{
  "dbId" : 11079549,
  "stableId" : "R-SPO-5688426",
  "displayName" : "Deubiquitination",
  "nodes" : [ {
    "id" : 41344,
    "reactomeId" : 11068154,
    "displayName" : "UCHL3,SENP8:NEDD8",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 848,
      "y" : 73
    },
    "minX" : 769,
    "maxX" : 904,
    "minY" : 49,
    "maxY" : 115,
    "prop" : {
      "x" : 799,
      "y" : 55,
      "width" : 99,
      "height" : 36
    },
    "textPosition" : {
      "x" : 800,
      "y" : 56
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 898,
          "y" : 55
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 898,
          "y" : 55
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 41340,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 814,
          "y" : 94
        },
        "to" : {
          "x" : 769,
          "y" : 115
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 809,
          "y" : 101
        },
        "b" : {
          "x" : 814,
          "y" : 94
        },
        "c" : {
          "x" : 806,
          "y" : 93
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 806,
          "y" : 93
        }
      }
    } ]
  }, {
    "id" : 41346,
    "reactomeId" : 11067989,
    "displayName" : "ubp6",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 289,
      "y" : 42
    },
    "minX" : 264,
    "maxX" : 356,
    "minY" : 25,
    "maxY" : 70,
    "prop" : {
      "x" : 264,
      "y" : 31,
      "width" : 50,
      "height" : 22
    },
    "textPosition" : {
      "x" : 269,
      "y" : 31
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 314,
          "y" : 31
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 314,
          "y" : 31
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 41345,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 317,
          "y" : 52
        },
        "to" : {
          "x" : 356,
          "y" : 70
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 41347,
    "reactomeId" : 11067991,
    "displayName" : "ADRM1:26S proteasome:USP14",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 486,
      "y" : 71
    },
    "minX" : 421,
    "maxX" : 557,
    "minY" : 47,
    "maxY" : 89,
    "prop" : {
      "x" : 421,
      "y" : 53,
      "width" : 130,
      "height" : 36
    },
    "textPosition" : {
      "x" : 421,
      "y" : 54
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 551,
          "y" : 53
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 551,
          "y" : 53
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 41345,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 41349,
    "reactomeId" : 11068885,
    "displayName" : "YOD1",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 145,
      "y" : 900
    },
    "minX" : 123,
    "maxX" : 199,
    "minY" : 878,
    "maxY" : 911,
    "prop" : {
      "x" : 123,
      "y" : 889,
      "width" : 44,
      "height" : 22
    },
    "textPosition" : {
      "x" : 124,
      "y" : 889
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 167,
          "y" : 889
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 167,
          "y" : 889
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 41348,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 170,
          "y" : 891
        },
        "to" : {
          "x" : 199,
          "y" : 878
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 41350,
    "reactomeId" : 11066353,
    "displayName" : "VCP",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 148,
      "y" : 852
    },
    "minX" : 132,
    "maxX" : 199,
    "minY" : 835,
    "maxY" : 878,
    "prop" : {
      "x" : 132,
      "y" : 841,
      "width" : 32,
      "height" : 22
    },
    "textPosition" : {
      "x" : 132,
      "y" : 841
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 164,
          "y" : 841
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 164,
          "y" : 841
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 41348,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 167,
