{
  "dbId" : 10911078,
  "stId" : "R-DME-109606",
  "speciesName" : "Drosophila melanogaster",
  "nodes" : [ {
    "dbId" : 10840100,
    "stId" : "R-DME-109844",
    "displayName" : "p-T202, Y204 MAPK3 dimer [cytosol]",
    "schemaClass" : "Complex",
    "speciesId" : 56210,
    "parents" : [ 10840104 ],
    "children" : [ 10835972 ]
  }, {
    "dbId" : 10837030,
    "stId" : "R-DME-53259",
    "displayName" : "CYCS [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 56210,
    "identifier" : "P04657",
    "standardIdentifier" : "uniprot:P04657",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 10837037 ],
    "children" : [ ]
  }, {
    "dbId" : 10840102,
    "stId" : "R-DME-109855",
    "displayName" : "p-T185,Y187 MAPK1 dimer [cytosol]",
    "schemaClass" : "Complex",
    "speciesId" : 56210,
    "parents" : [ 10840104 ],
    "children" : [ 10835990 ]
  }, {
    "dbId" : 10837025,
    "stId" : "R-DME-50099",
    "displayName" : "Dark [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 56210,
    "identifier" : "Q7KLI1",
    "standardIdentifier" : "uniprot:Q7KLI1",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Dark" ],
    "parents" : [ 10837065, 10837067, 10837039 ],
    "children" : [ ]
  }, {
    "dbId" : 10837037,
    "stId" : "R-DME-53259-3",
    "displayName" : "Homologues of CYCS [cytosol]",
    "schemaClass" : "DefinedSet",
    "speciesId" : 56210,
    "diagramIds" : [ 37667 ],
    "parents" : [ 10837069, 10837039 ],
    "children" : [ 10837035, 10837030 ]
  }, {
    "dbId" : 10837039,
    "stId" : "R-DME-114253",
    "displayName" : "APAF1:CYCS [cytosol]",
    "schemaClass" : "Complex",
    "speciesId" : 56210,
    "parents" : [ 10837093, 10837049 ],
    "children" : [ 10837037, 10837025 ]
  }, {
    "dbId" : 10840104,
    "stId" : "R-DME-1268261",
    "displayName" : "p-T,Y MAPK dimers [cytosol]",
    "schemaClass" : "DefinedSet",
    "speciesId" : 56210,
    "diagramIds" : [ 37708 ],
    "parents" : [ ],
    "children" : [ 10840102, 10840100 ]
  }, {
    "dbId" : 10837035,
    "stId" : "R-DME-53259-2",
    "displayName" : "CYCS [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 56210,
    "identifier" : "P84029",
    "standardIdentifier" : "uniprot:P84029",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 10837037 ],
    "children" : [ ]
  }, {
    "dbId" : 10837045,
    "stId" : "R-DME-141639",
    "displayName" : "Dredd [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 56210,
    "identifier" : "Q8IRY7",
    "standardIdentifier" : "uniprot:Q8IRY7",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Dredd", "DCP2", "CG7486" ],
    "parents" : [ 10837047 ],
    "children" : [ ]
  }, {
    "dbId" : 10837047,
    "stId" : "R-DME-141640",
    "displayName" : "Cleaved Caspase-9 [cytosol]",
    "schemaClass" : "Complex",
    "speciesId" : 56210,
    "parents" : [ 10837049 ],
    "children" : [ 10837043, 10837045 ]
  }, {
    "dbId" : 10837043,
    "stId" : "R-DME-141638",
    "displayName" : "Dredd [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 56210,
    "identifier" : "Q8IRY7",
    "standardIdentifier" : "uniprot:Q8IRY7",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Dredd", "DCP2", "CG7486" ],
    "parents" : [ 10837047 ],
    "children" : [ ]
  }, {
    "dbId" : 10891839,
    "stId" : "R-DME-6805825",
    "displayName" : "Septin4 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 56210,
    "diagramIds" : [ 37711 ],
    "identifier" : "Q0KHR7",
    "standardIdentifier" : "uniprot:Q0KHR7",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Septin4" ],
    "parents" : [ 10903273, 10903271 ],
    "children" : [ ]
  }, {
    "dbId" : 10837054,
    "stId" : "R-DME-50849",
    "displayName" : "XIAP [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 56210,
    "identifier" : "Q24306",
    "standardIdentifier" : "uniprot:Q24306",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Diap1", "Iap1", "th", "CG12284" ],
    "parents" : [ 10837060 ],
    "children" : [ ]
  }, {
    "dbId" : 10891837,
    "stId" : "R-DME-6805816",
    "displayName" : "Septin4 [mitochondrial outer membrane]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 56210,
