{
  "dbId" : 11049842,
  "stableId" : "R-DDI-9958863",
  "displayName" : "SLC-mediated transport of amino acids",
  "nodes" : [ {
    "id" : 109280,
    "reactomeId" : 11008691,
    "displayName" : "Homologues of SLC7A3",
    "schemaClass" : "DefinedSet",
    "renderableClass" : "EntitySet",
    "position" : {
      "x" : 451,
      "y" : 1293
    },
    "minX" : 422,
    "maxX" : 514,
    "minY" : 1281,
    "maxY" : 1306,
    "prop" : {
      "x" : 422,
      "y" : 1281,
      "width" : 58,
      "height" : 25
    },
    "textPosition" : {
      "x" : 422,
      "y" : 1269
    },
    "connectors" : [ {
      "edgeId" : 109279,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 483,
          "y" : 1293
        },
        "to" : {
          "x" : 506,
          "y" : 1293
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 510,
          "y" : 1293
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 510,
          "y" : 1293
        }
      }
    } ]
  }, {
    "id" : 109259,
    "reactomeId" : 375400,
    "displayName" : "ligands of SLC36A1",
    "schemaClass" : "DefinedSet",
    "renderableClass" : "EntitySet",
    "position" : {
      "x" : 103,
      "y" : 17
    },
    "minX" : 67,
    "maxX" : 139,
    "minY" : 0,
    "maxY" : 107,
    "prop" : {
      "x" : 67,
      "y" : 0,
      "width" : 72,
      "height" : 34
    },
    "textPosition" : {
      "x" : 67,
      "y" : 0
    },
    "connectors" : [ {
      "edgeId" : 109257,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 104,
          "y" : 40
        },
        "to" : {
          "x" : 112,
          "y" : 107
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 109258,
    "reactomeId" : 351626,
    "displayName" : "H+",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 187,
      "y" : 55
    },
    "minX" : 112,
    "maxX" : 263,
    "minY" : 39,
    "maxY" : 109,
    "prop" : {
      "x" : 172,
      "y" : 40,
      "width" : 31,
      "height" : 31
    },
    "textPosition" : {
      "x" : 174,
      "y" : 45
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 198,
          "y" : 45
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 198,
          "y" : 45
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 109257,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 169,
          "y" : 65
        },
        "to" : {
          "x" : 112,
          "y" : 107
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 109263,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 206,
          "y" : 66
        },
        "to" : {
          "x" : 263,
          "y" : 109
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ],
    "trivial" : true
  }, {
    "id" : 109261,
    "reactomeId" : 375411,
    "displayName" : "ligands of SLC36A1",
    "schemaClass" : "DefinedSet",
    "renderableClass" : "EntitySet",
    "position" : {
      "x" : 108,
      "y" : 173
    },
    "minX" : 72,
    "maxX" : 145,
    "minY" : 111,
    "maxY" : 190,
    "prop" : {
      "x" : 72,
      "y" : 156,
      "width" : 73,
      "height" : 34
    },
    "textPosition" : {
      "x" : 72,
      "y" : 156
    },
    "connectors" : [ {
      "edgeId" : 109257,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 109,
          "y" : 150
        },
        "to" : {
          "x" : 112,
          "y" : 111
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 106,
          "y" : 143
        },
        "b" : {
          "x" : 109,
          "y" : 150
        },
        "c" : {
          "x" : 114,
          "y" : 143
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 114,
          "y" : 143
        }
      }
    } ]
  }, {
    "id" : 109260,
    "reactomeId" : 70106,
    "displayName" : "H+",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 198,
      "y" : 175
    },
    "minX" : 112,
    "maxX" : 263,
    "minY" : 108,
    "maxY" : 191,
    "prop" : {
      "x" : 183,
      "y" : 160,
      "width" : 31,
      "height" : 31
    },
    "textPosition" : {
      "x" : 185,
      "y" : 165
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 209,
          "y" : 165
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 209,
          "y" : 165
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 109257,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 180,
          "y" : 163
        },
        "to" : {
          "x" : 112,
          "y" : 111
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 172,