          "y" : 860
        },
        "to" : {
          "x" : 199,
          "y" : 878
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 41351,
    "reactomeId" : 11068887,
    "displayName" : "YOD1:VCP",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 316,
      "y" : 876
    },
    "minX" : 273,
    "maxX" : 365,
    "minY" : 858,
    "maxY" : 888,
    "prop" : {
      "x" : 273,
      "y" : 864,
      "width" : 86,
      "height" : 24
    },
    "textPosition" : {
      "x" : 281,
      "y" : 867
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 359,
          "y" : 864
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 359,
          "y" : 864
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 41348,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 41353,
    "reactomeId" : 11068291,
    "displayName" : "Homologues of STAM",
    "schemaClass" : "DefinedSet",
    "renderableClass" : "EntitySet",
    "position" : {
      "x" : 92,
      "y" : 1662
    },
    "minX" : 72,
    "maxX" : 117,
    "minY" : 1651,
    "maxY" : 1694,
    "prop" : {
      "x" : 72,
      "y" : 1651,
      "width" : 41,
      "height" : 22
    },
    "textPosition" : {
      "x" : 72,
      "y" : 1624
    },
    "connectors" : [ {
      "edgeId" : 41352,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 100,
          "y" : 1676
        },
        "to" : {
          "x" : 117,
          "y" : 1694
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 41354,
    "reactomeId" : 11068296,
    "displayName" : "STAMBP",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 93,
      "y" : 1729
    },
    "minX" : 64,
    "maxX" : 128,
    "minY" : 1694,
    "maxY" : 1740,
    "prop" : {
      "x" : 64,
      "y" : 1718,
      "width" : 58,
      "height" : 22
    },
    "textPosition" : {
      "x" : 64,
      "y" : 1718
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 122,
          "y" : 1718
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 122,
          "y" : 1718
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 41352,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 100,
          "y" : 1715
        },
        "to" : {
          "x" : 117,
          "y" : 1694
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 41355,
    "reactomeId" : 11068298,
    "displayName" : "STAMBP:STAM",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 233,
      "y" : 1692
    },
    "minX" : 186,
    "maxX" : 286,
    "minY" : 1675,
    "maxY" : 1703,
    "prop" : {
      "x" : 186,
      "y" : 1681,
      "width" : 94,
      "height" : 22
    },
    "textPosition" : {
      "x" : 186,
      "y" : 1682
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 280,
          "y" : 1681
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 280,
          "y" : 1681
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 41352,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 41334,
    "reactomeId" : 11059328,
    "displayName" : "rpn1301",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 116,
      "y" : 64
    },
    "minX" : 91,
    "maxX" : 148,
    "minY" : 47,
    "maxY" : 99,
    "prop" : {
      "x" : 91,
      "y" : 53,
      "width" : 51,
      "height" : 22
    },
    "textPosition" : {
      "x" : 94,
      "y" : 47
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 142,
          "y" : 53
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 142,
          "y" : 53
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 41333,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 125,
          "y" : 78
        },
        "to" : {
          "x" : 146,
          "y" : 99
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 41335,
    "reactomeId" : 11059505,
    "displayName" : "26S proteasome",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 118,
      "y" : 144
    },
    "minX" : 62,
    "maxX" : 181,
    "minY" : 99,
    "maxY" : 155,
    "prop" : {
      "x" : 62,