    "diagramIds" : [ 37710 ],
    "identifier" : "Q0KHR7",
    "standardIdentifier" : "uniprot:Q0KHR7",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Septin4" ],
    "parents" : [ ],
    "children" : [ ]
  }, {
    "dbId" : 10837049,
    "stId" : "R-DME-114258",
    "displayName" : "Apoptosome [cytosol]",
    "schemaClass" : "Complex",
    "speciesId" : 56210,
    "diagramIds" : [ 37681 ],
    "parents" : [ 10903254 ],
    "children" : [ 10837039, 10837047 ]
  }, {
    "dbId" : 10837124,
    "stId" : "R-DME-141642",
    "displayName" : "Drice [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 56210,
    "identifier" : "O01382",
    "standardIdentifier" : "uniprot:O01382",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Drice" ],
    "parents" : [ 10837134 ],
    "children" : [ ]
  }, {
    "dbId" : 10836996,
    "stId" : "R-DME-141646-2",
    "displayName" : "Dcp-1 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 56210,
    "identifier" : "O02002",
    "standardIdentifier" : "uniprot:O02002",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Dcp-1" ],
    "parents" : [ 10837004 ],
    "children" : [ ]
  }, {
    "dbId" : 10835972,
    "stId" : "R-DME-109842",
    "displayName" : "phospho-p-T202,Y204-MAPK3 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 56210,
    "identifier" : "P40417",
    "standardIdentifier" : "uniprot:P40417",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 10840100 ],
    "children" : [ ]
  }, {
    "dbId" : 10837126,
    "stId" : "R-DME-141642-2",
    "displayName" : "Dcp-1 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 56210,
    "identifier" : "O02002",
    "standardIdentifier" : "uniprot:O02002",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Dcp-1" ],
    "parents" : [ 10837134 ],
    "children" : [ ]
  }, {
    "dbId" : 10836998,
    "stId" : "R-DME-141646-3",
    "displayName" : "Damm [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 56210,
    "identifier" : "Q7KHI6",
    "standardIdentifier" : "uniprot:Q7KHI6",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Damm" ],
    "parents" : [ 10837004 ],
    "children" : [ ]
  }, {
    "dbId" : 10837120,
    "stId" : "R-DME-141641-5",
    "displayName" : "Decay [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 56210,
    "identifier" : "Q9VET9",
    "standardIdentifier" : "uniprot:Q9VET9",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Decay" ],
    "parents" : [ 10837122 ],
    "children" : [ ]
  }, {
    "dbId" : 10836992,
    "stId" : "R-DME-6804299",
    "displayName" : "CASP3(1-277) dimer [cytosol]",
    "schemaClass" : "Complex",
    "speciesId" : 56210,
    "diagramIds" : [ 37683 ],
    "parents" : [ ],
    "children" : [ 10836990 ]
  }, {
    "dbId" : 10837122,
    "stId" : "R-DME-141641-6",
    "displayName" : "Homologues of CASP7(24-198) [cytosol]",
    "schemaClass" : "DefinedSet",
    "speciesId" : 56210,
    "parents" : [ 10837136 ],
    "children" : [ 10837114, 10837112, 10837118, 10837116, 10837120 ]
  }, {
    "dbId" : 10836994,
    "stId" : "R-DME-141646",
    "displayName" : "Drice [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 56210,
    "identifier" : "O01382",
    "standardIdentifier" : "uniprot:O01382",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Drice" ],
    "parents" : [ 10837004 ],
    "children" : [ ]
  }, {
    "dbId" : 10837132,
    "stId" : "R-DME-141642-5",
    "displayName" : "Decay [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 56210,
    "identifier" : "Q9VET9",
    "standardIdentifier" : "uniprot:Q9VET9",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Decay" ],
    "parents" : [ 10837134 ],
    "children" : [ ]
  }, {
    "dbId" : 10837004,
    "stId" : "R-DME-141646-6",
    "displayName" : "Homologues of CASP3(176-277) [cytosol]",
    "schemaClass" : "DefinedSet",
    "speciesId" : 56210,
    "parents" : [ 10837018 ],
    "children" : [ 10837002, 10837000, 10836994, 10836998, 10836996 ]
  }, {
    "dbId" : 10837134,
    "stId" : "R-DME-141642-6",
    "displayName" : "Homologues of CASP7(207-303) [cytosol]",
    "schemaClass" : "DefinedSet",
    "speciesId" : 56210,
