{ "dbId" : 11106928, "stableId" : "R-SCE-425397", "displayName" : "Transport of vitamins, nucleosides, and related molecules", "nodes" : [ { "id" : 69313, "reactomeId" : 742361, "displayName" : "UDP-Xyl", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 589, "y" : 696 }, "minX" : 557, "maxX" : 622, "minY" : 680, "maxY" : 711, "prop" : { "x" : 557, "y" : 681, "width" : 64, "height" : 30 }, "textPosition" : { "x" : 562, "y" : 685 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 616, "y" : 686 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 616, "y" : 686 } } }, "connectors" : [ { "edgeId" : 69311, "type" : "OUTPUT", "segments" : [ ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 69312, "reactomeId" : 742353, "displayName" : "UDP-Xyl", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 427, "y" : 693 }, "minX" : 395, "maxX" : 461, "minY" : 677, "maxY" : 708, "prop" : { "x" : 395, "y" : 678, "width" : 65, "height" : 30 }, "textPosition" : { "x" : 400, "y" : 682 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 455, "y" : 683 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 455, "y" : 683 } } }, "connectors" : [ { "edgeId" : 69311, "type" : "INPUT", "segments" : [ ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 69314, "reactomeId" : 11090033, "displayName" : "YEA4", "schemaClass" : "EntityWithAccessionedSequence", "renderableClass" : "Protein", "position" : { "x" : 501, "y" : 729 }, "minX" : 471, "maxX" : 537, "minY" : 703, "maxY" : 740, "prop" : { "x" : 471, "y" : 718, "width" : 60, "height" : 22 }, "textPosition" : { "x" : 481, "y" : 718 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 531, "y" : 718 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 531, "y" : 718 } } }, "connectors" : [ { "edgeId" : 69311, "type" : "CATALYST", "segments" : [ { "from" : { "x" : 501, "y" : 715 }, "to" : { "x" : 501, "y" : 711 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "c" : { "x" : 502, "y" : 707 }, "r" : 4, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 502, "y" : 707 } } } ] }, { "id" : 69317, "reactomeId" : 113593, "displayName" : "ATP", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 741, "y" : 1166 }, "minX" : 721, "maxX" : 771, "minY" : 1114, "maxY" : 1181, "prop" : { "x" : 721, "y" : 1151, "width" : 40, "height" : 30 }, "textPosition" : { "x" : 725, "y" : 1155 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 756, "y" : 1156 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 756, "y" : 1156 } } }, "connectors" : [ { "edgeId" : 69315, "type" : "INPUT", "segments" : [ { "from" : { "x" : 749, "y" : 1148 }, "to" : { "x" : 771, "y" : 1114 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 69316, "reactomeId" : 29370, "displayName" : "ADP", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 854, "y" : 1118 }, "minX" : 771, "maxX" : 876, "minY" : 1102, "maxY" : 1133, "prop" : { "x" : 834, "y" : 1103, "width" : 41, "height" : 30 }, "textPosition" : { "x" : 838, "y" : 1107 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 870, "y" : 1108 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 870, "y" : 1108 } } }, "connectors" : [ { "edgeId" : 69315, "type" : "INPUT", "segments" : [ { "from" : { "x" : 831, "y" : 1117 }, "to" : { "x" : 771, "y" : 1114 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 69319, "reactomeId" : 113592, "displayName" : "ATP", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 399, "y" : 1041 }, "minX" : 379, "maxX" : 616, "minY" : 1025, "maxY" : 1115, "prop" : { "x" : 379, "y" : 1026, "width" : 40, "height" : 30 }, "textPosition" : { "x" : 383, "y" : 1030 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 414, "y" : 1031 