{
  "dbId" : 11128122,
  "stableId" : "R-PFA-9856872",
  "displayName" : "Malate-aspartate shuttle",
  "nodes" : [ {
    "id" : 51043,
    "reactomeId" : 11128112,
    "displayName" : "Glucose metabolism",
    "schemaClass" : "Pathway",
    "renderableClass" : "EncapsulatedNode",
    "position" : {
      "x" : 74,
      "y" : 70
    },
    "minX" : 26,
    "maxX" : 123,
    "minY" : 44,
    "maxY" : 96,
    "prop" : {
      "x" : 26,
      "y" : 44,
      "width" : 97,
      "height" : 52
    },
    "textPosition" : {
      "x" : 30,
      "y" : 48
    },
    "connectors" : [ ]
  }, {
    "id" : 51044,
    "reactomeId" : 11128134,
    "displayName" : "Citric acid cycle (TCA cycle)",
    "schemaClass" : "Pathway",
    "renderableClass" : "EncapsulatedNode",
    "position" : {
      "x" : 1040,
      "y" : 438
    },
    "minX" : 946,
    "maxX" : 1134,
    "minY" : 412,
    "maxY" : 465,
    "prop" : {
      "x" : 946,
      "y" : 412,
      "width" : 188,
      "height" : 53
    },
    "textPosition" : {
      "x" : 948,
      "y" : 424
    },
    "connectors" : [ ]
  }, {
    "id" : 51017,
    "reactomeId" : 113587,
    "displayName" : "OA",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 673,
      "y" : 328
    },
    "minX" : 609,
    "maxX" : 743,
    "minY" : 264,
    "maxY" : 421,
    "prop" : {
      "x" : 655,
      "y" : 313,
      "width" : 36,
      "height" : 30
    },
    "textPosition" : {
      "x" : 660,
      "y" : 317
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 686,
          "y" : 318
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 686,
          "y" : 318
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 51016,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 658,
          "y" : 310
        },
        "to" : {
          "x" : 609,
          "y" : 264
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 51022,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 684,
          "y" : 346
        },
        "to" : {
          "x" : 743,
          "y" : 421
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 691,
          "y" : 349
        },
        "b" : {
          "x" : 684,
          "y" : 346
        },
        "c" : {
          "x" : 685,
          "y" : 354
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 685,
          "y" : 354
        }
      }
    } ]
  }, {
    "id" : 51018,
    "reactomeId" : 113552,
    "displayName" : "L-Glu",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 520,
      "y" : 296
    },
    "minX" : 501,
    "maxX" : 609,
    "minY" : 264,
    "maxY" : 312,
    "prop" : {
      "x" : 501,
      "y" : 280,
      "width" : 39,
      "height" : 32
    },
    "textPosition" : {
      "x" : 501,
      "y" : 285
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 535,
          "y" : 285
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 535,
          "y" : 285
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 51016,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 543,
          "y" : 288
        },
        "to" : {
          "x" : 609,
          "y" : 264
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 51019,
    "reactomeId" : 113594,
    "displayName" : "2OG",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 644,
      "y" : 150
    },
    "minX" : 412,
    "maxX" : 919,
    "minY" : 133,
    "maxY" : 587,
    "prop" : {
      "x" : 624,
      "y" : 134,
      "width" : 40,
      "height" : 32
    },
    "textPosition" : {
      "x" : 627,
      "y" : 139
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 659,
          "y" : 139
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 659,
          "y" : 139
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 51028,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 667,
          "y" : 159
        },
        "to" : {
          "x" : 919,
          "y" : 276
        }
      }, {
        "from" : {
          "x" : 919,
          "y" : 276
        },
        "to" : {
          "x" : 918,
          "y" : 587
        }
      }, {
        "from" : {
          "x" : 918,
          "y" : 587
        },
        "to" : {
          "x" : 412,
          "y" : 508
