{ "dbId" : 11049062, "stableId" : "R-DDI-8956319", "displayName" : "Nucleotide catabolism", "nodes" : [ { "id" : 137751, "reactomeId" : 8866574, "displayName" : "dNTP(4-)", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 1325, "y" : 372 }, "minX" : 1289, "maxX" : 1372, "minY" : 356, "maxY" : 405, "prop" : { "x" : 1289, "y" : 357, "width" : 72, "height" : 31 }, "textPosition" : { "x" : 1294, "y" : 362 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1356, "y" : 362 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1356, "y" : 362 } } }, "connectors" : [ { "edgeId" : 137750, "type" : "INPUT", "segments" : [ { "from" : { "x" : 1347, "y" : 391 }, "to" : { "x" : 1372, "y" : 405 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 137754, "reactomeId" : 8866608, "displayName" : "2'-deoxynucleoside", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 1380, "y" : 532 }, "minX" : 1315, "maxX" : 1447, "minY" : 473, "maxY" : 548, "prop" : { "x" : 1315, "y" : 517, "width" : 131, "height" : 31 }, "textPosition" : { "x" : 1317, "y" : 522 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1441, "y" : 522 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1441, "y" : 522 } } }, "connectors" : [ { "edgeId" : 137750, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 1378, "y" : 514 }, "to" : { "x" : 1376, "y" : 473 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 1374, "y" : 507 }, "b" : { "x" : 1378, "y" : 514 }, "c" : { "x" : 1382, "y" : 507 }, "type" : "ARROW", "centre" : { "x" : 1382, "y" : 507 } } } ] }, { "id" : 137755, "reactomeId" : 9668967, "displayName" : "H+", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 1327, "y" : 485 }, "minX" : 1309, "maxX" : 1376, "minY" : 469, "maxY" : 501, "prop" : { "x" : 1309, "y" : 470, "width" : 36, "height" : 31 }, "textPosition" : { "x" : 1313, "y" : 475 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1340, "y" : 475 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1340, "y" : 475 } } }, "connectors" : [ { "edgeId" : 137750, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 1348, "y" : 480 }, "to" : { "x" : 1376, "y" : 473 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 1354, "y" : 474 }, "b" : { "x" : 1348, "y" : 480 }, "c" : { "x" : 1356, "y" : 482 }, "type" : "ARROW", "centre" : { "x" : 1356, "y" : 482 } } } ], "trivial" : true }, { "id" : 137752, "reactomeId" : 113518, "displayName" : "H2O", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 1439, "y" : 370 }, "minX" : 1372, "maxX" : 1462, "minY" : 354, "maxY" : 405, "prop" : { "x" : 1418, "y" : 355, "width" : 43, "height" : 31 }, "textPosition" : { "x" : 1422, "y" : 360 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1456, "y" : 360 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1456, "y" : 360 } } }, "connectors" : [ { "edgeId" : 137750, "type" : "INPUT", "segments" : [ { "from" : { "x" : 1415, "y" : 381 }, "to" : { "x" : 1372, "y" : 405 } } ], "stoichiometry" : { "value" : 1 } } ], "trivial" : true }, { "id" : 137753, "reactomeId" : 8866567, "displayName" : "PPPi", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 1425, "y" : 487 }, "minX" : 1376, "maxX" : 1447, "minY" : 471, "maxY" : 503, "prop" : { "x" : 1405, "y" : 472, "width" : 41, "height" : 31 }, "textPosition" : { "x" : 1408, "y" : 477 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1441, "y" : 477 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1441, "y" : 477 } } }, "connectors" : [ { "edgeId" : 137750, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 1402, "y" : 481 }, "to" : { "x" : 1376, "y" : 473 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 1394, "y" : 483 }, "b" : { "x" : 1402, "y" : 481 }, "c" : { "x" : 1397, "y" : 475 }, "type" : "ARROW", "centre" : { "x" : 1397, "y" : 475 } } } ] }, { "id" : 137759, "reactomeId" : 500120, "displayName" : "(d)GMP, (d)IMP", "schemaClass" : "DefinedSet", "renderableClass" : "EntitySet", "position" : { "x" : 165, "y" : 64 }, "minX" : 118, "maxX" : 213, "minY" : 53, "maxY" : 134, "prop" : { "x" : 118, "y" : 53, "width" : 95, "height" : 23 }, "textPosition" : { "x" : 126, "y" : 47 }, "connectors" : [ { "edgeId" : 137758, "type" : "INPUT", "segments" : [ { "from" : { "x" : 168, "y" : 82 }, "to" : { "x" : 185, "y" : 134 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 137756, "reactomeId" : 11038393, "displayName" : "SAMHD1:Zn2+ tetramer", "schemaClass" : "Complex", "renderableClass" : "Complex", "position" : { "x" : 1459, "y" : 437 }, "minX" : 1383, "maxX" : 1515, "minY" : 413, "maxY" : 456, "prop" : { "x" : 1410, "y" : 419, "width" : 99, "height" : 37 }, "textPosition" : { "x" : 1408, "y" : 421 }, "bgColor" : { "r" : 204, "g" : 255, "b" : 255 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1509, "y" : 419 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1509, "y" : 419 } } }, "connectors" : [ { "edgeId" : 137750, "type" : "CATALYST", "segments" : [ { "from" : { "x" : 1407, "y" : 434 }, "to" : { "x" : 1391, "y" : 433 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "c" : { "x" : 1387, "y" : 433 }, "r" : 4, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1387, "y" : 433 } } } ] }, { "id" : 137757, "reactomeId" : 29892, "displayName" : "dGTP", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 1317, "y" : 430 }, "minX" : 1293, "maxX" : 1366, "minY" : 414, "maxY" : 446, "prop" : { "x" : 1293, "y" : 415, "width" : 49, "height" : 31 }, "textPosition" : { "x" : 1297, "y" : 420 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1337, "y" : 420 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1337, "y" : 420 } } }, "connectors" : [ { "edgeId" : 137750, "type" : "ACTIVATOR", "segments" : [ { "from" : { "x" : 1345, "y" : 431 }, "to" : { "x" : 1366, "y" : 432 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 1359, "y" : 436 }, "b" : { "x" : 1366, "y" : 432 }, "c" : { "x" : 1359, "y" : 428 }, "type" : "ARROW", "empty" : true, "centre" : { "x" : 1359, "y" : 428 } } } ] }, { "id" : 137762, "reactomeId" : 29372, "displayName" : "Pi", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 226, "y" : 220 }, "minX" : 186, "maxX" : 241, "minY" : 204, "maxY" : 236, "prop" : { "x" : 213, "y" : 205, "width" : 27, "height" : 31 }, "textPosition" : { "x" : 217, "y" : 210 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 235, "y" : 210 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 235, "y" : 210 } } }, "connectors" : [ { "edgeId" : 137758, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 210, "y" : 215 }, "to" : { "x" : 186, "y" : 207 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 202, "y" : 217 }, "b" : { "x" : 210, "y" : 215 }, "c" : { "x" : 205, "y" : 209 }, "type" : "ARROW", "centre" : { "x" : 205, "y" : 209 } } } ] }, { "id" : 137763, "reactomeId" : 11000768, "displayName" : "NT5C2 tetramer", "schemaClass" : "Complex", "renderableClass" : "Complex", "position" : { "x" : 77, "y" : 186 }, "minX" : 25, "maxX" : 178, "minY" : 169, "maxY" : 198, "prop" : { "x" : 25, "y" : 175, "width" : 104, "height" : 23 }, "textPosition" : { "x" : 45, "y" : 163 }, "bgColor" : { "r" : 204, "g" : 255, "b" : 255 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 129, "y" : 175 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 129, "y" : 175 } } }, "connectors" : [ { "edgeId" : 137758, "type" : "CATALYST", "segments" : [ { "from" : { "x" : 132, "y" : 182 }, "to" : { "x" : 170, "y" : 180 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "c" : { "x" : 174, "y" : 180 }, "r" : 4, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 174, "y" : 180 } } } ] }, { "id" : 137760, "reactomeId" : 29356, "displayName" : "H2O", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 220, "y" : 107 }, "minX" : 185, "maxX" : 243, "minY" : 91, "maxY" : 134, "prop" : { "x" : 199, "y" : 92, "width" : 43, "height" : 31 }, "textPosition" : { "x" : 203, "y" : 97 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 237, "y" : 97 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 237, "y" : 97 } } }, "connectors" : [ { "edgeId" : 137758, "type" : "INPUT", "segments" : [ { "from" : { "x" : 199, "y" : 126 }, "to" : { "x" : 185, "y" : 134 } } ], "stoichiometry" : { "value" : 1 } } ], "trivial" : true }, { "id" : 137761, "reactomeId" : 500118, "displayName" : "Gu-Rib, dG, Ino, dI", "schemaClass" : "DefinedSet", "renderableClass" : "EntitySet", "position" : { "x" : 168, "y" : 269 }, "minX" : 108, "maxX" : 228, "minY" : 207, "maxY" : 281, "prop" : { "x" : 108, "y" : 258, "width" : 120, "height" : 23 }, "textPosition" : { "x" : 108, "y" : 259 }, "connectors" : [ { "edgeId" : 137758, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 171, "y" : 252 }, "to" : { "x" : 186, "y" : 207 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 169, "y" : 244 }, "b" : { "x" : 171, "y" : 252 }, "c" : { "x" : 177, "y" : 247 }, "type" : "ARROW", "centre" : { "x" : 177, "y" : 247 } } } ] }, { "id" : 137766, "reactomeId" : 83956, "displayName" : "Gua", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 189, "y" : 579 }, "minX" : 169, "maxX" : 210, "minY" : 563, "maxY" : 638, "prop" : { "x" : 169, "y" : 564, "width" : 40, "height" : 31 }, "textPosition" : { "x" : 172, "y" : 569 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 204, "y" : 569 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 204, "y" : 569 } } }, "connectors" : [ { "edgeId" : 137764, "type" : "INPUT", "segments" : [ { "from" : { "x" : 189, "y" : 598 }, "to" : { "x" : 190, "y" : 638 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 137767, "reactomeId" : 70106, "displayName" : "H+", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 228, "y" : 617 }, "minX" : 190, "maxX" : 249, "minY" : 600, "maxY" : 638, "prop" : { "x" : 209, "y" : 601, "width" : 39, "height" : 32 }, "textPosition" : { "x" : 215, "y" : 606 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 243, "y" : 606 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 243, "y" : 606 } } }, "connectors" : [ { "edgeId" : 137764, "type" : "INPUT", "segments" : [ { "from" : { "x" : 206, "y" : 627 }, "to" : { "x" : 190, "y" : 638 } } ], "stoichiometry" : { "value" : 1 } } ], "trivial" : true }, { "id" : 137765, "reactomeId" : 29356, "displayName" : "H2O", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 144, "y" : 618 }, "minX" : 123, "maxX" : 190, "minY" : 602, "maxY" : 638, "prop" : { "x" : 123, "y" : 603, "width" : 43, "height" : 31 }, "textPosition" : { "x" : 127, "y" : 608 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 161, "y" : 608 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 161, "y" : 608 } } }, "connectors" : [ { "edgeId" : 137764, "type" : "INPUT", "segments" : [ { "from" : { "x" : 169, "y" : 627 }, "to" : { "x" : 190, "y" : 638 } } ], "stoichiometry" : { "value" : 1 } } ], "trivial" : true }, { "id" : 137770, "reactomeId" : 11000778, "displayName" : "GDA dimer", "schemaClass" : "Complex", "renderableClass" : "Complex", "position" : { "x" : 102, "y" : 678 }, "minX" : 66, "maxX" : 183, "minY" : 661, "maxY" : 690, "prop" : { "x" : 66, "y" : 667, "width" : 73, "height" : 