{
  "dbId" : 11108000,
  "stableId" : "R-SCE-6806003",
  "displayName" : "Regulation of TP53 Expression and Degradation",
  "nodes" : [ {
    "id" : 44678,
    "reactomeId" : 11086330,
    "displayName" : "p-T,p-S-AKT",
    "schemaClass" : "CandidateSet",
    "renderableClass" : "EntitySet",
    "position" : {
      "x" : 981,
      "y" : 197
    },
    "minX" : 937,
    "maxX" : 1025,
    "minY" : 186,
    "maxY" : 209,
    "prop" : {
      "x" : 937,
      "y" : 186,
      "width" : 88,
      "height" : 23
    },
    "textPosition" : {
      "x" : 942,
      "y" : 187
    },
    "connectors" : [ ]
  }, {
    "id" : 44679,
    "reactomeId" : 11107250,
    "displayName" : "PIP3 activates AKT signaling",
    "schemaClass" : "Pathway",
    "renderableClass" : "EncapsulatedNode",
    "position" : {
      "x" : 677,
      "y" : 63
    },
    "minX" : 604,
    "maxX" : 751,
    "minY" : 37,
    "maxY" : 89,
    "prop" : {
      "x" : 604,
      "y" : 37,
      "width" : 147,
      "height" : 52
    },
    "textPosition" : {
      "x" : 610,
      "y" : 41
    },
    "connectors" : [ ]
  }, {
    "id" : 44680,
    "reactomeId" : 11096547,
    "displayName" : "phospho-MEC1",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 1446,
      "y" : 683
    },
    "minX" : 1346,
    "maxX" : 1552,
    "minY" : 662,
    "maxY" : 699,
    "prop" : {
      "x" : 1346,
      "y" : 668,
      "width" : 200,
      "height" : 31
    },
    "textPosition" : {
      "x" : 1395,
      "y" : 673
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1546,
          "y" : 668
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1546,
          "y" : 668
        }
      }
    },
    "connectors" : [ ]
  }, {
    "id" : 44681,
    "reactomeId" : 11080809,
    "displayName" : "phospho-p-S,3T-CHEK2",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 1431,
      "y" : 1124
    },
    "minX" : 1375,
    "maxX" : 1494,
    "minY" : 1101,
    "maxY" : 1141,
    "prop" : {
      "x" : 1375,
      "y" : 1107,
      "width" : 113,
      "height" : 34
    },
    "textPosition" : {
      "x" : 1376,
      "y" : 1107
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1488,
          "y" : 1107
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1488,
          "y" : 1107
        }
      }
    },
    "connectors" : [ ]
  }, {
    "id" : 44682,
    "reactomeId" : 11106870,
    "displayName" : "DNA Double Strand Break Response",
    "schemaClass" : "Pathway",
    "renderableClass" : "EncapsulatedNode",
    "position" : {
      "x" : 1443,
      "y" : 924
    },
    "minX" : 1372,
    "maxX" : 1514,
    "minY" : 886,
    "maxY" : 963,
    "prop" : {
      "x" : 1372,
      "y" : 886,
      "width" : 142,
      "height" : 77
    },
    "textPosition" : {
      "x" : 1373,
      "y" : 903
    },
    "connectors" : [ ]
  }, {
    "id" : 44657,
    "reactomeId" : 11098775,
    "displayName" : "Homologues of SGK1",
    "schemaClass" : "DefinedSet",
    "renderableClass" : "EntitySet",
    "position" : {
      "x" : 299,
      "y" : 219
    },
    "minX" : 279,
    "maxX" : 355,
    "minY" : 208,
    "maxY" : 230,
    "prop" : {
      "x" : 279,
      "y" : 208,
      "width" : 40,
      "height" : 22
    },
    "textPosition" : {
      "x" : 279,
      "y" : 181
    },
    "connectors" : [ {
      "edgeId" : 44656,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 322,
          "y" : 219
        },
        "to" : {
          "x" : 355,
          "y" : 221
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 44658,
    "reactomeId" : 113592,
    "displayName" : "ATP",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 329,
      "y" : 258
    },
    "minX" : 311,
    "maxX" : 355,
    "minY" : 221,
    "maxY" : 270,
    "prop" : {
      "x" : 311,
      "y" : 247,
      "width" : 37,
      "height" : 23
    },
    "textPosition" : {
      "x" : 314,
      "y" : 248
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 343,
          "y" : 252
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 343,
          "y" : 252
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 44656,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 337,
          "y" : 244
        },
        "to" : {
          "x" : 355,
          "y" : 221
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 44659,
    "reactomeId" : 11098783,
    "displayName" : "Homologues of p-S422-SGK1",
    "schemaClass" : "DefinedSet",
    "renderableClass" : "EntitySet",
