{
  "dbId" : 10825773,
  "stableId" : "R-GGA-453274",
  "displayName" : "Mitotic G2-G2/M phases",
  "nodes" : [ {
    "id" : 138242,
    "reactomeId" : 29370,
    "displayName" : "ADP",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 613,
      "y" : 2168
    },
    "minX" : 594,
    "maxX" : 654,
    "minY" : 2119,
    "maxY" : 2181,
    "prop" : {
      "x" : 594,
      "y" : 2155,
      "width" : 39,
      "height" : 26
    },
    "textPosition" : {
      "x" : 597,
      "y" : 2157
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 628,
          "y" : 2160
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 628,
          "y" : 2160
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 138238,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 623,
          "y" : 2152
        },
        "to" : {
          "x" : 654,
          "y" : 2119
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 625,
          "y" : 2144
        },
        "b" : {
          "x" : 623,
          "y" : 2152
        },
        "c" : {
          "x" : 631,
          "y" : 2150
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 631,
          "y" : 2150
        }
      }
    } ]
  }, {
    "id" : 138240,
    "reactomeId" : 10783641,
    "displayName" : "Centrosome:p-T288-AURKA:p-S252-BORA:PLK1",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 750,
      "y" : 2094
    },
    "minX" : 673,
    "maxX" : 799,
    "minY" : 2051,
    "maxY" : 2141,
    "prop" : {
      "x" : 708,
      "y" : 2057,
      "width" : 85,
      "height" : 74
    },
    "textPosition" : {
      "x" : 708,
      "y" : 2054
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 793,
          "y" : 2057
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 793,
          "y" : 2057
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 138253,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 138238,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 709,
          "y" : 2134
        },
        "to" : {
          "x" : 699,
          "y" : 2141
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 138238,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 705,
          "y" : 2105
        },
        "to" : {
          "x" : 679,
          "y" : 2113
        }
      }, {
        "from" : {
          "x" : 679,
          "y" : 2113
        },
        "to" : {
          "x" : 677,
          "y" : 2124
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 677,
          "y" : 2128
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 677,
          "y" : 2128
        }
      }
    } ]
  }, {
    "id" : 138241,
    "reactomeId" : 10783643,
    "displayName" : "p-7S,2T-BORA:p-T210-PLK1",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 560,
      "y" : 1987
    },
    "minX" : 423,
    "maxX" : 654,
    "minY" : 1965,
    "maxY" : 2119,
    "prop" : {
      "x" : 509,
      "y" : 1971,
      "width" : 103,
      "height" : 33
    },
    "textPosition" : {
      "x" : 512,
      "y" : 1969
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 612,
          "y" : 1971
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 612,
          "y" : 1971
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 138243,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 545,
          "y" : 2007
        },
        "to" : {
          "x" : 456,
          "y" : 2102
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 138243,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 533,
          "y" : 2007
        },
        "to" : {
          "x" : 429,
          "y" : 2069
        }
      }, {
        "from" : {
          "x" : 429,
          "y" : 2069
        },
        "to" : {
          "x" : 427,
          "y" : 2088
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 427,
          "y" : 2092
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 427,
          "y" : 2092
        }
      }
    }, {
      "edgeId" : 138238,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 571,
          "y" : 2007
        },
        "to" : {
          "x" : 654,
          "y" : 2119
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 578,
          "y" : 2010
        },
        "b" : {
          "x" : 571,
          "y" : 2007
        },
        "c" : {
          "x" : 572,
          "y" : 2015
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 572,
          "y" : 2015
        }
      }
    } ]
  }, {
    "id" : 138246,
    "reactomeId" : 29370,
    "displayName" : "ADP",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 392,
      "y" : 2047
    },
    "minX" : 372,
    "maxX" : 413,
    "minY" : 2035,
    "maxY" : 2107,
    "prop" : {
      "x" : 372,
      "y" : 2036,
      "width" : 40,
      "height" : 23
    },
    "textPosition" : {
      "x" : 375,
      "y" : 2037
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 407,
          "y" : 2041
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 407,
          "y" : 2041
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 138243,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 392,
          "y" : 2062
        },
        "to" : {
          "x" : 397,
          "y" : 2107
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 397,
          "y" : 2068
        },
        "b" : {
          "x" : 392,
          "y" : 2062
        },
        "c" : {
          "x" : 389,
          "y" : 2069
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 389,
          "y" : 2069
        }
      }
    } ]
  }, {
    "id" : 138244,
    "reactomeId" : 113592,
    "displayName" : "ATP",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 532,
      "y" : 2088
    },
    "minX" : 456,
    "maxX" : 553,
    "minY" : 2077,
    "maxY" : 2102,
    "prop" : {
      "x" : 512,
      "y" : 2078,
      "width" : 40,
      "height" : 20
    },
    "textPosition" : {
      "x" : 516,
      "y" : 2078
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 547,
          "y" : 2083
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 547,
          "y" : 2083
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 138243,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 509,
          "y" : 2091
        },
        "to" : {
          "x" : 456,
          "y" : 2102
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 138245,
    "reactomeId" : 10783652,
    "displayName" : "phospho-BORA",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 285,
      "y" : 2065
    },
    "minX" : 233,
    "maxX" : 397,
    "minY" : 2036,
    "maxY" : 2107,
    "prop" : {
      "x" : 233,
      "y" : 2042,
      "width" : 105,
      "height" : 47
    },
    "textPosition" : {
      "x" : 235,
      "y" : 2055
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 338,
          "y" : 2042
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 338,
          "y" : 2042
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 138243,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 341,
          "y" : 2084
        },
        "to" : {
          "x" : 397,
          "y" : 2107
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 349,
          "y" : 2083
        },
        "b" : {
          "x" : 341,
          "y" : 2084
        },
        "c" : {
          "x" : 346,
          "y" : 2090
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 346,
          "y" : 2090
        }
      }
    } ]
  }, {
    "id" : 138250,
    "reactomeId" : 10782508,
    "displayName" : "RAB8A:GTP",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 89,
      "y" : 2153
    },
    "minX" : 51,
    "maxX" : 158,
    "minY" : 2136,
    "maxY" : 2164,
    "prop" : {
      "x" : 51,
      "y" : 2142,
      "width" : 76,
      "height" : 22
    },
    "textPosition" : {
      "x" : 51,
      "y" : 2143
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 127,
          "y" : 2142
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 127,
          "y" : 2142
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 138247,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 130,
          "y" : 2151
        },
        "to" : {
          "x" : 158,
          "y" : 2151
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 137,
          "y" : 2147
        },
        "b" : {
          "x" : 130,
          "y" : 2151
        },
        "c" : {
          "x" : 137,
          "y" : 2155
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 137,
          "y" : 2155
        }
      }
    } ]
  }, {
    "id" : 138251,
    "reactomeId" : 10782513,
    "displayName" : "phospho-OPTN",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 158,
      "y" : 1843
    },
    "minX" : 105,
    "maxX" : 217,
    "minY" : 1827,
    "maxY" : 2151,
    "prop" : {
      "x" : 105,
      "y" : 1833,
      "width" : 106,
      "height" : 21
    },
    "textPosition" : {
      "x" : 108,
      "y" : 1833
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 211,
          "y" : 1833
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 211,
          "y" : 1833
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 138247,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 158,
          "y" : 1857
        },
        "to" : {
          "x" : 158,
          "y" : 2151
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 162,
          "y" : 1864
        },
        "b" : {
          "x" : 158,
          "y" : 1857
        },
        "c" : {
          "x" : 154,
          "y" : 1864
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 154,
          "y" : 1864
        }
      }
    }, {
      "edgeId" : 138255,
      "type" : "INPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 138248,
    "reactomeId" : 10782510,
    "displayName" : "OPTN:RAB8A:GTP",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 276,
      "y" : 2152
    },
    "minX" : 201,
    "maxX" : 322,
    "minY" : 2130,
    "maxY" : 2168,
    "prop" : {
      "x" : 237,
      "y" : 2136,
      "width" : 79,
      "height" : 32
    },
    "textPosition" : {
      "x" : 238,
      "y" : 2133
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 316,
          "y" : 2136
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 316,
          "y" : 2136
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 138247,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 234,
          "y" : 2152
        },
        "to" : {
          "x" : 201,
          "y" : 2152
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 138249,
    "reactomeId" : 113592,
    "displayName" : "ATP",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 208,
      "y" : 2111
    },
    "minX" : 186,
    "maxX" : 232,
    "minY" : 2099,
    "maxY" : 2152,
    "prop" : {
      "x" : 186,
      "y" : 2100,
      "width" : 45,
      "height" : 22
    },
    "textPosition" : {
      "x" : 193,
      "y" : 2100
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 226,
          "y" : 2105
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 226,
          "y" : 2105
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 138247,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 206,
          "y" : 2125
        },
        "to" : {
          "x" : 201,
          "y" : 2152
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 138254,
    "reactomeId" : 10783637,
    "displayName" : "phospho-BORA",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 904,
      "y" : 2190
    },
    "minX" : 772,
    "maxX" : 966,
    "minY" : 2123,
    "maxY" : 2212,
    "prop" : {
      "x" : 849,
      "y" : 2169,
      "width" : 111,
      "height" : 43
    },
    "textPosition" : {
      "x" : 854,
      "y" : 2180
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 960,
          "y" : 2169
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 960,
          "y" : 2169
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 138253,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 846,
          "y" : 2191
        },
        "to" : {
          "x" : 772,
          "y" : 2193
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 138264,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 899,
          "y" : 2166
        },
        "to" : {
          "x" : 890,
          "y" : 2123
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 894,
          "y" : 2160
        },
        "b" : {
          "x" : 899,
          "y" : 2166
        },
        "c" : {
          "x" : 901,
          "y" : 2158
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 901,
          "y" : 2158
        }
      }
    }, {
      "edgeId" : 138340,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 908,
          "y" : 2166
        },
        "to" : {
          "x" : 914,
          "y" : 2141
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 906,
          "y" : 2158
        },
        "b" : {
          "x" : 908,
          "y" : 2166
        },
        "c" : {
          "x" : 914,
          "y" : 2160
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 914,
          "y" : 2160
        }
      }
    } ]
  }, {
    "id" : 138252,
    "reactomeId" : 29370,
    "displayName" : "ADP",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 94,
      "y" : 2109
    },
    "minX" : 74,
    "maxX" : 158,
    "minY" : 2096,
    "maxY" : 2151,
    "prop" : {
      "x" : 74,
      "y" : 2097,
      "width" : 41,
      "height" : 24
    },
    "textPosition" : {
      "x" : 78,
      "y" : 2098
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 110,
          "y" : 2102
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 110,
          "y" : 2102
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 138247,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 112,
          "y" : 2124
        },
        "to" : {
          "x" : 158,
          "y" : 2151
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 120,
          "y" : 2124
        },
        "b" : {
          "x" : 112,
          "y" : 2124
        },
        "c" : {
          "x" : 116,
          "y" : 2131
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 116,
          "y" : 2131
        }
      }
    } ]
  }, {
    "id" : 138258,
    "reactomeId" : 10740531,
    "displayName" : "phospho-PLK1",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 762,
      "y" : 1726
    },
    "minX" : 711,
    "maxX" : 980,
    "minY" : 1596,
    "maxY" : 1787,
    "prop" : {
      "x" : 711,
      "y" : 1714,
      "width" : 102,
      "height" : 24
    },
    "textPosition" : {
      "x" : 714,
      "y" : 1715
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 813,
          "y" : 1714
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 813,
          "y" : 1714
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 138259,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 777,
          "y" : 1741
        },
        "to" : {
          "x" : 843,
          "y" : 1787
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 138257,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 138275,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 756,
          "y" : 1711
        },
        "to" : {
          "x" : 731,
          "y" : 1654
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 138277,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 782,
          "y" : 1711
        },
        "to" : {
          "x" : 980,
          "y" : 1596
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 786,
          "y" : 1704
        },
        "b" : {
          "x" : 782,
          "y" : 1711
        },
        "c" : {
          "x" : 790,
          "y" : 1711
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 790,
          "y" : 1711
        }
      }
    } ]
  }, {
    "id" : 138256,
    "reactomeId" : 10782527,
    "displayName" : "phospho-OPTN",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 884,
      "y" : 1850
    },
    "minX" : 832,
    "maxX" : 942,
    "minY" : 1795,
    "maxY" : 1862,
    "prop" : {
      "x" : 832,
      "y" : 1839,
      "width" : 104,
      "height" : 23
    },
    "textPosition" : {
      "x" : 834,
      "y" : 1840
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 936,
          "y" : 1839
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 936,
          "y" : 1839
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 138255,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 138259,
      "type" : "ACTIVATOR",
      "segments" : [ {
        "from" : {
          "x" : 884,
          "y" : 1836
        },
        "to" : {
          "x" : 886,
          "y" : 1795
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 890,
          "y" : 1802
        },
        "b" : {
          "x" : 886,
          "y" : 1795
        },
        "c" : {
          "x" : 882,
          "y" : 1802
        },
        "type" : "ARROW",
        "empty" : true,
        "centre" : {
          "x" : 882,
          "y" : 1802
        }
      }
    } ]
  }, {
    "id" : 138262,
    "reactomeId" : 113550,
    "displayName" : "Pi",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 933,
      "y" : 1818
    },
    "minX" : 917,
    "maxX" : 950,
    "minY" : 1786,
    "maxY" : 1828,
    "prop" : {
      "x" : 917,
      "y" : 1808,
      "width" : 32,
      "height" : 20
    },
    "textPosition" : {
      "x" : 923,
      "y" : 1808
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 944,
          "y" : 1813
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 944,
          "y" : 1813
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 138259,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 930,
          "y" : 1805
        },
        "to" : {
          "x" : 925,
          "y" : 1786
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 924,
          "y" : 1799
        },
        "b" : {
          "x" : 930,
          "y" : 1805
        },
        "c" : {
          "x" : 932,
          "y" : 1797
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 932,
          "y" : 1797
        }
      }
    } ]
  }, {
    "id" : 138263,
    "reactomeId" : 10783750,
    "displayName" : "Phosphorylated Myosin Phosphatase",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 889,
      "y" : 1725
    },
    "minX" : 827,
    "maxX" : 958,
    "minY" : 1701,
    "maxY" : 1778,
    "prop" : {
      "x" : 827,
      "y" : 1707,
      "width" : 125,
      "height" : 36
    },
    "textPosition" : {
      "x" : 834,
      "y" : 1694
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 952,
          "y" : 1707
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 952,
          "y" : 1707
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 138259,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 888,
          "y" : 1746
        },
        "to" : {
          "x" : 887,
          "y" : 1770
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 887,
          "y" : 1774
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 887,
          "y" : 1774
        }
      }
    } ]
  }, {
    "id" : 138260,
    "reactomeId" : 113518,
    "displayName" : "H2O",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 784,
      "y" : 1818
    },
    "minX" : 763,
    "maxX" : 843,
    "minY" : 1787,
    "maxY" : 1830,
    "prop" : {
      "x" : 763,
      "y" : 1807,
      "width" : 42,
      "height" : 23
    },
    "textPosition" : {
      "x" : 767,
      "y" : 1808
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 800,
          "y" : 1812