23 }, "textPosition" : { "x" : 66, "y" : 669 }, "bgColor" : { "r" : 204, "g" : 255, "b" : 255 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 139, "y" : 667 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 139, "y" : 667 } } }, "connectors" : [ { "edgeId" : 137764, "type" : "CATALYST", "segments" : [ { "from" : { "x" : 142, "y" : 678 }, "to" : { "x" : 175, "y" : 678 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "c" : { "x" : 179, "y" : 678 }, "r" : 4, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 179, "y" : 678 } } } ] }, { "id" : 137768, "reactomeId" : 30064, "displayName" : "XAN", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 347, "y" : 720 }, "minX" : 191, "maxX" : 376, "minY" : 658, "maxY" : 764, "prop" : { "x" : 326, "y" : 705, "width" : 42, "height" : 31 }, "textPosition" : { "x" : 331, "y" : 710 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 363, "y" : 710 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 363, "y" : 710 } } }, "connectors" : [ { "edgeId" : 137764, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 323, "y" : 718 }, "to" : { "x" : 191, "y" : 711 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 316, "y" : 722 }, "b" : { "x" : 323, "y" : 718 }, "c" : { "x" : 316, "y" : 714 }, "type" : "ARROW", "centre" : { "x" : 316, "y" : 714 } } }, { "edgeId" : 137771, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 340, "y" : 702 }, "to" : { "x" : 322, "y" : 658 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 334, "y" : 697 }, "b" : { "x" : 340, "y" : 702 }, "c" : { "x" : 341, "y" : 694 }, "type" : "ARROW", "centre" : { "x" : 341, "y" : 694 } } }, { "edgeId" : 137777, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 356, "y" : 702 }, "to" : { "x" : 376, "y" : 675 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 357, "y" : 694 }, "b" : { "x" : 356, "y" : 702 }, "c" : { "x" : 363, "y" : 699 }, "type" : "ARROW", "centre" : { "x" : 363, "y" : 699 } } }, { "edgeId" : 137782, "type" : "INPUT", "segments" : [ { "from" : { "x" : 338, "y" : 739 }, "to" : { "x" : 324, "y" : 764 } } ], "stoichiometry" : { "value" : 1 } }, { "edgeId" : 137787, "type" : "INPUT", "segments" : [ { "from" : { "x" : 357, "y" : 739 }, "to" : { "x" : 375, "y" : 763 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 137769, "reactomeId" : 31633, "displayName" : "NH4+", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 125, "y" : 752 }, "minX" : 99, "maxX" : 191, "minY" : 711, "maxY" : 768, "prop" : { "x" : 99, "y" : 737, "width" : 53, "height" : 31 }, "textPosition" : { "x" : 103, "y" : 742 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 147, "y" : 742 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 147, "y" : 742 } } }, "connectors" : [ { "edgeId" : 137764, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 149, "y" : 734 }, "to" : { "x" : 191, "y" : 711 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 153, "y" : 727 }, "b" : { "x" : 149, "y" : 734 }, "c" : { "x" : 157, "y" : 734 }, "type" : "ARROW", "centre" : { "x" : 157, "y" : 734 } } } ] }, { "id" : 137774, "reactomeId" : 29356, "displayName" : "H2O", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 289, "y" : 560 }, "minX" : 268, "maxX" : 322, "minY" : 544, "maxY" : 604, "prop" : { "x" : 268, "y" : 545, "width" : 43, "height" : 31 }, "textPosition" : { "x" : 272, "y" : 550 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 306, "y" : 550 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 306, "y" : 550 } } }, "connectors" : [ { "edgeId" : 137771, "type" : "INPUT", "segments" : [ { "from" : { "x" : 300, "y" : 579 }, "to" : { "x" : 322, "y" : 604 } } ], "stoichiometry" : { "value" : 1 } } ], "trivial" : true }, { "id" : 137775, "reactomeId" : 29408, "displayName" : "H2O2", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 278, "y" : 676 }, "minX" : 253, "maxX" : 322, "minY" : 658, "maxY" : 692, "prop" : { "x" : 253, "y" : 661, "width" : 51, "height" : 31 }, "textPosition" : { "x" : 257, "y" : 666 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 299, "y" : 666 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 299, "y" : 666 } } }, "connectors" : [ { "edgeId" : 137771, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 307, "y" : 665 }, "to" : { "x" : 322, "y" : 658 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 312, "y" : 658 }, "b" : { "x" : 307, "y" : 665 }, "c" : { "x" : 315, "y" : 666 }, "type" : "ARROW", "centre" : { "x" : 315, "y" : 666 } } } ] }, { "id" : 137772, "reactomeId" : 113599, "displayName" : "Hyp", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 347, "y" : 540 }, "minX" : 322, "maxX" : 375, "minY" : 524, "maxY" : 604, "prop" : { "x" : 327, "y" : 525, "width" : 40, "height" : 31 }, "textPosition" : { "x" : 331, "y" : 530 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 362, "y" : 530 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 362, "y" : 530 } } }, "connectors" : [ { "edgeId" : 137771, "type" : "INPUT", "segments" : [ { "from" : { "x" : 340, "y" : 559 }, "to" : { "x" : 322, "y" : 604 } } ], "stoichiometry" : { "value" : 1 } }, { "edgeId" : 137777, "type" : "INPUT", "segments" : [ { "from" : { "x" : 354, "y" : 559 }, "to" : { "x" : 375, "y" : 595 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 137773, "reactomeId" : 29368, "displayName" : "O2", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 281, "y" : 598 }, "minX" : 264, "maxX" : 322, "minY" : 582, "maxY" : 614, "prop" : { "x" : 264, "y" : 583, "width" : 34, "height" : 31 }, "textPosition" : { "x" : 268, "y" : 588 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 293, "y" : 588 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 293, "y" : 588 } } }, "connectors" : [ { "edgeId" : 137771, "type" : "INPUT", "segments" : [ { "from" : { "x" : 301, "y" : 600 }, "to" : { "x" : 322, "y" : 604 } } ], "stoichiometry" : { "value" : 1 } } ], "trivial" : true }, { "id" : 137778, "reactomeId" : 29360, "displayName" : "NAD+", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 413, "y" : 542 }, "minX" : 375, "maxX" : 441, "minY" : 526, "maxY" : 595, "prop" : { "x" : 387, "y" : 527, "width" : 53, "height" : 31 }, "textPosition" : { "x" : 391, "y" : 532 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 435, "y" : 532 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 435, "y" : 532 } } }, "connectors" : [ { "edgeId" : 137777, "type" : "INPUT", "segments" : [ { "from" : { "x" : 401, "y" : 561 }, "to" : { "x" : 375, "y" : 595 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 137779, "reactomeId" : 29356, "displayName" : "H2O", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 450, "y" : 585 }, "minX" : 375, "maxX" : 473, "minY" : 569, "maxY" : 601, "prop" : { "x" : 429, "y" : 570, "width" : 43, "height" : 31 }, "textPosition" : { "x" : 433, "y" : 575 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 467, "y" : 575 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 467, "y" : 575 } } }, "connectors" : [ { "edgeId" : 137777, "type" : "INPUT", "segments" : [ { "from" : { "x" : 426, "y" : 587 }, "to" : { "x" : 375, "y" : 595 } } ], "stoichiometry" : { "value" : 1 } } ], "trivial" : true }, { "id" : 137776, "reactomeId" : 11000758, "displayName" : "XDH dimer", "schemaClass" : "Complex", "renderableClass" : "Complex", "position" : { "x" : 506, "y" : 632 }, "minX" : 331, "maxX" : 549, "minY" : 615, "maxY" : 816, "prop" : { "x" : 470, "y" : 621, "width" : 73, "height" : 23 }, "textPosition" : { "x" : 470, "y" : 623 }, "bgColor" : { "r" : 204, "g" : 255, "b" : 255 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 543, "y" : 621 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 543, "y" : 621 } } }, "connectors" : [ { "edgeId" : 137771, "type" : "CATALYST", "segments" : [ { "from" : { "x" : 467, "y" : 631 }, "to" : { "x" : 339, "y" : 627 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "c" : { "x" : 335, "y" : 627 }, "r" : 4, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 335, "y" : 627 } } }, { "edgeId" : 137777, "type" : "CATALYST", "segments" : [ { "from" : { "x" : 467, "y" : 634 }, "to" : { "x" : 392, "y" : 641 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "c" : { "x" : 388, "y" : 641 }, "r" : 4, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 388, "y" : 641 } } }, { "edgeId" : 137782, "type" : "CATALYST", "segments" : [ { "from" : { "x" : 506, "y" : 647 }, "to" : { "x" : 506, "y" : 780 } }, { "from" : { "x" : 506, "y" : 780 }, "to" : { "x" : 340, "y" : 801 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "c" : { "x" : 336, "y" : 801 }, "r" : 4, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 336, "y" : 801 } } }, { "edgeId" : 137787, "type" : "CATALYST", "segments" : [ { "from" : { "x" : 507, "y" : 647 }, "to" : { "x" : 523, "y" : 789 } }, { "from" : { "x" : 523, "y" : 789 }, "to" : { "x" : 393, "y" : 811 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "c" : { "x" : 389, "y" : 812 }, "r" : 4, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 389, "y" : 812 } } } ] }, { "id" : 137783, "reactomeId" : 29368, "displayName" : "O2", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 261, "y" : 739 }, "minX" : 244, "maxX" : 324, "minY" : 723, "maxY" : 764, "prop" : { "x" : 244, "y" : 724, "width" : 34, "height" : 31 }, "textPosition" : { "x" : 248, "y" : 729 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 273, "y" : 729 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 273, "y" : 729 } } }, "connectors" : [ { "edgeId" : 137782, "type" : "INPUT", "segments" : [ { "from" : { "x" : 281, "y" : 745 }, "to" : { "x" : 324, "y" : 764 } } ], "stoichiometry" : { "value" : 1 } } ], "trivial" : true }, { "id" : 137780, "reactomeId" : 73473, "displayName" : "NADH", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 434, "y" : 666 }, "minX" : 376, "maxX" : 461, "minY" : 650, "maxY" : 682, "prop" : { "x" : 408, "y" : 651, "width" : 52, "height" : 31 }, "textPosition" : { "x" : 412, "y" : 656 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 455, "y" : 656 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 455, "y" : 656 } } }, "connectors" : [ { "edgeId" : 137777, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 405, "y" : 670 }, "to" : { "x" : 376, "y" : 675 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 399, "y" : 675 }, "b" : { "x" : 405, "y" : 670 }, "c" : { "x" : 397, "y" : 667 }, "type" : "ARROW", "centre" : { "x" : 397, "y" : 667 } } } ] }, { "id" : 137781, "reactomeId" : 70106, "displayName" : "H+", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 407, "y" : 715 }, "minX" : 376, "maxX" : 426, "minY" : 675, "maxY" : 731, "prop" : { "x" : 389, "y" : 700, "width" : 36, "height" : 31 }, "textPosition" : { "x" : 393, "y" : 705 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 420, "y" : 705 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 420, "y" : 705 } } }, "connectors" : [ { "edgeId" : 137777, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 394, "y" : 697 }, "to" : { "x" : 376, "y" : 675 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 