    "position" : {
      "x" : 517,
      "y" : 225
    },
    "minX" : 421,
    "maxX" : 619,
    "minY" : 210,
    "maxY" : 241,
    "prop" : {
      "x" : 469,
      "y" : 210,
      "width" : 97,
      "height" : 31
    },
    "textPosition" : {
      "x" : 472,
      "y" : 201
    },
    "connectors" : [ {
      "edgeId" : 44656,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 466,
          "y" : 222
        },
        "to" : {
          "x" : 421,
          "y" : 220
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 459,
          "y" : 226
        },
        "b" : {
          "x" : 466,
          "y" : 222
        },
        "c" : {
          "x" : 459,
          "y" : 218
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 459,
          "y" : 218
        }
      }
    }, {
      "edgeId" : 44662,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 569,
          "y" : 223
        },
        "to" : {
          "x" : 619,
          "y" : 221
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 44660,
    "reactomeId" : 29370,
    "displayName" : "ADP",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 439,
      "y" : 254
    },
    "minX" : 419,
    "maxX" : 460,
    "minY" : 220,
    "maxY" : 265,
    "prop" : {
      "x" : 419,
      "y" : 244,
      "width" : 40,
      "height" : 21
    },
    "textPosition" : {
      "x" : 422,
      "y" : 244
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 454,
          "y" : 249
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 454,
          "y" : 249
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 44656,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 433,
          "y" : 241
        },
        "to" : {
          "x" : 421,
          "y" : 220
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 426,
          "y" : 237
        },
        "b" : {
          "x" : 433,
          "y" : 241
        },
        "c" : {
          "x" : 433,
          "y" : 233
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 433,
          "y" : 233
        }
      }
    } ]
  }, {
    "id" : 44661,
    "reactomeId" : 11086217,
    "displayName" : "mTORC2:PIP3",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 389,
      "y" : 134
    },
    "minX" : 346,
    "maxX" : 438,
    "minY" : 117,
    "maxY" : 211,
    "prop" : {
      "x" : 346,
      "y" : 123,
      "width" : 86,
      "height" : 23
    },
    "textPosition" : {
      "x" : 357,
      "y" : 111
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 432,
          "y" : 123
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 432,
          "y" : 123
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 44656,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 389,
          "y" : 149
        },
        "to" : {
          "x" : 390,
          "y" : 203
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 390,
          "y" : 207
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 390,
          "y" : 207
        }
      }
    } ]
  }, {
    "id" : 44694,
    "reactomeId" : 11108032,
    "displayName" : "Regulation of TP53 Activity through Phosphorylation",
    "schemaClass" : "Pathway",
    "renderableClass" : "EncapsulatedNode",
    "position" : {
      "x" : 450,
      "y" : 996
    },
    "minX" : 381,
    "maxX" : 520,
    "minY" : 962,
    "maxY" : 1031,
    "prop" : {
      "x" : 381,
      "y" : 962,
      "width" : 139,
      "height" : 69
    },
    "textPosition" : {
      "x" : 381,
      "y" : 968
    },
    "connectors" : [ ]
  }, {
    "id" : 44663,
    "reactomeId" : 113592,
    "displayName" : "ATP",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 589,
      "y" : 259
    },
    "minX" : 568,
    "maxX" : 619,
    "minY" : 221,
    "maxY" : 270,
    "prop" : {
      "x" : 568,
      "y" : 249,
      "width" : 43,
      "height" : 21
    },
    "textPosition" : {
      "x" : 574,
      "y" : 249
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 606,
          "y" : 254
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 606,
          "y" : 254
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 44662,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 597,
          "y" : 246
        },
        "to" : {
          "x" : 619,
          "y" : 221
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 44664,
    "reactomeId" : 11098793,
    "displayName" : "Homologues of p-T256,S422-SGK1",
    "schemaClass" : "DefinedSet",
