{ "dbId" : 11129150, "stableId" : "R-PFA-391251", "displayName" : "Protein folding", "nodes" : [ { "id" : 63913, "reactomeId" : 113592, "displayName" : "ATP", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 433, "y" : 840 }, "minX" : 374, "maxX" : 456, "minY" : 828, "maxY" : 868, "prop" : { "x" : 411, "y" : 829, "width" : 44, "height" : 23 }, "textPosition" : { "x" : 417, "y" : 830 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 450, "y" : 834 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 450, "y" : 834 } } }, "connectors" : [ { "edgeId" : 63912, "type" : "INPUT", "segments" : [ { "from" : { "x" : 408, "y" : 850 }, "to" : { "x" : 374, "y" : 868 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 63914, "reactomeId" : 11123629, "displayName" : "Unfolded G-protein beta subunit:CCT/TRiC:ADP", "schemaClass" : "Complex", "renderableClass" : "Complex", "position" : { "x" : 261, "y" : 875 }, "minX" : 197, "maxX" : 374, "minY" : 843, "maxY" : 902, "prop" : { "x" : 197, "y" : 849, "width" : 128, "height" : 53 }, "textPosition" : { "x" : 196, "y" : 853 }, "bgColor" : { "r" : 204, "g" : 255, "b" : 255 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 325, "y" : 849 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 325, "y" : 849 } } }, "connectors" : [ { "edgeId" : 63912, "type" : "INPUT", "segments" : [ { "from" : { "x" : 328, "y" : 871 }, "to" : { "x" : 374, "y" : 868 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 63915, "reactomeId" : 29370, "displayName" : "ADP", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 451, "y" : 895 }, "minX" : 387, "maxX" : 473, "minY" : 882, "maxY" : 908, "prop" : { "x" : 430, "y" : 883, "width" : 42, "height" : 25 }, "textPosition" : { "x" : 434, "y" : 885 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 467, "y" : 888 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 467, "y" : 888 } } }, "connectors" : [ { "edgeId" : 63912, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 427, "y" : 899 }, "to" : { "x" : 387, "y" : 908 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 421, "y" : 904 }, "b" : { "x" : 427, "y" : 899 }, "c" : { "x" : 419, "y" : 897 }, "type" : "ARROW", "centre" : { "x" : 419, "y" : 897 } } } ] }, { "id" : 63916, "reactomeId" : 11123621, "displayName" : "Unfolded G-protein beta subunit:CCT/TRiC:ATP", "schemaClass" : "Complex", "renderableClass" : "Complex", "position" : { "x" : 446, "y" : 963 }, "minX" : 383, "maxX" : 515, "minY" : 908, "maxY" : 988, "prop" : { "x" : 383, "y" : 938, "width" : 126, "height" : 50 }, "textPosition" : { "x" : 381, "y" : 939 }, "bgColor" : { "r" : 204, "g" : 255, "b" : 255 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 509, "y" : 938 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 509, "y" : 938 } } }, "connectors" : [ { "edgeId" : 63912, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 419, "y" : 935 }, "to" : { "x" : 387, "y" : 908 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 411, "y" : 934 }, "b" : { "x" : 419, "y" : 935 }, "c" : { "x" : 416, "y" : 927 }, "type" : "ARROW", "centre" : { "x" : 416, "y" : 927 } } }, { "edgeId" : 63917, "type" : "INPUT", "segments" : [ ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 63918, "reactomeId" : 11123625, "displayName" : "Partially folded G-protein beta subunit:CCT/TRiC:ADP", "schemaClass" : "Complex", "renderableClass" : "Complex", "position" : { "x" : 239, "y" : 956 }, "minX" : 174, "maxX" : 340, "minY" : 918, "maxY" : 988, "prop" : { "x" : 174, "y" : 924, "width" : 130, "height" : 64 }, "textPosition" : { "x" : 180, "y" : 925 }, "bgColor" : { "r" : 204, "g" : 255, "b" : 255 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 304, "y" : 924 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 304, "y" : 924 } } }, "connectors" : [ { "edgeId" : 63917, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 