387, "y" : 694 }, "b" : { "x" : 394, "y" : 697 }, "c" : { "x" : 393, "y" : 689 }, "type" : "ARROW", "centre" : { "x" : 393, "y" : 689 } } } ], "trivial" : true }, { "id" : 137786, "reactomeId" : 29408, "displayName" : "H2O2", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 270, "y" : 858 }, "minX" : 245, "maxX" : 322, "minY" : 834, "maxY" : 874, "prop" : { "x" : 245, "y" : 843, "width" : 51, "height" : 31 }, "textPosition" : { "x" : 249, "y" : 848 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 291, "y" : 848 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 291, "y" : 848 } } }, "connectors" : [ { "edgeId" : 137782, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 299, "y" : 846 }, "to" : { "x" : 322, "y" : 834 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 303, "y" : 839 }, "b" : { "x" : 299, "y" : 846 }, "c" : { "x" : 307, "y" : 846 }, "type" : "ARROW", "centre" : { "x" : 307, "y" : 846 } } } ] }, { "id" : 137784, "reactomeId" : 29356, "displayName" : "H2O", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 261, "y" : 780 }, "minX" : 240, "maxX" : 324, "minY" : 764, "maxY" : 796, "prop" : { "x" : 240, "y" : 765, "width" : 43, "height" : 31 }, "textPosition" : { "x" : 244, "y" : 770 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 278, "y" : 770 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 278, "y" : 770 } } }, "connectors" : [ { "edgeId" : 137782, "type" : "INPUT", "segments" : [ { "from" : { "x" : 286, "y" : 774 }, "to" : { "x" : 324, "y" : 764 } } ], "stoichiometry" : { "value" : 1 } } ], "trivial" : true }, { "id" : 137785, "reactomeId" : 30034, "displayName" : "urate", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 339, "y" : 884 }, "minX" : 316, "maxX" : 377, "minY" : 834, "maxY" : 900, "prop" : { "x" : 316, "y" : 869, "width" : 47, "height" : 31 }, "textPosition" : { "x" : 318, "y" : 874 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 358, "y" : 874 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 358, "y" : 874 } } }, "connectors" : [ { "edgeId" : 137782, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 333, "y" : 866 }, "to" : { "x" : 322, "y" : 834 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 327, "y" : 861 }, "b" : { "x" : 333, "y" : 866 }, "c" : { "x" : 335, "y" : 858 }, "type" : "ARROW", "centre" : { "x" : 335, "y" : 858 } } }, { "edgeId" : 137787, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 354, "y" : 866 }, "to" : { "x" : 377, "y" : 846 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 357, "y" : 858 }, "b" : { "x" : 354, "y" : 866 }, "c" : { "x" : 362, "y" : 864 }, "type" : "ARROW", "centre" : { "x" : 362, "y" : 864 } } } ] }, { "id" : 137790, "reactomeId" : 73473, "displayName" : "NADH", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 439, "y" : 845 }, "minX" : 377, "maxX" : 466, "minY" : 829, "maxY" : 861, "prop" : { "x" : 413, "y" : 830, "width" : 52, "height" : 31 }, "textPosition" : { "x" : 417, "y" : 835 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 460, "y" : 835 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 460, "y" : 835 } } }, "connectors" : [ { "edgeId" : 137787, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 410, "y" : 845 }, "to" : { "x" : 377, "y" : 846 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 403, "y" : 849 }, "b" : { "x" : 410, "y" : 845 }, "c" : { "x" : 403, "y" : 841 }, "type" : "ARROW", "centre" : { "x" : 403, "y" : 841 } } } ] }, { "id" : 137791, "reactomeId" : 70106, "displayName" : "H+", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 427, "y" : 894 }, "minX" : 377, "maxX" : 446, "minY" : 846, "maxY" : 910, "prop" : { "x" : 409, "y" : 879, "width" : 36, "height" : 31 }, "textPosition" : { "x" : 413, "y" : 884 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 440, "y" : 884 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 440, "y" : 884 } } }, "connectors" : [ { "edgeId" : 137787, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 410, "y" : 876 }, "to" : { "x" : 377, "y" : 846 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 402, "y" : 874 }, "b" : { "x" : 410, "y" : 876 }, "c" : { "x" : 408, "y" : 868 }, "type" : "ARROW", "centre" : { "x" : 408, "y" : 868 } } } ], "trivial" : true }, { "id" : 137788, "reactomeId" : 29356, "displayName" : "H2O", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 456, "y" : 753 }, "minX" : 375, "maxX" : 479, "minY" : 737, "maxY" : 769, "prop" : { "x" : 435, "y" : 738, "width" : 43, "height" : 31 }, "textPosition" : { "x" : 439, "y" : 743 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 473, "y" : 743 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 473, "y" : 743 } } }, "connectors" : [ { "edgeId" : 137787, "type" : "INPUT", "segments" : [ { "from" : { "x" : 432, "y" : 755 }, "to" : { "x" : 375, "y" : 763 } } ], "stoichiometry" : { "value" : 1 } } ], "trivial" : true }, { "id" : 137789, "reactomeId" : 29360, "displayName" : "NAD+", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 462, "y" : 714 }, "minX" : 375, "maxX" : 490, "minY" : 698, "maxY" : 763, "prop" : { "x" : 436, "y" : 699, "width" : 53, "height" : 31 }, "textPosition" : { "x" : 440, "y" : 704 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 484, "y" : 704 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 484, "y" : 704 } } }, "connectors" : [ { "edgeId" : 137787, "type" : "INPUT", "segments" : [ { "from" : { "x" : 433, "y" : 728 }, "to" : { "x" : 375, "y" : 763 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 137794, "reactomeId" : 29356, "displayName" : "H2O", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 969, "y" : 337 }, "minX" : 943, "maxX" : 992, "minY" : 321, "maxY" : 372, "prop" : { "x" : 948, "y" : 322, "width" : 43, "height" : 31 }, "textPosition" : { "x" : 952, "y" : 327 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 986, "y" : 327 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 986, "y" : 327 } } }, "connectors" : [ { "edgeId" : 137792, "type" : "INPUT", "segments" : [ { "from" : { "x" : 957, "y" : 356 }, "to" : { "x" : 943, "y" : 372 } } ], "stoichiometry" : { "value" : 1 } } ], "trivial" : true }, { "id" : 137795, "reactomeId" : 73578, "displayName" : "R5P", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 948, "y" : 515 }, "minX" : 928, "maxX" : 969, "minY" : 467, "maxY" : 531, "prop" : { "x" : 928, "y" : 500, "width" : 40, "height" : 31 }, "textPosition" : { "x" : 932, "y" : 505 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 963, "y" : 505 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 963, "y" : 505 } } }, "connectors" : [ { "edgeId" : 137792, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 947, "y" : 497 }, "to" : { "x" : 945, "y" : 467 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 943, "y" : 490 }, "b" : { "x" : 947, "y" : 497 }, "c" : { "x" : 951, "y" : 490 }, "type" : "ARROW", "centre" : { "x" : 951, "y" : 490 } } } ] }, { "id" : 137793, "reactomeId" : 1131972, "displayName" : "ADP-D-ribose", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 870, "y" : 325 }, "minX" : 820, "maxX" : 943, "minY" : 309, "maxY" : 372, "prop" : { "x" : 820, "y" : 310, "width" : 100, "height" : 31 }, "textPosition" : { "x" : 825, "y" : 315 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 915, "y" : 315 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 915, "y" : 315 } } }, "connectors" : [ { "edgeId" : 137792, "type" : "INPUT", "segments" : [ { "from" : { "x" : 894, "y" : 344 }, "to" : { "x" : 943, "y" : 372 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 137798, "reactomeId" : 11019705, "displayName" : "NUDT5 dimer", "schemaClass" : "Complex", "renderableClass" : "Complex", "position" : { "x" : 1006, "y" : 415 }, "minX" : 952, "maxX" : 1040, "minY" : 392, "maxY" : 432, "prop" : { "x" : 978, "y" : 398, "width" : 56, "height" : 34 }, "textPosition" : { "x" : 979, "y" : 397 }, "bgColor" : { "r" : 204, "g" : 255, "b" : 255 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1034, "y" : 398 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1034, "y" : 398 } } }, "connectors" : [ { "edgeId" : 137792, "type" : "CATALYST", "segments" : [ { "from" : { "x" : 975, "y" : 413 }, "to" : { "x" : 960, "y" : 413 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "c" : { "x" : 956, "y" : 412 }, "r" : 4, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 956, "y" : 412 } } } ] }, { "id" : 137796, "reactomeId" : 76577, "displayName" : "AMP", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 847, "y" : 515 }, "minX" : 826, "maxX" : 945, "minY" : 467, "maxY" : 531, "prop" : { "x" : 826, "y" : 500, "width" : 42, "height" : 31 }, "textPosition" : { "x" : 830, "y" : 505 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 863, "y" : 505 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 863, "y" : 505 } } }, "connectors" : [ { "edgeId" : 137792, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 871, "y" : 504 }, "to" : { "x" : 945, "y" : 467 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 875, "y" : 497 }, "b" : { "x" : 871, "y" : 504 }, "c" : { "x" : 879, "y" : 504 }, "type" : "ARROW", "centre" : { "x" : 879, "y" : 504 } } } ] }, { "id" : 137797, "reactomeId" : 70106, "displayName" : "H+", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 895, "y" : 429 }, "minX" : 876, "maxX" : 945, "minY" : 412, "maxY" : 467, "prop" : { "x" : 876, "y" : 413, "width" : 39, "height" : 32 }, "textPosition" : { "x" : 882, "y" : 418 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 910, "y" : 418 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 910, "y" : 418 } } }, "connectors" : [ { "edgeId" : 137792, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 918, "y" : 443 }, "to" : { "x" : 945, "y" : 467 } } ], "stoichiometry" : { "value" : 2, "shape" : { "a" : { "x" : 925, "y" : 449 }, "b" : { "x" : 937, "y" : 461 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 931, "y" : 455 } } }, "endShape" : { "a" : { "x" : 926, "y" : 445 }, "b" : { "x" : 918, "y" : 443 }, "c" : { "x" : 921, "y" : 451 }, "type" : "ARROW", "centre" : { "x" : 921, "y" : 451 } } } ], "trivial" : true }, { "id" : 137802, "reactomeId" : 111294, "displayName" : "PPi", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 592, "y" : 521 }, "minX" : 519, "maxX" : 710, "minY" : 458, "maxY" : 537, "prop" : { "x" : 575, "y" : 506, "width" : 34, "height" : 31 }, "textPosition" : { "x" : 578, "y" : 511 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 604, "y" : 511 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 604, "y" : 511 } } }, "connectors" : [ { "edgeId" : 137799, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 572, "y" : 506 }, "to" : { "x" : 519, "y" : 458 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 564, "y" : 504 }, "b" : { "x" : 572, "y" : 506 }, "c" : { "x" : 570, "y" : 498 }, "type" : "ARROW", "centre" : { "x" : 570, "y" : 498 } } }, { "edgeId" : 137807, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 612, "y" : 515 }, "to" : { "x" : 710, "y" : 481 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 