{
  "dbId" : 11079659,
  "stId" : "R-SPO-6804758",
  "speciesName" : "Schizosaccharomyces pombe",
  "nodes" : [ {
    "dbId" : 11071529,
    "stId" : "R-SPO-3215169-2",
    "displayName" : "ING5 [nucleoplasm]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 68324,
    "identifier" : "O74736",
    "standardIdentifier" : "uniprot:O74736",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 11071531 ],
    "children" : [ ]
  }, {
    "dbId" : 11071531,
    "stId" : "R-SPO-3215169-3",
    "displayName" : "Homologues of ING5 [nucleoplasm]",
    "schemaClass" : "DefinedSet",
    "speciesId" : 68324,
    "parents" : [ 11071549, 11071539 ],
    "children" : [ 11071527, 11071529 ]
  }, {
    "dbId" : 11065259,
    "stId" : "R-SPO-3215167-2",
    "displayName" : "ING2 [nucleoplasm]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 68324,
    "identifier" : "O74736",
    "standardIdentifier" : "uniprot:O74736",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 11065261 ],
    "children" : [ ]
  }, {
    "dbId" : 11071533,
    "stId" : "R-SPO-3318466",
    "displayName" : "nto1 [nucleoplasm]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 68324,
    "identifier" : "O74759",
    "standardIdentifier" : "uniprot:O74759",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "nto1" ],
    "parents" : [ 11071549, 11071539 ],
    "children" : [ ]
  }, {
    "dbId" : 11065261,
    "stId" : "R-SPO-3215167-3",
    "displayName" : "Homologues of ING2 [nucleoplasm]",
    "schemaClass" : "DefinedSet",
    "speciesId" : 68324,
    "diagramIds" : [ 21777 ],
    "parents" : [ 11072101 ],
    "children" : [ 11065254, 11065259 ]
  }, {
    "dbId" : 11073696,
    "stId" : "R-SPO-8877690",
    "displayName" : "p-S326-PIP4K2B dimers:PIN1 [nucleoplasm]",
    "schemaClass" : "Complex",
    "speciesId" : 68324,
    "diagramIds" : [ 21793 ],
    "parents" : [ ],
    "children" : [ 11061735, 11073691 ]
  }, {
    "dbId" : 11071525,
    "stId" : "R-SPO-3318448",
    "displayName" : "eaf6 [nucleoplasm]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 68324,
    "identifier" : "O14240",
    "standardIdentifier" : "uniprot:O14240",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "eaf6" ],
    "parents" : [ 11071549, 11071539 ],
    "children" : [ ]
  }, {
    "dbId" : 11065254,
    "stId" : "R-SPO-3215167",
    "displayName" : "ING2 [nucleoplasm]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 68324,
    "identifier" : "O42871",
    "standardIdentifier" : "uniprot:O42871",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 11065261 ],
    "children" : [ ]
  }, {
    "dbId" : 11071527,
    "stId" : "R-SPO-3215169",
    "displayName" : "ING5 [nucleoplasm]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 68324,
    "identifier" : "O42871",
    "standardIdentifier" : "uniprot:O42871",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 11071531 ],
    "children" : [ ]
  }, {
    "dbId" : 11071545,
    "stId" : "R-SPO-6805633-2",
    "displayName" : "phospho-p-T369-KAT6A [nucleoplasm]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 68324,
    "identifier" : "Q10325",
    "standardIdentifier" : "uniprot:Q10325",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 11071547 ],
    "children" : [ ]
  }, {
    "dbId" : 11071547,
    "stId" : "R-SPO-6805633-3",
    "displayName" : "Homologues of p-T369-KAT6A [nucleoplasm]",
    "schemaClass" : "DefinedSet",
    "speciesId" : 68324,
    "parents" : [ 11071549 ],
    "children" : [ 11071542, 11071545 ]
  }, {
    "dbId" : 11071549,
