{ "dbId" : 11048992, "stableId" : "R-DDI-77289", "displayName" : "Mitochondrial Fatty Acid Beta-Oxidation", "nodes" : [ { "id" : 149770, "reactomeId" : 77252, "displayName" : "(S)-3-Hydroxydodecanoyl-CoA", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 1043, "y" : 424 }, "minX" : 978, "maxX" : 1110, "minY" : 397, "maxY" : 450, "prop" : { "x" : 978, "y" : 398, "width" : 131, "height" : 52 }, "textPosition" : { "x" : 979, "y" : 399 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1104, "y" : 403 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1104, "y" : 403 } } }, "connectors" : [ { "edgeId" : 149767, "type" : "OUTPUT", "segments" : [ ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 149771, "reactomeId" : 10998431, "displayName" : "ECHS1 hexamer", "schemaClass" : "Complex", "renderableClass" : "Complex", "position" : { "x" : 1114, "y" : 357 }, "minX" : 1055, "maxX" : 1154, "minY" : 333, "maxY" : 375, "prop" : { "x" : 1081, "y" : 339, "width" : 67, "height" : 36 }, "textPosition" : { "x" : 1083, "y" : 340 }, "bgColor" : { "r" : 204, "g" : 255, "b" : 255 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1148, "y" : 339 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1148, "y" : 339 } } }, "connectors" : [ { "edgeId" : 149767, "type" : "CATALYST", "segments" : [ { "from" : { "x" : 1078, "y" : 359 }, "to" : { "x" : 1063, "y" : 360 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "c" : { "x" : 1059, "y" : 360 }, "r" : 4, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1059, "y" : 360 } } } ] }, { "id" : 149768, "reactomeId" : 77255, "displayName" : "2-trans-Dodecenoyl-CoA", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 1046, "y" : 296 }, "minX" : 982, "maxX" : 1112, "minY" : 273, "maxY" : 338, "prop" : { "x" : 982, "y" : 274, "width" : 129, "height" : 44 }, "textPosition" : { "x" : 992, "y" : 278 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1106, "y" : 279 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1106, "y" : 279 } } }, "connectors" : [ { "edgeId" : 149767, "type" : "INPUT", "segments" : [ { "from" : { "x" : 1046, "y" : 321 }, "to" : { "x" : 1046, "y" : 338 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 149769, "reactomeId" : 113521, "displayName" : "H2O", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 1148, "y" : 307 }, "minX" : 1046, "maxX" : 1170, "minY" : 291, "maxY" : 338, "prop" : { "x" : 1127, "y" : 292, "width" : 42, "height" : 30 }, "textPosition" : { "x" : 1131, "y" : 296 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1164, "y" : 297 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1164, "y" : 297 } } }, "connectors" : [ { "edgeId" : 149767, "type" : "INPUT", "segments" : [ { "from" : { "x" : 1124, "y" : 313 }, "to" : { "x" : 1046, "y" : 338 } } ], "stoichiometry" : { "value" : 1 } } ], "trivial" : true }, { "id" : 149774, "reactomeId" : 113521, "displayName" : "H2O", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 337, "y" : 439 }, "minX" : 316, "maxX" : 359, "minY" : 412, "maxY" : 454, "prop" : { "x" : 316, "y" : 424, "width" : 42, "height" : 30 }, "textPosition" : { "x" : 320, "y" : 428 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 353, "y" : 429 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 353, "y" : 429 } } }, "connectors" : [ { "edgeId" : 149772, "type" : "INPUT", "segments" : [ { "from" : { "x" : 330, "y" : 421 }, "to" : { "x" : 325, "y" : 412 } } ], "stoichiometry" : { "value" : 1 } } ], "trivial" : true }, { "id" : 149775, "reactomeId" : 77341, "displayName" : "(S)-Hydroxydecanoyl-CoA", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 212, "y" : 413 }, "minX" : 144, "maxX" : 281, "minY" : 382, "maxY" : 444, "prop" : { "x" : 144, "y" : 383, "width" : 136, "height" : 61 }, "textPosition" : { "x" : 154, "y" : 389 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 275, "y" : 388 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 275, "y" : 388 } } }, "connectors" : [ { "edgeId" : 149772, "type" : "OUTPUT", "segments" : [ ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 149773, "reactomeId" : 77343, "displayName" : "tdec2-CoA", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 394, "y" : 414 }, "minX" : 325, "maxX" : 459, "minY" : 391, "maxY" : 437, "prop" : { "x" : 365, "y" : 392, "width" : 59, "height" : 45 }, "textPosition" : { "x" : 370, "y" : 397 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 419, "y" : 397 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 419, "y" : 397 } } }, "connectors" : [ { "edgeId" : 149772, "type" : "INPUT", "segments" : [ { "from" : { "x" : 362, "y" : 413 }, "to" : { "x" : 325, "y" : 412 } } ], "stoichiometry" : { "value" : 1 } }, { "edgeId" : 149810, "type" : "INPUT", "segments" : [ { "from" : { "x" : 427, "y" : 405 }, "to" : { "x" : 459, "y" : 396 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 149778, "reactomeId" : 77332, "displayName" : "trans-Oct-2-enoyl-CoA", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 603, "y" : 558 }, "minX" : 551, "maxX" : 668, "minY" : 534, "maxY" : 582, "prop" : { "x" : 551, "y" : 535, "width" : 105, "height" : 47 }, "textPosition" : { "x" : 562, "y" : 541 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 651, "y" : 540 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 651, "y" : 540 } } }, "connectors" : [ { "edgeId" : 149777, "type" : "INPUT", "segments" : [ { "from" : { "x" : 659, "y" : 557 }, "to" : { "x" : 668, "y" : 557 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 149779, "reactomeId" : 113521, "displayName" : "H2O", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 665, "y" : 601 }, "minX" : 644, "maxX" : 687, "minY" : 557, "maxY" : 616, "prop" : { "x" : 644, "y" : 586, "width" : 42, "height" : 30 }, "textPosition" : { "x" : 648, "y" : 590 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 681, "y" : 591 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 681, "y" : 591 } } }, "connectors" : [ { "edgeId" : 149777, "type" : "INPUT", "segments" : [ { "from" : { "x" : 666, "y" : 583 }, "to" : { "x" : 668, "y" : 557 } } ], "stoichiometry" : { "value" : 1 } } ], "trivial" : true }, { "id" : 149776, "reactomeId" : 10998431, "displayName" : "ECHS1 hexamer", "schemaClass" : "Complex", "renderableClass" : "Complex", "position" : { "x" : 309, "y" : 361 }, "minX" : 255, "maxX" : 369, "minY" : 344, "maxY" : 404, "prop" : { "x" : 255, "y" : 350, "width" : 108, "height" : 22 }, "textPosition" : { "x" : 255, "y" : 351 }, "bgColor" : { "r" : 204, "g" : 255, "b" : 255 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 363, "y" : 350 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 363, "y" : 350 } } }, "connectors" : [ { "edgeId" : 149772, "type" : "CATALYST", "segments" : [ { "from" : { "x" : 308, "y" : 375 }, "to" : { "x" : 308, "y" : 396 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "c" : { "x" : 308, "y" : 400 }, "r" : 4, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 308, "y" : 400 } } } ] }, { "id" : 149783, "reactomeId" : 77324, "displayName" : "trans-Hex-2-enoyl-CoA", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 838, "y" : 715 }, "minX" : 769, "maxX" : 891, "minY" : 695, "maxY" : 735, "prop" : { "x" : 787, "y" : 696, "width" : 103, "height" : 39 }, "textPosition" : { "x" : 796, "y" : 698 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 885, "y" : 701 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 885, "y" : 701 } } }, "connectors" : [ { "edgeId" : 149782, "type" : "INPUT", "segments" : [ { "from" : { "x" : 784, "y" : 713 }, "to" : { "x" : 769, "y" : 713 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 149780, "reactomeId" : 77330, "displayName" : "(S)-Hydroxyoctanoyl-CoA", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 781, "y" : 556 }, "minX" : 723, "maxX" : 