{
  "dbId" : 10911448,
  "stId" : "R-DME-194138",
  "speciesName" : "Drosophila melanogaster",
  "nodes" : [ {
    "dbId" : 10841253,
    "stId" : "R-DME-171009-2",
    "displayName" : "phospho-p-T180,Y182-MAPK11 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 56210,
    "identifier" : "O62618",
    "standardIdentifier" : "uniprot:O62618",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 10841257 ],
    "children" : [ ]
  }, {
    "dbId" : 10837156,
    "stId" : "R-DME-194510",
    "displayName" : "RHOA [plasma membrane]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 56210,
    "identifier" : "P48148",
    "standardIdentifier" : "uniprot:P48148",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Rho1", "CG8416" ],
    "parents" : [ 10837160 ],
    "children" : [ ]
  }, {
    "dbId" : 10839204,
    "stId" : "R-DME-165676",
    "displayName" : "Lst8 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 56210,
    "identifier" : "Q9W328",
    "standardIdentifier" : "uniprot:Q9W328",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Lst8" ],
    "parents" : [ 10842968 ],
    "children" : [ ]
  }, {
    "dbId" : 10841255,
    "stId" : "R-DME-171009-3",
    "displayName" : "phospho-p-T180,Y182-MAPK11 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 56210,
    "identifier" : "P83100",
    "standardIdentifier" : "uniprot:P83100",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 10841257 ],
    "children" : [ ]
  }, {
    "dbId" : 10868902,
    "stId" : "R-DME-5694031",
    "displayName" : "Hem [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 56210,
    "identifier" : "P55162",
    "standardIdentifier" : "uniprot:P55162",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Hem" ],
    "parents" : [ 10868904 ],
    "children" : [ ]
  }, {
    "dbId" : 10841249,
    "stId" : "R-DME-187726",
    "displayName" : "p-S272,T222,T334-MAPKAPK2, p-S,2T-MAPKAPK3 [cytosol]",
    "schemaClass" : "DefinedSet",
    "speciesId" : 56210,
    "diagramIds" : [ 34560 ],
    "parents" : [ ],
    "children" : [ 10841243, 10841247 ]
  }, {
    "dbId" : 10841251,
    "stId" : "R-DME-171009",
    "displayName" : "phospho-p-T180,Y182-MAPK11 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 56210,
    "identifier" : "O61443",
    "standardIdentifier" : "uniprot:O61443",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 10841257 ],
    "children" : [ ]
  }, {
    "dbId" : 10868898,
    "stId" : "R-DME-5672575",
    "displayName" : "Cyfip [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 56210,
    "identifier" : "Q9VF87",
    "standardIdentifier" : "uniprot:Q9VF87",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Cyfip" ],
    "parents" : [ 10868904 ],
    "children" : [ ]
  }, {
    "dbId" : 10841261,
    "stId" : "R-DME-170997",
    "displayName" : "p-p38 MAPK alpha/beta [cytosol]",
    "schemaClass" : "DefinedSet",
    "speciesId" : 56210,
    "parents" : [ 10841263 ],
    "children" : [ 10841259, 10841257 ]
  }, {
    "dbId" : 10841263,
    "stId" : "R-DME-170993",
    "displayName" : "Phospho-MAP kinase p38 (Mg2+ cofactor) [cytosol]",
    "schemaClass" : "Complex",
    "speciesId" : 56210,
    "diagramIds" : [ 34591 ],
    "parents" : [ ],
    "children" : [ 10841261, 29926 ]
  }, {
    "dbId" : 10839209,
    "stId" : "R-DME-165662",
    "displayName" : "mTor [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 56210,
    "identifier" : "Q9VK45",
    "standardIdentifier" : "uniprot:Q9VK45",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "mTor" ],
    "parents" : [ 10842968 ],
    "children" : [ ]
  }, {
    "dbId" : 10841257,
    "stId" : "R-DME-171009-4",
    "displayName" : "Homologues of p-T180,Y182-MAPK11 [cytosol]",
    "schemaClass" : "DefinedSet",
    "speciesId" : 56210,
    "parents" : [ 10841261 ],
    "children" : [ 10841251, 10841255, 10841253 ]
  }, {
    "dbId" : 10837160,
    "stId" : "R-DME-5665993",
    "displayName" : "RHOA:GTP [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 56210,
    "diagramIds" : [ 34484 ],
    "parents" : [ 10850527 ],
    "children" : [ 29438, 10837156 ]
  }, {
    "dbId" : 10868904,
    "stId" : "R-DME-2029154",
    "displayName" : "WAVE Regulatory Complex [cytosol]",
    "schemaClass" : "Complex",
    "speciesId" : 56210,
    "diagramIds" : [ 34491 ],
    "parents" : [ 10868906 ],
    "children" : [ 10868859, 10868893, 10868898, 10868864, 10868902, 10868869 ]
  }, {
    "dbId" : 10841259,
    "stId" : "R-DME-428935",
    "displayName" : "phospho-p-T180,Y182-MAPK14 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 56210,
    "identifier" : "O61443",
    "standardIdentifier" : "uniprot:O61443",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 10841261 ],
    "children" : [ ]
  }, {
    "dbId" : 10868906,
    "stId" : "R-DME-2029147",
    "displayName" : "WRC:IRSp53/58:RAC1:GTP:PIP3 [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 56210,
    "diagramIds" : [ 34494 ],
    "parents" : [ ],
    "children" : [ 351067, 10868904, 179838, 10868854 ]
  }, {
    "dbId" : 71185,
    "stId" : "R-ALL-71185",
    "displayName" : "ferroheme [cytosol]",
    "schemaClass" : "SimpleEntity",
    "speciesId" : 0,
    "identifier" : "60344",
    "standardIdentifier" : "chebi:60344",
    "referenceType" : "ReferenceMolecule",
    "parents" : [ 10843923, 10843887 ],
    "children" : [ ]
  }, {
    "dbId" : 10850486,
    "stId" : "R-DME-191735-2",
    "displayName" : "alpha-Cat [plasma membrane]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 56210,
    "identifier" : "P35220",
    "standardIdentifier" : "uniprot:P35220",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "alpha-Cat" ],
    "parents" : [ 10850493 ],
    "children" : [ ]
  }, {
    "dbId" : 10850481,
    "stId" : "R-DME-191735",
    "displayName" : "Sry-alpha [plasma membrane]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 56210,
    "identifier" : "P07666",
    "standardIdentifier" : "uniprot:P07666",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Sry-alpha" ],
    "parents" : [ 10850493 ],
    "children" : [ ]
  }, {
    "dbId" : 10837181,
    "stId" : "R-DME-58198",
    "displayName" : "PRKCB [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 56210,
    "identifier" : "P05130",
    "standardIdentifier" : "uniprot:P05130",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 10837185 ],
    "children" : [ ]
  }, {
    "dbId" : 10850493,
    "stId" : "R-DME-191735-4",
    "displayName" : "Homologues of CTNNA1 [plasma membrane]",
    "schemaClass" : "DefinedSet",
    "speciesId" : 56210,
    "parents" : [ 10877225, 10877221 ],
    "children" : [ 10850491, 10850481, 10850486 ]
  }, {
    "dbId" : 10837183,
    "stId" : "R-DME-58198-2",
    "displayName" : "PRKCB [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 56210,
    "identifier" : "P13677",
    "standardIdentifier" : "uniprot:P13677",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 10837185 ],
    "children" : [ ]
  }, {
    "dbId" : 10850491,
    "stId" : "R-DME-191735-3",
    "displayName" : "Spt [plasma membrane]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 56210,
    "identifier" : "Q8SYP8",
    "standardIdentifier" : "uniprot:Q8SYP8",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Spt" ],
    "parents" : [ 10850493 ],
    "children" : [ ]
  }, {
    "dbId" : 10868869,
    "stId" : "R-DME-1671643",
    "displayName" : "Abi [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 56210,
    "identifier" : "A0A0B4K774",
    "standardIdentifier" : "uniprot:A0A0B4K774",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Abi" ],
    "parents" : [ 10868904 ],
    "children" : [ ]
  }, {
    "dbId" : 10876548,
    "stId" : "R-DME-5218689",
    "displayName" : "HSBP1 oligomer [cytosol]",
    "schemaClass" : "Polymer",
    "speciesId" : 56210,
    "parents" : [ 10876550 ],
    "children" : [ 10854675 ]
  }, {
    "dbId" : 10876550,
    "stId" : "R-DME-5218769",
    "displayName" : "HSP27 oligomer:F-actin [cytosol]",
    "schemaClass" : "Complex",
    "speciesId" : 56210,
    "diagramIds" : [ 34556 ],
    "parents" : [ ],
    "children" : [ 10849939, 10876548 ]
  }, {
    "dbId" : 10868864,
    "stId" : "R-DME-1671645",
    "displayName" : "HSPC300 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 56210,
    "identifier" : "Q8MLQ0",
    "standardIdentifier" : "uniprot:Q8MLQ0",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "HSPC300" ],
    "parents" : [ 10868904 ],
    "children" : [ ]
  }, {
    "dbId" : 10868876,
    "stId" : "R-DME-200972",
    "displayName" : "SCAR [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 56210,
    "identifier" : "F2FB81",
    "standardIdentifier" : "uniprot:F2FB81",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "SCAR" ],
    "parents" : [ 10868883 ],
    "children" : [ ]
  }, {
    "dbId" : 10836623,
    "stId" : "R-DME-58196",
    "displayName" : "PRKCA [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 56210,
    "identifier" : "P05130",
    "standardIdentifier" : "uniprot:P05130",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 10836630 ],
    "children" : [ ]
  }, {
    "dbId" : 10876555,
    "stId" : "R-DME-5218697",
    "displayName" : "phospho-p-S15,S78,S82-HSP27 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 56210,
    "diagramIds" : [ 34558 ],
    "identifier" : "Q8IQW5",
    "standardIdentifier" : "uniprot:Q8IQW5",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ ],
    "children" : [ ]
  }, {
    "dbId" : 10868885,
    "stId" : "R-DME-200965",
    "displayName" : "SCAR [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 56210,
    "identifier" : "F2FB81",
