033",
    "chebiIdentifier" : "chebi:29033",
    "referenceType" : "ReferenceMolecule",
    "parents" : [ 10375341, 10375347 ],
    "children" : [ ]
  }, {
    "dbId" : 29368,
    "stId" : "R-ALL-29368",
    "displayName" : "O2 [cytosol]",
    "schemaClass" : "SimpleEntity",
    "speciesId" : 0,
    "diagramIds" : [ 63491, 63483 ],
    "identifier" : "15379",
    "standardIdentifier" : "chebi:15379",
    "referenceType" : "ReferenceMolecule",
    "parents" : [ ],
    "children" : [ ]
  }, {
    "dbId" : 159939,
    "stId" : "R-ALL-159939",
    "displayName" : "SUCCA [nucleoplasm]",
    "schemaClass" : "SimpleEntity",
    "speciesId" : 0,
    "diagramIds" : [ 63528 ],
    "identifier" : "30031",
    "standardIdentifier" : "chebi:30031",
    "referenceType" : "ReferenceMolecule",
    "parents" : [ ],
    "children" : [ ]
  }, {
    "dbId" : 10375261,
    "stId" : "R-BTA-2564698",
    "displayName" : "AJUBA [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48898,
    "identifier" : "E1BKA3",
    "standardIdentifier" : "uniprot:E1BKA3",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "AJUBA" ],
    "parents" : [ 10375267 ],
    "children" : [ ]
  }, {
    "dbId" : 159942,
    "stId" : "R-ALL-159942",
    "displayName" : "CO2 [nucleoplasm]",
    "schemaClass" : "SimpleEntity",
    "speciesId" : 0,
    "diagramIds" : [ 63529 ],
    "identifier" : "16526",
    "standardIdentifier" : "chebi:16526",
    "referenceType" : "ReferenceMolecule",
    "parents" : [ ],
    "children" : [ ]
  }, {
    "dbId" : 10333273,
    "stId" : "R-BTA-939188",
    "displayName" : "UBC [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48898,
    "identifier" : "P0CH28",
    "standardIdentifier" : "uniprot:P0CH28",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "UBC" ],
    "parents" : [ 10333291 ],
    "children" : [ ]
  }, {
    "dbId" : 10375257,
    "stId" : "R-BTA-8932473",
    "displayName" : "LIMD1 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48898,
    "identifier" : "G5E5X0",
    "standardIdentifier" : "uniprot:G5E5X0",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "LIMD1" ],
    "parents" : [ 10375267 ],
    "children" : [ ]
  }, {
    "dbId" : 5251226,
    "stId" : "R-ALL-5251226",
    "displayName" : "AscH- [nucleoplasm]",
    "schemaClass" : "SimpleEntity",
    "speciesId" : 0,
    "identifier" : "38290",
    "standardIdentifier" : "chebi:38290",
    "referenceType" : "ReferenceMolecule",
    "parents" : [ 10375347, 10375341 ],
    "children" : [ ]
  }, {
    "dbId" : 10375253,
    "stId" : "R-BTA-1234138",
    "displayName" : "ub-hydroxyPro-HIF-alpha:VHL:EloB:EloC:CUL2:RBX1 [cytosol]",
    "schemaClass" : "Complex",
    "speciesId" : 48898,
    "diagramIds" : [ 63544 ],
    "parents" : [ 10375287 ],
    "children" : [ 10375251, 10373237 ]
  }, {
    "dbId" : 10333265,
    "stId" : "R-BTA-939203",
    "displayName" : "UBA52 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48898,
    "identifier" : "P63048",
    "standardIdentifier" : "uniprot:P63048",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "UBA52" ],
    "parents" : [ 10333291 ],
    "children" : [ ]
  }, {
    "dbId" : 10375251,
    "stId" : "R-BTA-1234113",
    "displayName" : "ub-hydroxyPro-HIF-alpha [cytosol]",
    "schemaClass" : "Complex",
    "speciesId" : 48898,
    "parents" : [ 10375253, 10375285 ],
    "children" : [ 10375249, 10333291 ]
  }, {
    "dbId" : 10333267,
    "stId" : "R-BTA-939214",
