{
  "dbId" : 10910880,
  "stableId" : "R-DME-72086",
  "displayName" : "mRNA Capping",
  "nodes" : [ {
    "id" : 117696,
    "reactomeId" : 10831952,
    "displayName" : "Cbp80",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 747,
      "y" : 630
    },
    "minX" : 722,
    "maxX" : 796,
    "minY" : 613,
    "maxY" : 661,
    "prop" : {
      "x" : 722,
      "y" : 619,
      "width" : 50,
      "height" : 22
    },
    "textPosition" : {
      "x" : 723,
      "y" : 619
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 772,
          "y" : 619
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 772,
          "y" : 619
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 117694,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 764,
          "y" : 644
        },
        "to" : {
          "x" : 796,
          "y" : 661
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 117699,
    "reactomeId" : 10835169,
    "displayName" : "RNMT",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 475,
      "y" : 497
    },
    "minX" : 417,
    "maxX" : 539,
    "minY" : 306,
    "maxY" : 515,
    "prop" : {
      "x" : 417,
      "y" : 479,
      "width" : 116,
      "height" : 36
    },
    "textPosition" : {
      "x" : 454,
      "y" : 486
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 533,
          "y" : 479
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 533,
          "y" : 479
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 117697,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 479,
          "y" : 476
        },
        "to" : {
          "x" : 522,
          "y" : 306
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 117698,
    "reactomeId" : 10835153,
    "displayName" : "RNA Pol II with phosphorylated CTD: CE complex",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 666,
      "y" : 492
    },
    "minX" : 522,
    "maxX" : 730,
    "minY" : 306,
    "maxY" : 524,
    "prop" : {
      "x" : 608,
      "y" : 460,
      "width" : 116,
      "height" : 64
    },
    "textPosition" : {
      "x" : 610,
      "y" : 475
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 724,
          "y" : 460
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 724,
          "y" : 460
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 117697,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 641,
          "y" : 457
        },
        "to" : {
          "x" : 522,
          "y" : 306
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 117700,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 117701,
    "reactomeId" : 10835153,
    "displayName" : "RNA Pol II with phosphorylated CTD: CE complex",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 853,
      "y" : 492
    },
    "minX" : 797,
    "maxX" : 915,
    "minY" : 461,
    "maxY" : 517,
    "prop" : {
      "x" : 797,
      "y" : 467,
      "width" : 112,
      "height" : 50
    },
    "textPosition" : {
      "x" : 797,
      "y" : 468
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 909,
          "y" : 467
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 909,
          "y" : 467
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 117700,
      "type" : "INPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 117702,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 117703,
    "reactomeId" : 10835151,
    "displayName" : "RNGTT",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 1046,
      "y" : 542
    },
    "minX" : 987,
    "maxX" : 1101,
    "minY" : 506,
    "maxY" : 560,
    "prop" : {
      "x" : 997,
      "y" : 524,
      "width" : 98,
      "height" : 36
    },
    "textPosition" : {
      "x" : 1022,
      "y" : 531
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1095,
          "y" : 524
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1095,
          "y" : 524
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 117702,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1016,
          "y" : 521
        },
        "to" : {
          "x" : 987,
          "y" : 506
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 117704,
    "reactomeId" : 10835157,
    "displayName" : "Pol II transcription complex with (ser5) phosphorylated CTD containing extruded transcript to +30",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 1083,
      "y" : 424
    },
    "minX" : 987,
    "maxX" : 1157,
    "minY" : 372,
    "maxY" : 506,
    "prop" : {
      "x" : 1016,
      "y" : 378,
      "width" : 135,
      "height" : 92
    },
    "textPosition" : {
      "x" : 1015,
      "y" : 393
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1151,
          "y" : 378
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1151,
          "y" : 378
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 117702,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1029,
          "y" : 473
        },
        "to" : {
          "x" : 987,
          "y" : 506
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 117669,
    "reactomeId" : 29428,
    "displayName" : "DNA",
    "schemaClass" : "OtherEntity",
    "renderableClass" : "Entity",
    "position" : {
      "x" : 132,
      "y" : 170
    },
    "minX" : 115,
    "maxX" : 166,
    "minY" : 159,
    "maxY" : 205,
    "prop" : {
      "x" : 115,