          "y" : 162
        },
        "b" : {
          "x" : 180,
          "y" : 163
        },
        "c" : {
          "x" : 177,
          "y" : 156
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 177,
          "y" : 156
        }
      }
    }, {
      "edgeId" : 109263,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 213,
          "y" : 157
        },
        "to" : {
          "x" : 263,
          "y" : 108
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 215,
          "y" : 149
        },
        "b" : {
          "x" : 213,
          "y" : 157
        },
        "c" : {
          "x" : 221,
          "y" : 155
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 221,
          "y" : 155
        }
      }
    } ],
    "trivial" : true
  }, {
    "id" : 109262,
    "reactomeId" : 11008632,
    "displayName" : "SLC36A1",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 29,
      "y" : 107
    },
    "minX" : 0,
    "maxX" : 102,
    "minY" : 90,
    "maxY" : 119,
    "prop" : {
      "x" : 0,
      "y" : 96,
      "width" : 59,
      "height" : 23
    },
    "textPosition" : {
      "x" : 2,
      "y" : 90
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 59,
          "y" : 96
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 59,
          "y" : 96
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 109257,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 62,
          "y" : 107
        },
        "to" : {
          "x" : 94,
          "y" : 108
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 98,
          "y" : 108
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 98,
          "y" : 108
        }
      }
    } ]
  }, {
    "id" : 109265,
    "reactomeId" : 375414,
    "displayName" : "Gly, L-Pro",
    "schemaClass" : "DefinedSet",
    "renderableClass" : "EntitySet",
    "position" : {
      "x" : 295,
      "y" : 175
    },
    "minX" : 262,
    "maxX" : 328,
    "minY" : 108,
    "maxY" : 188,
    "prop" : {
      "x" : 262,
      "y" : 163,
      "width" : 66,
      "height" : 25
    },
    "textPosition" : {
      "x" : 262,
      "y" : 165
    },
    "connectors" : [ {
      "edgeId" : 109263,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 289,
          "y" : 157
        },
        "to" : {
          "x" : 263,
          "y" : 108
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 282,
          "y" : 153
        },
        "b" : {
          "x" : 289,
          "y" : 157
        },
        "c" : {
          "x" : 289,
          "y" : 149
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 289,
          "y" : 149
        }
      }
    } ]
  }, {
    "id" : 109264,
    "reactomeId" : 375409,
    "displayName" : "Gly, L-Pro",
    "schemaClass" : "DefinedSet",
    "renderableClass" : "EntitySet",
    "position" : {
      "x" : 281,
      "y" : 14
    },
    "minX" : 249,
    "maxX" : 313,
    "minY" : 2,
    "maxY" : 109,
    "prop" : {
      "x" : 249,
      "y" : 2,
      "width" : 64,
      "height" : 25
    },
    "textPosition" : {
      "x" : 259,
      "y" : -3
    },
    "connectors" : [ {
      "edgeId" : 109263,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 278,
          "y" : 33
        },
        "to" : {
          "x" : 263,
          "y" : 109
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 109266,
    "reactomeId" : 11008627,
    "displayName" : "SLC36A2",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 335,
      "y" : 108
    },
    "minX" : 270,
    "maxX" : 373,
    "minY" : 90,
    "maxY" : 121,
    "prop" : {
      "x" : 303,
      "y" : 96,
      "width" : 64,
      "height" : 25
    },
    "textPosition" : {
      "x" : 304,
      "y" : 98
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 367,
          "y" : 96
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 367,
          "y" : 96
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 109263,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 300,
          "y" : 108
        },
        "to" : {
          "x" : 278,
          "y" : 108
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 274,
          "y" : 108
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 274,
          "y" : 108
        }
      }
    } ]
  }, {
    "id" : 109269,
    "reactomeId" : 113538,
    "displayName" : "L-Pro",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 2338,