307, "y" : 965 }, "to" : { "x" : 340, "y" : 971 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 315, "y" : 962 }, "b" : { "x" : 307, "y" : 965 }, "c" : { "x" : 313, "y" : 970 }, "type" : "ARROW", "centre" : { "x" : 313, "y" : 970 } } } ] }, { "id" : 63919, "reactomeId" : 29372, "displayName" : "Pi", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 344, "y" : 1006 }, "minX" : 323, "maxX" : 366, "minY" : 971, "maxY" : 1016, "prop" : { "x" : 323, "y" : 996, "width" : 42, "height" : 20 }, "textPosition" : { "x" : 334, "y" : 996 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 360, "y" : 1001 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 360, "y" : 1001 } } }, "connectors" : [ { "edgeId" : 63917, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 342, "y" : 993 }, "to" : { "x" : 340, "y" : 971 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 337, "y" : 986 }, "b" : { "x" : 342, "y" : 993 }, "c" : { "x" : 345, "y" : 986 }, "type" : "ARROW", "centre" : { "x" : 345, "y" : 986 } } } ] } ], "edges" : [ { "id" : 63912, "reactomeId" : 11123631, "displayName" : "ATP binds G-protein beta associated TRiC/CCT", "schemaClass" : "Reaction", "renderableClass" : "Reaction", "position" : { "x" : 383, "y" : 888 }, "minX" : 374, "maxX" : 389, "minY" : 868, "maxY" : 908, "reactionType" : "transition", "segments" : [ { "from" : { "x" : 374, "y" : 868 }, "to" : { "x" : 383, "y" : 888 } }, { "from" : { "x" : 383, "y" : 888 }, "to" : { "x" : 387, "y" : 908 } } ], "reactionShape" : { "a" : { "x" : 377, "y" : 882 }, "b" : { "x" : 389, "y" : 894 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 383, "y" : 888 } }, "inputs" : [ { "id" : 63913, "points" : [ { "x" : 408, "y" : 850 } ] }, { "id" : 63914, "points" : [ { "x" : 328, "y" : 871 } ] } ], "outputs" : [ { "id" : 63915, "points" : [ { "x" : 427, "y" : 899 } ] }, { "id" : 63916, "points" : [ { "x" : 419, "y" : 935 } ] } ] }, { "id" : 63917, "reactomeId" : 11123627, "displayName" : "ATP hydrolysis promotes folding of G-protein beta by TRiC/CCT", "schemaClass" : "Reaction", "renderableClass" : "Reaction", "position" : { "x" : 362, "y" : 968 }, "minX" : 340, "maxX" : 380, "minY" : 962, "maxY" : 974, "reactionType" : "dissociation", "segments" : [ { "from" : { "x" : 380, "y" : 966 }, "to" : { "x" : 362, "y" : 968 } }, { "from" : { "x" : 362, "y" : 968 }, "to" : { "x" : 340, "y" : 971 } } ], "reactionShape" : { "c" : { "x" : 362, "y" : 968 }, "r" : 5, "r1" : 3, "type" : "DOUBLE_CIRCLE", "empty" : true, "centre" : { "x" : 362, "y" : 968 } }, "inputs" : [ { "id" : 63916 } ], "outputs" : [ { "id" : 63918, "points" : [ { "x" : 307, "y" : 965 } ] }, { "id" : 63919, "points" : [ { "x" : 342, "y" : 993 } ] } ] } ], "compartments" : [ { "id" : 63927, "reactomeId" : 70101, "displayName" : "cytosol", "schemaClass" : "Compartment", "renderableClass" : "Compartment", "position" : { "x" : 832, "y" : 671 }, "minX" : 0, "maxX" : 1664, "minY" : 0, "maxY" : 1342, "prop" : { "x" : 0, "y" : 0, "width" : 1664, "height" : 1342 }, "textPosition" : { "x" : 38, "y" : 1064 }, "insets" : { "x" : 10, "y" : 10, "width" : 1644, "height" : 1322 }, "bgColor" : { "r" : 250, "g" : 240, "b" : 240 }, "componentIds" : [ 63914, 63912, 63917, 63919, 63913, 63915, 63916, 63918 ] } ], "notes" : [ ], "links" : [ ], "shadows" : [ { "id" : 63928, "reactomeId" : 11129148, "displayName" : "Chaperonin-mediated protein folding", "schemaClass" : "Pathway", "renderableClass" : "Shadow", "position" : { "x" : 341, "y" : 922 }, "minX" : 164, "maxX" : 519, "minY" : 819, "maxY" : 1026, "prop" : { "x" : 164, "y" : 819, "width" : 355, "height" : 207 }, "points" : [ { "x" : 164, "y" : 819 }, { "x" : 519, "y" : 819 }, { "x" : 519, "y" : 1026 }, { "x" : 164, "y" : 1026 } ], "colour" : "#4684ee" } ], "minX" : 0, "maxX" : 1664, "minY" : 0, "maxY" : 1342, "disease" : false }