      "y" : 159,
      "width" : 34,
      "height" : 22
    },
    "textPosition" : {
      "x" : 115,
      "y" : 159
    },
    "connectors" : [ {
      "edgeId" : 117668,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 142,
          "y" : 184
        },
        "to" : {
          "x" : 166,
          "y" : 205
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 117671,
    "reactomeId" : 10835177,
    "displayName" : "CE:Pol II CTD:Spt5 complex",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 289,
      "y" : 137
    },
    "minX" : 166,
    "maxX" : 354,
    "minY" : 113,
    "maxY" : 205,
    "prop" : {
      "x" : 231,
      "y" : 119,
      "width" : 117,
      "height" : 36
    },
    "textPosition" : {
      "x" : 243,
      "y" : 120
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 348,
          "y" : 119
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 348,
          "y" : 119
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 117697,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 117668,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 256,
          "y" : 158
        },
        "to" : {
          "x" : 166,
          "y" : 205
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 117670,
    "reactomeId" : 72084,
    "displayName" : "nascent pre-mRNA transcript",
    "schemaClass" : "OtherEntity",
    "renderableClass" : "Entity",
    "position" : {
      "x" : 179,
      "y" : 260
    },
    "minX" : 118,
    "maxX" : 241,
    "minY" : 205,
    "maxY" : 278,
    "prop" : {
      "x" : 118,
      "y" : 242,
      "width" : 123,
      "height" : 36
    },
    "textPosition" : {
      "x" : 125,
      "y" : 242
    },
    "connectors" : [ {
      "edgeId" : 117668,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 174,
          "y" : 239
        },
        "to" : {
          "x" : 166,
          "y" : 205
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 117672,
    "reactomeId" : 10835181,
    "displayName" : "Capping complex (initial)",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 337,
      "y" : 207
    },
    "minX" : 281,
    "maxX" : 400,
    "minY" : 183,
    "maxY" : 293,
    "prop" : {
      "x" : 281,
      "y" : 189,
      "width" : 113,
      "height" : 36
    },
    "textPosition" : {
      "x" : 284,
      "y" : 190
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 394,
          "y" : 189
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 394,
          "y" : 189
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 117668,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 117673,
      "type" : "INPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 117673,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 342,
          "y" : 228
        },
        "to" : {
          "x" : 361,
          "y" : 292
        }
      }, {
        "from" : {
          "x" : 361,
          "y" : 292
        },
        "to" : {
          "x" : 346,
          "y" : 290
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 342,
          "y" : 289
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 342,
          "y" : 289
        }
      }
    } ]
  }, {
    "id" : 117675,
    "reactomeId" : 10835185,
    "displayName" : "Capping complex (hydrolyzed)",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 399,
      "y" : 373
    },
    "minX" : 331,
    "maxX" : 465,
    "minY" : 326,
    "maxY" : 477,
    "prop" : {
      "x" : 340,
      "y" : 355,
      "width" : 119,
      "height" : 36
    },
    "textPosition" : {
      "x" : 340,
      "y" : 356
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 459,
          "y" : 355
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 459,
          "y" : 355
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 117673,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 372,
          "y" : 352
        },
        "to" : {
          "x" : 331,
          "y" : 326
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 364,
          "y" : 352
        },
        "b" : {
          "x" : 372,
          "y" : 352
        },
        "c" : {
          "x" : 368,
          "y" : 345
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 368,
          "y" : 345
        }
      }
    }, {
      "edgeId" : 117676,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 384,
          "y" : 394
        },
        "to" : {
          "x" : 356,
          "y" : 428
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 117676,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 398,
          "y" : 394
        },
        "to" : {
          "x" : 398,
          "y" : 474
        }
      }, {
        "from" : {
          "x" : 398,
          "y" : 474
        },
        "to" : {
          "x" : 372,
          "y" : 473
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 368,
          "y" : 473
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 368,
          "y" : 473
        }
      }
    } ]
  }, {
    "id" : 117674,
    "reactomeId" : 113550,
    "displayName" : "Pi",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 248,
      "y" : 350
    },
    "minX" : 194,
    "maxX" : 331,
    "minY" : 326,
    "maxY" : 365,
    "prop" : {
      "x" : 194,
      "y" : 335,
      "width" : 109,
      "height" : 30
    },