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 414, "y" : 1031 } } }, "connectors" : [ { "edgeId" : 69315, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 422, "y" : 1047 }, "to" : { "x" : 616, "y" : 1115 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 430, "y" : 1046 }, "b" : { "x" : 422, "y" : 1047 }, "c" : { "x" : 427, "y" : 1053 }, "type" : "ARROW", "centre" : { "x" : 427, "y" : 1053 } } } ] }, { "id" : 69318, "reactomeId" : 113581, "displayName" : "ADP", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 586, "y" : 1152 }, "minX" : 566, "maxX" : 616, "minY" : 1115, "maxY" : 1167, "prop" : { "x" : 566, "y" : 1137, "width" : 41, "height" : 30 }, "textPosition" : { "x" : 570, "y" : 1141 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 602, "y" : 1142 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 602, "y" : 1142 } } }, "connectors" : [ { "edgeId" : 69315, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 598, "y" : 1134 }, "to" : { "x" : 616, "y" : 1115 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 600, "y" : 1126 }, "b" : { "x" : 598, "y" : 1134 }, "c" : { "x" : 606, "y" : 1132 }, "type" : "ARROW", "centre" : { "x" : 606, "y" : 1132 } } } ] }, { "id" : 69289, "reactomeId" : 179743, "displayName" : "ligands of SLC28A3 & 29A1", "schemaClass" : "DefinedSet", "renderableClass" : "EntitySet", "position" : { "x" : 317, "y" : 198 }, "minX" : 256, "maxX" : 379, "minY" : 183, "maxY" : 214, "prop" : { "x" : 256, "y" : 183, "width" : 123, "height" : 31 }, "textPosition" : { "x" : 261, "y" : 181 }, "connectors" : [ { "edgeId" : 69296, "type" : "OUTPUT", "segments" : [ ], "stoichiometry" : { "value" : 1 } }, { "edgeId" : 69288, "type" : "INPUT", "segments" : [ ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 69320, "reactomeId" : 11084877, "displayName" : "SLC25A5,6 dimers", "schemaClass" : "DefinedSet", "renderableClass" : "EntitySet", "position" : { "x" : 657, "y" : 1189 }, "minX" : 599, "maxX" : 716, "minY" : 1122, "maxY" : 1200, "prop" : { "x" : 599, "y" : 1178, "width" : 117, "height" : 22 }, "textPosition" : { "x" : 618, "y" : 1172 }, "connectors" : [ { "edgeId" : 69315, "type" : "CATALYST", "segments" : [ { "from" : { "x" : 656, "y" : 1172 }, "to" : { "x" : 656, "y" : 1130 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "c" : { "x" : 656, "y" : 1126 }, "r" : 4, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 656, "y" : 1126 } } } ] }, { "id" : 69291, "reactomeId" : 11083889, "displayName" : "FUN26", "schemaClass" : "EntityWithAccessionedSequence", "renderableClass" : "Protein", "position" : { "x" : 467, "y" : 102 }, "minX" : 386, "maxX" : 519, "minY" : 78, "maxY" : 120, "prop" : { "x" : 421, "y" : 84, "width" : 92, "height" : 36 }, "textPosition" : { "x" : 442, "y" : 91 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 513, "y" : 84 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 513, "y" : 84 } } }, "connectors" : [ { "edgeId" : 69296, "type" : "CATALYST", "segments" : [ { "from" : { "x" : 415, "y" : 107 }, "to" : { "x" : 396, "y" : 110 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "c" : { "x" : 392, "y" : 111 }, "r" : 4, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 392, "y" : 111 } } }, { "edgeId" : 69288, "type" : "CATALYST", "segments" : [ { "from" : { "x" : 415, "y" : 97 }, "to" : { "x" : 394, "y" : 95 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "c" : { "x" : 390, "y" : 94 }, "r" : 4, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 390, "y" : 94 } } } ] }, { "id" : 69290, "reactomeId" : 179737, "displayName" : "ligands of SLC28A3 & 29A1", "schemaClass" : "DefinedSet", "renderableClass" : "EntitySet", "position" : { "x" : 298, "y" : 15 }, "minX" : 