{
  "dbId" : 10996011,
  "stableId" : "R-CEL-9686114",
  "displayName" : "Non-canonical inflammasome activation",
  "nodes" : [ {
    "id" : 88224,
    "reactomeId" : 10988415,
    "displayName" : "Homologues of SERPINB1",
    "schemaClass" : "DefinedSet",
    "renderableClass" : "EntitySet",
    "position" : {
      "x" : 193,
      "y" : 446
    },
    "minX" : 161,
    "maxX" : 225,
    "minY" : 435,
    "maxY" : 473,
    "prop" : {
      "x" : 161,
      "y" : 435,
      "width" : 64,
      "height" : 23
    },
    "textPosition" : {
      "x" : 161,
      "y" : 415
    },
    "connectors" : [ {
      "edgeId" : 88223,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 199,
          "y" : 461
        },
        "to" : {
          "x" : 209,
          "y" : 473
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 88227,
    "reactomeId" : 10988391,
    "displayName" : "CASP5(1-434):LPS micelles",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 242,
      "y" : 386
    },
    "minX" : 182,
    "maxX" : 308,
    "minY" : 352,
    "maxY" : 405,
    "prop" : {
      "x" : 182,
      "y" : 368,
      "width" : 120,
      "height" : 37
    },
    "textPosition" : {
      "x" : 180,
      "y" : 370
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 302,
          "y" : 368
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 302,
          "y" : 368
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 88225,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 88228,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 257,
          "y" : 365
        },
        "to" : {
          "x" : 271,
          "y" : 352
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 88226,
    "reactomeId" : 10988389,
    "displayName" : "ced-3",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 84,
      "y" : 353
    },
    "minX" : 38,
    "maxX" : 271,
    "minY" : 336,
    "maxY" : 385,
    "prop" : {
      "x" : 38,
      "y" : 342,
      "width" : 93,
      "height" : 23
    },
    "textPosition" : {
      "x" : 63,
      "y" : 343
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 131,
          "y" : 342
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 131,
          "y" : 342
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 88225,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 96,
          "y" : 368
        },
        "to" : {
          "x" : 118,
          "y" : 385
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 88228,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 134,
          "y" : 352
        },
        "to" : {
          "x" : 271,
          "y" : 352
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 88229,
    "reactomeId" : 10992846,
    "displayName" : "2xCASP5:LPS micelles",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 367,
      "y" : 352
    },
    "minX" : 323,
    "maxX" : 448,
    "minY" : 328,
    "maxY" : 371,
    "prop" : {
      "x" : 323,
      "y" : 334,
      "width" : 88,
      "height" : 37
    },
    "textPosition" : {
      "x" : 321,
      "y" : 336
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 411,
          "y" : 334
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 411,
          "y" : 334
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 88228,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 88230,
      "type" : "INPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 88230,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 414,
          "y" : 338
        },
        "to" : {
          "x" : 444,
          "y" : 328
        }
      }, {
        "from" : {
          "x" : 444,
          "y" : 328
        },
        "to" : {
          "x" : 444,
          "y" : 335
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 444,
          "y" : 339
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 444,
          "y" : 339
        }
      }
    } ]
  }, {
    "id" : 88231,
    "reactomeId" : 10992854,
    "displayName" : "activated CASP5",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 558,
      "y" : 352
    },
    "minX" : 473,
    "maxX" : 615,
    "minY" : 335,
    "maxY" : 364,
    "prop" : {
      "x" : 507,
      "y" : 341,
      "width" : 102,
      "height" : 23
    },
    "textPosition" : {