    "standardIdentifier" : "uniprot:F2FB81",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "SCAR" ],
    "parents" : [ 10868889 ],
    "children" : [ ]
  }, {
    "dbId" : 10836628,
    "stId" : "R-DME-58196-2",
    "displayName" : "PRKCA [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 56210,
    "identifier" : "P13677",
    "standardIdentifier" : "uniprot:P13677",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 10836630 ],
    "children" : [ ]
  }, {
    "dbId" : 10841236,
    "stId" : "R-DME-187764",
    "displayName" : "MAPKAPK3 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 56210,
    "identifier" : "P49071",
    "standardIdentifier" : "uniprot:P49071",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 10841238 ],
    "children" : [ ]
  }, {
    "dbId" : 10868887,
    "stId" : "R-DME-200965-2",
    "displayName" : "gukh [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 56210,
    "identifier" : "Q9VE13",
    "standardIdentifier" : "uniprot:Q9VE13",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "gukh" ],
    "parents" : [ 10868889 ],
    "children" : [ ]
  }, {
    "dbId" : 10836630,
    "stId" : "R-DME-58196-3",
    "displayName" : "Homologues of PRKCA [cytosol]",
    "schemaClass" : "DefinedSet",
    "speciesId" : 56210,
    "parents" : [ 10876521 ],
    "children" : [ 10836623, 10836628 ]
  }, {
    "dbId" : 10841238,
    "stId" : "R-DME-187699",
    "displayName" : "MAPKAP kinase [cytosol]",
    "schemaClass" : "DefinedSet",
    "speciesId" : 56210,
    "diagramIds" : [ 34588 ],
    "parents" : [ ],
    "children" : [ 10841234, 10841236 ]
  }, {
    "dbId" : 10868881,
    "stId" : "R-DME-200972-2",
    "displayName" : "gukh [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 56210,
    "identifier" : "Q9VE13",
    "standardIdentifier" : "uniprot:Q9VE13",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "gukh" ],
    "parents" : [ 10868883 ],
    "children" : [ ]
  }, {
    "dbId" : 10868883,
    "stId" : "R-DME-200972-3",
    "displayName" : "Homologues of WASF2 [cytosol]",
    "schemaClass" : "DefinedSet",
    "speciesId" : 56210,
    "parents" : [ 10868893 ],
    "children" : [ 10868876, 10868881 ]
  }, {
    "dbId" : 10849939,
    "stId" : "R-DME-201877",
    "displayName" : "F-actin [cytosol]",
    "schemaClass" : "Polymer",
    "speciesId" : 56210,
    "diagramIds" : [ 34557 ],
    "parents" : [ 10876550 ],
    "children" : [ 10844131 ]
  }, {
    "dbId" : 10841234,
    "stId" : "R-DME-187743",
    "displayName" : "MAPKAPK2 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 56210,
    "identifier" : "P49071",
    "standardIdentifier" : "uniprot:P49071",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 10841238 ],
    "children" : [ ]
  }, {
    "dbId" : 10868893,
    "stId" : "R-DME-2029114",
    "displayName" : "WAVEs [cytosol]",
    "schemaClass" : "CandidateSet",
    "speciesId" : 56210,
    "parents" : [ 10868904 ],
    "children" : [ 10868883, 10868891, 10868889 ]
  }, {
    "dbId" : 10841247,
    "stId" : "R-DME-187723",
    "displayName" : "phospho-p-S,2T-MAPKAPK3 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 56210,
    "identifier" : "P49071",
    "standardIdentifier" : "uniprot:P49071",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 10841249 ],
    "children" : [ ]
  }, {
    "dbId" : 10868889,
    "stId" : "R-DME-200965-3",
    "displayName" : "Homologues of WASF1 [cytosol]",
    "schemaClass" : "DefinedSet",
    "speciesId" : 56210,
    "parents" : [ 10868893 ],
    "children" : [ 10868887, 10868885 ]
  }, {
    "dbId" : 10836635,
    "stId" : "R-DME-58200",
    "displayName" : "PRKCD [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 56210,
    "identifier" : "P83099",
    "standardIdentifier" : "uniprot:P83099",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 10876521 ],
    "children" : [ ]
  }, {
    "dbId" : 10841243,
    "stId" : "R-DME-187760",
    "displayName" : "phospho-p-S272,T222,T334-MAPKAPK2 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 56210,
    "identifier" : "P49071",
    "standardIdentifier" : "uniprot:P49071",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 10841249 ],
    "children" : [ ]
  }, {
    "dbId" : 10868891,
    "stId" : "R-DME-200975",
    "displayName" : "SCAR [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 56210,
    "identifier" : "F2FB81",
    "standardIdentifier" : "uniprot:F2FB81",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "SCAR" ],
    "parents" : [ 10868893 ],
    "children" : [ ]
  }, {
    "dbId" : 10876641,
    "stId" : "R-DME-5228987",
    "displayName" : "RHOA:GTP:Mg2+:Activated ROCK1,ROCK2 [cytosol]",
    "schemaClass" : "Complex",
    "speciesId" : 56210,
    "diagramIds" : [ 34488 ],
    "parents" : [ ],
    "children" : [ 10850525, 10874565 ]
  }, {
    "dbId" : 10843885,
    "stId" : "R-DME-534993",
    "displayName" : "2xPalmC-MyrG-NOS3 [plasma membrane]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 56210,
    "identifier" : "Q27571",
    "standardIdentifier" : "uniprot:Q27571",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 10843887 ],
    "children" : [ ]
  }, {
    "dbId" : 10843887,
    "stId" : "R-DME-203639",
    "displayName" : "palmitoylated, myristoylated eNOS dimer [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 56210,
    "parents" : [ 10843912 ],
    "children" : [ 29386, 10843885, 73524, 29426, 71185 ]
  }, {
    "dbId" : 10843893,
    "stId" : "R-DME-9016884-3",
    "displayName" : "CALM1 [plasma membrane]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 56210,
    "identifier" : "P47949",
    "standardIdentifier" : "uniprot:P47949",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 10843903 ],
    "children" : [ ]
  }, {
    "dbId" : 10843895,
    "stId" : "R-DME-9016884-4",
    "displayName" : "azot [plasma membrane]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 56210,
    "identifier" : "Q7K049",
    "standardIdentifier" : "uniprot:Q7K049",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "azot" ],
    "parents" : [ 10843903 ],
    "children" : [ ]
  }, {
    "dbId" : 10843889,
    "stId" : "R-DME-9016884",
    "displayName" : "CALM1 [plasma membrane]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 56210,
    "identifier" : "P47947",
    "standardIdentifier" : "uniprot:P47947",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 10843903 ],
    "children" : [ ]
  }, {
    "dbId" : 10843891,
    "stId" : "R-DME-9016884-2",
    "displayName" : "CALM1 [plasma membrane]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 56210,
    "identifier" : "P47948",
    "standardIdentifier" : "uniprot:P47948",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 10843903 ],
    "children" : [ ]
  }, {
    "dbId" : 10843901,
    "stId" : "R-DME-9016884-7",
    "displayName" : "TpnC25D [plasma membrane]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 56210,
    "identifier" : "Q9VMT2",
    "standardIdentifier" : "uniprot:Q9VMT2",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "TpnC25D" ],
    "parents" : [ 10843903 ],
    "children" : [ ]
  }, {
    "dbId" : 10843903,
    "stId" : "R-DME-9016884-8",
    "displayName" : "Homologues of CALM1 [plasma membrane]",
    "schemaClass" : "DefinedSet",
    "speciesId" : 56210,
    "parents" : [ 10843905 ],
    "children" : [ 10843899, 10843897, 10843901, 10843891, 10843889, 10843895, 10843893 ]
  }, {
    "dbId" : 10843897,
    "stId" : "R-DME-9016884-5",
    "displayName" : "TpnC4 [plasma membrane]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 56210,
    "identifier" : "Q7K860",
    "standardIdentifier" : "uniprot:Q7K860",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "TpnC4" ],
    "parents" : [ 10843903 ],
    "children" : [ ]
  }, {
    "dbId" : 10843899,
    "stId" : "R-DME-9016884-6",
    "displayName" : "CG10022 [plasma membrane]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 56210,
    "identifier" : "Q8IQ15",
    "standardIdentifier" : "uniprot:Q8IQ15",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "CG10022" ],
    "parents" : [ 10843903 ],
    "children" : [ ]
  }, {
    "dbId" : 10874565,
    "stId" : "R-DME-3858473",
    "displayName" : "RHOA:GTP:Mg2+ [cytosol]",
    "schemaClass" : "Complex",
    "speciesId" : 56210,
    "parents" : [ 10876641 ],
    "children" : [ 29438, 10853209, 29926 ]
  }, {
    "dbId" : 10837185,
    "stId" : "R-DME-58198-3",
    "displayName" : "Homologues of PRKCB [cytosol]",
    "schemaClass" : "DefinedSet",
    "speciesId" : 56210,
    "parents" : [ 10876521 ],
    "children" : [ 10837183, 10837181 ]
  }, {
    "dbId" : 10850519,
    "stId" : "R-DME-419058",
    "displayName" : "Prm [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 56210,
    "identifier" : "P35415",
    "standardIdentifier" : "uniprot:P35415",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Prm" ],
    "parents" : [ 10850523 ],
    "children" : [ ]
  }, {
    "dbId" : 10850525,
    "stId" : "R-DME-419057",
    "displayName" : "ROCK1,ROCK2 [cytosol]",
    "schemaClass" : "DefinedSet",
    "speciesId" : 56210,
    "diagramIds" : [ 34485 ],
    "parents" : [ 10850527, 10876641 ],
    "children" : [ 10850523, 10843694 ]
  }, {
    "dbId" : 10850527,
    "stId" : "R-DME-422483",
    "displayName" : "Activated ROCK:RhoA/B/C:GTP [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 56210,
    "diagramIds" : [ 34486 ],
    "parents" : [ ],
    "children" : [ 10837160, 10850525 ]
  }, {
    "dbId" : 179838,
    "stId" : "R-ALL-179838",
    "displayName" : "PI(3,4,5)P3 [plasma membrane]",
    "schemaClass" : "SimpleEntity",
    "speciesId" : 0,
    "diagramIds" : [ 34499, 34492 ],