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 800,
          "y" : 1812
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 138259,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 805,
          "y" : 1804
        },
        "to" : {
          "x" : 843,
          "y" : 1787
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ],
    "trivial" : true
  }, {
    "id" : 138261,
    "reactomeId" : 10783735,
    "displayName" : "PLK1",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 942,
      "y" : 1764
    },
    "minX" : 916,
    "maxX" : 974,
    "minY" : 1748,
    "maxY" : 1786,
    "prop" : {
      "x" : 916,
      "y" : 1754,
      "width" : 52,
      "height" : 21
    },
    "textPosition" : {
      "x" : 923,
      "y" : 1754
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 968,
          "y" : 1754
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 968,
          "y" : 1754
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 138259,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 933,
          "y" : 1778
        },
        "to" : {
          "x" : 925,
          "y" : 1786
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 931,
          "y" : 1786
        },
        "b" : {
          "x" : 933,
          "y" : 1778
        },
        "c" : {
          "x" : 925,
          "y" : 1780
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 925,
          "y" : 1780
        }
      }
    } ]
  }, {
    "id" : 138266,
    "reactomeId" : 113592,
    "displayName" : "ATP",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 831,
      "y" : 2066
    },
    "minX" : 813,
    "maxX" : 902,
    "minY" : 2049,
    "maxY" : 2081,
    "prop" : {
      "x" : 813,
      "y" : 2052,
      "width" : 36,
      "height" : 29
    },
    "textPosition" : {
      "x" : 815,
      "y" : 2056
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 844,
          "y" : 2057
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 844,
          "y" : 2057
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 138264,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 852,
          "y" : 2066
        },
        "to" : {
          "x" : 894,
          "y" : 2069
        }
      } ],
      "stoichiometry" : {
        "value" : 9,
        "shape" : {
          "a" : {
            "x" : 867,
            "y" : 2061
          },
          "b" : {
            "x" : 879,
            "y" : 2073
          },
          "type" : "BOX",
          "empty" : true,
          "centre" : {
            "x" : 873,
            "y" : 2067
          }
        }
      }
    }, {
      "edgeId" : 138340,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 852,
          "y" : 2061
        },
        "to" : {
          "x" : 902,
          "y" : 2050
        }
      } ],
      "stoichiometry" : {
        "value" : 9,
        "shape" : {
          "a" : {
            "x" : 871,
            "y" : 2049
          },
          "b" : {
            "x" : 883,
            "y" : 2061
          },
          "type" : "BOX",
          "empty" : true,
          "centre" : {
            "x" : 877,
            "y" : 2055
          }
        }
      }
    } ]
  }, {
    "id" : 138267,
    "reactomeId" : 29370,
    "displayName" : "ADP",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 834,
      "y" : 2139
    },
    "minX" : 817,
    "maxX" : 914,
    "minY" : 2122,
    "maxY" : 2154,
    "prop" : {
      "x" : 817,
      "y" : 2125,
      "width" : 35,
      "height" : 29
    },
    "textPosition" : {
      "x" : 818,
      "y" : 2129
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 847,
          "y" : 2130
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 847,
          "y" : 2130
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 138264,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 855,
          "y" : 2134
        },
        "to" : {
          "x" : 890,
          "y" : 2123
        }
      } ],
      "stoichiometry" : {
        "value" : 9,
        "shape" : {
          "a" : {
            "x" : 866,
            "y" : 2122
          },
          "b" : {
            "x" : 878,
            "y" : 2134
          },
          "type" : "BOX",
          "empty" : true,
          "centre" : {
            "x" : 872,
            "y" : 2128
          }
        }
      },
      "endShape" : {
        "a" : {
          "x" : 860,
          "y" : 2128
        },
        "b" : {
          "x" : 855,
          "y" : 2134
        },
        "c" : {
          "x" : 863,
          "y" : 2136
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 863,
          "y" : 2136
        }
      }
    }, {
      "edgeId" : 138340,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 855,
          "y" : 2139
        },
        "to" : {
          "x" : 914,
          "y" : 2141
        }
      } ],
      "stoichiometry" : {
        "value" : 9,
        "shape" : {
          "a" : {
            "x" : 878,
            "y" : 2134
          },
          "b" : {
            "x" : 890,
            "y" : 2146
          },
          "type" : "BOX",
          "empty" : true,
          "centre" : {
            "x" : 884,
            "y" : 2140
          }
        }
      },
      "endShape" : {
        "a" : {
          "x" : 862,
          "y" : 2135
        },
        "b" : {
          "x" : 855,
          "y" : 2139
        },
        "c" : {
          "x" : 862,
          "y" : 2143
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 862,
          "y" : 2143
        }
      }
    } ]
  }, {
    "id" : 138265,
    "reactomeId" : 10786670,
    "displayName" : "BORA",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 880,
      "y" : 2020
    },
    "minX" : 859,
    "maxX" : 907,
    "minY" : 2003,
    "maxY" : 2069,
    "prop" : {
      "x" : 859,
      "y" : 2009,
      "width" : 42,
      "height" : 22
    },
    "textPosition" : {
      "x" : 859,
      "y" : 2009
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 901,
          "y" : 2009
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 901,
          "y" : 2009
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 138264,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 883,
          "y" : 2034
        },
        "to" : {
          "x" : 894,
          "y" : 2069
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 138340,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 888,
          "y" : 2034
        },
        "to" : {
          "x" : 902,
          "y" : 2050
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 138270,
    "reactomeId" : 29358,
    "displayName" : "ATP",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 778,
      "y" : 1344
    },
    "minX" : 750,
    "maxX" : 801,
    "minY" : 1331,
    "maxY" : 1407,
    "prop" : {
      "x" : 757,
      "y" : 1332,
      "width" : 43,
      "height" : 24
    },
    "textPosition" : {
      "x" : 763,
      "y" : 1333
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 795,
          "y" : 1337
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 795,
          "y" : 1337
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 138269,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 772,
          "y" : 1359
        },
        "to" : {
          "x" : 750,
          "y" : 1407
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 138271,
    "reactomeId" : 10786676,
    "displayName" : "FOXM1",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 722,
      "y" : 1346
    },
    "minX" : 697,
    "maxX" : 753,
    "minY" : 1329,
    "maxY" : 1407,
    "prop" : {
      "x" : 697,
      "y" : 1335,
      "width" : 50,
      "height" : 22
    },
    "textPosition" : {
      "x" : 697,
      "y" : 1335
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 747,
          "y" : 1335
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 747,
          "y" : 1335
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 138269,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 727,
          "y" : 1360
        },
        "to" : {
          "x" : 750,
          "y" : 1407
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 138268,
    "reactomeId" : 10742777,
    "displayName" : "CCNB2:p-T161-CDK1",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 1477,
      "y" : 2282
    },
    "minX" : 900,
    "maxX" : 1533,
    "minY" : 2105,
    "maxY" : 2299,
    "prop" : {
      "x" : 1427,
      "y" : 2266,
      "width" : 100,
      "height" : 33
    },
    "textPosition" : {
      "x" : 1427,
      "y" : 2265
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1527,
          "y" : 2266
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1527,
          "y" : 2266
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 138264,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 1421,
          "y" : 2283
        },
        "to" : {
          "x" : 1044,
          "y" : 2295
        }
      }, {
        "from" : {
          "x" : 1044,
          "y" : 2295
        },
        "to" : {
          "x" : 987,
          "y" : 2159
        }
      }, {
        "from" : {
          "x" : 987,
          "y" : 2159
        },
        "to" : {
          "x" : 908,
          "y" : 2111
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 904,
          "y" : 2109
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 904,
          "y" : 2109
        }
      }
    } ]
  }, {
    "id" : 138274,
    "reactomeId" : 10786681,
    "displayName" : "CCNA:p-CDK1/2",
    "schemaClass" : "DefinedSet",
    "renderableClass" : "EntitySet",
    "position" : {
      "x" : 867,
      "y" : 1437
    },
    "minX" : 757,
    "maxX" : 938,
    "minY" : 1419,
    "maxY" : 1456,
    "prop" : {
      "x" : 797,
      "y" : 1419,
      "width" : 141,
      "height" : 37
    },
    "textPosition" : {
      "x" : 817,
      "y" : 1427
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "fgColor" : {
      "r" : 0,
      "g" : 0,
      "b" : 0
    },
    "connectors" : [ {
      "edgeId" : 138269,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 791,
          "y" : 1435
        },
        "to" : {
          "x" : 765,
          "y" : 1435
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 761,
          "y" : 1435
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 761,
          "y" : 1435
        }
      }
    } ]
  }, {
    "id" : 138272,
    "reactomeId" : 113582,
    "displayName" : "ADP",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 840,
      "y" : 1518
    },
    "minX" : 749,
    "maxX" : 862,
    "minY" : 1460,
    "maxY" : 1530,
    "prop" : {
      "x" : 819,
      "y" : 1507,
      "width" : 42,
      "height" : 23
    },
    "textPosition" : {
      "x" : 823,
      "y" : 1508
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 856,
          "y" : 1512
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 856,
          "y" : 1512
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 138269,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 821,
          "y" : 1504
        },
        "to" : {
          "x" : 749,
          "y" : 1460
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 813,
          "y" : 1504
        },
        "b" : {
          "x" : 821,
          "y" : 1504
        },
        "c" : {
          "x" : 817,
          "y" : 1497
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 817,
          "y" : 1497
        }
      }
    } ]
  }, {
    "id" : 138273,
    "reactomeId" : 10786679,
    "displayName" : "phospho-FOXM1",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 739,
      "y" : 1527
    },
    "minX" : 681,
    "maxX" : 803,
    "minY" : 1460,
    "maxY" : 1654,
    "prop" : {
      "x" : 681,
      "y" : 1516,
      "width" : 116,
      "height" : 22
    },
    "textPosition" : {
      "x" : 685,
      "y" : 1516
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 797,
          "y" : 1516
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 797,
          "y" : 1516
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 138269,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 740,
          "y" : 1513
        },
        "to" : {
          "x" : 749,
          "y" : 1460
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 737,
          "y" : 1505
        },
        "b" : {
          "x" : 740,
          "y" : 1513
        },
        "c" : {
          "x" : 745,
          "y" : 1507
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 745,
          "y" : 1507
        }
      }
    }, {
      "edgeId" : 138275,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 738,
          "y" : 1541
        },
        "to" : {
          "x" : 731,
          "y" : 1654
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 138278,
    "reactomeId" : 29358,
    "displayName" : "ATP",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 831,
      "y" : 1649
    },
    "minX" : 808,
    "maxX" : 909,
    "minY" : 1602,
    "maxY" : 1660,
    "prop" : {
      "x" : 808,
      "y" : 1639,
      "width" : 47,
      "height" : 21
    },
    "textPosition" : {
      "x" : 816,
      "y" : 1639
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 850,
          "y" : 1644
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 850,
          "y" : 1644
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 138277,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 848,
          "y" : 1636
        },
        "to" : {
          "x" : 909,
          "y" : 1602
        }
      } ],
      "stoichiometry" : {
        "value" : 2,
        "shape" : {
          "a" : {
            "x" : 872,
            "y" : 1613
          },
          "b" : {
            "x" : 884,
            "y" : 1625
          },
          "type" : "BOX",
          "empty" : true,
          "centre" : {
            "x" : 878,
            "y" : 1619
          }
        }
      }
    } ]
  }, {
    "id" : 138279,
    "reactomeId" : 10786694,
    "displayName" : "phospho-FOXM1",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 1030,
      "y" : 1440
    },
    "minX" : 980,
    "maxX" : 1086,
    "minY" : 1414,
    "maxY" : 1596,
    "prop" : {
      "x" : 981,
      "y" : 1420,
      "width" : 99,
      "height" : 41
    },
    "textPosition" : {
      "x" : 997,
      "y" : 1423
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1080,
          "y" : 1420
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1080,
          "y" : 1420
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 138277,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 1023,
          "y" : 1464
        },
        "to" : {
          "x" : 980,
          "y" : 1596
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 1025,
          "y" : 1472
        },
        "b" : {
          "x" : 1023,
          "y" : 1464
        },
        "c" : {
          "x" : 1017,
          "y" : 1469
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 1017,
          "y" : 1469
        }
      }
    } ]
  }, {
    "id" : 138276,
    "reactomeId" : 10786688,
    "displayName" : "p-T611-FOXM1:p-T210-PLK1",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 820,
      "y" : 1590
    },
    "minX" : 763,
    "maxX" : 947,
    "minY" : 1565,
    "maxY" : 1608,
    "prop" : {
      "x" : 763,
      "y" : 1572,
      "width" : 114,
      "height" : 36
    },
    "textPosition" : {
      "x" : 764,
      "y" : 1573
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 877,
          "y" : 1572
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 877,
          "y" : 1572
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 138275,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 138277,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 880,
          "y" : 1597
        },
        "to" : {
          "x" : 909,
          "y" : 1602
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 138277,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 880,
          "y" : 1578
        },
        "to" : {
          "x" : 941,
          "y" : 1565
        }
      }, {
        "from" : {
          "x" : 941,
          "y" : 1565
        },
        "to" : {
          "x" : 943,
          "y" : 1581
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 943,
          "y" : 1585
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 943,
          "y" : 1585
        }
      }
    } ]
  }, {
    "id" : 138282,
    "reactomeId" : 10805747,
    "displayName" : "GTSE1",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 1080,
      "y" : 2025
    },
    "minX" : 776,
    "maxX" : 1839,
    "minY" : 1983,
    "maxY" : 2624,
    "prop" : {
      "x" : 1056,
      "y" : 2014,
      "width" : 49,
      "height" : 22
    },
    "textPosition" : {
      "x" : 1056,
      "y" : 2014
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1105,
          "y" : 2014
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1105,
          "y" : 2014
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 138281,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1053,
          "y" : 2021
        },
        "to" : {
          "x" : 776,
          "y" : 1983
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 138290,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1078,
          "y" : 2039
        },
        "to" : {
          "x" : 1058,
          "y" : 2229
        }
      }, {
        "from" : {
          "x" : 1058,
          "y" : 2229
        },
        "to" : {
          "x" : 1279,
          "y" : 2624
        }
      }, {
        "from" : {
          "x" : 1279,
          "y" : 2624
        },
        "to" : {
          "x" : 1839,
          "y" : 2613
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 138283,
    "reactomeId" : 10805749,
    "displayName" : "GTSE1:p-T210-PLK1",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 883,
      "y" : 1938
    },
    "minX" : 808,
    "maxX" : 1039,
    "minY" : 1914,
    "maxY" : 1950,
    "prop" : {
      "x" : 808,
      "y" : 1926,
      "width" : 150,
      "height" : 24
    },
    "textPosition" : {
      "x" : 819,
      "y" : 1929
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 958,
          "y" : 1926
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 958,
          "y" : 1926
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 138281,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 138284,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 961,
          "y" : 1939
        },
        "to" : {
          "x" : 996,
          "y" : 1940
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 138284,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 961,
          "y" : 1926
        },
        "to" : {
          "x" : 1034,
          "y" : 1914
        }
      }, {
        "from" : {
          "x" : 1034,
          "y" : 1914
        },
        "to" : {
          "x" : 1034,
          "y" : 1923
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 1035,
          "y" : 1927
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1035,
          "y" : 1927
        }
      }
    } ]
  }, {
    "id" : 138280,
    "reactomeId" : 113582,
    "displayName" : "ADP",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 1005,
      "y" : 1644
    },
    "minX" : 980,
    "maxX" : 1028,
    "minY" : 1596,
    "maxY" : 1654,
    "prop" : {
      "x" : 984,
      "y" : 1634,
      "width" : 43,
      "height" : 20
    },
    "textPosition" : {