      "y" : 458
    },
    "minX" : 2315,
    "maxX" : 2363,
    "minY" : 442,
    "maxY" : 474,
    "prop" : {
      "x" : 2315,
      "y" : 443,
      "width" : 47,
      "height" : 31
    },
    "textPosition" : {
      "x" : 2319,
      "y" : 448
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 2357,
          "y" : 448
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 2357,
          "y" : 448
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 109267,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 109268,
    "reactomeId" : 352033,
    "displayName" : "L-Pro",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 2140,
      "y" : 459
    },
    "minX" : 2117,
    "maxX" : 2165,
    "minY" : 443,
    "maxY" : 475,
    "prop" : {
      "x" : 2117,
      "y" : 444,
      "width" : 47,
      "height" : 31
    },
    "textPosition" : {
      "x" : 2121,
      "y" : 449
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 2159,
          "y" : 449
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 2159,
          "y" : 449
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 109267,
      "type" : "INPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 109270,
    "reactomeId" : 11038801,
    "displayName" : "SLC36A4",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 2241,
      "y" : 515
    },
    "minX" : 2208,
    "maxX" : 2280,
    "minY" : 485,
    "maxY" : 528,
    "prop" : {
      "x" : 2208,
      "y" : 503,
      "width" : 66,
      "height" : 25
    },
    "textPosition" : {
      "x" : 2210,
      "y" : 505
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 2274,
          "y" : 503
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 2274,
          "y" : 503
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 109267,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 2240,
          "y" : 500
        },
        "to" : {
          "x" : 2240,
          "y" : 493
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 2240,
          "y" : 489
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 2240,
          "y" : 489
        }
      }
    } ]
  }, {
    "id" : 109273,
    "reactomeId" : 375781,
    "displayName" : "L-Arg, L-Lys, L-Orn",
    "schemaClass" : "CandidateSet",
    "renderableClass" : "EntitySet",
    "position" : {
      "x" : 308,
      "y" : 1212
    },
    "minX" : 284,
    "maxX" : 332,
    "minY" : 1188,
    "maxY" : 1236,
    "prop" : {
      "x" : 284,
      "y" : 1188,
      "width" : 48,
      "height" : 48
    },
    "textPosition" : {
      "x" : 284,
      "y" : 1188
    },
    "connectors" : [ {
      "edgeId" : 109271,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 109275,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 109277,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 109279,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 109272,
    "reactomeId" : 375765,
    "displayName" : "L-Arg, L-Lys, L-Orn",
    "schemaClass" : "CandidateSet",
    "renderableClass" : "EntitySet",
    "position" : {
      "x" : 311,
      "y" : 1384
    },
    "minX" : 288,
    "maxX" : 335,
    "minY" : 1361,
    "maxY" : 1408,
    "prop" : {
      "x" : 288,
      "y" : 1361,
      "width" : 47,
      "height" : 47
    },
    "textPosition" : {
      "x" : 288,
      "y" : 1360
    },
    "connectors" : [ {
      "edgeId" : 109271,
      "type" : "INPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 109275,
      "type" : "INPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 109277,
      "type" : "INPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 109279,
      "type" : "INPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 109274,
    "reactomeId" : 11008710,
    "displayName" : "Homologues of SLC7A1",
    "schemaClass" : "DefinedSet",
    "renderableClass" : "EntitySet",
    "position" : {
      "x" : 57,
      "y" : 1292
    },
    "minX" : 28,
    "maxX" : 114,
    "minY" : 1280,
    "maxY" : 1305,
    "prop" : {
      "x" : 28,
      "y" : 1280,
      "width" : 58,
      "height" : 25
    },
    "textPosition" : {
      "x" : 28,
      "y" : 1268
    },
    "connectors" : [ {
      "edgeId" : 109271,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 89,
          "y" : 1291
        },
        "to" : {
          "x" : 106,
          "y" : 1291
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 110,
          "y" : 1291
