{
  "dbId" : 11050934,
  "stId" : "R-DDI-9833482",
  "speciesName" : "Dictyostelium discoideum",
  "nodes" : [ {
    "dbId" : 11012264,
    "stId" : "R-DDI-167998",
    "displayName" : "MAP2K6 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 170941,
    "diagramIds" : [ 151161 ],
    "identifier" : "Q54HS0",
    "standardIdentifier" : "uniprot:Q54HS0",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ ],
    "children" : [ ]
  }, {
    "dbId" : 11008933,
    "stId" : "R-DDI-539044-2",
    "displayName" : "STAT3 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 170941,
    "identifier" : "Q54B81",
    "standardIdentifier" : "uniprot:Q54B81",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 11008960 ],
    "children" : [ ]
  }, {
    "dbId" : 11008928,
    "stId" : "R-DDI-539044",
    "displayName" : "dstA [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 170941,
    "identifier" : "O00910",
    "standardIdentifier" : "uniprot:O00910",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "dstA" ],
    "parents" : [ 11008960 ],
    "children" : [ ]
  }, {
    "dbId" : 11049632,
    "stId" : "R-DDI-194138",
    "displayName" : "Signaling by VEGF",
    "schemaClass" : "Pathway",
    "speciesId" : 170941,
    "diagramIds" : [ 151214 ]
  }, {
    "dbId" : 11008943,
    "stId" : "R-DDI-539044-4",
    "displayName" : "STAT3 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 170941,
    "identifier" : "Q54GL9",
    "standardIdentifier" : "uniprot:Q54GL9",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 11008960 ],
    "children" : [ ]
  }, {
    "dbId" : 11050146,
    "stId" : "R-DDI-1169408",
    "displayName" : "ISG15 antiviral mechanism",
    "schemaClass" : "Pathway",
    "speciesId" : 170941,
    "diagramIds" : [ 151213 ]
  }, {
    "dbId" : 11008938,
    "stId" : "R-DDI-539044-3",
    "displayName" : "dstC [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 170941,
    "identifier" : "Q54BD4",
    "standardIdentifier" : "uniprot:Q54BD4",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "dstC" ],
    "parents" : [ 11008960 ],
    "children" : [ ]
  }, {
    "dbId" : 11008948,
    "stId" : "R-DDI-539044-5",
    "displayName" : "STAT3 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 170941,
    "identifier" : "Q54WB7",
    "standardIdentifier" : "uniprot:Q54WB7",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 11008960 ],
    "children" : [ ]
  }, {
    "dbId" : 11008958,
    "stId" : "R-DDI-539044-7",
    "displayName" : "dstD [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 170941,
    "identifier" : "Q86I20",
    "standardIdentifier" : "uniprot:Q86I20",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "dstD" ],
    "parents" : [ 11008960 ],
    "children" : [ ]
  }, {
    "dbId" : 11009468,
    "stId" : "R-DDI-196235",
    "displayName" : "psrA [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 170941,
    "identifier" : "Q54VB6",
    "standardIdentifier" : "uniprot:Q54VB6",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "psrA" ],
    "parents" : [ 11047284 ],
    "children" : [ ]
  }, {
    "dbId" : 9836685,
    "stId" : "R-ALL-9836685",
    "displayName" : "luteolin [cytosol]",
    "schemaClass" : "ChemicalDrug",
    "speciesId" : 0,
    "identifier" : "5215",
    "standardIdentifier" : "iuphar.ligand:5215",
    "chebiIdentifier" : "chebi:15864",
    "parents" : [ 9836704 ],
    "children" : [ ]
  }, {
    "dbId" : 11042486,
    "stId" : "R-DDI-1112559",
    "displayName" : "STAT1, STAT3 [cytosol]",
    "schemaClass" : "DefinedSet",
    "speciesId" : 170941,
    "diagramIds" : [ 151154 ],
    "parents" : [ 11047230 ],
    "children" : [ 11008960, 11008994 ]
  }, {
    "dbId" : 11008953,
    "stId" : "R-DDI-539044-6",
    "displayName" : "dstB [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 170941,
    "identifier" : "Q70GP4",
    "standardIdentifier" : "uniprot:Q70GP4",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "dstB" ],
    "parents" : [ 11008960 ],
    "children" : [ ]
  }, {
    "dbId" : 76577,
    "stId" : "R-ALL-76577",
    "displayName" : "AMP [cytosol]",
    "schemaClass" : "SimpleEntity",
    "speciesId" : 0,
    "diagramIds" : [ 151143 ],
    "identifier" : "456215",
    "standardIdentifier" : "chebi:456215",
    "referenceType" : "ReferenceMolecule",
    "parents" : [ ],
    "children" : [ ]
  }, {
    "dbId" : 11008903,
    "stId" : "R-DDI-190532",
    "displayName" : "TUBB3 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 170941,
    "identifier" : "P32256",
    "standardIdentifier" : "uniprot:P32256",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 11008913 ],
    "children" : [ ]
  }, {
    "dbId" : 11008898,
    "stId" : "R-DDI-190509",
    "displayName" : "alpha-tubulin:GTP [cytosol]",
    "schemaClass" : "Complex",
    "speciesId" : 170941,
    "parents" : [ 11008917 ],
    "children" : [ 29438, 11008896 ]
  }, {
    "dbId" : 11050382,
    "stId" : "R-DDI-1834949",
    "displayName" : "Cytosolic sensors of pathogen-associated DNA ",
    "schemaClass" : "Pathway",
    "speciesId" : 170941,
    "diagramIds" : [ 151216 ]
  }, {
    "dbId" : 11008896,
    "stId" : "R-DDI-190587",
    "displayName" : "alpha-tubulin [cytosol]",
    "schemaClass" : "CandidateSet",
    "speciesId" : 170941,
    "parents" : [ 11008898 ],
    "children" : [ 11008888, 11008876, 11008894, 11008882, 11008884 ]
  }, {
    "dbId" : 11008911,
    "stId" : "R-DDI-191698",
    "displayName" : "TUBB6 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 170941,