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 51016,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 633,
          "y" : 169
        },
        "to" : {
          "x" : 610,
          "y" : 202
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 632,
          "y" : 177
        },
        "b" : {
          "x" : 633,
          "y" : 169
        },
        "c" : {
          "x" : 626,
          "y" : 172
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 626,
          "y" : 172
        }
      }
    } ]
  }, {
    "id" : 51020,
    "reactomeId" : 113553,
    "displayName" : "L-Asp",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 554,
      "y" : 147
    },
    "minX" : 529,
    "maxX" : 610,
    "minY" : 130,
    "maxY" : 202,
    "prop" : {
      "x" : 529,
      "y" : 131,
      "width" : 50,
      "height" : 33
    },
    "textPosition" : {
      "x" : 533,
      "y" : 137
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 574,
          "y" : 136
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 574,
          "y" : 136
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 51016,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 570,
          "y" : 167
        },
        "to" : {
          "x" : 610,
          "y" : 202
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 578,
          "y" : 169
        },
        "b" : {
          "x" : 570,
          "y" : 167
        },
        "c" : {
          "x" : 573,
          "y" : 175
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 573,
          "y" : 175
        }
      }
    } ]
  }, {
    "id" : 51021,
    "reactomeId" : 11109460,
    "displayName" : "GOT2 dimer",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 690,
      "y" : 230
    },
    "minX" : 618,
    "maxX" : 719,
    "minY" : 206,
    "maxY" : 249,
    "prop" : {
      "x" : 668,
      "y" : 212,
      "width" : 45,
      "height" : 37
    },
    "textPosition" : {
      "x" : 668,
      "y" : 214
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 713,
          "y" : 212
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 713,
          "y" : 212
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 51016,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 665,
          "y" : 230
        },
        "to" : {
          "x" : 626,
          "y" : 231
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 622,
          "y" : 232
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 622,
          "y" : 232
        }
      }
    } ]
  }, {
    "id" : 51023,
    "reactomeId" : 113526,
    "displayName" : "NAD+",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 795,
      "y" : 523
    },
    "minX" : 745,
    "maxX" : 820,
    "minY" : 469,
    "maxY" : 542,
    "prop" : {
      "x" : 771,
      "y" : 505,
      "width" : 48,
      "height" : 37
    },
    "textPosition" : {
      "x" : 773,
      "y" : 513
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 814,
          "y" : 510
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 814,
          "y" : 510
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 51022,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 777,
          "y" : 502
        },
        "to" : {
          "x" : 745,
          "y" : 469
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 51024,
    "reactomeId" : 113544,
    "displayName" : "MAL",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 675,
      "y" : 511
    },
    "minX" : 412,
    "maxX" : 745,
    "minY" : 469,
    "maxY" : 531,
    "prop" : {
      "x" : 652,
      "y" : 492,
      "width" : 47,
      "height" : 39
    },
    "textPosition" : {
      "x" : 659,
      "y" : 501
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 694,
          "y" : 497
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 694,
          "y" : 497
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 51028,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 649,
          "y" : 510
        },
        "to" : {
          "x" : 412,
          "y" : 508
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 642,
          "y" : 514
        },
        "b" : {
          "x" : 649,
          "y" : 510
        },