617, "y" : 509 }, "b" : { "x" : 612, "y" : 515 }, "c" : { "x" : 620, "y" : 517 }, "type" : "ARROW", "centre" : { "x" : 620, "y" : 517 } } }, { "edgeId" : 137810, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 612, "y" : 509 }, "to" : { "x" : 671, "y" : 469 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 615, "y" : 502 }, "b" : { "x" : 612, "y" : 509 }, "c" : { "x" : 620, "y" : 508 }, "type" : "ARROW", "centre" : { "x" : 620, "y" : 508 } } } ] }, { "id" : 137803, "reactomeId" : 29602, "displayName" : "IMP", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 518, "y" : 532 }, "minX" : 500, "maxX" : 538, "minY" : 458, "maxY" : 548, "prop" : { "x" : 500, "y" : 517, "width" : 37, "height" : 31 }, "textPosition" : { "x" : 504, "y" : 522 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 532, "y" : 522 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 532, "y" : 522 } } }, "connectors" : [ { "edgeId" : 137799, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 518, "y" : 514 }, "to" : { "x" : 519, "y" : 458 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 514, "y" : 507 }, "b" : { "x" : 518, "y" : 514 }, "c" : { "x" : 522, "y" : 507 }, "type" : "ARROW", "centre" : { "x" : 522, "y" : 507 } } } ] }, { "id" : 137800, "reactomeId" : 2509836, "displayName" : "ITP", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 510, "y" : 337 }, "minX" : 493, "maxX" : 529, "minY" : 321, "maxY" : 376, "prop" : { "x" : 493, "y" : 322, "width" : 35, "height" : 31 }, "textPosition" : { "x" : 497, "y" : 327 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 523, "y" : 327 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 523, "y" : 327 } } }, "connectors" : [ { "edgeId" : 137799, "type" : "INPUT", "segments" : [ { "from" : { "x" : 513, "y" : 356 }, "to" : { "x" : 519, "y" : 376 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 137801, "reactomeId" : 29356, "displayName" : "H2O", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 592, "y" : 340 }, "minX" : 519, "maxX" : 707, "minY" : 324, "maxY" : 387, "prop" : { "x" : 571, "y" : 325, "width" : 43, "height" : 31 }, "textPosition" : { "x" : 575, "y" : 330 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 609, "y" : 330 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 609, "y" : 330 } } }, "connectors" : [ { "edgeId" : 137799, "type" : "INPUT", "segments" : [ { "from" : { "x" : 568, "y" : 350 }, "to" : { "x" : 519, "y" : 376 } } ], "stoichiometry" : { "value" : 1 } }, { "edgeId" : 137807, "type" : "INPUT", "segments" : [ { "from" : { "x" : 617, "y" : 347 }, "to" : { "x" : 707, "y" : 382 } } ], "stoichiometry" : { "value" : 1 } }, { "edgeId" : 137810, "type" : "INPUT", "segments" : [ { "from" : { "x" : 617, "y" : 353 }, "to" : { "x" : 669, "y" : 387 } } ], "stoichiometry" : { "value" : 1 } } ], "trivial" : true }, { "id" : 137806, "reactomeId" : 29926, "displayName" : "Mg2+", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 592, "y" : 441 }, "minX" : 529, "maxX" : 699, "minY" : 412, "maxY" : 457, "prop" : { "x" : 566, "y" : 426, "width" : 52, "height" : 31 }, "textPosition" : { "x" : 570, "y" : 431 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 613, "y" : 431 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 613, "y" : 431 } } }, "connectors" : [ { "edgeId" : 137799, "type" : "ACTIVATOR", "segments" : [ { "from" : { "x" : 563, "y" : 433 }, "to" : { "x" : 529, "y" : 423 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 537, "y" : 421 }, "b" : { "x" : 529, "y" : 423 }, "c" : { "x" : 535, "y" : 429 }, "type" : "ARROW", "empty" : true, "centre" : { "x" : 535, "y" : 429 } } }, { "edgeId" : 137807, "type" : "ACTIVATOR", "segments" : [ { "from" : { "x" : 621, "y" : 434 }, "to" : { "x" : 699, "y" : 414 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 693, "y" : 420 }, "b" : { "x" : 699, "y" : 414 }, "c" : { "x" : 691, "y" : 412 }, "type" : "ARROW", "empty" : true, "centre" : { "x" : 691, "y" : 412 } } }, { "edgeId" : 137810, "type" : "ACTIVATOR", "segments" : [ { "from" : { "x" : 621, "y" : 442 }, "to" : { "x" : 661, "y" : 445 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 654, "y" : 448 }, "b" : { "x" : 661, "y" : 445 }, "c" : { "x" : 654, "y" : 440 }, "type" : "ARROW", "empty" : true, "centre" : { "x" : 654, "y" : 440 } } } ] }, { "id" : 137804, "reactomeId" : 70106, "displayName" : "H+", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 592, "y" : 482 }, "minX" : 519, "maxX" : 710, "minY" : 458, "maxY" : 498, "prop" : { "x" : 573, "y" : 466, "width" : 39, "height" : 32 }, "textPosition" : { "x" : 579, "y" : 471 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 607, "y" : 471 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 607, "y" : 471 } } }, "connectors" : [ { "edgeId" : 137799, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 570, "y" : 475 }, "to" : { "x" : 519, "y" : 458 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 562, "y" : 477 }, "b" : { "x" : 570, "y" : 475 }, "c" : { "x" : 565, "y" : 469 }, "type" : "ARROW", "centre" : { "x" : 565, "y" : 469 } } }, { "edgeId" : 137807, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 615, "y" : 481 }, "to" : { "x" : 710, "y" : 481 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 622, "y" : 477 }, "b" : { "x" : 615, "y" : 481 }, "c" : { "x" : 622, "y" : 485 }, "type" : "ARROW", "centre" : { "x" : 622, "y" : 485 } } }, { "edgeId" : 137810, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 615, "y" : 478 }, "to" : { "x" : 671, "y" : 469 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 621, "y" : 473 }, "b" : { "x" : 615, "y" : 478 }, "c" : { "x" : 622, "y" : 481 }, "type" : "ARROW", "centre" : { "x" : 622, "y" : 481 } } } ], "trivial" : true }, { "id" : 137805, "reactomeId" : 11019993, "displayName" : "ITPA dimer", "schemaClass" : "Complex", "renderableClass" : "Complex", "position" : { "x" : 592, "y" : 401 }, "minX" : 527, "maxX" : 700, "minY" : 384, "maxY" : 445, "prop" : { "x" : 556, "y" : 390, "width" : 73, "height" : 23 }, "textPosition" : { "x" : 556, "y" : 392 }, "bgColor" : { "r" : 204, "g" : 255, "b" : 255 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 629, "y" : 390 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 629, "y" : 390 } } }, "connectors" : [ { "edgeId" : 137799, "type" : "CATALYST", "segments" : [ { "from" : { "x" : 553, "y" : 411 }, "to" : { "x" : 535, "y" : 416 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "c" : { "x" : 531, "y" : 418 }, "r" : 4, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 531, "y" : 418 } } }, { "edgeId" : 137807, "type" : "CATALYST", "segments" : [ { "from" : { "x" : 632, "y" : 404 }, "to" : { "x" : 692, "y" : 410 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "c" : { "x" : 696, "y" : 411 }, "r" : 4, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 696, "y" : 411 } } }, { "edgeId" : 137810, "type" : "CATALYST", "segments" : [ { "from" : { "x" : 611, "y" : 416 }, "to" : { "x" : 656, "y" : 439 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "c" : { "x" : 659, "y" : 441 }, "r" : 4, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 659, "y" : 441 } } } ] }, { "id" : 137811, "reactomeId" : 2509835, "displayName" : "dITP", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 668, "y" : 335 }, "minX" : 647, "maxX" : 691, "minY" : 319, "maxY" : 387, "prop" : { "x" : 647, "y" : 320, "width" : 43, "height" : 31 }, "textPosition" : { "x" : 651, "y" : 325 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 685, "y" : 325 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 685, "y" : 325 } } }, "connectors" : [ { "edgeId" : 137810, "type" : "INPUT", "segments" : [ { "from" : { "x" : 668, "y" : 354 }, "to" : { "x" : 669, "y" : 387 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 137808, "reactomeId" : 2509848, "displayName" : "XTP", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 733, "y" : 336 }, "minX" : 707, "maxX" : 754, "minY" : 320, "maxY" : 382, "prop" : { "x" : 713, "y" : 321, "width" : 40, "height" : 31 }, "textPosition" : { "x" : 718, "y" : 326 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 748, "y" : 326 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 748, "y" : 326 } } }, "connectors" : [ { "edgeId" : 137807, "type" : "INPUT", "segments" : [ { "from" : { "x" : 724, "y" : 355 }, "to" : { "x" : 707, "y" : 382 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 137809, "reactomeId" : 111584, "displayName" : "XMP", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 741, "y" : 532 }, "minX" : 710, "maxX" : 763, "minY" : 481, "maxY" : 548, "prop" : { "x" : 720, "y" : 517, "width" : 42, "height" : 31 }, "textPosition" : { "x" : 724, "y" : 522 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 757, "y" : 522 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 757, "y" : 522 } } }, "connectors" : [ { "edgeId" : 137807, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 731, "y" : 514 }, "to" : { "x" : 710, "y" : 481 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 724, "y" : 510 }, "b" : { "x" : 731, "y" : 514 }, "c" : { "x" : 731, "y" : 506 }, "type" : "ARROW", "centre" : { "x" : 731, "y" : 506 } } } ] }, { "id" : 137814, "reactomeId" : 500430, "displayName" : "(d)Ura", "schemaClass" : "DefinedSet", "renderableClass" : "EntitySet", "position" : { "x" : 554, "y" : 868 }, "minX" : 532, "maxX" : 577, "minY" : 857, "maxY" : 919, "prop" : { "x" : 532, "y" : 857, "width" : 45, "height" : 23 }, "textPosition" : { "x" : 539, "y" : 851 }, "connectors" : [ { "edgeId" : 137813, "type" : "INPUT", "segments" : [ { "from" : { "x" : 553, "y" : 886 }, "to" : { "x" : 553, "y" : 919 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 137815, "reactomeId" : 29372, "displayName" : "Pi", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 606, "y" : 885 }, "minX" : 553, "maxX" : 621, "minY" : 869, "maxY" : 919, "prop" : { "x" : 593, "y" : 870, "width" : 27, "height" : 31 }, "textPosition" : { "x" : 597, "y" : 875 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 615, "y" : 875 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 615, "y" : 875 } } }, "connectors" : [ { "edgeId" : 137813, "type" : "INPUT", "segments" : [ { "from" : { "x" : 590, "y" : 893 }, "to" : { "x" : 553, "y" : 919 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 137812, "reactomeId" : 9731659, "displayName" : "dIMP", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 674, "y" : 532 }, "minX" : 648, "maxX" : 701, "minY" : 469, "maxY" : 548, "prop" : { "x" : 648, "y" : 516, "width" : 52, "height" : 32 }, "textPosition" : { "x" : 655, "y" : 521 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 695, "y" : 521 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 695, "y" : 521 } } }, "connectors" : [ { "edgeId" : 137810, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 673, "y" : 513 }, "to" : { "x" : 671, "y" : 469 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 669, "y" : 506 }, "b" : { "x" : 673, "y" : 513 }, "c" : { "x" : 677, "y" : 506 }, "type" : "ARROW", "centre" : { "x" : 677, "y" : 506 } } } ] }, { "id" : 137818, "reactomeId" : 11000795, "displayName" : "UPP1, UPP2", "schemaClass" : "DefinedSet", "renderableClass" : "EntitySet", "position" : { "x" : 625, "y" : 949 }, "minX" : 563, "maxX" : 664, "minY" : 938, "maxY" : 961, "prop" : { "x" : 587, "y" : 938, "width" : 77, "height" : 23 }, "textPosition" : { "x" : 601, "y" : 932 }, "connectors" : [ { "edgeId" : 137813, "type" : "CATALYST", "segments" : [ { "from" : { "x" : 581, "y" : 952 }, "to" : { "x" : 571, "y" : 954 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "c" : { "x" : 567, "y" : 954 }, "r" : 4, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 567, "y" : 954 } } } ] }, { "id" : 137816, "reactomeId" : 83962, "displayName" : "Ura", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 557, "y" : 1046 }, "minX" : 539, "maxX" : 577, "minY" : 981, "maxY" : 1062, "prop" : { "x" : 539, "y" : 1031, "width" : 37, "height" : 31 }, "textPosition" : { "x" : 542, "y" : 1036 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 571, "y" : 1036 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 571, "y" : 1036 } } }, "connectors" : [ { "edgeId" : 137813, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 556, "y" : 1028 }, "to" : { "x" : 556, "y" : 981 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 552, "y" : 1021 }, "b" : { "x" : 556, "y" : 1028 }, "c" : { "x" : 560, "y" : 1021 }, "type" : "ARROW", "centre" : { "x" : 560, "y" : 1021 } } } ] }, { "id" : 137817, "reactomeId" : 500244, "displayName" : "R1P, dRibP", "schemaClass" : "DefinedSet", "renderableClass" : "EntitySet", "position" : { "x" : 627, "y" : 1010 }, "minX" : 556, "maxX" : 664, "minY" : 981, "maxY" : 1022, "prop" : { "x" : 590, "y" : 999, "width" : 74, "height" : 23 }, "textPosition" : { "x" : 605, "y" : 993 }, "connectors" : [ { "edgeId" : 137813, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 598, "y" : 993 }, "to" : { "x" : 556, "y" : 981 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 590, "y" : 995 }, "b" : { "x" : 598, "y" : 993 }, "c" : { "x" : 592, "y" : 987 }, "type" : "ARROW", "centre" : { "x" : 592, "y" : 987 } } } ] }, { "id" : 137822, "reactomeId" : 83962, "displayName" : "Ura", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 1079, "y" : 649 }, "minX" : 1061, "maxX" : 1099, "minY" : 633, "maxY" : 708, "prop" : { "x" : 1061, "y" : 634, "width" : 37, "height" : 31 }, "textPosition" : { "x" : 1064, "y" : 639 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1093, "y" : 639 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1093, "y" : 639 } } }, "connectors" : [ { "edgeId" : 137819, "type" : "INPUT", "segments" : [ { "from" : { "x" : 1078, "y" : 668 }, "to" : { "x" : 1078, "y" : 708 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 137823, "reactomeId" : 73584, "displayName" : "5,6-Dihydrouracil", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 1079, "y" : 824 }, "minX" : 1019, "maxX" : 1140, "minY" : 773, "maxY" : 877, "prop" : { "x" : 1019, "y" : 809, "width" : 120, "height" : 31 }, "textPosition" : { "x" : 1022, "y" : 814 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1134, "y" : 814 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1134, "y" : 814 } } }, "connectors" : [ { "edgeId" : 137826, "type" : "INPUT", "segments" : [ { "from" : { "x" : 1078, "y" : 843 }, "to" : { "x" : 1077, "y" : 877 } } ], "stoichiometry" : { "value" : 1 } }, { "edgeId" : 137819, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 1078, "y" : 806 }, "to" : { "x" : 1078, "y" : 773 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 1074, "y" : 799 }, "b" : { "x" : 1078, "y" : 806 }, "c" : { "x" : 1082, "y" : 799 }, "type" : "ARROW", "centre" : { "x" : 1082, "y" : 799 } } } ] }, { "id" : 137820, "reactomeId" : 70106, "displayName" : "H+", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 1169, "y" : 705 }, "minX" : 1078, "maxX" : 1254, "minY" : 688, "maxY" : 721, "prop" : { "x" : 1150, "y" : 689, "width" : 39, "height" : 32 }, "textPosition" : { "x" : 1156, "y" : 694 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1184, "y" : 694 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1184, "y" : 694 } } }, "connectors" : [ { "edgeId" : 137837, "type" : "INPUT", "segments" : [ { "from" : { "x" : 1192, "y" : 704 }, "to" : { "x" : 1254, "y" : 703 } } ], "stoichiometry" : { "value" : 1 } }, { "edgeId" : 137819, "type" : "INPUT", "segments" : [ { "from" : { "x" : 1147, "y" : 705 }, "to" : { "x" : 1078, "y" : 708 } } ], "stoichiometry" : { "value" : 1 } } ], "trivial" : true }, { "id" : 137821, "reactomeId" : 29364, "displayName" : "NADPH", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 1169, "y" : 662 }, "minX" : 1078, "maxX" : 1254, "minY" : 646, "maxY" : 708, "prop" : { "x" : 1140, "y" : 647, "width" : 59, "height" : 31 }, "textPosition" : { "x" : 1144, "y" : 652 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1194, "y" : 652 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1194, "y" : 652 } } }, "connectors" : [ { "edgeId" : 137837, "type" : "INPUT", "segments" : [ { "from" : { "x" : 1202, "y" : 676 }, "to" : { "x" : 1254, "y" : 703 } } ], "stoichiometry" : { "value" : 1 } }, { "edgeId" : 137819, "type" : "INPUT", "segments" : [ { "from" : { "x" : 1137, "y" : 676 }, "to" : { "x" : 1078, "y" : 708 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 137827, "reactomeId" : 29356, "displayName" : "H2O", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 1169, "y" : 853 }, "minX" : 1077, "maxX" : 1254, "minY" : 837, "maxY" : 882, "prop" : { "x" : 1148, "y" : 838, "width" : 43, "height" : 31 }, "textPosition" : { "x" : 1152, "y" : 843 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1186, "y" : 843 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1186, "y" : 843 } } }, "connectors" : [ { "edgeId" : 137826, "type" : "INPUT", "segments" : [ { "from" : { "x" : 1145, "y" : 858 }, "to" : { "x" : 1077, "y" : 877 } } ], "stoichiometry" : { "value" : 1 } }, { "edgeId" : 137840, "type" : "INPUT", "segments" : [ { "from" : { "x" : 1194, "y" : 860 }, "to" : { "x" : 1254, "y" : 882 } } ], "stoichiometry" : { "value" : 1 } } ], "trivial" : true }, { "id" : 137824, "reactomeId" : 29366, "displayName" : "NADP+", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 1169, "y" : 795 }, "minX" : 1078, "maxX" : 1256, "minY" : 773, "maxY" : 811, "prop" : { "x" : 1139, "y" : 780, "width" : 60, "height" : 31 }, "textPosition" : { "x" : 1143, "y" : 785 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1194, "y" : 785 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1194, "y" : 785 } } }, "connectors" : [ { "edgeId" : 137837, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 1202, "y" : 791 }, "to" : { "x" : 1256, "y" : 784 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 1208, "y" : 786 }, "b" : { "x" : 1202, "y" : 791 }, "c" : { "x" : 1209, "y" : 794 }, "type" : "ARROW", "centre" : { "x" : 1209, "y" : 794 } } }, { "edgeId" : 137819, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 1136, "y" : 787 }, "to" : { "x" : 1078, "y" : 773 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 1128, "y" : 789 }, "b" : { "x" : 1136, "y" : 787 }, "c" : { "x" : 1130, "y" : 781 }, "type" : "ARROW", "centre" : { "x" : 1130, "y" : 781 } } } ] }, { "id" : 137825, "reactomeId" : 11000031, "displayName" : "DPYD dimer", "schemaClass" : "Complex", "renderableClass" : "Complex", "position" : { "x" : 1169, "y" : 751 }, "minX" : 1087, "maxX" : 1247, "minY" : 734, "maxY" : 763, "prop" : { "x" : 1130, "y" : 740, "width" : 79, "height" : 23 }, "textPosition" : { "x" : 1147, "y" : 728 }, "bgColor" : { "r" : 204, "g" : 255, "b" : 255 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1209, "y" : 740 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1209, "y" : 740 } } }, "connectors" : [ { "edgeId" : 137837, "type" : "CATALYST", "segments" : [ { "from" : { "x" : 1212, "y" : 751 }, "to" : { "x" : 1239, "y" : 752 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "c" : { "x" : 1243, "y" : 752 }, "r" : 4, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1243, "y" : 752 } } }, { "edgeId" : 137819, "type" : "CATALYST", "segments" : [ { "from" : { "x" : 1127, "y" : 747 }, "to" : { "x" : 1095, "y" : 744 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "c" : { "x" : 1091, "y" : 743 }, "r" : 4, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1091, "y" : 743 } } } ] }, { "id" : 137830, "reactomeId" : 11000041, "displayName" : "DPYS tetramer", "schemaClass" : "Complex", "renderableClass" : "Complex", "position" : { "x" : 1169, "y" : 901 }, "minX" : 1087, "maxX" : 1246, "minY" : 884, "maxY" : 913, "prop" : { "x" : 1123, "y" : 890, "width" : 92, "height" : 23 }, "textPosition" : { "x" : 1137, "y" : 878 }, "bgColor" : { "r" : 204, "g" : 255, "b" : 255 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1215, "y" : 890 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1215, "y" : 890 } } }, "connectors" : [ { "edgeId" : 137826, "type" : "CATALYST", "segments" : [ { "from" : { "x" : 1120, "y" : 903 }, "to" : { "x" : 1095, "y" : 904 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "c" : { "x" : 1091, "y" : 904 }, "r" : 4, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1091, "y" : 904 } } }, { "edgeId" : 137840, "type" : "CATALYST", "segments" : [ { "from" : { "x" : 1218, "y" : 904 }, "to" : { "x" : 1238, "y" : 906 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "c" : { "x" : 1242, "y" : 906 }, "r" : 4, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1242, "y" : 906 } } } ] }, { "id" : 137828, "reactomeId" : 73588, "displayName" : "UPROP", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 1079, "y" : 961 }, "minX" : 1051, "maxX" : 1108, "minY" : 924, "maxY" : 1016, "prop" : { "x" : 1051, "y" : 946, "width" : 56, "height" : 31 }, "textPosition" : { "x" : 1054, "y" : 951 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1102, "y" : 951 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1102, "y" : 951 } } }, "connectors" : [ { "edgeId" : 137826, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 1079, "y" : 943 }, "to" : { "x" : 1080, "y" : 924 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 1075, "y" : 936 }, "b" : { "x" : 1079, "y" : 943 }, "c" : { "x" : 1083, "y" : 936 }, "type" : "ARROW", "centre" : { "x" : 1083, "y" : 936 } } }, { "edgeId" : 137831, "type" : "INPUT", "segments" : [ { "from" : { "x" : 1079, "y" : 980 }, "to" : { "x" : 1079, "y" : 1016 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 137829, "reactomeId" : 70106, "displayName" : "H+", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 1169, "y" : 949 }, "minX" : 1079, "maxX" : 1253, "minY" : 924, "maxY" : 1016, "prop" : { "x" : 1150, "y" : 933, "width" : 39, "height" : 32 }, "textPosition" : { "x" : 1156, "y" : 938 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1184, "y" : 938 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1184, "y" : 938 } } }, "connectors" : [ { "edgeId" : 137826, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 1147, "y" : 943 }, "to" : { "x" : 1080, "y" : 