    "renderableClass" : "EntitySet",
    "position" : {
      "x" : 818,
      "y" : 243
    },
    "minX" : 719,
    "maxX" : 886,
    "minY" : 226,
    "maxY" : 256,
    "prop" : {
      "x" : 750,
      "y" : 231,
      "width" : 136,
      "height" : 25
    },
    "textPosition" : {
      "x" : 759,
      "y" : 226
    },
    "connectors" : [ {
      "edgeId" : 44662,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 747,
          "y" : 231
        },
        "to" : {
          "x" : 719,
          "y" : 226
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 739,
          "y" : 234
        },
        "b" : {
          "x" : 747,
          "y" : 231
        },
        "c" : {
          "x" : 741,
          "y" : 226
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 741,
          "y" : 226
        }
      }
    } ]
  }, {
    "id" : 44665,
    "reactomeId" : 29370,
    "displayName" : "ADP",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 734,
      "y" : 283
    },
    "minX" : 713,
    "maxX" : 757,
    "minY" : 226,
    "maxY" : 295,
    "prop" : {
      "x" : 713,
      "y" : 272,
      "width" : 43,
      "height" : 23
    },
    "textPosition" : {
      "x" : 718,
      "y" : 273
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 751,
          "y" : 277
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 751,
          "y" : 277
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 44662,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 730,
          "y" : 269
        },
        "to" : {
          "x" : 719,
          "y" : 226
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 724,
          "y" : 263
        },
        "b" : {
          "x" : 730,
          "y" : 269
        },
        "c" : {
          "x" : 732,
          "y" : 261
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 732,
          "y" : 261
        }
      }
    } ]
  }, {
    "id" : 44666,
    "reactomeId" : 11083924,
    "displayName" : "PDPK1:PIP3",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 678,
      "y" : 146
    },
    "minX" : 641,
    "maxX" : 721,
    "minY" : 129,
    "maxY" : 215,
    "prop" : {
      "x" : 641,
      "y" : 135,
      "width" : 74,
      "height" : 22
    },
    "textPosition" : {
      "x" : 652,
      "y" : 122
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 715,
          "y" : 135
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 715,
          "y" : 135
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 44662,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 677,
          "y" : 160
        },
        "to" : {
          "x" : 676,
          "y" : 207
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 676,
          "y" : 211
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 676,
          "y" : 211
        }
      }
    } ]
  } ],
  "edges" : [ {
    "id" : 44656,
    "reactomeId" : 11098785,
    "displayName" : "mTORC2 phosphorylates SGK1",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 390,
      "y" : 219
    },
    "minX" : 355,
    "maxX" : 421,
    "minY" : 213,
    "maxY" : 225,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 355,
        "y" : 221
      },
      "to" : {
        "x" : 390,
        "y" : 219
      }
    }, {
      "from" : {
        "x" : 390,
        "y" : 219
      },
      "to" : {
        "x" : 421,
        "y" : 220
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 384,
        "y" : 213
      },
      "b" : {
        "x" : 396,
        "y" : 225
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 390,
        "y" : 219
      }
    },
    "inputs" : [ {
      "id" : 44657,
      "points" : [ {
        "x" : 322,
        "y" : 219
      } ]
    }, {
      "id" : 44658,
      "points" : [ {
        "x" : 337,
        "y" : 244
      } ]
    } ],
    "outputs" : [ {
      "id" : 44659,
      "points" : [ {
        "x" : 466,
        "y" : 222
      } ]
    }, {
      "id" : 44660,
      "points" : [ {
        "x" : 433,
        "y" : 241
      } ]
    } ],
    "catalysts" : [ {
      "id" : 44661,
      "points" : [ {
        "x" : 389,
        "y" : 149
      } ]
    } ]
  }, {
    "id" : 44662,
    "reactomeId" : 11098795,
    "displayName" : "PDPK1 phosphorylates SGK1",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 676,
      "y" : 223
    },
    "minX" : 619,
    "maxX" : 719,
    "minY" : 217,
    "maxY" : 229,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 619,