    "identifier" : "57836",
    "standardIdentifier" : "chebi:57836",
    "referenceType" : "ReferenceMolecule",
    "parents" : [ 10876517, 10868906, 10842942, 10842952, 10835903, 10842966 ],
    "children" : [ ]
  }, {
    "dbId" : 10850521,
    "stId" : "R-DME-419058-2",
    "displayName" : "ROCK2 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 56210,
    "identifier" : "Q9VXE3",
    "standardIdentifier" : "uniprot:Q9VXE3",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 10850523 ],
    "children" : [ ]
  }, {
    "dbId" : 10850523,
    "stId" : "R-DME-419058-3",
    "displayName" : "Homologues of ROCK2 [cytosol]",
    "schemaClass" : "DefinedSet",
    "speciesId" : 56210,
    "parents" : [ 10850525 ],
    "children" : [ 10850521, 10850519 ]
  }, {
    "dbId" : 10876452,
    "stId" : "R-DME-5218728-2",
    "displayName" : "phospho-p-T500-PRKCB [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 56210,
    "identifier" : "P13677",
    "standardIdentifier" : "uniprot:P13677",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 10876454 ],
    "children" : [ ]
  }, {
    "dbId" : 10876454,
    "stId" : "R-DME-5218728-3",
    "displayName" : "Homologues of p-T500-PRKCB [cytosol]",
    "schemaClass" : "DefinedSet",
    "speciesId" : 56210,
    "parents" : [ 10876458 ],
    "children" : [ 10876449, 10876452 ]
  }, {
    "dbId" : 10876449,
    "stId" : "R-DME-5218728",
    "displayName" : "phospho-p-T500-PRKCB [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 56210,
    "identifier" : "P05130",
    "standardIdentifier" : "uniprot:P05130",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 10876454 ],
    "children" : [ ]
  }, {
    "dbId" : 10876461,
    "stId" : "R-DME-5218698",
    "displayName" : "phospho-p-T410,T563-PRKCZ [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 56210,
    "identifier" : "A1Z9X0",
    "standardIdentifier" : "uniprot:A1Z9X0",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 10876485 ],
    "children" : [ ]
  }, {
    "dbId" : 10843694,
    "stId" : "R-DME-212509",
    "displayName" : "ROCK1 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 56210,
    "identifier" : "Q9VXE3",
    "standardIdentifier" : "uniprot:Q9VXE3",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 10850525 ],
    "children" : [ ]
  }, {
    "dbId" : 10876456,
    "stId" : "R-DME-5218746",
    "displayName" : "phospho-p-T507-PRKCD [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 56210,
    "identifier" : "P83099",
    "standardIdentifier" : "uniprot:P83099",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 10876458 ],
    "children" : [ ]
  }, {
    "dbId" : 10876458,
    "stId" : "R-DME-5218754",
    "displayName" : "p-PKCA,p-PKCB,p-PKCZ,p-PKCD [cytosol]",
    "schemaClass" : "DefinedSet",
    "speciesId" : 56210,
    "diagramIds" : [ 34564 ],
    "parents" : [ ],
    "children" : [ 10876456, 10876446, 10876454, 10876438 ]
  }, {
    "dbId" : 10876469,
    "stId" : "R-DME-5218706-2",
    "displayName" : "phospho-p-T500,T642,S661-PRKCB [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 56210,
    "identifier" : "P13677",
    "standardIdentifier" : "uniprot:P13677",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 10876471 ],
    "children" : [ ]
  }, {
    "dbId" : 10876471,
    "stId" : "R-DME-5218706-3",
    "displayName" : "Homologues of p-T500,T642,S661-PRKCB [cytosol]",
    "schemaClass" : "DefinedSet",
    "speciesId" : 56210,
    "parents" : [ 10876485 ],
    "children" : [ 10876465, 10876469 ]
  }, {
    "dbId" : 112275,
    "stId" : "R-ALL-112275",
    "displayName" : "DAGs [plasma membrane]",
    "schemaClass" : "SimpleEntity",
    "speciesId" : 0,
    "diagramIds" : [ 34572 ],
    "identifier" : "18035",
    "standardIdentifier" : "chebi:18035",
    "referenceType" : "ReferenceMolecule",
    "parents" : [ 10876492 ],
    "children" : [ ]
  }, {
    "dbId" : 179856,
    "stId" : "R-ALL-179856",
    "displayName" : "PI(4,5)P2 [plasma membrane]",
    "schemaClass" : "SimpleEntity",
    "speciesId" : 0,
    "diagramIds" : [ 34497 ],
    "identifier" : "58456",
    "standardIdentifier" : "chebi:58456",
    "referenceType" : "ReferenceMolecule",
    "parents" : [ ],
    "children" : [ ]
  }, {
    "dbId" : 10876465,
    "stId" : "R-DME-5218706",
    "displayName" : "phospho-p-T500,T642,S661-PRKCB [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 56210,
    "identifier" : "P05130",
    "standardIdentifier" : "uniprot:P05130",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 10876471 ],
    "children" : [ ]
  }, {
    "dbId" : 10876477,
    "stId" : "R-DME-4332337",
    "displayName" : "phospho-p-T497,T638,S657-PRKCA [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 56210,
    "identifier" : "P05130",
    "standardIdentifier" : "uniprot:P05130",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 10876483 ],
    "children" : [ ]
  }, {
    "dbId" : 10876473,
    "stId" : "R-DME-5218734",
    "displayName" : "phospho-p-T507,S645,S664-PRKCD [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 56210,
    "identifier" : "P83099",
    "standardIdentifier" : "uniprot:P83099",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 10876485 ],
    "children" : [ ]
  }, {
    "dbId" : 29356,
    "stId" : "R-ALL-29356",
    "displayName" : "H2O [cytosol]",
    "schemaClass" : "SimpleEntity",
    "speciesId" : 0,
    "diagramIds" : [ 34552 ],
    "identifier" : "15377",
    "standardIdentifier" : "chebi:15377",
    "referenceType" : "ReferenceMolecule",
    "parents" : [ ],
    "children" : [ ]
  }, {
    "dbId" : 29870,
    "stId" : "R-ALL-29870",
    "displayName" : "BH4 [cytosol]",
    "schemaClass" : "SimpleEntity",
    "speciesId" : 0,
    "diagramIds" : [ 34542 ],
    "identifier" : "59560",
    "standardIdentifier" : "chebi:59560",
    "referenceType" : "ReferenceMolecule",
    "parents" : [ 10843930, 10843923 ],
    "children" : [ ]
  }, {
    "dbId" : 10876438,
    "stId" : "R-DME-437181",
    "displayName" : "phospho-p-T410-PRKCZ [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 56210,
    "identifier" : "A1Z9X0",
    "standardIdentifier" : "uniprot:A1Z9X0",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 10876458 ],
    "children" : [ ]
  }, {
    "dbId" : 29364,
    "stId" : "R-ALL-29364",
    "displayName" : "NADPH [cytosol]",
    "schemaClass" : "SimpleEntity",
    "speciesId" : 0,
    "diagramIds" : [ 34545 ],
    "identifier" : "57783",
    "standardIdentifier" : "chebi:57783",
    "referenceType" : "ReferenceMolecule",
    "parents" : [ ],
    "children" : [ ]
  }, {
    "dbId" : 29366,
    "stId" : "R-ALL-29366",
    "displayName" : "NADP+ [cytosol]",
    "schemaClass" : "SimpleEntity",
    "speciesId" : 0,
    "diagramIds" : [ 34550 ],
    "identifier" : "58349",
    "standardIdentifier" : "chebi:58349",
    "referenceType" : "ReferenceMolecule",
    "parents" : [ ],
    "children" : [ ]
  }, {
    "dbId" : 29368,
    "stId" : "R-ALL-29368",
    "displayName" : "O2 [cytosol]",
    "schemaClass" : "SimpleEntity",
    "speciesId" : 0,
    "diagramIds" : [ 34547 ],
    "identifier" : "15379",
    "standardIdentifier" : "chebi:15379",
    "referenceType" : "ReferenceMolecule",
    "parents" : [ ],
    "children" : [ ]
  }, {
    "dbId" : 10876444,
    "stId" : "R-DME-5218731-2",
    "displayName" : "phospho-p-T497-PRKCA [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 56210,
    "identifier" : "P13677",
    "standardIdentifier" : "uniprot:P13677",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 10876446 ],
    "children" : [ ]
  }, {
    "dbId" : 29370,
    "stId" : "R-ALL-29370",
    "displayName" : "ADP [cytosol]",
    "schemaClass" : "SimpleEntity",
    "speciesId" : 0,
    "diagramIds" : [ 34514, 34498, 34579, 34565, 34519, 34585, 34569, 34538, 34590, 34527, 34559 ],
    "identifier" : "456216",
    "standardIdentifier" : "chebi:456216",
    "referenceType" : "ReferenceMolecule",
    "parents" : [ ],
    "children" : [ ]
  }, {
    "dbId" : 10876446,
    "stId" : "R-DME-5218731-3",
    "displayName" : "Homologues of p-T497-PRKCA [cytosol]",
    "schemaClass" : "DefinedSet",
    "speciesId" : 56210,
    "parents" : [ 10876458 ],
    "children" : [ 10876441, 10876444 ]
  }, {
    "dbId" : 10876441,
    "stId" : "R-DME-5218731",
    "displayName" : "phospho-p-T497-PRKCA [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 56210,
    "identifier" : "P05130",
    "standardIdentifier" : "uniprot:P05130",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 10876446 ],
    "children" : [ ]
  }, {
    "dbId" : 10876517,
    "stId" : "R-DME-5218789",
    "displayName" : "p-VAV family:PIP3 [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 56210,
    "diagramIds" : [ 34593 ],
    "parents" : [ 10876543, 10876541 ],
    "children" : [ 179838, 10853218 ]
  }, {
    "dbId" : 10849380,
    "stId" : "R-DME-211604-2",
    "displayName" : "PAK2 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 56210,
    "identifier" : "Q9VI13",
    "standardIdentifier" : "uniprot:Q9VI13",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Pak", "DPAK", "Dpak1", "CG10295" ],
    "parents" : [ 10849382 ],
    "children" : [ ]
  }, {
    "dbId" : 10876519,
    "stId" : "R-DME-58218",
    "displayName" : "PRKCZ [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 56210,
    "identifier" : "A1Z9X0",
    "standardIdentifier" : "uniprot:A1Z9X0",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 10876521 ],
    "children" : [ ]
  }, {
    "dbId" : 10849382,
    "stId" : "R-DME-211604-3",
    "displayName" : "Homologues of PAK2 [cytosol]",
    "schemaClass" : "DefinedSet",
    "speciesId" : 56210,
