{
  "dbId" : 10993777,
  "stId" : "R-CEL-109704",
  "speciesName" : "Caenorhabditis elegans",
  "nodes" : [ {
    "dbId" : 76577,
    "stId" : "R-ALL-76577",
    "displayName" : "AMP [cytosol]",
    "schemaClass" : "SimpleEntity",
    "speciesId" : 0,
    "diagramIds" : [ 91912 ],
    "identifier" : "456215",
    "standardIdentifier" : "chebi:456215",
    "referenceType" : "ReferenceMolecule",
    "parents" : [ ],
    "children" : [ ]
  }, {
    "dbId" : 10920867,
    "stId" : "R-CEL-162387",
    "displayName" : "p-T309,S474-AKT2:PIP3 [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 68320,
    "diagramIds" : [ 91906 ],
    "parents" : [ ],
    "children" : [ 179838, 10920865 ]
  }, {
    "dbId" : 10920865,
    "stId" : "R-CEL-202062",
    "displayName" : "phospho-p-T309,S474-AKT2 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 68320,
    "identifier" : "Q17941",
    "standardIdentifier" : "uniprot:Q17941",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 10920867 ],
    "children" : [ ]
  }, {
    "dbId" : 10920846,
    "stId" : "R-CEL-49859",
    "displayName" : "AKT2 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 68320,
    "identifier" : "Q17941",
    "standardIdentifier" : "uniprot:Q17941",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 10920848, 10920850 ],
    "children" : [ ]
  }, {
    "dbId" : 29356,
    "stId" : "R-ALL-29356",
    "displayName" : "H2O [cytosol]",
    "schemaClass" : "SimpleEntity",
    "speciesId" : 0,
    "diagramIds" : [ 91910 ],
    "identifier" : "15377",
    "standardIdentifier" : "chebi:15377",
    "referenceType" : "ReferenceMolecule",
    "parents" : [ ],
    "children" : [ ]
  }, {
    "dbId" : 10994825,
    "stId" : "R-CEL-449836",
    "displayName" : "Other interleukin signaling",
    "schemaClass" : "Pathway",
    "speciesId" : 68320,
    "diagramIds" : [ 91921 ]
  }, {
    "dbId" : 10920841,
    "stId" : "R-CEL-162411",
    "displayName" : "TRIB3 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 68320,
    "diagramIds" : [ 91903 ],
    "identifier" : "G5EED4",
    "standardIdentifier" : "uniprot:G5EED4",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 10920848 ],
    "children" : [ ]
  }, {
    "dbId" : 10922742,
    "stId" : "R-CEL-162419",
    "displayName" : "phospho-p-S295-PDE3B [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 68320,
    "diagramIds" : [ 91913 ],
    "identifier" : "Q8I0P7",
    "standardIdentifier" : "uniprot:Q8I0P7",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ ],
    "children" : [ ]
  }, {
    "dbId" : 10920850,
    "stId" : "R-CEL-109696",
    "displayName" : "AKT2:PIP3 [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 68320,
    "diagramIds" : [ 91902 ],
    "parents" : [ ],
    "children" : [ 179838, 10920846 ]
  }, {
    "dbId" : 30389,
    "stId" : "R-ALL-30389",
    "displayName" : "cAMP [cytosol]",
    "schemaClass" : "SimpleEntity",
    "speciesId" : 0,
    "diagramIds" : [ 91911 ],
    "identifier" : "58165",
    "standardIdentifier" : "chebi:58165",
    "referenceType" : "ReferenceMolecule",
    "parents" : [ ],
    "children" : [ ]
  }, {
    "dbId" : 10920848,
    "stId" : "R-CEL-162401",
    "displayName" : "AKT2:THEM4,TRIB3 [cytosol]",
    "schemaClass" : "Complex",
    "speciesId" : 68320,
    "diagramIds" : [ 91901 ],
    "parents" : [ ],
    "children" : [ 10920841, 10920846 ]
  }, {
    "dbId" : 113592,
    "stId" : "R-ALL-113592",