      "x" : 989,
      "y" : 1634
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1022,
          "y" : 1639
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1022,
          "y" : 1639
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 138277,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 999,
          "y" : 1631
        },
        "to" : {
          "x" : 980,
          "y" : 1596
        }
      } ],
      "stoichiometry" : {
        "value" : 2,
        "shape" : {
          "a" : {
            "x" : 983,
            "y" : 1607
          },
          "b" : {
            "x" : 995,
            "y" : 1619
          },
          "type" : "BOX",
          "empty" : true,
          "centre" : {
            "x" : 989,
            "y" : 1613
          }
        }
      },
      "endShape" : {
        "a" : {
          "x" : 992,
          "y" : 1627
        },
        "b" : {
          "x" : 999,
          "y" : 1631
        },
        "c" : {
          "x" : 999,
          "y" : 1623
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 999,
          "y" : 1623
        }
      }
    } ]
  }, {
    "id" : 138286,
    "reactomeId" : 29370,
    "displayName" : "ADP",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 1215,
      "y" : 1963
    },
    "minX" : 1126,
    "maxX" : 1237,
    "minY" : 1939,
    "maxY" : 1976,
    "prop" : {
      "x" : 1194,
      "y" : 1951,
      "width" : 42,
      "height" : 25
    },
    "textPosition" : {
      "x" : 1198,
      "y" : 1953
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1231,
          "y" : 1956
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1231,
          "y" : 1956
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 138284,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 1191,
          "y" : 1957
        },
        "to" : {
          "x" : 1126,
          "y" : 1939
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 1183,
          "y" : 1959
        },
        "b" : {
          "x" : 1191,
          "y" : 1957
        },
        "c" : {
          "x" : 1185,
          "y" : 1951
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 1185,
          "y" : 1951
        }
      }
    } ]
  }, {
    "id" : 138287,
    "reactomeId" : 10805752,
    "displayName" : "phospho-GTSE1",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 1233,
      "y" : 1919
    },
    "minX" : 1126,
    "maxX" : 1295,
    "minY" : 1899,
    "maxY" : 1939,
    "prop" : {
      "x" : 1178,
      "y" : 1905,
      "width" : 111,
      "height" : 28
    },
    "textPosition" : {
      "x" : 1180,
      "y" : 1908
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1289,
          "y" : 1905
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1289,
          "y" : 1905
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 138284,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 1175,
          "y" : 1929
        },
        "to" : {
          "x" : 1126,
          "y" : 1939
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 1169,
          "y" : 1934
        },
        "b" : {
          "x" : 1175,
          "y" : 1929
        },
        "c" : {
          "x" : 1167,
          "y" : 1926
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 1167,
          "y" : 1926
        }
      }
    }, {
      "edgeId" : 138288,
      "type" : "INPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 138285,
    "reactomeId" : 113592,
    "displayName" : "ATP",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 947,
      "y" : 1972
    },
    "minX" : 926,
    "maxX" : 996,
    "minY" : 1940,
    "maxY" : 1983,
    "prop" : {
      "x" : 926,
      "y" : 1961,
      "width" : 42,
      "height" : 22
    },
    "textPosition" : {
      "x" : 931,
      "y" : 1961
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 963,
          "y" : 1966
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 963,
          "y" : 1966
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 138284,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 963,
          "y" : 1958
        },
        "to" : {
          "x" : 996,
          "y" : 1940
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 138291,
    "reactomeId" : 10785168,
    "displayName" : "HSP90:HSP90",
    "schemaClass" : "DefinedSet",
    "renderableClass" : "EntitySet",
    "position" : {
      "x" : 1786,
      "y" : 2557
    },
    "minX" : 1756,
    "maxX" : 1839,
    "minY" : 2540,
    "maxY" : 2613,
    "prop" : {
      "x" : 1756,
      "y" : 2540,
      "width" : 61,
      "height" : 34
    },
    "textPosition" : {
      "x" : 1760,
      "y" : 2540
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "fgColor" : {
      "r" : 0,
      "g" : 0,
      "b" : 0
    },
    "connectors" : [ {
      "edgeId" : 138290,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1802,
          "y" : 2580
        },
        "to" : {
          "x" : 1839,
          "y" : 2613
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 138289,
    "reactomeId" : 10805759,
    "displayName" : "phospho-GTSE1",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 1715,
      "y" : 1392
    },
    "minX" : 1659,
    "maxX" : 1778,
    "minY" : 1373,
    "maxY" : 1406,
    "prop" : {
      "x" : 1659,
      "y" : 1379,
      "width" : 113,
      "height" : 27
    },
    "textPosition" : {
      "x" : 1662,
      "y" : 1382
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1772,
          "y" : 1379
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1772,
          "y" : 1379
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 138288,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 138294,
    "reactomeId" : 10805767,
    "displayName" : "GTSE1:CDKN1A:FKBPL:HSP90",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 2019,
      "y" : 2611
    },
    "minX" : 1965,
    "maxX" : 2079,
    "minY" : 2587,
    "maxY" : 2629,
    "prop" : {
      "x" : 1965,
      "y" : 2593,
      "width" : 108,
      "height" : 36
    },
    "textPosition" : {
      "x" : 1966,
      "y" : 2594
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 2073,
          "y" : 2593
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 2073,
          "y" : 2593
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 138290,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 138292,
    "reactomeId" : 10744972,
    "displayName" : "CDKN1A",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 2052,
      "y" : 2383
    },
    "minX" : 1839,
    "maxX" : 2088,
    "minY" : 2366,
    "maxY" : 2613,
    "prop" : {
      "x" : 2023,
      "y" : 2372,
      "width" : 59,
      "height" : 22
    },
    "textPosition" : {
      "x" : 2024,
      "y" : 2372
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 2082,
          "y" : 2372
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 2082,
          "y" : 2372
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 138290,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 2041,
          "y" : 2397
        },
        "to" : {
          "x" : 1839,
          "y" : 2613
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 138293,
    "reactomeId" : 10805765,
    "displayName" : "TTC9",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 1787,
      "y" : 2662
    },
    "minX" : 1765,
    "maxX" : 1839,
    "minY" : 2613,
    "maxY" : 2673,
    "prop" : {
      "x" : 1765,
      "y" : 2651,
      "width" : 45,
      "height" : 22
    },
    "textPosition" : {
      "x" : 1768,
      "y" : 2651
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1810,
          "y" : 2651
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1810,
          "y" : 2651
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 138290,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1798,
          "y" : 2648
        },
        "to" : {
          "x" : 1839,
          "y" : 2613
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 138298,
    "reactomeId" : 10805842,
    "displayName" : "Centrosome:AURKA:TPX2:HMMR",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 385,
      "y" : 2363
    },
    "minX" : 344,
    "maxX" : 490,
    "minY" : 2332,
    "maxY" : 2390,
    "prop" : {
      "x" : 344,
      "y" : 2338,
      "width" : 82,
      "height" : 50
    },
    "textPosition" : {
      "x" : 345,
      "y" : 2339
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 426,
          "y" : 2338
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 426,
          "y" : 2338
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 138295,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 138299,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 429,
          "y" : 2360
        },
        "to" : {
          "x" : 455,
          "y" : 2359
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 138299,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 429,
          "y" : 2373
        },
        "to" : {
          "x" : 487,
          "y" : 2390
        }
      }, {
        "from" : {
          "x" : 487,
          "y" : 2390
        },
        "to" : {
          "x" : 487,
          "y" : 2376
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 486,
          "y" : 2372
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 486,
          "y" : 2372
        }
      }
    } ]
  }, {
    "id" : 138296,
    "reactomeId" : 10805840,
    "displayName" : "HMMR",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 207,
      "y" : 2328
    },
    "minX" : 184,
    "maxX" : 275,
    "minY" : 2311,
    "maxY" : 2339,
    "prop" : {
      "x" : 184,
      "y" : 2317,
      "width" : 47,
      "height" : 22
    },
    "textPosition" : {
      "x" : 185,
      "y" : 2317
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 231,
          "y" : 2317
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 231,
          "y" : 2317
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 138295,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 234,
          "y" : 2327
        },
        "to" : {
          "x" : 275,
          "y" : 2327
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 138297,
    "reactomeId" : 10805838,
    "displayName" : "TPX2",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 234,
      "y" : 2362
    },
    "minX" : 214,
    "maxX" : 275,
    "minY" : 2327,
    "maxY" : 2373,
    "prop" : {
      "x" : 214,
      "y" : 2351,
      "width" : 40,
      "height" : 22
    },
    "textPosition" : {
      "x" : 215,
      "y" : 2351
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 254,
          "y" : 2351
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 254,
          "y" : 2351
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 138295,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 246,
          "y" : 2348
        },
        "to" : {
          "x" : 275,
          "y" : 2327
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 138302,
    "reactomeId" : 10743447,
    "displayName" : "AURKA",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 314,
      "y" : 2431
    },
    "minX" : 188,
    "maxX" : 345,
    "minY" : 2378,
    "maxY" : 2659,
    "prop" : {
      "x" : 290,
      "y" : 2420,
      "width" : 49,
      "height" : 22
    },
    "textPosition" : {
      "x" : 290,
      "y" : 2420
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 339,
          "y" : 2420
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 339,
          "y" : 2420
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 138301,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 292,
          "y" : 2445
        },
        "to" : {
          "x" : 267,
          "y" : 2455
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 138305,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 314,
          "y" : 2445
        },
        "to" : {
          "x" : 315,
          "y" : 2602
        }
      }, {
        "from" : {
          "x" : 315,
          "y" : 2602
        },
        "to" : {
          "x" : 265,
          "y" : 2659
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 318,
          "y" : 2452
        },
        "b" : {
          "x" : 314,
          "y" : 2445
        },
        "c" : {
          "x" : 310,
          "y" : 2452
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 310,
          "y" : 2452
        }
      }
    }, {
      "edgeId" : 138309,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 287,
          "y" : 2420
        },
        "to" : {
          "x" : 188,
          "y" : 2378
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 138303,
    "reactomeId" : 10805853,
    "displayName" : "PHLDA1",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 242,
      "y" : 2433
    },
    "minX" : 214,
    "maxX" : 276,
    "minY" : 2416,
    "maxY" : 2455,
    "prop" : {
      "x" : 214,
      "y" : 2422,
      "width" : 56,
      "height" : 22
    },
    "textPosition" : {
      "x" : 214,
      "y" : 2422
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 270,
          "y" : 2422
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 270,
          "y" : 2422
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 138301,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 254,
          "y" : 2447
        },
        "to" : {
          "x" : 267,
          "y" : 2455
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 138300,
    "reactomeId" : 10805846,
    "displayName" : "Centrosome:p-T288-AURKA:TPX2:HMMR",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 638,
      "y" : 2355
    },
    "minX" : 522,
    "maxX" : 691,
    "minY" : 2319,
    "maxY" : 2385,
    "prop" : {
      "x" : 592,
      "y" : 2325,
      "width" : 93,
      "height" : 60
    },
    "textPosition" : {
      "x" : 594,
      "y" : 2322
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 685,
          "y" : 2325
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 685,
          "y" : 2325
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 138299,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 589,
          "y" : 2357
        },
        "to" : {
          "x" : 522,
          "y" : 2360
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 582,
          "y" : 2361
        },
        "b" : {
          "x" : 589,
          "y" : 2357
        },
        "c" : {
          "x" : 582,
          "y" : 2353
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 582,
          "y" : 2353
        }
      }
    } ]
  }, {
    "id" : 138306,
    "reactomeId" : 113592,
    "displayName" : "ATP",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 226,
      "y" : 2578
    },
    "minX" : 208,
    "maxX" : 262,
    "minY" : 2565,
    "maxY" : 2593,
    "prop" : {
      "x" : 208,
      "y" : 2566,
      "width" : 36,
      "height" : 24
    },
    "textPosition" : {
      "x" : 210,
      "y" : 2567
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 239,
          "y" : 2571
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 239,
          "y" : 2571
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 138305,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 247,
          "y" : 2585
        },
        "to" : {
          "x" : 262,
          "y" : 2593
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 138307,
    "reactomeId" : 29370,
    "displayName" : "ADP",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 220,
      "y" : 2690
    },
    "minX" : 200,
    "maxX" : 265,
    "minY" : 2659,
    "maxY" : 2703,
    "prop" : {
      "x" : 200,
      "y" : 2677,
      "width" : 41,
      "height" : 26
    },
    "textPosition" : {
      "x" : 204,
      "y" : 2679
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 236,
          "y" : 2682
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 236,
          "y" : 2682
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 138305,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 238,
          "y" : 2674
        },
        "to" : {
          "x" : 265,
          "y" : 2659
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 242,
          "y" : 2667
        },
        "b" : {
          "x" : 238,
          "y" : 2674
        },
        "c" : {
          "x" : 246,
          "y" : 2674
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 246,
          "y" : 2674
        }
      }
    } ]
  }, {
    "id" : 138304,
    "reactomeId" : 10805855,
    "displayName" : "AURKA:PHLDA1",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 266,
      "y" : 2515
    },
    "minX" : 232,
    "maxX" : 306,
    "minY" : 2490,
    "maxY" : 2613,
    "prop" : {
      "x" : 232,
      "y" : 2496,
      "width" : 68,
      "height" : 39
    },
    "textPosition" : {
      "x" : 238,
      "y" : 2500
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 300,
          "y" : 2496
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 300,
          "y" : 2496
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 138301,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 138305,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 265,
          "y" : 2538
        },
        "to" : {
          "x" : 262,
          "y" : 2593
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 138305,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 270,
          "y" : 2538
        },
        "to" : {
          "x" : 288,
          "y" : 2608
        }
      }, {
        "from" : {
          "x" : 288,
          "y" : 2608
        },
        "to" : {
          "x" : 274,
          "y" : 2609
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 270,
          "y" : 2609
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 270,
          "y" : 2609
        }
      }
    } ]
  }, {
    "id" : 138310,
    "reactomeId" : 10805865,
    "displayName" : "SKP1:CUL1:RBX1:FBXL7",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 127,
      "y" : 2281
    },
    "minX" : 53,
    "maxX" : 188,
    "minY" : 2258,
    "maxY" : 2562,
    "prop" : {
      "x" : 80,
      "y" : 2264,
      "width" : 95,
      "height" : 35
    },
    "textPosition" : {
      "x" : 88,
      "y" : 2264
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 175,
          "y" : 2264
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 175,
          "y" : 2264
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 138309,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 138,
          "y" : 2302
        },
        "to" : {
          "x" : 188,
          "y" : 2378
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 138315,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 113,
          "y" : 2302
        },
        "to" : {
          "x" : 66,
          "y" : 2363
        }
      }, {
        "from" : {
          "x" : 66,
          "y" : 2363
        },
        "to" : {
          "x" : 53,
          "y" : 2562
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 112,
          "y" : 2310
        },
        "b" : {
          "x" : 113,
          "y" : 2302
        },
        "c" : {
          "x" : 106,
          "y" : 2305
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 106,
          "y" : 2305
        }
      }
    } ]
  }, {
    "id" : 138311,
    "reactomeId" : 10805867,
    "displayName" : "SCF-FBXL7:AURKA",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 148,
      "y" : 2451
    },
    "minX" : 104,
    "maxX" : 199,
    "minY" : 2426,
    "maxY" : 2528,
    "prop" : {