        "c" : {
          "x" : 642,
          "y" : 506
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 642,
          "y" : 506
        }
      }
    }, {
      "edgeId" : 51022,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 702,
          "y" : 496
        },
        "to" : {
          "x" : 745,
          "y" : 469
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 51025,
    "reactomeId" : 113529,
    "displayName" : "H+",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 775,
      "y" : 325
    },
    "minX" : 743,
    "maxX" : 792,
    "minY" : 309,
    "maxY" : 421,
    "prop" : {
      "x" : 759,
      "y" : 310,
      "width" : 32,
      "height" : 31
    },
    "textPosition" : {
      "x" : 761,
      "y" : 315
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 786,
          "y" : 315
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 786,
          "y" : 315
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 51022,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 769,
          "y" : 344
        },
        "to" : {
          "x" : 743,
          "y" : 421
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 771,
          "y" : 352
        },
        "b" : {
          "x" : 769,
          "y" : 344
        },
        "c" : {
          "x" : 763,
          "y" : 349
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 763,
          "y" : 349
        }
      }
    } ],
    "trivial" : true
  }, {
    "id" : 51026,
    "reactomeId" : 29362,
    "displayName" : "NADH",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 832,
      "y" : 378
    },
    "minX" : 743,
    "maxX" : 855,
    "minY" : 359,
    "maxY" : 421,
    "prop" : {
      "x" : 810,
      "y" : 360,
      "width" : 44,
      "height" : 36
    },
    "textPosition" : {
      "x" : 810,
      "y" : 367
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 849,
          "y" : 365
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 849,
          "y" : 365
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 51022,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 807,
          "y" : 388
        },
        "to" : {
          "x" : 743,
          "y" : 421
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 803,
          "y" : 395
        },
        "b" : {
          "x" : 807,
          "y" : 388
        },
        "c" : {
          "x" : 799,
          "y" : 388
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 799,
          "y" : 388
        }
      }
    } ]
  }, {
    "id" : 51027,
    "reactomeId" : 11109556,
    "displayName" : "MDH2 dimer",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 815,
      "y" : 445
    },
    "minX" : 751,
    "maxX" : 845,
    "minY" : 421,
    "maxY" : 463,
    "prop" : {
      "x" : 792,
      "y" : 427,
      "width" : 47,
      "height" : 36
    },
    "textPosition" : {
      "x" : 792,
      "y" : 428
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 839,
          "y" : 427
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 839,
          "y" : 427
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 51022,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 789,
          "y" : 445
        },
        "to" : {
          "x" : 759,
          "y" : 446
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 755,
          "y" : 446
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 755,
          "y" : 446
        }
      }
    } ]
  }, {
    "id" : 51029,
    "reactomeId" : 198498,
    "displayName" : "MAL",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 168,
      "y" : 508
    },
    "minX" : 148,
    "maxX" : 412,
    "minY" : 491,
    "maxY" : 524,
    "prop" : {
      "x" : 148,
      "y" : 492,
      "width" : 40,
      "height" : 32
    },
    "textPosition" : {
      "x" : 152,
      "y" : 497
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 183,
          "y" : 497
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 183,
          "y" : 497
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 51028,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 191,
          "y" : 508
        },
        "to" : {
          "x" : 412,