    "textPosition" : {
      "x" : 239,
      "y" : 339
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 298,
          "y" : 340
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 298,
          "y" : 340
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 117673,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 299,
          "y" : 332
        },
        "to" : {
          "x" : 331,
          "y" : 326
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 305,
          "y" : 327
        },
        "b" : {
          "x" : 299,
          "y" : 332
        },
        "c" : {
          "x" : 307,
          "y" : 335
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 307,
          "y" : 335
        }
      }
    } ]
  }, {
    "id" : 117677,
    "reactomeId" : 113571,
    "displayName" : "GTP",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 302,
      "y" : 406
    },
    "minX" : 282,
    "maxX" : 356,
    "minY" : 390,
    "maxY" : 428,
    "prop" : {
      "x" : 282,
      "y" : 391,
      "width" : 40,
      "height" : 30
    },
    "textPosition" : {
      "x" : 286,
      "y" : 395
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 317,
          "y" : 396
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 317,
          "y" : 396
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 117676,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 325,
          "y" : 414
        },
        "to" : {
          "x" : 356,
          "y" : 428
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 117679,
    "reactomeId" : 10835192,
    "displayName" : "Capping complex  (intermediate)",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 283,
      "y" : 582
    },
    "minX" : 225,
    "maxX" : 356,
    "minY" : 524,
    "maxY" : 660,
    "prop" : {
      "x" : 225,
      "y" : 564,
      "width" : 117,
      "height" : 36
    },
    "textPosition" : {
      "x" : 223,
      "y" : 565
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 342,
          "y" : 564
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 342,
          "y" : 564
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 117680,
      "type" : "INPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 117680,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 274,
          "y" : 603
        },
        "to" : {
          "x" : 248,
          "y" : 657
        }
      }, {
        "from" : {
          "x" : 248,
          "y" : 657
        },
        "to" : {
          "x" : 265,
          "y" : 656
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 269,
          "y" : 656
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 269,
          "y" : 656
        }
      }
    }, {
      "edgeId" : 117676,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 305,
          "y" : 561
        },
        "to" : {
          "x" : 356,
          "y" : 524
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 308,
          "y" : 554
        },
        "b" : {
          "x" : 305,
          "y" : 561
        },
        "c" : {
          "x" : 313,
          "y" : 560
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 313,
          "y" : 560
        }
      }
    } ]
  }, {
    "id" : 117678,
    "reactomeId" : 111349,
    "displayName" : "GDP",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 410,
      "y" : 584
    },
    "minX" : 356,
    "maxX" : 432,
    "minY" : 524,
    "maxY" : 599,
    "prop" : {
      "x" : 390,
      "y" : 569,
      "width" : 41,
      "height" : 30
    },
    "textPosition" : {
      "x" : 393,
      "y" : 573
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 426,
          "y" : 574
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 426,
          "y" : 574
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 117676,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 396,
          "y" : 566
        },
        "to" : {
          "x" : 356,
          "y" : 524
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 388,
          "y" : 564
        },
        "b" : {
          "x" : 396,
          "y" : 566
        },
        "c" : {
          "x" : 394,
          "y" : 558
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 394,
          "y" : 558
        }
      }
    } ],
    "trivial" : true
  }, {
    "id" : 117681,
    "reactomeId" : 10835197,
    "displayName" : "Capping complex (GpppN..)",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 281,
      "y" : 730
    },
    "minX" : 222,
    "maxX" : 347,
    "minY" : 706,
    "maxY" : 748,
    "prop" : {
      "x" : 222,
      "y" : 712,
      "width" : 119,
      "height" : 36
    },
    "textPosition" : {
      "x" : 222,
      "y" : 713
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 341,
          "y" : 712
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 341,
          "y" : 712
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 117680,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 117682,
      "type" : "INPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 117683,
    "reactomeId" : 10835202,
    "displayName" : "Capping complex (with freed 5'- GMP)",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 284,
      "y" : 869
    },
    "minX" : 219,
    "maxX" : 481,
    "minY" : 845,
    "maxY" : 905,
    "prop" : {