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 110,
          "y" : 1291
        }
      }
    } ]
  }, {
    "id" : 109276,
    "reactomeId" : 11008672,
    "displayName" : "Homologues of SLC7A2-1",
    "schemaClass" : "DefinedSet",
    "renderableClass" : "EntitySet",
    "position" : {
      "x" : 323,
      "y" : 1293
    },
    "minX" : 289,
    "maxX" : 387,
    "minY" : 1281,
    "maxY" : 1306,
    "prop" : {
      "x" : 289,
      "y" : 1281,
      "width" : 68,
      "height" : 25
    },
    "textPosition" : {
      "x" : 290,
      "y" : 1269
    },
    "connectors" : [ {
      "edgeId" : 109275,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 360,
          "y" : 1293
        },
        "to" : {
          "x" : 379,
          "y" : 1294
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 383,
          "y" : 1294
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 383,
          "y" : 1294
        }
      }
    } ]
  }, {
    "id" : 109278,
    "reactomeId" : 11008672,
    "displayName" : "Homologues of SLC7A2-1",
    "schemaClass" : "DefinedSet",
    "renderableClass" : "EntitySet",
    "position" : {
      "x" : 188,
      "y" : 1292
    },
    "minX" : 154,
    "maxX" : 252,
    "minY" : 1280,
    "maxY" : 1305,
    "prop" : {
      "x" : 154,
      "y" : 1280,
      "width" : 68,
      "height" : 25
    },
    "textPosition" : {
      "x" : 155,
      "y" : 1268
    },
    "connectors" : [ {
      "edgeId" : 109277,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 225,
          "y" : 1292
        },
        "to" : {
          "x" : 244,
          "y" : 1293
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 248,
          "y" : 1293
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 248,
          "y" : 1293
        }
      }
    } ]
  } ],
  "edges" : [ {
    "id" : 109267,
    "reactomeId" : 11038807,
    "displayName" : "SLC36A4 transports extracellular L-Pro to the cytosol",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 2239,
      "y" : 477
    },
    "minX" : 2167,
    "maxX" : 2312,
    "minY" : 462,
    "maxY" : 483,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 2167,
        "y" : 463
      },
      "to" : {
        "x" : 2239,
        "y" : 477
      }
    }, {
      "from" : {
        "x" : 2239,
        "y" : 477
      },
      "to" : {
        "x" : 2312,
        "y" : 462
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 2306,
        "y" : 467
      },
      "b" : {
        "x" : 2312,
        "y" : 462
      },
      "c" : {
        "x" : 2304,
        "y" : 459
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 2304,
        "y" : 459
      }
    },
    "reactionShape" : {
      "a" : {
        "x" : 2233,
        "y" : 471
      },
      "b" : {
        "x" : 2245,
        "y" : 483
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 2239,
        "y" : 477
      }
    },
    "inputs" : [ {
      "id" : 109268
    } ],
    "outputs" : [ {
      "id" : 109269
    } ],
    "catalysts" : [ {
      "id" : 109270,
      "points" : [ {
        "x" : 2240,
        "y" : 500
      } ]
    } ]
  }, {
    "id" : 109271,
    "reactomeId" : 11008713,
    "displayName" : "SLC7A1 (CAT-1)-mediated uptake of cationic amino acids",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 122,
      "y" : 1291
    },
    "minX" : 116,
    "maxX" : 282,
    "minY" : 1222,
    "maxY" : 1372,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 282,
        "y" : 1372
      },
      "to" : {
        "x" : 122,
        "y" : 1291
      }
    }, {
      "from" : {
        "x" : 122,
        "y" : 1291
      },
      "to" : {
        "x" : 278,
        "y" : 1222
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 273,
        "y" : 1228
      },
      "b" : {
        "x" : 278,
        "y" : 1222
      },
      "c" : {
        "x" : 270,
        "y" : 1221
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 270,
        "y" : 1221
      }
    },
    "reactionShape" : {
      "a" : {
        "x" : 116,
        "y" : 1285
      },
      "b" : {
        "x" : 128,
        "y" : 1297
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 122,
        "y" : 1291
      }
    },
    "inputs" : [ {
      "id" : 109272
    } ],
    "outputs" : [ {
      "id" : 109273
    } ],
    "catalysts" : [ {
      "id" : 109274,
      "points" : [ {
        "x" : 89,
        "y" : 1291
      } ]
    } ]
  }, {