        "y" : 221
      },
      "to" : {
        "x" : 676,
        "y" : 223
      }
    }, {
      "from" : {
        "x" : 676,
        "y" : 223
      },
      "to" : {
        "x" : 719,
        "y" : 226
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 670,
        "y" : 217
      },
      "b" : {
        "x" : 682,
        "y" : 229
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 676,
        "y" : 223
      }
    },
    "inputs" : [ {
      "id" : 44659,
      "points" : [ {
        "x" : 569,
        "y" : 223
      } ]
    }, {
      "id" : 44663,
      "points" : [ {
        "x" : 597,
        "y" : 246
      } ]
    } ],
    "outputs" : [ {
      "id" : 44664,
      "points" : [ {
        "x" : 747,
        "y" : 231
      } ]
    }, {
      "id" : 44665,
      "points" : [ {
        "x" : 730,
        "y" : 269
      } ]
    } ],
    "catalysts" : [ {
      "id" : 44666,
      "points" : [ {
        "x" : 677,
        "y" : 160
      } ]
    } ]
  } ],
  "compartments" : [ {
    "id" : 44667,
    "reactomeId" : 70101,
    "displayName" : "cytosol",
    "schemaClass" : "Compartment",
    "renderableClass" : "Compartment",
    "position" : {
      "x" : 968,
      "y" : 986
    },
    "minX" : 0,
    "maxX" : 1936,
    "minY" : 0,
    "maxY" : 1972,
    "prop" : {
      "x" : 0,
      "y" : 0,
      "width" : 1936,
      "height" : 1972
    },
    "textPosition" : {
      "x" : 29,
      "y" : 1874
    },
    "insets" : {
      "x" : 10,
      "y" : 10,
      "width" : 1916,
      "height" : 1952
    },
    "bgColor" : {
      "r" : 250,
      "g" : 240,
      "b" : 240
    },
    "componentIds" : [ 44678, 44679, 44697, 44678, 44679, 44697, 44678, 44679, 44697, 44678, 44679, 44697, 44678, 44679, 44697, 44678, 44679, 44697, 44679, 44697, 44678, 44679, 44697, 44678, 44678, 44679, 44656, 44657, 44658, 44659, 44664, 44662, 44660, 44663, 44665, 44684, 44668, 44666, 44712, 44661, 44713 ]
  }, {
    "id" : 44668,
    "reactomeId" : 7660,
    "displayName" : "nucleoplasm",
    "schemaClass" : "Compartment",
    "renderableClass" : "Compartment",
    "position" : {
      "x" : 900,
      "y" : 1112
    },
    "minX" : 39,
    "maxX" : 1761,
    "minY" : 379,
    "maxY" : 1846,
    "prop" : {
      "x" : 39,
      "y" : 379,
      "width" : 1722,
      "height" : 1467
    },
    "textPosition" : {
      "x" : 101,
      "y" : 1786
    },
    "insets" : {
      "x" : 49,
      "y" : 389,
      "width" : 1702,
      "height" : 1447
    },
    "bgColor" : {
      "r" : 250,
      "g" : 240,
      "b" : 240
    },
    "componentIds" : [ 44696, 44698, 44680, 44681, 44682, 44699, 44700, 44701, 44702, 44703, 44704, 44705, 44706, 44694, 44707, 44708, 44709, 44710, 44711 ]
  } ],
  "notes" : [ {
    "id" : 44684,
    "displayName" : "plasma membrane",
    "renderableClass" : "Note",
    "position" : {
      "x" : 166,
      "y" : 122
    },
    "minX" : 88,
    "maxX" : 245,
    "minY" : 109,
    "maxY" : 135,
    "prop" : {
      "x" : 88,
      "y" : 109,
      "width" : 157,
      "height" : 26
    },
    "textPosition" : {
      "x" : 104,
      "y" : 111
    }
  } ],
  "links" : [ {
    "id" : 44712,
    "renderableClass" : "Interaction",
    "position" : {
      "x" : 677,
      "y" : 112
    },
    "minX" : 671,
    "maxX" : 683,
    "minY" : 92,
    "maxY" : 132,
    "interactionType" : "Activate",
    "segments" : [ {
      "from" : {
        "x" : 677,
        "y" : 92
      },
      "to" : {
        "x" : 677,
        "y" : 132
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 673,
        "y" : 125
      },
      "b" : {
        "x" : 677,
        "y" : 132
      },
      "c" : {
        "x" : 681,
        "y" : 125
      },
      "type" : "ARROW",
      "empty" : true,
      "centre" : {
        "x" : 681,
        "y" : 125
      }
    },
    "reactionShape" : {
      "a" : {
        "x" : 671,
        "y" : 106
      },
      "b" : {
        "x" : 683,
        "y" : 118
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 677,
        "y" : 112
      }
    },
    "inputs" : [ {
      "id" : 44679
    } ],
    "outputs" : [ {
      "id" : 44666
    } ]
  }, {
    "id" : 44697,
    "renderableClass" : "Interaction",
    "position" : {
      "x" : 846,
      "y" : 136
    },
    "minX" : 738,
    "maxX" : 954,
    "minY" : 92,
    "maxY" : 180,
    "interactionType" : "Activate",
    "segments" : [ {
      "from" : {
        "x" : 738,
        "y" : 92
      },