    "identifier" : "P32256",
    "standardIdentifier" : "uniprot:P32256",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 11008913 ],
    "children" : [ ]
  }, {
    "dbId" : 11008909,
    "stId" : "R-DDI-191703",
    "displayName" : "TUBB1 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 170941,
    "identifier" : "P32256",
    "standardIdentifier" : "uniprot:P32256",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 11008913 ],
    "children" : [ ]
  }, {
    "dbId" : 11008907,
    "stId" : "R-DDI-191702",
    "displayName" : "TUBB4B [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 170941,
    "identifier" : "P32256",
    "standardIdentifier" : "uniprot:P32256",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 11008913 ],
    "children" : [ ]
  }, {
    "dbId" : 11008905,
    "stId" : "R-DDI-190588",
    "displayName" : "TUBB4A [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 170941,
    "identifier" : "P32256",
    "standardIdentifier" : "uniprot:P32256",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 11008913 ],
    "children" : [ ]
  }, {
    "dbId" : 11008919,
    "stId" : "R-DDI-8982424",
    "displayName" : "Microtubule protofilament [cytosol]",
    "schemaClass" : "Polymer",
    "speciesId" : 170941,
    "parents" : [ 11008921 ],
    "children" : [ 11008917 ]
  }, {
    "dbId" : 11008917,
    "stId" : "R-DDI-190570",
    "displayName" : "alpha-beta tubulin dimer [cytosol]",
    "schemaClass" : "Complex",
    "speciesId" : 170941,
    "parents" : [ 11008919 ],
    "children" : [ 11008898, 11008915 ]
  }, {
    "dbId" : 11008915,
    "stId" : "R-DDI-190512",
    "displayName" : "beta-tubulin:GDP [cytosol]",
    "schemaClass" : "Complex",
    "speciesId" : 170941,
    "parents" : [ 11008917 ],
    "children" : [ 29420, 11008913 ]
  }, {
    "dbId" : 11008913,
    "stId" : "R-DDI-190502",
    "displayName" : "beta-tubulin [cytosol]",
    "schemaClass" : "CandidateSet",
    "speciesId" : 170941,
    "parents" : [ 11008915 ],
    "children" : [ 11008905, 11008907, 11008909, 11008911, 11008903 ]
  }, {
    "dbId" : 170292,
    "stId" : "R-ALL-170292",
    "displayName" : "ssRNA [cytosol]",
    "schemaClass" : "OtherEntity",
    "speciesId" : 0,
    "parents" : [ 9833766 ],
    "children" : [ ]
  }, {
    "dbId" : 9836704,
    "stId" : "R-ALL-9836704",
    "displayName" : "PKR inhibitors [cytosol]",
    "schemaClass" : "DefinedSet",
    "speciesId" : 0,
    "diagramIds" : [ 151185 ],
    "parents" : [ 11047293 ],
    "children" : [ 9836685, 9669720 ]
  }, {
    "dbId" : 11050896,
    "stId" : "R-DDI-909733",
    "displayName" : "Interferon alpha/beta signaling",
    "schemaClass" : "Pathway",
    "speciesId" : 170941,
    "diagramIds" : [ 151212 ]
  }, {
    "dbId" : 11008921,
    "stId" : "R-DDI-190599",
    "displayName" : "Microtubule [cytosol]",
    "schemaClass" : "Complex",
    "speciesId" : 170941,
    "diagramIds" : [ 151169 ],
    "parents" : [ 11047245 ],
    "children" : [ 11008919 ]
  }, {
    "dbId" : 11047145,
    "stId" : "R-DDI-9833834-2",
    "displayName" : "phospho-p-EIF2AK2 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 170941,
    "identifier" : "Q55DK2",
    "standardIdentifier" : "uniprot:Q55DK2",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 11047147 ],
    "children" : [ ]
  }, {
    "dbId" : 11047147,
    "stId" : "R-DDI-9833834-3",
    "displayName" : "Homologues of p-EIF2AK2 [cytosol]",
    "schemaClass" : "DefinedSet",
    "speciesId" : 170941,
    "parents" : [ 11047149 ],
    "children" : [ 11047132, 11047145 ]
  }, {
    "dbId" : 11047149,
    "stId" : "R-DDI-9833821",
    "displayName" : "p-EIF2AK2 dimer [cytosol]",
    "schemaClass" : "Complex",
    "speciesId" : 170941,
    "diagramIds" : [ 151133 ],
    "parents" : [ ],
    "children" : [ 11047147 ]
  }, {
    "dbId" : 11008994,
    "stId" : "R-DDI-629622-8",
    "displayName" : "Homologues of STAT1 [cytosol]",
    "schemaClass" : "DefinedSet",
    "speciesId" : 170941,
    "parents" : [ 11042486 ],
    "children" : [ 11008984, 11008986, 11008988, 11008990, 11008992, 11008980, 11008982 ]
  }, {
    "dbId" : 11008992,
    "stId" : "R-DDI-629622-7",
    "displayName" : "dstD [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 170941,
    "identifier" : "Q86I20",
    "standardIdentifier" : "uniprot:Q86I20",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "dstD" ],
    "parents" : [ 11008994 ],
    "children" : [ ]
  }, {
    "dbId" : 11047151,
    "stId" : "R-DDI-9836332",
    "displayName" : "phospho-p-EIF2AK2 [nucleoplasm]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 170941,
    "identifier" : "Q54R98",
    "standardIdentifier" : "uniprot:Q54R98",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 11047155 ],
    "children" : [ ]
  }, {
    "dbId" : 11047161,
    "stId" : "R-DDI-9833725",
    "displayName" : "EIF2AK2 dimer [cytosol]",
    "schemaClass" : "Complex",
    "speciesId" : 170941,
    "parents" : [ 11047217, 11047163 ],
    "children" : [ 11015739 ]
  }, {
    "dbId" : 11047163,
    "stId" : "R-DDI-9833735",
    "displayName" : "EIF2AK2 dimer:Host RNA activators [cytosol]",
    "schemaClass" : "Complex",
    "speciesId" : 170941,
    "diagramIds" : [ 151138 ],
    "parents" : [ ],
    "children" : [ 11047161, 9833766 ]
  }, {
    "dbId" : 11047153,
    "stId" : "R-DDI-9836332-2",
    "displayName" : "phospho-p-EIF2AK2 [nucleoplasm]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 170941,