234, "maxX" : 362, "minY" : 0, "maxY" : 31, "prop" : { "x" : 234, "y" : 0, "width" : 128, "height" : 31 }, "textPosition" : { "x" : 233, "y" : -2 }, "connectors" : [ { "edgeId" : 69296, "type" : "INPUT", "segments" : [ ], "stoichiometry" : { "value" : 1 } }, { "edgeId" : 69288, "type" : "OUTPUT", "segments" : [ ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 69293, "reactomeId" : 179742, "displayName" : "ligands of SLC29A2", "schemaClass" : "DefinedSet", "renderableClass" : "EntitySet", "position" : { "x" : 877, "y" : 172 }, "minX" : 817, "maxX" : 938, "minY" : 161, "maxY" : 183, "prop" : { "x" : 817, "y" : 161, "width" : 121, "height" : 22 }, "textPosition" : { "x" : 841, "y" : 155 }, "connectors" : [ { "edgeId" : 69297, "type" : "OUTPUT", "segments" : [ ], "stoichiometry" : { "value" : 1 } }, { "edgeId" : 69292, "type" : "INPUT", "segments" : [ ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 69295, "reactomeId" : 11083887, "displayName" : "FUN26", "schemaClass" : "EntityWithAccessionedSequence", "renderableClass" : "Protein", "position" : { "x" : 792, "y" : 104 }, "minX" : 746, "maxX" : 889, "minY" : 80, "maxY" : 122, "prop" : { "x" : 746, "y" : 86, "width" : 92, "height" : 36 }, "textPosition" : { "x" : 767, "y" : 93 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 838, "y" : 86 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 838, "y" : 86 } } }, "connectors" : [ { "edgeId" : 69297, "type" : "CATALYST", "segments" : [ { "from" : { "x" : 844, "y" : 107 }, "to" : { "x" : 881, "y" : 110 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "c" : { "x" : 885, "y" : 111 }, "r" : 4, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 885, "y" : 111 } } }, { "edgeId" : 69292, "type" : "CATALYST", "segments" : [ { "from" : { "x" : 844, "y" : 100 }, "to" : { "x" : 859, "y" : 99 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "c" : { "x" : 863, "y" : 99 }, "r" : 4, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 863, "y" : 99 } } } ] }, { "id" : 69294, "reactomeId" : 179747, "displayName" : "ligands of SLC29A2", "schemaClass" : "DefinedSet", "renderableClass" : "EntitySet", "position" : { "x" : 863, "y" : 41 }, "minX" : 803, "maxX" : 924, "minY" : 30, "maxY" : 52, "prop" : { "x" : 803, "y" : 30, "width" : 121, "height" : 22 }, "textPosition" : { "x" : 827, "y" : 24 }, "connectors" : [ { "edgeId" : 69297, "type" : "INPUT", "segments" : [ ], "stoichiometry" : { "value" : 1 } }, { "edgeId" : 69292, "type" : "OUTPUT", "segments" : [ ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 69299, "reactomeId" : 727782, "displayName" : "nucleosides", "schemaClass" : "DefinedSet", "renderableClass" : "EntitySet", "position" : { "x" : 336, "y" : 339 }, "minX" : 276, "maxX" : 397, "minY" : 328, "maxY" : 350, "prop" : { "x" : 276, "y" : 328, "width" : 121, "height" : 22 }, "textPosition" : { "x" : 295, "y" : 328 }, "connectors" : [ { "edgeId" : 69298, "type" : "INPUT", "segments" : [ ], "stoichiometry" : { "value" : 1 } }, { "edgeId" : 69302, "type" : "OUTPUT", "segments" : [ ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 69301, "reactomeId" : 11090015, "displayName" : "FUN26", "schemaClass" : "EntityWithAccessionedSequence", "renderableClass" : "Protein", "position" : { "x" : 230, "y" : 389 }, "minX" : 200, "maxX" : 267, "minY" : 335, "maxY" : 400, "prop" : { "x" : 200, "y" : 378, "width" : 61, "height" : 22 }, "textPosition" : { "x" : 206, "y" : 378 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 261, "y" : 378 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 261, "y" : 378 } } }, "connectors" : [ { "edgeId" : 69298, "type" : "CATALYST", "segments" : [ { "from" : { "x" : 229, "y" : 375 }, "to" : { "x" : 