840, "minY" : 531, "maxY" : 581, "prop" : { "x" : 723, "y" : 532, "width" : 116, "height" : 49 }, "textPosition" : { "x" : 724, "y" : 532 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 834, "y" : 537 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 834, "y" : 537 } } }, "connectors" : [ { "edgeId" : 149777, "type" : "OUTPUT", "segments" : [ ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 149781, "reactomeId" : 10998431, "displayName" : "ECHS1 hexamer", "schemaClass" : "Complex", "renderableClass" : "Complex", "position" : { "x" : 682, "y" : 493 }, "minX" : 647, "maxX" : 723, "minY" : 470, "maxY" : 548, "prop" : { "x" : 647, "y" : 476, "width" : 70, "height" : 35 }, "textPosition" : { "x" : 651, "y" : 476 }, "bgColor" : { "r" : 204, "g" : 255, "b" : 255 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 717, "y" : 476 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 717, "y" : 476 } } }, "connectors" : [ { "edgeId" : 149777, "type" : "CATALYST", "segments" : [ { "from" : { "x" : 683, "y" : 514 }, "to" : { "x" : 685, "y" : 540 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "c" : { "x" : 686, "y" : 544 }, "r" : 4, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 686, "y" : 544 } } } ] }, { "id" : 149786, "reactomeId" : 10998431, "displayName" : "ECHS1 hexamer", "schemaClass" : "Complex", "renderableClass" : "Complex", "position" : { "x" : 754, "y" : 762 }, "minX" : 723, "maxX" : 791, "minY" : 723, "maxY" : 780, "prop" : { "x" : 723, "y" : 744, "width" : 62, "height" : 36 }, "textPosition" : { "x" : 723, "y" : 745 }, "bgColor" : { "r" : 204, "g" : 255, "b" : 255 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 785, "y" : 744 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 785, "y" : 744 } } }, "connectors" : [ { "edgeId" : 149782, "type" : "CATALYST", "segments" : [ { "from" : { "x" : 752, "y" : 741 }, "to" : { "x" : 751, "y" : 731 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "c" : { "x" : 751, "y" : 727 }, "r" : 4, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 751, "y" : 727 } } } ] }, { "id" : 149784, "reactomeId" : 113521, "displayName" : "H2O", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 783, "y" : 669 }, "minX" : 762, "maxX" : 805, "minY" : 653, "maxY" : 713, "prop" : { "x" : 762, "y" : 654, "width" : 42, "height" : 30 }, "textPosition" : { "x" : 766, "y" : 658 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 799, "y" : 659 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 799, "y" : 659 } } }, "connectors" : [ { "edgeId" : 149782, "type" : "INPUT", "segments" : [ { "from" : { "x" : 778, "y" : 687 }, "to" : { "x" : 769, "y" : 713 } } ], "stoichiometry" : { "value" : 1 } } ], "trivial" : true }, { "id" : 149785, "reactomeId" : 77322, "displayName" : "(S)-Hydroxyhexanoyl-CoA", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 665, "y" : 717 }, "minX" : 605, "maxX" : 726, "minY" : 692, "maxY" : 742, "prop" : { "x" : 605, "y" : 693, "width" : 120, "height" : 49 }, "textPosition" : { "x" : 607, "y" : 693 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 720, "y" : 698 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 720, "y" : 698 } } }, "connectors" : [ { "edgeId" : 149782, "type" : "OUTPUT", "segments" : [ ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 149790, "reactomeId" : 77251, "displayName" : "3HB-CoA", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 477, "y" : 830 }, "minX" : 439, "maxX" : 517, "minY" : 814, "maxY" : 845, "prop" : { "x" : 439, "y" : 815, "width" : 77, "height" : 30 }, "textPosition" : { "x" : 447, "y" : 819 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 511, "y" : 820 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 511, "y" : 820 } } }, "connectors" : [ { "edgeId" : 149787, "type" : "OUTPUT", "segments" : [ ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 149791, "reactomeId" : 10998431, "displayName" : "ECHS1 hexamer", "schemaClass" : "Complex", "renderableClass" : "Complex", "position" : { "x" : 422, "y" : 763 }, "minX" : 389, "maxX" : 461, "minY" : 739, "maxY" : 821, "prop" : { "x" : 389, "y" : 745, "width" : 66, "height" : 36 }, "textPosition" : { "x" : 391, "y" : 746 }, "bgColor" : { "r" : 204, "g" : 255, "b" : 255 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 455, "y" : 745 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 455, "y" : 745 } } }, "connectors" : [ { "edgeId" : 149787, "type" : "CATALYST", "segments" : [ { "from" : { "x" : 417, "y" : 784 }, "to" : { "x" : 410, "y" : 813 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "c" : { "x" : 410, "y" : 817 }, "r" : 4, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 410, "y" : 817 } } } ] }, { "id" : 149788, "reactomeId" : 113521, "displayName" : "H2O", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 387, "y" : 873 }, "minX" : 366, "maxX" : 409, "minY" : 829, "maxY" : 888, "prop" : { "x" : 366, "y" : 858, "width" : 42, "height" : 30 }, "textPosition" : { "x" : 370, "y" : 862 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 403, "y" : 863 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 403, "y" : 863 } } }, "connectors" : [ { "edgeId" : 149787, "type" : "INPUT", "segments" : [ { "from" : { "x" : 387, "y" : 855 }, "to" : { "x" : 389, "y" : 829 } } ], "stoichiometry" : { "value" : 1 } } ], "trivial" : true }, { "id" : 149789, "reactomeId" : 77313, "displayName" : "Crotonoyl-CoA", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 322, "y" : 834 }, "minX" : 271, "maxX" : 389, "minY" : 818, "maxY" : 849, "prop" : { "x" : 271, "y" : 819, "width" : 103, "height" : 30 }, "textPosition" : { "x" : 275, "y" : 823 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 369, "y" : 824 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 369, "y" : 824 } } }, "connectors" : [ { "edgeId" : 149787, "type" : "INPUT", "segments" : [ { "from" : { "x" : 377, "y" : 830 }, "to" : { "x" : 389, "y" : 829 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 149794, "reactomeId" : 113593, "displayName" : "ATP", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 1212, "y" : 762 }, "minX" : 1192, "maxX" : 1272, "minY" : 746, "maxY" : 778, "prop" : { "x" : 1192, "y" : 747, "width" : 40, "height" : 31 }, "textPosition" : { "x" : 1196, "y" : 752 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1227, "y" : 752 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1227, "y" : 752 } } }, "connectors" : [ { "edgeId" : 149792, "type" : "INPUT", "segments" : [ { "from" : { "x" : 1235, "y" : 766 }, "to" : { "x" : 1272, "y" : 775 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 149795, "reactomeId" : 29896, "displayName" : "HCO3-", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 1330, "y" : 765 }, "minX" : 1272, "maxX" : 1360, "minY" : 749, "maxY" : 781, "prop" : { "x" : 1301, "y" : 750, "width" : 58, "height" : 31 }, "textPosition" : { "x" : 1307, "y" : 755 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1354, "y" : 755 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1354, "y" : 755 } } }, "connectors" : [ { "edgeId" : 149792, "type" : "INPUT", "segments" : [ { "from" : { "x" : 1298, "y" : 770 }, "to" : { "x" : 1272, "y" : 775 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 149793, "reactomeId" : 70843, "displayName" : "PROP-CoA", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 1273, "y" : 734 }, "minX" : 1231, "maxX" : 1317, "minY" : 718, "maxY" : 775, "prop" : { "x" : 1231, "y" : 719, "width" : 85, "height" : 30 }, "textPosition" : { "x" : 1239, "y" : 723 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1311, "y" : 724 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1311, "y" : 724 } } }, "connectors" : [ { "edgeId" : 149792, "type" : "INPUT", "segments" : [ { "from" : { "x" : 1272, "y" : 752 }, "to" : { "x" : 