    "displayName" : "RPS27A [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48898,
    "identifier" : "P62992",
    "standardIdentifier" : "uniprot:P62992",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "RPS27A" ],
    "parents" : [ 10333291 ],
    "children" : [ ]
  }, {
    "dbId" : 10375249,
    "stId" : "R-BTA-1234106",
    "displayName" : "hydroxyPro-HIF-alpha [cytosol]",
    "schemaClass" : "DefinedSet",
    "speciesId" : 48898,
    "diagramIds" : [ 63501 ],
    "parents" : [ 10375251, 10375311 ],
    "children" : [ 10375236, 10375242, 10375247 ]
  }, {
    "dbId" : 10375247,
    "stId" : "R-BTA-1234129",
    "displayName" : "HIF3A [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48898,
    "diagramIds" : [ 63499 ],
    "identifier" : "F6RL11",
    "standardIdentifier" : "uniprot:F6RL11",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "HIF3A" ],
    "parents" : [ 10375249 ],
    "children" : [ ]
  }, {
    "dbId" : 10333263,
    "stId" : "R-BTA-939205",
    "displayName" : "UBB [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48898,
    "identifier" : "P0CG53",
    "standardIdentifier" : "uniprot:P0CG53",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "UBB" ],
    "parents" : [ 10333291 ],
    "children" : [ ]
  }, {
    "dbId" : 10375242,
    "stId" : "R-BTA-1234131",
    "displayName" : "HIF1A [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48898,
    "diagramIds" : [ 63493 ],
    "identifier" : "A0JND0",
    "standardIdentifier" : "uniprot:A0JND0",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "HIF1A" ],
    "parents" : [ 10375249 ],
    "children" : [ ]
  }, {
    "dbId" : 10333252,
    "stId" : "R-BTA-1234142",
    "displayName" : "RBX1 [nucleoplasm]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48898,
    "identifier" : "A0A3Q1LNF8",
    "standardIdentifier" : "uniprot:A0A3Q1LNF8",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 10375377 ],
    "children" : [ ]
  }, {
    "dbId" : 10375236,
    "stId" : "R-BTA-1234149",
    "displayName" : "EPAS1 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48898,
    "diagramIds" : [ 63548 ],
    "identifier" : "A5PJT1",
    "standardIdentifier" : "uniprot:A5PJT1",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "EPAS1" ],
    "parents" : [ 10375249 ],
    "children" : [ ]
  }, {
    "dbId" : 29406,
    "stId" : "R-ALL-29406",
    "displayName" : "2OG [cytosol]",
    "schemaClass" : "SimpleEntity",
    "speciesId" : 0,
    "diagramIds" : [ 63492, 63484 ],
    "identifier" : "16810",
    "standardIdentifier" : "chebi:16810",
    "referenceType" : "ReferenceMolecule",
    "parents" : [ ],
    "children" : [ ]
  }, {
    "dbId" : 10333309,
    "stId" : "R-BTA-9908170",
    "displayName" : "19S RP base [cytosol]",
    "schemaClass" : "Complex",
    "speciesId" : 48898,
    "parents" : [ 10333329 ],
    "children" : [ 10333299, 9918587, 10333297, 9918589, 10333307 ]
  }, {
    "dbId" : 10332797,
    "stId" : "R-BTA-939844",
    "displayName" : "UBA52 [nucleoplasm]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48898,
    "identifier" : "P63048",
    "standardIdentifier" : "uniprot:P63048",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "UBA52" ],
    "parents" : [ 10332827 ],
    "children" : [ ]
  }, {
    "dbId" : 10375295,
    "stId" : "R-BTA-1234102",
    "displayName" : "HIF1A [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48898,
    "diagramIds" : [ 63490 ],
    "identifier" : "A0JND0",