      "x" : 219,
      "y" : 851,
      "width" : 131,
      "height" : 36
    },
    "textPosition" : {
      "x" : 219,
      "y" : 852
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 350,
          "y" : 851
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 350,
          "y" : 851
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 117682,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 117684,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 353,
          "y" : 868
        },
        "to" : {
          "x" : 430,
          "y" : 868
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 117684,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 353,
          "y" : 881
        },
        "to" : {
          "x" : 476,
          "y" : 905
        }
      }, {
        "from" : {
          "x" : 476,
          "y" : 905
        },
        "to" : {
          "x" : 477,
          "y" : 885
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 477,
          "y" : 881
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 477,
          "y" : 881
        }
      }
    } ]
  }, {
    "id" : 117685,
    "reactomeId" : 77087,
    "displayName" : "AdoMet",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 380,
      "y" : 804
    },
    "minX" : 315,
    "maxX" : 446,
    "minY" : 781,
    "maxY" : 868,
    "prop" : {
      "x" : 315,
      "y" : 782,
      "width" : 130,
      "height" : 44
    },
    "textPosition" : {
      "x" : 352,
      "y" : 793
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 440,
          "y" : 787
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 440,
          "y" : 787
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 117684,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 397,
          "y" : 829
        },
        "to" : {
          "x" : 430,
          "y" : 868
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 117687,
    "reactomeId" : 10835175,
    "displayName" : "phospho-Spt5",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 582,
      "y" : 644
    },
    "minX" : 522,
    "maxX" : 623,
    "minY" : 306,
    "maxY" : 869,
    "prop" : {
      "x" : 547,
      "y" : 633,
      "width" : 70,
      "height" : 22
    },
    "textPosition" : {
      "x" : 548,
      "y" : 627
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 617,
          "y" : 633
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 617,
          "y" : 633
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 117697,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 580,
          "y" : 630
        },
        "to" : {
          "x" : 522,
          "y" : 306
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 117684,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 582,
          "y" : 658
        },
        "to" : {
          "x" : 594,
          "y" : 869
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 586,
          "y" : 665
        },
        "b" : {
          "x" : 582,
          "y" : 658
        },
        "c" : {
          "x" : 578,
          "y" : 665
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 578,
          "y" : 665
        }
      }
    } ]
  }, {
    "id" : 117686,
    "reactomeId" : 10833180,
    "displayName" : "TFIIH",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 557,
      "y" : 923
    },
    "minX" : 539,
    "maxX" : 594,
    "minY" : 869,
    "maxY" : 934,
    "prop" : {
      "x" : 539,
      "y" : 912,
      "width" : 37,
      "height" : 22
    },
    "textPosition" : {
      "x" : 539,
      "y" : 913
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 576,
          "y" : 912
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 576,
          "y" : 912
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 117684,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 564,
          "y" : 909
        },
        "to" : {
          "x" : 594,
          "y" : 869
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 565,
          "y" : 901
        },
        "b" : {
          "x" : 564,
          "y" : 909
        },
        "c" : {
          "x" : 571,
          "y" : 906
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 571,
          "y" : 906
        }
      }
    } ]
  }, {
    "id" : 117689,
    "reactomeId" : 77502,
    "displayName" : "AdoHcy",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 682,
      "y" : 935
    },
    "minX" : 594,
    "maxX" : 752,
    "minY" : 869,
    "maxY" : 964,
    "prop" : {
      "x" : 613,
      "y" : 906,
      "width" : 138,
      "height" : 58
    },
    "textPosition" : {
      "x" : 655,
      "y" : 924
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 746,
          "y" : 911
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 746,
          "y" : 911
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 117684,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 643,
          "y" : 903
        },
        "to" : {
          "x" : 594,
          "y" : 869
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 635,
          "y" : 902
        },
        "b" : {
          "x" : 643,
          "y" : 903
        },
        "c" : {
          "x" : 640,
          "y" : 896
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 640,
          "y" : 896
        }