          "y" : 508
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 51030,
    "reactomeId" : 29406,
    "displayName" : "2OG",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 220,
      "y" : 123
    },
    "minX" : 0,
    "maxX" : 412,
    "minY" : 106,
    "maxY" : 559,
    "prop" : {
      "x" : 201,
      "y" : 107,
      "width" : 38,
      "height" : 32
    },
    "textPosition" : {
      "x" : 203,
      "y" : 112
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 234,
          "y" : 112
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 234,
          "y" : 112
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 51028,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 198,
          "y" : 133
        },
        "to" : {
          "x" : 0,
          "y" : 249
        }
      }, {
        "from" : {
          "x" : 0,
          "y" : 249
        },
        "to" : {
          "x" : 0,
          "y" : 559
        }
      }, {
        "from" : {
          "x" : 0,
          "y" : 559
        },
        "to" : {
          "x" : 412,
          "y" : 508
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 194,
          "y" : 140
        },
        "b" : {
          "x" : 198,
          "y" : 133
        },
        "c" : {
          "x" : 190,
          "y" : 133
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 190,
          "y" : 133
        }
      }
    } ]
  }, {
    "id" : 51031,
    "reactomeId" : 11112576,
    "displayName" : "SLC25A11 homodimer",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 409,
      "y" : 572
    },
    "minX" : 370,
    "maxX" : 454,
    "minY" : 516,
    "maxY" : 590,
    "prop" : {
      "x" : 370,
      "y" : 555,
      "width" : 78,
      "height" : 35
    },
    "textPosition" : {
      "x" : 370,
      "y" : 555
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 448,
          "y" : 555
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 448,
          "y" : 555
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 51028,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 409,
          "y" : 552
        },
        "to" : {
          "x" : 409,
          "y" : 524
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 409,
          "y" : 520
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 409,
          "y" : 520
        }
      }
    } ]
  }, {
    "id" : 51035,
    "reactomeId" : 73473,
    "displayName" : "NADH",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 73,
      "y" : 312
    },
    "minX" : 51,
    "maxX" : 97,
    "minY" : 293,
    "maxY" : 331,
    "prop" : {
      "x" : 51,
      "y" : 294,
      "width" : 45,
      "height" : 37
    },
    "textPosition" : {
      "x" : 52,
      "y" : 302
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 91,
          "y" : 299
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 91,
          "y" : 299
        }
      }
    },
    "connectors" : [ ]
  } ],
  "edges" : [ {
    "id" : 51028,
    "reactomeId" : 11113254,
    "displayName" : "SLC25A11 exchanges 2-OG and MAL",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 409,
      "y" : 508
    },
    "minX" : 403,
    "maxX" : 415,
    "minY" : 502,
    "maxY" : 514,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 412,
        "y" : 508
      },
      "to" : {
        "x" : 409,
        "y" : 508
      }
    }, {
      "from" : {
        "x" : 409,
        "y" : 508
      },
      "to" : {
        "x" : 412,
        "y" : 508
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 403,
        "y" : 502
      },
      "b" : {
        "x" : 415,
        "y" : 514
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 409,
        "y" : 508
      }
    },
    "inputs" : [ {
      "id" : 51029,
      "points" : [ {
        "x" : 191,
        "y" : 508
      } ]
    }, {
      "id" : 51019,
      "points" : [ {
        "x" : 667,
        "y" : 159
      }, {
        "x" : 919,
        "y" : 276
      }, {
        "x" : 918,
        "y" : 587
      } ]
    } ],
    "outputs" : [ {
      "id" : 51024,
      "points" : [ {
        "x" : 649,
        "y" : 510
      } ]
    }, {
      "id" : 51030,
      "points" : [ {
        "x" : 198,
        "y" : 133