    "parents" : [ 10837136 ],
    "children" : [ 10837130, 10837128, 10837132, 10837126, 10837124 ]
  }, {
    "dbId" : 10837006,
    "stId" : "R-DME-141644",
    "displayName" : "Drice [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 56210,
    "identifier" : "O01382",
    "standardIdentifier" : "uniprot:O01382",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Drice" ],
    "parents" : [ 10837016 ],
    "children" : [ ]
  }, {
    "dbId" : 10837128,
    "stId" : "R-DME-141642-3",
    "displayName" : "Damm [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 56210,
    "identifier" : "Q7KHI6",
    "standardIdentifier" : "uniprot:Q7KHI6",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Damm" ],
    "parents" : [ 10837134 ],
    "children" : [ ]
  }, {
    "dbId" : 10837000,
    "stId" : "R-DME-141646-4",
    "displayName" : "Strica [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 56210,
    "identifier" : "Q7KHK9",
    "standardIdentifier" : "uniprot:Q7KHK9",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Strica" ],
    "parents" : [ 10837004 ],
    "children" : [ ]
  }, {
    "dbId" : 10837130,
    "stId" : "R-DME-141642-4",
    "displayName" : "Strica [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 56210,
    "identifier" : "Q7KHK9",
    "standardIdentifier" : "uniprot:Q7KHK9",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Strica" ],
    "parents" : [ 10837134 ],
    "children" : [ ]
  }, {
    "dbId" : 10837002,
    "stId" : "R-DME-141646-5",
    "displayName" : "Decay [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 56210,
    "identifier" : "Q9VET9",
    "standardIdentifier" : "uniprot:Q9VET9",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Decay" ],
    "parents" : [ 10837004 ],
    "children" : [ ]
  }, {
    "dbId" : 10837012,
    "stId" : "R-DME-141644-4",
    "displayName" : "Strica [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 56210,
    "identifier" : "Q7KHK9",
    "standardIdentifier" : "uniprot:Q7KHK9",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Strica" ],
    "parents" : [ 10837016 ],
    "children" : [ ]
  }, {
    "dbId" : 10837014,
    "stId" : "R-DME-141644-5",
    "displayName" : "Decay [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 56210,
    "identifier" : "Q9VET9",
    "standardIdentifier" : "uniprot:Q9VET9",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Decay" ],
    "parents" : [ 10837016 ],
    "children" : [ ]
  }, {
    "dbId" : 10835990,
    "stId" : "R-DME-109853",
    "displayName" : "phospho-p-T185,Y187-MAPK1 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 56210,
    "identifier" : "P40417",
    "standardIdentifier" : "uniprot:P40417",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 10840102 ],
    "children" : [ ]
  }, {
    "dbId" : 10837142,
    "stId" : "R-DME-114244",
    "displayName" : "CYCS [mitochondrial intermembrane space]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 56210,
    "identifier" : "P04657",
    "standardIdentifier" : "uniprot:P04657",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 10837146 ],
    "children" : [ ]
  }, {
    "dbId" : 10837136,
    "stId" : "R-DME-6804359",
    "displayName" : "CASP7(24-198):CASP7(207-303) [cytosol]",
    "schemaClass" : "Complex",
    "speciesId" : 56210,
    "parents" : [ 10837138 ],
    "children" : [ 10837134, 10837122 ]
  }, {
    "dbId" : 10837008,
    "stId" : "R-DME-141644-2",
    "displayName" : "Dcp-1 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 56210,
    "identifier" : "O02002",
    "standardIdentifier" : "uniprot:O02002",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Dcp-1" ],
    "parents" : [ 10837016 ],
    "children" : [ ]
  }, {
    "dbId" : 10837138,
    "stId" : "R-DME-141643",
    "displayName" : "Caspase-7 [cytosol]",
    "schemaClass" : "Complex",
    "speciesId" : 56210,
    "diagramIds" : [ 37692 ],
    "parents" : [ 10837150 ],
    "children" : [ 10837136 ]
  }, {
    "dbId" : 10837010,
    "stId" : "R-DME-141644-3",
    "displayName" : "Damm [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 56210,
    "identifier" : "Q7KHI6",