    "standardIdentifier" : "uniprot:A0JND0",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "HIF1A" ],
    "parents" : [ 10375299, 10375316 ],
    "children" : [ ]
  }, {
    "dbId" : 10333311,
    "stId" : "R-BTA-68806",
    "displayName" : "PSMD7 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48898,
    "identifier" : "Q3ZBD0",
    "standardIdentifier" : "uniprot:Q3ZBD0",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "PSMD7" ],
    "parents" : [ 10333313 ],
    "children" : [ ]
  }, {
    "dbId" : 10375293,
    "stId" : "R-BTA-1234119",
    "displayName" : "EPAS1 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48898,
    "diagramIds" : [ 63547 ],
    "identifier" : "A5PJT1",
    "standardIdentifier" : "uniprot:A5PJT1",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "EPAS1" ],
    "parents" : [ 10375299, 10375316 ],
    "children" : [ ]
  }, {
    "dbId" : 10333305,
    "stId" : "R-BTA-9907947",
    "displayName" : "PSMC2:PSMC1 [cytosol]",
    "schemaClass" : "Complex",
    "speciesId" : 48898,
    "parents" : [ 10333307 ],
    "children" : [ 10333303, 10333301 ]
  }, {
    "dbId" : 10332793,
    "stId" : "R-BTA-939849",
    "displayName" : "UBB [nucleoplasm]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48898,
    "identifier" : "P0CG53",
    "standardIdentifier" : "uniprot:P0CG53",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "UBB" ],
    "parents" : [ 10332827 ],
    "children" : [ ]
  }, {
    "dbId" : 10333307,
    "stId" : "R-BTA-9908171",
    "displayName" : "PSMC2:PSMC1:PSMD2 [cytosol]",
    "schemaClass" : "Complex",
    "speciesId" : 48898,
    "parents" : [ 10333309 ],
    "children" : [ 9918586, 10333305 ]
  }, {
    "dbId" : 10375289,
    "stId" : "R-BTA-8932481",
    "displayName" : "VBC complex (with or without LIMD1) [cytosol]",
    "schemaClass" : "DefinedSet",
    "speciesId" : 48898,
    "diagramIds" : [ 63510 ],
    "parents" : [ ],
    "children" : [ 10375283, 10373237 ]
  }, {
    "dbId" : 10333301,
    "stId" : "R-BTA-68768",
    "displayName" : "PSMC1 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48898,
    "identifier" : "A4FUZ3",
    "standardIdentifier" : "uniprot:A4FUZ3",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "PSMC1" ],
    "parents" : [ 10333305 ],
    "children" : [ ]
  }, {
    "dbId" : 10375287,
    "stId" : "R-BTA-8932465",
    "displayName" : "ub-hydroxyPro-HIF-alpha:VCB (with or without LIMD1) [cytosol]",
    "schemaClass" : "DefinedSet",
    "speciesId" : 48898,
    "diagramIds" : [ 63508 ],
    "parents" : [ ],
    "children" : [ 10375285, 10375253 ]
  }, {
    "dbId" : 10333303,
    "stId" : "R-BTA-68771",
    "displayName" : "PSMC2 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48898,
    "identifier" : "Q5E9F9",
    "standardIdentifier" : "uniprot:Q5E9F9",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "PSMC2" ],
    "parents" : [ 10333305 ],
    "children" : [ ]
  }, {
    "dbId" : 9918589,
    "stId" : "R-BTA-9918589",
    "displayName" : "bADRM1 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48898,
    "identifier" : "A1L5A6",
    "standardIdentifier" : "uniprot:A1L5A6",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "ADRM1" ],
    "parents" : [ 10333309 ],
    "children" : [ ]
  }, {
    "dbId" : 10373237,
    "stId" : "R-BTA-976093",
    "displayName" : "RBX1-CUL2-EloB,C-VHL [cytosol]",
    "schemaClass" : "Complex",
    "speciesId" : 48898,
    "parents" : [ 10375289, 10375253, 10375283 ],