      "y" : 133,
      "width" : 113,
      "height" : 22
    },
    "textPosition" : {
      "x" : 62,
      "y" : 134
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 175,
          "y" : 133
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 175,
          "y" : 133
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 41333,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 124,
          "y" : 130
        },
        "to" : {
          "x" : 146,
          "y" : 99
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 41336,
    "reactomeId" : 11067285,
    "displayName" : "ADRM1:26S proteasome",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 290,
      "y" : 100
    },
    "minX" : 248,
    "maxX" : 356,
    "minY" : 70,
    "maxY" : 133,
    "prop" : {
      "x" : 248,
      "y" : 82,
      "width" : 84,
      "height" : 36
    },
    "textPosition" : {
      "x" : 248,
      "y" : 83
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 332,
          "y" : 82
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 332,
          "y" : 82
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 41345,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 329,
          "y" : 79
        },
        "to" : {
          "x" : 356,
          "y" : 70
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 41333,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 41337,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 321,
          "y" : 121
        },
        "to" : {
          "x" : 348,
          "y" : 133
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 41338,
    "reactomeId" : 11067283,
    "displayName" : "uch2",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 284,
      "y" : 159
    },
    "minX" : 260,
    "maxX" : 348,
    "minY" : 133,
    "maxY" : 170,
    "prop" : {
      "x" : 260,
      "y" : 148,
      "width" : 49,
      "height" : 22
    },
    "textPosition" : {
      "x" : 265,
      "y" : 148
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 309,
          "y" : 148
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 309,
          "y" : 148
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 41337,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 312,
          "y" : 149
        },
        "to" : {
          "x" : 348,
          "y" : 133
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 41339,
    "reactomeId" : 11067287,
    "displayName" : "ADRM1:26S proteasome:UCHL5",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 488,
      "y" : 132
    },
    "minX" : 424,
    "maxX" : 559,
    "minY" : 108,
    "maxY" : 150,
    "prop" : {
      "x" : 424,
      "y" : 114,
      "width" : 129,
      "height" : 36
    },
    "textPosition" : {
      "x" : 424,
      "y" : 115
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 553,
          "y" : 114
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 553,
          "y" : 114
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 41337,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 41341,
    "reactomeId" : 11068150,
    "displayName" : "UCHL3,SENP8:NEDD8(1-88)",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 647,
      "y" : 72
    },
    "minX" : 598,
    "maxX" : 738,
    "minY" : 48,
    "maxY" : 115,
    "prop" : {
      "x" : 598,
      "y" : 54,
      "width" : 99,
      "height" : 36
    },
    "textPosition" : {
      "x" : 599,
      "y" : 55
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 697,
          "y" : 54
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 697,
          "y" : 54
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 41340,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 670,
          "y" : 93
        },
        "to" : {
          "x" : 704,
          "y" : 115
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 41340,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 700,
          "y" : 78
        },
        "to" : {
          "x" : 733,
          "y" : 83