924 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 1139, "y" : 945 }, "b" : { "x" : 1147, "y" : 943 }, "c" : { "x" : 1141, "y" : 937 }, "type" : "ARROW", "centre" : { "x" : 1141, "y" : 937 } } }, { "edgeId" : 137831, "type" : "INPUT", "segments" : [ { "from" : { "x" : 1147, "y" : 963 }, "to" : { "x" : 1079, "y" : 1016 } } ], "stoichiometry" : { "value" : 2, "shape" : { "a" : { "x" : 1107, "y" : 983 }, "b" : { "x" : 1119, "y" : 995 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 1113, "y" : 989 } } } }, { "edgeId" : 137842, "type" : "INPUT", "segments" : [ { "from" : { "x" : 1192, "y" : 963 }, "to" : { "x" : 1253, "y" : 1013 } } ], "stoichiometry" : { "value" : 2, "shape" : { "a" : { "x" : 1216, "y" : 982 }, "b" : { "x" : 1228, "y" : 994 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 1222, "y" : 988 } } } }, { "edgeId" : 137840, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 1192, "y" : 943 }, "to" : { "x" : 1253, "y" : 926 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 1198, "y" : 937 }, "b" : { "x" : 1192, "y" : 943 }, "c" : { "x" : 1200, "y" : 945 }, "type" : "ARROW", "centre" : { "x" : 1200, "y" : 945 } } } ], "trivial" : true }, { "id" : 137834, "reactomeId" : 73590, "displayName" : "b-Ala", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 1358, "y" : 1105 }, "minX" : 1081, "maxX" : 1384, "minY" : 1077, "maxY" : 1121, "prop" : { "x" : 1333, "y" : 1090, "width" : 50, "height" : 31 }, "textPosition" : { "x" : 1338, "y" : 1095 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1378, "y" : 1095 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1378, "y" : 1095 } } }, "connectors" : [ { "edgeId" : 137831, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 1330, "y" : 1102 }, "to" : { "x" : 1081, "y" : 1077 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 1323, "y" : 1105 }, "b" : { "x" : 1330, "y" : 1102 }, "c" : { "x" : 1324, "y" : 1097 }, "type" : "ARROW", "centre" : { "x" : 1324, "y" : 1097 } } } ] }, { "id" : 137835, "reactomeId" : 31633, "displayName" : "NH4+", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 1079, "y" : 1136 }, "minX" : 1053, "maxX" : 1255, "minY" : 1077, "maxY" : 1152, "prop" : { "x" : 1053, "y" : 1121, "width" : 53, "height" : 31 }, "textPosition" : { "x" : 1057, "y" : 1126 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1101, "y" : 1126 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1101, "y" : 1126 } } }, "connectors" : [ { "edgeId" : 137831, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 1079, "y" : 1118 }, "to" : { "x" : 1081, "y" : 1077 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 1075, "y" : 1111 }, "b" : { "x" : 1079, "y" : 1118 }, "c" : { "x" : 1083, "y" : 1111 }, "type" : "ARROW", "centre" : { "x" : 1083, "y" : 1111 } } }, { "edgeId" : 137842, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 1109, "y" : 1127 }, "to" : { "x" : 1255, "y" : 1079 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 1114, "y" : 1121 }, "b" : { "x" : 1109, "y" : 1127 }, "c" : { "x" : 1117, "y" : 1129 }, "type" : "ARROW", "centre" : { "x" : 1117, "y" : 1129 } } } ] }, { "id" : 137832, "reactomeId" : 29356, "displayName" : "H2O", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 1169, "y" : 999 }, "minX" : 1079, "maxX" : 1253, "minY" : 983, "maxY" : 1016, "prop" : { "x" : 1148, "y" : 984, "width" : 43, "height" : 31 }, "textPosition" : { "x" : 1152, "y" : 989 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1186, "y" : 989 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1186, "y" : 989 } } }, "connectors" : [ { "edgeId" : 137831, "type" : "INPUT", "segments" : [ { "from" : { "x" : 1145, "y" : 1003 }, "to" : { "x" : 1079, "y" : 1016 } } ], "stoichiometry" : { "value" : 1 } }, { "edgeId" : 137842, "type" : "INPUT", "segments" : [ { "from" : { "x" : 1194, "y" : 1002 }, "to" : { "x" : 1253, "y" : 1013 } } ], "stoichiometry" : { "value" : 1 } } ], "trivial" : true }, { "id" : 137833, "reactomeId" : 113528, "displayName" : "CO2", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 1194, "y" : 1134 }, "minX" : 1081, "maxX" : 1255, "minY" : 1077, "maxY" : 1150, "prop" : { "x" : 1173, "y" : 1119, "width" : 42, "height" : 31 }, "textPosition" : { "x" : 1177, "y" : 1124 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1210, "y" : 1124 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1210, "y" : 1124 } } }, "connectors" : [ { "edgeId" : 137831, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 1170, "y" : 1123 }, "to" : { "x" : 1081, "y" : 1077 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 1162, "y" : 1123 }, "b" : { "x" : 1170, "y" : 1123 }, "c" : { "x" : 1166, "y" : 1116 }, "type" : "ARROW", "centre" : { "x" : 1166, "y" : 1116 } } }, { "edgeId" : 137842, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 1211, "y" : 1116 }, "to" : { "x" : 1255, "y" : 1079 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 1214, "y" : 1108 }, "b" : { "x" : 1211, "y" : 1116 }, "c" : { "x" : 1219, "y" : 1115 }, "type" : "ARROW", "centre" : { "x" : 1219, "y" : 1115 } } } ], "trivial" : true }, { "id" : 137838, "reactomeId" : 83960, "displayName" : "Thy", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 1252, "y" : 655 }, "minX" : 1233, "maxX" : 1272, "minY" : 639, "maxY" : 703, "prop" : { "x" : 1233, "y" : 640, "width" : 38, "height" : 31 }, "textPosition" : { "x" : 1237, "y" : 645 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1266, "y" : 645 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1266, "y" : 645 } } }, "connectors" : [ { "edgeId" : 137837, "type" : "INPUT", "segments" : [ { "from" : { "x" : 1252, "y" : 674 }, "to" : { "x" : 1254, "y" : 703 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 137839, "reactomeId" : 73541, "displayName" : "5,6-Dihydrothymine", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 1254, "y" : 835 }, "minX" : 1214, "maxX" : 1295, "minY" : 784, "maxY" : 882, "prop" : { "x" : 1214, "y" : 812, "width" : 80, "height" : 47 }, "textPosition" : { "x" : 1217, "y" : 811 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1289, "y" : 817 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1289, "y" : 817 } } }, "connectors" : [ { "edgeId" : 137837, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 1254, "y" : 809 }, "to" : { "x" : 1256, "y" : 784 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 1251, "y" : 802 }, "b" : { "x" : 1254, "y" : 809 }, "c" : { "x" : 1259, "y" : 802 }, "type" : "ARROW", "centre" : { "x" : 1259, "y" : 802 } } }, { "edgeId" : 137840, "type" : "INPUT", "segments" : [ { "from" : { "x" : 1254, "y" : 862 }, "to" : { "x" : 1254, "y" : 882 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 137836, "reactomeId" : 11000051, "displayName" : "UPB1:Zn2+", "schemaClass" : "Complex", "renderableClass" : "Complex", "position" : { "x" : 1169, "y" : 1042 }, "minX" : 1087, "maxX" : 1247, "minY" : 1025, "maxY" : 1054, "prop" : { "x" : 1132, "y" : 1031, "width" : 75, "height" : 23 }, "textPosition" : { "x" : 1147, "y" : 1019 }, "bgColor" : { "r" : 204, "g" : 255, "b" : 255 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1207, "y" : 1031 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1207, "y" : 1031 } } }, "connectors" : [ { "edgeId" : 137831, "type" : "CATALYST", "segments" : [ { "from" : { "x" : 1129, "y" : 1044 }, "to" : { "x" : 1095, "y" : 1046 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "c" : { "x" : 1091, "y" : 1046 }, "r" : 4, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1091, "y" : 1046 } } }, { "edgeId" : 137842, "type" : "CATALYST", "segments" : [ { "from" : { "x" : 1210, "y" : 1043 }, "to" : { "x" : 1239, "y" : 1045 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "c" : { "x" : 1243, "y" : 1045 }, "r" : 4, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1243, "y" : 1045 } } } ] }, { "id" : 137843, "reactomeId" : 73619, "displayName" : "3AIB", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 1496, "y" : 1072 }, "minX" : 1255, "maxX" : 1519, "minY" : 1056, "maxY" : 1088, "prop" : { "x" : 1475, "y" : 1057, "width" : 43, "height" : 31 }, "textPosition" : { "x" : 1479, "y" : 1062 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1513, "y" : 1062 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1513, "y" : 1062 } } }, "connectors" : [ { "edgeId" : 137842, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 1472, "y" : 1072 }, "to" : { "x" : 1255, "y" : 1079 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 1465, "y" : 1076 }, "b" : { "x" : 1472, "y" : 1072 }, "c" : { "x" : 1465, "y" : 1068 }, "type" : "ARROW", "centre" : { "x" : 1465, "y" : 1068 } } } ] }, { "id" : 137841, "reactomeId" : 73617, "displayName" : "UIBA", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 1253, "y" : 962 }, "minX" : 1232, "maxX" : 1276, "minY" : 926, "maxY" : 1013, "prop" : { "x" : 1232, "y" : 947, "width" : 43, "height" : 31 }, "textPosition" : { "x" : 1235, "y" : 952 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1270, "y" : 952 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1270, "y" : 952 } } }, "connectors" : [ { "edgeId" : 137842, "type" : "INPUT", "segments" : [ { "from" : { "x" : 1253, "y" : 981 }, "to" : { "x" : 1253, "y" : 1013 } } ], "stoichiometry" : { "value" : 1 } }, { "edgeId" : 137840, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 1253, "y" : 944 }, "to" : { "x" : 1253, "y" : 926 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 1249, "y" : 937 }, "b" : { "x" : 1253, "y" : 944 }, "c" : { "x" : 1257, "y" : 937 }, "type" : "ARROW", "centre" : { "x" : 1257, "y" : 937 } } } ] }, { "id" : 137972, "reactomeId" : 11048948, "displayName" : "Pentose phosphate pathway", "schemaClass" : "Pathway", "renderableClass" : "EncapsulatedNode", "position" : { "x" : 75, "y" : 833 }, "minX" : 30, "maxX" : 120, "minY" : 798, "maxY" : 869, "prop" : { "x" : 30, "y" : 798, "width" : 90, "height" : 71 }, "textPosition" : { "x" : 31, "y" : 805 }, "connectors" : [ ] } ], "edges" : [ { "id" : 137826, "reactomeId" : 11000044, "displayName" : "conversion of 5,6-dihydrouracil to 3-ureidopropionate", "schemaClass" : "Reaction", "renderableClass" : "Reaction", "position" : { "x" : 1079, "y" : 905 }, "minX" : 1073, "maxX" : 1085, "minY" : 877, "maxY" : 924, "reactionType" : "transition", "segments" : [ { "from" : { "x" : 1077, "y" : 877 }, "to" : { "x" : 1079, "y" : 905 } }, { "from" : { "x" : 1079, "y" : 905 }, "to" : { "x" : 1080, "y" : 924 } } ], "reactionShape" : { "a" : { "x" : 1073, "y" : 899 }, "b" : { "x" : 1085, "y" : 911 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 1079, "y" : 905 } }, "inputs" : [ { "id" : 137823, "points" : [ { "x" : 1078, "y" : 843 } ] }, { "id" : 137827, "points" : [ { "x" : 1145, "y" : 858 } ] } ], "outputs" : [ { "id" : 137828, "points" : [ { "x" : 1079, "y" : 943 } ] }, { "id" : 137829, "points" : [ { "x" : 1147, "y" : 943 } ] } ], "catalysts" : [ { "id" : 137830, "points" : [ { "x" : 1120, "y" : 903 } ] } ] }, { "id" : 137792, "reactomeId" : 11019708, "displayName" : "Cytosolic NUDT5 hydrolyses ADP-ribose to R5P and