    "identifier" : "Q55DK2",
    "standardIdentifier" : "uniprot:Q55DK2",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 11047155 ],
    "children" : [ ]
  }, {
    "dbId" : 11047155,
    "stId" : "R-DDI-9836332-3",
    "displayName" : "Homologues of p-EIF2AK2 [nucleoplasm]",
    "schemaClass" : "DefinedSet",
    "speciesId" : 170941,
    "parents" : [ 11047157 ],
    "children" : [ 11047153, 11047151 ]
  }, {
    "dbId" : 11047157,
    "stId" : "R-DDI-9836331",
    "displayName" : "p-EIF2AK2 dimer [nucleoplasm]",
    "schemaClass" : "Complex",
    "speciesId" : 170941,
    "diagramIds" : [ 151134 ],
    "parents" : [ ],
    "children" : [ 11047155 ]
  }, {
    "dbId" : 11008960,
    "stId" : "R-DDI-539044-8",
    "displayName" : "Homologues of STAT3 [cytosol]",
    "schemaClass" : "DefinedSet",
    "speciesId" : 170941,
    "parents" : [ 11042486 ],
    "children" : [ 11008953, 11008938, 11008958, 11008943, 11008928, 11008948, 11008933 ]
  }, {
    "dbId" : 11009486,
    "stId" : "R-DDI-165971",
    "displayName" : "PPP2CA [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 170941,
    "identifier" : "Q9XZE5",
    "standardIdentifier" : "uniprot:Q9XZE5",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 11009488 ],
    "children" : [ ]
  }, {
    "dbId" : 11009484,
    "stId" : "R-DDI-165990",
    "displayName" : "PP2A-subunit A [cytosol]",
    "schemaClass" : "CandidateSet",
    "speciesId" : 170941,
    "parents" : [ 11047289, 11047284 ],
    "children" : [ 11009480 ]
  }, {
    "dbId" : 11009480,
    "stId" : "R-DDI-165982",
    "displayName" : "pppA [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 170941,
    "identifier" : "Q54QR9",
    "standardIdentifier" : "uniprot:Q54QR9",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "pppA" ],
    "parents" : [ 11009484 ],
    "children" : [ ]
  }, {
    "dbId" : 11008982,
    "stId" : "R-DDI-629622-2",
    "displayName" : "STAT1 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 170941,
    "identifier" : "Q54B81",
    "standardIdentifier" : "uniprot:Q54B81",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 11008994 ],
    "children" : [ ]
  }, {
    "dbId" : 11008980,
    "stId" : "R-DDI-629622",
    "displayName" : "dstA [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 170941,
    "identifier" : "O00910",
    "standardIdentifier" : "uniprot:O00910",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "dstA" ],
    "parents" : [ 11008994 ],
    "children" : [ ]
  }, {
    "dbId" : 11047132,
    "stId" : "R-DDI-9833834",
    "displayName" : "phospho-p-EIF2AK2 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 170941,
    "identifier" : "Q54R98",
    "standardIdentifier" : "uniprot:Q54R98",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 11047147 ],
    "children" : [ ]
  }, {
    "dbId" : 11009488,
    "stId" : "R-DDI-165977",
    "displayName" : "PP2A-catalytic subunit C [cytosol]",
    "schemaClass" : "CandidateSet",
    "speciesId" : 170941,
    "parents" : [ 11047289, 11047284 ],
    "children" : [ 11009486 ]
  }, {
    "dbId" : 11008990,
    "stId" : "R-DDI-629622-6",
    "displayName" : "dstB [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 170941,
    "identifier" : "Q70GP4",
    "standardIdentifier" : "uniprot:Q70GP4",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "dstB" ],
    "parents" : [ 11008994 ],
    "children" : [ ]
  }, {
    "dbId" : 11008988,
    "stId" : "R-DDI-629622-5",
    "displayName" : "STAT1 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 170941,
    "identifier" : "Q54WB7",
    "standardIdentifier" : "uniprot:Q54WB7",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 11008994 ],
    "children" : [ ]
  }, {
    "dbId" : 11008986,
    "stId" : "R-DDI-629622-4",
    "displayName" : "STAT1 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 170941,
    "identifier" : "Q54GL9",
    "standardIdentifier" : "uniprot:Q54GL9",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 11008994 ],
    "children" : [ ]
  }, {
    "dbId" : 11008984,
    "stId" : "R-DDI-629622-3",
    "displayName" : "dstC [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 170941,
    "identifier" : "Q54BD4",
    "standardIdentifier" : "uniprot:Q54BD4",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "dstC" ],
    "parents" : [ 11008994 ],
    "children" : [ ]
  }, {
    "dbId" : 11013929,
    "stId" : "R-DDI-936552-2",
    "displayName" : "ISG15 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 170941,
    "identifier" : "Q54SI8",
    "standardIdentifier" : "uniprot:Q54SI8",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 11013933 ],
    "children" : [ ]
  }, {
    "dbId" : 11013931,
    "stId" : "R-DDI-936552-3",
    "displayName" : "nedd8l1 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 170941,
    "identifier" : "Q54TK0",
    "standardIdentifier" : "uniprot:Q54TK0",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "nedd8l1" ],
    "parents" : [ 11013933 ],
    "children" : [ ]
  }, {
    "dbId" : 11013933,
    "stId" : "R-DDI-936552-4",
    "displayName" : "Homologues of ISG15 [cytosol]",
    "schemaClass" : "DefinedSet",
    "speciesId" : 170941,
    "parents" : [ 11015710 ],
    "children" : [ 11013927, 11013931, 11013929 ]
  }, {
    "dbId" : 11050030,
    "stId" : "R-DDI-2559580",
    "displayName" : "Oxidative Stress Induced Senescence",
    "schemaClass" : "Pathway",
    "speciesId" : 170941,
    "diagramIds" : [ 151217 ]
  }, {
    "dbId" : 11013935,
    "stId" : "R-DDI-936014",