1272, "y" : 775 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 149798, "reactomeId" : 113548, "displayName" : "Pi", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 1326, "y" : 862 }, "minX" : 1273, "maxX" : 1340, "minY" : 834, "maxY" : 877, "prop" : { "x" : 1314, "y" : 847, "width" : 25, "height" : 30 }, "textPosition" : { "x" : 1317, "y" : 851 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1334, "y" : 852 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1334, "y" : 852 } } }, "connectors" : [ { "edgeId" : 149792, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 1311, "y" : 855 }, "to" : { "x" : 1273, "y" : 834 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 1303, "y" : 855 }, "b" : { "x" : 1311, "y" : 855 }, "c" : { "x" : 1307, "y" : 848 }, "type" : "ARROW", "centre" : { "x" : 1307, "y" : 848 } } } ] }, { "id" : 149799, "reactomeId" : 113529, "displayName" : "H+", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 1324, "y" : 823 }, "minX" : 1273, "maxX" : 1342, "minY" : 807, "maxY" : 838, "prop" : { "x" : 1307, "y" : 808, "width" : 34, "height" : 30 }, "textPosition" : { "x" : 1310, "y" : 812 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1336, "y" : 813 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1336, "y" : 813 } } }, "connectors" : [ { "edgeId" : 149792, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 1304, "y" : 826 }, "to" : { "x" : 1273, "y" : 834 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 1298, "y" : 832 }, "b" : { "x" : 1304, "y" : 826 }, "c" : { "x" : 1296, "y" : 824 }, "type" : "ARROW", "centre" : { "x" : 1296, "y" : 824 } } } ], "trivial" : true }, { "id" : 149796, "reactomeId" : 71019, "displayName" : "MEMA-CoA", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 1273, "y" : 889 }, "minX" : 1231, "maxX" : 1317, "minY" : 834, "maxY" : 904, "prop" : { "x" : 1231, "y" : 874, "width" : 85, "height" : 30 }, "textPosition" : { "x" : 1237, "y" : 878 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1311, "y" : 879 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1311, "y" : 879 } } }, "connectors" : [ { "edgeId" : 149792, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 1273, "y" : 871 }, "to" : { "x" : 1273, "y" : 834 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 1269, "y" : 864 }, "b" : { "x" : 1273, "y" : 871 }, "c" : { "x" : 1277, "y" : 864 }, "type" : "ARROW", "centre" : { "x" : 1277, "y" : 864 } } }, { "edgeId" : 149801, "type" : "INPUT", "segments" : [ ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 149797, "reactomeId" : 113581, "displayName" : "ADP", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 1213, "y" : 852 }, "minX" : 1193, "maxX" : 1273, "minY" : 834, "maxY" : 868, "prop" : { "x" : 1193, "y" : 837, "width" : 41, "height" : 31 }, "textPosition" : { "x" : 1197, "y" : 842 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1229, "y" : 842 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1229, "y" : 842 } } }, "connectors" : [ { "edgeId" : 149792, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 1237, "y" : 845 }, "to" : { "x" : 1273, "y" : 834 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 1242, "y" : 839 }, "b" : { "x" : 1237, "y" : 845 }, "c" : { "x" : 1245, "y" : 847 }, "type" : "ARROW", "centre" : { "x" : 1245, "y" : 847 } } } ] }, { "id" : 149802, "reactomeId" : 71009, "displayName" : "L-MM-CoA", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 1273, "y" : 986 }, "minX" : 1231, "maxX" : 1317, "minY" : 970, "maxY" : 1001, "prop" : { "x" : 1231, "y" : 971, "width" : 85, "height" : 30 }, "textPosition" : { "x" : 1240, "y" : 975 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1311, "y" : 976 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1311, "y" : 976 } } }, "connectors" : [ { "edgeId" : 149801, "type" : "OUTPUT", "segments" : [ ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 149803, "reactomeId" : 10998641, "displayName" : "MCEE", "schemaClass" : "EntityWithAccessionedSequence", "renderableClass" : "Protein", "position" : { "x" : 1209, "y" : 934 }, "minX" : 1188, "maxX" : 1265, "minY" : 917, "maxY" : 945, "prop" : { "x" : 1188, "y" : 923, "width" : 43, "height" : 22 }, "textPosition" : { "x" : 1188, "y" : 923 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1231, "y" : 923 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1231, "y" : 923 } } }, "connectors" : [ { "edgeId" : 149801, "type" : "CATALYST", "segments" : [ { "from" : { "x" : 1234, "y" : 933 }, "to" : { "x" : 1257, "y" : 932 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "c" : { "x" : 1261, "y" : 932 }, "r" : 4, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1261, "y" : 932 } } } ] }, { "id" : 149800, "reactomeId" : 10998659, "displayName" : "6x(Btn-PCCA:PCCB)", "schemaClass" : "Complex", "renderableClass" : "Complex", "position" : { "x" : 1177, "y" : 796 }, "minX" : 1114, "maxX" : 1265, "minY" : 779, "maxY" : 807, "prop" : { "x" : 1114, "y" : 785, "width" : 126, "height" : 22 }, "textPosition" : { "x" : 1114, "y" : 786 }, "bgColor" : { "r" : 204, "g" : 255, "b" : 255 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1240, "y" : 785 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1240, "y" : 785 } } }, "connectors" : [ { "edgeId" : 149792, "type" : "CATALYST", "segments" : [ { "from" : { "x" : 1243, "y" : 796 }, "to" : { "x" : 1257, "y" : 796 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "c" : { "x" : 1261, "y" : 797 }, "r" : 4, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1261, "y" : 797 } } } ] }, { "id" : 149806, "reactomeId" : 11032003, "displayName" : "phospho-ndufab1", "schemaClass" : "EntityWithAccessionedSequence", "renderableClass" : "Protein", "position" : { "x" : 1170, "y" : 1393 }, "minX" : 1138, "maxX" : 1213, "minY" : 1346, "maxY" : 1405, "prop" : { "x" : 1138, "y" : 1382, "width" : 64, "height" : 23 }, "textPosition" : { "x" : 1138, "y" : 1376 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1202, "y" : 1382 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1202, "y" : 1382 } } }, "connectors" : [ { "edgeId" : 149804, "type" : "INPUT", "segments" : [ { "from" : { "x" : 1180, "y" : 1379 }, "to" : { "x" : 1213, "y" : 1346 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 149807, "reactomeId" : 11040857, "displayName" : "phospho-ndufab1", "schemaClass" : "EntityWithAccessionedSequence", "renderableClass" : "Protein", "position" : { "x" : 1317, "y" : 1396 }, "minX" : 1258, "maxX" : 1383, "minY" : 1347, "maxY" : 1414, "prop" : { "x" : 1258, "y" : 1378, "width" : 119, "height" : 36 }, "textPosition" : { "x" : 1258, "y" : 1385 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1377, "y" : 1378 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1377, "y" : 1378 } } }, "connectors" : [ { "edgeId" : 149804, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 1301, "y" : 1375 }, "to" : { "x" : 1275, "y" : 1347 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 1293, "y" : 1373 }, "b" : { "x" : 1301, "y" : 1375 }, "c" : { "x" : 1299, "y" : 1367 }, "type" : "ARROW", "centre" : { "x" : 1299, "y" : 1367 } } } ] }, { "id" : 149932, "reactomeId" : 70958, "displayName" : "SUCC-CoA", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 1275, "y" : 1076 }, "minX" : 1233, "maxX" : 1319, "minY" : 1060, "maxY" : 1091, "prop" : { "x" : 1233, "y" : 1061, "width" : 85, "height" : 30 }, "textPosition" : { "x" : 1241, "y" : 1065 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1313, "y" : 1066 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1313, "y" : 1066 } } }, "connectors" : [ ] }, { "id" : 149805, "reactomeId" : 977314, "displayName" : "Malonyl-CoA", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 1155, "y" : 1321 }, "minX" : 1110, "maxX" : 1213, "minY" : 1305, "maxY" : 