AMP", "schemaClass" : "Reaction", "renderableClass" : "Reaction", "position" : { "x" : 944, "y" : 412 }, "minX" : 938, "maxX" : 950, "minY" : 372, "maxY" : 467, "reactionType" : "transition", "segments" : [ { "from" : { "x" : 943, "y" : 372 }, "to" : { "x" : 944, "y" : 412 } }, { "from" : { "x" : 944, "y" : 412 }, "to" : { "x" : 945, "y" : 467 } } ], "reactionShape" : { "a" : { "x" : 938, "y" : 406 }, "b" : { "x" : 950, "y" : 418 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 944, "y" : 412 } }, "inputs" : [ { "id" : 137793, "points" : [ { "x" : 894, "y" : 344 } ] }, { "id" : 137794, "points" : [ { "x" : 957, "y" : 356 } ] } ], "outputs" : [ { "id" : 137795, "points" : [ { "x" : 947, "y" : 497 } ] }, { "id" : 137796, "points" : [ { "x" : 871, "y" : 504 } ] }, { "id" : 137797, "points" : [ { "x" : 918, "y" : 443 } ], "stoichiometry" : 2 } ], "catalysts" : [ { "id" : 137798, "points" : [ { "x" : 975, "y" : 413 } ] } ] }, { "id" : 137831, "reactomeId" : 11000054, "displayName" : "conversion of 3-ureidopropionate to beta-alanine", "schemaClass" : "Reaction", "renderableClass" : "Reaction", "position" : { "x" : 1079, "y" : 1047 }, "minX" : 1073, "maxX" : 1085, "minY" : 1016, "maxY" : 1077, "reactionType" : "transition", "segments" : [ { "from" : { "x" : 1079, "y" : 1016 }, "to" : { "x" : 1079, "y" : 1047 } }, { "from" : { "x" : 1079, "y" : 1047 }, "to" : { "x" : 1081, "y" : 1077 } } ], "reactionShape" : { "a" : { "x" : 1073, "y" : 1041 }, "b" : { "x" : 1085, "y" : 1053 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 1079, "y" : 1047 } }, "inputs" : [ { "id" : 137828, "points" : [ { "x" : 1079, "y" : 980 } ] }, { "id" : 137832, "points" : [ { "x" : 1145, "y" : 1003 } ] }, { "id" : 137829, "points" : [ { "x" : 1147, "y" : 963 } ], "stoichiometry" : 2 } ], "outputs" : [ { "id" : 137833, "points" : [ { "x" : 1170, "y" : 1123 } ] }, { "id" : 137834, "points" : [ { "x" : 1330, "y" : 1102 } ] }, { "id" : 137835, "points" : [ { "x" : 1079, "y" : 1118 } ] } ], "catalysts" : [ { "id" : 137836, "points" : [ { "x" : 1129, "y" : 1044 } ] } ] }, { "id" : 137799, "reactomeId" : 11019996, "displayName" : "ITPA hydrolyses ITP to IMP", "schemaClass" : "Reaction", "renderableClass" : "Reaction", "position" : { "x" : 520, "y" : 421 }, "minX" : 514, "maxX" : 526, "minY" : 376, "maxY" : 458, "reactionType" : "transition", "segments" : [ { "from" : { "x" : 519, "y" : 376 }, "to" : { "x" : 520, "y" : 421 } }, { "from" : { "x" : 520, "y" : 421 }, "to" : { "x" : 519, "y" : 458 } } ], "reactionShape" : { "a" : { "x" : 514, "y" : 415 }, "b" : { "x" : 526, "y" : 427 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 520, "y" : 421 } }, "inputs" : [ { "id" : 137800, "points" : [ { "x" : 513, "y" : 356 } ] }, { "id" : 137801, "points" : [ { "x" : 568, "y" : 350 } ] } ], "outputs" : [ { "id" : 137802, "points" : [ { "x" : 572, "y" : 506 } ] }, { "id" : 137803, "points" : [ { "x" : 518, "y" : 514 } ] }, { "id" : 137804, "points" : [ { "x" : 570, "y" : 475 } ] } ], "catalysts" : [ { "id" : 137805, "points" : [ { "x" : 553, "y" : 411 } ] } ], "activators" : [ { "id" : 137806, "points" : [ { "x" : 563, "y" : 433 } ] } ] }, { "id" : 137764, "reactomeId" : 11000781, "displayName" : "Guanine + H2O => Xanthine + NH4+", "schemaClass" : "Reaction", "renderableClass" : "Reaction", "position" : { "x" : 191, "y" : 678 }, "minX" : 185, "maxX" : 197, "minY" : 638, "maxY" : 711, "reactionType" : "transition", "segments" : [ { "from" : { "x" : 190, "y" : 638 }, "to" : { "x" : 191, "y" : 678 } }, { "from" : { "x" : 191, "y" : 678 }, "to" : { "x" : 191, "y" : 711 } } ], "reactionShape" : { "a" : { "x" : 185, "y" : 672 }, "b" : { "x" : 197, "y" : 684 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 191, "y" : 678 } }, "inputs" : [ { "id" : 137765, "points" : [ { "x" : 169, "y" : 627 } ] }, { "id" : 137766, "points" : [ { "x" : 189, "y" : 598 } ] }, { "id" : 137767, "points" : [ { "x" : 206, "y" : 627 } ] } ], "outputs" : [ { "id" : 137768, "points" : [ { "x" : 323, "y" : 718 } ] }, { "id" : 137769, "points" : [ { "x" : 149, "y" : 734 } ] } ], "catalysts" : [ { "id" : 137770, "points" : [ { "x" : 142, "y" : 678 } ] } ] }, { "id" : 137771, "reactomeId" : 11000761, "displayName" : "XDH oxidizes hypoxanthine to form xanthine", "schemaClass" : "Reaction", "renderableClass" : "Reaction", "position" : { "x" : 323, "y" : 627 }, "minX" : 317, "maxX" : 329, "minY" : 604, "maxY" : 658, "reactionType" : "transition", "segments" : [ { "from" : { "x" : 322, "y" : 604 }, "to" : { "x" : 323, "y" : 627 } }, { "from" : { "x" : 323, "y" : 627 }, "to" : { "x" : 322, "y" : 658 } } ], "reactionShape" : { "a" : { "x" : 317, "y" : 621 }, "b" : { "x" : 329, "y" : 633 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 323, "y" : 627 } }, "inputs" : [ { "id" : 137772, "points" : [ { "x" : 340, "y" : 559 } ] }, { "id" : 137773, "points" : [ { "x" : 301, "y" : 600 } ] }, { "id" : 137774, "points" : [ { "x" : 300, "y" : 579 } ] } ], "outputs" : [ { "id" : 137768, "points" : [ { "x" : 340, "y" : 702 } ] }, { "id" : 137775, "points" : [ { "x" : 307, "y" : 665 } ] } ], "catalysts" : [ { "id" : 137776, "points" : [ { "x" : 467, "y" : 631 } ] } ] }, { "id" : 137807, "reactomeId" : 11019999, "displayName" : "ITPA hydrolyses XTP to XMP", "schemaClass" : "Reaction", "renderableClass" : "Reaction", "position" : { "x" : 708, "y" : 412 }, "minX" : 702, "maxX" : 714, "minY" : 382, "maxY" : 481, "reactionType" : "transition", "segments" : [ { "from" : { "x" : 707, "y" : 382 }, "to" : { "x" : 708, "y" : 412 } }, { "from" : { "x" : 708, "y" : 412 }, "to" : { "x" : 710, "y" : 481 } } ], "reactionShape" : { "a" : { "x" : 702, "y" : 406 }, "b" : { "x" : 714, "y" : 418 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 708, "y" : 412 } }, "inputs" : [ { "id" : 137808, "points" : [ { "x" : 724, "y" : 355 } ] }, { "id" : 137801, "points" : [ { "x" : 617, "y" : 347 } ] } ], "outputs" : [ { "id" : 137809, "points" : [ { "x" : 731, "y" : 514 } ] }, { "id" : 137804, "points" : [ { "x" : 615, "y" : 481 } ] }, { "id" : 137802, "points" : [ { "x" : 612, "y" : 515 } ] } ], "catalysts" : [ { "id" : 137805, "points" : [ { "x" : 632, "y" : 404 } ] } ], "activators" : [ { "id" : 137806, "points" : [ { "x" : 621, "y" : 434 } ] } ] }, { "id" : 137837, "reactomeId" : 11000086, "displayName" : "reduction of thymine to form 5,6-Dihydrothymine", "schemaClass" : "Reaction", "renderableClass" : "Reaction", "position" : { "x" : 1255, "y" : 752 }, "minX" : 1249, "maxX" : 1261, "minY" : 703, "maxY" : 784, "reactionType" : "transition", "segments" : [ { "from" : { "x" : 1254, "y" : 703 }, "to" : { "x" : 1255, "y" : 752 } }, { "from" : { "x" : 1255, "y" : 752 }, "to" : { "x" : 1256, "y" : 784 } } ], "reactionShape" : { "a" : { "x" : 1249, "y" : 746 }, "b" : { "x" : 1261, "y" : 758 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 1255, "y" : 752 } }, "inputs" : [ { "id" : 137820, "points" : [ { "x" : 1192, "y" : 704 } ] }, { "id" : 137838, "points" : [ { "x" : 1252, "y" : 674 } ] }, { "id" : 137821, "points" : [ { "x" : 1202, "y" : 676 } ] } ], "outputs" : [ { "id" : 137839, "points" : [ { "x" : 1254, "y" : 809 } ] }, { "id" : 137824, "points" : [ { "x" : 1202, "y" : 791 } ] } ], "catalysts" : [ { "id" : 137825, "points" : [ { "x" : 1212, "y" : 751 } ] } ] }, { "id" : 137810, "reactomeId" : 11020002, "displayName" : "ITPA hydrolyses dITP to dIMP", "schemaClass" : "Reaction", "renderableClass" : "Reaction", "position" : { "x" : 670, "y" : 446 }, "minX" : 664, "maxX" : 676, "minY" : 387, "maxY" : 469, "reactionType" : "transition", "segments" : [ { "from" : { "x" : 669, "y" : 387 }, "to" : { "x" : 670, "y" : 446 } }, { "from" : { "x" : 670, "y" : 446 }, "to" : { "x" : 671, "y" : 469 } } ], "reactionShape" : { "a" : { "x" : 664, "y" : 440 }, "b" : { "x" : 676, "y" : 452 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 670, "y" : 446 } }, "inputs" : [ { "id" : 137811, "points" : [ { "x" : 668, "y" : 354 } ] }, { "id" : 137801, "points" : [ { "x" : 617, "y" : 353 } ] } ], "outputs" : [ { "id" : 137802, "points" : [ { "x" : 612, "y" : 509 } ] }, { "id" : 137812, "points" : [ { "x" : 673, "y" : 513 } ] }, { "id" : 137804, "points" : [ { "x" : 615, "y" : 478 } ] } ], "catalysts" : [ { "id" : 137805, "points" : [ { "x" : 611, "y" : 416 } ] } ], "activators" : [ { "id" : 137806, "points" : [ { "x" : 621, "y" : 442 } ] } ] }, { "id" : 137842, "reactomeId" : 11000090, "displayName" : "conversion of 3-Ureidoiosbutyrate to 3-Aminoisobutyrate", "schemaClass" : "Reaction", "renderableClass" : "Reaction", "position" : { "x" : 1255, "y" : 1046 }, "minX" : 1249, "maxX" : 1261, "minY" : 1013, "maxY" : 1079, "reactionType" : "transition", "segments" : [ { "from" : { "x" : 1253, "y" : 1013 }, "to" : { "x" : 1255, "y" : 1046 } }, { "from" : { "x" : 1255, "y" : 1046 }, "to" : { "x" : 1255, "y" : 1079 } } ], "reactionShape" : { "a" : { "x" : 1249, "y" : 1040 }, "b" : { "x" : 1261, "y" : 1052 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 1255, "y" : 1046 } }, "inputs" : [ { "id" : 137841, "points" : [ { "x" : 1253, "y" : 981 } ] }, { "id" : 137829, "points" : [ { "x" : 1192, "y" : 963 } ], "stoichiometry" : 2 }, { "id" : 137832, "points" : [ { "x" : 1194, "y" : 1002 } ] } ], "outputs" : [ { "id" : 137833, "points" : [ { "x" : 1211, "y" : 1116 } ] }, { "id" : 137843, "points" : [ { "x" : 1472, "y" : 1072 } ] }, { "id" : 137835, "points" : [ { "x" : 1109, "y" : 1127 } ] } ], "catalysts" : [ { "id" : 137836, "points" : [ { "x" : 1210, "y" : 1043 } ] } ] }, { "id" : 137840, "reactomeId" : 11000088, "displayName" : "conversion of 5,6-Dihydrothymine to 3-Ureidoisobutyrate", "schemaClass" : "Reaction", "renderableClass" : "Reaction", "position" : { "x" : 1254, "y" : 907 }, "minX" : 1248, "maxX" : 1260, "minY" : 882, "maxY" : 926, "reactionType" : "transition", "segments" : [ { "from" : { "x" : 1254, "y" : 882 }, "to" : { "x" : 1254, "y" : 907 } }, { "from" : { "x" : 1254, "y" : 907 }, "to" : { "x" : 1253, "y" : 926 } } ], "reactionShape" : { "a" : { "x" : 1248, "y" : 901 }, "b" : { "x" : 1260, "y" : 913 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 1254, "y" : 907 } }, "inputs" : [ { "id" : 137839, "points" : [ { "x" : 1254, "y" : 862 } ] }, { "id" : 137827, "points" : [ { "x" : 1194, "y" : 860 } ] } ], "outputs" : [ { "id" : 137841, "points" : [ { "x" : 1253, "y" : 944 } ] }, { "id" : 137829, "points" : [ { "x" : 1192, "y" : 943 } ] } ], "catalysts" : [ { "id" : 137830, "points" : [ { "x" : 1218, "y" : 904 } ] } ] }, { "id" : 137777, "reactomeId" : 11045970, "displayName" : "XDH dehydrogenates hypoxanthine to form xanthine", "schemaClass" : "Reaction", "renderableClass" : "Reaction", "position" : { "x" : 376, "y" : 642 }, "minX" : 370, "maxX" : 382, "minY" : 595, "maxY" : 675, "reactionType" : "transition", "segments" : [ { "from" : { "x" : 375, "y" : 595 }, "to" : { "x" : 376, "y" : 642 } }, { "from" : { "x" : 376, "y" : 642 }, "to" : { "x" : 376, "y" : 675 } } ], "reactionShape" : { "a" : { "x" : 370, "y" : 636 }, "b" : { "x" : 382, "y" : 648 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 