    "children" : [ 10373235, 10353936, 10373231 ]
  }, {
    "dbId" : 10375285,
    "stId" : "R-BTA-8932472",
    "displayName" : "ub-hydroxyPro-HIF-alpha:VHL:EloB:EloC:CUL2:RBX1:LIMD1,AJUBA,WTIF:PHD2,3 [cytosol]",
    "schemaClass" : "Complex",
    "speciesId" : 48898,
    "diagramIds" : [ 63506 ],
    "parents" : [ 10375287 ],
    "children" : [ 10375251, 10375283 ]
  }, {
    "dbId" : 10333297,
    "stId" : "R-BTA-9907950",
    "displayName" : "PSMC3:PSMC6 [cytosol]",
    "schemaClass" : "Complex",
    "speciesId" : 48898,
    "parents" : [ 10333309 ],
    "children" : [ 10333295, 10333293 ]
  }, {
    "dbId" : 9918587,
    "stId" : "R-BTA-9918587",
    "displayName" : "bPSMC4:bPSMC5 [cytosol]",
    "schemaClass" : "Complex",
    "speciesId" : 48898,
    "parents" : [ 10333309 ],
    "children" : [ 9918593, 9918599 ]
  }, {
    "dbId" : 10375283,
    "stId" : "R-BTA-8932458",
    "displayName" : "PHD2,3:LIMD1,AJUBA,WTIP:VHL:EloB:EloC:CUL2:RBX1 [cytosol]",
    "schemaClass" : "Complex",
    "speciesId" : 48898,
    "diagramIds" : [ 63496 ],
    "parents" : [ 10375289, 10375285, 10375311 ],
    "children" : [ 10375281, 10375267, 10373237 ]
  }, {
    "dbId" : 10373235,
    "stId" : "R-BTA-416982",
    "displayName" : "CUL2 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48898,
    "identifier" : "Q08DE9",
    "standardIdentifier" : "uniprot:Q08DE9",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "CUL2" ],
    "parents" : [ 10373237 ],
    "children" : [ ]
  }, {
    "dbId" : 9918586,
    "stId" : "R-BTA-9918586",
    "displayName" : "bPSMD2 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48898,
    "identifier" : "P56701",
    "standardIdentifier" : "uniprot:P56701",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "PSMD2", "TRAP2" ],
    "parents" : [ 10333307 ],
    "children" : [ ]
  }, {
    "dbId" : 10333299,
    "stId" : "R-BTA-68786",
    "displayName" : "PSMD1 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48898,
    "identifier" : "A7MBA2",
    "standardIdentifier" : "uniprot:A7MBA2",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "PSMD1" ],
    "parents" : [ 10333309 ],
    "children" : [ ]
  }, {
    "dbId" : 9918585,
    "stId" : "R-BTA-9918585",
    "displayName" : "bPSMD14 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48898,
    "identifier" : "Q17QP9",
    "standardIdentifier" : "uniprot:Q17QP9",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "PSMD14" ],
    "parents" : [ 10333313 ],
    "children" : [ ]
  }, {
    "dbId" : 10375281,
    "stId" : "R-BTA-1234122",
    "displayName" : "PHD2,3 [cytosol]",
    "schemaClass" : "DefinedSet",
    "speciesId" : 48898,
    "parents" : [ 10375283 ],
    "children" : [ 10375273, 10375279 ]
  }, {
    "dbId" : 10333293,
    "stId" : "R-BTA-68774",
    "displayName" : "PSMC3 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48898,
    "identifier" : "F1MWE0",
    "standardIdentifier" : "uniprot:F1MWE0",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "PSMC3" ],
    "parents" : [ 10333297 ],
    "children" : [ ]
  }, {
    "dbId" : 10373231,
    "stId" : "R-BTA-390483",
    "displayName" : "VBC complex [cytosol]",
    "schemaClass" : "Complex",
    "speciesId" : 48898,
    "parents" : [ 10373237 ],
    "children" : [ 10373223, 10373225, 10373229 ]
  }, {
    "dbId" : 10375279,
    "stId" : "R-BTA-9640403",
    "displayName" : "EGLN1:AscH-:Fe2+ [cytosol]",
    "schemaClass" : "Complex",
    "speciesId" : 48898,