    "displayName" : "UBE2L6 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 170941,
    "identifier" : "Q54FX4",
    "standardIdentifier" : "uniprot:Q54FX4",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 11013939 ],
    "children" : [ ]
  }, {
    "dbId" : 11015712,
    "stId" : "R-DDI-1678825",
    "displayName" : "ARIH1 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 170941,
    "identifier" : "Q6T486",
    "standardIdentifier" : "uniprot:Q6T486",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 11015714 ],
    "children" : [ ]
  }, {
    "dbId" : 11023393,
    "stId" : "R-DDI-5218716-4",
    "displayName" : "Homologues of p-S225-SPHK1 [cytosol]",
    "schemaClass" : "DefinedSet",
    "speciesId" : 170941,
    "diagramIds" : [ 151171 ],
    "parents" : [ 11047259 ],
    "children" : [ 11023391, 11023388, 11023385 ]
  }, {
    "dbId" : 11015714,
    "stId" : "R-DDI-1169381",
    "displayName" : "ISG15 E3 ligases [cytosol]",
    "schemaClass" : "DefinedSet",
    "speciesId" : 170941,
    "diagramIds" : [ 151142 ],
    "parents" : [ 11015716 ],
    "children" : [ 11013925, 11015712 ]
  }, {
    "dbId" : 11013923,
    "stId" : "R-DDI-936553-5",
    "displayName" : "gacGG [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 170941,
    "identifier" : "Q54VW7",
    "standardIdentifier" : "uniprot:Q54VW7",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "gacGG" ],
    "parents" : [ 11013925 ],
    "children" : [ ]
  }, {
    "dbId" : 11015716,
    "stId" : "R-DDI-1169383",
    "displayName" : "ISG15:UBCH8:ISG15 E3 ligase [cytosol]",
    "schemaClass" : "Complex",
    "speciesId" : 170941,
    "diagramIds" : [ 151140 ],
    "parents" : [ ],
    "children" : [ 11015714, 11015710 ]
  }, {
    "dbId" : 11013925,
    "stId" : "R-DDI-936553-6",
    "displayName" : "Homologues of HERC5 [cytosol]",
    "schemaClass" : "DefinedSet",
    "speciesId" : 170941,
    "parents" : [ 11015714 ],
    "children" : [ 11013908, 11013923, 11013903, 11013918, 11013913 ]
  }, {
    "dbId" : 9833755,
    "stId" : "R-ALL-9833755",
    "displayName" : "short double-stranded RNA with single-stranded tail(s) [cytosol]",
    "schemaClass" : "OtherEntity",
    "speciesId" : 0,
    "parents" : [ 9833766 ],
    "children" : [ ]
  }, {
    "dbId" : 11013927,
    "stId" : "R-DDI-936552",
    "displayName" : "nedd8l2 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 170941,
    "identifier" : "Q54L35",
    "standardIdentifier" : "uniprot:Q54L35",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "nedd8l2" ],
    "parents" : [ 11013933 ],
    "children" : [ ]
  }, {
    "dbId" : 11047224,
    "stId" : "R-DDI-6782261",
    "displayName" : "dus2l [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 170941,
    "diagramIds" : [ 151151 ],
    "identifier" : "Q54QJ2",
    "standardIdentifier" : "uniprot:Q54QJ2",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "dus2l" ],
    "parents" : [ 11047226 ],
    "children" : [ ]
  }, {
    "dbId" : 11015737,
    "stId" : "R-DDI-168699-2",
    "displayName" : "EIF2AK2 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 170941,
    "identifier" : "Q55DK2",
    "standardIdentifier" : "uniprot:Q55DK2",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 11015739 ],
    "children" : [ ]
  }, {
    "dbId" : 11047226,
    "stId" : "R-DDI-9835379",
    "displayName" : "DUS2:EIF2AK2 [cytosol]",
    "schemaClass" : "Complex",
    "speciesId" : 170941,
    "diagramIds" : [ 151152 ],
    "parents" : [ ],
    "children" : [ 11015739, 11047224 ]
  }, {
    "dbId" : 11015739,
    "stId" : "R-DDI-168699-3",
    "displayName" : "Homologues of EIF2AK2 [cytosol]",
    "schemaClass" : "DefinedSet",
    "speciesId" : 170941,
    "diagramIds" : [ 151137 ],
    "parents" : [ 11047293, 11047236, 11047226, 11047259, 11047230, 11047161 ],
    "children" : [ 11015735, 11015737 ]
  }, {
    "dbId" : 11047230,
    "stId" : "R-DDI-9835442",
    "displayName" : "STAT1,STAT3:EIF2AK2 [cytosol]",
    "schemaClass" : "Complex",
    "speciesId" : 170941,
    "diagramIds" : [ 151155 ],
    "parents" : [ ],
    "children" : [ 11042486, 11015739 ]
  }, {
    "dbId" : 11013937,
    "stId" : "R-DDI-936014-2",
    "displayName" : "ubcB [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 170941,
    "identifier" : "Q94490",
    "standardIdentifier" : "uniprot:Q94490",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "ubcB" ],
    "parents" : [ 11013939 ],
    "children" : [ ]
  }, {
    "dbId" : 11047217,
    "stId" : "R-DDI-9835118",
    "displayName" : "EIF2AK2 dimer:heparin [cytosol]",
    "schemaClass" : "Complex",
    "speciesId" : 170941,
    "diagramIds" : [ 151149 ],
    "parents" : [ ],
    "children" : [ 9835132, 11047161 ]
  }, {
    "dbId" : 11013939,
    "stId" : "R-DDI-936014-3",
    "displayName" : "Homologues of UBE2L6 [cytosol]",
    "schemaClass" : "DefinedSet",
    "speciesId" : 170941,
    "diagramIds" : [ 151146 ],
    "parents" : [ 11015710 ],
    "children" : [ 11013937, 11013935 ]
  }, {
    "dbId" : 11015735,
    "stId" : "R-DDI-168699",
    "displayName" : "EIF2AK2 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 170941,
    "identifier" : "Q54R98",
    "standardIdentifier" : "uniprot:Q54R98",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 11015739 ],
    "children" : [ ]
  }, {
    "dbId" : 11047177,
    "stId" : "R-DDI-9833969",
    "displayName" : "ISG15-EIF2AK2 dimer [cytosol]",
    "schemaClass" : "Complex",
    "speciesId" : 170941,