      "x" : 104,
      "y" : 2432,
      "width" : 89,
      "height" : 39
    },
    "textPosition" : {
      "x" : 111,
      "y" : 2436
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 193,
          "y" : 2432
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 193,
          "y" : 2432
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 138309,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 138312,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 150,
          "y" : 2474
        },
        "to" : {
          "x" : 155,
          "y" : 2504
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 138312,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 163,
          "y" : 2474
        },
        "to" : {
          "x" : 185,
          "y" : 2498
        }
      }, {
        "from" : {
          "x" : 185,
          "y" : 2498
        },
        "to" : {
          "x" : 168,
          "y" : 2521
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 165,
          "y" : 2524
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 165,
          "y" : 2524
        }
      }
    } ]
  }, {
    "id" : 138308,
    "reactomeId" : 10805860,
    "displayName" : "phospho-PHLDA1",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 315,
      "y" : 2692
    },
    "minX" : 263,
    "maxX" : 373,
    "minY" : 2659,
    "maxY" : 2705,
    "prop" : {
      "x" : 263,
      "y" : 2679,
      "width" : 104,
      "height" : 26
    },
    "textPosition" : {
      "x" : 281,
      "y" : 2675
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 367,
          "y" : 2679
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 367,
          "y" : 2679
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 138305,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 295,
          "y" : 2676
        },
        "to" : {
          "x" : 265,
          "y" : 2659
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 287,
          "y" : 2676
        },
        "b" : {
          "x" : 295,
          "y" : 2676
        },
        "c" : {
          "x" : 291,
          "y" : 2669
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 291,
          "y" : 2669
        }
      }
    } ]
  }, {
    "id" : 138314,
    "reactomeId" : 10805972,
    "displayName" : "SCF-FBXL7:PolyUb-AURKA",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 154,
      "y" : 2624
    },
    "minX" : 101,
    "maxX" : 214,
    "minY" : 2598,
    "maxY" : 2644,
    "prop" : {
      "x" : 101,
      "y" : 2604,
      "width" : 107,
      "height" : 40
    },
    "textPosition" : {
      "x" : 107,
      "y" : 2609
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 208,
          "y" : 2604
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 208,
          "y" : 2604
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 138315,
      "type" : "INPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 138312,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 138313,
    "reactomeId" : 10732743,
    "displayName" : "Ub",
    "schemaClass" : "DefinedSet",
    "renderableClass" : "EntitySet",
    "position" : {
      "x" : 111,
      "y" : 2544
    },
    "minX" : 53,
    "maxX" : 155,
    "minY" : 2504,
    "maxY" : 2562,
    "prop" : {
      "x" : 93,
      "y" : 2529,
      "width" : 37,
      "height" : 31
    },
    "textPosition" : {
      "x" : 99,
      "y" : 2534
    },
    "connectors" : [ {
      "edgeId" : 138315,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 87,
          "y" : 2549
        },
        "to" : {
          "x" : 53,
          "y" : 2562
        }
      } ],
      "stoichiometry" : {
        "value" : 3,
        "shape" : {
          "a" : {
            "x" : 64,
            "y" : 2549
          },
          "b" : {
            "x" : 76,
            "y" : 2561
          },
          "type" : "BOX",
          "empty" : true,
          "centre" : {
            "x" : 70,
            "y" : 2555
          }
        }
      },
      "endShape" : {
        "a" : {
          "x" : 82,
          "y" : 2555
        },
        "b" : {
          "x" : 87,
          "y" : 2549
        },
        "c" : {
          "x" : 79,
          "y" : 2548
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 79,
          "y" : 2548
        }
      }
    }, {
      "edgeId" : 138312,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 128,
          "y" : 2523
        },
        "to" : {
          "x" : 155,
          "y" : 2504
        }
      } ],
      "stoichiometry" : {
        "value" : 3,
        "shape" : {
          "a" : {
            "x" : 135,
            "y" : 2507
          },
          "b" : {
            "x" : 147,
            "y" : 2519
          },
          "type" : "BOX",
          "empty" : true,
          "centre" : {
            "x" : 141,
            "y" : 2513
          }
        }
      }
    } ]
  }, {
    "id" : 138318,
    "reactomeId" : 10805980,
    "displayName" : "FBXL7",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 415,
      "y" : 2872
    },
    "minX" : 346,
    "maxX" : 491,
    "minY" : 2847,
    "maxY" : 2891,
    "prop" : {
      "x" : 346,
      "y" : 2853,
      "width" : 139,
      "height" : 38
    },
    "textPosition" : {
      "x" : 393,
      "y" : 2861
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 485,
          "y" : 2853
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 485,
          "y" : 2853
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 138317,
      "type" : "INPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 138319,
    "reactomeId" : 10732743,
    "displayName" : "Ub",
    "schemaClass" : "DefinedSet",
    "renderableClass" : "EntitySet",
    "position" : {
      "x" : 385,
      "y" : 2944
    },
    "minX" : 356,
    "maxX" : 478,
    "minY" : 2917,
    "maxY" : 2959,
    "prop" : {
      "x" : 356,
      "y" : 2929,
      "width" : 58,
      "height" : 30
    },
    "textPosition" : {
      "x" : 372,
      "y" : 2933
    },
    "connectors" : [ {
      "edgeId" : 138317,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 3,
        "shape" : {
          "a" : {
            "x" : 466,
            "y" : 2917
          },
          "b" : {
            "x" : 478,
            "y" : 2929
          },
          "type" : "BOX",
          "empty" : true,
          "centre" : {
            "x" : 472,
            "y" : 2923
          }
        }
      }
    } ]
  }, {
    "id" : 138316,
    "reactomeId" : 10732837,
    "displayName" : "26S proteasome",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 410,
      "y" : 2740
    },
    "minX" : 143,
    "maxX" : 529,
    "minY" : 2723,
    "maxY" : 2902,
    "prop" : {
      "x" : 354,
      "y" : 2729,
      "width" : 113,
      "height" : 22
    },
    "textPosition" : {
      "x" : 354,
      "y" : 2730
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 467,
          "y" : 2729
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 467,
          "y" : 2729
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 138315,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 351,
          "y" : 2740
        },
        "to" : {
          "x" : 151,
          "y" : 2744
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 147,
          "y" : 2744
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 147,
          "y" : 2744
        }
      }
    }, {
      "edgeId" : 138317,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 470,
          "y" : 2740
        },
        "to" : {
          "x" : 528,
          "y" : 2740
        }
      }, {
        "from" : {
          "x" : 528,
          "y" : 2740
        },
        "to" : {
          "x" : 525,
          "y" : 2894
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 525,
          "y" : 2898
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 525,
          "y" : 2898
        }
      }
    } ]
  }, {
    "id" : 138322,
    "reactomeId" : 10742740,
    "displayName" : "CCNA2:CDK1",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 281,
      "y" : 1128
    },
    "minX" : 254,
    "maxX" : 314,
    "minY" : 1104,
    "maxY" : 1147,
    "prop" : {
      "x" : 254,
      "y" : 1110,
      "width" : 54,
      "height" : 37
    },
    "textPosition" : {
      "x" : 254,
      "y" : 1112
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 308,
          "y" : 1110
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 308,
          "y" : 1110
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 138320,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 138321,
    "reactomeId" : 10742728,
    "displayName" : "CCNA2",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 274,
      "y" : 1187
    },
    "minX" : 209,
    "maxX" : 305,
    "minY" : 1167,
    "maxY" : 1201,
    "prop" : {
      "x" : 249,
      "y" : 1173,
      "width" : 50,
      "height" : 28
    },
    "textPosition" : {
      "x" : 249,
      "y" : 1176
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 299,
          "y" : 1173
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 299,
          "y" : 1173
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 138320,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 246,
          "y" : 1187
        },
        "to" : {
          "x" : 209,
          "y" : 1189
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 138327,
    "reactomeId" : 29358,
    "displayName" : "ATP",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 1424,
      "y" : 832
    },
    "minX" : 1368,
    "maxX" : 1443,
    "minY" : 820,
    "maxY" : 844,
    "prop" : {
      "x" : 1407,
      "y" : 821,
      "width" : 35,
      "height" : 23
    },
    "textPosition" : {
      "x" : 1409,
      "y" : 822
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1437,
          "y" : 826
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1437,
          "y" : 826
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 138326,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1404,
          "y" : 833
        },
        "to" : {
          "x" : 1368,
          "y" : 837
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 138324,
    "reactomeId" : 10742732,
    "displayName" : "CCNA1",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 108,
      "y" : 1238
    },
    "minX" : 83,
    "maxX" : 167,
    "minY" : 1185,
    "maxY" : 1251,
    "prop" : {
      "x" : 83,
      "y" : 1226,
      "width" : 51,
      "height" : 25
    },
    "textPosition" : {
      "x" : 84,
      "y" : 1228
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 134,
          "y" : 1226
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 134,
          "y" : 1226
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 138323,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 121,
          "y" : 1223
        },
        "to" : {
          "x" : 167,
          "y" : 1185
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 138325,
    "reactomeId" : 10742742,
    "displayName" : "CCNA1:CDK1",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 99,
      "y" : 1165
    },
    "minX" : 73,
    "maxX" : 131,
    "minY" : 1141,
    "maxY" : 1183,
    "prop" : {
      "x" : 73,
      "y" : 1147,
      "width" : 52,
      "height" : 36
    },
    "textPosition" : {
      "x" : 74,
      "y" : 1148
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 125,
          "y" : 1147
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 125,
          "y" : 1147
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 138323,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 138331,
    "reactomeId" : 10823218,
    "displayName" : "p-S-CCNA:p-T161-CDK1",
    "schemaClass" : "CandidateSet",
    "renderableClass" : "EntitySet",
    "position" : {
      "x" : 2108,
      "y" : 2489
    },
    "minX" : 925,
    "maxX" : 2189,
    "minY" : 2074,
    "maxY" : 2537,
    "prop" : {
      "x" : 2027,
      "y" : 2477,
      "width" : 162,
      "height" : 25
    },
    "textPosition" : {
      "x" : 2034,
      "y" : 2479
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "fgColor" : {
      "r" : 0,
      "g" : 0,
      "b" : 0
    },
    "connectors" : [ {
      "edgeId" : 138330,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 138340,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 2021,
          "y" : 2493
        },
        "to" : {
          "x" : 1245,
          "y" : 2537
        }
      }, {
        "from" : {
          "x" : 1245,
          "y" : 2537
        },
        "to" : {
          "x" : 955,
          "y" : 2080
        }
      }, {
        "from" : {
          "x" : 955,
          "y" : 2080
        },
        "to" : {
          "x" : 933,
          "y" : 2078
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 929,
          "y" : 2078
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 929,
          "y" : 2078
        }
      }
    } ]
  }, {
    "id" : 138328,
    "reactomeId" : 10823205,
    "displayName" : "p-S-CCNA:p-T161-CDK1",
    "schemaClass" : "CandidateSet",
    "renderableClass" : "EntitySet",
    "position" : {
      "x" : 1384,
      "y" : 669
    },
    "minX" : 1212,
    "maxX" : 1892,
    "minY" : 463,
    "maxY" : 961,
    "prop" : {
      "x" : 1302,
      "y" : 656,
      "width" : 165,
      "height" : 27
    },
    "textPosition" : {
      "x" : 1310,
      "y" : 659
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "fgColor" : {
      "r" : 0,
      "g" : 0,
      "b" : 0
    },
    "connectors" : [ {
      "edgeId" : 138326,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 1381,
          "y" : 689
        },
        "to" : {
          "x" : 1369,
          "y" : 750
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 1384,
          "y" : 697
        },
        "b" : {
          "x" : 1381,
          "y" : 689
        },
        "c" : {
          "x" : 1376,
          "y" : 695
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 1376,
          "y" : 695
        }
      }
    }, {
      "edgeId" : 138330,
      "type" : "INPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 138335,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 1473,
          "y" : 674
        },
        "to" : {
          "x" : 1805,
          "y" : 699
        }
      }, {
        "from" : {
          "x" : 1805,
          "y" : 699
        },
        "to" : {
          "x" : 1823,
          "y" : 671
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 1825,
          "y" : 667
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1825,
          "y" : 667
        }
      }
    }, {
      "edgeId" : 138332,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 1369,
          "y" : 689
        },
        "to" : {
          "x" : 1219,
          "y" : 819
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 1216,
          "y" : 822
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1216,
          "y" : 822
        }
      }
    }, {
      "edgeId" : 138341,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 1473,
          "y" : 679
        },
        "to" : {
          "x" : 1821,
          "y" : 723
        }
      }, {
        "from" : {
          "x" : 1821,
          "y" : 723
        },
        "to" : {
          "x" : 1827,
          "y" : 748
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 1827,
          "y" : 752
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1827,
          "y" : 752
        }
      }
    }, {
      "edgeId" : 138346,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 1413,
          "y" : 689
        },
        "to" : {
          "x" : 1859,
          "y" : 883
        }
      }, {
        "from" : {
          "x" : 1859,
          "y" : 883
        },
        "to" : {
          "x" : 1886,
          "y" : 953
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 1888,
          "y" : 957
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1888,
          "y" : 957
        }
      }
    }, {
      "edgeId" : 138351,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 1384,
          "y" : 650
        },
        "to" : {
          "x" : 1384,
          "y" : 622
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 1384,
          "y" : 618
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1384,
          "y" : 618
        }
      }
    }, {
      "edgeId" : 138356,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 1388,
          "y" : 650
        },
        "to" : {
          "x" : 1435,
          "y" : 530
        }
      }, {
        "from" : {
          "x" : 1435,
          "y" : 530
        },
        "to" : {
          "x" : 1634,
          "y" : 468
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 1638,
          "y" : 467
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1638,
          "y" : 467
        }
      }
    }, {
      "edgeId" : 138361,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 1390,
          "y" : 650
        },
        "to" : {
          "x" : 1441,
          "y" : 546
        }
      }, {
        "from" : {
          "x" : 1441,
          "y" : 546
        },
        "to" : {
          "x" : 1629,
          "y" : 526
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 1633,
          "y" : 525
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1633,
          "y" : 525
        }
      }
    } ]
  }, {
    "id" : 138329,
    "reactomeId" : 113582,
    "displayName" : "ADP",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 1426,
      "y" : 758
    },
    "minX" : 1369,
    "maxX" : 1445,
    "minY" : 744,
    "maxY" : 772,
    "prop" : {
      "x" : 1408,
      "y" : 745,
      "width" : 36,
      "height" : 27
    },
    "textPosition" : {
      "x" : 1409,
      "y" : 748
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1439,
          "y" : 750
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1439,
          "y" : 750
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 138326,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 1405,
          "y" : 755
        },
        "to" : {
          "x" : 1369,
          "y" : 750
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 1398,
          "y" : 758
        },
        "b" : {
          "x" : 1405,
          "y" : 755
        },
        "c" : {
          "x" : 1399,
          "y" : 750
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 1399,
          "y" : 750
        }
      }
    } ]
  }, {
    "id" : 138334,
    "reactomeId" : 113582,
    "displayName" : "ADP",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 1218,
      "y" : 649
    },
    "minX" : 1197,
    "maxX" : 1241,
    "minY" : 634,
    "maxY" : 732,
    "prop" : {
      "x" : 1197,
      "y" : 635,
      "width" : 43,
      "height" : 29
    },
    "textPosition" : {
      "x" : 1202,
      "y" : 639
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1235,
          "y" : 640
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1235,
          "y" : 640
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 138332,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 1216,
          "y" : 667
        },
        "to" : {
          "x" : 1209,
          "y" : 732
        }
      } ],
      "stoichiometry" : {
        "value" : 2,
        "shape" : {
          "a" : {
            "x" : 1206,
            "y" : 693
          },
          "b" : {
            "x" : 1218,
            "y" : 705
          },
          "type" : "BOX",