    "parents" : [ 10375281 ],
    "children" : [ 71067, 10375277, 198816 ]
  }, {
    "dbId" : 10333295,
    "stId" : "R-BTA-68783",
    "displayName" : "PSMC6 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48898,
    "identifier" : "F1MLV1",
    "standardIdentifier" : "uniprot:F1MLV1",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "PSMC6" ],
    "parents" : [ 10333297 ],
    "children" : [ ]
  }, {
    "dbId" : 10370413,
    "stId" : "R-BTA-381325",
    "displayName" : "EP300 [nucleoplasm]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48898,
    "diagramIds" : [ 63519 ],
    "identifier" : "E1B8D6",
    "standardIdentifier" : "uniprot:E1B8D6",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "EP300" ],
    "parents" : [ 10375356 ],
    "children" : [ ]
  }, {
    "dbId" : 10373229,
    "stId" : "R-BTA-391423",
    "displayName" : "VHL [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48898,
    "identifier" : "E1BL53",
    "standardIdentifier" : "uniprot:E1BL53",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 10373231 ],
    "children" : [ ]
  }, {
    "dbId" : 10375277,
    "stId" : "R-BTA-1234108",
    "displayName" : "EGLN1 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48898,
    "identifier" : "A0A3Q1M2B6",
    "standardIdentifier" : "uniprot:A0A3Q1M2B6",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "EGLN1" ],
    "parents" : [ 10375279 ],
    "children" : [ ]
  }, {
    "dbId" : 29428,
    "stId" : "R-ALL-29428",
    "displayName" : "DNA [nucleoplasm]",
    "schemaClass" : "OtherEntity",
    "speciesId" : 0,
    "diagramIds" : [ 63521 ],
    "parents" : [ 10375356 ],
    "children" : [ ]
  }, {
    "dbId" : 10333291,
    "stId" : "R-BTA-113595",
    "displayName" : "Ub [cytosol]",
    "schemaClass" : "DefinedSet",
    "speciesId" : 48898,
    "diagramIds" : [ 63509 ],
    "parents" : [ 10375251, 10345490 ],
    "children" : [ 10333263, 10333273, 10333265, 10333267 ]
  }, {
    "dbId" : 10373225,
    "stId" : "R-BTA-180551",
    "displayName" : "TCEB2 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48898,
    "identifier" : "Q3SZ32",
    "standardIdentifier" : "uniprot:Q3SZ32",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "TCEB2" ],
    "parents" : [ 10373231 ],
    "children" : [ ]
  }, {
    "dbId" : 10375273,
    "stId" : "R-BTA-9640402",
    "displayName" : "EGLN3:AscH-:Fe2+ [cytosol]",
    "schemaClass" : "Complex",
    "speciesId" : 48898,
    "parents" : [ 10375281 ],
    "children" : [ 71067, 10375271, 198816 ]
  }, {
    "dbId" : 10373223,
    "stId" : "R-BTA-180535",
    "displayName" : "ELOC [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48898,
    "identifier" : "Q2KII4",
    "standardIdentifier" : "uniprot:Q2KII4",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "ELOC" ],
    "parents" : [ 10373231 ],
    "children" : [ ]
  }, {
    "dbId" : 10375271,
    "stId" : "R-BTA-1234115",
    "displayName" : "EGLN3 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48898,
    "identifier" : "A7MBA0",
    "standardIdentifier" : "uniprot:A7MBA0",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "EGLN3" ],
    "parents" : [ 10375273 ],
    "children" : [ ]
  }, {
    "dbId" : 29434,
    "stId" : "R-ALL-29434",
    "displayName" : "SUCCA [cytosol]",
    "schemaClass" : "SimpleEntity",
    "speciesId" : 0,
    "diagramIds" : [ 63495, 63485 ],
    "identifier" : "30031",
    "standardIdentifier" : "chebi:30031",