    "stId" : "R-SPO-6805636",
    "displayName" : "p-T369-KAT6A:ING5:MEAF6:BRPF1,(2,3) [nucleoplasm]",
    "schemaClass" : "Complex",
    "speciesId" : 68324,
    "diagramIds" : [ 21773 ],
    "parents" : [ ],
    "children" : [ 11071525, 11071533, 11071547, 11071531 ]
  }, {
    "dbId" : 11072318,
    "stId" : "R-SPO-6811503",
    "displayName" : "its3 [nucleoplasm]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 68324,
    "identifier" : "O13853",
    "standardIdentifier" : "uniprot:O13853",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "its3" ],
    "parents" : [ 11072324, 11072320, 11072330 ],
    "children" : [ ]
  }, {
    "dbId" : 11071539,
    "stId" : "R-SPO-6805616",
    "displayName" : "KAT6A:ING5:MEAF6:BRPF1,(2,3) [nucleoplasm]",
    "schemaClass" : "Complex",
    "speciesId" : 68324,
    "diagramIds" : [ 21772 ],
    "parents" : [ ],
    "children" : [ 11071525, 11066724, 11071533, 11071531 ]
  }, {
    "dbId" : 11071542,
    "stId" : "R-SPO-6805633",
    "displayName" : "phospho-p-T369-KAT6A [nucleoplasm]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 68324,
    "identifier" : "O94446",
    "standardIdentifier" : "uniprot:O94446",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 11071547 ],
    "children" : [ ]
  }, {
    "dbId" : 29358,
    "stId" : "R-ALL-29358",
    "displayName" : "ATP [nucleoplasm]",
    "schemaClass" : "SimpleEntity",
    "speciesId" : 0,
    "diagramIds" : [ 21781, 21771, 21787 ],
    "identifier" : "30616",
    "standardIdentifier" : "chebi:30616",
    "referenceType" : "ReferenceMolecule",
    "parents" : [ ],
    "children" : [ ]
  }, {
    "dbId" : 113582,
    "stId" : "R-ALL-113582",
    "displayName" : "ADP [nucleoplasm]",
    "schemaClass" : "SimpleEntity",
    "speciesId" : 0,
    "diagramIds" : [ 21782, 21789, 21774 ],
    "identifier" : "456216",
    "standardIdentifier" : "chebi:456216",
    "referenceType" : "ReferenceMolecule",
    "parents" : [ ],
    "children" : [ ]
  }, {
    "dbId" : 11061017,
    "stId" : "R-SPO-450258-3",
    "displayName" : "phospho-p-S207,T211-MAP2K6 [nucleoplasm]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 68324,
    "identifier" : "Q9Y884",
    "standardIdentifier" : "uniprot:Q9Y884",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 11061019 ],
    "children" : [ ]
  }, {
    "dbId" : 11073689,
    "stId" : "R-SPO-8877686",
    "displayName" : "p-S326-PIP4K2B:PIP4K2C [nucleoplasm]",
    "schemaClass" : "Complex",
    "speciesId" : 68324,
    "parents" : [ 11073691 ],
    "children" : [ 11073683, 11072328 ]
  }, {
    "dbId" : 11061019,
    "stId" : "R-SPO-450258-4",
    "displayName" : "Homologues of p-S207,T211-MAP2K6 [nucleoplasm]",
    "schemaClass" : "DefinedSet",
    "speciesId" : 68324,
    "diagramIds" : [ 21790 ],
    "parents" : [ ],
    "children" : [ 11061015, 11061013, 11061017 ]
  }, {
    "dbId" : 11073691,
    "stId" : "R-SPO-8877680",
    "displayName" : "p-S326-PIP4K2B dimers [nucleoplasm]",
    "schemaClass" : "CandidateSet",
    "speciesId" : 68324,
    "diagramIds" : [ 21788 ],
    "parents" : [ 11073696 ],
    "children" : [ 11073687, 11073685, 11073689 ]
  }, {
    "dbId" : 11073680,
    "stId" : "R-SPO-8877683",
    "displayName" : "PIP4K2B dimers [nucleoplasm]",
    "schemaClass" : "CandidateSet",
    "speciesId" : 68324,
    "diagramIds" : [ 21786 ],
    "parents" : [ ],
    "children" : [ 11072324, 11072320, 11072330 ]
  }, {
    "dbId" : 11073683,
    "stId" : "R-SPO-8877679",
    "displayName" : "phospho-its3 [nucleoplasm]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 68324,