    "standardIdentifier" : "uniprot:Q7KHI6",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Damm" ],
    "parents" : [ 10837016 ],
    "children" : [ ]
  }, {
    "dbId" : 113592,
    "stId" : "R-ALL-113592",
    "displayName" : "ATP [cytosol]",
    "schemaClass" : "SimpleEntity",
    "speciesId" : 0,
    "diagramIds" : [ 37684, 37669, 37705, 37690 ],
    "identifier" : "30616",
    "standardIdentifier" : "chebi:30616",
    "referenceType" : "ReferenceMolecule",
    "parents" : [ 10837067 ],
    "children" : [ ]
  }, {
    "dbId" : 10837020,
    "stId" : "R-DME-350870",
    "displayName" : "Caspase-3 [cytosol]",
    "schemaClass" : "Complex",
    "speciesId" : 56210,
    "diagramIds" : [ 37686 ],
    "parents" : [ 10903265 ],
    "children" : [ 10837018 ]
  }, {
    "dbId" : 29370,
    "stId" : "R-ALL-29370",
    "displayName" : "ADP [cytosol]",
    "schemaClass" : "SimpleEntity",
    "speciesId" : 0,
    "diagramIds" : [ 37680, 37685, 37672, 37707, 37691 ],
    "identifier" : "456216",
    "standardIdentifier" : "chebi:456216",
    "referenceType" : "ReferenceMolecule",
    "parents" : [ 10837065 ],
    "children" : [ ]
  }, {
    "dbId" : 10837150,
    "stId" : "R-DME-114308",
    "displayName" : "XIAP:Caspase-7 [cytosol]",
    "schemaClass" : "Complex",
    "speciesId" : 56210,
    "diagramIds" : [ 37696 ],
    "parents" : [ ],
    "children" : [ 10837138, 10837060 ]
  }, {
    "dbId" : 10837016,
    "stId" : "R-DME-141644-6",
    "displayName" : "Homologues of CASP3(29-175) [cytosol]",
    "schemaClass" : "DefinedSet",
    "speciesId" : 56210,
    "parents" : [ 10837018 ],
    "children" : [ 10837006, 10837010, 10837008, 10837014, 10837012 ]
  }, {
    "dbId" : 10837144,
    "stId" : "R-DME-114244-2",
    "displayName" : "CYCS [mitochondrial intermembrane space]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 56210,
    "identifier" : "P84029",
    "standardIdentifier" : "uniprot:P84029",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 10837146 ],
    "children" : [ ]
  }, {
    "dbId" : 10837018,
    "stId" : "R-DME-350888",
    "displayName" : "CASP3(29-175):CASP3(176-277) [cytosol]",
    "schemaClass" : "Complex",
    "speciesId" : 56210,
    "parents" : [ 10837020 ],
    "children" : [ 10837016, 10837004 ]
  }, {
    "dbId" : 10837146,
    "stId" : "R-DME-114244-3",
    "displayName" : "Homologues of CYCS [mitochondrial intermembrane space]",
    "schemaClass" : "DefinedSet",
    "speciesId" : 56210,
    "diagramIds" : [ 37666 ],
    "parents" : [ ],
    "children" : [ 10837144, 10837142 ]
  }, {
    "dbId" : 10837093,
    "stId" : "R-DME-6804630",
    "displayName" : "APAF1:CYCS:ATP:CASP9(1-416)dimer  [cytosol]",
    "schemaClass" : "Complex",
    "speciesId" : 56210,
    "diagramIds" : [ 37679 ],
    "parents" : [ ],
    "children" : [ 10837039, 10837091 ]
  }, {
    "dbId" : 10903271,
    "stId" : "R-DME-9627347",
    "displayName" : "SEPT4 dimer [cytosol]",
    "schemaClass" : "Complex",
    "speciesId" : 56210,
    "diagramIds" : [ 37713 ],
    "parents" : [ ],
    "children" : [ 10891839 ]
  }, {
    "dbId" : 10837091,
    "stId" : "R-DME-6804623",
    "displayName" : "CASP9(1-416) dimer [cytosol]",
    "schemaClass" : "Complex",
    "speciesId" : 56210,
    "parents" : [ 10837093 ],
    "children" : [ 10837073 ]
  }, {
    "dbId" : 10903265,
    "stId" : "R-DME-114304",
    "displayName" : "XIAP:Caspase-3 [cytosol]",
    "schemaClass" : "Complex",
    "speciesId" : 56210,
    "diagramIds" : [ 37694 ],
    "parents" : [ ],
    "children" : [ 10837020, 10837060 ]
  }, {
    "dbId" : 10837100,
    "stId" : "R-DME-57029-2",
    "displayName" : "Dcp-1 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 56210,
    "identifier" : "O02002",
    "standardIdentifier" : "uniprot:O02002",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Dcp-1" ],
    "parents" : [ 10837108 ],
    "children" : [ ]
  }, {
    "dbId" : 10837102,
    "stId" : "R-DME-57029-3",
    "displayName" : "Damm [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 56210,
    "identifier" : "Q7KHI6",
    "standardIdentifier" : "uniprot:Q7KHI6",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Damm" ],