    "referenceType" : "ReferenceMolecule",
    "parents" : [ ],
    "children" : [ ]
  }, {
    "dbId" : 10375267,
    "stId" : "R-BTA-8932471",
    "displayName" : "LIMD1,AJUBA,WTIP [cytosol]",
    "schemaClass" : "CandidateSet",
    "speciesId" : 48898,
    "parents" : [ 10375283 ],
    "children" : [ 10375257, 10375265, 10375261 ]
  }, {
    "dbId" : 10375265,
    "stId" : "R-BTA-8932477",
    "displayName" : "WTIP [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48898,
    "identifier" : "E1BP33",
    "standardIdentifier" : "uniprot:E1BP33",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "WTIP" ],
    "parents" : [ 10375267 ],
    "children" : [ ]
  } ],
  "edges" : [ {
    "dbId" : 10375291,
    "stId" : "R-BTA-1234159",
    "displayName" : "Proteasome proteolyzes ub-HIF-alpha",
    "schemaClass" : "BlackBoxEvent",
    "speciesId" : 0,
    "preceding" : [ 10375314, 10375401 ],
    "inputs" : [ 10375287 ],
    "outputs" : [ 10375289, 10333291 ],
    "catalysts" : [ 10333339 ],
    "efs" : [ ],
    "diagramIds" : [ 63507 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10375352,
    "stId" : "R-BTA-1234165",
    "displayName" : "Nuclear PHD1,3 hydroxylates proline residues on HIF3A",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "following" : [ 10375381 ],
    "inputs" : [ 10375305, 113671, 113685 ],
    "outputs" : [ 10375337, 159942, 159939 ],
    "catalysts" : [ 10375349 ],
    "efs" : [ ],
    "diagramIds" : [ 63532 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10375383,
    "stId" : "R-BTA-1234171",
    "displayName" : "HIF-alpha binds ARNT (HIF1-beta) forming HIF-alpha:ARNT",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "preceding" : [ 10375309 ],
    "following" : [ 10375362 ],
    "inputs" : [ 10338971, 10375307 ],
    "outputs" : [ 10375354 ],
    "efs" : [ ],
    "diagramIds" : [ 63515 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10375381,
    "stId" : "R-BTA-1234169",
    "displayName" : "Nuclear VHL:EloB,C:CUL2:RBX1 binds hydroxyprolyl-HIF-alpha",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "preceding" : [ 10375352, 10375405 ],
    "following" : [ 10375396 ],
    "inputs" : [ 10375377, 10375369 ],
    "outputs" : [ 10375379 ],
    "efs" : [ ],
    "diagramIds" : [ 63535 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10375314,
    "stId" : "R-BTA-1234163",
    "displayName" : "Cytosolic VBC complex ubiquitinylates hydroxyprolyl-HIF-alpha ",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "preceding" : [ 10375407 ],
    "following" : [ 10375291 ],
    "inputs" : [ 10345490, 10375311 ],
    "outputs" : [ 10345488, 10375285 ],
    "catalysts" : [ 10375311 ],
    "efs" : [ ],
    "diagramIds" : [ 63503 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10375407,
    "stId" : "R-BTA-1234183",
    "displayName" : "Cytosolic VHL:EloB,C:CUL2:RBX1 binds hydroxyprolyl-HIF-alpha ",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "preceding" : [ 10375399, 10375403 ],
    "following" : [ 10375314 ],
    "inputs" : [ 10375249, 10375283 ],
    "outputs" : [ 10375311 ],
    "efs" : [ ],
    "diagramIds" : [ 63500 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10375309,
    "stId" : "R-BTA-1234161",
    "displayName" : "HIF-alpha translocates from cytosol to nucleus",
    "schemaClass" : "BlackBoxEvent",
    "speciesId" : 0,
    "following" : [ 10375383 ],
    "inputs" : [ 10375299 ],
    "outputs" : [ 10375307 ],
    "efs" : [ ],