    "identifier" : "O13853",
    "standardIdentifier" : "uniprot:O13853",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "its3" ],
    "parents" : [ 11073685, 11073687, 11073689 ],
    "children" : [ ]
  }, {
    "dbId" : 11061013,
    "stId" : "R-SPO-450258",
    "displayName" : "phospho-p-S207,T211-MAP2K6 [nucleoplasm]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 68324,
    "identifier" : "P10506",
    "standardIdentifier" : "uniprot:P10506",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 11061019 ],
    "children" : [ ]
  }, {
    "dbId" : 11073685,
    "stId" : "R-SPO-8877681",
    "displayName" : "PIP4K2A:p-S326-PIP4K2B [nucleoplasm]",
    "schemaClass" : "Complex",
    "speciesId" : 68324,
    "parents" : [ 11073691 ],
    "children" : [ 11073683, 11072322 ]
  }, {
    "dbId" : 11061015,
    "stId" : "R-SPO-450258-2",
    "displayName" : "phospho-p-S207,T211-MAP2K6 [nucleoplasm]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 68324,
    "identifier" : "P33886",
    "standardIdentifier" : "uniprot:P33886",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 11061019 ],
    "children" : [ ]
  }, {
    "dbId" : 11073687,
    "stId" : "R-SPO-8877687",
    "displayName" : "p-S326-PIP4K2B:p-S326-PIP4K2B [nucleoplasm]",
    "schemaClass" : "Complex",
    "speciesId" : 68324,
    "parents" : [ 11073691 ],
    "children" : [ 11073683 ]
  }, {
    "dbId" : 11066722,
    "stId" : "R-SPO-5603260-2",
    "displayName" : "KAT6A [nucleoplasm]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 68324,
    "identifier" : "Q10325",
    "standardIdentifier" : "uniprot:Q10325",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 11066724 ],
    "children" : [ ]
  }, {
    "dbId" : 6810412,
    "stId" : "R-ALL-6810412",
    "displayName" : "PI(4,5)P2 [nucleoplasm]",
    "schemaClass" : "SimpleEntity",
    "speciesId" : 0,
    "diagramIds" : [ 21783 ],
    "identifier" : "58456",
    "standardIdentifier" : "chebi:58456",
    "referenceType" : "ReferenceMolecule",
    "parents" : [ ],
    "children" : [ ]
  }, {
    "dbId" : 11066724,
    "stId" : "R-SPO-5603260-3",
    "displayName" : "Homologues of KAT6A [nucleoplasm]",
    "schemaClass" : "DefinedSet",
    "speciesId" : 68324,
    "parents" : [ 11071539 ],
    "children" : [ 11066722, 11066717 ]
  }, {
    "dbId" : 11072101,
    "stId" : "R-SPO-6810382",
    "displayName" : "ING2:PI5P [nuclear envelope]",
    "schemaClass" : "Complex",
    "speciesId" : 68324,
    "diagramIds" : [ 21779 ],
    "parents" : [ ],
    "children" : [ 6810408, 11065261 ]
  }, {
    "dbId" : 11061735,
    "stId" : "R-SPO-936016",
    "displayName" : "pin1 [nucleoplasm]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 68324,
    "diagramIds" : [ 21792 ],
    "identifier" : "O74448",
    "standardIdentifier" : "uniprot:O74448",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "pin1" ],
    "parents" : [ 11073696 ],
    "children" : [ ]
  }, {
    "dbId" : 6810408,
    "stId" : "R-ALL-6810408",
    "displayName" : "PI5P [nucleoplasm]",
    "schemaClass" : "SimpleEntity",
    "speciesId" : 0,
    "diagramIds" : [ 21778 ],
    "identifier" : "57795",
    "standardIdentifier" : "chebi:57795",
    "referenceType" : "ReferenceMolecule",
    "parents" : [ 11072101 ],
    "children" : [ ]
  }, {
    "dbId" : 11072328,
    "stId" : "R-SPO-6811499",
    "displayName" : "its3 [nucleoplasm]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 68324,
    "identifier" : "O13853",
