{
  "dbId" : 11050628,
  "stId" : "R-DDI-5633008",
  "speciesName" : "Dictyostelium discoideum",
  "nodes" : [ {
    "dbId" : 11034984,
    "stId" : "R-DDI-6801105",
    "displayName" : "RGGT [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 170941,
    "diagramIds" : [ 83079 ],
    "parents" : [ 11034993 ],
    "children" : [ 11034982, 11034977 ]
  }, {
    "dbId" : 11050606,
    "stId" : "R-DDI-5633007",
    "displayName" : "Regulation of TP53 Activity",
    "schemaClass" : "Pathway",
    "speciesId" : 170941,
    "diagramIds" : [ 83096 ]
  }, {
    "dbId" : 11034991,
    "stId" : "R-DDI-6801097",
    "displayName" : "CHM [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 170941,
    "diagramIds" : [ 83081 ],
    "identifier" : "Q54VT9",
    "standardIdentifier" : "uniprot:Q54VT9",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 11034993 ],
    "children" : [ ]
  }, {
    "dbId" : 11034977,
    "stId" : "R-DDI-6801086",
    "displayName" : "rabggta [plasma membrane]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 170941,
    "diagramIds" : [ 83077 ],
    "identifier" : "Q55DQ4",
    "standardIdentifier" : "uniprot:Q55DQ4",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "rabggta" ],
    "parents" : [ 11034984 ],
    "children" : [ ]
  }, {
    "dbId" : 6799726,
    "stId" : "R-ALL-6799726",
    "displayName" : "semiquinone [cytosol]",
    "schemaClass" : "SimpleEntity",
    "speciesId" : 0,
    "diagramIds" : [ 83067 ],
    "identifier" : "15817",
    "standardIdentifier" : "chebi:15817",
    "referenceType" : "ReferenceMolecule",
    "parents" : [ ],
    "children" : [ ]
  }, {
    "dbId" : 6799725,
    "stId" : "R-ALL-6799725",
    "displayName" : "1,2-Naphthoquinone [cytosol]",
    "schemaClass" : "SimpleEntity",
    "speciesId" : 0,
    "diagramIds" : [ 83064 ],
    "identifier" : "34055",
    "standardIdentifier" : "chebi:34055",
    "referenceType" : "ReferenceMolecule",
    "parents" : [ ],
    "children" : [ ]
  }, {
    "dbId" : 11034982,
    "stId" : "R-DDI-6801098",
    "displayName" : "RABGGTB [plasma membrane]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 170941,
    "diagramIds" : [ 83078 ],
    "identifier" : "B0G172",
    "standardIdentifier" : "uniprot:B0G172",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 11034984 ],
    "children" : [ ]
  }, {
    "dbId" : 11035000,
    "stId" : "R-DDI-1307778",
    "displayName" : "TRIAP1 [mitochondrial intermembrane space]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 170941,
    "diagramIds" : [ 83085 ],
    "identifier" : "Q54KL1",
    "standardIdentifier" : "uniprot:Q54KL1",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 11035009 ],
    "children" : [ ]
  }, {
    "dbId" : 1524101,
    "stId" : "R-ALL-1524101",
    "displayName" : "PA [mitochondrial inner membrane]",
    "schemaClass" : "SimpleEntity",
    "speciesId" : 0,
    "diagramIds" : [ 83089 ],
    "identifier" : "57739",
    "standardIdentifier" : "chebi:57739",
    "referenceType" : "ReferenceMolecule",
    "parents" : [ ],
    "children" : [ ]
  }, {
    "dbId" : 11035005,
    "stId" : "R-DDI-6801215",
    "displayName" : "slmo [mitochondrial intermembrane space]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 170941,
    "diagramIds" : [ 83084 ],
    "identifier" : "Q54G07",
    "standardIdentifier" : "uniprot:Q54G07",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "slmo" ],
    "parents" : [ 11035009 ],
    "children" : [ ]
  }, {
    "dbId" : 11049470,
    "stId" : "R-DDI-168249",
    "displayName" : "Innate Immune System",
    "schemaClass" : "Pathway",
    "speciesId" : 170941,
    "diagramIds" : [ 83101 ]
  }, {
    "dbId" : 11034993,
    "stId" : "R-DDI-6801111",
    "displayName" : "RGGT:CHM [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 170941,
    "diagramIds" : [ 83082 ],
    "parents" : [ ],
    "children" : [ 11034991, 11034984 ]
  }, {
    "dbId" : 70106,
    "stId" : "R-ALL-70106",
    "displayName" : "H+ [cytosol]",
    "schemaClass" : "SimpleEntity",
    "speciesId" : 0,
    "diagramIds" : [ 83063 ],
    "identifier" : "15378",