    "parents" : [ 10849392, 10849384 ],
    "children" : [ 10849378, 10849380 ]
  }, {
    "dbId" : 10876512,
    "stId" : "R-DME-5218777",
    "displayName" : "VEGFA dimer:p-6Y-VEGFR2 dimer:PI3K [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 56210,
    "diagramIds" : [ 34500, 34631 ],
    "parents" : [ ],
    "children" : [ 10876510, 10833847 ]
  }, {
    "dbId" : 10849376,
    "stId" : "R-DME-445002",
    "displayName" : "PAK1 dimer [cytosol]",
    "schemaClass" : "Complex",
    "speciesId" : 56210,
    "parents" : [ 10849390 ],
    "children" : [ 10849374 ]
  }, {
    "dbId" : 10868834,
    "stId" : "R-DME-5674631",
    "displayName" : "RAC1:GDP [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 56210,
    "diagramIds" : [ 34594 ],
    "parents" : [ 10876541 ],
    "children" : [ 29420, 351103 ]
  }, {
    "dbId" : 10849378,
    "stId" : "R-DME-211604",
    "displayName" : "PAK2 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 56210,
    "identifier" : "A0A0B4KGS4",
    "standardIdentifier" : "uniprot:A0A0B4KGS4",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 10849382 ],
    "children" : [ ]
  }, {
    "dbId" : 10849388,
    "stId" : "R-DME-5669154",
    "displayName" : "PAK3 dimer [cytosol]",
    "schemaClass" : "Complex",
    "speciesId" : 56210,
    "parents" : [ 10849390 ],
    "children" : [ 10849386 ]
  }, {
    "dbId" : 10876527,
    "stId" : "R-DME-5218716",
    "displayName" : "phospho-Sk1 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 56210,
    "diagramIds" : [ 34578 ],
    "identifier" : "Q9VYY8",
    "standardIdentifier" : "uniprot:Q9VYY8",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Sk1" ],
    "parents" : [ ],
    "children" : [ ]
  }, {
    "dbId" : 29386,
    "stId" : "R-ALL-29386",
    "displayName" : "FAD [cytosol]",
    "schemaClass" : "SimpleEntity",
    "speciesId" : 0,
    "identifier" : "57692",
    "standardIdentifier" : "chebi:57692",
    "referenceType" : "ReferenceMolecule",
    "parents" : [ 10843923, 10843887 ],
    "children" : [ ]
  }, {
    "dbId" : 10849390,
    "stId" : "R-DME-399856",
    "displayName" : "PAK1,2,3 dimer [cytosol]",
    "schemaClass" : "DefinedSet",
    "speciesId" : 56210,
    "diagramIds" : [ 34507 ],
    "parents" : [ 10877196 ],
    "children" : [ 10849384, 10849388, 10849376 ]
  }, {
    "dbId" : 10876521,
    "stId" : "R-DME-5218761",
    "displayName" : "PKCA,PKCB,PKCD,PKCZ [cytosol]",
    "schemaClass" : "DefinedSet",
    "speciesId" : 56210,
    "diagramIds" : [ 34563 ],
    "parents" : [ ],
    "children" : [ 10836635, 10837185, 10836630, 10876519 ]
  }, {
    "dbId" : 10849384,
    "stId" : "R-DME-2685645",
    "displayName" : "PAK2 dimer [cytosol]",
    "schemaClass" : "Complex",
    "speciesId" : 56210,
    "parents" : [ 10849390 ],
    "children" : [ 10849382 ]
  }, {
    "dbId" : 10849386,
    "stId" : "R-DME-428457",
    "displayName" : "PAK3 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 56210,
    "identifier" : "Q9VI13",
    "standardIdentifier" : "uniprot:Q9VI13",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Pak", "DPAK", "Dpak1", "CG10295" ],
    "parents" : [ 10849392, 10849388 ],
    "children" : [ ]
  }, {
    "dbId" : 10868854,
    "stId" : "R-DME-442574",
    "displayName" : "IRSp53 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 56210,
    "diagramIds" : [ 34490 ],
    "identifier" : "Q8IQE6",
    "standardIdentifier" : "uniprot:Q8IQE6",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "IRSp53" ],
    "parents" : [ 10868906 ],
    "children" : [ ]
  }, {
    "dbId" : 10849392,
    "stId" : "R-DME-390765",
    "displayName" : "PAK1,2,3 [cytosol]",
    "schemaClass" : "DefinedSet",
    "speciesId" : 56210,
    "parents" : [ 10877198 ],
    "children" : [ 10849386, 10849374, 10849382 ]
  }, {
    "dbId" : 10913392,
    "stId" : "R-DME-9833482",
    "displayName" : "PKR-mediated signaling",
    "schemaClass" : "Pathway",
    "speciesId" : 56210,
    "diagramIds" : [ 34683 ]
  }, {
    "dbId" : 10876541,
    "stId" : "R-DME-8951587",
    "displayName" : "p-VAV family:PIP3:RAC1:GDP [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 56210,
    "diagramIds" : [ 34502 ],
    "parents" : [ ],
    "children" : [ 10868834, 10876517 ]
  }, {
    "dbId" : 10839165,
    "stId" : "R-DME-198356",
    "displayName" : "phospho-p-T308,S473-AKT1 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 56210,
    "diagramIds" : [ 34533 ],
    "identifier" : "Q8INB9",
    "standardIdentifier" : "uniprot:Q8INB9",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Akt", "Akt1", "CG4006" ],
    "parents" : [ 10843925 ],
    "children" : [ ]
  }, {
    "dbId" : 10876543,
    "stId" : "R-DME-5218784",
    "displayName" : "p-VAV family:PIP3:RAC1:GTP [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 56210,
    "diagramIds" : [ 34504 ],
    "parents" : [ 10877196, 10877198 ],
    "children" : [ 351067, 10876517 ]
  }, {
    "dbId" : 10876536,
    "stId" : "R-DME-5218802",
    "displayName" : "RASA1:p21 RAS:GTP:SPG [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 56210,
    "diagramIds" : [ 34582 ],
    "parents" : [ ],
    "children" : [ 10841179, 1606609, 10840037 ]
  }, {
    "dbId" : 10868859,
    "stId" : "R-DME-200979",
    "displayName" : "Hem [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 56210,
    "identifier" : "P55162",
    "standardIdentifier" : "uniprot:P55162",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Hem" ],
    "parents" : [ 10868904 ],
    "children" : [ ]
  }, {
    "dbId" : 10876485,
    "stId" : "R-DME-5218758",
    "displayName" : "p-PKC [cytosol]",
    "schemaClass" : "DefinedSet",
    "speciesId" : 56210,
    "diagramIds" : [ 34570 ],
    "parents" : [ 10876492 ],
    "children" : [ 10876473, 10876461, 10876483, 10876471 ]
  }, {
    "dbId" : 10876481,
    "stId" : "R-DME-4332337-2",
    "displayName" : "phospho-p-T497,T638,S657-PRKCA [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 56210,
    "identifier" : "P13677",
    "standardIdentifier" : "uniprot:P13677",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 10876483 ],
    "children" : [ ]
  }, {
    "dbId" : 10876483,
    "stId" : "R-DME-4332337-3",
    "displayName" : "Homologues of p-T497,T638,S657-PRKCA [cytosol]",
    "schemaClass" : "DefinedSet",
    "speciesId" : 56210,
    "parents" : [ 10876485 ],
    "children" : [ 10876477, 10876481 ]
  }, {
    "dbId" : 29926,
    "stId" : "R-ALL-29926",
    "displayName" : "Mg2+ [cytosol]",
    "schemaClass" : "SimpleEntity",
    "speciesId" : 0,
    "identifier" : "18420",
    "standardIdentifier" : "chebi:18420",
    "referenceType" : "ReferenceMolecule",
    "parents" : [ 10841263, 10874565 ],
    "children" : [ ]
  }, {
    "dbId" : 10876492,
    "stId" : "R-DME-5218773",
    "displayName" : "DAG:active PKC:Ca+2 [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 56210,
    "diagramIds" : [ 34574 ],
    "parents" : [ ],
    "children" : [ 112275, 74016, 10876485 ]
  }, {
    "dbId" : 29420,
    "stId" : "R-ALL-29420",
    "displayName" : "GDP [cytosol]",
    "schemaClass" : "SimpleEntity",
    "speciesId" : 0,
    "diagramIds" : [ 34505 ],
    "identifier" : "58189",
    "standardIdentifier" : "chebi:58189",
    "referenceType" : "ReferenceMolecule",
    "parents" : [ 10868834 ],
    "children" : [ ]
  }, {
    "dbId" : 10870868,
    "stId" : "R-DME-2317313",
    "displayName" : "p-S-AKT:PDPK1:PIP3 [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 56210,
    "diagramIds" : [ 34531 ],
    "parents" : [ ],
    "children" : [ 10842952, 10835903 ]
  }, {
    "dbId" : 10871895,
    "stId" : "R-DME-399824-2",
    "displayName" : "phospho-p-S141,T402-PAK2 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 56210,
    "identifier" : "Q9VI13",
    "standardIdentifier" : "uniprot:Q9VI13",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Pak", "DPAK", "Dpak1", "CG10295" ],
    "parents" : [ 10871897 ],
    "children" : [ ]
  }, {
    "dbId" : 29426,
    "stId" : "R-ALL-29426",
    "displayName" : "Zn2+ [cytosol]",
    "schemaClass" : "SimpleEntity",
    "speciesId" : 0,
    "identifier" : "29105",
    "standardIdentifier" : "chebi:29105",
    "referenceType" : "ReferenceMolecule",
    "parents" : [ 10843923, 10843887 ],
    "children" : [ ]
  }, {
    "dbId" : 10836566,
    "stId" : "R-DME-74294",
    "displayName" : "CALM1:4xCa2+ [cytosol]",
    "schemaClass" : "Complex",
    "speciesId" : 56210,
    "parents" : [ 10843925 ],
    "children" : [ 10831697, 74016 ]
  }, {
    "dbId" : 10876496,
    "stId" : "R-DME-4420127",
    "displayName" : "Ghost homologue of VEGFA-165 [extracellular region]",
    "schemaClass" : "GenomeEncodedEntity",
    "speciesId" : 56210,
    "parents" : [ 10876498 ],
    "children" : [ ]
  }, {
    "dbId" : 10871891,
    "stId" : "R-DME-399824",
    "displayName" : "phospho-p-S141,T402-PAK2 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 56210,
    "identifier" : "A0A0B4KGS4",
    "standardIdentifier" : "uniprot:A0A0B4KGS4",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 10871897 ],
    "children" : [ ]
  }, {
    "dbId" : 10876498,
    "stId" : "R-DME-4420158",
    "displayName" : "VEGFA-165 dimer [extracellular region]",
    "schemaClass" : "Complex",
    "speciesId" : 56210,
    "parents" : [ 10876510 ],
    "children" : [ 10876496 ]
  }, {
    "dbId" : 10912862,
    "stId" : "R-DME-5673001",
    "displayName" : "RAF/MAP kinase cascade",
    "schemaClass" : "Pathway",
    "speciesId" : 56210,
    "diagramIds" : [ 34672 ]
  }, {
    "dbId" : 10876508,
    "stId" : "R-DME-4420096",
    "displayName" : "p-6Y-VEGFR2 dimer [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 56210,