    "standardIdentifier" : "uniprot:O13853",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "its3" ],
    "parents" : [ 11073689, 11072332, 11072334, 11072330 ],
    "children" : [ ]
  }, {
    "dbId" : 11072330,
    "stId" : "R-SPO-6811476",
    "displayName" : "PIP4K2B:PIP4K2C [nucleoplasm]",
    "schemaClass" : "Complex",
    "speciesId" : 68324,
    "parents" : [ 11073680, 11072336 ],
    "children" : [ 11072318, 11072328 ]
  }, {
    "dbId" : 11072332,
    "stId" : "R-SPO-6811465",
    "displayName" : "PIP4K2A:PIP4K2C [nucleoplasm]",
    "schemaClass" : "Complex",
    "speciesId" : 68324,
    "parents" : [ 11072336 ],
    "children" : [ 11072322, 11072328 ]
  }, {
    "dbId" : 11072334,
    "stId" : "R-SPO-6811471",
    "displayName" : "PIP4K2C:PIP4K2C [nucleoplasm]",
    "schemaClass" : "Complex",
    "speciesId" : 68324,
    "parents" : [ 11072336 ],
    "children" : [ 11072328 ]
  }, {
    "dbId" : 11058127,
    "stId" : "R-SPO-198357",
    "displayName" : "phospho-p-T308,S473-AKT1 [nucleoplasm]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 68324,
    "identifier" : "P50530",
    "standardIdentifier" : "uniprot:P50530",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 11058131 ],
    "children" : [ ]
  }, {
    "dbId" : 11072320,
    "stId" : "R-SPO-6811455",
    "displayName" : "PIP4K2B:PIP4K2B [nucleoplasm]",
    "schemaClass" : "Complex",
    "speciesId" : 68324,
    "parents" : [ 11073680, 11072336 ],
    "children" : [ 11072318 ]
  }, {
    "dbId" : 11072322,
    "stId" : "R-SPO-6811484",
    "displayName" : "its3 [nucleoplasm]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 68324,
    "identifier" : "O13853",
    "standardIdentifier" : "uniprot:O13853",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "its3" ],
    "parents" : [ 11073685, 11072324, 11072326, 11072332 ],
    "children" : [ ]
  }, {
    "dbId" : 11072324,
    "stId" : "R-SPO-6811452",
    "displayName" : "PIP4K2A:PIP4K2B [nucleoplasm]",
    "schemaClass" : "Complex",
    "speciesId" : 68324,
    "parents" : [ 11073680, 11072336 ],
    "children" : [ 11072322, 11072318 ]
  }, {
    "dbId" : 11072326,
    "stId" : "R-SPO-6811460",
    "displayName" : "PIP4K2A:PIP4K2A [nucleoplasm]",
    "schemaClass" : "Complex",
    "speciesId" : 68324,
    "parents" : [ 11072336 ],
    "children" : [ 11072322 ]
  }, {
    "dbId" : 11058137,
    "stId" : "R-SPO-3009365-2",
    "displayName" : "phospho-p-T305,S472-AKT3 [nucleoplasm]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 68324,
    "identifier" : "Q10364",
    "standardIdentifier" : "uniprot:Q10364",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 11058139 ],
    "children" : [ ]
  }, {
    "dbId" : 11058139,
    "stId" : "R-SPO-3009365-3",
    "displayName" : "Homologues of p-T305,S472-AKT3 [nucleoplasm]",
    "schemaClass" : "DefinedSet",
    "speciesId" : 68324,
    "parents" : [ 11058141 ],
    "children" : [ 11058135, 11058137 ]
  }, {
    "dbId" : 11058141,
    "stId" : "R-SPO-202072",
    "displayName" : "p-T,p-S-AKT [nucleoplasm]",
    "schemaClass" : "CandidateSet",
    "speciesId" : 68324,
    "diagramIds" : [ 21775 ],
    "parents" : [ ],
    "children" : [ 11058131, 11058133, 11058139 ]
  }, {
    "dbId" : 11066717,
    "stId" : "R-SPO-5603260",
    "displayName" : "KAT6A [nucleoplasm]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 68324,
    "identifier" : "O94446",
    "standardIdentifier" : "uniprot:O94446",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 11066724 ],
    "children" : [ ]
  }, {