    "id" : 109257,
    "reactomeId" : 11008635,
    "displayName" : "SLC36A1-mediated uptake of glycine, proline, and alanine",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 110,
      "y" : 108
    },
    "minX" : 104,
    "maxX" : 116,
    "minY" : 102,
    "maxY" : 114,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 112,
        "y" : 107
      },
      "to" : {
        "x" : 110,
        "y" : 108
      }
    }, {
      "from" : {
        "x" : 110,
        "y" : 108
      },
      "to" : {
        "x" : 112,
        "y" : 111
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 104,
        "y" : 102
      },
      "b" : {
        "x" : 116,
        "y" : 114
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 110,
        "y" : 108
      }
    },
    "inputs" : [ {
      "id" : 109258,
      "points" : [ {
        "x" : 169,
        "y" : 65
      } ]
    }, {
      "id" : 109259,
      "points" : [ {
        "x" : 104,
        "y" : 40
      } ]
    } ],
    "outputs" : [ {
      "id" : 109260,
      "points" : [ {
        "x" : 180,
        "y" : 163
      } ]
    }, {
      "id" : 109261,
      "points" : [ {
        "x" : 109,
        "y" : 150
      } ]
    } ],
    "catalysts" : [ {
      "id" : 109262,
      "points" : [ {
        "x" : 62,
        "y" : 107
      } ]
    } ]
  }, {
    "id" : 109275,
    "reactomeId" : 11008715,
    "displayName" : "SLC7A2, isoform A (CAT-2A)-mediated uptake of cationic amino acids",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 395,
      "y" : 1294
    },
    "minX" : 332,
    "maxX" : 401,
    "minY" : 1234,
    "maxY" : 1355,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 332,
        "y" : 1355
      },
      "to" : {
        "x" : 395,
        "y" : 1294
      }
    }, {
      "from" : {
        "x" : 395,
        "y" : 1294
      },
      "to" : {
        "x" : 338,
        "y" : 1234
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 346,
        "y" : 1236
      },
      "b" : {
        "x" : 338,
        "y" : 1234
      },
      "c" : {
        "x" : 340,
        "y" : 1242
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 340,
        "y" : 1242
      }
    },
    "reactionShape" : {
      "a" : {
        "x" : 389,
        "y" : 1288
      },
      "b" : {
        "x" : 401,
        "y" : 1300
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 395,
        "y" : 1294
      }
    },
    "inputs" : [ {
      "id" : 109272
    } ],
    "outputs" : [ {
      "id" : 109273
    } ],
    "catalysts" : [ {
      "id" : 109276,
      "points" : [ {
        "x" : 360,
        "y" : 1293
      } ]
    } ]
  }, {
    "id" : 109277,
    "reactomeId" : 11008675,
    "displayName" : "SLC7A2, isoform B (CAT-2B)-mediated uptake of cationic amino acids",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 260,
      "y" : 1293
    },
    "minX" : 254,
    "maxX" : 297,
    "minY" : 1242,
    "maxY" : 1355,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 297,
        "y" : 1355
      },
      "to" : {
        "x" : 260,
        "y" : 1293
      }
    }, {
      "from" : {
        "x" : 260,
        "y" : 1293
      },
      "to" : {
        "x" : 293,
        "y" : 1242
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 293,
        "y" : 1250
      },
      "b" : {
        "x" : 293,
        "y" : 1242
      },
      "c" : {
        "x" : 286,
        "y" : 1246
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 286,
        "y" : 1246
      }
    },
    "reactionShape" : {
      "a" : {
        "x" : 254,
        "y" : 1287
      },
      "b" : {
        "x" : 266,
        "y" : 1299
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 260,
        "y" : 1293
      }
    },
    "inputs" : [ {
      "id" : 109272
    } ],
    "outputs" : [ {
      "id" : 109273
    } ],
    "catalysts" : [ {
      "id" : 109278,
      "points" : [ {
        "x" : 225,
        "y" : 1292
      } ]
    } ]
  }, {
    "id" : 109279,
    "reactomeId" : 11008694,
    "displayName" : "SLC7A3 (CAT-3)-mediated uptake of cationic amino acids",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 522,
      "y" : 1293
    },
    "minX" : 338,
    "maxX" : 528,
    "minY" : 1221,
    "maxY" : 1373,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 341,
        "y" : 1373
      },
      "to" : {
        "x" : 522,
        "y" : 1293
      }
    }, {
      "from" : {