      "x" : 523,
      "y" : 329
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 609,
          "y" : 341
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 609,
          "y" : 341
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 88230,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 504,
          "y" : 351
        },
        "to" : {
          "x" : 473,
          "y" : 351
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 497,
          "y" : 355
        },
        "b" : {
          "x" : 504,
          "y" : 351
        },
        "c" : {
          "x" : 497,
          "y" : 347
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 497,
          "y" : 347
        }
      }
    } ]
  }, {
    "id" : 88233,
    "reactomeId" : 10993925,
    "displayName" : "Pyroptosis",
    "schemaClass" : "Pathway",
    "renderableClass" : "EncapsulatedNode",
    "position" : {
      "x" : 313,
      "y" : 44
    },
    "minX" : 275,
    "maxX" : 351,
    "minY" : 29,
    "maxY" : 60,
    "prop" : {
      "x" : 275,
      "y" : 29,
      "width" : 76,
      "height" : 31
    },
    "textPosition" : {
      "x" : 276,
      "y" : 23
    },
    "connectors" : [ ]
  }, {
    "id" : 88217,
    "reactomeId" : 9686105,
    "displayName" : "LPS micelles",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 89,
      "y" : 421
    },
    "minX" : 46,
    "maxX" : 475,
    "minY" : 351,
    "maxY" : 507,
    "prop" : {
      "x" : 46,
      "y" : 406,
      "width" : 86,
      "height" : 31
    },
    "textPosition" : {
      "x" : 47,
      "y" : 411
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 127,
          "y" : 411
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 127,
          "y" : 411
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 88225,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 101,
          "y" : 403
        },
        "to" : {
          "x" : 118,
          "y" : 385
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 88230,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 135,
          "y" : 419
        },
        "to" : {
          "x" : 475,
          "y" : 404
        }
      }, {
        "from" : {
          "x" : 475,
          "y" : 404
        },
        "to" : {
          "x" : 473,
          "y" : 351
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 142,
          "y" : 415
        },
        "b" : {
          "x" : 135,
          "y" : 419
        },
        "c" : {
          "x" : 142,
          "y" : 423
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 142,
          "y" : 423
        }
      }
    }, {
      "edgeId" : 88216,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 108,
          "y" : 440
        },
        "to" : {
          "x" : 199,
          "y" : 507
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 88219,
    "reactomeId" : 10988385,
    "displayName" : "CASP4:LPS micelles",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 309,
      "y" : 511
    },
    "minX" : 250,
    "maxX" : 375,
    "minY" : 494,
    "maxY" : 547,
    "prop" : {
      "x" : 250,
      "y" : 500,
      "width" : 119,
      "height" : 23
    },
    "textPosition" : {
      "x" : 270,
      "y" : 488
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 369,
          "y" : 500
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 369,
          "y" : 500
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 88216,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 88220,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 323,
          "y" : 526
        },
        "to" : {
          "x" : 355,
          "y" : 547
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 88218,
    "reactomeId" : 10988383,
    "displayName" : "ced-3",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 93,
      "y" : 550
    },
    "minX" : 48,
    "maxX" : 355,
    "minY" : 473,
    "maxY" : 562,
    "prop" : {
      "x" : 48,
      "y" : 539,
      "width" : 90,
      "height" : 23
    },
    "textPosition" : {
      "x" : 71,
      "y" : 540
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 138,
          "y" : 539
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 138,
          "y" : 539