      }
    } ]
  }, {
    "id" : 117688,
    "reactomeId" : 10832045,
    "displayName" : "RNA Polymerase II (phosphorylated):TFIIF:capped pre-mRNA",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 772,
      "y" : 869
    },
    "minX" : 594,
    "maxX" : 861,
    "minY" : 797,
    "maxY" : 901,
    "prop" : {
      "x" : 710,
      "y" : 837,
      "width" : 124,
      "height" : 64
    },
    "textPosition" : {
      "x" : 710,
      "y" : 838
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 834,
          "y" : 837
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 834,
          "y" : 837
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 117684,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 707,
          "y" : 869
        },
        "to" : {
          "x" : 594,
          "y" : 869
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 700,
          "y" : 873
        },
        "b" : {
          "x" : 707,
          "y" : 869
        },
        "c" : {
          "x" : 700,
          "y" : 865
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 700,
          "y" : 865
        }
      }
    }, {
      "edgeId" : 117691,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 811,
          "y" : 834
        },
        "to" : {
          "x" : 861,
          "y" : 797
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 117690,
    "reactomeId" : 10835206,
    "displayName" : "mRNA capping factors",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 649,
      "y" : 824
    },
    "minX" : 594,
    "maxX" : 704,
    "minY" : 800,
    "maxY" : 869,
    "prop" : {
      "x" : 600,
      "y" : 806,
      "width" : 98,
      "height" : 36
    },
    "textPosition" : {
      "x" : 598,
      "y" : 807
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 698,
          "y" : 806
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 698,
          "y" : 806
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 117684,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 627,
          "y" : 845
        },
        "to" : {
          "x" : 594,
          "y" : 869
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 624,
          "y" : 852
        },
        "b" : {
          "x" : 627,
          "y" : 845
        },
        "c" : {
          "x" : 619,
          "y" : 846
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 619,
          "y" : 846
        }
      }
    } ]
  }, {
    "id" : 117693,
    "reactomeId" : 10832047,
    "displayName" : "capped pre-mRNA:CBC:RNA Pol II (phosphorylated) complex",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 1010,
      "y" : 798
    },
    "minX" : 948,
    "maxX" : 1079,
    "minY" : 760,
    "maxY" : 830,
    "prop" : {
      "x" : 948,
      "y" : 766,
      "width" : 125,
      "height" : 64
    },
    "textPosition" : {
      "x" : 948,
      "y" : 767
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1073,
          "y" : 766
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1073,
          "y" : 766
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 117691,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 117692,
    "reactomeId" : 10831954,
    "displayName" : "Cap Binding Complex (CBC)",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 790,
      "y" : 729
    },
    "minX" : 741,
    "maxX" : 861,
    "minY" : 705,
    "maxY" : 797,
    "prop" : {
      "x" : 741,
      "y" : 711,
      "width" : 99,
      "height" : 36
    },
    "textPosition" : {
      "x" : 741,
      "y" : 712
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 840,
          "y" : 711
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 840,
          "y" : 711
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 117691,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 808,
          "y" : 750
        },
        "to" : {
          "x" : 861,
          "y" : 797
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 117694,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 117695,
    "reactomeId" : 10831947,
    "displayName" : "NCBP2",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 823,
      "y" : 630
    },
    "minX" : 796,
    "maxX" : 854,
    "minY" : 613,
    "maxY" : 661,
    "prop" : {
      "x" : 798,
      "y" : 619,
      "width" : 50,
      "height" : 22
    },
    "textPosition" : {
      "x" : 798,
      "y" : 619
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 848,
          "y" : 619
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 848,
          "y" : 619
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 117694,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 813,
          "y" : 644
        },
        "to" : {
          "x" : 796,
          "y" : 661
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  } ],
  "edges" : [ {
    "id" : 117697,
    "reactomeId" : 10835179,
    "displayName" : "SPT5 subunit of Pol II binds the RNA triphosphatase (RTP)",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 559,
      "y" : 136
    },
    "minX" : 351,
    "maxX" : 565,
    "minY" : 130,
    "maxY" : 306,
    "reactionType" : "binding",
    "segments" : [ {
      "from" : {
        "x" : 522,
        "y" : 306
      },
      "to" : {
        "x" : 559,
        "y" : 136
      }
    }, {
      "from" : {