    "parents" : [ 10876510 ],
    "children" : [ 10876506 ]
  }, {
    "dbId" : 10849372,
    "stId" : "R-DME-162629-2",
    "displayName" : "PAK1 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 56210,
    "identifier" : "Q9VI13",
    "standardIdentifier" : "uniprot:Q9VI13",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Pak", "DPAK", "Dpak1", "CG10295" ],
    "parents" : [ 10849374 ],
    "children" : [ ]
  }, {
    "dbId" : 10876510,
    "stId" : "R-DME-4420101",
    "displayName" : "VEGFA dimer:p-6Y-VEGFR2 dimer [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 56210,
    "parents" : [ 10876512 ],
    "children" : [ 10876508, 10876498 ]
  }, {
    "dbId" : 10849374,
    "stId" : "R-DME-162629-3",
    "displayName" : "Homologues of PAK1 [cytosol]",
    "schemaClass" : "DefinedSet",
    "speciesId" : 56210,
    "parents" : [ 10849392, 10849376 ],
    "children" : [ 10849368, 10849372 ]
  }, {
    "dbId" : 10871897,
    "stId" : "R-DME-399824-3",
    "displayName" : "Homologues of p-S141,T402-PAK2 [cytosol]",
    "schemaClass" : "DefinedSet",
    "speciesId" : 56210,
    "parents" : [ 10877204 ],
    "children" : [ 10871891, 10871895 ]
  }, {
    "dbId" : 10849368,
    "stId" : "R-DME-162629",
    "displayName" : "PAK1 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 56210,
    "identifier" : "A0A0B4KGS4",
    "standardIdentifier" : "uniprot:A0A0B4KGS4",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 10849374 ],
    "children" : [ ]
  }, {
    "dbId" : 29438,
    "stId" : "R-ALL-29438",
    "displayName" : "GTP [cytosol]",
    "schemaClass" : "SimpleEntity",
    "speciesId" : 0,
    "diagramIds" : [ 34503 ],
    "identifier" : "37565",
    "standardIdentifier" : "chebi:37565",
    "referenceType" : "ReferenceMolecule",
    "parents" : [ 10874565, 10837160, 10840037, 351067 ],
    "children" : [ ]
  }, {
    "dbId" : 10841179,
    "stId" : "R-DME-186833",
    "displayName" : "vap [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 56210,
    "diagramIds" : [ 34584 ],
    "identifier" : "Q8IR23",
    "standardIdentifier" : "uniprot:Q8IR23",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "vap" ],
    "parents" : [ 10876536 ],
    "children" : [ ]
  }, {
    "dbId" : 10876506,
    "stId" : "R-DME-4420103",
    "displayName" : "phospho-p-6Y-VEGFR2 [plasma membrane]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 56210,
    "identifier" : "E1JHB7",
    "standardIdentifier" : "uniprot:E1JHB7",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 10876508 ],
    "children" : [ ]
  }, {
    "dbId" : 10833839,
    "stId" : "R-DME-74789",
    "displayName" : "Pi3K21B [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 56210,
    "identifier" : "Q7KTZ2",
    "standardIdentifier" : "uniprot:Q7KTZ2",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Pi3K21B" ],
    "parents" : [ 10833847 ],
    "children" : [ ]
  }, {
    "dbId" : 10833845,
    "stId" : "R-DME-74788",
    "displayName" : "Pi3K92E [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 56210,
    "identifier" : "P91634",
    "standardIdentifier" : "uniprot:P91634",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Pi3K92E", "CG4141", "Dmel_CG4141" ],
    "parents" : [ 10833847 ],
    "children" : [ ]
  }, {
    "dbId" : 29968,
    "stId" : "R-ALL-29968",
    "displayName" : "L-Cit [cytosol]",
    "schemaClass" : "SimpleEntity",
    "speciesId" : 0,
    "diagramIds" : [ 34551 ],
    "identifier" : "57743",
    "standardIdentifier" : "chebi:57743",
    "referenceType" : "ReferenceMolecule",
    "parents" : [ ],
    "children" : [ ]
  }, {
    "dbId" : 10833847,
    "stId" : "R-DME-74693",
    "displayName" : "PI3K [cytosol]",
    "schemaClass" : "Complex",
    "speciesId" : 56210,
    "parents" : [ 10876512 ],
    "children" : [ 10833839, 10833845 ]
  }, {
    "dbId" : 10835901,
    "stId" : "R-DME-61459",
    "displayName" : "PDPK1 [plasma membrane]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 56210,
    "diagramIds" : [ 34566 ],
    "identifier" : "Q9W0V1",
    "standardIdentifier" : "uniprot:Q9W0V1",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Pdk1", "Pk61C", "CG1210" ],
    "parents" : [ 10835903 ],
    "children" : [ ]
  }, {
    "dbId" : 10835903,
    "stId" : "R-DME-109697",
    "displayName" : "PDPK1:PIP3 [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 56210,
    "diagramIds" : [ 34522 ],
    "parents" : [ 10870868 ],
    "children" : [ 179838, 10835901 ]
  }, {
    "dbId" : 29468,
    "stId" : "R-ALL-29468",
    "displayName" : "L-Arg [cytosol]",
    "schemaClass" : "SimpleEntity",
    "speciesId" : 0,
    "diagramIds" : [ 34546 ],
    "identifier" : "32682",
    "standardIdentifier" : "chebi:32682",
    "referenceType" : "ReferenceMolecule",
    "parents" : [ ],
    "children" : [ ]
  }, {
    "dbId" : 74016,
    "stId" : "R-ALL-74016",
    "displayName" : "Ca2+ [cytosol]",
    "schemaClass" : "SimpleEntity",
    "speciesId" : 0,
    "diagramIds" : [ 34573 ],
    "identifier" : "29108",
    "standardIdentifier" : "chebi:29108",
    "referenceType" : "ReferenceMolecule",
    "parents" : [ 10876492, 10836566 ],
    "children" : [ ]
  }, {
    "dbId" : 73524,
    "stId" : "R-ALL-73524",
    "displayName" : "FMN [cytosol]",
    "schemaClass" : "SimpleEntity",
    "speciesId" : 0,
    "identifier" : "58210",
    "standardIdentifier" : "chebi:58210",
    "referenceType" : "ReferenceMolecule",
    "parents" : [ 10843923, 10843887 ],
    "children" : [ ]
  }, {
    "dbId" : 10840037,
    "stId" : "R-DME-109783",
    "displayName" : "p21 RAS:GTP [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 56210,
    "diagramIds" : [ 34586 ],
    "parents" : [ 10876536 ],
    "children" : [ 10840035, 29438 ]
  }, {
    "dbId" : 10840033,
    "stId" : "R-DME-9647815",
    "displayName" : "S-Farn-Me KRAS4B [plasma membrane]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 56210,
    "identifier" : "P08646",
    "standardIdentifier" : "uniprot:P08646",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Ras85D", "Ras1", "CG9375" ],
    "parents" : [ 10840035 ],
    "children" : [ ]
  }, {
    "dbId" : 10844129,
    "stId" : "R-DME-201861",
    "displayName" : "Act5C [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 56210,
    "identifier" : "P10987",
    "standardIdentifier" : "uniprot:P10987",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Act5C" ],
    "parents" : [ 10844131 ],
    "children" : [ ]
  }, {
    "dbId" : 10840035,
    "stId" : "R-DME-9649715",
    "displayName" : "mature p21 RAS [plasma membrane]",
    "schemaClass" : "DefinedSet",
    "speciesId" : 56210,
    "parents" : [ 10840037 ],
    "children" : [ 10840027, 10840024, 10840030, 10840033 ]
  }, {
    "dbId" : 10844131,
    "stId" : "R-DME-201857",
    "displayName" : "G-actin [cytosol]",
    "schemaClass" : "Complex",
    "speciesId" : 56210,
    "parents" : [ 10849939 ],
    "children" : [ 113592, 10844129 ]
  }, {
    "dbId" : 351067,
    "stId" : "R-DME-351067",
    "displayName" : "RAC1:GTP [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 56210,
    "diagramIds" : [ 34493 ],
    "parents" : [ 10876543, 10868906 ],
    "children" : [ 29438, 351103 ]
  }, {
    "dbId" : 10849729,
    "stId" : "R-DME-391267",
    "displayName" : "Sk1 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 56210,
    "diagramIds" : [ 34577 ],
    "identifier" : "Q9VYY8",
    "standardIdentifier" : "uniprot:Q9VYY8",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Sk1" ],
    "parents" : [ ],
    "children" : [ ]
  }, {
    "dbId" : 140648,
    "stId" : "R-ALL-140648",
    "displayName" : "Ca2+ [plasma membrane]",
    "schemaClass" : "SimpleEntity",
    "speciesId" : 0,
    "identifier" : "29108",
    "standardIdentifier" : "chebi:29108",
    "referenceType" : "ReferenceMolecule",
    "parents" : [ 10843905 ],
    "children" : [ ]
  }, {
    "dbId" : 351103,
    "stId" : "R-DME-351103",
    "displayName" : "RAC1 [plasma membrane]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 56210,
    "identifier" : "P40792",
    "standardIdentifier" : "uniprot:P40792",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Rac1", "RacA", "CG2248" ],
    "parents" : [ 10868834, 351067 ],
    "children" : [ ]
  }, {
    "dbId" : 10840030,
    "stId" : "R-DME-9647912",
    "displayName" : "S-Farn-Me-2xPalmS HRAS [plasma membrane]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 56210,
    "identifier" : "P08646",
    "standardIdentifier" : "uniprot:P08646",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Ras85D", "Ras1", "CG9375" ],
    "parents" : [ 10840035 ],
    "children" : [ ]
  }, {
    "dbId" : 10840024,
    "stId" : "R-DME-9647915",
    "displayName" : "S-Farn-Me-PalmS KRAS4A [plasma membrane]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 56210,
    "identifier" : "P08646",
    "standardIdentifier" : "uniprot:P08646",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Ras85D", "Ras1", "CG9375" ],
    "parents" : [ 10840035 ],
    "children" : [ ]
  }, {
    "dbId" : 10840027,
    "stId" : "R-DME-9647910",
    "displayName" : "S-Farn-Me PalmS NRAS [plasma membrane]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 56210,
    "identifier" : "P08646",
    "standardIdentifier" : "uniprot:P08646",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Ras85D", "Ras1", "CG9375" ],
    "parents" : [ 10840035 ],
    "children" : [ ]
  }, {
    "dbId" : 10877221,
    "stId" : "R-DME-5357454",
    "displayName" : "VE-cadherin-Catenin complex [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 56210,
    "diagramIds" : [ 34517 ],
    "parents" : [ ],