227, "y" : 343 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "c" : { "x" : 227, "y" : 339 }, "r" : 4, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 227, "y" : 339 } } }, { "edgeId" : 69302, "type" : "CATALYST", "segments" : [ { "from" : { "x" : 232, "y" : 375 }, "to" : { "x" : 235, "y" : 362 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "c" : { "x" : 236, "y" : 358 }, "r" : 4, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 236, "y" : 358 } } } ] }, { "id" : 69300, "reactomeId" : 727746, "displayName" : "nucleosides", "schemaClass" : "DefinedSet", "renderableClass" : "EntitySet", "position" : { "x" : 118, "y" : 339 }, "minX" : 58, "maxX" : 179, "minY" : 328, "maxY" : 350, "prop" : { "x" : 58, "y" : 328, "width" : 121, "height" : 22 }, "textPosition" : { "x" : 77, "y" : 328 }, "connectors" : [ { "edgeId" : 69298, "type" : "OUTPUT", "segments" : [ ], "stoichiometry" : { "value" : 1 } }, { "edgeId" : 69302, "type" : "INPUT", "segments" : [ ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 69305, "reactomeId" : 727753, "displayName" : "Ac-CoA", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 634, "y" : 471 }, "minX" : 604, "maxX" : 666, "minY" : 455, "maxY" : 486, "prop" : { "x" : 604, "y" : 456, "width" : 61, "height" : 30 }, "textPosition" : { "x" : 609, "y" : 460 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 660, "y" : 461 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 660, "y" : 461 } } }, "connectors" : [ { "edgeId" : 69303, "type" : "OUTPUT", "segments" : [ ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 69304, "reactomeId" : 76183, "displayName" : "Ac-CoA", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 633, "y" : 339 }, "minX" : 603, "maxX" : 665, "minY" : 323, "maxY" : 354, "prop" : { "x" : 603, "y" : 324, "width" : 61, "height" : 30 }, "textPosition" : { "x" : 608, "y" : 328 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 659, "y" : 329 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 659, "y" : 329 } } }, "connectors" : [ { "edgeId" : 69303, "type" : "INPUT", "segments" : [ ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 69306, "reactomeId" : 11090023, "displayName" : "SLC33A1", "schemaClass" : "EntityWithAccessionedSequence", "renderableClass" : "Protein", "position" : { "x" : 544, "y" : 413 }, "minX" : 514, "maxX" : 625, "minY" : 396, "maxY" : 424, "prop" : { "x" : 514, "y" : 402, "width" : 61, "height" : 22 }, "textPosition" : { "x" : 517, "y" : 396 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 575, "y" : 402 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 575, "y" : 402 } } }, "connectors" : [ { "edgeId" : 69303, "type" : "CATALYST", "segments" : [ { "from" : { "x" : 578, "y" : 412 }, "to" : { "x" : 617, "y" : 411 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "c" : { "x" : 621, "y" : 411 }, "r" : 4, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 621, "y" : 411 } } } ] }, { "id" : 69309, "reactomeId" : 914003, "displayName" : "UDP-GlcNAc", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 644, "y" : 620 }, "minX" : 600, "maxX" : 690, "minY" : 604, "maxY" : 635, "prop" : { "x" : 600, "y" : 605, "width" : 89, "height" : 30 }, "textPosition" : { "x" : 604, "y" : 609 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 684, "y" : 610 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 684, "y" : 610 } } }, "connectors" : [ { "edgeId" : 69307, "type" : "OUTPUT", "segments" : [ ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 69308, "reactomeId" : 162756, "displayName" : "UDP-GlcNAc", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 421, "y" : 648 }, "minX" : 377, "maxX" : 467, "minY" : 632, "maxY" : 