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 88216,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 121,
          "y" : 536
        },
        "to" : {
          "x" : 199,
          "y" : 507
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 88220,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 141,
          "y" : 549
        },
        "to" : {
          "x" : 355,
          "y" : 547
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 88223,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 110,
          "y" : 536
        },
        "to" : {
          "x" : 209,
          "y" : 473
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 88221,
    "reactomeId" : 10988395,
    "displayName" : "2xCASP4:LPS micelles",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 505,
      "y" : 549
    },
    "minX" : 461,
    "maxX" : 555,
    "minY" : 525,
    "maxY" : 568,
    "prop" : {
      "x" : 461,
      "y" : 531,
      "width" : 88,
      "height" : 37
    },
    "textPosition" : {
      "x" : 459,
      "y" : 533
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 549,
          "y" : 531
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 549,
          "y" : 531
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 88220,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 88222,
    "reactomeId" : 10988417,
    "displayName" : "CASP4:SERPINB1",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 417,
      "y" : 473
    },
    "minX" : 365,
    "maxX" : 476,
    "minY" : 456,
    "maxY" : 538,
    "prop" : {
      "x" : 365,
      "y" : 462,
      "width" : 105,
      "height" : 23
    },
    "textPosition" : {
      "x" : 383,
      "y" : 450
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 470,
          "y" : 462
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 470,
          "y" : 462
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 88220,
      "type" : "INHIBITOR",
      "segments" : [ {
        "from" : {
          "x" : 408,
          "y" : 488
        },
        "to" : {
          "x" : 378,
          "y" : 529
        }
      }, {
        "from" : {
          "x" : 378,
          "y" : 529
        },
        "to" : {
          "x" : 378,
          "y" : 538
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 374,
          "y" : 538
        },
        "b" : {
          "x" : 382,
          "y" : 538
        },
        "c" : {
          "x" : 378,
          "y" : 538
        },
        "type" : "STOP",
        "centre" : {
          "x" : 378,
          "y" : 538
        }
      }
    }, {
      "edgeId" : 88223,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  } ],
  "edges" : [ {
    "id" : 88225,
    "reactomeId" : 10988393,
    "displayName" : "CASP5 binds LPS micelles",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 147,
      "y" : 385
    },
    "minX" : 118,
    "maxX" : 179,
    "minY" : 379,
    "maxY" : 391,
    "reactionType" : "binding",
    "segments" : [ {
      "from" : {
        "x" : 118,
        "y" : 385
      },
      "to" : {
        "x" : 147,
        "y" : 385
      }
    }, {
      "from" : {
        "x" : 147,
        "y" : 385
      },
      "to" : {
        "x" : 179,
        "y" : 385
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 172,
        "y" : 389
      },
      "b" : {
        "x" : 179,
        "y" : 385
      },
      "c" : {
        "x" : 172,
        "y" : 381
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 172,
        "y" : 381
      }
    },
    "reactionShape" : {
      "c" : {
        "x" : 147,
        "y" : 385
      },
      "r" : 5,
      "type" : "CIRCLE",
      "centre" : {
        "x" : 147,
        "y" : 385
      }
    },
    "inputs" : [ {
      "id" : 88217,
      "points" : [ {
        "x" : 101,
        "y" : 403
      } ]
    }, {
      "id" : 88226,
      "points" : [ {
        "x" : 96,
        "y" : 368
      } ]
    } ],
    "outputs" : [ {
      "id" : 88227
    } ]
  }, {
    "id" : 88228,
    "reactomeId" : 10992859,
    "displayName" : "CASP5 dimerizes",
    "schemaClass" : "Polymerisation",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 293,
      "y" : 352
    },
    "minX" : 271,
    "maxX" : 320,
    "minY" : 346,
    "maxY" : 358,
    "reactionType" : "binding",
    "segments" : [ {
      "from" : {