    "dbId" : 11072336,
    "stId" : "R-SPO-6811466",
    "displayName" : "PIP4K2 dimers [nucleoplasm]",
    "schemaClass" : "CandidateSet",
    "speciesId" : 68324,
    "diagramIds" : [ 21784 ],
    "parents" : [ ],
    "children" : [ 11072326, 11072324, 11072320, 11072334, 11072332, 11072330 ]
  }, {
    "dbId" : 11058129,
    "stId" : "R-SPO-198357-2",
    "displayName" : "phospho-p-T308,S473-AKT1 [nucleoplasm]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 68324,
    "identifier" : "Q10364",
    "standardIdentifier" : "uniprot:Q10364",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 11058131 ],
    "children" : [ ]
  }, {
    "dbId" : 11058131,
    "stId" : "R-SPO-198357-3",
    "displayName" : "Homologues of p-T308,S473-AKT1 [nucleoplasm]",
    "schemaClass" : "DefinedSet",
    "speciesId" : 68324,
    "parents" : [ 11058141 ],
    "children" : [ 11058129, 11058127 ]
  }, {
    "dbId" : 11058133,
    "stId" : "R-SPO-202087",
    "displayName" : "phospho-p-T309,S474-AKT2 [nucleoplasm]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 68324,
    "identifier" : "P50530",
    "standardIdentifier" : "uniprot:P50530",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 11058141 ],
    "children" : [ ]
  }, {
    "dbId" : 11058135,
    "stId" : "R-SPO-3009365",
    "displayName" : "phospho-p-T305,S472-AKT3 [nucleoplasm]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 68324,
    "identifier" : "P50530",
    "standardIdentifier" : "uniprot:P50530",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 11058139 ],
    "children" : [ ]
  } ],
  "edges" : [ {
    "dbId" : 11073694,
    "stId" : "R-SPO-8877691",
    "displayName" : "MAP2K6 phosphorylates PIP4K2B",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "following" : [ 11073698 ],
    "inputs" : [ 29358, 11073680 ],
    "outputs" : [ 113582, 11073691 ],
    "catalysts" : [ 11061019 ],
    "efs" : [ ],
    "diagramIds" : [ 21785 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 11071551,
    "stId" : "R-SPO-6805640",
    "displayName" : "AKT phosphorylates KAT6A",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "inputs" : [ 29358, 11071539 ],
    "outputs" : [ 113582, 11071549 ],
    "catalysts" : [ 11058141 ],
    "efs" : [ ],
    "diagramIds" : [ 21770 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 11073698,
    "stId" : "R-SPO-8877692",
    "displayName" : "PIN1 binds phosphorylated PIP4K2B",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "preceding" : [ 11073694 ],
    "inputs" : [ 11061735, 11073691 ],
    "outputs" : [ 11073696 ],
    "efs" : [ ],
    "diagramIds" : [ 21791 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 11072339,
    "stId" : "R-SPO-6811522",
    "displayName" : "PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers in the nucleus",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "inputs" : [ 6810408, 29358 ],
    "outputs" : [ 113582, 6810412 ],
    "catalysts" : [ 11072336 ],
    "efs" : [ ],
    "diagramIds" : [ 21780 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 11072103,
    "stId" : "R-SPO-6810376",
    "displayName" : "ING2 binds PI5P",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "inputs" : [ 6810408, 11065261 ],
    "outputs" : [ 11072101 ],
    "efs" : [ ],
    "diagramIds" : [ 21776 ],
    "entityFunctionalStatus" : [ ]
  } ],
  "subpathways" : [ {
    "dbId" : 11079665,
    "stId" : "R-SPO-6811555",
    "displayName" : "PI5P Regulates TP53 Acetylation",
    "events" : [ 11073694, 11073698, 11072339, 11072103 ]
  } ]
}