663, "prop" : { "x" : 377, "y" : 633, "width" : 89, "height" : 30 }, "textPosition" : { "x" : 381, "y" : 637 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 461, "y" : 638 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 461, "y" : 638 } } }, "connectors" : [ { "edgeId" : 69307, "type" : "INPUT", "segments" : [ ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 69310, "reactomeId" : 11090033, "displayName" : "YEA4", "schemaClass" : "EntityWithAccessionedSequence", "renderableClass" : "Protein", "position" : { "x" : 499, "y" : 624 }, "minX" : 469, "maxX" : 535, "minY" : 607, "maxY" : 650, "prop" : { "x" : 469, "y" : 613, "width" : 60, "height" : 22 }, "textPosition" : { "x" : 479, "y" : 613 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 529, "y" : 613 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 529, "y" : 613 } } }, "connectors" : [ { "edgeId" : 69307, "type" : "CATALYST", "segments" : [ { "from" : { "x" : 500, "y" : 638 }, "to" : { "x" : 501, "y" : 642 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "c" : { "x" : 502, "y" : 646 }, "r" : 4, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 502, "y" : 646 } } } ] } ], "edges" : [ { "id" : 69297, "reactomeId" : 11083892, "displayName" : "Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2", "schemaClass" : "Reaction", "renderableClass" : "Reaction", "position" : { "x" : 897, "y" : 112 }, "minX" : 868, "maxX" : 903, "minY" : 58, "maxY" : 155, "reactionType" : "transition", "segments" : [ { "from" : { "x" : 868, "y" : 58 }, "to" : { "x" : 897, "y" : 112 } }, { "from" : { "x" : 897, "y" : 112 }, "to" : { "x" : 880, "y" : 155 } } ], "endShape" : { "a" : { "x" : 879, "y" : 147 }, "b" : { "x" : 880, "y" : 155 }, "c" : { "x" : 886, "y" : 150 }, "type" : "ARROW", "centre" : { "x" : 886, "y" : 150 } }, "reactionShape" : { "a" : { "x" : 891, "y" : 106 }, "b" : { "x" : 903, "y" : 118 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 897, "y" : 112 } }, "inputs" : [ { "id" : 69294 } ], "outputs" : [ { "id" : 69293 } ], "catalysts" : [ { "id" : 69295, "points" : [ { "x" : 844, "y" : 107 } ] } ] }, { "id" : 69296, "reactomeId" : 11083899, "displayName" : "Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1", "schemaClass" : "Reaction", "renderableClass" : "Reaction", "position" : { "x" : 380, "y" : 113 }, "minX" : 310, "maxX" : 386, "minY" : 37, "maxY" : 177, "reactionType" : "transition", "segments" : [ { "from" : { "x" : 310, "y" : 37 }, "to" : { "x" : 380, "y" : 113 } }, { "from" : { "x" : 380, "y" : 113 }, "to" : { "x" : 328, "y" : 177 } } ], "endShape" : { "a" : { "x" : 329, "y" : 169 }, "b" : { "x" : 328, "y" : 177 }, "c" : { "x" : 335, "y" : 174 }, "type" : "ARROW", "centre" : { "x" : 335, "y" : 174 } }, "reactionShape" : { "a" : { "x" : 374, "y" : 107 }, "b" : { "x" : 386, "y" : 119 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 380, "y" : 113 } }, "inputs" : [ { "id" : 69290 } ], "outputs" : [ { "id" : 69289 } ], "catalysts" : [ { "id" : 69291, "points" : [ { "x" : 415, "y" : 107 } ] } ] }, { "id" : 69315, "reactomeId" : 11084880, "displayName" : "SLC25A5,6 dimers exchange ATP for ADP across the mitochondrial inner membrane", "schemaClass" : "Reaction", "renderableClass" : "Reaction", "position" : { "x" : 656, "y" : 1114 }, "minX" : 616, "maxX" : 771, "minY" : 1108, "maxY" : 1120, "reactionType" : "transition", "segments" : [ { "from" : { "x" : 771, "y" : 1114 }, "to" : { "x" : 656, "y" : 1114 } }, { "from" : { "x" : 656, "y" : 1114 }, "to" : { "x" : 616, "y" : 1115 } } ], "reactionShape" : { "a" : { "x" : 650, "y" : 1108 }, "b" : { "x" : 662, "y" : 1120 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 656, "y" : 1114 } }, "inputs" : [ { "id" : 69316, "points" : [ { "x" : 831, "y" : 1117 } ] }, { "id" : 69317, "points" : [ { "x" : 749, "y" : 1148 } ] } ], "outputs" : [ { "id" : 69318, "points" : [ { "x" : 598, "y" : 1134 } ] }, { "id" : 69319, "points" : [ { "x" : 422, "y" : 1047 } ] } ], "catalysts" : [ { "id" : 69320, "points" : [ { "x" : 656, "y" : 1172 } ] } ] }, { "id" : 69298, "reactomeId" : 11090018, "displayName" : "SLC29A3 transports nucleosides from lysosomal lumen to cytosol", "schemaClass" : "Reaction", "renderableClass" : "Reaction", "position" : { "x" : 226, "y" : 327 }, "minX" : 185, "maxX" : 270, "minY" : 321, "maxY" : 333, "reactionType" : "transition", "segments" : [ { "from" : { "x" : 270, "y" : 332 }, "to" : { "x" : 226, "y" : 327 } }, { "from" : { "x" : 226, "y" : 327 }, "to" : { "x" : 185, "y" : 332 } } ], "endShape" : { "a" : { "x" : 191, "y" : 327 }, "b" : { "x" : 185, "y" : 332 }, "c" : { "x" : 192, "y" : 335 }, "type" : "ARROW", "centre" : { "x" : 192, "y" : 335 } }, "reactionShape" : { "a" : { "x" : 220, "y" : 321 }, "b" : { "x" : 232, "y" : 333 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 226, "y" : 327 } }, "inputs" : [ { "id" : 69299 } ], "outputs" : [ { "id" : 69300 } ], "catalysts" : [ { "id" : 69301, "points" : [ { "x" : 229, "y" : 375 } ] } ] }, { "id" : 69303, "reactomeId" : 11090026, "displayName" : "SLC33A1 transports Ac-CoA from cytosol to Golgi lumen", "schemaClass" : "Reaction", "renderableClass" : "Reaction", "position" : { "x" : 633, "y" : 411 }, "minX" : 627, "maxX" : 639, "minY" : 357, "maxY" : 453, "reactionType" : "transition", "segments" : [ { "from" : { "x" : 633, "y" : 357 }, "to" : { "x" : 633, "y" : 411 } }, { "from" : { "x" : 633, "y" : 411 }, "to" : { "x" : 633, "y" : 453 } } ], "endShape" : { "a" : { "x" : 629, "y" : 446 }, "b" : { "x" : 633, "y" : 453 }, "c" : { "x" : 637, "y" : 446 }, "type" : "ARROW", "centre" : { "x" : 637, "y" : 446 } }, "reactionShape" : { "a" : { "x" : 627, "y" : 405 }, "b" : { "x" : 639, "y" : 417 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 633, "y" : 411 } }, "inputs" : [ { "id" : 69304 } ], "outputs" : [ { "id" : 69305 } ], "catalysts" : [ { "id" : 69306, "points" : [ { "x" : 578, "y" : 412 } ] } ] }, { "id" : 69302, "reactomeId" : 11090028, "displayName" : "SLC29A3 transports nucleosides from cytosol to lysosomal lumen", "schemaClass" : "Reaction", "renderableClass" : "Reaction", "position" : { "x" : 239, "y" : 346 }, "minX" : 185, "maxX" : 270, "minY" : 340, "maxY" : 352, "reactionType" : "transition", "segments" : [ { "from" : { "x" : 185, "y" : 342 }, "to" : { "x" : 239, "y" : 346 } }, { "from" : { "x" : 239, "y" : 346 }, "to" : { "x" : 270, "y" : 343 } } ], "endShape" : { "a" : { "x" : 263, "y" : 348 }, "b" : { "x" : 270, "y" : 343 }, "c" : { "x" : 263, "y" : 340 }, "type" : "ARROW", "centre" : { "x" : 263, "y" : 340 } }, "reactionShape" : { "a" : { "x" : 233, "y" : 340 }, "b" : { "x" : 245, "y" : 352 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 239, "y" : 346 } }, "inputs" : [ { "id" : 69300 } ], "outputs" : [ { "id" : 69299 } ], "catalysts" : [ { "id" : 69301, "points" : [ { "x" : 232, "y" : 375 } ] } ] }, { "id" : 69288, "reactomeId" : 11083897, "displayName" : "Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1", "schemaClass" : "Reaction", "renderableClass" : "Reaction", "position" : { "x" : 378, "y" : 93 }, "minX" : 313, "maxX" : 384, "minY" : 37, "maxY" : 177, "reactionType" : "transition", "segments" : [ { "from" : { "x" : 326, "y" : 177 }, "to" : { "x" : 378, "y" : 93 } }, { "from" : { "x" : 378, "y" : 93 }, "to" : { "x" : 313, "y" : 37 } } ], "endShape" : { "a" : { "x" : 321, "y" : 38 }, "b" : { "x" : 313, "y" : 37 }, "c" : { "x" : 