        "x" : 271,
        "y" : 352
      },
      "to" : {
        "x" : 293,
        "y" : 352
      }
    }, {
      "from" : {
        "x" : 293,
        "y" : 352
      },
      "to" : {
        "x" : 320,
        "y" : 352
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 313,
        "y" : 356
      },
      "b" : {
        "x" : 320,
        "y" : 352
      },
      "c" : {
        "x" : 313,
        "y" : 348
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 313,
        "y" : 348
      }
    },
    "reactionShape" : {
      "c" : {
        "x" : 293,
        "y" : 352
      },
      "r" : 5,
      "type" : "CIRCLE",
      "centre" : {
        "x" : 293,
        "y" : 352
      }
    },
    "inputs" : [ {
      "id" : 88226,
      "points" : [ {
        "x" : 134,
        "y" : 352
      } ]
    }, {
      "id" : 88227,
      "points" : [ {
        "x" : 257,
        "y" : 365
      } ]
    } ],
    "outputs" : [ {
      "id" : 88229
    } ]
  }, {
    "id" : 88230,
    "reactomeId" : 10992857,
    "displayName" : "CASP5 autocatalysis on LPS micelles",
    "schemaClass" : "BlackBoxEvent",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 445,
      "y" : 351
    },
    "minX" : 414,
    "maxX" : 473,
    "minY" : 345,
    "maxY" : 357,
    "reactionType" : "omitted",
    "segments" : [ {
      "from" : {
        "x" : 414,
        "y" : 351
      },
      "to" : {
        "x" : 445,
        "y" : 351
      }
    }, {
      "from" : {
        "x" : 445,
        "y" : 351
      },
      "to" : {
        "x" : 473,
        "y" : 351
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 439,
        "y" : 345
      },
      "b" : {
        "x" : 451,
        "y" : 357
      },
      "s" : "\\\\",
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 445,
        "y" : 351
      }
    },
    "inputs" : [ {
      "id" : 88229
    } ],
    "outputs" : [ {
      "id" : 88231,
      "points" : [ {
        "x" : 504,
        "y" : 351
      } ]
    }, {
      "id" : 88217,
      "points" : [ {
        "x" : 135,
        "y" : 419
      }, {
        "x" : 475,
        "y" : 404
      } ]
    } ],
    "catalysts" : [ {
      "id" : 88229,
      "points" : [ {
        "x" : 414,
        "y" : 338
      }, {
        "x" : 444,
        "y" : 328
      } ]
    } ]
  }, {
    "id" : 88216,
    "reactomeId" : 10988387,
    "displayName" : "CASP4 binds LPS micelles",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 215,
      "y" : 507
    },
    "minX" : 199,
    "maxX" : 247,
    "minY" : 501,
    "maxY" : 513,
    "reactionType" : "binding",
    "segments" : [ {
      "from" : {
        "x" : 199,
        "y" : 507
      },
      "to" : {
        "x" : 215,
        "y" : 507
      }
    }, {
      "from" : {
        "x" : 215,
        "y" : 507
      },
      "to" : {
        "x" : 247,
        "y" : 508
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 240,
        "y" : 512
      },
      "b" : {
        "x" : 247,
        "y" : 508
      },
      "c" : {
        "x" : 240,
        "y" : 504
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 240,
        "y" : 504
      }
    },
    "reactionShape" : {
      "c" : {
        "x" : 215,
        "y" : 507
      },
      "r" : 5,
      "type" : "CIRCLE",
      "centre" : {
        "x" : 215,
        "y" : 507
      }
    },
    "inputs" : [ {
      "id" : 88217,
      "points" : [ {
        "x" : 108,
        "y" : 440
      } ]
    }, {
      "id" : 88218,
      "points" : [ {
        "x" : 121,
        "y" : 536
      } ]
    } ],
    "outputs" : [ {
      "id" : 88219
    } ]
  }, {
    "id" : 88220,
    "reactomeId" : 10988419,
    "displayName" : "CASP4 dimerizes",
    "schemaClass" : "Polymerisation",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 378,
      "y" : 547
    },
    "minX" : 355,
    "maxX" : 458,
    "minY" : 541,
    "maxY" : 553,
    "reactionType" : "binding",
    "segments" : [ {
      "from" : {
        "x" : 355,
        "y" : 547
      },
      "to" : {
        "x" : 378,
        "y" : 547
      }
    }, {
      "from" : {
        "x" : 378,
        "y" : 547
      },
      "to" : {
        "x" : 458,
        "y" : 548
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 451,
        "y" : 552
      },