        }
      }, {
        "from" : {
          "x" : 733,
          "y" : 83
        },
        "to" : {
          "x" : 733,
          "y" : 98
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 734,
          "y" : 102
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 734,
          "y" : 102
        }
      }
    } ]
  }, {
    "id" : 41342,
    "reactomeId" : 29356,
    "displayName" : "H2O",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 660,
      "y" : 150
    },
    "minX" : 638,
    "maxX" : 704,
    "minY" : 115,
    "maxY" : 165,
    "prop" : {
      "x" : 638,
      "y" : 135,
      "width" : 44,
      "height" : 30
    },
    "textPosition" : {
      "x" : 643,
      "y" : 139
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 677,
          "y" : 140
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 677,
          "y" : 140
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 41340,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 678,
          "y" : 132
        },
        "to" : {
          "x" : 704,
          "y" : 115
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ],
    "trivial" : true
  }, {
    "id" : 41343,
    "reactomeId" : 11068156,
    "displayName" : "ubl1",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 838,
      "y" : 143
    },
    "minX" : 769,
    "maxX" : 895,
    "minY" : 115,
    "maxY" : 154,
    "prop" : {
      "x" : 788,
      "y" : 132,
      "width" : 101,
      "height" : 22
    },
    "textPosition" : {
      "x" : 821,
      "y" : 132
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 889,
          "y" : 132
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 889,
          "y" : 132
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 41340,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 810,
          "y" : 129
        },
        "to" : {
          "x" : 769,
          "y" : 115
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 802,
          "y" : 131
        },
        "b" : {
          "x" : 810,
          "y" : 129
        },
        "c" : {
          "x" : 805,
          "y" : 123
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 805,
          "y" : 123
        }
      }
    } ]
  } ],
  "edges" : [ {
    "id" : 41345,
    "reactomeId" : 11067993,
    "displayName" : "ADRM1:26S proteaseome binds USP14",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 385,
      "y" : 70
    },
    "minX" : 356,
    "maxX" : 418,
    "minY" : 64,
    "maxY" : 76,
    "reactionType" : "binding",
    "segments" : [ {
      "from" : {
        "x" : 356,
        "y" : 70
      },
      "to" : {
        "x" : 385,
        "y" : 70
      }
    }, {
      "from" : {
        "x" : 385,
        "y" : 70
      },
      "to" : {
        "x" : 418,
        "y" : 70
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 411,
        "y" : 74
      },
      "b" : {
        "x" : 418,
        "y" : 70
      },
      "c" : {
        "x" : 411,
        "y" : 66
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 411,
        "y" : 66
      }
    },
    "reactionShape" : {
      "c" : {
        "x" : 385,
        "y" : 70
      },
      "r" : 5,
      "type" : "CIRCLE",
      "centre" : {
        "x" : 385,
        "y" : 70
      }
    },
    "inputs" : [ {
      "id" : 41336,
      "points" : [ {
        "x" : 329,
        "y" : 79
      } ]
    }, {
      "id" : 41346,
      "points" : [ {
        "x" : 317,
        "y" : 52
      } ]
    } ],
    "outputs" : [ {
      "id" : 41347
    } ]
  }, {
    "id" : 41348,
    "reactomeId" : 11068889,
    "displayName" : "YOD1 binds VCP",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 241,
      "y" : 878
    },
    "minX" : 199,
    "maxX" : 270,
    "minY" : 872,
    "maxY" : 884,
    "reactionType" : "binding",
    "segments" : [ {
      "from" : {
        "x" : 199,
        "y" : 878
      },
      "to" : {
        "x" : 241,
        "y" : 878
      }
    }, {
      "from" : {
        "x" : 241,