376, "y" : 642 } }, "inputs" : [ { "id" : 137772, "points" : [ { "x" : 354, "y" : 559 } ] }, { "id" : 137778, "points" : [ { "x" : 401, "y" : 561 } ] }, { "id" : 137779, "points" : [ { "x" : 426, "y" : 587 } ] } ], "outputs" : [ { "id" : 137768, "points" : [ { "x" : 356, "y" : 702 } ] }, { "id" : 137780, "points" : [ { "x" : 405, "y" : 670 } ] }, { "id" : 137781, "points" : [ { "x" : 394, "y" : 697 } ] } ], "catalysts" : [ { "id" : 137776, "points" : [ { "x" : 467, "y" : 634 } ] } ] }, { "id" : 137750, "reactomeId" : 11038396, "displayName" : "SAMHD1:Zn2+ tetramer hydrolyzes dNTP to nucleoside and triphosphate", "schemaClass" : "Reaction", "renderableClass" : "Reaction", "position" : { "x" : 1375, "y" : 433 }, "minX" : 1369, "maxX" : 1381, "minY" : 405, "maxY" : 473, "reactionType" : "transition", "segments" : [ { "from" : { "x" : 1372, "y" : 405 }, "to" : { "x" : 1375, "y" : 433 } }, { "from" : { "x" : 1375, "y" : 433 }, "to" : { "x" : 1376, "y" : 473 } } ], "reactionShape" : { "a" : { "x" : 1369, "y" : 427 }, "b" : { "x" : 1381, "y" : 439 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 1375, "y" : 433 } }, "inputs" : [ { "id" : 137751, "points" : [ { "x" : 1347, "y" : 391 } ] }, { "id" : 137752, "points" : [ { "x" : 1415, "y" : 381 } ] } ], "outputs" : [ { "id" : 137753, "points" : [ { "x" : 1402, "y" : 481 } ] }, { "id" : 137754, "points" : [ { "x" : 1378, "y" : 514 } ] }, { "id" : 137755, "points" : [ { "x" : 1348, "y" : 480 } ] } ], "catalysts" : [ { "id" : 137756, "points" : [ { "x" : 1407, "y" : 434 } ] } ], "activators" : [ { "id" : 137757, "points" : [ { "x" : 1345, "y" : 431 } ] } ] }, { "id" : 137782, "reactomeId" : 11000784, "displayName" : "XDH oxidizes xanthine to form urate", "schemaClass" : "Reaction", "renderableClass" : "Reaction", "position" : { "x" : 324, "y" : 803 }, "minX" : 318, "maxX" : 330, "minY" : 764, "maxY" : 834, "reactionType" : "transition", "segments" : [ { "from" : { "x" : 324, "y" : 764 }, "to" : { "x" : 324, "y" : 803 } }, { "from" : { "x" : 324, "y" : 803 }, "to" : { "x" : 322, "y" : 834 } } ], "reactionShape" : { "a" : { "x" : 318, "y" : 797 }, "b" : { "x" : 330, "y" : 809 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 324, "y" : 803 } }, "inputs" : [ { "id" : 137768, "points" : [ { "x" : 338, "y" : 739 } ] }, { "id" : 137783, "points" : [ { "x" : 281, "y" : 745 } ] }, { "id" : 137784, "points" : [ { "x" : 286, "y" : 774 } ] } ], "outputs" : [ { "id" : 137785, "points" : [ { "x" : 333, "y" : 866 } ] }, { "id" : 137786, "points" : [ { "x" : 299, "y" : 846 } ] } ], "catalysts" : [ { "id" : 137776, "points" : [ { "x" : 506, "y" : 647 }, { "x" : 506, "y" : 780 } ] } ] }, { "id" : 137813, "reactomeId" : 11000800, "displayName" : "(deoxy)uridine + orthophosphate <=> uracil + (deoxy)ribose 1-phosphate (UPP)", "schemaClass" : "Reaction", "renderableClass" : "Reaction", "position" : { "x" : 555, "y" : 956 }, "minX" : 549, "maxX" : 561, "minY" : 919, "maxY" : 981, "reactionType" : "transition", "segments" : [ { "from" : { "x" : 553, "y" : 919 }, "to" : { "x" : 555, "y" : 956 } }, { "from" : { "x" : 555, "y" : 956 }, "to" : { "x" : 556, "y" : 981 } } ], "reactionShape" : { "a" : { "x" : 549, "y" : 950 }, "b" : { "x" : 561, "y" : 962 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 555, "y" : 956 } }, "inputs" : [ { "id" : 137814, "points" : [ { "x" : 553, "y" : 886 } ] }, { "id" : 137815, "points" : [ { "x" : 590, "y" : 893 } ] } ], "outputs" : [ { "id" : 137816, "points" : [ { "x" : 556, "y" : 1028 } ] }, { "id" : 137817, "points" : [ { "x" : 598, "y" : 993 } ] } ], "catalysts" : [ { "id" : 137818, "points" : [ { "x" : 581, "y" : 952 } ] } ] }, { "id" : 137819, "reactomeId" : 11000034, "displayName" : "reduction of uracil to form dihydrouracil", "schemaClass" : "Reaction", "renderableClass" : "Reaction", "position" : { "x" : 1079, "y" : 742 }, "minX" : 1073, "maxX" : 1085, "minY" : 708, "maxY" : 773, "reactionType" : "transition", "segments" : [ { "from" : { "x" : 1078, "y" : 708 }, "to" : { "x" : 1079, "y" : 742 } }, { "from" : { "x" : 1079, "y" : 742 }, "to" : { "x" : 1078, "y" : 773 } } ], "reactionShape" : { "a" : { "x" : 1073, "y" : 736 }, "b" : { "x" : 1085, "y" : 748 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 1079, "y" : 742 } }, "inputs" : [ { "id" : 137820, "points" : [ { "x" : 1147, "y" : 705 } ] }, { "id" : 137821, "points" : [ { "x" : 1137, "y" : 676 } ] }, { "id" : 137822, "points" : [ { "x" : 1078, "y" : 668 } ] } ], "outputs" : [ { "id" : 137823, "points" : [ { "x" : 1078, "y" : 806 } ] }, { "id" : 137824, "points" : [ { "x" : 1136, "y" : 787 } ] } ], "catalysts" : [ { "id" : 137825, "points" : [ { "x" : 1127, "y" : 747 } ] } ] }, { "id" : 137787, "reactomeId" : 11045973, "displayName" : "XDH dehydrogenates xanthine to form urate", "schemaClass" : "Reaction", "renderableClass" : "Reaction", "position" : { "x" : 377, "y" : 814 }, "minX" : 371, "maxX" : 383, "minY" : 763, "maxY" : 846, "reactionType" : "transition", "segments" : [ { "from" : { "x" : 375, "y" : 763 }, "to" : { "x" : 377, "y" : 814 } }, { "from" : { "x" : 377, "y" : 814 }, "to" : { "x" : 377, "y" : 846 } } ], "reactionShape" : { "a" : { "x" : 371, "y" : 808 }, "b" : { "x" : 383, "y" : 820 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 377, "y" : 814 } }, "inputs" : [ { "id" : 137768, "points" : [ { "x" : 357, "y" : 739 } ] }, { "id" : 137788, "points" : [ { "x" : 432, "y" : 755 } ] }, { "id" : 137789, "points" : [ { "x" : 433, "y" : 728 } ] } ], "outputs" : [ { "id" : 137785, "points" : [ { "x" : 354, "y" : 866 } ] }, { "id" : 137790, "points" : [ { "x" : 410, "y" : 845 } ] }, { "id" : 137791, "points" : [ { "x" : 410, "y" : 876 } ] } ], "catalysts" : [ { "id" : 137776, "points" : [ { "x" : 507, "y" : 647 }, { "x" : 523, "y" : 789 } ] } ] }, { "id" : 137758, "reactomeId" : 11000771, "displayName" : "(d)GMP or (d)IMP + H2O => (2'-deoxy)guanosine or (2'-deoxy)inosine + orthophosphate (NT5C2)", "schemaClass" : "Reaction", "renderableClass" : "Reaction", "position" : { "x" : 186, "y" : 179 }, "minX" : 180, "maxX" : 192, "minY" : 134, "maxY" : 207, "reactionType" : "transition", "segments" : [ { "from" : { "x" : 185, "y" : 134 }, "to" : { "x" : 186, "y" : 179 } }, { "from" : { "x" : 186, "y" : 179 }, "to" : { "x" : 186, "y" : 207 } } ], "reactionShape" : { "a" : { "x" : 180, "y" : 173 }, "b" : { "x" : 192, "y" : 185 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 186, "y" : 179 } }, "inputs" : [ { "id" : 137759, "points" : [ { "x" : 168, "y" : 82 } ] }, { "id" : 137760, "points" : [ { "x" : 199, "y" : 126 } ] } ], "outputs" : [ { "id" : 137761, "points" : [ { "x" : 171, "y" : 252 } ] }, { "id" : 137762, "points" : [ { "x" : 210, "y" : 215 } ] } ], "catalysts" : [ { "id" : 137763, "points" : [ { "x" : 132, "y" : 182 } ] } ] } ], "compartments" : [ { "id" : 137906, "reactomeId" : 17963, "displayName" : "Golgi lumen", "schemaClass" : "Compartment", "renderableClass" : "Compartment", "position" : { "x" : 1598, "y" : 1256 }, "minX" : 1295, "maxX" : 1901, "minY" : 1177, "maxY" : 1336, "prop" : { "x" : 1295, "y" : 1177, "width" : 606, "height" : 159 }, "textPosition" : { "x" : 1308, "y" : 1288 }, "insets" : { "x" : 1305, "y" : 1187, "width" : 586, "height" : 139 }, "bgColor" : { "r" : 250, "g" : 240, "b" : 240 }, "componentIds" : [ 137976, 137978 ] }, { "id" : 137844, "reactomeId" : 70101, "displayName" : "cytosol", "schemaClass" : "Compartment", "renderableClass" : "Compartment", "position" : { "x" : 976, "y" : 689 }, "minX" : 0, "maxX" : 1952, "minY" : 0, "maxY" : 1379, "prop" : { "x" : 0, "y" : 0, "width" : 1952, "height" : 1379 }, "textPosition" : { "x" : 106, "y" : 1263 }, "insets" : { "x" : 10, "y" : 10, "width" : 1932, "height" : 1359 }, "bgColor" : { "r" : 250, "g" : 240, "b" : 240 }, "componentIds" : [ 137845, 137761, 137762, 137763, 137760, 137759, 137766, 137772, 137768, 137769, 137770, 137773, 137774, 137776, 137785, 137783, 137786, 137861, 137793, 137794, 137795, 137798, 137796, 137800, 137801, 137803, 137805, 137806, 137802, 137811, 137808, 137809, 137814, 137818, 137815, 137817, 137820, 137821, 137823, 137824, 137825, 137822, 137827, 137828, 137830, 137832, 137833, 137834, 137836, 137835, 137838, 137841, 137843, 137816, 137906, 137917, 137778, 137790, 137781, 137779, 137780, 137791, 137775, 137784, 137981, 137982, 137979, 137839, 137758, 137764, 137771, 137777, 137782, 137787, 137788, 137789, 137792, 137799, 137807, 137810, 137813, 137819, 137826, 137831, 137837, 137840, 137842, 137987, 137812, 137765, 137767, 137804, 137829, 137972, 137988, 137797 ] }, { "id" : 137845, "reactomeId" : 5460, "displayName" : "mitochondrial matrix", "schemaClass" : "Compartment", "renderableClass" : "Compartment", "position" : { "x" : 1522, "y" : 833 }, "minX" : 1311, "maxX" : 1734, "minY" : 637, "maxY" : 1030, "prop" : { "x" : 1311, "y" : 637, "width" : 423, "height" : 393 }, "textPosition" : { "x" : 1553, "y" : 958 }, "insets" : { "x" : 1321, "y" : 647, "width" : 403, "height" : 373 }, "bgColor" : { "r" : 250, "g" : 240, "b" : 240 } }, { "id" : 137861, "reactomeId" : 7660, "displayName" : "nucleoplasm", "schemaClass" : "Compartment", "renderableClass" : "Compartment", "position" : { "x" : 1297, "y" : 461 }, "minX" : 1068, "maxX" : 1527, "minY" : 312, "maxY" : 610, "prop" : { "x" : 1068, "y" : 312, "width" : 459, "height" : 298 }, "textPosition" : { "x" : 1422, "y" : 566 }, "insets" : { "x" : 1078, "y" : 322, "width" : 439, "height" : 278 }, "bgColor" : { "r" : 250, "g" : 240, "b" : 240 }, "componentIds" : [ 137754, 137751, 137752, 137750, 137753, 137757, 137756, 137755 ] }, { "id" : 137917, "reactomeId" : 528865, "displayName" : "endocytic vesicle lumen", "schemaClass" : "Compartment", "renderableClass" : "Compartment", "position" : { "x" : 1074, "y" : 1258 }, "minX" : 898, "maxX" : 1251, "minY" : 1184, "maxY" : 1332, "prop" : { "x" : 898, "y" : 1184, "width" : 353, "height" : 148 }, "textPosition" : { "x" : 913, "y" : 1285 }, "insets" : { "x" : 908, "y" : 1194, "width" : 333, "height" : 128 }, "bgColor" : { "r" : 250, "g" : 240, "b" : 240 } } ], "notes" : [ ], "links" : [ ], "shadows" : [ { "id" : 137974, "reactomeId" : 11049104, "displayName" : "Purine catabolism", "schemaClass" : "Pathway", "renderableClass" : "Shadow", "position" : { "x" : 529, "y" : 481 }, "minX" : 15, "maxX" : 1044, "minY" : 43, "maxY" : 920, "prop" : { "x" : 15, "y" : 43, "width" : 1029, "height" : 581 }, "points" : [ { "x" : 15, "y" : 43 }, { "x" : 1044, "y" : 43 }, { "x" : 1044, "y" : 920 }, { "x" : 15, "y" : 920 } ], "colour" : "#dc3912" }, { "id" : 137973, "reactomeId" : 11049060, "displayName" : "Pyrimidine catabolism", "schemaClass" : "Pathway", "renderableClass" : "Shadow", "position" : { "x" : 1025, "y" : 893 }, "minX" : 522, "maxX" : 1528, "minY" : 624, "maxY" : 1162, "prop" : { "x" : 522, "y" : 920, "width" : 1006, "height" : 242 }, "points" : [ { "x" : 522, "y" : 624 }, { "x" : 1528, "y" : 624 }, { "x" : 1528, "y" : 1162 }, { "x" : 522, "y" : 1162 } ], "colour" : "#4684ee" } ], "minX" : 0, "maxX" : 1952, "minY" : 0, "maxY" : 1379, "disease" : false }