    "parents" : [ 10837108 ],
    "children" : [ ]
  }, {
    "dbId" : 10837098,
    "stId" : "R-DME-57029",
    "displayName" : "Drice [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 56210,
    "identifier" : "O01382",
    "standardIdentifier" : "uniprot:O01382",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Drice" ],
    "parents" : [ 10837108 ],
    "children" : [ ]
  }, {
    "dbId" : 10903273,
    "stId" : "R-DME-9627441",
    "displayName" : "SEPT4 dimer:XIAP [cytosol]",
    "schemaClass" : "Complex",
    "speciesId" : 56210,
    "diagramIds" : [ 37714 ],
    "parents" : [ ],
    "children" : [ 10891839, 10837060 ]
  }, {
    "dbId" : 10837108,
    "stId" : "R-DME-57029-6",
    "displayName" : "Homologues of CASP7(2-303) [cytosol]",
    "schemaClass" : "DefinedSet",
    "speciesId" : 56210,
    "parents" : [ 10837110 ],
    "children" : [ 10837098, 10837102, 10837100, 10837106, 10837104 ]
  }, {
    "dbId" : 10836980,
    "stId" : "R-DME-57021",
    "displayName" : "Drice [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 56210,
    "identifier" : "O01382",
    "standardIdentifier" : "uniprot:O01382",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Drice" ],
    "parents" : [ 10836990 ],
    "children" : [ ]
  }, {
    "dbId" : 10837110,
    "stId" : "R-DME-6804324",
    "displayName" : "CASP7(2-303) dimer [cytosol]",
    "schemaClass" : "Complex",
    "speciesId" : 56210,
    "diagramIds" : [ 37689 ],
    "parents" : [ ],
    "children" : [ 10837108 ]
  }, {
    "dbId" : 10836982,
    "stId" : "R-DME-57021-2",
    "displayName" : "Dcp-1 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 56210,
    "identifier" : "O02002",
    "standardIdentifier" : "uniprot:O02002",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Dcp-1" ],
    "parents" : [ 10836990 ],
    "children" : [ ]
  }, {
    "dbId" : 10837104,
    "stId" : "R-DME-57029-4",
    "displayName" : "Strica [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 56210,
    "identifier" : "Q7KHK9",
    "standardIdentifier" : "uniprot:Q7KHK9",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Strica" ],
    "parents" : [ 10837108 ],
    "children" : [ ]
  }, {
    "dbId" : 10911088,
    "stId" : "R-DME-5620971",
    "displayName" : "Pyroptosis",
    "schemaClass" : "Pathway",
    "speciesId" : 56210,
    "diagramIds" : [ 37736 ]
  }, {
    "dbId" : 10837106,
    "stId" : "R-DME-57029-5",
    "displayName" : "Decay [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 56210,
    "identifier" : "Q9VET9",
    "standardIdentifier" : "uniprot:Q9VET9",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Decay" ],
    "parents" : [ 10837108 ],
    "children" : [ ]
  }, {
    "dbId" : 10837116,
    "stId" : "R-DME-141641-3",
    "displayName" : "Damm [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 56210,
    "identifier" : "Q7KHI6",
    "standardIdentifier" : "uniprot:Q7KHI6",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Damm" ],
    "parents" : [ 10837122 ],
    "children" : [ ]
  }, {
    "dbId" : 10836988,
    "stId" : "R-DME-57021-5",
    "displayName" : "Decay [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 56210,
    "identifier" : "Q9VET9",
    "standardIdentifier" : "uniprot:Q9VET9",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Decay" ],
    "parents" : [ 10836990 ],
    "children" : [ ]
  }, {
    "dbId" : 10837118,
    "stId" : "R-DME-141641-4",
    "displayName" : "Strica [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 56210,
    "identifier" : "Q7KHK9",
    "standardIdentifier" : "uniprot:Q7KHK9",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Strica" ],
    "parents" : [ 10837122 ],
    "children" : [ ]
  }, {
    "dbId" : 10836990,
    "stId" : "R-DME-57021-6",
    "displayName" : "Homologues of CASP3(1-277) [cytosol]",
    "schemaClass" : "DefinedSet",
    "speciesId" : 56210,
    "parents" : [ 10836992 ],
    "children" : [ 10836986, 10836984, 10836988, 10836982, 10836980 ]
  }, {
    "dbId" : 10837112,
    "stId" : "R-DME-141641",
    "displayName" : "Drice [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 56210,
    "identifier" : "O01382",