1346, "prop" : { "x" : 1110, "y" : 1306, "width" : 90, "height" : 30 }, "textPosition" : { "x" : 1114, "y" : 1310 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1195, "y" : 1311 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1195, "y" : 1311 } } }, "connectors" : [ { "edgeId" : 149804, "type" : "INPUT", "segments" : [ { "from" : { "x" : 1189, "y" : 1339 }, "to" : { "x" : 1213, "y" : 1346 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 149811, "reactomeId" : 113529, "displayName" : "H+", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 413, "y" : 375 }, "minX" : 396, "maxX" : 459, "minY" : 359, "maxY" : 396, "prop" : { "x" : 396, "y" : 360, "width" : 34, "height" : 30 }, "textPosition" : { "x" : 399, "y" : 364 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 425, "y" : 365 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 425, "y" : 365 } } }, "connectors" : [ { "edgeId" : 149810, "type" : "INPUT", "segments" : [ { "from" : { "x" : 433, "y" : 382 }, "to" : { "x" : 459, "y" : 396 } } ], "stoichiometry" : { "value" : 1 } } ], "trivial" : true }, { "id" : 149808, "reactomeId" : 29374, "displayName" : "CoA-SH", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 1322, "y" : 1310 }, "minX" : 1275, "maxX" : 1357, "minY" : 1294, "maxY" : 1347, "prop" : { "x" : 1288, "y" : 1295, "width" : 68, "height" : 30 }, "textPosition" : { "x" : 1295, "y" : 1299 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1351, "y" : 1300 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1351, "y" : 1300 } } }, "connectors" : [ { "edgeId" : 149804, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 1302, "y" : 1328 }, "to" : { "x" : 1275, "y" : 1347 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 1299, "y" : 1335 }, "b" : { "x" : 1302, "y" : 1328 }, "c" : { "x" : 1294, "y" : 1329 }, "type" : "ARROW", "centre" : { "x" : 1294, "y" : 1329 } } } ] }, { "id" : 149809, "reactomeId" : 11040862, "displayName" : "MCAT", "schemaClass" : "EntityWithAccessionedSequence", "renderableClass" : "Protein", "position" : { "x" : 1237, "y" : 1290 }, "minX" : 1216, "maxX" : 1265, "minY" : 1273, "maxY" : 1339, "prop" : { "x" : 1216, "y" : 1279, "width" : 43, "height" : 22 }, "textPosition" : { "x" : 1217, "y" : 1279 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1259, "y" : 1279 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1259, "y" : 1279 } } }, "connectors" : [ { "edgeId" : 149804, "type" : "CATALYST", "segments" : [ { "from" : { "x" : 1237, "y" : 1304 }, "to" : { "x" : 1239, "y" : 1331 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "c" : { "x" : 1239, "y" : 1335 }, "r" : 4, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1239, "y" : 1335 } } } ] }, { "id" : 149814, "reactomeId" : 113563, "displayName" : "NADP+", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 567, "y" : 365 }, "minX" : 524, "maxX" : 598, "minY" : 349, "maxY" : 398, "prop" : { "x" : 537, "y" : 350, "width" : 60, "height" : 30 }, "textPosition" : { "x" : 541, "y" : 354 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 592, "y" : 355 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 592, "y" : 355 } } }, "connectors" : [ { "edgeId" : 149810, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 547, "y" : 383 }, "to" : { "x" : 524, "y" : 398 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 543, "y" : 390 }, "b" : { "x" : 547, "y" : 383 }, "c" : { "x" : 539, "y" : 383 }, "type" : "ARROW", "centre" : { "x" : 539, "y" : 383 } } } ] }, { "id" : 149815, "reactomeId" : 11041871, "displayName" : "MECR dimer", "schemaClass" : "Complex", "renderableClass" : "Complex", "position" : { "x" : 492, "y" : 346 }, "minX" : 467, "maxX" : 524, "minY" : 323, "maxY" : 389, "prop" : { "x" : 467, "y" : 329, "width" : 51, "height" : 34 }, "textPosition" : { "x" : 469, "y" : 328 }, "bgColor" : { "r" : 204, "g" : 255, "b" : 255 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 518, "y" : 329 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 518, "y" : 329 } } }, "connectors" : [ { "edgeId" : 149810, "type" : "CATALYST", "segments" : [ { "from" : { "x" : 492, "y" : 366 }, "to" : { "x" : 492, "y" : 381 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "c" : { "x" : 493, "y" : 385 }, "r" : 4, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 493, "y" : 385 } } } ] }, { "id" : 149812, "reactomeId" : 113600, "displayName" : "NADPH", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 431, "y" : 341 }, "minX" : 402, "maxX" : 462, "minY" : 325, "maxY" : 396, "prop" : { "x" : 402, "y" : 326, "width" : 59, "height" : 30 }, "textPosition" : { "x" : 406, "y" : 330 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 456, "y" : 331 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 456, "y" : 331 } } }, "connectors" : [ { "edgeId" : 149810, "type" : "INPUT", "segments" : [ { "from" : { "x" : 438, "y" : 359 }, "to" : { "x" : 459, "y" : 396 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 149813, "reactomeId" : 77308, "displayName" : "DEC-CoA", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 584, "y" : 420 }, "minX" : 524, "maxX" : 624, "minY" : 398, "maxY" : 435, "prop" : { "x" : 546, "y" : 405, "width" : 77, "height" : 30 }, "textPosition" : { "x" : 554, "y" : 409 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 618, "y" : 410 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 618, "y" : 410 } } }, "connectors" : [ { "edgeId" : 149810, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 543, "y" : 405 }, "to" : { "x" : 524, "y" : 398 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 535, "y" : 406 }, "b" : { "x" : 543, "y" : 405 }, "c" : { "x" : 538, "y" : 399 }, "type" : "ARROW", "centre" : { "x" : 538, "y" : 399 } } } ] }, { "id" : 149818, "reactomeId" : 113521, "displayName" : "H2O", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 1003, "y" : 1312 }, "minX" : 920, "maxX" : 1026, "minY" : 1262, "maxY" : 1327, "prop" : { "x" : 982, "y" : 1297, "width" : 43, "height" : 30 }, "textPosition" : { "x" : 986, "y" : 1301 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1020, "y" : 1302 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1020, "y" : 1302 } } }, "connectors" : [ { "edgeId" : 149816, "type" : "INPUT", "segments" : [ { "from" : { "x" : 979, "y" : 1299 }, "to" : { "x" : 920, "y" : 1262 } } ], "stoichiometry" : { "value" : 1 } } ], "trivial" : true }, { "id" : 149819, "reactomeId" : 5690519, "displayName" : "MCFA, LCFA", "schemaClass" : "DefinedSet", "renderableClass" : "EntitySet", "position" : { "x" : 773, "y" : 1263 }, "minX" : 733, "maxX" : 855, "minY" : 1252, "maxY" : 1274, "prop" : { "x" : 733, "y" : 1252, "width" : 81, "height" : 22 }, "textPosition" : { "x" : 734, "y" : 1252 }, "connectors" : [ { "edgeId" : 149816, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 820, "y" : 1262 }, "to" : { "x" : 855, "y" : 1262 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 827, "y" : 1258 }, "b" : { "x" : 820, "y" : 1262 }, "c" : { "x" : 827, "y" : 1266 }, "type" : "ARROW", "centre" : { "x" : 827, "y" : 1266 } } } ] }, { "id" : 149817, "reactomeId" : 5690540, "displayName" : "MCFA-CoA, LCFA-CoA", "schemaClass" : "DefinedSet", "renderableClass" : "EntitySet", "position" : { "x" : 1019, "y" : 1263 }, "minX" : 920, "maxX" : 1067, "minY" : 1244, "maxY" : 1282, "prop" : { "x" : 971, "y" : 1244, "width" : 96, "height" : 38 }, "textPosition" : { "x" : 980, "y" : 1245 }, "connectors" : [ { "edgeId" : 149816, "type" : "INPUT", "segments" : [ { "from" : { "x" : 965, "y" : 1262 }, "to" : { "x" : 920, "y" : 1262 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 149822, "reactomeId" : 11028847, "displayName" : "ACOT2,9, THEM4,5 dimer", "schemaClass" : "DefinedSet", "renderableClass" : "EntitySet", "position" : { "x" : 886, "y" : 1329 }, "minX" : 