          "empty" : true,
          "centre" : {
            "x" : 1212,
            "y" : 699
          }
        }
      },
      "endShape" : {
        "a" : {
          "x" : 1219,
          "y" : 674
        },
        "b" : {
          "x" : 1216,
          "y" : 667
        },
        "c" : {
          "x" : 1211,
          "y" : 673
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 1211,
          "y" : 673
        }
      }
    } ]
  }, {
    "id" : 138333,
    "reactomeId" : 10823227,
    "displayName" : "phospho-p-T187,T190-WEE1",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 1105,
      "y" : 688
    },
    "minX" : 1037,
    "maxX" : 1209,
    "minY" : 667,
    "maxY" : 732,
    "prop" : {
      "x" : 1037,
      "y" : 673,
      "width" : 137,
      "height" : 31
    },
    "textPosition" : {
      "x" : 1048,
      "y" : 671
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1174,
          "y" : 673
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1174,
          "y" : 673
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 138332,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 1141,
          "y" : 707
        },
        "to" : {
          "x" : 1209,
          "y" : 732
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 1149,
          "y" : 706
        },
        "b" : {
          "x" : 1141,
          "y" : 707
        },
        "c" : {
          "x" : 1146,
          "y" : 713
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 1146,
          "y" : 713
        }
      }
    } ]
  }, {
    "id" : 138338,
    "reactomeId" : 29370,
    "displayName" : "ADP",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 1923,
      "y" : 683
    },
    "minX" : 1881,
    "maxX" : 1945,
    "minY" : 650,
    "maxY" : 699,
    "prop" : {
      "x" : 1903,
      "y" : 668,
      "width" : 41,
      "height" : 31
    },
    "textPosition" : {
      "x" : 1907,
      "y" : 673
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1939,
          "y" : 673
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1939,
          "y" : 673
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 138335,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 1903,
          "y" : 665
        },
        "to" : {
          "x" : 1881,
          "y" : 650
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 1895,
          "y" : 664
        },
        "b" : {
          "x" : 1903,
          "y" : 665
        },
        "c" : {
          "x" : 1900,
          "y" : 658
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 1900,
          "y" : 658
        }
      }
    } ]
  }, {
    "id" : 138339,
    "reactomeId" : 10823261,
    "displayName" : "phospho-SGO1",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 1986,
      "y" : 616
    },
    "minX" : 1881,
    "maxX" : 2032,
    "minY" : 596,
    "maxY" : 650,
    "prop" : {
      "x" : 1947,
      "y" : 602,
      "width" : 79,
      "height" : 28
    },
    "textPosition" : {
      "x" : 1953,
      "y" : 599
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 2026,
          "y" : 602
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 2026,
          "y" : 602
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 138335,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 1944,
          "y" : 628
        },
        "to" : {
          "x" : 1881,
          "y" : 650
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 1939,
          "y" : 634
        },
        "b" : {
          "x" : 1944,
          "y" : 628
        },
        "c" : {
          "x" : 1936,
          "y" : 627
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 1936,
          "y" : 627
        }
      }
    } ]
  }, {
    "id" : 138336,
    "reactomeId" : 29358,
    "displayName" : "ATP",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 1714,
      "y" : 640
    },
    "minX" : 1695,
    "maxX" : 1781,
    "minY" : 627,
    "maxY" : 652,
    "prop" : {
      "x" : 1695,
      "y" : 628,
      "width" : 39,
      "height" : 24
    },
    "textPosition" : {
      "x" : 1699,
      "y" : 629
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1729,
          "y" : 633
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1729,
          "y" : 633
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 138335,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1737,
          "y" : 638
        },
        "to" : {
          "x" : 1781,
          "y" : 634
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 138337,
    "reactomeId" : 10823258,
    "displayName" : "SGO1",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 1725,
      "y" : 594
    },
    "minX" : 1705,
    "maxX" : 1781,
    "minY" : 577,
    "maxY" : 634,
    "prop" : {
      "x" : 1705,
      "y" : 583,
      "width" : 41,
      "height" : 23
    },
    "textPosition" : {
      "x" : 1708,
      "y" : 577
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1746,
          "y" : 583
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1746,
          "y" : 583
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 138335,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1741,
          "y" : 609
        },
        "to" : {
          "x" : 1781,
          "y" : 634
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 138342,
    "reactomeId" : 10743430,
    "displayName" : "FZR1",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 1719,
      "y" : 760
    },
    "minX" : 1696,
    "maxX" : 1780,
    "minY" : 743,
    "maxY" : 772,
    "prop" : {
      "x" : 1696,
      "y" : 749,
      "width" : 47,
      "height" : 23
    },
    "textPosition" : {
      "x" : 1699,
      "y" : 750
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1743,
          "y" : 749
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1743,
          "y" : 749
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 138341,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1746,
          "y" : 760
        },
        "to" : {
          "x" : 1780,
          "y" : 761
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 138343,
    "reactomeId" : 29358,
    "displayName" : "ATP",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 1759,
      "y" : 813
    },
    "minX" : 1738,
    "maxX" : 1782,
    "minY" : 761,
    "maxY" : 826,
    "prop" : {
      "x" : 1738,
      "y" : 801,
      "width" : 43,
      "height" : 25
    },
    "textPosition" : {
      "x" : 1744,
      "y" : 803
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1776,
          "y" : 806
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1776,
          "y" : 806
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 138341,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1764,
          "y" : 798
        },
        "to" : {
          "x" : 1780,
          "y" : 761
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 138347,
    "reactomeId" : 29358,
    "displayName" : "ATP",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 1765,
      "y" : 968
    },
    "minX" : 1748,
    "maxX" : 1853,
    "minY" : 958,
    "maxY" : 977,
    "prop" : {
      "x" : 1748,
      "y" : 959,
      "width" : 34,
      "height" : 18
    },
    "textPosition" : {
      "x" : 1749,
      "y" : 958
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1777,
          "y" : 964
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1777,
          "y" : 964
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 138346,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1785,
          "y" : 967
        },
        "to" : {
          "x" : 1853,
          "y" : 967
        }
      } ],
      "stoichiometry" : {
        "value" : 4,
        "shape" : {
          "a" : {
            "x" : 1813,
            "y" : 961
          },
          "b" : {
            "x" : 1825,
            "y" : 973
          },
          "type" : "BOX",
          "empty" : true,
          "centre" : {
            "x" : 1819,
            "y" : 967
          }
        }
      }
    } ]
  }, {
    "id" : 138344,
    "reactomeId" : 10823233,
    "displayName" : "phospho-FZR1",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 1986,
      "y" : 771
    },
    "minX" : 1862,
    "maxX" : 2040,
    "minY" : 754,
    "maxY" : 783,
    "prop" : {
      "x" : 1938,
      "y" : 760,
      "width" : 96,
      "height" : 23
    },
    "textPosition" : {
      "x" : 1952,
      "y" : 754
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 2034,
          "y" : 760
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 2034,
          "y" : 760
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 138341,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 1935,
          "y" : 768
        },
        "to" : {
          "x" : 1862,
          "y" : 765
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 1928,
          "y" : 772
        },
        "b" : {
          "x" : 1935,
          "y" : 768
        },
        "c" : {
          "x" : 1928,
          "y" : 764
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 1928,
          "y" : 764
        }
      }
    } ]
  }, {
    "id" : 138345,
    "reactomeId" : 29370,
    "displayName" : "ADP",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 1916,
      "y" : 810
    },
    "minX" : 1862,
    "maxX" : 1937,
    "minY" : 765,
    "maxY" : 823,
    "prop" : {
      "x" : 1897,
      "y" : 798,
      "width" : 39,
      "height" : 25
    },
    "textPosition" : {
      "x" : 1900,
      "y" : 800
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1931,
          "y" : 803
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1931,
          "y" : 803
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 138341,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 1901,
          "y" : 795
        },
        "to" : {
          "x" : 1862,
          "y" : 765
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 1893,
          "y" : 794
        },
        "b" : {
          "x" : 1901,
          "y" : 795
        },
        "c" : {
          "x" : 1898,
          "y" : 788
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 1898,
          "y" : 788
        }
      }
    } ]
  }, {
    "id" : 138350,
    "reactomeId" : 10823245,
    "displayName" : "phospho-TICRR",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 2000,
      "y" : 1047
    },
    "minX" : 1930,
    "maxX" : 2055,
    "minY" : 970,
    "maxY" : 1081,
    "prop" : {
      "x" : 1951,
      "y" : 1014,
      "width" : 98,
      "height" : 67
    },
    "textPosition" : {
      "x" : 1966,
      "y" : 1030
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 2049,
          "y" : 1014
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 2049,
          "y" : 1014
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 138346,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 1969,
          "y" : 1011
        },
        "to" : {
          "x" : 1930,
          "y" : 970
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 1961,
          "y" : 1009
        },
        "b" : {
          "x" : 1969,
          "y" : 1011
        },
        "c" : {
          "x" : 1967,
          "y" : 1003
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 1967,
          "y" : 1003
        }
      }
    } ]
  }, {
    "id" : 138348,
    "reactomeId" : 10823239,
    "displayName" : "TICRR",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 1805,
      "y" : 1035
    },
    "minX" : 1779,
    "maxX" : 1853,
    "minY" : 967,
    "maxY" : 1046,
    "prop" : {
      "x" : 1779,
      "y" : 1024,
      "width" : 53,
      "height" : 22
    },
    "textPosition" : {
      "x" : 1784,
      "y" : 1024
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1832,
          "y" : 1024
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1832,
          "y" : 1024
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 138346,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1812,
          "y" : 1021
        },
        "to" : {
          "x" : 1853,
          "y" : 967
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 138349,
    "reactomeId" : 113582,
    "displayName" : "ADP",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 2005,
      "y" : 965
    },
    "minX" : 1930,
    "maxX" : 2023,
    "minY" : 952,
    "maxY" : 978,
    "prop" : {
      "x" : 1989,
      "y" : 953,
      "width" : 33,
      "height" : 25
    },
    "textPosition" : {
      "x" : 1989,
      "y" : 955
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 2017,
          "y" : 958
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 2017,
          "y" : 958
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 138346,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 1986,
          "y" : 966
        },
        "to" : {
          "x" : 1930,
          "y" : 970
        }
      } ],
      "stoichiometry" : {
        "value" : 4,
        "shape" : {
          "a" : {
            "x" : 1952,
            "y" : 962
          },
          "b" : {
            "x" : 1964,
            "y" : 974
          },
          "type" : "BOX",
          "empty" : true,
          "centre" : {
            "x" : 1958,
            "y" : 968
          }
        }
      },
      "endShape" : {
        "a" : {
          "x" : 1979,
          "y" : 970
        },
        "b" : {
          "x" : 1986,
          "y" : 966
        },
        "c" : {
          "x" : 1979,
          "y" : 963
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 1979,
          "y" : 963
        }
      }
    } ]
  }, {
    "id" : 138354,
    "reactomeId" : 10823254,
    "displayName" : "phospho-RNF219",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 1569,
      "y" : 598
    },
    "minX" : 1428,
    "maxX" : 1617,
    "minY" : 579,
    "maxY" : 612,
    "prop" : {
      "x" : 1527,
      "y" : 585,
      "width" : 84,
      "height" : 27
    },
    "textPosition" : {
      "x" : 1535,
      "y" : 581
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1611,
          "y" : 585
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1611,
          "y" : 585
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 138351,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 1524,
          "y" : 598
        },
        "to" : {
          "x" : 1428,
          "y" : 598
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 1517,
          "y" : 602
        },
        "b" : {
          "x" : 1524,
          "y" : 598
        },
        "c" : {
          "x" : 1517,
          "y" : 594
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 1517,
          "y" : 594
        }
      }
    } ]
  }, {
    "id" : 138355,
    "reactomeId" : 113582,
    "displayName" : "ADP",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 1537,
      "y" : 642
    },
    "minX" : 1428,
    "maxX" : 1558,
    "minY" : 598,
    "maxY" : 655,
    "prop" : {
      "x" : 1517,
      "y" : 630,
      "width" : 40,
      "height" : 25
    },
    "textPosition" : {
      "x" : 1520,
      "y" : 632
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1552,
          "y" : 635
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1552,
          "y" : 635
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 138351,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 1514,
          "y" : 633
        },
        "to" : {
          "x" : 1428,
          "y" : 598
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 1506,
          "y" : 634
        },
        "b" : {
          "x" : 1514,
          "y" : 633
        },
        "c" : {
          "x" : 1509,
          "y" : 627
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 1509,
          "y" : 627
        }
      }
    } ]
  }, {
    "id" : 138352,
    "reactomeId" : 10823251,
    "displayName" : "RNF219",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 1229,
      "y" : 595
    },
    "minX" : 1209,
    "maxX" : 1348,
    "minY" : 579,
    "maxY" : 606,
    "prop" : {
      "x" : 1209,
      "y" : 585,
      "width" : 41,
      "height" : 21
    },
    "textPosition" : {
      "x" : 1209,
      "y" : 578
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1250,
          "y" : 585
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1250,
          "y" : 585
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 138351,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1253,
          "y" : 596
        },
        "to" : {
          "x" : 1348,
          "y" : 601
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 138353,
    "reactomeId" : 29358,
    "displayName" : "ATP",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 1283,
      "y" : 625
    },
    "minX" : 1260,
    "maxX" : 1348,
    "minY" : 601,
    "maxY" : 638,
    "prop" : {
      "x" : 1260,
      "y" : 613,
      "width" : 46,
      "height" : 25
    },
    "textPosition" : {
      "x" : 1267,
      "y" : 615
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1301,
          "y" : 618
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1301,
          "y" : 618
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 138351,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1309,
          "y" : 616
        },
        "to" : {
          "x" : 1348,
          "y" : 601
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 138358,
    "reactomeId" : 29358,
    "displayName" : "ATP",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 1555,
      "y" : 410
    },
    "minX" : 1536,
    "maxX" : 1595,
    "minY" : 397,
    "maxY" : 543,
    "prop" : {
      "x" : 1536,
      "y" : 398,
      "width" : 39,
      "height" : 24
    },
    "textPosition" : {
      "x" : 1540,
      "y" : 399
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1570,
          "y" : 403
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1570,
          "y" : 403
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 138356,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1563,
          "y" : 425
        },
        "to" : {
          "x" : 1587,
          "y" : 458
        }
      } ],
      "stoichiometry" : {
        "value" : 2,
        "shape" : {
          "a" : {
            "x" : 1569,
            "y" : 435
          },
          "b" : {
            "x" : 1581,
            "y" : 447
          },
          "type" : "BOX",
          "empty" : true,
          "centre" : {
            "x" : 1575,
            "y" : 441
          }
        }
      }
    }, {
      "edgeId" : 138361,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1558,
          "y" : 425
        },
        "to" : {
          "x" : 1595,
          "y" : 543
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 138359,
    "reactomeId" : 10823267,
    "displayName" : "phospho-HJURP",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 1828,
      "y" : 464
    },
    "minX" : 1675,
    "maxX" : 1906,
    "minY" : 443,
    "maxY" : 480,
    "prop" : {
      "x" : 1756,
      "y" : 449,
      "width" : 144,
      "height" : 31
    },
    "textPosition" : {
      "x" : 1776,
      "y" : 454
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1900,
          "y" : 449
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1900,
          "y" : 449
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 138356,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 1753,
          "y" : 463
        },
        "to" : {