    "diagramIds" : [ 63512 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10375405,
    "stId" : "R-BTA-1234181",
    "displayName" : "Nuclear PHD1,3 hydroxylates proline residues on HIF1A",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "following" : [ 10375381 ],
    "inputs" : [ 10375303, 113671, 113685 ],
    "outputs" : [ 10375367, 159942, 159939 ],
    "catalysts" : [ 10375349 ],
    "efs" : [ ],
    "diagramIds" : [ 63524 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10375403,
    "stId" : "R-BTA-1234177",
    "displayName" : "Cytosolic PHD2,3 hydroxylates proline residues on HIF1A",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "following" : [ 10375407 ],
    "inputs" : [ 29406, 29368, 10375295 ],
    "outputs" : [ 29434, 113528, 10375242 ],
    "catalysts" : [ 10375283 ],
    "efs" : [ ],
    "diagramIds" : [ 63489 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10375401,
    "stId" : "R-BTA-1234175",
    "displayName" : "ub-hydroxyPro-HIF-alpha:VHL:EloB,C:CUL2:RBX1 translocates from the nucleus to the cytosol",
    "schemaClass" : "BlackBoxEvent",
    "speciesId" : 0,
    "preceding" : [ 10375396 ],
    "following" : [ 10375291 ],
    "inputs" : [ 10375393 ],
    "outputs" : [ 10375253 ],
    "efs" : [ ],
    "diagramIds" : [ 63543 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10375399,
    "stId" : "R-BTA-1234173",
    "displayName" : "Cytosolic PHD2,3 hydroxylates proline residues on HIF3A",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "following" : [ 10375407 ],
    "inputs" : [ 10375297, 29406, 29368 ],
    "outputs" : [ 29434, 113528, 10375247 ],
    "catalysts" : [ 10375283 ],
    "efs" : [ ],
    "diagramIds" : [ 63497 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10375335,
    "stId" : "R-BTA-1234164",
    "displayName" : "Cytosolic HIF1AN (FIH1) hydroxylates asparagine residues of Hypoxia-inducible Factor Alpha (HIF1A,HIF2A)",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "inputs" : [ 29406, 10375316, 29368 ],
    "outputs" : [ 29434, 113528, 10375324 ],
    "catalysts" : [ 10375332 ],
    "efs" : [ ],
    "diagramIds" : [ 63481 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10375396,
    "stId" : "R-BTA-1234172",
    "displayName" : "Nuclear VBC complex ubiquitinylates HIF-alpha",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "preceding" : [ 10375381 ],
    "following" : [ 10375401 ],
    "inputs" : [ 10375379, 10375389 ],
    "outputs" : [ 10375393, 10375387 ],
    "catalysts" : [ 10375379 ],
    "efs" : [ ],
    "diagramIds" : [ 63539 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10375362,
    "stId" : "R-BTA-1234167",
    "displayName" : "Formation of HIF:CBP:p300 complex at promoters",
    "schemaClass" : "BlackBoxEvent",
    "speciesId" : 0,
    "preceding" : [ 10375383 ],
    "inputs" : [ 10354897, 29428, 10375354, 10370413 ],
    "outputs" : [ 10375356 ],
    "efs" : [ ],
    "inhibitors" : [ 10375360 ],
    "diagramIds" : [ 63518 ],
    "entityFunctionalStatus" : [ ]
  } ],
  "subpathways" : [ {
    "dbId" : 10444936,
    "stId" : "R-BTA-1234176",
    "displayName" : "Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha",
    "events" : [ 10375407, 10375405, 10375403, 10375291, 10375352, 10375401, 10375399, 10375396, 10375381, 10375314 ]
  }, {
    "dbId" : 10444940,
    "stId" : "R-BTA-1234158",
    "displayName" : "Regulation of gene expression by Hypoxia-inducible Factor",
    "events" : [ 10375309, 10375383, 10375362 ]
  } ]
}