        "y" : 878
      },
      "to" : {
        "x" : 270,
        "y" : 877
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 263,
        "y" : 881
      },
      "b" : {
        "x" : 270,
        "y" : 877
      },
      "c" : {
        "x" : 263,
        "y" : 873
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 263,
        "y" : 873
      }
    },
    "reactionShape" : {
      "c" : {
        "x" : 241,
        "y" : 878
      },
      "r" : 5,
      "type" : "CIRCLE",
      "centre" : {
        "x" : 241,
        "y" : 878
      }
    },
    "inputs" : [ {
      "id" : 41349,
      "points" : [ {
        "x" : 170,
        "y" : 891
      } ]
    }, {
      "id" : 41350,
      "points" : [ {
        "x" : 167,
        "y" : 860
      } ]
    } ],
    "outputs" : [ {
      "id" : 41351
    } ]
  }, {
    "id" : 41333,
    "reactomeId" : 11067312,
    "displayName" : "ADRM1 binds 26S proteasome",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 193,
      "y" : 99
    },
    "minX" : 146,
    "maxX" : 245,
    "minY" : 93,
    "maxY" : 105,
    "reactionType" : "binding",
    "segments" : [ {
      "from" : {
        "x" : 146,
        "y" : 99
      },
      "to" : {
        "x" : 193,
        "y" : 99
      }
    }, {
      "from" : {
        "x" : 193,
        "y" : 99
      },
      "to" : {
        "x" : 245,
        "y" : 99
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 238,
        "y" : 103
      },
      "b" : {
        "x" : 245,
        "y" : 99
      },
      "c" : {
        "x" : 238,
        "y" : 95
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 238,
        "y" : 95
      }
    },
    "reactionShape" : {
      "c" : {
        "x" : 193,
        "y" : 99
      },
      "r" : 5,
      "type" : "CIRCLE",
      "centre" : {
        "x" : 193,
        "y" : 99
      }
    },
    "inputs" : [ {
      "id" : 41334,
      "points" : [ {
        "x" : 125,
        "y" : 78
      } ]
    }, {
      "id" : 41335,
      "points" : [ {
        "x" : 124,
        "y" : 130
      } ]
    } ],
    "outputs" : [ {
      "id" : 41336
    } ]
  }, {
    "id" : 41352,
    "reactomeId" : 11068300,
    "displayName" : "STAMBP binds STAM",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 143,
      "y" : 1694
    },
    "minX" : 117,
    "maxX" : 183,
    "minY" : 1688,
    "maxY" : 1700,
    "reactionType" : "binding",
    "segments" : [ {
      "from" : {
        "x" : 117,
        "y" : 1694
      },
      "to" : {
        "x" : 143,
        "y" : 1694
      }
    }, {
      "from" : {
        "x" : 143,
        "y" : 1694
      },
      "to" : {
        "x" : 183,
        "y" : 1693
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 176,
        "y" : 1697
      },
      "b" : {
        "x" : 183,
        "y" : 1693
      },
      "c" : {
        "x" : 176,
        "y" : 1689
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 176,
        "y" : 1689
      }
    },
    "reactionShape" : {
      "c" : {
        "x" : 143,
        "y" : 1694
      },
      "r" : 5,
      "type" : "CIRCLE",
      "centre" : {
        "x" : 143,
        "y" : 1694
      }
    },
    "inputs" : [ {
      "id" : 41353,
      "points" : [ {
        "x" : 100,
        "y" : 1676
      } ]
    }, {
      "id" : 41354,
      "points" : [ {
        "x" : 100,
        "y" : 1715
      } ]
    } ],
    "outputs" : [ {
      "id" : 41355
    } ]
  }, {
    "id" : 41337,
    "reactomeId" : 11067289,
    "displayName" : "ADRM1:26S proteaseome binds UCHL5",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 383,
      "y" : 134
    },
    "minX" : 348,
    "maxX" : 421,
    "minY" : 128,
    "maxY" : 140,
    "reactionType" : "binding",
    "segments" : [ {
      "from" : {
        "x" : 348,
        "y" : 133
      },
      "to" : {
        "x" : 383,
        "y" : 134
      }
    }, {
      "from" : {
        "x" : 383,
        "y" : 134
      },
      "to" : {
        "x" : 421,
        "y" : 133
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 414,