    "children" : [ 10877209, 10850493, 10877219, 10877217 ]
  }, {
    "dbId" : 10877223,
    "stId" : "R-DME-5357435",
    "displayName" : "Ghost homologue of p-S665-VE-cadherin [plasma membrane]",
    "schemaClass" : "GenomeEncodedEntity",
    "speciesId" : 56210,
    "parents" : [ 10877225 ],
    "children" : [ ]
  }, {
    "dbId" : 10877217,
    "stId" : "R-DME-418993",
    "displayName" : "Beta-catenin/gamma catenin [plasma membrane]",
    "schemaClass" : "DefinedSet",
    "speciesId" : 56210,
    "parents" : [ 10877225, 10877221 ],
    "children" : [ 10877215, 10877213 ]
  }, {
    "dbId" : 10877219,
    "stId" : "R-DME-418992",
    "displayName" : "Ghost homologue of VE-cadherin [plasma membrane]",
    "schemaClass" : "GenomeEncodedEntity",
    "speciesId" : 56210,
    "parents" : [ 10877221 ],
    "children" : [ ]
  }, {
    "dbId" : 10853679,
    "stId" : "R-DME-399819-2",
    "displayName" : "phospho-p-S144,T423-PAK1 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 56210,
    "identifier" : "Q9VI13",
    "standardIdentifier" : "uniprot:Q9VI13",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Pak", "DPAK", "Dpak1", "CG10295" ],
    "parents" : [ 10853681 ],
    "children" : [ ]
  }, {
    "dbId" : 10877225,
    "stId" : "R-DME-5357459",
    "displayName" : "p-S665-VE-cadherin-Catenin complex [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 56210,
    "diagramIds" : [ 34518 ],
    "parents" : [ ],
    "children" : [ 10877209, 10850493, 10877217, 10877223 ]
  }, {
    "dbId" : 10853675,
    "stId" : "R-DME-399819",
    "displayName" : "phospho-p-S144,T423-PAK1 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 56210,
    "identifier" : "A0A0B4KGS4",
    "standardIdentifier" : "uniprot:A0A0B4KGS4",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 10853681 ],
    "children" : [ ]
  }, {
    "dbId" : 202124,
    "stId" : "R-ALL-202124",
    "displayName" : "NO [cytosol]",
    "schemaClass" : "SimpleEntity",
    "speciesId" : 0,
    "diagramIds" : [ 34549 ],
    "identifier" : "16480",
    "standardIdentifier" : "chebi:16480",
    "referenceType" : "ReferenceMolecule",
    "parents" : [ ],
    "children" : [ ]
  }, {
    "dbId" : 10831670,
    "stId" : "R-DME-9016707-2",
    "displayName" : "CALM1 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 56210,
    "identifier" : "P47948",
    "standardIdentifier" : "uniprot:P47948",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 10831697 ],
    "children" : [ ]
  }, {
    "dbId" : 10842934,
    "stId" : "R-DME-199416",
    "displayName" : "AKT1 [plasma membrane]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 56210,
    "identifier" : "Q8INB9",
    "standardIdentifier" : "uniprot:Q8INB9",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Akt", "Akt1", "CG4006" ],
    "parents" : [ 10842940 ],
    "children" : [ ]
  }, {
    "dbId" : 10853681,
    "stId" : "R-DME-399819-3",
    "displayName" : "Homologues of p-S144,T423-PAK1 [cytosol]",
    "schemaClass" : "DefinedSet",
    "speciesId" : 56210,
    "parents" : [ 10877204 ],
    "children" : [ 10853675, 10853679 ]
  }, {
    "dbId" : 10831665,
    "stId" : "R-DME-9016707",
    "displayName" : "CALM1 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 56210,
    "identifier" : "P47947",
    "standardIdentifier" : "uniprot:P47947",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 10831697 ],
    "children" : [ ]
  }, {
    "dbId" : 10843954,
    "stId" : "R-DME-202210",
    "displayName" : "PDPK1 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 56210,
    "diagramIds" : [ 34521 ],
    "identifier" : "Q9W0V1",
    "standardIdentifier" : "uniprot:Q9W0V1",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Pdk1", "Pk61C", "CG1210" ],
    "parents" : [ ],
    "children" : [ ]
  }, {
    "dbId" : 10842940,
    "stId" : "R-DME-202052",
    "displayName" : "AKT [plasma membrane]",
    "schemaClass" : "CandidateSet",
    "speciesId" : 56210,
    "parents" : [ 10842942 ],
    "children" : [ 10842934, 10842938, 10842936 ]
  }, {
    "dbId" : 10842942,
    "stId" : "R-DME-2317329",
    "displayName" : "AKT:PIP3 [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 56210,
    "diagramIds" : [ 34524 ],
    "parents" : [ 10842973 ],
    "children" : [ 179838, 10842940 ]
  }, {
    "dbId" : 10842936,
    "stId" : "R-DME-202053",
    "displayName" : "AKT2 [plasma membrane]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 56210,
    "identifier" : "Q8INB9",
    "standardIdentifier" : "uniprot:Q8INB9",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Akt", "Akt1", "CG4006" ],
    "parents" : [ 10842940 ],
    "children" : [ ]
  }, {
    "dbId" : 10831675,
    "stId" : "R-DME-9016707-3",
    "displayName" : "CALM1 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 56210,
    "identifier" : "P47949",
    "standardIdentifier" : "uniprot:P47949",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 10831697 ],
    "children" : [ ]
  }, {
    "dbId" : 10842938,
    "stId" : "R-DME-2976006",
    "displayName" : "AKT3 [plasma membrane]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 56210,
    "identifier" : "Q8INB9",
    "standardIdentifier" : "uniprot:Q8INB9",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Akt", "Akt1", "CG4006" ],
    "parents" : [ 10842940 ],
    "children" : [ ]
  }, {
    "dbId" : 10843910,
    "stId" : "R-DME-534996",
    "displayName" : "HSP90AA1 [plasma membrane]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 56210,
    "identifier" : "P02828",
    "standardIdentifier" : "uniprot:P02828",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 10843912 ],
    "children" : [ ]
  }, {
    "dbId" : 10843905,
    "stId" : "R-DME-534997",
    "displayName" : "CALM1:4Ca2+ [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 56210,
    "parents" : [ 10843912 ],
    "children" : [ 10843903, 140648 ]
  }, {
    "dbId" : 10877196,
    "stId" : "R-DME-5357447",
    "displayName" : "2 x p-VAV family:PIP3:RAC1:GTP:PAK 1-3 [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 56210,
    "diagramIds" : [ 34508 ],
    "parents" : [ ],
    "children" : [ 10849390, 10876543 ]
  }, {
    "dbId" : 10843916,
    "stId" : "R-DME-202113",
    "displayName" : "eNOS:CaM:HSP90:p-AKT1 [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 56210,
    "diagramIds" : [ 34535 ],
    "parents" : [ ],
    "children" : [ 10843914, 10843912 ]
  }, {
    "dbId" : 10877198,
    "stId" : "R-DME-5357487",
    "displayName" : "p-VAV family:PIP3:RAC1:GTP:PAK 1-3 [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 56210,
    "diagramIds" : [ 34510 ],
    "parents" : [ ],
    "children" : [ 10876543, 10849392 ]
  }, {
    "dbId" : 10843918,
    "stId" : "R-DME-192864",
    "displayName" : "HSP90AA1 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 56210,
    "identifier" : "P02828",
    "standardIdentifier" : "uniprot:P02828",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 10843925 ],
    "children" : [ ]
  }, {
    "dbId" : 10843912,
    "stId" : "R-DME-202105",
    "displayName" : "eNOS:CaM:HSP90 [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 56210,
    "diagramIds" : [ 34534 ],
    "parents" : [ 10843916 ],
    "children" : [ 10843887, 10843905, 10843910 ]
  }, {
    "dbId" : 10843914,
    "stId" : "R-DME-199430",
    "displayName" : "phospho-p-T308,S473-AKT1 [plasma membrane]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 56210,
    "identifier" : "Q8INB9",
    "standardIdentifier" : "uniprot:Q8INB9",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Akt", "Akt1", "CG4006" ],
    "parents" : [ 10843916 ],
    "children" : [ ]
  }, {
    "dbId" : 10843925,
    "stId" : "R-DME-202121",
    "displayName" : "p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 56210,
    "diagramIds" : [ 34539 ],
    "parents" : [ 10843930 ],
    "children" : [ 10843918, 10839165, 10843923, 10836566 ]
  }, {
    "dbId" : 10877204,
    "stId" : "R-DME-399836",
    "displayName" : "p-S,T-PAK1,2,3 [cytosol]",
    "schemaClass" : "DefinedSet",
    "speciesId" : 56210,
    "diagramIds" : [ 34513 ],
    "parents" : [ ],
    "children" : [ 10871897, 10877202, 10853681 ]
  }, {
    "dbId" : 10843921,
    "stId" : "R-DME-202139",
    "displayName" : "phospho-2xPalmC-MyrG-p-S1177-NOS3 [plasma membrane]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 56210,
    "identifier" : "Q27571",
    "standardIdentifier" : "uniprot:Q27571",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 10843923 ],
    "children" : [ ]
  }, {
    "dbId" : 10843923,
    "stId" : "R-DME-203564",
    "displayName" : "p-S1177-eNOS dimer [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 56210,
    "parents" : [ 10843925 ],
    "children" : [ 29870, 29386, 73524, 10843921, 29426, 71185 ]
  }, {
    "dbId" : 10854675,
    "stId" : "R-DME-450563",
    "displayName" : "HSPB1 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 56210,
    "identifier" : "Q8IQW5",
    "standardIdentifier" : "uniprot:Q8IQW5",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 10876548 ],
    "children" : [ ]
  }, {
    "dbId" : 10877202,
    "stId" : "R-DME-5357471",
    "displayName" : "phospho-p-S154,T436-PAK3 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 56210,
    "identifier" : "Q9VI13",
    "standardIdentifier" : "uniprot:Q9VI13",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Pak", "DPAK", "Dpak1", "CG10295" ],
    "parents" : [ 10877204 ],
    "children" : [ ]
  }, {
    "dbId" : 10877213,
    "stId" : "R-DME-191731",
    "displayName" : "beta-catenin [plasma membrane]",
    "schemaClass" : "CandidateSet",
    "speciesId" : 56210,
    "parents" : [ 10877217 ],