      }, {
        "x" : 0,
        "y" : 249
      }, {
        "x" : 0,
        "y" : 559
      } ]
    } ],
    "catalysts" : [ {
      "id" : 51031,
      "points" : [ {
        "x" : 409,
        "y" : 552
      } ]
    } ]
  }, {
    "id" : 51016,
    "reactomeId" : 11109475,
    "displayName" : "GOT2 transaminates OA and L-Glu",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 610,
      "y" : 232
    },
    "minX" : 604,
    "maxX" : 616,
    "minY" : 202,
    "maxY" : 264,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 609,
        "y" : 264
      },
      "to" : {
        "x" : 610,
        "y" : 232
      }
    }, {
      "from" : {
        "x" : 610,
        "y" : 232
      },
      "to" : {
        "x" : 610,
        "y" : 202
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 604,
        "y" : 226
      },
      "b" : {
        "x" : 616,
        "y" : 238
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 610,
        "y" : 232
      }
    },
    "inputs" : [ {
      "id" : 51017,
      "points" : [ {
        "x" : 658,
        "y" : 310
      } ]
    }, {
      "id" : 51018,
      "points" : [ {
        "x" : 543,
        "y" : 288
      } ]
    } ],
    "outputs" : [ {
      "id" : 51019,
      "points" : [ {
        "x" : 633,
        "y" : 169
      } ]
    }, {
      "id" : 51020,
      "points" : [ {
        "x" : 570,
        "y" : 167
      } ]
    } ],
    "catalysts" : [ {
      "id" : 51021,
      "points" : [ {
        "x" : 665,
        "y" : 230
      } ]
    } ]
  }, {
    "id" : 51022,
    "reactomeId" : 11109559,
    "displayName" : "MDH2 dimer dehydrogenates MAL",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 743,
      "y" : 446
    },
    "minX" : 737,
    "maxX" : 749,
    "minY" : 421,
    "maxY" : 469,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 745,
        "y" : 469
      },
      "to" : {
        "x" : 743,
        "y" : 446
      }
    }, {
      "from" : {
        "x" : 743,
        "y" : 446
      },
      "to" : {
        "x" : 743,
        "y" : 421
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 737,
        "y" : 440
      },
      "b" : {
        "x" : 749,
        "y" : 452
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 743,
        "y" : 446
      }
    },
    "inputs" : [ {
      "id" : 51023,
      "points" : [ {
        "x" : 777,
        "y" : 502
      } ]
    }, {
      "id" : 51024,
      "points" : [ {
        "x" : 702,
        "y" : 496
      } ]
    } ],
    "outputs" : [ {
      "id" : 51017,
      "points" : [ {
        "x" : 684,
        "y" : 346
      } ]
    }, {
      "id" : 51025,
      "points" : [ {
        "x" : 769,
        "y" : 344
      } ]
    }, {
      "id" : 51026,
      "points" : [ {
        "x" : 807,
        "y" : 388
      } ]
    } ],
    "catalysts" : [ {
      "id" : 51027,
      "points" : [ {
        "x" : 789,
        "y" : 445
      } ]
    } ]
  } ],
  "compartments" : [ {
    "id" : 51038,
    "reactomeId" : 5460,
    "displayName" : "mitochondrial matrix",
    "schemaClass" : "Compartment",
    "renderableClass" : "Compartment",
    "position" : {
      "x" : 877,
      "y" : 342
    },
    "minX" : 406,
    "maxX" : 1348,
    "minY" : 0,
    "maxY" : 684,
    "prop" : {
      "x" : 406,
      "y" : 0,
      "width" : 942,
      "height" : 684
    },
    "textPosition" : {
      "x" : 716,
      "y" : 110
    },
    "insets" : {
      "x" : 416,
      "y" : 10,
      "width" : 922,
      "height" : 664
    },
    "bgColor" : {
      "r" : 250,
      "g" : 240,
      "b" : 240
    },
    "componentIds" : [ 51018, 51022, 51023, 51017, 51025, 51027, 51019, 51024, 51016, 51020, 51021, 51026, 51031, 51028, 51044, 51049, 51050 ]
  } ],
  "notes" : [ ],
  "links" : [ {
    "id" : 51045,
    "renderableClass" : "Interaction",
    "position" : {
      "x" : 162,
      "y" : 101
    },
    "minX" : 126,
    "maxX" : 198,
    "minY" : 87,
    "maxY" : 115,
    "interactionType" : "Activate",
    "segments" : [ {
      "from" : {
        "x" : 198,
        "y" : 115
      },
      "to" : {
        "x" : 126,
        "y" : 87
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 134,
        "y" : 86
      },