837, "maxX" : 936, "minY" : 1270, "maxY" : 1354, "prop" : { "x" : 837, "y" : 1305, "width" : 99, "height" : 49 }, "textPosition" : { "x" : 852, "y" : 1305 }, "connectors" : [ { "edgeId" : 149816, "type" : "CATALYST", "segments" : [ { "from" : { "x" : 886, "y" : 1299 }, "to" : { "x" : 886, "y" : 1278 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "c" : { "x" : 886, "y" : 1274 }, "r" : 4, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 886, "y" : 1274 } } } ] }, { "id" : 149950, "reactomeId" : 5690542, "displayName" : "MCFA-CoA", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 1020, "y" : 1164 }, "minX" : 980, "maxX" : 1062, "minY" : 1148, "maxY" : 1179, "prop" : { "x" : 980, "y" : 1149, "width" : 81, "height" : 30 }, "textPosition" : { "x" : 986, "y" : 1153 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1056, "y" : 1154 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1056, "y" : 1154 } } }, "connectors" : [ ] }, { "id" : 149820, "reactomeId" : 29374, "displayName" : "CoA-SH", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 822, "y" : 1208 }, "minX" : 788, "maxX" : 857, "minY" : 1192, "maxY" : 1262, "prop" : { "x" : 788, "y" : 1193, "width" : 68, "height" : 30 }, "textPosition" : { "x" : 795, "y" : 1197 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 851, "y" : 1198 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 851, "y" : 1198 } } }, "connectors" : [ { "edgeId" : 149816, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 831, "y" : 1226 }, "to" : { "x" : 855, "y" : 1262 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 838, "y" : 1230 }, "b" : { "x" : 831, "y" : 1226 }, "c" : { "x" : 832, "y" : 1234 }, "type" : "ARROW", "centre" : { "x" : 832, "y" : 1234 } } } ] }, { "id" : 149948, "reactomeId" : 5690531, "displayName" : "MCFA", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 768, "y" : 1163 }, "minX" : 744, "maxX" : 794, "minY" : 1147, "maxY" : 1178, "prop" : { "x" : 744, "y" : 1148, "width" : 49, "height" : 30 }, "textPosition" : { "x" : 748, "y" : 1152 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 788, "y" : 1153 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 788, "y" : 1153 } } }, "connectors" : [ ] }, { "id" : 149821, "reactomeId" : 113529, "displayName" : "H+", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 801, "y" : 1310 }, "minX" : 784, "maxX" : 855, "minY" : 1262, "maxY" : 1325, "prop" : { "x" : 784, "y" : 1295, "width" : 34, "height" : 30 }, "textPosition" : { "x" : 787, "y" : 1299 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 813, "y" : 1300 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 813, "y" : 1300 } } }, "connectors" : [ { "edgeId" : 149816, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 817, "y" : 1292 }, "to" : { "x" : 855, "y" : 1262 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 820, "y" : 1285 }, "b" : { "x" : 817, "y" : 1292 }, "c" : { "x" : 825, "y" : 1291 }, "type" : "ARROW", "centre" : { "x" : 825, "y" : 1291 } } } ], "trivial" : true }, { "id" : 149826, "reactomeId" : 5690064, "displayName" : "MCFA, LCFA", "schemaClass" : "DefinedSet", "renderableClass" : "EntitySet", "position" : { "x" : 1935, "y" : 794 }, "minX" : 1833, "maxX" : 1974, "minY" : 783, "maxY" : 805, "prop" : { "x" : 1897, "y" : 783, "width" : 77, "height" : 22 }, "textPosition" : { "x" : 1911, "y" : 777 }, "connectors" : [ { "edgeId" : 149823, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 1891, "y" : 794 }, "to" : { "x" : 1833, "y" : 795 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 1884, "y" : 798 }, "b" : { "x" : 1891, "y" : 794 }, "c" : { "x" : 1884, "y" : 790 }, "type" : "ARROW", "centre" : { "x" : 1884, "y" : 790 } } } ] }, { "id" : 149954, "reactomeId" : 113559, "displayName" : "Ac-CoA", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 814, "y" : 903 }, "minX" : 780, "maxX" : 849, "minY" : 887, "maxY" : 918, "prop" : { "x" : 780, "y" : 888, "width" : 68, "height" : 30 }, "textPosition" : { "x" : 788, "y" : 892 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 843, "y" : 893 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 843, "y" : 893 } } }, "connectors" : [ ] }, { "id" : 149827, "reactomeId" : 76194, "displayName" : "CoA-SH", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 1911, "y" : 841 }, "minX" : 1833, "maxX" : 1943, "minY" : 795, "maxY" : 856, "prop" : { "x" : 1880, "y" : 826, "width" : 62, "height" : 30 }, "textPosition" : { "x" : 1884, "y" : 830 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1937, "y" : 831 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1937, "y" : 831 } } }, "connectors" : [ { "edgeId" : 149823, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 1885, "y" : 823 }, "to" : { "x" : 1833, "y" : 795 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 1877, "y" : 823 }, "b" : { "x" : 1885, "y" : 823 }, "c" : { "x" : 1881, "y" : 816 }, "type" : "ARROW", "centre" : { "x" : 1881, "y" : 816 } } } ] }, { "id" : 149955, "reactomeId" : 11048962, "displayName" : "Aerobic respiration and respiratory electron transport", "schemaClass" : "Pathway", "renderableClass" : "EncapsulatedNode", "position" : { "x" : 975, "y" : 904 }, "minX" : 903, "maxX" : 1047, "minY" : 873, "maxY" : 936, "prop" : { "x" : 903, "y" : 873, "width" : 144, "height" : 63 }, "textPosition" : { "x" : 905, "y" : 876 }, "connectors" : [ ] }, { "id" : 149824, "reactomeId" : 29356, "displayName" : "H2O", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 1709, "y" : 745 }, "minX" : 1688, "maxX" : 1739, "minY" : 729, "maxY" : 792, "prop" : { "x" : 1688, "y" : 730, "width" : 43, "height" : 30 }, "textPosition" : { "x" : 1692, "y" : 734 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1726, "y" : 735 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1726, "y" : 735 } } }, "connectors" : [ { "edgeId" : 149823, "type" : "INPUT", "segments" : [ { "from" : { "x" : 1718, "y" : 763 }, "to" : { "x" : 1739, "y" : 792 } } ], "stoichiometry" : { "value" : 1 } } ], "trivial" : true }, { "id" : 149825, "reactomeId" : 5690044, "displayName" : "MCFA-CoA, LCFA-CoA", "schemaClass" : "DefinedSet", "renderableClass" : "EntitySet", "position" : { "x" : 1661, "y" : 794 }, "minX" : 1619, "maxX" : 1739, "minY" : 776, "maxY" : 812, "prop" : { "x" : 1619, "y" : 776, "width" : 85, "height" : 36 }, "textPosition" : { "x" : 1623, "y" : 776 }, "connectors" : [ { "edgeId" : 149823, "type" : "INPUT", "segments" : [ { "from" : { "x" : 1710, "y" : 792 }, "to" : { "x" : 1739, "y" : 792 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 149831, "reactomeId" : 164991, "displayName" : "LCFA-CoA", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 1525, "y" : 794 }, "minX" : 1481, "maxX" : 1571, "minY" : 780, "maxY" : 840, "prop" : { "x" : 1481, "y" : 781, "width" : 89, "height" : 27 }, "textPosition" : { "x" : 1493, "y" : 784 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1565, "y" : 786 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1565, "y" : 786 } } }, "connectors" : [ { "edgeId" : 149830, "type" : "INPUT", "segments" : [ { "from" : { "x" : 1525, "y" : 811 }, "to" : { "x" : 1525, "y" : 840 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 149828, "reactomeId" : 70106, "displayName" : "H+", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 1889, "y" : 750 }, "minX" : 1833, "maxX" : 1908, "minY" : 734, "maxY" : 795, "prop" : { "x" : 1871, "y" : 735, "width" : 36, "height" : 31 }, "textPosition" : { "x" : 1875, "y" : 740 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1902, "y" : 740 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1902, "y" : 740 } } }, "connectors" : [ { "edgeId" : 149823, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 1868, "y" : 764 }, "to" : { "x" : 1833, "y" : 795 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 