    "children" : [ 10877211 ]
  }, {
    "dbId" : 113592,
    "stId" : "R-ALL-113592",
    "displayName" : "ATP [cytosol]",
    "schemaClass" : "SimpleEntity",
    "speciesId" : 0,
    "diagramIds" : [ 34496, 34576, 34512, 34562, 34516, 34581, 34568, 34537, 34555, 34525, 34589 ],
    "identifier" : "30616",
    "standardIdentifier" : "chebi:30616",
    "referenceType" : "ReferenceMolecule",
    "parents" : [ 10844131 ],
    "children" : [ ]
  }, {
    "dbId" : 10877215,
    "stId" : "R-DME-437260",
    "displayName" : "arm [plasma membrane]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 56210,
    "identifier" : "P18824",
    "standardIdentifier" : "uniprot:P18824",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "arm", "CG11579" ],
    "parents" : [ 10877217 ],
    "children" : [ ]
  }, {
    "dbId" : 10877209,
    "stId" : "R-DME-418996",
    "displayName" : "p120ctn [plasma membrane]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 56210,
    "identifier" : "Q7PLI0",
    "standardIdentifier" : "uniprot:Q7PLI0",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "p120ctn" ],
    "parents" : [ 10877225, 10877221 ],
    "children" : [ ]
  }, {
    "dbId" : 10877211,
    "stId" : "R-DME-9038440",
    "displayName" : "arm [plasma membrane]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 56210,
    "identifier" : "P18824",
    "standardIdentifier" : "uniprot:P18824",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "arm", "CG11579" ],
    "parents" : [ 10877213 ],
    "children" : [ ]
  }, {
    "dbId" : 10843930,
    "stId" : "R-DME-1497830",
    "displayName" : "p-S1177-eNOS:CaM:HSP90:p-AKT1:BH4 [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 56210,
    "diagramIds" : [ 34543 ],
    "parents" : [ ],
    "children" : [ 29870, 10843925 ]
  }, {
    "dbId" : 10853218,
    "stId" : "R-DME-437946",
    "displayName" : "phospho-Vav [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 56210,
    "identifier" : "Q9NHV9",
    "standardIdentifier" : "uniprot:Q9NHV9",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Vav" ],
    "parents" : [ 10876517 ],
    "children" : [ ]
  }, {
    "dbId" : 1606609,
    "stId" : "R-ALL-1606609",
    "displayName" : "SPG [plasma membrane]",
    "schemaClass" : "SimpleEntity",
    "speciesId" : 0,
    "identifier" : "84410",
    "standardIdentifier" : "chebi:84410",
    "referenceType" : "ReferenceMolecule",
    "parents" : [ 10876536 ],
    "children" : [ ]
  }, {
    "dbId" : 5218688,
    "stId" : "R-ALL-5218688",
    "displayName" : "S1P [plasma membrane]",
    "schemaClass" : "SimpleEntity",
    "speciesId" : 0,
    "diagramIds" : [ 34583 ],
    "identifier" : "60119",
    "standardIdentifier" : "chebi:60119",
    "referenceType" : "ReferenceMolecule",
    "parents" : [ ],
    "children" : [ ]
  }, {
    "dbId" : 70106,
    "stId" : "R-ALL-70106",
    "displayName" : "H+ [cytosol]",
    "schemaClass" : "SimpleEntity",
    "speciesId" : 0,
    "diagramIds" : [ 34548, 34540 ],
    "identifier" : "15378",
    "standardIdentifier" : "chebi:15378",
    "referenceType" : "ReferenceMolecule",
    "parents" : [ ],
    "children" : [ ]
  }, {
    "dbId" : 10831685,
    "stId" : "R-DME-9016707-5",
    "displayName" : "TpnC4 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 56210,
    "identifier" : "Q7K860",
    "standardIdentifier" : "uniprot:Q7K860",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "TpnC4" ],
    "parents" : [ 10831697 ],
    "children" : [ ]
  }, {
    "dbId" : 10842948,
    "stId" : "R-DME-3009363",
    "displayName" : "phospho-p-S472-AKT3 [plasma membrane]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 56210,
    "identifier" : "Q8INB9",
    "standardIdentifier" : "uniprot:Q8INB9",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Akt", "Akt1", "CG4006" ],
    "parents" : [ 10842950 ],
    "children" : [ ]
  }, {
    "dbId" : 10842950,
    "stId" : "R-DME-2317317",
    "displayName" : "p-S-AKT [plasma membrane]",
    "schemaClass" : "CandidateSet",
    "speciesId" : 56210,
    "parents" : [ 10842952 ],
    "children" : [ 10842944, 10842946, 10842948 ]
  }, {
    "dbId" : 10842944,
    "stId" : "R-DME-377265",
    "displayName" : "phospho-p-S473-AKT1 [plasma membrane]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 56210,
    "identifier" : "Q8INB9",
    "standardIdentifier" : "uniprot:Q8INB9",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Akt", "Akt1", "CG4006" ],
    "parents" : [ 10842950 ],
    "children" : [ ]
  }, {
    "dbId" : 10831680,
    "stId" : "R-DME-9016707-4",
    "displayName" : "azot [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 56210,
    "identifier" : "Q7K049",
    "standardIdentifier" : "uniprot:Q7K049",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "azot" ],
    "parents" : [ 10831697 ],
    "children" : [ ]
  }, {
    "dbId" : 10842946,
    "stId" : "R-DME-2317312",
    "displayName" : "phospho-p-S474-AKT2 [plasma membrane]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 56210,
    "identifier" : "Q8INB9",
    "standardIdentifier" : "uniprot:Q8INB9",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Akt", "Akt1", "CG4006" ],
    "parents" : [ 10842950 ],
    "children" : [ ]
  }, {
    "dbId" : 10842957,
    "stId" : "R-DME-198632",
    "displayName" : "rictor [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 56210,
    "identifier" : "Q9VWJ6",
    "standardIdentifier" : "uniprot:Q9VWJ6",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "rictor" ],
    "parents" : [ 10842968 ],
    "children" : [ ]
  }, {
    "dbId" : 5693375,
    "stId" : "R-ALL-5693375",
    "displayName" : "ADMA [cytosol]",
    "schemaClass" : "SimpleEntity",
    "speciesId" : 0,
    "diagramIds" : [ 34553 ],
    "identifier" : "58326",
    "standardIdentifier" : "chebi:58326",
    "referenceType" : "ReferenceMolecule",
    "parents" : [ ],
    "children" : [ ]
  }, {
    "dbId" : 10831695,
    "stId" : "R-DME-9016707-7",
    "displayName" : "TpnC25D [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 56210,
    "identifier" : "Q9VMT2",
    "standardIdentifier" : "uniprot:Q9VMT2",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "TpnC25D" ],
    "parents" : [ 10831697 ],
    "children" : [ ]
  }, {
    "dbId" : 10842959,
    "stId" : "R-DME-6795323",
    "displayName" : "Ghost homologue of PRR5 [cytosol]",
    "schemaClass" : "GenomeEncodedEntity",
    "speciesId" : 56210,
    "parents" : [ 10842968 ],
    "children" : [ ]
  }, {
    "dbId" : 10842952,
    "stId" : "R-DME-2317310",
    "displayName" : "p-S-AKT:PIP3 [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 56210,
    "diagramIds" : [ 34526 ],
    "parents" : [ 10870868 ],
    "children" : [ 179838, 10842950 ]
  }, {
    "dbId" : 10831690,
    "stId" : "R-DME-9016707-6",
    "displayName" : "CG10022 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 56210,
    "identifier" : "Q8IQ15",
    "standardIdentifier" : "uniprot:Q8IQ15",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "CG10022" ],
    "parents" : [ 10831697 ],
    "children" : [ ]
  }, {
    "dbId" : 10842964,
    "stId" : "R-DME-3006620",
    "displayName" : "Sin1 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 56210,
    "identifier" : "Q9V719",
    "standardIdentifier" : "uniprot:Q9V719",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Sin1" ],
    "parents" : [ 10842966 ],
    "children" : [ ]
  }, {
    "dbId" : 10842966,
    "stId" : "R-DME-9980231",
    "displayName" : "MAPKAP1:PIP3 [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 56210,
    "parents" : [ 10842968 ],
    "children" : [ 179838, 10842964 ]
  }, {
    "dbId" : 10831697,
    "stId" : "R-DME-9016707-8",
    "displayName" : "Homologues of CALM1 [cytosol]",
    "schemaClass" : "DefinedSet",
    "speciesId" : 56210,
    "parents" : [ 10836566 ],
    "children" : [ 10831690, 10831675, 10831695, 10831680, 10831665, 10831670, 10831685 ]
  }, {
    "dbId" : 10842973,
    "stId" : "R-DME-199453",
    "displayName" : "AKT:PIP3:THEM4/TRIB3 [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 56210,
    "diagramIds" : [ 34529 ],
    "parents" : [ ],
    "children" : [ 10842971, 10842942 ]
  }, {
    "dbId" : 10853209,
    "stId" : "R-DME-194866",
    "displayName" : "RHOA [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 56210,
    "identifier" : "P48148",
    "standardIdentifier" : "uniprot:P48148",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Rho1", "CG8416" ],
    "parents" : [ 10874565 ],
    "children" : [ ]
  }, {
    "dbId" : 10842968,
    "stId" : "R-DME-9980228",
    "displayName" : "mTORC2:PIP3 [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 56210,
    "diagramIds" : [ 34528 ],
    "parents" : [ ],
    "children" : [ 10839209, 10842959, 10842957, 10842966, 10839204 ]
  }, {
    "dbId" : 10842971,
    "stId" : "R-DME-199447",
    "displayName" : "trbl [plasma membrane]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 56210,
    "identifier" : "Q9V3Z1",
    "standardIdentifier" : "uniprot:Q9V3Z1",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "trbl" ],
    "parents" : [ 10842973 ],
    "children" : [ ]
  } ],
  "edges" : [ {
    "dbId" : 10899271,
    "stId" : "R-DME-8951586",
    "displayName" : "p-VAV family:PIP3 binds RAC1:GDP",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "following" : [ 10876546 ],
    "inputs" : [ 10868834, 10876517 ],
    "outputs" : [ 10876541 ],
    "efs" : [ ],
    "diagramIds" : [ 34592 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10876643,
    "stId" : "R-DME-5228992",
    "displayName" : "ROCK1,ROCK2 are activated",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "preceding" : [ 10874850 ],