    "diagramIds" : [ 151145 ],
    "parents" : [ ],
    "children" : [ 11047175 ]
  }, {
    "dbId" : 11013903,
    "stId" : "R-DDI-936553",
    "displayName" : "HERC5 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 170941,
    "identifier" : "Q54BC4",
    "standardIdentifier" : "uniprot:Q54BC4",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 11013925 ],
    "children" : [ ]
  }, {
    "dbId" : 11047169,
    "stId" : "R-DDI-9833968",
    "displayName" : "ISG15-EIF2AK2 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 170941,
    "identifier" : "Q54R98",
    "standardIdentifier" : "uniprot:Q54R98",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 11047175 ],
    "children" : [ ]
  }, {
    "dbId" : 11047173,
    "stId" : "R-DDI-9833968-2",
    "displayName" : "ISG15-EIF2AK2 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 170941,
    "identifier" : "Q55DK2",
    "standardIdentifier" : "uniprot:Q55DK2",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 11047175 ],
    "children" : [ ]
  }, {
    "dbId" : 29358,
    "stId" : "R-ALL-29358",
    "displayName" : "ATP [nucleoplasm]",
    "schemaClass" : "SimpleEntity",
    "speciesId" : 0,
    "diagramIds" : [ 151174 ],
    "identifier" : "30616",
    "standardIdentifier" : "chebi:30616",
    "referenceType" : "ReferenceMolecule",
    "parents" : [ ],
    "children" : [ ]
  }, {
    "dbId" : 11047175,
    "stId" : "R-DDI-9833968-3",
    "displayName" : "Homologues of ISG15-EIF2AK2 [cytosol]",
    "schemaClass" : "DefinedSet",
    "speciesId" : 170941,
    "parents" : [ 11047177 ],
    "children" : [ 11047173, 11047169 ]
  }, {
    "dbId" : 113582,
    "stId" : "R-ALL-113582",
    "displayName" : "ADP [nucleoplasm]",
    "schemaClass" : "SimpleEntity",
    "speciesId" : 0,
    "diagramIds" : [ 151177 ],
    "identifier" : "456216",
    "standardIdentifier" : "chebi:456216",
    "referenceType" : "ReferenceMolecule",
    "parents" : [ ],
    "children" : [ ]
  }, {
    "dbId" : 9833766,
    "stId" : "R-HSA-9833766",
    "displayName" : "Host RNA activators of PKR [cytosol]",
    "schemaClass" : "DefinedSet",
    "speciesId" : 48887,
    "diagramIds" : [ 151136 ],
    "parents" : [ 11047163 ],
    "children" : [ 9833832, 9833755, 9833770, 9833774, 170292, 9833830 ]
  }, {
    "dbId" : 11013913,
    "stId" : "R-DDI-936553-3",
    "displayName" : "tirA [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 170941,
    "identifier" : "Q54HT1",
    "standardIdentifier" : "uniprot:Q54HT1",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "tirA" ],
    "parents" : [ 11013925 ],
    "children" : [ ]
  }, {
    "dbId" : 11023385,
    "stId" : "R-DDI-5218716",
    "displayName" : "phospho-p-S225-SPHK1 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 170941,
    "identifier" : "Q6B516",
    "standardIdentifier" : "uniprot:Q6B516",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 11023393 ],
    "children" : [ ]
  }, {
    "dbId" : 11023388,
    "stId" : "R-DDI-5218716-2",
    "displayName" : "phospho-sgkC [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 170941,
    "identifier" : "Q75JX1",
    "standardIdentifier" : "uniprot:Q75JX1",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "sgkC" ],
    "parents" : [ 11023393 ],
    "children" : [ ]
  }, {
    "dbId" : 11015710,
    "stId" : "R-DDI-1169385",
    "displayName" : "ISG15:UBCH8 [cytosol]",
    "schemaClass" : "Complex",
    "speciesId" : 170941,
    "parents" : [ 11015716 ],
    "children" : [ 11013939, 11013933 ]
  }, {
    "dbId" : 11013918,
    "stId" : "R-DDI-936553-4",
    "displayName" : "HERC5 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 170941,
    "identifier" : "Q54NH2",
    "standardIdentifier" : "uniprot:Q54NH2",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 11013925 ],
    "children" : [ ]
  }, {
    "dbId" : 11023391,
    "stId" : "R-DDI-5218716-3",
    "displayName" : "phospho-p-S225-SPHK1 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 170941,
    "identifier" : "Q86KF9",
    "standardIdentifier" : "uniprot:Q86KF9",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 11023393 ],
    "children" : [ ]
  }, {
    "dbId" : 9833774,
    "stId" : "R-ALL-9833774",
    "displayName" : "circular RNA [cytosol]",
    "schemaClass" : "OtherEntity",
    "speciesId" : 0,
    "parents" : [ 9833766 ],
    "children" : [ ]
  }, {
    "dbId" : 113592,
    "stId" : "R-ALL-113592",
    "displayName" : "ATP [cytosol]",
    "schemaClass" : "SimpleEntity",
    "speciesId" : 0,
    "diagramIds" : [ 151141, 151160, 151165, 151181 ],
    "identifier" : "30616",
    "standardIdentifier" : "chebi:30616",
    "referenceType" : "ReferenceMolecule",
    "parents" : [ ],
    "children" : [ ]
  }, {
    "dbId" : 29370,
    "stId" : "R-ALL-29370",
    "displayName" : "ADP [cytosol]",
    "schemaClass" : "SimpleEntity",
    "speciesId" : 0,
    "diagramIds" : [ 151168, 151163, 151183 ],
    "identifier" : "456216",
    "standardIdentifier" : "chebi:456216",
    "referenceType" : "ReferenceMolecule",
    "parents" : [ ],
    "children" : [ ]
  }, {
    "dbId" : 11013908,
    "stId" : "R-DDI-936553-2",
    "displayName" : "HERC5 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 170941,
    "identifier" : "Q54D12",
    "standardIdentifier" : "uniprot:Q54D12",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 11013925 ],
    "children" : [ ]
  }, {
    "dbId" : 9833770,
    "stId" : "R-ALL-9833770",
    "displayName" : "unprocessed misfolded tRNA [cytosol]",