    "standardIdentifier" : "uniprot:O01382",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Drice" ],
    "parents" : [ 10837122 ],
    "children" : [ ]
  }, {
    "dbId" : 10836984,
    "stId" : "R-DME-57021-3",
    "displayName" : "Damm [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 56210,
    "identifier" : "Q7KHI6",
    "standardIdentifier" : "uniprot:Q7KHI6",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Damm" ],
    "parents" : [ 10836990 ],
    "children" : [ ]
  }, {
    "dbId" : 10837114,
    "stId" : "R-DME-141641-2",
    "displayName" : "Dcp-1 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 56210,
    "identifier" : "O02002",
    "standardIdentifier" : "uniprot:O02002",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Dcp-1" ],
    "parents" : [ 10837122 ],
    "children" : [ ]
  }, {
    "dbId" : 10836986,
    "stId" : "R-DME-57021-4",
    "displayName" : "Strica [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 56210,
    "identifier" : "Q7KHK9",
    "standardIdentifier" : "uniprot:Q7KHK9",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Strica" ],
    "parents" : [ 10836990 ],
    "children" : [ ]
  }, {
    "dbId" : 10837060,
    "stId" : "R-DME-50849-3",
    "displayName" : "Homologues of XIAP [cytosol]",
    "schemaClass" : "DefinedSet",
    "speciesId" : 56210,
    "diagramIds" : [ 37687 ],
    "parents" : [ 10903273, 10903254, 10837150, 10903265 ],
    "children" : [ 10837054, 10837058 ]
  }, {
    "dbId" : 10837058,
    "stId" : "R-DME-50849-2",
    "displayName" : "XIAP [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 56210,
    "identifier" : "Q24307",
    "standardIdentifier" : "uniprot:Q24307",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Diap2", "DIHA", "Iap2", "Ilp", "CG8293" ],
    "parents" : [ 10837060 ],
    "children" : [ ]
  }, {
    "dbId" : 10837069,
    "stId" : "R-DME-6804555",
    "displayName" : "APAF1:ATP:CYCS [cytosol]",
    "schemaClass" : "Complex",
    "speciesId" : 56210,
    "diagramIds" : [ 37671 ],
    "parents" : [ 10903261, 10837075 ],
    "children" : [ 10837067, 10837037 ]
  }, {
    "dbId" : 10837065,
    "stId" : "R-DME-9627055",
    "displayName" : "APAF1:ADP [cytosol]",
    "schemaClass" : "Complex",
    "speciesId" : 56210,
    "diagramIds" : [ 37670 ],
    "parents" : [ 10891723 ],
    "children" : [ 29370, 10837025 ]
  }, {
    "dbId" : 10891723,
    "stId" : "R-DME-6805523",
    "displayName" : "APAF1:AVEN [cytosol]",
    "schemaClass" : "Complex",
    "speciesId" : 56210,
    "diagramIds" : [ 37703 ],
    "parents" : [ ],
    "children" : [ 10837065, 10837085 ]
  }, {
    "dbId" : 10837067,
    "stId" : "R-DME-6804569",
    "displayName" : "APAF1:ATP [cytosol]",
    "schemaClass" : "Complex",
    "speciesId" : 56210,
    "parents" : [ 10837069 ],
    "children" : [ 113592, 10837025 ]
  }, {
    "dbId" : 10903254,
    "stId" : "R-DME-9627066",
    "displayName" : "XIAP:apoptosome [cytosol]",
    "schemaClass" : "Complex",
    "speciesId" : 56210,
    "diagramIds" : [ 37698 ],
    "parents" : [ ],
    "children" : [ 10837049, 10837060 ]
  }, {
    "dbId" : 10837073,
    "stId" : "R-DME-57033",
    "displayName" : "Dredd [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 56210,
    "diagramIds" : [ 37674 ],
    "identifier" : "Q8IRY7",
    "standardIdentifier" : "uniprot:Q8IRY7",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Dredd", "DCP2", "CG7486" ],
    "parents" : [ 10837075, 10837091 ],
    "children" : [ ]
  }, {
    "dbId" : 10837075,
    "stId" : "R-DME-6804619",
    "displayName" : "APAF1:ATP:CYCS heptamer:CASP9 [cytosol]",
    "schemaClass" : "Complex",
    "speciesId" : 56210,
    "diagramIds" : [ 37675 ],
    "parents" : [ 10891608 ],
    "children" : [ 10837069, 10837073 ]
  }, {
    "dbId" : 10911582,
    "stId" : "R-DME-1257604",
    "displayName" : "PIP3 activates AKT signaling",
    "schemaClass" : "Pathway",
    "speciesId" : 56210,
    "diagramIds" : [ 37724 ]
  }, {
    "dbId" : 10837085,
    "stId" : "R-DME-6805514",
    "displayName" : "Aven [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 56210,
    "diagramIds" : [ 37677 ],
    "identifier" : "Q9VYK8",