316, "y" : 45 }, "type" : "ARROW", "centre" : { "x" : 316, "y" : 45 } }, "reactionShape" : { "a" : { "x" : 372, "y" : 87 }, "b" : { "x" : 384, "y" : 99 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 378, "y" : 93 } }, "inputs" : [ { "id" : 69289 } ], "outputs" : [ { "id" : 69290 } ], "catalysts" : [ { "id" : 69291, "points" : [ { "x" : 415, "y" : 97 } ] } ] }, { "id" : 69307, "reactomeId" : 11090036, "displayName" : "SLC35B4 mediates the transport of UDP-N-acetylglucosamine into the Golgi lumen", "schemaClass" : "Reaction", "renderableClass" : "Reaction", "position" : { "x" : 504, "y" : 658 }, "minX" : 469, "maxX" : 597, "minY" : 632, "maxY" : 664, "reactionType" : "transition", "segments" : [ { "from" : { "x" : 469, "y" : 653 }, "to" : { "x" : 504, "y" : 658 } }, { "from" : { "x" : 504, "y" : 658 }, "to" : { "x" : 597, "y" : 632 } } ], "endShape" : { "a" : { "x" : 591, "y" : 638 }, "b" : { "x" : 597, "y" : 632 }, "c" : { "x" : 589, "y" : 630 }, "type" : "ARROW", "centre" : { "x" : 589, "y" : 630 } }, "reactionShape" : { "a" : { "x" : 498, "y" : 652 }, "b" : { "x" : 510, "y" : 664 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 504, "y" : 658 } }, "inputs" : [ { "id" : 69308 } ], "outputs" : [ { "id" : 69309 } ], "catalysts" : [ { "id" : 69310, "points" : [ { "x" : 500, "y" : 638 } ] } ] }, { "id" : 69292, "reactomeId" : 11083894, "displayName" : "Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2", "schemaClass" : "Reaction", "renderableClass" : "Reaction", "position" : { "x" : 875, "y" : 98 }, "minX" : 865, "maxX" : 881, "minY" : 58, "maxY" : 155, "reactionType" : "transition", "segments" : [ { "from" : { "x" : 876, "y" : 155 }, "to" : { "x" : 875, "y" : 98 } }, { "from" : { "x" : 875, "y" : 98 }, "to" : { "x" : 865, "y" : 58 } } ], "endShape" : { "a" : { "x" : 871, "y" : 64 }, "b" : { "x" : 865, "y" : 58 }, "c" : { "x" : 863, "y" : 66 }, "type" : "ARROW", "centre" : { "x" : 863, "y" : 66 } }, "reactionShape" : { "a" : { "x" : 869, "y" : 92 }, "b" : { "x" : 881, "y" : 104 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 875, "y" : 98 } }, "inputs" : [ { "id" : 69293 } ], "outputs" : [ { "id" : 69294 } ], "catalysts" : [ { "id" : 69295, "points" : [ { "x" : 844, "y" : 100 } ] } ] }, { "id" : 69311, "reactomeId" : 11090039, "displayName" : "SLC35B4 mediates the transport of UDP-xylose into the Golgi lumen", "schemaClass" : "Reaction", "renderableClass" : "Reaction", "position" : { "x" : 503, "y" : 695 }, "minX" : 463, "maxX" : 554, "minY" : 689, "maxY" : 701, "reactionType" : "transition", "segments" : [ { "from" : { "x" : 463, "y" : 693 }, "to" : { "x" : 503, "y" : 695 } }, { "from" : { "x" : 503, "y" : 695 }, "to" : { "x" : 554, "y" : 695 } } ], "endShape" : { "a" : { "x" : 547, "y" : 699 }, "b" : { "x" : 554, "y" : 695 }, "c" : { "x" : 547, "y" : 691 }, "type" : "ARROW", "centre" : { "x" : 547, "y" : 691 } }, "reactionShape" : { "a" : { "x" : 497, "y" : 689 }, "b" : { "x" : 509, "y" : 701 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 503, "y" : 695 } }, "inputs" : [ { "id" : 69312 } ], "outputs" : [ { "id" : 69313 } ], "catalysts" : [ { "id" : 69314, "points" : [ { "x" : 501, "y" : 715 } ] } ] } ], "compartments" : [ { "id" : 69329, "reactomeId" : 17963, "displayName" : "Golgi lumen", "schemaClass" : "Compartment", "renderableClass" : "Compartment", "position" : { "x" : 803, "y" : 733 }, "minX" : 496, "maxX" : 1110, "minY" : 406, "maxY" : 1061, "prop" : { "x" : 496, "y" : 406, "width" : 614, "height" : 655 }, "textPosition" : { "x" : 680, "y" : 457 }, "insets" : { "x" : 506, "y" : 416, "width" : 594, "height" : 635 }, "bgColor" : { "r" : 250, "g" : 240, "b" : 240 }, "componentIds" : [ 69306, 69303, 69305, 