    "schemaClass" : "OtherEntity",
    "speciesId" : 0,
    "parents" : [ 9833766 ],
    "children" : [ ]
  }, {
    "dbId" : 111294,
    "stId" : "R-ALL-111294",
    "displayName" : "PPi [cytosol]",
    "schemaClass" : "SimpleEntity",
    "speciesId" : 0,
    "diagramIds" : [ 151144 ],
    "identifier" : "33019",
    "standardIdentifier" : "chebi:33019",
    "chebiIdentifier" : "chebi:33019",
    "referenceType" : "ReferenceMolecule",
    "parents" : [ ],
    "children" : [ ]
  }, {
    "dbId" : 11047273,
    "stId" : "R-DDI-9836613-2",
    "displayName" : "phospho-sgkC [nucleoplasm]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 170941,
    "identifier" : "Q75JX1",
    "standardIdentifier" : "uniprot:Q75JX1",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "sgkC" ],
    "parents" : [ 11047277 ],
    "children" : [ ]
  }, {
    "dbId" : 11008869,
    "stId" : "R-DDI-191689",
    "displayName" : "TUBA1A [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 170941,
    "identifier" : "P32255",
    "standardIdentifier" : "uniprot:P32255",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 11008876 ],
    "children" : [ ]
  }, {
    "dbId" : 11047275,
    "stId" : "R-DDI-9836613-3",
    "displayName" : "phospho-p-S225-SPHK1 [nucleoplasm]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 170941,
    "identifier" : "Q86KF9",
    "standardIdentifier" : "uniprot:Q86KF9",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 11047277 ],
    "children" : [ ]
  }, {
    "dbId" : 11047277,
    "stId" : "R-DDI-9836613-4",
    "displayName" : "Homologues of p-S225-SPHK1 [nucleoplasm]",
    "schemaClass" : "DefinedSet",
    "speciesId" : 170941,
    "diagramIds" : [ 151176 ],
    "parents" : [ ],
    "children" : [ 11047271, 11047275, 11047273 ]
  }, {
    "dbId" : 11008878,
    "stId" : "R-DDI-190590",
    "displayName" : "TUBA1C [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 170941,
    "identifier" : "P32255",
    "standardIdentifier" : "uniprot:P32255",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 11008882 ],
    "children" : [ ]
  }, {
    "dbId" : 11047265,
    "stId" : "R-DDI-9836616-2",
    "displayName" : "sgkC [nucleoplasm]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 170941,
    "identifier" : "Q75JX1",
    "standardIdentifier" : "uniprot:Q75JX1",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "sgkC" ],
    "parents" : [ 11047269 ],
    "children" : [ ]
  }, {
    "dbId" : 11008876,
    "stId" : "R-DDI-191689-3",
    "displayName" : "Homologues of TUBA1A [cytosol]",
    "schemaClass" : "DefinedSet",
    "speciesId" : 170941,
    "parents" : [ 11008896 ],
    "children" : [ 11008874, 11008869 ]
  }, {
    "dbId" : 9669720,
    "stId" : "R-ALL-9669720",
    "displayName" : "sunitinib [cytosol]",
    "schemaClass" : "ChemicalDrug",
    "speciesId" : 0,
    "identifier" : "5713",
    "standardIdentifier" : "iuphar.ligand:5713",
    "chebiIdentifier" : "chebi:91430",
    "parents" : [ 9836704 ],
    "children" : [ ]
  }, {
    "dbId" : 11047267,
    "stId" : "R-DDI-9836616-3",
    "displayName" : "SPHK1 [nucleoplasm]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 170941,
    "identifier" : "Q86KF9",
    "standardIdentifier" : "uniprot:Q86KF9",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 11047269 ],
    "children" : [ ]
  }, {
    "dbId" : 11008874,
    "stId" : "R-DDI-191689-2",
    "displayName" : "TUBA1A [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 170941,
    "identifier" : "Q54TA6",
    "standardIdentifier" : "uniprot:Q54TA6",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 11008876 ],
    "children" : [ ]
  }, {
    "dbId" : 11047269,
    "stId" : "R-DDI-9836616-4",
    "displayName" : "Homologues of SPHK1 [nucleoplasm]",
    "schemaClass" : "DefinedSet",
    "speciesId" : 170941,
    "diagramIds" : [ 151175 ],
    "parents" : [ ],
    "children" : [ 11047267, 11047265, 11047263 ]
  }, {
    "dbId" : 11047271,
    "stId" : "R-DDI-9836613",
    "displayName" : "phospho-p-S225-SPHK1 [nucleoplasm]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 170941,
    "identifier" : "Q6B516",
    "standardIdentifier" : "uniprot:Q6B516",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 11047277 ],
    "children" : [ ]
  }, {
    "dbId" : 11008886,
    "stId" : "R-DDI-6805233",
    "displayName" : "TUBA3E [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 170941,
    "identifier" : "P32255",
    "standardIdentifier" : "uniprot:P32255",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 11008888 ],
    "children" : [ ]
  }, {
    "dbId" : 11047289,
    "stId" : "R-DDI-9836662",
    "displayName" : "Activated PPP2R5A-specific PP2A [cytosol]",
    "schemaClass" : "Complex",
    "speciesId" : 170941,
    "diagramIds" : [ 151182 ],
    "parents" : [ ],
    "children" : [ 11047287, 11009484, 11009488 ]
  }, {
    "dbId" : 11008884,
    "stId" : "R-DDI-9617120",
    "displayName" : "TUBA3C [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 170941,
    "identifier" : "Q54TA6",
    "standardIdentifier" : "uniprot:Q54TA6",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 11008896, 11008888 ],
    "children" : [ ]
  }, {
    "dbId" : 11008882,
    "stId" : "R-DDI-190590-3",
    "displayName" : "Homologues of TUBA1C [cytosol]",
    "schemaClass" : "DefinedSet",
    "speciesId" : 170941,
    "parents" : [ 11008896 ],
    "children" : [ 11008878, 11008880 ]
  }, {
    "dbId" : 11047293,
    "stId" : "R-DDI-9836700",