    "standardIdentifier" : "uniprot:Q9VYK8",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Aven" ],
    "parents" : [ 10891723 ],
    "children" : [ ]
  }, {
    "dbId" : 10903261,
    "stId" : "R-DME-9628212",
    "displayName" : "APAF1:ATP:CYCS heptamer:p-T412-CASP9 [cytosol]",
    "schemaClass" : "Complex",
    "speciesId" : 56210,
    "diagramIds" : [ 37706 ],
    "parents" : [ ],
    "children" : [ 10903259, 10837069 ]
  }, {
    "dbId" : 10837080,
    "stId" : "R-DME-1237171",
    "displayName" : "APIP [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 56210,
    "diagramIds" : [ 37676 ],
    "identifier" : "Q9VY93",
    "standardIdentifier" : "uniprot:Q9VY93",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 10891608 ],
    "children" : [ ]
  }, {
    "dbId" : 10903259,
    "stId" : "R-DME-9627087",
    "displayName" : "phospho-Dredd [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 56210,
    "identifier" : "Q8IRY7",
    "standardIdentifier" : "uniprot:Q8IRY7",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Dredd", "DCP2", "CG7486" ],
    "parents" : [ 10903261 ],
    "children" : [ ]
  }, {
    "dbId" : 10891608,
    "stId" : "R-DME-6804605",
    "displayName" : "APAF1:CYCS:ATP:APIP [cytosol]",
    "schemaClass" : "Complex",
    "speciesId" : 56210,
    "diagramIds" : [ 37701 ],
    "parents" : [ ],
    "children" : [ 10837080, 10837075 ]
  } ],
  "edges" : [ {
    "dbId" : 10837062,
    "stId" : "R-DME-114252",
    "displayName" : "Cleavage of Procaspase-3 by the apoptosome",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "preceding" : [ 10837096 ],
    "following" : [ 10903267 ],
    "inputs" : [ 113592, 10836992 ],
    "outputs" : [ 29370, 10837020 ],
    "catalysts" : [ 10837049 ],
    "efs" : [ ],
    "inhibitors" : [ 10837060 ],
    "diagramIds" : [ 37682 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10903269,
    "stId" : "R-DME-9627107",
    "displayName" : "XIAP binds CASP7",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "preceding" : [ 10837140 ],
    "inputs" : [ 10837138, 10837060 ],
    "outputs" : [ 10837150 ],
    "efs" : [ ],
    "diagramIds" : [ 37695 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10903267,
    "stId" : "R-DME-9627104",
    "displayName" : "XIAP binds CASP3",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "preceding" : [ 10837062 ],
    "inputs" : [ 10837020, 10837060 ],
    "outputs" : [ 10903265 ],
    "efs" : [ ],
    "diagramIds" : [ 37693 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10891841,
    "stId" : "R-DME-6805811",
    "displayName" : "Release of SEPT4 from mitochondria",
    "schemaClass" : "BlackBoxEvent",
    "speciesId" : 0,
    "following" : [ 10903275 ],
    "inputs" : [ 10891837 ],
    "outputs" : [ 10891839 ],
    "efs" : [ ],
    "diagramIds" : [ 37709 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10837071,
    "stId" : "R-DME-114254",
    "displayName" : "CYCS binds to APAF1",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "preceding" : [ 10837148 ],
    "following" : [ 10837087 ],
    "inputs" : [ 10837065, 113592, 10837037 ],
    "outputs" : [ 29370, 10837069 ],
    "efs" : [ ],
    "diagramIds" : [ 37668 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10891725,
    "stId" : "R-DME-6805507",
    "displayName" : "APAF1 binds AVEN",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "inputs" : [ 10837065, 10837085 ],
    "outputs" : [ 10891723 ],
    "efs" : [ ],
    "diagramIds" : [ 37702 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10837096,
    "stId" : "R-DME-114259",
    "displayName" : "Cleavage of Procaspase‑9 to caspase‑9",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "preceding" : [ 10903252 ],
    "following" : [ 10903256, 10837140, 10837062 ],
    "inputs" : [ 10837093 ],
    "outputs" : [ 10837049, 29370 ],
    "catalysts" : [ 10837093 ],
    "efs" : [ ],
    "diagramIds" : [ 37678 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10903275,
    "stId" : "R-DME-9627369",
    "displayName" : "SEPT4 binds XIAP",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "preceding" : [ 10891841 ],
    "inputs" : [ 10903271, 10837060 ],