          "x" : 1675,
          "y" : 463
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 1746,
          "y" : 467
        },
        "b" : {
          "x" : 1753,
          "y" : 463
        },
        "c" : {
          "x" : 1746,
          "y" : 459
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 1746,
          "y" : 459
        }
      }
    } ]
  }, {
    "id" : 138357,
    "reactomeId" : 10762363,
    "displayName" : "HJURP",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 1510,
      "y" : 459
    },
    "minX" : 1486,
    "maxX" : 1587,
    "minY" : 441,
    "maxY" : 471,
    "prop" : {
      "x" : 1486,
      "y" : 447,
      "width" : 49,
      "height" : 24
    },
    "textPosition" : {
      "x" : 1488,
      "y" : 448
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1535,
          "y" : 447
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1535,
          "y" : 447
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 138356,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1538,
          "y" : 458
        },
        "to" : {
          "x" : 1587,
          "y" : 458
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 138362,
    "reactomeId" : 10762377,
    "displayName" : "MIS18BP1",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 1522,
      "y" : 563
    },
    "minX" : 1483,
    "maxX" : 1595,
    "minY" : 543,
    "maxY" : 573,
    "prop" : {
      "x" : 1483,
      "y" : 553,
      "width" : 78,
      "height" : 20
    },
    "textPosition" : {
      "x" : 1487,
      "y" : 553
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1561,
          "y" : 553
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1561,
          "y" : 553
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 138361,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1558,
          "y" : 550
        },
        "to" : {
          "x" : 1595,
          "y" : 543
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 138363,
    "reactomeId" : 10823272,
    "displayName" : "phospho-MIS18BP1",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 1831,
      "y" : 522
    },
    "minX" : 1706,
    "maxX" : 1909,
    "minY" : 504,
    "maxY" : 534,
    "prop" : {
      "x" : 1759,
      "y" : 510,
      "width" : 144,
      "height" : 24
    },
    "textPosition" : {
      "x" : 1767,
      "y" : 511
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1903,
          "y" : 510
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1903,
          "y" : 510
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 138361,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 1756,
          "y" : 516
        },
        "to" : {
          "x" : 1706,
          "y" : 512
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 1749,
          "y" : 519
        },
        "b" : {
          "x" : 1756,
          "y" : 516
        },
        "c" : {
          "x" : 1749,
          "y" : 511
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 1749,
          "y" : 511
        }
      }
    } ]
  }, {
    "id" : 138360,
    "reactomeId" : 113582,
    "displayName" : "ADP",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 1701,
      "y" : 412
    },
    "minX" : 1675,
    "maxX" : 1719,
    "minY" : 399,
    "maxY" : 512,
    "prop" : {
      "x" : 1685,
      "y" : 400,
      "width" : 33,
      "height" : 25
    },
    "textPosition" : {
      "x" : 1685,
      "y" : 402
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1713,
          "y" : 405
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1713,
          "y" : 405
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 138356,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 1694,
          "y" : 428
        },
        "to" : {
          "x" : 1675,
          "y" : 463
        }
      } ],
      "stoichiometry" : {
        "value" : 2,
        "shape" : {
          "a" : {
            "x" : 1678,
            "y" : 439
          },
          "b" : {
            "x" : 1690,
            "y" : 451
          },
          "type" : "BOX",
          "empty" : true,
          "centre" : {
            "x" : 1684,
            "y" : 445
          }
        }
      },
      "endShape" : {
        "a" : {
          "x" : 1694,
          "y" : 436
        },
        "b" : {
          "x" : 1694,
          "y" : 428
        },
        "c" : {
          "x" : 1687,
          "y" : 432
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 1687,
          "y" : 432
        }
      }
    }, {
      "edgeId" : 138361,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 1701,
          "y" : 428
        },
        "to" : {
          "x" : 1706,
          "y" : 512
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 1705,
          "y" : 435
        },
        "b" : {
          "x" : 1701,
          "y" : 428
        },
        "c" : {
          "x" : 1697,
          "y" : 435
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 1697,
          "y" : 435
        }
      }
    } ]
  }, {
    "id" : 138372,
    "reactomeId" : 10743525,
    "displayName" : "CCNB1:p-T161-CDK1",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 1494,
      "y" : 2343
    },
    "minX" : 1437,
    "maxX" : 1558,
    "minY" : 2318,
    "maxY" : 2362,
    "prop" : {
      "x" : 1437,
      "y" : 2324,
      "width" : 115,
      "height" : 38
    },
    "textPosition" : {
      "x" : 1444,
      "y" : 2327
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1552,
          "y" : 2324
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1552,
          "y" : 2324
        }
      }
    },
    "connectors" : [ ]
  }, {
    "id" : 138391,
    "reactomeId" : 10825147,
    "displayName" : "Transcriptional Regulation by TP53",
    "schemaClass" : "Pathway",
    "renderableClass" : "EncapsulatedNode",
    "position" : {
      "x" : 2102,
      "y" : 2185
    },
    "minX" : 2030,
    "maxX" : 2175,
    "minY" : 2157,
    "maxY" : 2213,
    "prop" : {
      "x" : 2030,
      "y" : 2157,
      "width" : 145,
      "height" : 56
    },
    "textPosition" : {
      "x" : 2034,
      "y" : 2163
    },
    "connectors" : [ ]
  }, {
    "id" : 138411,
    "reactomeId" : 10742693,
    "displayName" : "CCNB2",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 298,
      "y" : 1793
    },
    "minX" : 273,
    "maxX" : 329,
    "minY" : 1776,
    "maxY" : 1804,
    "prop" : {
      "x" : 273,
      "y" : 1782,
      "width" : 50,
      "height" : 22
    },
    "textPosition" : {
      "x" : 273,
      "y" : 1782
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 323,
          "y" : 1782
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 323,
          "y" : 1782
        }
      }
    },
    "connectors" : [ ]
  }, {
    "id" : 138415,
    "reactomeId" : 10742744,
    "displayName" : "CCNA:CDK1",
    "schemaClass" : "CandidateSet",
    "renderableClass" : "EntitySet",
    "position" : {
      "x" : 183,
      "y" : 1126
    },
    "minX" : 140,
    "maxX" : 227,
    "minY" : 1115,
    "maxY" : 1137,
    "prop" : {
      "x" : 140,
      "y" : 1115,
      "width" : 87,
      "height" : 22
    },
    "textPosition" : {
      "x" : 145,
      "y" : 1115
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "connectors" : [ ]
  }, {
    "id" : 138418,
    "reactomeId" : 10825109,
    "displayName" : "Mitotic G1 phase and G1/S transition",
    "schemaClass" : "Pathway",
    "renderableClass" : "EncapsulatedNode",
    "position" : {
      "x" : 1266,
      "y" : 1393
    },
    "minX" : 1171,
    "maxX" : 1361,
    "minY" : 1365,
    "maxY" : 1421,
    "prop" : {
      "x" : 1171,
      "y" : 1365,
      "width" : 190,
      "height" : 56
    },
    "textPosition" : {
      "x" : 1173,
      "y" : 1371
    },
    "connectors" : [ ]
  }, {
    "id" : 138174,
    "reactomeId" : 10742736,
    "displayName" : "CCNA:p-T14-CDK1",
    "schemaClass" : "CandidateSet",
    "renderableClass" : "EntitySet",
    "position" : {
      "x" : 232,
      "y" : 999
    },
    "minX" : 170,
    "maxX" : 295,
    "minY" : 987,
    "maxY" : 1012,
    "prop" : {
      "x" : 170,
      "y" : 987,
      "width" : 125,
      "height" : 25
    },
    "textPosition" : {
      "x" : 174,
      "y" : 989
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "connectors" : [ {
      "edgeId" : 138173,
      "type" : "INPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 138175,
    "reactomeId" : 10742714,
    "displayName" : "CCNA:p-T14-CDK1",
    "schemaClass" : "CandidateSet",
    "renderableClass" : "EntitySet",
    "position" : {
      "x" : 1053,
      "y" : 995
    },
    "minX" : 989,
    "maxX" : 1118,
    "minY" : 982,
    "maxY" : 1059,
    "prop" : {
      "x" : 989,
      "y" : 982,
      "width" : 129,
      "height" : 27
    },
    "textPosition" : {
      "x" : 995,
      "y" : 985
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "connectors" : [ {
      "edgeId" : 138173,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 138176,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1064,
          "y" : 1015
        },
        "to" : {
          "x" : 1109,
          "y" : 1059
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 138178,
    "reactomeId" : 113582,
    "displayName" : "ADP",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 1095,
      "y" : 1167
    },
    "minX" : 1075,
    "maxX" : 1116,
    "minY" : 1128,
    "maxY" : 1180,
    "prop" : {
      "x" : 1075,
      "y" : 1154,
      "width" : 40,
      "height" : 26
    },
    "textPosition" : {
      "x" : 1078,
      "y" : 1156
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1110,
          "y" : 1159
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1110,
          "y" : 1159
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 138176,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 1099,
          "y" : 1151
        },
        "to" : {
          "x" : 1109,
          "y" : 1128
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 1098,
          "y" : 1143
        },
        "b" : {
          "x" : 1099,
          "y" : 1151
        },
        "c" : {
          "x" : 1105,
          "y" : 1146
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 1105,
          "y" : 1146
        }
      }
    } ]
  }, {
    "id" : 138179,
    "reactomeId" : 10742723,
    "displayName" : "CCNA:p-T14,T161-CDK1",
    "schemaClass" : "CandidateSet",
    "renderableClass" : "EntitySet",
    "position" : {
      "x" : 1182,
      "y" : 1150
    },
    "minX" : 1109,
    "maxX" : 1243,
    "minY" : 1123,
    "maxY" : 1168,
    "prop" : {
      "x" : 1138,
      "y" : 1132,
      "width" : 88,
      "height" : 36
    },
    "textPosition" : {
      "x" : 1140,
      "y" : 1132
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "connectors" : [ {
      "edgeId" : 138176,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 1132,
          "y" : 1136
        },
        "to" : {
          "x" : 1109,
          "y" : 1128
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 1124,
          "y" : 1138
        },
        "b" : {
          "x" : 1132,
          "y" : 1136
        },
        "c" : {
          "x" : 1127,
          "y" : 1130
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 1127,
          "y" : 1130
        }
      }
    }, {
      "edgeId" : 138181,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1222,
          "y" : 1126
        },
        "to" : {
          "x" : 1243,
          "y" : 1123
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 138177,
    "reactomeId" : 29358,
    "displayName" : "ATP",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 1141,
      "y" : 1027
    },
    "minX" : 1109,
    "maxX" : 1215,
    "minY" : 1011,
    "maxY" : 1059,
    "prop" : {
      "x" : 1122,
      "y" : 1012,
      "width" : 38,
      "height" : 30
    },
    "textPosition" : {
      "x" : 1125,
      "y" : 1016
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1155,
          "y" : 1017
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1155,
          "y" : 1017
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 138176,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1126,
          "y" : 1045
        },
        "to" : {
          "x" : 1109,
          "y" : 1059
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 138332,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1163,
          "y" : 1034
        },
        "to" : {
          "x" : 1215,
          "y" : 1055
        }
      } ],
      "stoichiometry" : {
        "value" : 2,
        "shape" : {
          "a" : {
            "x" : 1183,
            "y" : 1038
          },
          "b" : {
            "x" : 1195,
            "y" : 1050
          },
          "type" : "BOX",
          "empty" : true,
          "centre" : {
            "x" : 1189,
            "y" : 1044
          }
        }
      }
    } ]
  }, {
    "id" : 138182,
    "reactomeId" : 29358,
    "displayName" : "ATP",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 1287,
      "y" : 1145
    },
    "minX" : 1243,
    "maxX" : 1307,
    "minY" : 1123,
    "maxY" : 1160,
    "prop" : {
      "x" : 1268,
      "y" : 1130,
      "width" : 38,
      "height" : 30
    },
    "textPosition" : {
      "x" : 1271,
      "y" : 1134
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1301,
          "y" : 1135
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1301,
          "y" : 1135
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 138181,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1265,
          "y" : 1135
        },
        "to" : {
          "x" : 1243,
          "y" : 1123
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 138183,
    "reactomeId" : 113582,
    "displayName" : "ADP",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 1336,
      "y" : 1027
    },
    "minX" : 1243,
    "maxX" : 1357,
    "minY" : 1011,
    "maxY" : 1055,
    "prop" : {
      "x" : 1316,
      "y" : 1012,
      "width" : 40,
      "height" : 30
    },
    "textPosition" : {
      "x" : 1319,
      "y" : 1016
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1351,
          "y" : 1017
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1351,
          "y" : 1017
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 138181,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 1313,
          "y" : 1033
        },
        "to" : {
          "x" : 1243,
          "y" : 1055
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 1308,
          "y" : 1039
        },
        "b" : {
          "x" : 1313,
          "y" : 1033
        },
        "c" : {
          "x" : 1305,
          "y" : 1031
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 1305,
          "y" : 1031
        }
      }
    } ]
  }, {
    "id" : 138180,
    "reactomeId" : 10735589,
    "displayName" : "CAK",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 1048,
      "y" : 1089
    },
    "minX" : 1031,
    "maxX" : 1101,
    "minY" : 1072,
    "maxY" : 1100,
    "prop" : {
      "x" : 1031,
      "y" : 1078,
      "width" : 34,
      "height" : 22
    },
    "textPosition" : {
      "x" : 1032,
      "y" : 1079
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1065,
          "y" : 1078
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1065,
          "y" : 1078
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 138176,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 1068,
          "y" : 1089
        },
        "to" : {
          "x" : 1093,
          "y" : 1089
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 1097,
          "y" : 1089
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1097,
          "y" : 1089
        }
      }
    } ]
  }, {
    "id" : 138187,
    "reactomeId" : 113518,
    "displayName" : "H2O",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 1444,
      "y" : 1061
    },
    "minX" : 1424,
    "maxX" : 1465,
    "minY" : 1011,
    "maxY" : 1076,
    "prop" : {
      "x" : 1424,
      "y" : 1046,
      "width" : 40,
      "height" : 30
    },
    "textPosition" : {
      "x" : 1427,
      "y" : 1050
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1459,
          "y" : 1051
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1459,
          "y" : 1051
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 138186,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1439,
          "y" : 1043
        },
        "to" : {
          "x" : 1430,
          "y" : 1011
        }
      } ],
      "stoichiometry" : {
        "value" : 2,
        "shape" : {
          "a" : {
            "x" : 1428,
            "y" : 1021
          },
          "b" : {
            "x" : 1440,
            "y" : 1033
          },
          "type" : "BOX",
          "empty" : true,
          "centre" : {
            "x" : 1434,
            "y" : 1027
          }
        }
      }
    } ],
    "trivial" : true
  }, {
    "id" : 138184,
    "reactomeId" : 10742753,
    "displayName" : "CCNA:p-T14,Y15,T161-CDK1",
    "schemaClass" : "CandidateSet",
    "renderableClass" : "EntitySet",
    "position" : {
      "x" : 1297,
      "y" : 979
    },
    "minX" : 1240,
    "maxX" : 1430,
    "minY" : 962,
    "maxY" : 1055,
    "prop" : {
      "x" : 1240,
      "y" : 962,
      "width" : 115,
      "height" : 35
    },
    "textPosition" : {
      "x" : 1242,
      "y" : 962
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "connectors" : [ {
      "edgeId" : 138181,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 1284,
          "y" : 1003
        },
        "to" : {
          "x" : 1243,
          "y" : 1055
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 1283,
          "y" : 1011
        },
        "b" : {
          "x" : 1284,
          "y" : 1003
        },
        "c" : {
          "x" : 1277,
          "y" : 1006
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 1277,
          "y" : 1006
        }
      }
    }, {
      "edgeId" : 138186,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1361,
          "y" : 992
        },
        "to" : {
          "x" : 1430,
          "y" : 1011
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 138185,
    "reactomeId" : 10733052,
    "displayName" : "WEE1",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 1344,
      "y" : 1088
    },
    "minX" : 1215,
    "maxX" : 1548,
    "minY" : 1055,
    "maxY" : 1180,
    "prop" : {
      "x" : 1318,
      "y" : 1075,
      "width" : 53,
      "height" : 27
    },
    "textPosition" : {
      "x" : 1323,
      "y" : 1078
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1371,
          "y" : 1075
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1371,
          "y" : 1075
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 138181,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 1315,
          "y" : 1088
        },
        "to" : {
          "x" : 1259,
          "y" : 1089
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 1255,
          "y" : 1089
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1255,
          "y" : 1089
        }
      }
    }, {
      "edgeId" : 138198,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1374,
          "y" : 1099
        },
        "to" : {
          "x" : 1548,
          "y" : 1180
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 138332,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1315,
          "y" : 1081
        },