        "x" : 559,
        "y" : 136
      },
      "to" : {
        "x" : 351,
        "y" : 136
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 358,
        "y" : 132
      },
      "b" : {
        "x" : 351,
        "y" : 136
      },
      "c" : {
        "x" : 358,
        "y" : 140
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 358,
        "y" : 140
      }
    },
    "reactionShape" : {
      "c" : {
        "x" : 559,
        "y" : 136
      },
      "r" : 5,
      "type" : "CIRCLE",
      "centre" : {
        "x" : 559,
        "y" : 136
      }
    },
    "inputs" : [ {
      "id" : 117698,
      "points" : [ {
        "x" : 641,
        "y" : 457
      } ]
    }, {
      "id" : 117699,
      "points" : [ {
        "x" : 479,
        "y" : 476
      } ]
    }, {
      "id" : 117687,
      "points" : [ {
        "x" : 580,
        "y" : 630
      } ]
    } ],
    "outputs" : [ {
      "id" : 117671
    } ]
  }, {
    "id" : 117680,
    "reactomeId" : 10835200,
    "displayName" : "Transfer of GMP from the capping enzyme GT site to 5'-end of mRNA",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 281,
      "y" : 656
    },
    "minX" : 275,
    "maxX" : 287,
    "minY" : 603,
    "maxY" : 709,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 282,
        "y" : 603
      },
      "to" : {
        "x" : 281,
        "y" : 656
      }
    }, {
      "from" : {
        "x" : 281,
        "y" : 656
      },
      "to" : {
        "x" : 281,
        "y" : 709
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 277,
        "y" : 702
      },
      "b" : {
        "x" : 281,
        "y" : 709
      },
      "c" : {
        "x" : 285,
        "y" : 702
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 285,
        "y" : 702
      }
    },
    "reactionShape" : {
      "a" : {
        "x" : 275,
        "y" : 650
      },
      "b" : {
        "x" : 287,
        "y" : 662
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 281,
        "y" : 656
      }
    },
    "inputs" : [ {
      "id" : 117679
    } ],
    "outputs" : [ {
      "id" : 117681
    } ],
    "catalysts" : [ {
      "id" : 117679,
      "points" : [ {
        "x" : 274,
        "y" : 603
      }, {
        "x" : 248,
        "y" : 657
      } ]
    } ]
  }, {
    "id" : 117682,
    "reactomeId" : 10835204,
    "displayName" : "Dissociation of  transcript with 5'-GMP from GT",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 280,
      "y" : 801
    },
    "minX" : 274,
    "maxX" : 286,
    "minY" : 751,
    "maxY" : 848,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 280,
        "y" : 751
      },
      "to" : {
        "x" : 280,
        "y" : 801
      }
    }, {
      "from" : {
        "x" : 280,
        "y" : 801
      },
      "to" : {
        "x" : 282,
        "y" : 848
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 278,
        "y" : 841
      },
      "b" : {
        "x" : 282,
        "y" : 848
      },
      "c" : {
        "x" : 286,
        "y" : 841
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 286,
        "y" : 841
      }
    },
    "reactionShape" : {
      "a" : {
        "x" : 274,
        "y" : 795
      },
      "b" : {
        "x" : 286,
        "y" : 807
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 280,
        "y" : 801
      }
    },
    "inputs" : [ {
      "id" : 117681
    } ],
    "outputs" : [ {
      "id" : 117683
    } ]
  }, {
    "id" : 117700,
    "reactomeId" : 10835155,
    "displayName" : "Activation of GT",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 773,
      "y" : 492
    },
    "minX" : 727,
    "maxX" : 794,
    "minY" : 486,
    "maxY" : 498,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 794,
        "y" : 492
      },
      "to" : {
        "x" : 773,
        "y" : 492
      }
    }, {
      "from" : {
        "x" : 773,
        "y" : 492
      },
      "to" : {
        "x" : 727,
        "y" : 492
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 734,
        "y" : 488
      },
      "b" : {
        "x" : 727,
        "y" : 492
      },
      "c" : {
        "x" : 734,
        "y" : 496
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 734,
        "y" : 496
      }
    },
    "reactionShape" : {
      "a" : {
        "x" : 767,
        "y" : 486
      },
      "b" : {
        "x" : 779,
        "y" : 498
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 773,
        "y" : 492
      }
    },
    "inputs" : [ {
      "id" : 117701
    } ],
    "outputs" : [ {
      "id" : 117698
    } ]
  }, {
    "id" : 117668,
    "reactomeId" : 10835183,
    "displayName" : "Capping complex formation",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 232,
      "y" : 205
    },
    "minX" : 166,
    "maxX" : 278,
    "minY" : 199,
    "maxY" : 211,
    "reactionType" : "binding",
    "segments" : [ {
      "from" : {
        "x" : 166,
        "y" : 205
      },
      "to" : {
        "x" : 232,
        "y" : 205
      }
    }, {
      "from" : {
        "x" : 232,
        "y" : 205
      },
      "to" : {
        "x" : 278,
        "y" : 205
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 271,
        "y" : 209
      },
      "b" : {
        "x" : 278,
        "y" : 205
      },
      "c" : {
        "x" : 271,
        "y" : 201