        "x" : 522,
        "y" : 1293
      },
      "to" : {
        "x" : 338,
        "y" : 1221
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 346,
        "y" : 1220
      },
      "b" : {
        "x" : 338,
        "y" : 1221
      },
      "c" : {
        "x" : 343,
        "y" : 1227
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 343,
        "y" : 1227
      }
    },
    "reactionShape" : {
      "a" : {
        "x" : 516,
        "y" : 1287
      },
      "b" : {
        "x" : 528,
        "y" : 1299
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 522,
        "y" : 1293
      }
    },
    "inputs" : [ {
      "id" : 109272
    } ],
    "outputs" : [ {
      "id" : 109273
    } ],
    "catalysts" : [ {
      "id" : 109280,
      "points" : [ {
        "x" : 483,
        "y" : 1293
      } ]
    } ]
  }, {
    "id" : 109263,
    "reactomeId" : 11008630,
    "displayName" : "SLC36A2 cotransports Gly, L-Pro with H+ from extracellular region to cytosol",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 262,
      "y" : 108
    },
    "minX" : 256,
    "maxX" : 268,
    "minY" : 102,
    "maxY" : 114,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 263,
        "y" : 109
      },
      "to" : {
        "x" : 262,
        "y" : 108
      }
    }, {
      "from" : {
        "x" : 262,
        "y" : 108
      },
      "to" : {
        "x" : 263,
        "y" : 108
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 256,
        "y" : 102
      },
      "b" : {
        "x" : 268,
        "y" : 114
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 262,
        "y" : 108
      }
    },
    "inputs" : [ {
      "id" : 109258,
      "points" : [ {
        "x" : 206,
        "y" : 66
      } ]
    }, {
      "id" : 109264,
      "points" : [ {
        "x" : 278,
        "y" : 33
      } ]
    } ],
    "outputs" : [ {
      "id" : 109265,
      "points" : [ {
        "x" : 289,
        "y" : 157
      } ]
    }, {
      "id" : 109260,
      "points" : [ {
        "x" : 213,
        "y" : 157
      } ]
    } ],
    "catalysts" : [ {
      "id" : 109266,
      "points" : [ {
        "x" : 300,
        "y" : 108
      } ]
    } ]
  } ],
  "compartments" : [ {
    "id" : 109281,
    "reactomeId" : 70101,
    "displayName" : "cytosol",
    "schemaClass" : "Compartment",
    "renderableClass" : "Compartment",
    "position" : {
      "x" : 1133,
      "y" : 699
    },
    "minX" : 21,
    "maxX" : 2246,
    "minY" : 102,
    "maxY" : 1296,
    "prop" : {
      "x" : 21,
      "y" : 102,
      "width" : 2225,
      "height" : 1194
    },
    "textPosition" : {
      "x" : 940,
      "y" : 510
    },
    "insets" : {
      "x" : 31,
      "y" : 112,
      "width" : 2205,
      "height" : 1174
    },
    "bgColor" : {
      "r" : 250,
      "g" : 240,
      "b" : 240
    },
    "componentIds" : [ 109261, 109262, 109260, 109257, 109266, 109265, 109263, 109267, 109270, 109268, 109273, 109274, 109276, 109278, 109280, 109271, 109277, 109279, 109275 ]
  } ],
  "notes" : [ ],
  "links" : [ ],
  "shadows" : [ {
    "id" : 109283,
    "reactomeId" : 11049844,
    "displayName" : "Amino acid transport across the plasma membrane",
    "schemaClass" : "Pathway",
    "renderableClass" : "Shadow",
    "position" : {
      "x" : 1181,
      "y" : 704
    },
    "minX" : -10,
    "maxX" : 2372,
    "minY" : -10,
    "maxY" : 1418,
    "prop" : {
      "x" : -10,
      "y" : 201,
      "width" : 2382,
      "height" : 1217
    },
    "points" : [ {
      "x" : -10,
      "y" : -10
    }, {
      "x" : 2372,
      "y" : -10
    }, {
      "x" : 2372,
      "y" : 1418
    }, {
      "x" : -10,
      "y" : 1418
    } ],
    "colour" : "#dc3912"
  }, {
    "id" : 109282,
    "reactomeId" : 11049840,
    "displayName" : "Proton-coupled neutral amino acid transporters",
    "schemaClass" : "Pathway",
    "renderableClass" : "Shadow",
    "position" : {
      "x" : 183,
      "y" : 95
    },
    "minX" : -10,
    "maxX" : 377,
    "minY" : -10,
    "maxY" : 201,
    "prop" : {
      "x" : -10,
      "y" : -10,
      "width" : 387,
      "height" : 211
    },
    "points" : [ {
      "x" : -10,
      "y" : -10
    }, {
      "x" : 377,
      "y" : -10
    }, {
      "x" : 377,
      "y" : 201
    }, {
      "x" : -10,
      "y" : 201
    } ],
    "colour" : "#4684ee"
  } ],
  "minX" : 0,
  "maxX" : 2363,
  "minY" : 0,
  "maxY" : 1408,
  "disease" : false
}