    "standardIdentifier" : "chebi:15378",
    "referenceType" : "ReferenceMolecule",
    "parents" : [ ],
    "children" : [ ]
  }, {
    "dbId" : 11049354,
    "stId" : "R-DDI-109606",
    "displayName" : "Intrinsic Pathway for Apoptosis",
    "schemaClass" : "Pathway",
    "speciesId" : 170941,
    "diagramIds" : [ 83092 ]
  }, {
    "dbId" : 11034956,
    "stId" : "R-DDI-6800483",
    "displayName" : "lrrA [nucleoplasm]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 170941,
    "diagramIds" : [ 83069 ],
    "identifier" : "Q54AX5",
    "standardIdentifier" : "uniprot:Q54AX5",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "lrrA" ],
    "parents" : [ ],
    "children" : [ ]
  }, {
    "dbId" : 11034959,
    "stId" : "R-DDI-6800485",
    "displayName" : "phospho-lrrA [nucleoplasm]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 170941,
    "diagramIds" : [ 83071 ],
    "identifier" : "Q54AX5",
    "standardIdentifier" : "uniprot:Q54AX5",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "lrrA" ],
    "parents" : [ ],
    "children" : [ ]
  }, {
    "dbId" : 11035009,
    "stId" : "R-DDI-6801235",
    "displayName" : "TRIAP1:PRELID1, PRELID3A [mitochondrial intermembrane space]",
    "schemaClass" : "Complex",
    "speciesId" : 170941,
    "diagramIds" : [ 83086 ],
    "parents" : [ ],
    "children" : [ 11035005, 11035000 ]
  }, {
    "dbId" : 29358,
    "stId" : "R-ALL-29358",
    "displayName" : "ATP [nucleoplasm]",
    "schemaClass" : "SimpleEntity",
    "speciesId" : 0,
    "diagramIds" : [ 83070 ],
    "identifier" : "30616",
    "standardIdentifier" : "chebi:30616",
    "referenceType" : "ReferenceMolecule",
    "parents" : [ ],
    "children" : [ ]
  }, {
    "dbId" : 113582,
    "stId" : "R-ALL-113582",
    "displayName" : "ADP [nucleoplasm]",
    "schemaClass" : "SimpleEntity",
    "speciesId" : 0,
    "diagramIds" : [ 83072 ],
    "identifier" : "456216",
    "standardIdentifier" : "chebi:456216",
    "referenceType" : "ReferenceMolecule",
    "parents" : [ ],
    "children" : [ ]
  }, {
    "dbId" : 11049816,
    "stId" : "R-DDI-75153",
    "displayName" : "Apoptotic execution phase",
    "schemaClass" : "Pathway",
    "speciesId" : 170941,
    "diagramIds" : [ 83095 ]
  }, {
    "dbId" : 11034459,
    "stId" : "R-DDI-6799460",
    "displayName" : "TP53I3 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 170941,
    "diagramIds" : [ 83060 ],
    "identifier" : "Q75JT6",
    "standardIdentifier" : "uniprot:Q75JT6",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 11034461 ],
    "children" : [ ]
  }, {
    "dbId" : 11008211,
    "stId" : "R-DDI-5693527",
    "displayName" : "phospho-atr1 [nucleoplasm]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 170941,
    "diagramIds" : [ 83073 ],
    "identifier" : "Q54ER4",
    "standardIdentifier" : "uniprot:Q54ER4",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "atr1" ],
    "parents" : [ ],
    "children" : [ ]
  }, {
    "dbId" : 29364,
    "stId" : "R-ALL-29364",
    "displayName" : "NADPH [cytosol]",
    "schemaClass" : "SimpleEntity",
    "speciesId" : 0,
    "diagramIds" : [ 83065 ],
    "identifier" : "57783",
    "standardIdentifier" : "chebi:57783",
    "referenceType" : "ReferenceMolecule",
    "parents" : [ ],
    "children" : [ ]
  }, {
    "dbId" : 11034461,
    "stId" : "R-DDI-6799448",
    "displayName" : "TP53I3 Dimer [cytosol]",
    "schemaClass" : "Complex",
    "speciesId" : 170941,
    "diagramIds" : [ 83061 ],
    "parents" : [ ],
    "children" : [ 11034459 ]
  }, {
    "dbId" : 29366,
    "stId" : "R-ALL-29366",
    "displayName" : "NADP+ [cytosol]",
    "schemaClass" : "SimpleEntity",
    "speciesId" : 0,
    "diagramIds" : [ 83066 ],
    "identifier" : "58349",
    "standardIdentifier" : "chebi:58349",
    "referenceType" : "ReferenceMolecule",
    "parents" : [ ],
    "children" : [ ]
  }, {
    "dbId" : 11050000,
    "stId" : "R-DDI-917937",
    "displayName" : "Iron uptake and transport",
    "schemaClass" : "Pathway",
    "speciesId" : 170941,
    "diagramIds" : [ 83100 ]
  }, {
    "dbId" : 1500590,
    "stId" : "R-ALL-1500590",