        "y" : 137
      },
      "b" : {
        "x" : 421,
        "y" : 133
      },
      "c" : {
        "x" : 414,
        "y" : 129
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 414,
        "y" : 129
      }
    },
    "reactionShape" : {
      "c" : {
        "x" : 383,
        "y" : 134
      },
      "r" : 5,
      "type" : "CIRCLE",
      "centre" : {
        "x" : 383,
        "y" : 134
      }
    },
    "inputs" : [ {
      "id" : 41336,
      "points" : [ {
        "x" : 321,
        "y" : 121
      } ]
    }, {
      "id" : 41338,
      "points" : [ {
        "x" : 312,
        "y" : 149
      } ]
    } ],
    "outputs" : [ {
      "id" : 41339
    } ]
  }, {
    "id" : 41340,
    "reactomeId" : 11068159,
    "displayName" : "UCHL3, SENP8 cleave NEDD8",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 734,
      "y" : 114
    },
    "minX" : 704,
    "maxX" : 769,
    "minY" : 108,
    "maxY" : 120,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 704,
        "y" : 115
      },
      "to" : {
        "x" : 734,
        "y" : 114
      }
    }, {
      "from" : {
        "x" : 734,
        "y" : 114
      },
      "to" : {
        "x" : 769,
        "y" : 115
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 728,
        "y" : 108
      },
      "b" : {
        "x" : 740,
        "y" : 120
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 734,
        "y" : 114
      }
    },
    "inputs" : [ {
      "id" : 41341,
      "points" : [ {
        "x" : 670,
        "y" : 93
      } ]
    }, {
      "id" : 41342,
      "points" : [ {
        "x" : 678,
        "y" : 132
      } ]
    } ],
    "outputs" : [ {
      "id" : 41343,
      "points" : [ {
        "x" : 810,
        "y" : 129
      } ]
    }, {
      "id" : 41344,
      "points" : [ {
        "x" : 814,
        "y" : 94
      } ]
    } ],
    "catalysts" : [ {
      "id" : 41341,
      "points" : [ {
        "x" : 700,
        "y" : 78
      }, {
        "x" : 733,
        "y" : 83
      } ]
    } ]
  } ],
  "compartments" : [ {
    "id" : 41410,
    "reactomeId" : 5460,
    "displayName" : "mitochondrial matrix",
    "schemaClass" : "Compartment",
    "renderableClass" : "Compartment",
    "position" : {
      "x" : 1628,
      "y" : 899
    },
    "minX" : 1498,
    "maxX" : 1758,
    "minY" : 796,
    "maxY" : 1002,
    "prop" : {
      "x" : 1498,
      "y" : 796,
      "width" : 260,
      "height" : 206
    },
    "textPosition" : {
      "x" : 1522,
      "y" : 888
    },
    "insets" : {
      "x" : 1508,
      "y" : 806,
      "width" : 240,
      "height" : 186
    },
    "bgColor" : {
      "r" : 250,
      "g" : 240,
      "b" : 240
    }
  }, {
    "id" : 41356,
    "reactomeId" : 70101,
    "displayName" : "cytosol",
    "schemaClass" : "Compartment",
    "renderableClass" : "Compartment",
    "position" : {
      "x" : 1685,
      "y" : 933
    },
    "minX" : 0,
    "maxX" : 3371,
    "minY" : 0,
    "maxY" : 1866,
    "prop" : {
      "x" : 0,
      "y" : 0,
      "width" : 3371,
      "height" : 1866
    },
    "textPosition" : {
      "x" : 80,
      "y" : 1810
    },
    "insets" : {
      "x" : 10,
      "y" : 10,
      "width" : 3351,
      "height" : 1846
    },
    "bgColor" : {
      "r" : 250,
      "g" : 240,
      "b" : 240
    },
    "componentIds" : [ 41333, 41334, 41335, 41357, 41336, 41337, 41338, 41339, 41340, 41341, 41342, 41343, 41344, 41345, 41346, 41347, 41391, 41349, 41410, 41354, 41355, 41352, 41353, 41350, 41348, 41351, 41436 ]
  }, {
    "id" : 41436,
    "reactomeId" : 17957,
    "displayName" : "endoplasmic reticulum lumen",
    "schemaClass" : "Compartment",
    "renderableClass" : "Compartment",
    "position" : {
      "x" : 1602,
      "y" : 1588
    },
    "minX" : 1477,
    "maxX" : 1727,
    "minY" : 1463,
    "maxY" : 1713,
    "prop" : {
      "x" : 1477,
      "y" : 1463,
      "width" : 250,
      "height" : 250
    },
    "textPosition" : {
      "x" : 1497,
      "y" : 1664