69307, 69314, 69311, 69313, 69310, 69309 ] }, { "id" : 69328, "reactomeId" : 161320, "displayName" : "lysosomal lumen", "schemaClass" : "Compartment", "renderableClass" : "Compartment", "position" : { "x" : 323, "y" : 349 }, "minX" : 225, "maxX" : 422, "minY" : 258, "maxY" : 440, "prop" : { "x" : 225, "y" : 258, "width" : 197, "height" : 182 }, "textPosition" : { "x" : 270, "y" : 270 }, "insets" : { "x" : 235, "y" : 268, "width" : 177, "height" : 162 }, "bgColor" : { "r" : 250, "g" : 240, "b" : 240 }, "componentIds" : [ 69302, 69301, 69298, 69299 ] }, { "id" : 69349, "reactomeId" : 17957, "displayName" : "endoplasmic reticulum lumen", "schemaClass" : "Compartment", "renderableClass" : "Compartment", "position" : { "x" : 174, "y" : 890 }, "minX" : 43, "maxX" : 305, "minY" : 815, "maxY" : 965, "prop" : { "x" : 43, "y" : 815, "width" : 262, "height" : 150 }, "textPosition" : { "x" : 65, "y" : 901 }, "insets" : { "x" : 53, "y" : 825, "width" : 242, "height" : 130 }, "bgColor" : { "r" : 250, "g" : 240, "b" : 240 } }, { "id" : 69321, "reactomeId" : 70101, "displayName" : "cytosol", "schemaClass" : "Compartment", "renderableClass" : "Compartment", "position" : { "x" : 696, "y" : 662 }, "minX" : 0, "maxX" : 1392, "minY" : 99, "maxY" : 1226, "prop" : { "x" : 0, "y" : 99, "width" : 1392, "height" : 1127 }, "textPosition" : { "x" : 493, "y" : 195 }, "insets" : { "x" : 10, "y" : 109, "width" : 1372, "height" : 1107 }, "bgColor" : { "r" : 250, "g" : 240, "b" : 240 }, "componentIds" : [ 69289, 69293, 69296, 69297, 69328, 69300, 69329, 69304, 69312, 69349, 69308, 69295, 69291, 69356, 69319, 69316 ] }, { "id" : 69355, "reactomeId" : 5460, "displayName" : "mitochondrial matrix", "schemaClass" : "Compartment", "renderableClass" : "Compartment", "position" : { "x" : 523, "y" : 1156 }, "minX" : 268, "maxX" : 779, "minY" : 1111, "maxY" : 1202, "prop" : { "x" : 268, "y" : 1111, "width" : 511, "height" : 91 }, "textPosition" : { "x" : 630, "y" : 1120 }, "insets" : { "x" : 278, "y" : 1121, "width" : 491, "height" : 71 }, "bgColor" : { "r" : 250, "g" : 240, "b" : 240 }, "componentIds" : [ 69318, 69320, 69315, 69317 ] }, { "id" : 69356, "reactomeId" : 17927, "displayName" : "mitochondrial intermembrane space", "schemaClass" : "Compartment", "renderableClass" : "Compartment", "position" : { "x" : 529, "y" : 1143 }, "minX" : 252, "maxX" : 807, "minY" : 1074, "maxY" : 1213, "prop" : { "x" : 252, "y" : 1074, "width" : 555, "height" : 139 }, "textPosition" : { "x" : 567, "y" : 1084 }, "insets" : { "x" : 262, "y" : 1084, "width" : 535, "height" : 119 }, "bgColor" : { "r" : 250, "g" : 240, "b" : 240 }, "componentIds" : [ 69355 ] } ], "notes" : [ ], "links" : [ ], "shadows" : [ { "id" : 69357, "reactomeId" : 11106926, "displayName" : "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane", "schemaClass" : "Pathway", "renderableClass" : "Shadow", "position" : { "x" : 498, "y" : 600 }, "minX" : 48, "maxX" : 948, "minY" : -10, "maxY" : 1210, "prop" : { "x" : 48, "y" : 750, "width" : 900, "height" : 460 }, "points" : [ { "x" : 48, "y" : -10 }, { "x" : 948, "y" : -10 }, { "x" : 948, "y" : 1210 }, { "x" : 48, "y" : 1210 } ], "colour" : "#4684ee" }, { "id" : 69358, "reactomeId" : 11107568, "displayName" : "Transport of nucleotide sugars", "schemaClass" : "Pathway", "renderableClass" : "Shadow", "position" : { "x" : 533, "y" : 672 }, "minX" : 367, "maxX" : 699, "minY" : 595, "maxY" : 750, "prop" : { "x" : 367, "y" : 595, "width" : 332, "height" : 155 }, "points" : [ { "x" : 367, "y" : 595 }, { "x" : 699, "y" : 595 }, { "x" : 699, "y" : 750 }, { "x" : 367, "y" : 750 } ], "colour" : "#dc3912" } ], "minX" : 0, "maxX" : 1392, "minY" : 0, "maxY" : 1226, "disease" : false }