    "inputs" : [ 10850527 ],
    "outputs" : [ 10876641 ],
    "efs" : [ ],
    "diagramIds" : [ 34487 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10876515,
    "stId" : "R-DME-5218819",
    "displayName" : "VEGFA dimer:p-6Y-VEGFR2 dimer:PI3K phosphorylates PIP2 to PIP3",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "following" : [ 10868908, 10870805 ],
    "inputs" : [ 113592, 179856 ],
    "outputs" : [ 179838, 29370 ],
    "catalysts" : [ 10876512 ],
    "efs" : [ ],
    "diagramIds" : [ 34495 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10874850,
    "stId" : "R-DME-3928647",
    "displayName" : "RHOA:GTP:Mg2+ binds ROCK1,ROCK2",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "following" : [ 10876643 ],
    "inputs" : [ 10837160, 10850525 ],
    "outputs" : [ 10850527 ],
    "efs" : [ ],
    "diagramIds" : [ 34483 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10876546,
    "stId" : "R-DME-5218850",
    "displayName" : "VAV exchanges GTP for GDP on RAC1, activating it",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "preceding" : [ 10899271 ],
    "following" : [ 10877230, 10868908 ],
    "inputs" : [ 29438, 10876541 ],
    "outputs" : [ 29420, 10876543 ],
    "catalysts" : [ 10876541 ],
    "efs" : [ ],
    "diagramIds" : [ 34501 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10876524,
    "stId" : "R-DME-5218821",
    "displayName" : "PDK1 phosphorylates PKC",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "following" : [ 10876488 ],
    "inputs" : [ 10876521, 113592 ],
    "outputs" : [ 10876458, 29370 ],
    "catalysts" : [ 10835901 ],
    "efs" : [ ],
    "diagramIds" : [ 34561 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10877228,
    "stId" : "R-DME-5357477",
    "displayName" : "PAK1-3 phosphorylates VE-cadherin",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "preceding" : [ 10877207 ],
    "inputs" : [ 113592, 10877221 ],
    "outputs" : [ 10877225, 29370 ],
    "catalysts" : [ 10877204 ],
    "efs" : [ ],
    "diagramIds" : [ 34515 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10868908,
    "stId" : "R-DME-2029465",
    "displayName" : "RAC1:GTP and PIP3 bind WAVE Regulatory Complex (WRC)",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "preceding" : [ 10876546, 10876515 ],
    "inputs" : [ 351067, 10868904, 179838, 10868854 ],
    "outputs" : [ 10868906 ],
    "efs" : [ ],
    "diagramIds" : [ 34489 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10876494,
    "stId" : "R-DME-5218813",
    "displayName" : "DAG and Ca+2 bind to PKC and tether it to membrane",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "preceding" : [ 10876488 ],
    "following" : [ 10876530 ],
    "inputs" : [ 112275, 74016, 10876485 ],
    "outputs" : [ 10876492 ],
    "efs" : [ ],
    "diagramIds" : [ 34571 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10877230,
    "stId" : "R-DME-5357483",
    "displayName" : "RAC1 binds PAK1-3",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "preceding" : [ 10876546 ],
    "following" : [ 10877200 ],
    "inputs" : [ 10849390, 10876543 ],
    "outputs" : [ 10877196 ],
    "efs" : [ ],
    "diagramIds" : [ 34506 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10876558,
    "stId" : "R-DME-5218916",
    "displayName" : "p-MAPK2/3 phosphorylates HSP27",
    "schemaClass" : "BlackBoxEvent",
    "speciesId" : 0,
    "preceding" : [ 10841266 ],
    "inputs" : [ 113592, 10876550 ],
    "outputs" : [ 10876555, 29370, 10849939 ],
    "catalysts" : [ 10841249 ],
    "efs" : [ ],
    "diagramIds" : [ 34554 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10876488,
    "stId" : "R-DME-5218805",
    "displayName" : "PKC autophosphorylates",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "preceding" : [ 10876524 ],
    "following" : [ 10876494 ],
    "inputs" : [ 10876458, 113592 ],
    "outputs" : [ 29370, 10876485 ],
    "catalysts" : [ 10876458 ],
    "efs" : [ ],
    "diagramIds" : [ 34567 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10843946,
    "stId" : "R-DME-202137",
    "displayName" : "AKT1 binds eNOS complex via HSP90",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "following" : [ 10843928 ],
    "inputs" : [ 10843912, 10839165 ],
    "outputs" : [ 10843916 ],
    "catalysts" : [ 10843912 ],
    "efs" : [ ],
    "diagramIds" : [ 34532 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10862826,
    "stId" : "R-DME-1497784",
    "displayName" : "The cofactor BH4 is required for electron transfer in the eNOS catalytic cycle",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "preceding" : [ 10843928 ],
    "following" : [ 10843933 ],
    "inputs" : [ 29870, 10843925 ],
    "outputs" : [ 10843930 ],
    "catalysts" : [ 10843925 ],
    "efs" : [ ],
    "diagramIds" : [ 34541 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10870805,
    "stId" : "R-DME-2316429",
    "displayName" : "PIP3 recruits PDPK1 to the membrane",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "preceding" : [ 10876515 ],
    "following" : [ 10870870 ],
    "inputs" : [ 179838, 10843954 ],
    "outputs" : [ 10835903 ],
    "efs" : [ ],
    "diagramIds" : [ 34520 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10877207,
    "stId" : "R-DME-5357472",
    "displayName" : "PAK1-3 autophosphorylates",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "preceding" : [ 10877200 ],
    "following" : [ 10877228 ],
    "inputs" : [ 10877198, 113592 ],
    "outputs" : [ 10876543, 29370, 10877204 ],
    "catalysts" : [ 10849390 ],
    "efs" : [ ],
    "diagramIds" : [ 34511 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10870870,
    "stId" : "R-DME-2317314",
    "displayName" : "AKT binds PDPK1",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "preceding" : [ 10842975, 10870805 ],
    "inputs" : [ 10842952, 10835903 ],
    "outputs" : [ 10870868 ],
    "efs" : [ ],
    "diagramIds" : [ 34530 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10877200,
    "stId" : "R-DME-5357445",
    "displayName" : "PAK1-3 dimer disassociates",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "preceding" : [ 10877230 ],
    "following" : [ 10877207 ],
    "inputs" : [ 10877196 ],
    "outputs" : [ 10877198 ],
    "efs" : [ ],
    "diagramIds" : [ 34509 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10876530,
    "stId" : "R-DME-5218823",
    "displayName" : "PKC phosphorylates sphingosine kinase 1",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "preceding" : [ 10876494 ],
    "following" : [ 10876539 ],
    "inputs" : [ 113592, 10849729 ],
    "outputs" : [ 29370, 10876527 ],
    "catalysts" : [ 10876492 ],
    "efs" : [ ],
    "diagramIds" : [ 34575 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10841266,
    "stId" : "R-DME-187688",
    "displayName" : "p38 MAPK phosphorylates MAPKAPK2, MAPKAPK3",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "following" : [ 10876558 ],
    "inputs" : [ 113592, 10841238 ],
    "outputs" : [ 29370, 10841249 ],
    "catalysts" : [ 10841263 ],
    "efs" : [ ],
    "diagramIds" : [ 34587 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10843933,
    "stId" : "R-DME-202127",
    "displayName" : "eNOS synthesizes NO",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "preceding" : [ 10862826 ],
    "inputs" : [ 29468, 70106, 29368, 29364 ],
    "outputs" : [ 202124, 29356, 29366, 29968 ],
    "catalysts" : [ 10843930 ],
    "efs" : [ ],
    "inhibitors" : [ 5693375 ],
    "diagramIds" : [ 34544 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10842975,
    "stId" : "R-DME-198640",
    "displayName" : "mTORC2 phosphorylates AKT at S473",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "following" : [ 10870870 ],
    "inputs" : [ 10842942, 113592 ],
    "outputs" : [ 10842952, 29370 ],
    "catalysts" : [ 10842968 ],
    "efs" : [ ],
    "inhibitors" : [ 10842973 ],
    "diagramIds" : [ 34523 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10843928,
    "stId" : "R-DME-202111",
    "displayName" : "AKT1 phosphorylates eNOS",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "preceding" : [ 10843946 ],
    "following" : [ 10862826 ],
    "inputs" : [ 113592, 10843916 ],
    "outputs" : [ 70106, 29370, 10843925 ],
    "catalysts" : [ 10843916 ],
    "efs" : [ ],
    "diagramIds" : [ 34536 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10876539,
    "stId" : "R-DME-5218845",
    "displayName" : "p-SPHK1 phosphorylates sphingosine to sphingosine 1-phosphate",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "preceding" : [ 10876530 ],
    "inputs" : [ 10876536, 113592 ],
    "outputs" : [ 5218688, 10841179, 29370, 10840037 ],
    "catalysts" : [ 10876527 ],
    "efs" : [ ],
    "diagramIds" : [ 34580 ],
    "entityFunctionalStatus" : [ ]
  } ],
  "subpathways" : [ {
    "dbId" : 10912726,
    "stId" : "R-DME-5218921",
    "displayName" : "VEGFR2 mediated cell proliferation",
    "events" : [ 10876530, 10876524, 10876494, 10876488, 10876539 ]
  }, {
    "dbId" : 10911446,
    "stId" : "R-DME-4420097",
    "displayName" : "VEGFA-VEGFR2 Pathway",
    "events" : [ 10876530, 10876524, 10876494, 10876488, 10876539, 10899271, 10876643, 10876515, 10870805, 10877207, 10870870, 10877200, 10843933, 10877228, 10842975, 10877230, 10843928, 10843946, 10862826, 10874850, 10876546, 10841266, 10868908, 10876558 ]
  }, {
    "dbId" : 10911584,
    "stId" : "R-DME-5218920",
    "displayName" : "VEGFR2 mediated vascular permeability",
    "events" : [ 10870805, 10877207, 10870870, 10877200, 10843933, 10877228, 10842975, 10877230, 10843928, 10843946, 10862826 ]
  } ]
}