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 271,
        "y" : 201
      }
    },
    "reactionShape" : {
      "c" : {
        "x" : 232,
        "y" : 205
      },
      "r" : 5,
      "type" : "CIRCLE",
      "centre" : {
        "x" : 232,
        "y" : 205
      }
    },
    "inputs" : [ {
      "id" : 117669,
      "points" : [ {
        "x" : 142,
        "y" : 184
      } ]
    }, {
      "id" : 117670,
      "points" : [ {
        "x" : 174,
        "y" : 239
      } ]
    }, {
      "id" : 117671,
      "points" : [ {
        "x" : 256,
        "y" : 158
      } ]
    } ],
    "outputs" : [ {
      "id" : 117672
    } ]
  }, {
    "id" : 117684,
    "reactomeId" : 10835209,
    "displayName" : "Methylation of GMP-cap by RNA Methyltransferase",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 477,
      "y" : 869
    },
    "minX" : 430,
    "maxX" : 594,
    "minY" : 863,
    "maxY" : 875,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 430,
        "y" : 868
      },
      "to" : {
        "x" : 477,
        "y" : 869
      }
    }, {
      "from" : {
        "x" : 477,
        "y" : 869
      },
      "to" : {
        "x" : 594,
        "y" : 869
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 471,
        "y" : 863
      },
      "b" : {
        "x" : 483,
        "y" : 875
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 477,
        "y" : 869
      }
    },
    "inputs" : [ {
      "id" : 117683,
      "points" : [ {
        "x" : 353,
        "y" : 868
      } ]
    }, {
      "id" : 117685,
      "points" : [ {
        "x" : 397,
        "y" : 829
      } ]
    } ],
    "outputs" : [ {
      "id" : 117686,
      "points" : [ {
        "x" : 564,
        "y" : 909
      } ]
    }, {
      "id" : 117687,
      "points" : [ {
        "x" : 582,
        "y" : 658
      } ]
    }, {
      "id" : 117688,
      "points" : [ {
        "x" : 707,
        "y" : 869
      } ]
    }, {
      "id" : 117689,
      "points" : [ {
        "x" : 643,
        "y" : 903
      } ]
    }, {
      "id" : 117690,
      "points" : [ {
        "x" : 627,
        "y" : 845
      } ]
    } ],
    "catalysts" : [ {
      "id" : 117683,
      "points" : [ {
        "x" : 353,
        "y" : 881
      }, {
        "x" : 476,
        "y" : 905
      } ]
    } ]
  }, {
    "id" : 117702,
    "reactomeId" : 10835159,
    "displayName" : "RNA Polymerase II CTD (phosphorylated) binds to CE",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 952,
      "y" : 494
    },
    "minX" : 912,
    "maxX" : 987,
    "minY" : 488,
    "maxY" : 506,
    "reactionType" : "binding",
    "segments" : [ {
      "from" : {
        "x" : 987,
        "y" : 506
      },
      "to" : {
        "x" : 952,
        "y" : 494
      }
    }, {
      "from" : {
        "x" : 952,
        "y" : 494
      },
      "to" : {
        "x" : 912,
        "y" : 493
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 919,
        "y" : 489
      },
      "b" : {
        "x" : 912,
        "y" : 493
      },
      "c" : {
        "x" : 919,
        "y" : 497
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 919,
        "y" : 497
      }
    },
    "reactionShape" : {
      "c" : {
        "x" : 952,
        "y" : 494
      },
      "r" : 5,
      "type" : "CIRCLE",
      "centre" : {
        "x" : 952,
        "y" : 494
      }
    },
    "inputs" : [ {
      "id" : 117703,
      "points" : [ {
        "x" : 1016,
        "y" : 521
      } ]
    }, {
      "id" : 117704,
      "points" : [ {
        "x" : 1029,
        "y" : 473
      } ]
    } ],
    "outputs" : [ {
      "id" : 117701
    } ]
  }, {
    "id" : 117673,
    "reactomeId" : 10835188,
    "displayName" : "Hydrolysis of the 5'-end of the nascent transcript by the capping enzyme",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 330,
      "y" : 287
    },
    "minX" : 324,
    "maxX" : 336,
    "minY" : 228,
    "maxY" : 326,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 335,
        "y" : 228
      },
      "to" : {
        "x" : 330,
        "y" : 287
      }
    }, {
      "from" : {
        "x" : 330,
        "y" : 287
      },
      "to" : {
        "x" : 331,
        "y" : 326
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 324,
        "y" : 281
      },
      "b" : {
        "x" : 336,
        "y" : 293
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 330,
        "y" : 287
      }
    },
    "inputs" : [ {
      "id" : 117672
    } ],
    "outputs" : [ {
      "id" : 117674,
      "points" : [ {
        "x" : 299,
        "y" : 332
      } ]
    }, {
      "id" : 117675,
      "points" : [ {
        "x" : 372,
        "y" : 352
      } ]
    } ],
    "catalysts" : [ {
      "id" : 117672,
      "points" : [ {
        "x" : 342,
        "y" : 228
      }, {
        "x" : 361,
        "y" : 292
      } ]
    } ]
  }, {
    "id" : 117691,
    "reactomeId" : 10835213,
    "displayName" : "Recognition and binding of the mRNA cap by the cap-binding complex",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 899,
      "y" : 796
    },
    "minX" : 861,
    "maxX" : 945,
    "minY" : 790,
    "maxY" : 802,
    "reactionType" : "binding",
    "segments" : [ {
      "from" : {
        "x" : 861,
        "y" : 797
      },
      "to" : {
        "x" : 899,
        "y" : 796