    "outputs" : [ 10903273 ],
    "efs" : [ ],
    "diagramIds" : [ 37712 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10837140,
    "stId" : "R-DME-114261",
    "displayName" : "Cleavage of Procaspase-7 by the apoptosome",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "preceding" : [ 10837096 ],
    "following" : [ 10903269 ],
    "inputs" : [ 113592, 10837110 ],
    "outputs" : [ 29370, 10837138 ],
    "catalysts" : [ 10837049 ],
    "efs" : [ ],
    "inhibitors" : [ 10837060 ],
    "diagramIds" : [ 37688 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10903252,
    "stId" : "R-DME-9627056",
    "displayName" : "Procaspase 9 forms dimer",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "preceding" : [ 10837087 ],
    "following" : [ 10837096 ],
    "inputs" : [ 10837075 ],
    "outputs" : [ 10837093 ],
    "efs" : [ ],
    "diagramIds" : [ 37699 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10903263,
    "stId" : "R-DME-9627089",
    "displayName" : "CASP9 is phosphorylated at T412",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "inputs" : [ 113592, 10837075 ],
    "outputs" : [ 10903261, 29370 ],
    "catalysts" : [ 10840104 ],
    "efs" : [ ],
    "diagramIds" : [ 37704 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10837148,
    "stId" : "R-DME-114284",
    "displayName" : "Release of Cytochrome c from mitochondria",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "following" : [ 10837071 ],
    "inputs" : [ 10837146 ],
    "outputs" : [ 10837037 ],
    "efs" : [ ],
    "diagramIds" : [ 37665 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10837087,
    "stId" : "R-DME-114256",
    "displayName" : "CYCS:APAF1 binds procaspase-9",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "preceding" : [ 10837071 ],
    "following" : [ 10891610, 10903252 ],
    "inputs" : [ 10837069, 10837073 ],
    "outputs" : [ 10837075 ],
    "efs" : [ ],
    "inhibitors" : [ 10837080, 10837085 ],
    "diagramIds" : [ 37673 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10891610,
    "stId" : "R-DME-6804596",
    "displayName" : "APAF1:CYCS binds APIP",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "preceding" : [ 10837087 ],
    "inputs" : [ 10837080, 10837075 ],
    "outputs" : [ 10891608 ],
    "efs" : [ ],
    "diagramIds" : [ 37700 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10903256,
    "stId" : "R-DME-9627078",
    "displayName" : "XIAP binds CASP9",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "preceding" : [ 10837096 ],
    "inputs" : [ 10837049, 10837060 ],
    "outputs" : [ 10903254 ],
    "efs" : [ ],
    "diagramIds" : [ 37697 ],
    "entityFunctionalStatus" : [ ]
  } ],
  "subpathways" : [ {
    "dbId" : 10911084,
    "stId" : "R-DME-111458",
    "displayName" : "Formation of apoptosome",
    "events" : [ 10903252, 10837071, 10837087, 10903263, 10891725, 10891610, 10903256, 10837096 ]
  }, {
    "dbId" : 10911086,
    "stId" : "R-DME-111457",
    "displayName" : "Release of apoptotic factors from the mitochondria",
    "events" : [ 10891841, 10837148 ]
  }, {
    "dbId" : 10913276,
    "stId" : "R-DME-111469",
    "displayName" : "SMAC, XIAP-regulated apoptotic response",
    "events" : [ 10903269, 10903267, 10903275 ]
  }, {
    "dbId" : 10911072,
    "stId" : "R-DME-111459",
    "displayName" : "Activation of caspases through apoptosome-mediated cleavage",
    "events" : [ 10837140, 10837062 ]
  }, {
    "dbId" : 10912988,
    "stId" : "R-DME-9627069",
    "displayName" : "Regulation of the apoptosome activity",
    "events" : [ 10903263, 10891725, 10891610, 10903256 ]
  }, {
    "dbId" : 10911074,
    "stId" : "R-DME-111461",
    "displayName" : "Cytochrome c-mediated apoptotic response",
    "events" : [ 10837140, 10837062, 10903252, 10837071, 10837087, 10903263, 10891725, 10891610, 10903256, 10837096 ]
  }, {
    "dbId" : 10911076,
    "stId" : "R-DME-111471",
    "displayName" : "Apoptotic factor-mediated response",
    "events" : [ 10837140, 10837062, 10903252, 10837071, 10837087, 10903263, 10891725, 10891610, 10903256, 10837096, 10891841, 10837148, 10903269, 10903267, 10903275 ]
  } ]
}