      "to" : {
        "x" : 954,
        "y" : 180
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 946,
        "y" : 181
      },
      "b" : {
        "x" : 954,
        "y" : 180
      },
      "c" : {
        "x" : 949,
        "y" : 174
      },
      "type" : "ARROW",
      "empty" : true,
      "centre" : {
        "x" : 949,
        "y" : 174
      }
    },
    "reactionShape" : {
      "a" : {
        "x" : 840,
        "y" : 130
      },
      "b" : {
        "x" : 852,
        "y" : 142
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 846,
        "y" : 136
      }
    },
    "inputs" : [ {
      "id" : 44679
    } ],
    "outputs" : [ {
      "id" : 44678
    } ]
  }, {
    "id" : 44713,
    "renderableClass" : "Interaction",
    "position" : {
      "x" : 518,
      "y" : 102
    },
    "minX" : 435,
    "maxX" : 601,
    "minY" : 81,
    "maxY" : 123,
    "interactionType" : "Activate",
    "segments" : [ {
      "from" : {
        "x" : 601,
        "y" : 81
      },
      "to" : {
        "x" : 435,
        "y" : 123
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 441,
        "y" : 117
      },
      "b" : {
        "x" : 435,
        "y" : 123
      },
      "c" : {
        "x" : 443,
        "y" : 125
      },
      "type" : "ARROW",
      "empty" : true,
      "centre" : {
        "x" : 443,
        "y" : 125
      }
    },
    "reactionShape" : {
      "a" : {
        "x" : 512,
        "y" : 96
      },
      "b" : {
        "x" : 524,
        "y" : 108
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 518,
        "y" : 102
      }
    },
    "inputs" : [ {
      "id" : 44679
    } ],
    "outputs" : [ {
      "id" : 44661
    } ]
  }, {
    "id" : 44699,
    "renderableClass" : "Interaction",
    "position" : {
      "x" : 1444,
      "y" : 792
    },
    "minX" : 1438,
    "maxX" : 1450,
    "minY" : 702,
    "maxY" : 883,
    "interactionType" : "Activate",
    "segments" : [ {
      "from" : {
        "x" : 1445,
        "y" : 702
      },
      "to" : {
        "x" : 1443,
        "y" : 883
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 1439,
        "y" : 876
      },
      "b" : {
        "x" : 1443,
        "y" : 883
      },
      "c" : {
        "x" : 1447,
        "y" : 876
      },
      "type" : "ARROW",
      "empty" : true,
      "centre" : {
        "x" : 1447,
        "y" : 876
      }
    },
    "reactionShape" : {
      "a" : {
        "x" : 1438,
        "y" : 786
      },
      "b" : {
        "x" : 1450,
        "y" : 798
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 1444,
        "y" : 792
      }
    },
    "inputs" : [ {
      "id" : 44680
    } ],
    "outputs" : [ {
      "id" : 44682
    } ]
  }, {
    "id" : 44700,
    "renderableClass" : "Interaction",
    "position" : {
      "x" : 1435,
      "y" : 1035
    },
    "minX" : 1429,
    "maxX" : 1441,
    "minY" : 966,
    "maxY" : 1104,
    "interactionType" : "Activate",
    "segments" : [ {
      "from" : {
        "x" : 1440,
        "y" : 966
      },
      "to" : {
        "x" : 1431,
        "y" : 1104
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 1427,
        "y" : 1097
      },
      "b" : {
        "x" : 1431,
        "y" : 1104
      },
      "c" : {
        "x" : 1435,
        "y" : 1097
      },
      "type" : "ARROW",
      "empty" : true,
      "centre" : {
        "x" : 1435,
        "y" : 1097
      }
    },
    "reactionShape" : {
      "a" : {
        "x" : 1429,
        "y" : 1029
      },
      "b" : {
        "x" : 1441,
        "y" : 1041
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 1435,
        "y" : 1035
      }
    },
    "inputs" : [ {
      "id" : 44682
    } ],
    "outputs" : [ {
      "id" : 44681
    } ]
  } ],
  "shadows" : [ {
    "id" : 44714,
    "reactomeId" : 11107998,
    "displayName" : "Regulation of TP53 Degradation",
    "schemaClass" : "Pathway",
    "renderableClass" : "Shadow",
    "position" : {
      "x" : 582,
      "y" : 209
    },
    "minX" : 269,
    "maxX" : 896,
    "minY" : 113,
    "maxY" : 305,
    "prop" : {
      "x" : 269,
      "y" : 113,
      "width" : 627,
      "height" : 192
    },
    "points" : [ {
      "x" : 269,
      "y" : 113
    }, {
      "x" : 896,
      "y" : 113
    }, {
      "x" : 896,
      "y" : 305
    }, {
      "x" : 269,
      "y" : 305
    } ],
    "colour" : "#4684ee"
  } ],
  "minX" : 0,
  "maxX" : 1936,
  "minY" : 0,
  "maxY" : 1972,
  "disease" : false
}