      "b" : {
        "x" : 458,
        "y" : 548
      },
      "c" : {
        "x" : 451,
        "y" : 544
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 451,
        "y" : 544
      }
    },
    "reactionShape" : {
      "c" : {
        "x" : 378,
        "y" : 547
      },
      "r" : 5,
      "type" : "CIRCLE",
      "centre" : {
        "x" : 378,
        "y" : 547
      }
    },
    "inputs" : [ {
      "id" : 88219,
      "points" : [ {
        "x" : 323,
        "y" : 526
      } ]
    }, {
      "id" : 88218,
      "points" : [ {
        "x" : 141,
        "y" : 549
      } ]
    } ],
    "outputs" : [ {
      "id" : 88221
    } ],
    "inhibitors" : [ {
      "id" : 88222,
      "points" : [ {
        "x" : 408,
        "y" : 488
      }, {
        "x" : 378,
        "y" : 529
      } ]
    } ]
  }, {
    "id" : 88223,
    "reactomeId" : 10992861,
    "displayName" : "SERPINB1 binds CASP4",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 254,
      "y" : 473
    },
    "minX" : 209,
    "maxX" : 362,
    "minY" : 467,
    "maxY" : 479,
    "reactionType" : "binding",
    "segments" : [ {
      "from" : {
        "x" : 209,
        "y" : 473
      },
      "to" : {
        "x" : 254,
        "y" : 473
      }
    }, {
      "from" : {
        "x" : 254,
        "y" : 473
      },
      "to" : {
        "x" : 362,
        "y" : 473
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 355,
        "y" : 477
      },
      "b" : {
        "x" : 362,
        "y" : 473
      },
      "c" : {
        "x" : 355,
        "y" : 469
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 355,
        "y" : 469
      }
    },
    "reactionShape" : {
      "c" : {
        "x" : 254,
        "y" : 473
      },
      "r" : 5,
      "type" : "CIRCLE",
      "centre" : {
        "x" : 254,
        "y" : 473
      }
    },
    "inputs" : [ {
      "id" : 88224,
      "points" : [ {
        "x" : 199,
        "y" : 461
      } ]
    }, {
      "id" : 88218,
      "points" : [ {
        "x" : 110,
        "y" : 536
      } ]
    } ],
    "outputs" : [ {
      "id" : 88222
    } ]
  } ],
  "compartments" : [ {
    "id" : 88232,
    "reactomeId" : 70101,
    "displayName" : "cytosol",
    "schemaClass" : "Compartment",
    "renderableClass" : "Compartment",
    "position" : {
      "x" : 502,
      "y" : 474
    },
    "minX" : 0,
    "maxX" : 1004,
    "minY" : 0,
    "maxY" : 948,
    "prop" : {
      "x" : 0,
      "y" : 0,
      "width" : 1004,
      "height" : 948
    },
    "textPosition" : {
      "x" : 782,
      "y" : 13
    },
    "insets" : {
      "x" : 10,
      "y" : 10,
      "width" : 984,
      "height" : 928
    },
    "bgColor" : {
      "r" : 250,
      "g" : 240,
      "b" : 240
    },
    "componentIds" : [ 88216, 88219, 88217, 88218, 88220, 88221, 88222, 88223, 88224, 88227, 88225, 88226, 88228, 88229, 88230, 88231, 88233, 88234, 88235, 88236, 88237, 88238 ]
  } ],
  "notes" : [ ],
  "links" : [ ],
  "shadows" : [ {
    "id" : 88235,
    "reactomeId" : 10996013,
    "displayName" : "CASP5 inflammasome assembly",
    "schemaClass" : "Pathway",
    "renderableClass" : "Shadow",
    "position" : {
      "x" : 323,
      "y" : 385
    },
    "minX" : 28,
    "maxX" : 619,
    "minY" : 324,
    "maxY" : 447,
    "prop" : {
      "x" : 28,
      "y" : 324,
      "width" : 591,
      "height" : 72
    },
    "points" : [ {
      "x" : 28,
      "y" : 324
    }, {
      "x" : 619,
      "y" : 324
    }, {
      "x" : 619,
      "y" : 447
    }, {
      "x" : 28,
      "y" : 447
    } ],
    "colour" : "#dc3912"
  }, {
    "id" : 88234,
    "reactomeId" : 10996009,
    "displayName" : "CASP4 inflammasome assembly",
    "schemaClass" : "Pathway",
    "renderableClass" : "Shadow",
    "position" : {
      "x" : 297,
      "y" : 487
    },
    "minX" : 36,
    "maxX" : 559,
    "minY" : 396,
    "maxY" : 578,
    "prop" : {
      "x" : 36,
      "y" : 447,
      "width" : 523,
      "height" : 131
    },
    "points" : [ {
      "x" : 36,
      "y" : 396
    }, {
      "x" : 559,
      "y" : 396
    }, {
      "x" : 559,
      "y" : 578
    }, {
      "x" : 36,
      "y" : 578
    } ],
    "colour" : "#4684ee"
  } ],
  "minX" : 0,
  "maxX" : 1004,
  "minY" : 0,
  "maxY" : 948,
  "disease" : false
}