        "to" : {
          "x" : 1215,
          "y" : 1055
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 138190,
    "reactomeId" : 10733064,
    "displayName" : "CDC25A",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 1447,
      "y" : 1540
    },
    "minX" : 1418,
    "maxX" : 1514,
    "minY" : 975,
    "maxY" : 1551,
    "prop" : {
      "x" : 1418,
      "y" : 1529,
      "width" : 58,
      "height" : 22
    },
    "textPosition" : {
      "x" : 1418,
      "y" : 1529
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1476,
          "y" : 1529
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1476,
          "y" : 1529
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 138186,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 1479,
          "y" : 1540
        },
        "to" : {
          "x" : 1514,
          "y" : 1541
        }
      }, {
        "from" : {
          "x" : 1514,
          "y" : 1541
        },
        "to" : {
          "x" : 1502,
          "y" : 983
        }
      }, {
        "from" : {
          "x" : 1502,
          "y" : 983
        },
        "to" : {
          "x" : 1447,
          "y" : 979
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 1443,
          "y" : 979
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1443,
          "y" : 979
        }
      }
    } ]
  }, {
    "id" : 138188,
    "reactomeId" : 113550,
    "displayName" : "Pi",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 1507,
      "y" : 912
    },
    "minX" : 1430,
    "maxX" : 1522,
    "minY" : 896,
    "maxY" : 950,
    "prop" : {
      "x" : 1494,
      "y" : 897,
      "width" : 27,
      "height" : 30
    },
    "textPosition" : {
      "x" : 1498,
      "y" : 901
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1516,
          "y" : 902
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1516,
          "y" : 902
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 138186,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 1491,
          "y" : 918
        },
        "to" : {
          "x" : 1430,
          "y" : 950
        }
      } ],
      "stoichiometry" : {
        "value" : 2,
        "shape" : {
          "a" : {
            "x" : 1454,
            "y" : 928
          },
          "b" : {
            "x" : 1466,
            "y" : 940
          },
          "type" : "BOX",
          "empty" : true,
          "centre" : {
            "x" : 1460,
            "y" : 934
          }
        }
      },
      "endShape" : {
        "a" : {
          "x" : 1487,
          "y" : 925
        },
        "b" : {
          "x" : 1491,
          "y" : 918
        },
        "c" : {
          "x" : 1483,
          "y" : 918
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 1483,
          "y" : 918
        }
      }
    } ]
  }, {
    "id" : 138189,
    "reactomeId" : 10742763,
    "displayName" : "CCNA:p-T161-CDK1",
    "schemaClass" : "CandidateSet",
    "renderableClass" : "EntitySet",
    "position" : {
      "x" : 1360,
      "y" : 904
    },
    "minX" : 1291,
    "maxX" : 1430,
    "minY" : 803,
    "maxY" : 950,
    "prop" : {
      "x" : 1291,
      "y" : 893,
      "width" : 139,
      "height" : 23
    },
    "textPosition" : {
      "x" : 1298,
      "y" : 894
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "connectors" : [ {
      "edgeId" : 138186,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 1377,
          "y" : 922
        },
        "to" : {
          "x" : 1430,
          "y" : 950
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 1385,
          "y" : 922
        },
        "b" : {
          "x" : 1377,
          "y" : 922
        },
        "c" : {
          "x" : 1381,
          "y" : 929
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 1381,
          "y" : 929
        }
      }
    }, {
      "edgeId" : 138326,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1361,
          "y" : 887
        },
        "to" : {
          "x" : 1368,
          "y" : 837
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 138326,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 1351,
          "y" : 887
        },
        "to" : {
          "x" : 1311,
          "y" : 835
        }
      }, {
        "from" : {
          "x" : 1311,
          "y" : 835
        },
        "to" : {
          "x" : 1353,
          "y" : 809
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 1357,
          "y" : 807
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1357,
          "y" : 807
        }
      }
    } ]
  }, {
    "id" : 138194,
    "reactomeId" : 10742699,
    "displayName" : "CCNB:CDK1",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 208,
      "y" : 1334
    },
    "minX" : 164,
    "maxX" : 258,
    "minY" : 1316,
    "maxY" : 1347,
    "prop" : {
      "x" : 164,
      "y" : 1322,
      "width" : 88,
      "height" : 25
    },
    "textPosition" : {
      "x" : 169,
      "y" : 1326
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 252,
          "y" : 1322
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 252,
          "y" : 1322
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 138191,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 138192,
    "reactomeId" : 10742693,
    "displayName" : "CCNB2",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 260,
      "y" : 1227
    },
    "minX" : 227,
    "maxX" : 293,
    "minY" : 1210,
    "maxY" : 1254,
    "prop" : {
      "x" : 233,
      "y" : 1216,
      "width" : 54,
      "height" : 22
    },
    "textPosition" : {
      "x" : 235,
      "y" : 1216
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 287,
          "y" : 1216
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 287,
          "y" : 1216
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 138191,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 246,
          "y" : 1244
        },
        "to" : {
          "x" : 227,
          "y" : 1254
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 138193,
    "reactomeId" : 10742697,
    "displayName" : "CDK1",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 193,
      "y" : 1228
    },
    "minX" : 167,
    "maxX" : 227,
    "minY" : 1185,
    "maxY" : 1254,
    "prop" : {
      "x" : 167,
      "y" : 1218,
      "width" : 52,
      "height" : 21
    },
    "textPosition" : {
      "x" : 173,
      "y" : 1218
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 219,
          "y" : 1218
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 219,
          "y" : 1218
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 138191,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 206,
          "y" : 1242
        },
        "to" : {
          "x" : 227,
          "y" : 1254
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 138323,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 186,
          "y" : 1215
        },
        "to" : {
          "x" : 167,
          "y" : 1185
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 138320,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 197,
          "y" : 1215
        },
        "to" : {
          "x" : 209,
          "y" : 1189
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 138199,
    "reactomeId" : 29358,
    "displayName" : "ATP",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 1545,
      "y" : 1249
    },
    "minX" : 1527,
    "maxX" : 1564,
    "minY" : 1180,
    "maxY" : 1263,
    "prop" : {
      "x" : 1527,
      "y" : 1235,
      "width" : 36,
      "height" : 28
    },
    "textPosition" : {
      "x" : 1529,
      "y" : 1238
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1558,
          "y" : 1240
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1558,
          "y" : 1240
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 138198,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1545,
          "y" : 1232
        },
        "to" : {
          "x" : 1548,
          "y" : 1180
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 138196,
    "reactomeId" : 10742767,
    "displayName" : "CDC25A",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 1664,
      "y" : 2109
    },
    "minX" : 1636,
    "maxX" : 1698,
    "minY" : 2092,
    "maxY" : 2120,
    "prop" : {
      "x" : 1636,
      "y" : 2098,
      "width" : 56,
      "height" : 22
    },
    "textPosition" : {
      "x" : 1639,
      "y" : 2092
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1692,
          "y" : 2098
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1692,
          "y" : 2098
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 138195,
      "type" : "INPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 138197,
    "reactomeId" : 10733064,
    "displayName" : "CDC25A",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 1563,
      "y" : 974
    },
    "minX" : 1531,
    "maxX" : 1601,
    "minY" : 957,
    "maxY" : 985,
    "prop" : {
      "x" : 1531,
      "y" : 963,
      "width" : 64,
      "height" : 22
    },
    "textPosition" : {
      "x" : 1534,
      "y" : 963
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1595,
          "y" : 963
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1595,
          "y" : 963
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 138195,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 138202,
    "reactomeId" : 10740531,
    "displayName" : "phospho-PLK1",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 1721,
      "y" : 1208
    },
    "minX" : 1670,
    "maxX" : 1778,
    "minY" : 1190,
    "maxY" : 1252,
    "prop" : {
      "x" : 1670,
      "y" : 1196,
      "width" : 102,
      "height" : 24
    },
    "textPosition" : {
      "x" : 1673,
      "y" : 1197
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1772,
          "y" : 1196
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1772,
          "y" : 1196
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 138198,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 1721,
          "y" : 1223
        },
        "to" : {
          "x" : 1722,
          "y" : 1244
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 1722,
          "y" : 1248
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1722,
          "y" : 1248
        }
      }
    } ]
  }, {
    "id" : 138200,
    "reactomeId" : 113582,
    "displayName" : "ADP",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 1760,
      "y" : 1314
    },
    "minX" : 1742,
    "maxX" : 1779,
    "minY" : 1260,
    "maxY" : 1326,
    "prop" : {
      "x" : 1742,
      "y" : 1302,
      "width" : 36,
      "height" : 24
    },
    "textPosition" : {
      "x" : 1743,
      "y" : 1303
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1773,
          "y" : 1307
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1773,
          "y" : 1307
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 138198,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 1757,
          "y" : 1299
        },
        "to" : {
          "x" : 1747,
          "y" : 1260
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 1751,
          "y" : 1293
        },
        "b" : {
          "x" : 1757,
          "y" : 1299
        },
        "c" : {
          "x" : 1759,
          "y" : 1291
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 1759,
          "y" : 1291
        }
      }
    } ]
  }, {
    "id" : 138201,
    "reactomeId" : 10740548,
    "displayName" : "phospho-p-S53-WEE1",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 1818,
      "y" : 1260
    },
    "minX" : 1747,
    "maxX" : 1866,
    "minY" : 1234,
    "maxY" : 1281,
    "prop" : {
      "x" : 1776,
      "y" : 1240,
      "width" : 84,
      "height" : 41
    },
    "textPosition" : {
      "x" : 1778,
      "y" : 1243
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1860,
          "y" : 1240
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1860,
          "y" : 1240
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 138198,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 1773,
          "y" : 1260
        },
        "to" : {
          "x" : 1747,
          "y" : 1260
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 1766,
          "y" : 1264
        },
        "b" : {
          "x" : 1773,
          "y" : 1260
        },
        "c" : {
          "x" : 1766,
          "y" : 1256
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 1766,
          "y" : 1256
        }
      }
    } ]
  }, {
    "id" : 138206,
    "reactomeId" : 10754859,
    "displayName" : "Centrosomes containing recruited CDK11p58",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 532,
      "y" : 2437
    },
    "minX" : 470,
    "maxX" : 600,
    "minY" : 2406,
    "maxY" : 2462,
    "prop" : {
      "x" : 470,
      "y" : 2412,
      "width" : 124,
      "height" : 50
    },
    "textPosition" : {
      "x" : 484,
      "y" : 2399
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 594,
          "y" : 2412
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 594,
          "y" : 2412
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 138203,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 138204,
    "reactomeId" : 10754854,
    "displayName" : "CDK11p58",
    "schemaClass" : "CandidateSet",
    "renderableClass" : "EntitySet",
    "position" : {
      "x" : 708,
      "y" : 2431
    },
    "minX" : 646,
    "maxX" : 790,
    "minY" : 2413,
    "maxY" : 2453,
    "prop" : {
      "x" : 670,
      "y" : 2418,
      "width" : 76,
      "height" : 27
    },
    "textPosition" : {
      "x" : 672,
      "y" : 2421
    },
    "connectors" : [ {
      "edgeId" : 138203,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 664,
          "y" : 2444
        },
        "to" : {
          "x" : 646,
          "y" : 2453
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 138207,
      "type" : "ACTIVATOR",
      "segments" : [ {
        "from" : {
          "x" : 752,
          "y" : 2423
        },
        "to" : {
          "x" : 790,
          "y" : 2416
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 784,
          "y" : 2421
        },
        "b" : {
          "x" : 790,
          "y" : 2416
        },
        "c" : {
          "x" : 782,
          "y" : 2413
        },
        "type" : "ARROW",
        "empty" : true,
        "centre" : {
          "x" : 782,
          "y" : 2413
        }
      }
    } ]
  }, {
    "id" : 138205,
    "reactomeId" : 10754781,
    "displayName" : "centrosome",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 664,
      "y" : 2505
    },
    "minX" : 494,
    "maxX" : 848,
    "minY" : 2435,
    "maxY" : 2531,
    "prop" : {
      "x" : 622,
      "y" : 2494,
      "width" : 84,
      "height" : 22
    },
    "textPosition" : {
      "x" : 622,
      "y" : 2495
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 706,
          "y" : 2494
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 706,
          "y" : 2494
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 138203,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 660,
          "y" : 2491
        },
        "to" : {
          "x" : 646,
          "y" : 2453
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 138207,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 688,
          "y" : 2491
        },
        "to" : {
          "x" : 819,
          "y" : 2435
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 138210,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 619,
          "y" : 2511
        },
        "to" : {
          "x" : 494,
          "y" : 2531
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 138218,
      "type" : "INPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 138221,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 709,
          "y" : 2510
        },
        "to" : {
          "x" : 848,
          "y" : 2530
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 138211,
    "reactomeId" : 10754834,
    "displayName" : "gamma-tubulin complex",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 449,
      "y" : 2502
    },
    "minX" : 396,
    "maxX" : 508,
    "minY" : 2478,
    "maxY" : 2531,
    "prop" : {
      "x" : 396,
      "y" : 2484,
      "width" : 106,
      "height" : 36
    },
    "textPosition" : {
      "x" : 396,
      "y" : 2485
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 502,
          "y" : 2484
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 502,
          "y" : 2484
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 138210,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 476,
          "y" : 2523
        },
        "to" : {
          "x" : 494,
          "y" : 2531
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 138208,
    "reactomeId" : 10740263,
    "displayName" : "PLK1",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 878,
      "y" : 2341
    },
    "minX" : 772,
    "maxX" : 903,
    "minY" : 2193,
    "maxY" : 2435,
    "prop" : {
      "x" : 860,
      "y" : 2330,
      "width" : 37,
      "height" : 22
    },
    "textPosition" : {
      "x" : 860,
      "y" : 2330
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 897,
          "y" : 2330
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 897,
          "y" : 2330
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 138253,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 870,
          "y" : 2327
        },
        "to" : {
          "x" : 772,
          "y" : 2193
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 138207,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 871,
          "y" : 2355
        },
        "to" : {
          "x" : 819,
          "y" : 2435
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 138209,
    "reactomeId" : 10754846,
    "displayName" : "Centrosome associated  Plk1",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 761,
      "y" : 2359
    },
    "minX" : 717,
    "maxX" : 812,
    "minY" : 2330,
    "maxY" : 2382,
    "prop" : {
      "x" : 717,
      "y" : 2336,
      "width" : 89,
      "height" : 46
    },
    "textPosition" : {
      "x" : 717,
      "y" : 2333
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 806,
          "y" : 2336
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 806,
          "y" : 2336
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 138207,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 138214,
    "reactomeId" : 29358,
    "displayName" : "ATP",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 648,
      "y" : 704
    },
    "minX" : 627,
    "maxX" : 732,
    "minY" : 668,
    "maxY" : 716,
    "prop" : {
      "x" : 627,
      "y" : 693,
      "width" : 43,
      "height" : 23
    },
    "textPosition" : {
      "x" : 633,
      "y" : 694
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 665,
          "y" : 698
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 665,
          "y" : 698
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 138213,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 673,
          "y" : 694
        },
        "to" : {
          "x" : 732,
          "y" : 668
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 138215,
    "reactomeId" : 10744995,
    "displayName" : "CCNA:p-T160-CDK2:E2F1/E2F3",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 645,
      "y" : 651
    },
    "minX" : 585,