      }
    }, {
      "from" : {
        "x" : 899,
        "y" : 796
      },
      "to" : {
        "x" : 945,
        "y" : 796
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 938,
        "y" : 800
      },
      "b" : {
        "x" : 945,
        "y" : 796
      },
      "c" : {
        "x" : 938,
        "y" : 792
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 938,
        "y" : 792
      }
    },
    "reactionShape" : {
      "c" : {
        "x" : 899,
        "y" : 796
      },
      "r" : 5,
      "type" : "CIRCLE",
      "centre" : {
        "x" : 899,
        "y" : 796
      }
    },
    "inputs" : [ {
      "id" : 117688,
      "points" : [ {
        "x" : 811,
        "y" : 834
      } ]
    }, {
      "id" : 117692,
      "points" : [ {
        "x" : 808,
        "y" : 750
      } ]
    } ],
    "outputs" : [ {
      "id" : 117693
    } ]
  }, {
    "id" : 117676,
    "reactomeId" : 10835195,
    "displayName" : "Formation of the CE:GMP intermediate complex",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 356,
      "y" : 473
    },
    "minX" : 350,
    "maxX" : 362,
    "minY" : 428,
    "maxY" : 524,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 356,
        "y" : 428
      },
      "to" : {
        "x" : 356,
        "y" : 473
      }
    }, {
      "from" : {
        "x" : 356,
        "y" : 473
      },
      "to" : {
        "x" : 356,
        "y" : 524
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 350,
        "y" : 467
      },
      "b" : {
        "x" : 362,
        "y" : 479
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 356,
        "y" : 473
      }
    },
    "inputs" : [ {
      "id" : 117675,
      "points" : [ {
        "x" : 384,
        "y" : 394
      } ]
    }, {
      "id" : 117677,
      "points" : [ {
        "x" : 325,
        "y" : 414
      } ]
    } ],
    "outputs" : [ {
      "id" : 117678,
      "points" : [ {
        "x" : 396,
        "y" : 566
      } ]
    }, {
      "id" : 117679,
      "points" : [ {
        "x" : 305,
        "y" : 561
      } ]
    } ],
    "catalysts" : [ {
      "id" : 117675,
      "points" : [ {
        "x" : 398,
        "y" : 394
      }, {
        "x" : 398,
        "y" : 474
      } ]
    } ]
  }, {
    "id" : 117694,
    "reactomeId" : 10835211,
    "displayName" : "Formation of cap binding complex (CBC)",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 796,
      "y" : 680
    },
    "minX" : 790,
    "maxX" : 802,
    "minY" : 661,
    "maxY" : 708,
    "reactionType" : "binding",
    "segments" : [ {
      "from" : {
        "x" : 796,
        "y" : 661
      },
      "to" : {
        "x" : 796,
        "y" : 680
      }
    }, {
      "from" : {
        "x" : 796,
        "y" : 680
      },
      "to" : {
        "x" : 792,
        "y" : 708
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 789,
        "y" : 701
      },
      "b" : {
        "x" : 792,
        "y" : 708
      },
      "c" : {
        "x" : 797,
        "y" : 702
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 797,
        "y" : 702
      }
    },
    "reactionShape" : {
      "c" : {
        "x" : 796,
        "y" : 680
      },
      "r" : 5,
      "type" : "CIRCLE",
      "centre" : {
        "x" : 796,
        "y" : 680
      }
    },
    "inputs" : [ {
      "id" : 117695,
      "points" : [ {
        "x" : 813,
        "y" : 644
      } ]
    }, {
      "id" : 117696,
      "points" : [ {
        "x" : 764,
        "y" : 644
      } ]
    } ],
    "outputs" : [ {
      "id" : 117692
    } ]
  } ],
  "compartments" : [ {
    "id" : 117705,
    "reactomeId" : 70101,
    "displayName" : "cytosol",
    "schemaClass" : "Compartment",
    "renderableClass" : "Compartment",
    "position" : {
      "x" : 799,
      "y" : 550
    },
    "minX" : 0,
    "maxX" : 1598,
    "minY" : 0,
    "maxY" : 1100,
    "prop" : {
      "x" : 0,
      "y" : 0,
      "width" : 1598,
      "height" : 1100
    },
    "textPosition" : {
      "x" : 19,
      "y" : 1063
    },
    "insets" : {
      "x" : 10,
      "y" : 10,
      "width" : 1578,
      "height" : 1080
    },
    "bgColor" : {
      "r" : 250,
      "g" : 240,
      "b" : 240
    },
    "componentIds" : [ 117706 ]
  }, {
    "id" : 117706,
    "reactomeId" : 7660,
    "displayName" : "nucleoplasm",
    "schemaClass" : "Compartment",
    "renderableClass" : "Compartment",
    "position" : {
      "x" : 793,
      "y" : 544
    },
    "minX" : 38,
    "maxX" : 1548,
    "minY" : 34,
    "maxY" : 1054,
    "prop" : {
      "x" : 38,
      "y" : 34,
      "width" : 1510,
      "height" : 1020
    },
    "textPosition" : {
      "x" : 56,
      "y" : 1013
    },
    "insets" : {
      "x" : 48,
      "y" : 44,
      "width" : 1490,
      "height" : 1000
    },
    "bgColor" : {
      "r" : 250,
      "g" : 240,
      "b" : 240
    },
    "componentIds" : [ 117668, 117670, 117671, 117672, 117669, 117673, 117674, 117675, 117676, 117677, 117678, 117679, 117680, 117681, 117682, 117683, 117684, 117685, 117686, 117688, 117690, 117689, 117691, 117692, 117693, 117694, 117696, 117695, 117697, 117699, 117698, 117700, 117701, 117702, 117703, 117704, 117687 ]
  } ],
  "notes" : [ ],
  "links" : [ ],
  "shadows" : [ ],
  "minX" : 0,
  "maxX" : 1598,
  "minY" : 0,
  "maxY" : 1100,
  "disease" : false
}