      "b" : {
        "x" : 126,
        "y" : 87
      },
      "c" : {
        "x" : 131,
        "y" : 93
      },
      "type" : "ARROW",
      "empty" : true,
      "centre" : {
        "x" : 131,
        "y" : 93
      }
    },
    "reactionShape" : {
      "a" : {
        "x" : 156,
        "y" : 95
      },
      "b" : {
        "x" : 168,
        "y" : 107
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 162,
        "y" : 101
      }
    },
    "inputs" : [ {
      "id" : 51030
    } ],
    "outputs" : [ {
      "id" : 51043
    } ]
  }, {
    "id" : 51046,
    "renderableClass" : "Interaction",
    "position" : {
      "x" : 73,
      "y" : 195
    },
    "minX" : 67,
    "maxX" : 79,
    "minY" : 99,
    "maxY" : 291,
    "interactionType" : "Activate",
    "segments" : [ {
      "from" : {
        "x" : 73,
        "y" : 99
      },
      "to" : {
        "x" : 73,
        "y" : 291
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 69,
        "y" : 284
      },
      "b" : {
        "x" : 73,
        "y" : 291
      },
      "c" : {
        "x" : 77,
        "y" : 284
      },
      "type" : "ARROW",
      "empty" : true,
      "centre" : {
        "x" : 77,
        "y" : 284
      }
    },
    "reactionShape" : {
      "a" : {
        "x" : 67,
        "y" : 189
      },
      "b" : {
        "x" : 79,
        "y" : 201
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 73,
        "y" : 195
      }
    },
    "inputs" : [ {
      "id" : 51043
    } ],
    "outputs" : [ {
      "id" : 51035
    } ]
  }, {
    "id" : 51049,
    "renderableClass" : "Interaction",
    "position" : {
      "x" : 836,
      "y" : 589
    },
    "minX" : 675,
    "maxX" : 1033,
    "minY" : 468,
    "maxY" : 614,
    "interactionType" : "Activate",
    "segments" : [ {
      "from" : {
        "x" : 1033,
        "y" : 468
      },
      "to" : {
        "x" : 997,
        "y" : 614
      }
    }, {
      "from" : {
        "x" : 997,
        "y" : 614
      },
      "to" : {
        "x" : 675,
        "y" : 564
      }
    }, {
      "from" : {
        "x" : 675,
        "y" : 564
      },
      "to" : {
        "x" : 675,
        "y" : 534
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 679,
        "y" : 541
      },
      "b" : {
        "x" : 675,
        "y" : 534
      },
      "c" : {
        "x" : 671,
        "y" : 541
      },
      "type" : "ARROW",
      "empty" : true,
      "centre" : {
        "x" : 671,
        "y" : 541
      }
    },
    "reactionShape" : {
      "a" : {
        "x" : 830,
        "y" : 583
      },
      "b" : {
        "x" : 842,
        "y" : 595
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 836,
        "y" : 589
      }
    },
    "inputs" : [ {
      "id" : 51044
    } ],
    "outputs" : [ {
      "id" : 51024
    } ]
  }, {
    "id" : 51050,
    "renderableClass" : "Interaction",
    "position" : {
      "x" : 865,
      "y" : 327
    },
    "minX" : 694,
    "maxX" : 1022,
    "minY" : 280,
    "maxY" : 409,
    "interactionType" : "Activate",
    "segments" : [ {
      "from" : {
        "x" : 694,
        "y" : 313
      },
      "to" : {
        "x" : 733,
        "y" : 280
      }
    }, {
      "from" : {
        "x" : 733,
        "y" : 280
      },
      "to" : {
        "x" : 997,
        "y" : 374
      }
    }, {
      "from" : {
        "x" : 997,
        "y" : 374
      },
      "to" : {
        "x" : 1022,
        "y" : 409
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 1015,
        "y" : 406
      },
      "b" : {
        "x" : 1022,
        "y" : 409
      },
      "c" : {
        "x" : 1021,
        "y" : 401
      },
      "type" : "ARROW",
      "empty" : true,
      "centre" : {
        "x" : 1021,
        "y" : 401
      }
    },
    "reactionShape" : {
      "a" : {
        "x" : 859,
        "y" : 321
      },
      "b" : {
        "x" : 871,
        "y" : 333
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 865,
        "y" : 327
      }
    },
    "inputs" : [ {
      "id" : 51017
    } ],
    "outputs" : [ {
      "id" : 51044
    } ]
  } ],
  "shadows" : [ ],
  "minX" : 0,
  "maxX" : 1348,
  "minY" : 0,
  "maxY" : 684,
  "disease" : false
}