    "displayName" : "PA [mitochondrial outer membrane]",
    "schemaClass" : "SimpleEntity",
    "speciesId" : 0,
    "diagramIds" : [ 83088 ],
    "identifier" : "57739",
    "standardIdentifier" : "chebi:57739",
    "referenceType" : "ReferenceMolecule",
    "parents" : [ ],
    "children" : [ ]
  }, {
    "dbId" : 11034963,
    "stId" : "R-DDI-6800271",
    "displayName" : "phospho-lrrA [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 170941,
    "diagramIds" : [ 83075 ],
    "identifier" : "Q54AX5",
    "standardIdentifier" : "uniprot:Q54AX5",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "lrrA" ],
    "parents" : [ ],
    "children" : [ ]
  } ],
  "edges" : [ {
    "dbId" : 11034986,
    "stId" : "R-DDI-6801101",
    "displayName" : "RABGGTA binds RABGGTB",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "following" : [ 11034995 ],
    "inputs" : [ 11034982, 11034977 ],
    "outputs" : [ 11034984 ],
    "efs" : [ ],
    "diagramIds" : [ 83076 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 11034526,
    "stId" : "R-DDI-6799722",
    "displayName" : "TP53I3 oxidoreductase generates unstable semiquinones",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "preceding" : [ 11034463 ],
    "inputs" : [ 70106, 6799725, 29364 ],
    "outputs" : [ 6799726, 29366 ],
    "catalysts" : [ 11034461 ],
    "efs" : [ ],
    "diagramIds" : [ 83062 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 11034463,
    "stId" : "R-DDI-6799466",
    "displayName" : "TP53I3 dimerizes",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "following" : [ 11034526 ],
    "inputs" : [ 11034459 ],
    "outputs" : [ 11034461 ],
    "efs" : [ ],
    "diagramIds" : [ 83059 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 11034961,
    "stId" : "R-DDI-6800490",
    "displayName" : "ATM phosphorylates PIDD1",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "following" : [ 11034965 ],
    "inputs" : [ 29358, 11034956 ],
    "outputs" : [ 113582, 11034959 ],
    "catalysts" : [ 11008211 ],
    "efs" : [ ],
    "diagramIds" : [ 83068 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 11035011,
    "stId" : "R-DDI-6801242",
    "displayName" : "TRIAP1 binds PRELID1, PRELID3A",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "following" : [ 11035014 ],
    "inputs" : [ 11035005, 11035000 ],
    "outputs" : [ 11035009 ],
    "efs" : [ ],
    "diagramIds" : [ 83083 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 11034995,
    "stId" : "R-DDI-6801109",
    "displayName" : "CHM binds RGGT",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "preceding" : [ 11034986 ],
    "inputs" : [ 11034991, 11034984 ],
    "outputs" : [ 11034993 ],
    "efs" : [ ],
    "diagramIds" : [ 83080 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 11034965,
    "stId" : "R-DDI-6800793",
    "displayName" : "PIDD1 translocates to the cytosol",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "preceding" : [ 11034961 ],
    "inputs" : [ 11034959 ],
    "outputs" : [ 11034963 ],
    "efs" : [ ],
    "diagramIds" : [ 83074 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 11035014,
    "stId" : "R-DDI-6801250",
    "displayName" : "TRIAP1:PRELID1, PRELID3A transports PA from the outer to the inner mitochondrial membrane",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "preceding" : [ 11035011 ],
    "inputs" : [ 1500590 ],
    "outputs" : [ 1524101 ],
    "catalysts" : [ 11035009 ],
    "efs" : [ ],
    "diagramIds" : [ 83087 ],
    "entityFunctionalStatus" : [ ]
  } ],
  "subpathways" : [ {
    "dbId" : 11050634,
    "stId" : "R-DDI-6803204",
    "displayName" : "TP53 Regulates Transcription of Genes Involved in Cytochrome C Release",
    "events" : [ 11035011, 11035014 ]
  }, {
    "dbId" : 11050632,
    "stId" : "R-DDI-6803207",
    "displayName" : "TP53 Regulates Transcription of Caspase Activators and Caspases",
    "events" : [ 11034961, 11034965 ]
  }, {
    "dbId" : 11050626,
    "stId" : "R-DDI-6803205",
    "displayName" : "TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain",
    "events" : [ 11034986, 11034526, 11034463, 11034995 ]
  } ]
}