    },
    "insets" : {
      "x" : 1487,
      "y" : 1473,
      "width" : 230,
      "height" : 230
    },
    "bgColor" : {
      "r" : 250,
      "g" : 240,
      "b" : 240
    }
  }, {
    "id" : 41357,
    "reactomeId" : 7660,
    "displayName" : "nucleoplasm",
    "schemaClass" : "Compartment",
    "renderableClass" : "Compartment",
    "position" : {
      "x" : 2632,
      "y" : 898
    },
    "minX" : 1930,
    "maxX" : 3335,
    "minY" : 23,
    "maxY" : 1774,
    "prop" : {
      "x" : 1930,
      "y" : 23,
      "width" : 1405,
      "height" : 1751
    },
    "textPosition" : {
      "x" : 1951,
      "y" : 1725
    },
    "insets" : {
      "x" : 1940,
      "y" : 33,
      "width" : 1385,
      "height" : 1731
    },
    "bgColor" : {
      "r" : 250,
      "g" : 240,
      "b" : 240
    }
  }, {
    "id" : 41391,
    "reactomeId" : 171907,
    "displayName" : "endosome lumen",
    "schemaClass" : "Compartment",
    "renderableClass" : "Compartment",
    "position" : {
      "x" : 748,
      "y" : 1031
    },
    "minX" : 623,
    "maxX" : 873,
    "minY" : 930,
    "maxY" : 1133,
    "prop" : {
      "x" : 623,
      "y" : 930,
      "width" : 250,
      "height" : 203
    },
    "textPosition" : {
      "x" : 693,
      "y" : 1082
    },
    "insets" : {
      "x" : 633,
      "y" : 940,
      "width" : 230,
      "height" : 183
    },
    "bgColor" : {
      "r" : 250,
      "g" : 240,
      "b" : 240
    }
  } ],
  "notes" : [ ],
  "links" : [ ],
  "shadows" : [ {
    "id" : 41440,
    "reactomeId" : 11079601,
    "displayName" : "Ovarian tumor domain proteases",
    "schemaClass" : "Pathway",
    "renderableClass" : "Shadow",
    "position" : {
      "x" : 241,
      "y" : 876
    },
    "minX" : 113,
    "maxX" : 369,
    "minY" : 831,
    "maxY" : 921,
    "prop" : {
      "x" : 113,
      "y" : 831,
      "width" : 256,
      "height" : 90
    },
    "points" : [ {
      "x" : 113,
      "y" : 831
    }, {
      "x" : 369,
      "y" : 831
    }, {
      "x" : 369,
      "y" : 921
    }, {
      "x" : 113,
      "y" : 921
    } ],
    "colour" : "#666666"
  }, {
    "id" : 41437,
    "reactomeId" : 11079547,
    "displayName" : "UCH proteinases",
    "schemaClass" : "Pathway",
    "renderableClass" : "Shadow",
    "position" : {
      "x" : 480,
      "y" : 111
    },
    "minX" : 52,
    "maxX" : 908,
    "minY" : 43,
    "maxY" : 180,
    "prop" : {
      "x" : 52,
      "y" : 128,
      "width" : 856,
      "height" : 52
    },
    "points" : [ {
      "x" : 52,
      "y" : 43
    }, {
      "x" : 908,
      "y" : 43
    }, {
      "x" : 908,
      "y" : 180
    }, {
      "x" : 52,
      "y" : 180
    } ],
    "colour" : "#4684ee"
  }, {
    "id" : 41438,
    "reactomeId" : 11079569,
    "displayName" : "Ub-specific processing proteases",
    "schemaClass" : "Pathway",
    "renderableClass" : "Shadow",
    "position" : {
      "x" : 399,
      "y" : 74
    },
    "minX" : 238,
    "maxX" : 561,
    "minY" : 21,
    "maxY" : 128,
    "prop" : {
      "x" : 238,
      "y" : 21,
      "width" : 323,
      "height" : 107
    },
    "points" : [ {
      "x" : 238,
      "y" : 21
    }, {
      "x" : 561,
      "y" : 21
    }, {
      "x" : 561,
      "y" : 128
    }, {
      "x" : 238,
      "y" : 128
    } ],
    "colour" : "#dc3912"
  }, {
    "id" : 41439,
    "reactomeId" : 11079581,
    "displayName" : "Metalloprotease DUBs",
    "schemaClass" : "Pathway",
    "renderableClass" : "Shadow",
    "position" : {
      "x" : 172,
      "y" : 1695
    },
    "minX" : 54,
    "maxX" : 290,
    "minY" : 1641,
    "maxY" : 1750,
    "prop" : {
      "x" : 54,
      "y" : 1641,
      "width" : 236,
      "height" : 109
    },
    "points" : [ {
      "x" : 54,
      "y" : 1641
    }, {
      "x" : 290,
      "y" : 1641
    }, {
      "x" : 290,
      "y" : 1750
    }, {
      "x" : 54,
      "y" : 1750
    } ],
    "colour" : "#008000"
  } ],
  "minX" : 0,
  "maxX" : 3371,
  "minY" : 0,
  "maxY" : 1866,
  "disease" : false
}