    "displayName" : "EIF2AK2:PKR inhibitors [cytosol]",
    "schemaClass" : "Complex",
    "speciesId" : 170941,
    "diagramIds" : [ 151186 ],
    "parents" : [ ],
    "children" : [ 9836704, 11015739 ]
  }, {
    "dbId" : 11012222,
    "stId" : "R-DDI-206255",
    "displayName" : "phospho-p-S207,T211-MAP2K6 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 170941,
    "diagramIds" : [ 151162 ],
    "identifier" : "Q54HS0",
    "standardIdentifier" : "uniprot:Q54HS0",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ ],
    "children" : [ ]
  }, {
    "dbId" : 11008880,
    "stId" : "R-DDI-190590-2",
    "displayName" : "TUBA1C [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 170941,
    "identifier" : "Q54TA6",
    "standardIdentifier" : "uniprot:Q54TA6",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 11008882 ],
    "children" : [ ]
  }, {
    "dbId" : 11008894,
    "stId" : "R-DDI-191694-3",
    "displayName" : "Homologues of TUBA4A [cytosol]",
    "schemaClass" : "DefinedSet",
    "speciesId" : 170941,
    "parents" : [ 11008896 ],
    "children" : [ 11008890, 11008892 ]
  }, {
    "dbId" : 11008892,
    "stId" : "R-DDI-191694-2",
    "displayName" : "TUBA4A [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 170941,
    "identifier" : "Q54TA6",
    "standardIdentifier" : "uniprot:Q54TA6",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 11008894 ],
    "children" : [ ]
  }, {
    "dbId" : 11047284,
    "stId" : "R-DDI-9836650",
    "displayName" : "PPP2R5A-specific PP2A [cytosol]",
    "schemaClass" : "Complex",
    "speciesId" : 170941,
    "diagramIds" : [ 151180 ],
    "parents" : [ ],
    "children" : [ 11009484, 11009468, 11009488 ]
  }, {
    "dbId" : 11008890,
    "stId" : "R-DDI-191694",
    "displayName" : "TUBA4A [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 170941,
    "identifier" : "P32255",
    "standardIdentifier" : "uniprot:P32255",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 11008894 ],
    "children" : [ ]
  }, {
    "dbId" : 11008888,
    "stId" : "R-DDI-6805233-2",
    "displayName" : "Homologues of TUBA3E [cytosol]",
    "schemaClass" : "DefinedSet",
    "speciesId" : 170941,
    "parents" : [ 11008896 ],
    "children" : [ 11008884, 11008886 ]
  }, {
    "dbId" : 11047287,
    "stId" : "R-DDI-9836658",
    "displayName" : "phospho-psrA [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 170941,
    "identifier" : "Q54VB6",
    "standardIdentifier" : "uniprot:Q54VB6",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "psrA" ],
    "parents" : [ 11047289 ],
    "children" : [ ]
  }, {
    "dbId" : 11047243,
    "stId" : "R-DDI-9619519",
    "displayName" : "MAPT-8 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 170941,
    "identifier" : "Q54H52",
    "standardIdentifier" : "uniprot:Q54H52",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 11047245 ],
    "children" : [ ]
  }, {
    "dbId" : 11047245,
    "stId" : "R-DDI-9619556",
    "displayName" : "MAPT-8:Microtubule [cytosol]",
    "schemaClass" : "Complex",
    "speciesId" : 170941,
    "diagramIds" : [ 151166 ],
    "parents" : [ ],
    "children" : [ 11008921, 11047243 ]
  }, {
    "dbId" : 11047234,
    "stId" : "R-DDI-448199",
    "displayName" : "dnajc3 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 170941,
    "diagramIds" : [ 151157 ],
    "identifier" : "Q54M21",
    "standardIdentifier" : "uniprot:Q54M21",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "dnajc3" ],
    "parents" : [ 11047236 ],
    "children" : [ ]
  }, {
    "dbId" : 9835132,
    "stId" : "R-ALL-9835132",
    "displayName" : "heparin [cytosol]",
    "schemaClass" : "ChemicalDrug",
    "speciesId" : 0,
    "diagramIds" : [ 151148 ],
    "identifier" : "4214",
    "standardIdentifier" : "iuphar.ligand:4214",
    "chebiIdentifier" : "chebi:28304",
    "parents" : [ 11047217 ],
    "children" : [ ]
  }, {
    "dbId" : 11047236,
    "stId" : "R-DDI-9835465",
    "displayName" : "DNAJC3:EIF2AK2 [cytosol]",
    "schemaClass" : "Complex",
    "speciesId" : 170941,
    "diagramIds" : [ 151158 ],
    "parents" : [ ],
    "children" : [ 11047234, 11015739 ]
  }, {
    "dbId" : 29420,
    "stId" : "R-ALL-29420",
    "displayName" : "GDP [cytosol]",
    "schemaClass" : "SimpleEntity",
    "speciesId" : 0,
    "identifier" : "58189",
    "standardIdentifier" : "chebi:58189",
    "referenceType" : "ReferenceMolecule",
    "parents" : [ 11008915 ],
    "children" : [ ]
  }, {
    "dbId" : 9833830,
    "stId" : "R-ALL-9833830",
    "displayName" : "dsRNA duplex [cytosol]",
    "schemaClass" : "OtherEntity",
    "speciesId" : 0,
    "parents" : [ 9833766 ],
    "children" : [ ]
  }, {
    "dbId" : 11047259,
    "stId" : "R-DDI-9836608",
    "displayName" : "EIF2AK2:p-SPHK1 [cytosol]",
    "schemaClass" : "Complex",
    "speciesId" : 170941,
    "diagramIds" : [ 151172 ],
    "parents" : [ ],
    "children" : [ 11023393, 11015739 ]
  }, {
    "dbId" : 11047263,
    "stId" : "R-DDI-9836616",
    "displayName" : "SPHK1 [nucleoplasm]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 170941,
    "identifier" : "Q6B516",
    "standardIdentifier" : "uniprot:Q6B516",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 11047269 ],
    "children" : [ ]
  }, {
    "dbId" : 11049042,
    "stId" : "R-DDI-72613",
    "displayName" : "Eukaryotic Translation Initiation",
    "schemaClass" : "Pathway",
    "speciesId" : 170941,
    "diagramIds" : [ 151215 ]
  }, {
    "dbId" : 29438,
    "stId" : "R-ALL-29438",