1865, "y" : 772 }, "b" : { "x" : 1868, "y" : 764 }, "c" : { "x" : 1860, "y" : 766 }, "type" : "ARROW", "centre" : { "x" : 1860, "y" : 766 } } } ], "trivial" : true }, { "id" : 149829, "reactomeId" : 11028818, "displayName" : "ACOT13 tetramer", "schemaClass" : "Complex", "renderableClass" : "Complex", "position" : { "x" : 1781, "y" : 856 }, "minX" : 1726, "maxX" : 1842, "minY" : 800, "maxY" : 874, "prop" : { "x" : 1726, "y" : 838, "width" : 110, "height" : 36 }, "textPosition" : { "x" : 1749, "y" : 838 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1836, "y" : 838 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1836, "y" : 838 } } }, "connectors" : [ { "edgeId" : 149823, "type" : "CATALYST", "segments" : [ { "from" : { "x" : 1781, "y" : 832 }, "to" : { "x" : 1781, "y" : 808 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "c" : { "x" : 1781, "y" : 804 }, "r" : 4, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1781, "y" : 804 } } } ] }, { "id" : 149835, "reactomeId" : 11037108, "displayName" : "DBI, (ACBD7)", "schemaClass" : "CandidateSet", "renderableClass" : "EntitySet", "position" : { "x" : 1546, "y" : 1093 }, "minX" : 1504, "maxX" : 1647, "minY" : 1071, "maxY" : 1104, "prop" : { "x" : 1504, "y" : 1082, "width" : 84, "height" : 22 }, "textPosition" : { "x" : 1516, "y" : 1076 }, "connectors" : [ { "edgeId" : 149834, "type" : "INPUT", "segments" : [ { "from" : { "x" : 1594, "y" : 1083 }, "to" : { "x" : 1647, "y" : 1071 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 149832, "reactomeId" : 11037117, "displayName" : "ACBD6", "schemaClass" : "EntityWithAccessionedSequence", "renderableClass" : "Protein", "position" : { "x" : 1466, "y" : 828 }, "minX" : 1442, "maxX" : 1525, "minY" : 811, "maxY" : 840, "prop" : { "x" : 1442, "y" : 817, "width" : 49, "height" : 22 }, "textPosition" : { "x" : 1442, "y" : 817 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1491, "y" : 817 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1491, "y" : 817 } } }, "connectors" : [ { "edgeId" : 149830, "type" : "INPUT", "segments" : [ { "from" : { "x" : 1494, "y" : 832 }, "to" : { "x" : 1525, "y" : 840 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 149833, "reactomeId" : 11037119, "displayName" : "ACBD6:LCFA-CoA", "schemaClass" : "Complex", "renderableClass" : "Complex", "position" : { "x" : 1526, "y" : 916 }, "minX" : 1471, "maxX" : 1588, "minY" : 899, "maxY" : 927, "prop" : { "x" : 1471, "y" : 905, "width" : 111, "height" : 22 }, "textPosition" : { "x" : 1471, "y" : 906 }, "bgColor" : { "r" : 204, "g" : 255, "b" : 255 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1582, "y" : 905 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1582, "y" : 905 } } }, "connectors" : [ { "edgeId" : 149830, "type" : "OUTPUT", "segments" : [ ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 149836, "reactomeId" : 8848288, "displayName" : "MCFA-CoA, LCFA-CoA", "schemaClass" : "DefinedSet", "renderableClass" : "EntitySet", "position" : { "x" : 1541, "y" : 1036 }, "minX" : 1483, "maxX" : 1647, "minY" : 1018, "maxY" : 1071, "prop" : { "x" : 1483, "y" : 1018, "width" : 117, "height" : 36 }, "textPosition" : { "x" : 1486, "y" : 1018 }, "connectors" : [ { "edgeId" : 149834, "type" : "INPUT", "segments" : [ { "from" : { "x" : 1595, "y" : 1060 }, "to" : { "x" : 1647, "y" : 1071 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 149837, "reactomeId" : 11037110, "displayName" : "DBI,ACBD7:MCFA-CoA,LCFA-CoA", "schemaClass" : "Complex", "renderableClass" : "Complex", "position" : { "x" : 1781, "y" : 1074 }, "minX" : 1723, "maxX" : 1845, "minY" : 1050, "maxY" : 1092, "prop" : { "x" : 1723, "y" : 1056, "width" : 116, "height" : 36 }, "textPosition" : { "x" : 1724, "y" : 1057 }, "bgColor" : { "r" : 204, "g" : 255, "b" : 255 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1839, "y" : 1056 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1839, "y" : 1056 } } }, "connectors" : [ { "edgeId" : 149834, "type" : "OUTPUT", "segments" : [ ], "stoichiometry" : { "value" : 1 } } ] } ], "edges" : [ { "id" : 149792, "reactomeId" : 10998662, "displayName" : "propionyl-CoA + CO2 + ATP <=> D-methylmalonyl-CoA + ADP + orthophosphate", "schemaClass" : "Reaction", "renderableClass" : "Reaction", "position" : { "x" : 1273, "y" : 797 }, "minX" : 1267, "maxX" : 1279, "minY" : 775, "maxY" : 834, "reactionType" : "transition", "segments" : [ { "from" : { "x" : 1272, "y" : 775 }, "to" : { "x" : 1273, "y" : 797 } }, { "from" : { "x" : 1273, "y" : 797 }, "to" : { "x" : 1273, "y" : 834 } } ], "reactionShape" : { "a" : { "x" : 1267, "y" : 791 }, "b" : { "x" : 1279, "y" : 803 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 1273, "y" : 797 } }, "inputs" : [ { "id" : 149793, "points" : [ { "x" : 1272, "y" : 752 } ] }, { "id" : 149794, "points" : [ { "x" : 1235, "y" : 766 } ] }, { "id" : 149795, "points" : [ { "x" : 1298, "y" : 770 } ] } ], "outputs" : [ { "id" : 149796, "points" : [ { "x" : 1273, "y" : 871 } ] }, { "id" : 149797, "points" : [ { "x" : 1237, "y" : 845 } ] }, { "id" : 149798, "points" : [ { "x" : 1311, "y" : 855 } ] }, { "id" : 149799, "points" : [ { "x" : 1304, "y" : 826 } ] } ], "catalysts" : [ { "id" : 149800, "points" : [ { "x" : 1243, "y" : 796 } ] } ] }, { "id" : 149830, "reactomeId" : 11037121, "displayName" : "ACBD6 binds LCFA-CoA", "schemaClass" : "Reaction", "renderableClass" : "Reaction", "position" : { "x" : 1525, "y" : 865 }, "minX" : 1519, "maxX" : 1531, "minY" : 840, "maxY" : 902, "reactionType" : "binding", "segments" : [ { "from" : { "x" : 1525, "y" : 840 }, "to" : { "x" : 1525, "y" : 865 } }, { "from" : { "x" : 1525, "y" : 865 }, "to" : { "x" : 1525, "y" : 902 } } ], "endShape" : { "a" : { "x" : 1521, "y" : 895 }, "b" : { "x" : 1525, "y" : 902 }, "c" : { "x" : 1529, "y" : 895 }, "type" : "ARROW", "centre" : { "x" : 1529, "y" : 895 } }, "reactionShape" : { "c" : { "x" : 1525, "y" : 865 }, "r" : 5, "type" : "CIRCLE", "centre" : { "x" : 1525, "y" : 865 } }, "inputs" : [ { "id" : 149831, "points" : [ { "x" : 1525, "y" : 811 } ] }, { "id" : 149832, "points" : [ { "x" : 1494, "y" : 832 } ] } ], "outputs" : [ { "id" : 149833 } ] }, { "id" : 149767, "reactomeId" : 11001790, "displayName" : "2-trans-Dodecenoyl-CoA+H2O =>( S)-3-Hydroxydodecanoyl-CoA", "schemaClass" : "Reaction", "renderableClass" : "Reaction", "position" : { "x" : 1047, "y" : 361 }, "minX" : 1041, "maxX" : 1053, "minY" : 338, "maxY" : 395, "reactionType" : "transition", "segments" : [ { "from" : { "x" : 1046, "y" : 338 }, "to" : { "x" : 1047, "y" : 361 } }, { "from" : { "x" : 1047, "y" : 361 }, "to" : { "x" : 1044, "y" : 395 } } ], "endShape" : { "a" : { "x" : 1041, "y" : 388 }, "b" : { "x" : 1044, "y" : 395 }, "c" : { "x" : 1049, "y" : 388 }, "type" : "ARROW", "centre" : { "x" : 1049, "y" : 388 } }, "reactionShape" : { "a" : { "x" : 1041, "y" : 355 }, "b" : { "x" : 1053, "y" : 367 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 1047, "y" : 361 } }, "inputs" : [ { "id" : 149768, "points" : [ { "x" : 1046, "y" : 321 } ] }, { "id" : 149769, "points" : [ { "x" : 1124, "y" : 313 } ] } ], "outputs" : [ { "id" : 149770 } ], "catalysts" : [ { "id" : 149771, "points" : [ { "x" : 1078, "y" : 359 } ] } ] }, { "id" : 149834, "reactomeId" : 11037112, "displayName" : "DBI, ACBD7 bind MCFA-CoA and LCFA-CoA", "schemaClass" : "Reaction", "renderableClass" : "Reaction", "position" : { "x" : 1677, "y" : 1071 }, "minX" : 1647, "maxX" : 1720, "minY" : 1065, "maxY" : 1077, "reactionType" : "binding", "segments" : [ { "from" : { "x" : 1647, "y" : 1071 }, "to" : { "x" : 1677, "y" : 1071 } }, { "from" : { "x" : 1677, "y" : 1071 }, "to" : { "x" : 1720, "y" : 1072 } } ], "endShape" : { "a" : { "x" : 1713, "y" : 1076 }, "b" : { "x" : 1720, "y" : 1072 }, "c" : { "x" : 1713, "y" : 1068 }, "type" : "ARROW", "centre" : { "x" : 1713, "y" : 1068 } }, "reactionShape" : { "c" : { "x" : 1677, "y" : 1071 }, "r" : 5, "type" : "CIRCLE", "centre" : { "x" : 1677, "y" : 1071 } }, "inputs" : [ { "id" : 149835, "points" : [ { "x" : 1594, "y" : 1083 } ] }, { "id" : 149836, "points" : [ { "x" : 1595, "y" : 1060 } ] } ], "outputs" : [ { "id" : 149837 } ] }, { "id" : 149801, "reactomeId" : 10998644, "displayName" : "D-methylmalonyl-CoA <=> L-methylmalonyl-CoA", "schemaClass" : "Reaction", "renderableClass" : "Reaction", "position" : { "x" : 1273, "y" : 932 }, "minX" : 1267, "maxX" : 1279, "minY" : 907, "maxY" : 968, "reactionType" : "transition", "segments" : [ { "from" : { "x" : 1273, "y" : 907 }, "to" : { "x" : 1273, "y" : 932 } }, { "from" : { "x" : 1273, "y" : 932 }, "to" : { "x" : 1273, "y" : 968 } } ], "endShape" : { "a" : { "x" : 1269, "y" : 961 }, "b" : { "x" : 1273, "y" : 968 }, "c" : { "x" : 1277, "y" : 961 }, "type" : "ARROW", "centre" : { "x" : 1277, "y" : 961 } }, "reactionShape" : { "a" : { "x" : 1267, "y" : 926 }, "b" : { "x" : 1279, "y" : 938 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 1273, "y" : 932 } }, "inputs" : [ { "id" : 149796 } ], "outputs" : [ { "id" : 149802 } ], "catalysts" : [ { "id" : 149803, "points" : [ { "x" : 1234, "y" : 933 } ] } ] }, { "id" : 149772, "reactomeId" : 11001798, "displayName" : "trans-Dec-2-enoyl-CoA+H2O => (S)-Hydroxydecanoyl-CoA", "schemaClass" : "Reaction", "renderableClass" : "Reaction", "position" : { "x" : 308, "y" : 412 }, "minX" : 283, "maxX" : 325, "minY" : 406, "maxY" : 418, "reactionType" : "transition", "segments" : [ { "from" : { "x" : 325, "y" : 412 }, "to" : { "x" : 308, "y" : 412 } }, { "from" : { "x" : 308, "y" : 412 }, "to" : { "x" : 283, "y" : 412 } } ], "endShape" : { "a" : { "x" : 290, "y" : 408 }, "b" : { "x" : 283, "y" : 412 }, "c" : { "x" : 290, "y" : 416 }, "type" : "ARROW", "centre" : { "x" : 290, "y" : 416 } }, "reactionShape" : { "a" : { "x" : 302, "y" : 406 }, "b" : { "x" : 314, "y" : 418 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 308, "y" : 412 } }, "inputs" : [ { "id" : 149773, "points" : [ { "x" : 362, "y" : 413 } ] }, { "id" : 149774, "points" : [ { "x" : 330, "y" : 421 } ] } ], "outputs" : [ { "id" : 149775 } ], "catalysts" : [ { "id" : 149776, "points" : [ { "x" : 308, "y" : 375 } ] } ] }, { "id" : 149804, "reactomeId" : 11040865, "displayName" : "MCAT transfers Mal from Mal-CoA to NDUFAB1", "schemaClass" : "Reaction", "renderableClass" : "Reaction", "position" : { "x" : 1240, "y" : 1347 }, "minX" : 1213, "maxX" : 1275, "minY" : 1341, "maxY" : 1353, "reactionType" : "transition", "segments" : [ { "from" : { "x" : 1213, "y" : 1346 }, "to" : { "x" : 1240, "y" : 1347 } }, { "from" : { "x" : 1240, "y" : 1347 }, "to" : { "x" : 1275, "y" : 1347 } } ], "reactionShape" : { "a" : { "x" : 1234, "y" : 1341 }, "b" : { "x" : 1246, "y" : 1353 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 1240, "y" : 1347 } }, "inputs" : [ { "id" : 149805, "points" : [ { "x" : 1189, "y" : 1339 } ] }, { "id" : 149806, "points" : [ { "x" : 1180, "y" : 1379 } ] } ], "outputs" : [ { "id" : 149807, "points" : [ { "x" : 1301, "y" : 1375 } ] }, { "id" : 149808, "points" : [ { "x" : 1302, "y" : 1328 } ] } ], "catalysts" : [ { "id" : 149809, "points" : [ { "x" : 1237, "y" : 1304 } ] } ] }, { "id" : 149810, "reactomeId" : 11041874, "displayName" : "MECR dimer reduces tdec2-CoA to DEC-CoA", "schemaClass" : "Reaction", "renderableClass" : "Reaction", "position" : { "x" : 493, "y" : 397 }, "minX" : 459, "maxX" : 524, "minY" : 391, "maxY" : 403, "reactionType" : "transition", "segments" : [ { "from" : { "x" : 459, "y" : 396 }, "to" : { "x" : 493, "y" : 397 } }, { "from" : { "x" : 493, "y" : 397 }, "to" : { "x" : 524, "y" : 398 } } ], "reactionShape" : { "a" : { "x" : 487, "y" : 391 }, "b" : { "x" : 499, "y" : 403 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 493, "y" : 397 } }, "inputs" : [ { "id" : 149773, "points" : [ { "x" : 427, "y" : 405 } ] }, { "id" : 149811, "points" : [ { "x" : 433, "y" : 382 } ] }, { "id" : 149812, "points" : [ { "x" : 438, "y" : 359 } ] } ], "outputs" : [ { "id" : 149813, "points" : [ { "x" : 543, "y" : 405 } ] }, { "id" : 149814, "points" : [ { "x" : 547, "y" : 383 } ] } ], "catalysts" : [ { "id" : 149815, "points" : [ { "x" : 492, "y" : 366 } ] } ] }, { "id" : 149777, "reactomeId" : 11001796, "displayName" : "trans-Oct-2-enoyl-CoA+H2O => (S)-Hydroxyoctanoyl-CoA", "schemaClass" : "Reaction", "renderableClass" : "Reaction", "position" : { "x" : 687, "y" : 556 }, "minX" : 668, "maxX" : 720, "minY" : 550, "maxY" : 562, "reactionType" : "transition", "segments" : [ { "from" : { "x" : 668, "y" : 557 }, "to" : { "x" : 687, "y" : 556 } }, { "from" : { "x" : 687, "y" : 556 }, "to" : { "x" : 720, "y" : 556 } } ], "endShape" : { "a" : { "x" : 713, "y" : 560 }, "b" : { "x" : 720, "y" : 556 }, "c" : { "x" : 713, "y" : 552 }, "type" : "ARROW", "centre" : { "x" : 713, "y" : 552 } }, "reactionShape" : { "a" : { "x" : 681, "y" : 550 }, "b" : { "x" : 693, "y" : 562 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 687, "y" : 556 } }, "inputs" : [ { "id" : 149778, "points" : [ { "x" : 659, "y" : 557 } ] }, { "id" : 149779, "points" : [ { "x" : 666, "y" : 583 } ] } ], "outputs" : [ { "id" : 149780 } ], "catalysts" : [ { "id" : 149781, "points" : [ { "x" : 683, "y" : 514 } ] } ] }, { "id" : 149782, "reactomeId" : 11001794, "displayName" : "trans-Hex-2-enoyl-CoA+H2O<=>(S)-Hydroxyhexanoyl-CoA", "schemaClass" : "Reaction", "renderableClass" : "Reaction", "position" : { "x" : 750, "y" : 715 }, "minX" : 728, "maxX" : 769, "minY" : 709, "maxY" : 721, "reactionType" : "transition", "segments" : [ { "from" : { "x" : 769, "y" : 713 }, "to" : { "x" : 750, "y" : 715 } }, { "from" : { "x" : 750, "y" : 715 }, "to" : { "x" : 728, "y" : 715 } } ], "endShape" : { "a" : { "x" : 735, "y" : 711 }, "b" : { "x" : 728, "y" : 715 }, "c" : { "x" : 735, "y" : 719 }, "type" : "ARROW", "centre" : { "x" : 735, "y" : 719 } }, "reactionShape" : { "a" : { "x" : 744, "y" : 709 }, "b" : { "x" : 756, "y" : 721 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 750, "y" : 715 } }, "inputs" : [ { "id" : 149783, "points" : [ { "x" : 784, "y" : 713 } ] }, { "id" : 149784, "points" : [ { "x" : 778, "y" : 687 } ] } ], "outputs" : [ { "id" : 149785 } ], "catalysts" : [ { "id" : 149786, "points" : [ { "x" : 752, "y" : 741 } ] } ] }, { "id" : 149787, "reactomeId" : 11001792, "displayName" : "Crotonoyl-CoA+H2O => (S)-3-Hydroxybutanoyl-CoA", "schemaClass" : "Reaction", "renderableClass" : "Reaction", "position" : { "x" : 407, "y" : 829 }, "minX" : 389, "maxX" : 436, "minY" : 823, "maxY" : 835, "reactionType" : "transition", "segments" : [ { "from" : { "x" : 389, "y" : 829 }, "to" : { "x" : 407, "y" : 829 } }, { "from" : { "x" : 407, "y" : 829 }, "to" : { "x" : 436, "y" : 829 } } ], "endShape" : { "a" : { "x" : 429, "y" : 833 }, "b" : { "x" : 436, "y" : 829 }, "c" : { "x" : 429, "y" : 825 }, "type" : "ARROW", "centre" : { "x" : 429, "y" : 825 } }, "reactionShape" : { "a" : { "x" : 401, "y" : 823 }, "b" : { "x" : 413, "y" : 835 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 407, "y" : 829 } }, "inputs" : [ { "id" : 149788, "points" : [ { "x" : 387, "y" : 855 } ] }, { "id" : 149789, "points" : [ { "x" : 377, "y" : 830 } ] } ], "outputs" : [ { "id" : 149790 } ], "catalysts" : [ { "id" : 149791, "points" : [ { "x" : 417, "y" : 784 } ] } ] }, { "id" : 149816, "reactomeId" : 11028850, "displayName" : "ACOT2,9,THEM4,5 hydrolyse MCFA-CoA, LCFA-CoA", "schemaClass" : "Reaction", "renderableClass" : "Reaction", "position" : { "x" : 886, "y" : 1262 }, "minX" : 855, "maxX" : 920, "minY" : 1256, "maxY" : 1268, "reactionType" : "transition", "segments" : [ { "from" : { "x" : 920, "y" : 1262 }, "to" : { "x" : 886, "y" : 1262 } }, { "from" : { "x" : 886, "y" : 1262 }, "to" : { "x" : 855, "y" : 1262 } } ], "reactionShape" : { "a" : { "x" : 880, "y" : 1256 }, "b" : { "x" : 892, "y" : 1268 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 886, "y" : 1262 } }, "inputs" : [ { "id" : 149817, "points" : [ { "x" : 965, "y" : 1262 } ] }, { "id" : 149818, "points" : [ { "x" : 979, "y" : 1299 } ] } ], "outputs" : [ { "id" : 149819, "points" : [ { "x" : 820, "y" : 1262 } ] }, { "id" : 149820, "points" : [ { "x" : 831, "y" : 1226 } ] }, { "id" : 149821, "points" : [ { "x" : 817, "y" : 1292 } ] } ], "catalysts" : [ { "id" : 149822, "points" : [ { "x" : 886, "y" : 1299 } ] } ] }, { "id" : 149823, "reactomeId" : 11028821, "displayName" : "Cytosolic ACOTs hydrolyse MCFA-CoA, LCFA-CoA", "schemaClass" : "Reaction", "renderableClass" : "Reaction", "position" : { "x" : 1781, "y" : 792 }, "minX" : 1739, "maxX" : 1833, "minY" : 786, "maxY" : 798, "reactionType" : "transition", "segments" : [ { "from" : { "x" : 1739, "y" : 792 }, "to" : { "x" : 1781, "y" : 792 } }, { "from" : { "x" : 1781, "y" : 792 }, "to" : { "x" : 1833, "y" : 795 } } ], "reactionShape" : { "a" : { "x" : 1775, "y" : 786 }, "b" : { "x" : 1787, "y" : 798 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 1781, "y" : 792 } }, "inputs" : [ { "id" : 149824, "points" : [ { "x" : 1718, "y" : 763 } ] }, { "id" : 149825, "points" : [ { "x" : 1710, "y" : 792 } ] } ], "outputs" : [ { "id" : 149826, "points" : [ { "x" : 1891, "y" : 794 } ] }, { "id" : 149827, "points" : [ { "x" : 1885, "y" : 823 } ] }, { "id" : 149828, "points" : [ { "x" : 1868, "y" : 764 } ] } ], "catalysts" : [ { "id" : 149829, "points" : [ { "x" : 1781, "y" : 832 } ] } ] } ], "compartments" : [ { "id" : 149953, "reactomeId" : 17957, "displayName" : "endoplasmic reticulum lumen", "schemaClass" : "Compartment", "renderableClass" : "Compartment", "position" : { "x" : 1696, "y" : 1087 }, "minX" : 1446, "maxX" : 1947, "minY" : 984, "maxY" : 1191, "prop" : { "x" : 1446, "y" : 984, "width" : 501, "height" : 207 }, "textPosition" : { "x" : 1460, "y" : 1144 }, "insets" : { "x" : 1456, "y" : 994, "width" : 481, "height" : 187 }, "bgColor" : { "r" : 250, "g" : 240, "b" : 240 }, "componentIds" : [ 149834, 149835, 149836, 149837 ] }, { "id" : 149947, "reactomeId" : 70101, "displayName" : "cytosol", "schemaClass" : "Compartment", "renderableClass" : "Compartment", "position" : { "x" : 1039, "y" : 740 }, "minX" : 0, "maxX" : 2078, "minY" : 0, "maxY" : 1480, "prop" : { "x" : 0, "y" : 0, "width" : 2078, "height" : 1480 }, "textPosition" : { "x" : 73, "y" : 1432 }, "insets" : { "x" : 10, "y" : 10, "width" : 2058, "height" : 1460 }, "bgColor" : { "r" : 250, "g" : 240, "b" : 240 }, "componentIds" : [ 149838, 149823, 149825, 149826, 149827, 149829, 149830, 149831, 149966, 149832, 149833, 149953, 149824, 149828 ] }, { "id" : 149838, "reactomeId" : 5460, "displayName" : "mitochondrial matrix", "schemaClass" : "Compartment", "renderableClass" : "Compartment", "position" : { "x" : 714, "y" : 717 }, "minX" : 46, "maxX" : 1382, "minY" : 37, "maxY" : 1398, "prop" : { "x" : 46, "y" : 37, "width" : 1336, "height" : 1361 }, "textPosition" : { "x" : 67, "y" : 1341 }, "insets" : { "x" : 56, "y" : 47, "width" : 1316, "height" : 1341 }, "bgColor" : { "r" : 250, "g" : 240, "b" : 240 }, "componentIds" : [ 149768, 149767, 149769, 149770, 149771, 149813, 149773, 149772, 149774, 149775, 149776, 149778, 149777, 149779, 149780, 149781, 149783, 149782, 149784, 149785, 149786, 149789, 149787, 149788, 149790, 149791, 149932, 149792, 149793, 149798, 149796, 149800, 149801, 149802, 149803, 149804, 149805, 149809, 149808, 149810, 149815, 149811, 149812, 149814, 149948, 149950, 149820, 149816, 149817, 149964, 149818, 149819, 149965, 149822, 149807, 149954, 149955, 149967, 149968, 149806, 149795, 149794, 149797, 149799, 149821 ] } ], "notes" : [ ], "links" : [ { "id" : 149968, "renderableClass" : "Interaction", "position" : { "x" : 1156, "y" : 1076 }, "minX" : 1008, "maxX" : 1230, "minY" : 939, "maxY" : 1082, "interactionType" : "Activate", "segments" : [ { "from" : { "x" : 1230, "y" : 1076 }, "to" : { "x" : 1156, "y" : 1076 } }, { "from" : { "x" : 1156, "y" : 1076 }, "to" : { "x" : 1008, "y" : 939 } } ], "endShape" : { "a" : { "x" : 1016, "y" : 941 }, "b" : { "x" : 1008, "y" : 939 }, "c" : { "x" : 1010, "y" : 947 }, "type" : "ARROW", "empty" : true, "centre" : { "x" : 1010, "y" : 947 } }, "reactionShape" : { "a" : { "x" : 1150, "y" : 1070 }, "b" : { "x" : 1162, "y" : 1082 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 1156, "y" : 1076 } }, "inputs" : [ { "id" : 149932 } ], "outputs" : [ { "id" : 149955 } ] }, { "id" : 149966, "renderableClass" : "EntitySetAndMemberLink", "position" : { "x" : 1593, "y" : 794 }, "minX" : 1573, "maxX" : 1613, "minY" : 788, "maxY" : 800, "segments" : [ { "from" : { "x" : 1573, "y" : 794 }, "to" : { "x" : 1613, "y" : 794 } } ], "reactionShape" : { "a" : { "x" : 1587, "y" : 788 }, "b" : { "x" : 1599, "y" : 800 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 1593, "y" : 794 } }, "inputs" : [ { "id" : 149831 } ], "outputs" : [ { "id" : 149825 } ] }, { "id" : 149967, "renderableClass" : "Interaction", "position" : { "x" : 875, "y" : 903 }, "minX" : 851, "maxX" : 900, "minY" : 897, "maxY" : 909, "interactionType" : "Activate", "segments" : [ { "from" : { "x" : 851, "y" : 903 }, "to" : { "x" : 900, "y" : 903 } } ], "endShape" : { "a" : { "x" : 893, "y" : 907 }, "b" : { "x" : 900, "y" : 903 }, "c" : { "x" : 893, "y" : 899 }, "type" : "ARROW", "empty" : true, "centre" : { "x" : 893, "y" : 899 } }, "reactionShape" : { "a" : { "x" : 869, "y" : 897 }, "b" : { "x" : 881, "y" : 909 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 875, "y" : 903 } }, "inputs" : [ { "id" : 149954 } ], "outputs" : [ { "id" : 149955 } ] }, { "id" : 149964, "renderableClass" : "EntitySetAndMemberLink", "position" : { "x" : 1019, "y" : 1210 }, "minX" : 1013, "maxX" : 1025, "minY" : 1182, "maxY" : 1238, "segments" : [ { "from" : { "x" : 1019, "y" : 1182 }, "to" : { "x" : 1019, "y" : 1238 } } ], "reactionShape" : { "a" : { "x" : 1013, "y" : 1204 }, "b" : { "x" : 1025, "y" : 1216 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 1019, "y" : 1210 } }, "inputs" : [ { "id" : 149950 } ], "outputs" : [ { "id" : 149817 } ] }, { "id" : 149965, "renderableClass" : "EntitySetAndMemberLink", "position" : { "x" : 770, "y" : 1213 }, "minX" : 764, "maxX" : 776, "minY" : 1181, "maxY" : 1246, "segments" : [ { "from" : { "x" : 768, "y" : 1181 }, "to" : { "x" : 772, "y" : 1246 } } ], "reactionShape" : { "a" : { "x" : 764, "y" : 1207 }, "b" : { "x" : 776, "y" : 1219 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 770, "y" : 1213 } }, "inputs" : [ { "id" : 149948 } ], "outputs" : [ { "id" : 149819 } ] } ], "shadows" : [ { "id" : 149970, "reactomeId" : 11049184, "displayName" : "mitochondrial fatty acid beta-oxidation of saturated fatty acids", "schemaClass" : "Pathway", "renderableClass" : "Shadow", "position" : { "x" : 656, "y" : 581 }, "minX" : 134, "maxX" : 1179, "minY" : 264, "maxY" : 898, "prop" : { "x" : 134, "y" : 264, "width" : 1045, "height" : 445 }, "points" : [ { "x" : 134, "y" : 264 }, { "x" : 1179, "y" : 264 }, { "x" : 1179, "y" : 898 }, { "x" : 134, "y" : 898 } ], "colour" : "#dc3912" }, { "id" : 149969, "reactomeId" : 11048990, "displayName" : "Propionyl-CoA catabolism", "schemaClass" : "Pathway", "renderableClass" : "Shadow", "position" : { "x" : 1236, "y" : 860 }, "minX" : 1104, "maxX" : 1369, "minY" : 709, "maxY" : 1011, "prop" : { "x" : 1179, "y" : 709, "width" : 190, "height" : 189 }, "points" : [ { "x" : 1104, "y" : 709 }, { "x" : 1369, "y" : 709 }, { "x" : 1369, "y" : 1011 }, { "x" : 1104, "y" : 1011 } ], "colour" : "#4684ee" } ], "minX" : 0, "maxX" : 2078, "minY" : 0, "maxY" : 1480, "disease" : false }