    "displayName" : "ATP [cytosol]",
    "schemaClass" : "SimpleEntity",
    "speciesId" : 0,
    "diagramIds" : [ 91905 ],
    "identifier" : "30616",
    "standardIdentifier" : "chebi:30616",
    "referenceType" : "ReferenceMolecule",
    "parents" : [ ],
    "children" : [ ]
  }, {
    "dbId" : 29370,
    "stId" : "R-ALL-29370",
    "displayName" : "ADP [cytosol]",
    "schemaClass" : "SimpleEntity",
    "speciesId" : 0,
    "diagramIds" : [ 91907 ],
    "identifier" : "456216",
    "standardIdentifier" : "chebi:456216",
    "referenceType" : "ReferenceMolecule",
    "parents" : [ ],
    "children" : [ ]
  }, {
    "dbId" : 179838,
    "stId" : "R-ALL-179838",
    "displayName" : "PI(3,4,5)P3 [plasma membrane]",
    "schemaClass" : "SimpleEntity",
    "speciesId" : 0,
    "diagramIds" : [ 91897 ],
    "identifier" : "57836",
    "standardIdentifier" : "chebi:57836",
    "referenceType" : "ReferenceMolecule",
    "parents" : [ 10920850, 10920867, 10920859 ],
    "children" : [ ]
  }, {
    "dbId" : 10920859,
    "stId" : "R-CEL-109697",
    "displayName" : "PDPK1:PIP3 [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 68320,
    "diagramIds" : [ 91908, 91899 ],
    "parents" : [ ],
    "children" : [ 10920857, 179838 ]
  }, {
    "dbId" : 10920857,
    "stId" : "R-CEL-61459",
    "displayName" : "PDPK1 [plasma membrane]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 68320,
    "diagramIds" : [ 91898 ],
    "identifier" : "Q9UA62",
    "standardIdentifier" : "uniprot:Q9UA62",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 10920859 ],
    "children" : [ ]
  } ],
  "edges" : [ {
    "dbId" : 10920870,
    "stId" : "R-CEL-109702",
    "displayName" : "PDPK1 phosphorylates AKT2",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "preceding" : [ 10920861, 10920852 ],
    "inputs" : [ 113592, 10920850 ],
    "outputs" : [ 29370, 10920867 ],
    "catalysts" : [ 10920859 ],
    "efs" : [ ],
    "diagramIds" : [ 91904 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10920852,
    "stId" : "R-CEL-109700",
    "displayName" : "AKT2 binds PIP3",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "following" : [ 10920870 ],
    "inputs" : [ 179838, 10920848 ],
    "outputs" : [ 10920841, 10920850 ],
    "efs" : [ ],
    "diagramIds" : [ 91900 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10920861,
    "stId" : "R-CEL-109701",
    "displayName" : "PDPK1 binds PIP3",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "following" : [ 10920870 ],
    "inputs" : [ 10920857, 179838 ],
    "outputs" : [ 10920859 ],
    "efs" : [ ],
    "diagramIds" : [ 91896 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10922745,
    "stId" : "R-CEL-162425",
    "displayName" : "p-S295-PDE3B hydrolyses cAMP to AMP",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "inputs" : [ 29356, 30389 ],
    "outputs" : [ 76577 ],
    "catalysts" : [ 10922742 ],
    "efs" : [ ],
    "diagramIds" : [ 91909 ],
    "entityFunctionalStatus" : [ ]
  } ],
  "subpathways" : [ {
    "dbId" : 10994025,
    "stId" : "R-CEL-165160",
    "displayName" : "PDE3B signalling",
    "events" : [ 10922745 ]
  }, {
    "dbId" : 10994027,
    "stId" : "R-CEL-109703",
    "displayName" : "PKB-mediated events",
    "events" : [ 10922745 ]
  }, {
    "dbId" : 10993775,
    "stId" : "R-CEL-165158",
    "displayName" : "Activation of AKT2",
    "events" : [ 10920870, 10920852, 10920861 ]
  } ]
}