    "displayName" : "GTP [cytosol]",
    "schemaClass" : "SimpleEntity",
    "speciesId" : 0,
    "identifier" : "37565",
    "standardIdentifier" : "chebi:37565",
    "referenceType" : "ReferenceMolecule",
    "parents" : [ 11008898 ],
    "children" : [ ]
  }, {
    "dbId" : 9833832,
    "stId" : "R-ALL-9833832",
    "displayName" : "snoRNA [cytosol]",
    "schemaClass" : "OtherEntity",
    "speciesId" : 0,
    "parents" : [ 9833766 ],
    "children" : [ ]
  }, {
    "dbId" : 11047255,
    "stId" : "R-DDI-9836400",
    "displayName" : "phospho-p-S199,S202,S262,S396,S404,S409,T181,T231-MAPT-8 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 170941,
    "diagramIds" : [ 151167 ],
    "identifier" : "Q54H52",
    "standardIdentifier" : "uniprot:Q54H52",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ ],
    "children" : [ ]
  } ],
  "edges" : [ {
    "dbId" : 11047241,
    "stId" : "R-DDI-9836322",
    "displayName" : "p-PKR dimer phosphorylates MKK6",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "inputs" : [ 113592, 11012264 ],
    "outputs" : [ 29370, 11012222 ],
    "catalysts" : [ 11047149 ],
    "efs" : [ ],
    "diagramIds" : [ 151159 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 11047179,
    "stId" : "R-DDI-9833973",
    "displayName" : "ISGylation of PKR",
    "schemaClass" : "BlackBoxEvent",
    "speciesId" : 0,
    "inputs" : [ 11015716, 113592, 11015739 ],
    "outputs" : [ 111294, 11013939, 11015714, 11047177, 76577 ],
    "catalysts" : [ 11015716 ],
    "efs" : [ ],
    "diagramIds" : [ 151139 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 11047232,
    "stId" : "R-DDI-9835443",
    "displayName" : "STAT1,STAT3 binds PKR",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "inputs" : [ 11042486, 11015739 ],
    "outputs" : [ 11047230 ],
    "efs" : [ ],
    "diagramIds" : [ 151153 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 11047238,
    "stId" : "R-DDI-9835454",
    "displayName" : "DNAJC3 binds PKR",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "inputs" : [ 11047234, 11015739 ],
    "outputs" : [ 11047236 ],
    "efs" : [ ],
    "diagramIds" : [ 151156 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 11047257,
    "stId" : "R-DDI-9836404",
    "displayName" : "p-PKR dimer phosphorylates MAPT",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "inputs" : [ 113592, 11047245 ],
    "outputs" : [ 11047255, 11008921, 29370 ],
    "catalysts" : [ 11047149 ],
    "efs" : [ ],
    "diagramIds" : [ 151164 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 11047291,
    "stId" : "R-DDI-9836664",
    "displayName" : "p-PKR dimer phosphorylates PPP2R5A",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "inputs" : [ 11047284, 113592 ],
    "outputs" : [ 29370, 11047289 ],
    "catalysts" : [ 11047149 ],
    "efs" : [ ],
    "diagramIds" : [ 151179 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 11047228,
    "stId" : "R-DDI-9835385",
    "displayName" : "DUS2 binds PKR",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "inputs" : [ 11015739, 11047224 ],
    "outputs" : [ 11047226 ],
    "efs" : [ ],
    "diagramIds" : [ 151150 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 11047165,
    "stId" : "R-DDI-9833777",
    "displayName" : "PKR binds activating host RNA",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "inputs" : [ 11015739, 9833766 ],
    "outputs" : [ 11047163 ],
    "efs" : [ ],
    "diagramIds" : [ 151135 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 11047261,
    "stId" : "R-DDI-9836606",
    "displayName" : "SPHK1 binds PKR",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "inputs" : [ 11023393, 11015739 ],
    "outputs" : [ 11047259 ],
    "efs" : [ ],
    "diagramIds" : [ 151170 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 11047295,
    "stId" : "R-DDI-9836702",
    "displayName" : "PKR inhibitors bind PKR",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "inputs" : [ 9836704, 11015739 ],
    "outputs" : [ 11047293 ],
    "efs" : [ ],
    "diagramIds" : [ 151184 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 11047280,
    "stId" : "R-DDI-9836617",
    "displayName" : "p-PKR dimer phosphorylates SPHK1",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "preceding" : [ 11047159 ],
    "following" : [ 11047282 ],
    "inputs" : [ 29358, 11047269 ],
    "outputs" : [ 113582, 11047277 ],
    "catalysts" : [ 11047157 ],
    "efs" : [ ],
    "diagramIds" : [ 151173 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 11047282,
    "stId" : "R-DDI-9836621",
    "displayName" : "p-S225-SPHK1 localizes to cytosol",
    "schemaClass" : "BlackBoxEvent",
    "speciesId" : 0,
    "preceding" : [ 11047280 ],
    "inputs" : [ 11047277 ],
    "outputs" : [ 11023393 ],
    "efs" : [ ],
    "diagramIds" : [ 151178 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 11047219,
    "stId" : "R-DDI-9835121",
    "displayName" : "Heparin binds PKR",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "inputs" : [ 9835132, 11015739 ],
    "outputs" : [ 11047217 ],
    "efs" : [ ],
    "diagramIds" : [ 151147 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 11047159,
    "stId" : "R-DDI-9833635",
    "displayName" : "p-PKR dimer localizes to the nucleus",
    "schemaClass" : "BlackBoxEvent",
    "speciesId" : 0,
    "following" : [ 11047280 ],
    "inputs" : [ 11047149 ],
    "outputs" : [ 11047157 ],
    "efs" : [ ],
    "diagramIds" : [ 151132 ],
    "entityFunctionalStatus" : [ ]
  } ]
}