    "maxX" : 770,
    "minY" : 625,
    "maxY" : 671,
    "prop" : {
      "x" : 585,
      "y" : 631,
      "width" : 120,
      "height" : 40
    },
    "textPosition" : {
      "x" : 590,
      "y" : 636
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 705,
          "y" : 631
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 705,
          "y" : 631
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 138213,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 708,
          "y" : 662
        },
        "to" : {
          "x" : 732,
          "y" : 668
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 138213,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 708,
          "y" : 640
        },
        "to" : {
          "x" : 765,
          "y" : 629
        }
      }, {
        "from" : {
          "x" : 765,
          "y" : 629
        },
        "to" : {
          "x" : 766,
          "y" : 654
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 766,
          "y" : 658
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 766,
          "y" : 658
        }
      }
    }, {
      "edgeId" : 138226,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 138212,
    "reactomeId" : 10754836,
    "displayName" : "Mature centrosomes enriched in gamma-TURC complexes",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 478,
      "y" : 2627
    },
    "minX" : 415,
    "maxX" : 548,
    "minY" : 2594,
    "maxY" : 2655,
    "prop" : {
      "x" : 415,
      "y" : 2600,
      "width" : 127,
      "height" : 55
    },
    "textPosition" : {
      "x" : 431,
      "y" : 2578
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 542,
          "y" : 2600
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 542,
          "y" : 2600
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 138210,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 138219,
    "reactomeId" : 10754641,
    "displayName" : "CEP250",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 709,
      "y" : 2631
    },
    "minX" : 660,
    "maxX" : 745,
    "minY" : 2582,
    "maxY" : 2646,
    "prop" : {
      "x" : 679,
      "y" : 2617,
      "width" : 60,
      "height" : 29
    },
    "textPosition" : {
      "x" : 681,
      "y" : 2621
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 739,
          "y" : 2617
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 739,
          "y" : 2617
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 138218,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 694,
          "y" : 2614
        },
        "to" : {
          "x" : 660,
          "y" : 2582
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 686,
          "y" : 2612
        },
        "b" : {
          "x" : 694,
          "y" : 2614
        },
        "c" : {
          "x" : 692,
          "y" : 2606
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 692,
          "y" : 2606
        }
      }
    } ]
  }, {
    "id" : 138216,
    "reactomeId" : 10745015,
    "displayName" : "CCNA:p-T160-CDK2:p-E2F1/p-E2F3",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 859,
      "y" : 636
    },
    "minX" : 789,
    "maxX" : 935,
    "minY" : 612,
    "maxY" : 668,
    "prop" : {
      "x" : 789,
      "y" : 618,
      "width" : 140,
      "height" : 37
    },
    "textPosition" : {
      "x" : 789,
      "y" : 620
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 929,
          "y" : 618
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 929,
          "y" : 618
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 138213,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 824,
          "y" : 658
        },
        "to" : {
          "x" : 800,
          "y" : 668
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 819,
          "y" : 664
        },
        "b" : {
          "x" : 824,
          "y" : 658
        },
        "c" : {
          "x" : 816,
          "y" : 657
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 816,
          "y" : 657
        }
      }
    } ]
  }, {
    "id" : 138217,
    "reactomeId" : 113582,
    "displayName" : "ADP",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 844,
      "y" : 701
    },
    "minX" : 800,
    "maxX" : 868,
    "minY" : 668,
    "maxY" : 712,
    "prop" : {
      "x" : 822,
      "y" : 690,
      "width" : 45,
      "height" : 22
    },
    "textPosition" : {
      "x" : 828,
      "y" : 690
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 862,
          "y" : 695
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 862,
          "y" : 695
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 138213,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 829,
          "y" : 687
        },
        "to" : {
          "x" : 800,
          "y" : 668
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 821,
          "y" : 687
        },
        "b" : {
          "x" : 829,
          "y" : 687
        },
        "c" : {
          "x" : 825,
          "y" : 680
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 825,
          "y" : 680
        }
      }
    } ]
  }, {
    "id" : 138222,
    "reactomeId" : 113592,
    "displayName" : "ATP",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 828,
      "y" : 2563
    },
    "minX" : 809,
    "maxX" : 848,
    "minY" : 2530,
    "maxY" : 2578,
    "prop" : {
      "x" : 809,
      "y" : 2548,
      "width" : 38,
      "height" : 30
    },
    "textPosition" : {
      "x" : 812,
      "y" : 2552
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 842,
          "y" : 2553
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 842,
          "y" : 2553
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 138221,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 837,
          "y" : 2545
        },
        "to" : {
          "x" : 848,
          "y" : 2530
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 138223,
    "reactomeId" : 10754785,
    "displayName" : "centrosome containing phosphorylated Nlp",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 963,
      "y" : 2465
    },
    "minX" : 895,
    "maxX" : 1027,
    "minY" : 2426,
    "maxY" : 2531,
    "prop" : {
      "x" : 906,
      "y" : 2432,
      "width" : 115,
      "height" : 67
    },
    "textPosition" : {
      "x" : 908,
      "y" : 2436
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1021,
          "y" : 2432
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1021,
          "y" : 2432
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 138221,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 928,
          "y" : 2502
        },
        "to" : {
          "x" : 895,
          "y" : 2531
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 925,
          "y" : 2510
        },
        "b" : {
          "x" : 928,
          "y" : 2502
        },
        "c" : {
          "x" : 920,
          "y" : 2504
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 920,
          "y" : 2504
        }
      }
    } ]
  }, {
    "id" : 138220,
    "reactomeId" : 10754840,
    "displayName" : "cNAP-1 depleted centrosome",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 608,
      "y" : 2634
    },
    "minX" : 557,
    "maxX" : 665,
    "minY" : 2582,
    "maxY" : 2660,
    "prop" : {
      "x" : 557,
      "y" : 2609,
      "width" : 102,
      "height" : 51
    },
    "textPosition" : {
      "x" : 566,
      "y" : 2611
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 659,
          "y" : 2609
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 659,
          "y" : 2609
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 138218,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 633,
          "y" : 2606
        },
        "to" : {
          "x" : 660,
          "y" : 2582
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 636,
          "y" : 2598
        },
        "b" : {
          "x" : 633,
          "y" : 2606
        },
        "c" : {
          "x" : 641,
          "y" : 2604
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 641,
          "y" : 2604
        }
      }
    } ]
  }, {
    "id" : 138227,
    "reactomeId" : 10744993,
    "displayName" : "E2F1/E2F3",
    "schemaClass" : "DefinedSet",
    "renderableClass" : "EntitySet",
    "position" : {
      "x" : 442,
      "y" : 607
    },
    "minX" : 404,
    "maxX" : 504,
    "minY" : 594,
    "maxY" : 654,
    "prop" : {
      "x" : 404,
      "y" : 594,
      "width" : 77,
      "height" : 27
    },
    "textPosition" : {
      "x" : 405,
      "y" : 597
    },
    "connectors" : [ {
      "edgeId" : 138226,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 459,
          "y" : 627
        },
        "to" : {
          "x" : 504,
          "y" : 654
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 138224,
    "reactomeId" : 29370,
    "displayName" : "ADP",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 917,
      "y" : 2565
    },
    "minX" : 895,
    "maxX" : 938,
    "minY" : 2531,
    "maxY" : 2580,
    "prop" : {
      "x" : 897,
      "y" : 2550,
      "width" : 40,
      "height" : 30
    },
    "textPosition" : {
      "x" : 900,
      "y" : 2554
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 932,
          "y" : 2555
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 932,
          "y" : 2555
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 138221,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 907,
          "y" : 2547
        },
        "to" : {
          "x" : 895,
          "y" : 2531
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 900,
          "y" : 2544
        },
        "b" : {
          "x" : 907,
          "y" : 2547
        },
        "c" : {
          "x" : 906,
          "y" : 2539
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 906,
          "y" : 2539
        }
      }
    } ]
  }, {
    "id" : 138225,
    "reactomeId" : 10740542,
    "displayName" : "phospho-PLK1",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 427,
      "y" : 2177
    },
    "minX" : 177,
    "maxX" : 1126,
    "minY" : 1907,
    "maxY" : 2523,
    "prop" : {
      "x" : 376,
      "y" : 2162,
      "width" : 103,
      "height" : 31
    },
    "textPosition" : {
      "x" : 379,
      "y" : 2167
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 479,
          "y" : 2162
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 479,
          "y" : 2162
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 138243,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 420,
          "y" : 2159
        },
        "to" : {
          "x" : 397,
          "y" : 2107
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 414,
          "y" : 2154
        },
        "b" : {
          "x" : 420,
          "y" : 2159
        },
        "c" : {
          "x" : 421,
          "y" : 2151
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 421,
          "y" : 2151
        }
      }
    }, {
      "edgeId" : 138247,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 373,
          "y" : 2177
        },
        "to" : {
          "x" : 183,
          "y" : 2180
        }
      }, {
        "from" : {
          "x" : 183,
          "y" : 2180
        },
        "to" : {
          "x" : 182,
          "y" : 2167
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 181,
          "y" : 2163
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 181,
          "y" : 2163
        }
      }
    }, {
      "edgeId" : 138257,
      "type" : "INPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 138281,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 482,
          "y" : 2163
        },
        "to" : {
          "x" : 618,
          "y" : 2127
        }
      }, {
        "from" : {
          "x" : 618,
          "y" : 2127
        },
        "to" : {
          "x" : 776,
          "y" : 1983
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 138284,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 471,
          "y" : 2159
        },
        "to" : {
          "x" : 606,
          "y" : 2115
        }
      }, {
        "from" : {
          "x" : 606,
          "y" : 2115
        },
        "to" : {
          "x" : 739,
          "y" : 1909
        }
      }, {
        "from" : {
          "x" : 739,
          "y" : 1909
        },
        "to" : {
          "x" : 1105,
          "y" : 1907
        }
      }, {
        "from" : {
          "x" : 1105,
          "y" : 1907
        },
        "to" : {
          "x" : 1126,
          "y" : 1939
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 476,
          "y" : 2153
        },
        "b" : {
          "x" : 471,
          "y" : 2159
        },
        "c" : {
          "x" : 479,
          "y" : 2161
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 479,
          "y" : 2161
        }
      }
    }, {
      "edgeId" : 138221,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 482,
          "y" : 2183
        },
        "to" : {
          "x" : 707,
          "y" : 2210
        }
      }, {
        "from" : {
          "x" : 707,
          "y" : 2210
        },
        "to" : {
          "x" : 805,
          "y" : 2276
        }
      }, {
        "from" : {
          "x" : 805,
          "y" : 2276
        },
        "to" : {
          "x" : 867,
          "y" : 2516
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 868,
          "y" : 2519
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 868,
          "y" : 2519
        }
      }
    } ]
  }, {
    "id" : 138230,
    "reactomeId" : 10782533,
    "displayName" : "Centrosome:AURKA",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 233,
      "y" : 2278
    },
    "minX" : 192,
    "maxX" : 301,
    "minY" : 2255,
    "maxY" : 2327,
    "prop" : {
      "x" : 192,
      "y" : 2261,
      "width" : 83,
      "height" : 35
    },
    "textPosition" : {
      "x" : 195,
      "y" : 2261
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 275,
          "y" : 2261
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 275,
          "y" : 2261
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 138295,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 248,
          "y" : 2299
        },
        "to" : {
          "x" : 275,
          "y" : 2327
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 138229,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 278,
          "y" : 2278
        },
        "to" : {
          "x" : 301,
          "y" : 2278
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 138231,
    "reactomeId" : 10769224,
    "displayName" : "WTIP",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 240,
      "y" : 2232
    },
    "minX" : 218,
    "maxX" : 301,
    "minY" : 2215,
    "maxY" : 2278,
    "prop" : {
      "x" : 218,
      "y" : 2221,
      "width" : 44,
      "height" : 22
    },
    "textPosition" : {
      "x" : 221,
      "y" : 2221
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 262,
          "y" : 2221
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 262,
          "y" : 2221
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 138229,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 254,
          "y" : 2246
        },
        "to" : {
          "x" : 301,
          "y" : 2278
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 138228,
    "reactomeId" : 10732704,
    "displayName" : "CCNA:p-T160-CDK2",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 453,
      "y" : 708
    },
    "minX" : 385,
    "maxX" : 528,
    "minY" : 654,
    "maxY" : 720,
    "prop" : {
      "x" : 385,
      "y" : 697,
      "width" : 137,
      "height" : 23
    },
    "textPosition" : {
      "x" : 391,
      "y" : 699
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 522,
          "y" : 697
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 522,
          "y" : 697
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 138226,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 463,
          "y" : 694
        },
        "to" : {
          "x" : 504,
          "y" : 654
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 138234,
    "reactomeId" : 113592,
    "displayName" : "ATP",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 455,
      "y" : 2321
    },
    "minX" : 435,
    "maxX" : 476,
    "minY" : 2277,
    "maxY" : 2359,
    "prop" : {
      "x" : 435,
      "y" : 2309,
      "width" : 40,
      "height" : 25
    },
    "textPosition" : {
      "x" : 439,
      "y" : 2311
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 470,
          "y" : 2314
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 470,
          "y" : 2314
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 138299,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 455,
          "y" : 2337
        },
        "to" : {
          "x" : 455,
          "y" : 2359
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 138233,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 458,
          "y" : 2306
        },
        "to" : {
          "x" : 468,
          "y" : 2277
        }
      } ],
      "stoichiometry" : {
        "value" : 2,
        "shape" : {
          "a" : {
            "x" : 457,
            "y" : 2285
          },
          "b" : {
            "x" : 469,
            "y" : 2297
          },
          "type" : "BOX",
          "empty" : true,
          "centre" : {
            "x" : 463,
            "y" : 2291
          }
        }
      }
    } ]
  }, {
    "id" : 138235,
    "reactomeId" : 10782540,
    "displayName" : "Centrosome:p-T288-AURKA",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 643,
      "y" : 2267
    },
    "minX" : 526,
    "maxX" : 772,
    "minY" : 2119,
    "maxY" : 2292,
    "prop" : {
      "x" : 602,
      "y" : 2243,
      "width" : 83,
      "height" : 49
    },
    "textPosition" : {
      "x" : 605,
      "y" : 2243
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 685,
          "y" : 2243
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 685,
          "y" : 2243
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 138253,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 685,
          "y" : 2240
        },
        "to" : {
          "x" : 772,
          "y" : 2193
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 138233,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 599,
          "y" : 2270
        },
        "to" : {
          "x" : 526,
          "y" : 2277
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 592,
          "y" : 2275
        },
        "b" : {
          "x" : 599,
          "y" : 2270
        },
        "c" : {
          "x" : 592,
          "y" : 2267
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 592,
          "y" : 2267
        }
      }
    }, {
      "edgeId" : 138238,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 644,
          "y" : 2240
        },
        "to" : {
          "x" : 654,
          "y" : 2119
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 641,
          "y" : 2233
        },
        "b" : {
          "x" : 644,
          "y" : 2240
        },
        "c" : {
          "x" : 649,
          "y" : 2233
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 649,
          "y" : 2233
        }
      }
    } ]
  }, {
    "id" : 138232,
    "reactomeId" : 10782535,
    "displayName" : "Centrosome:AURKA:AJUBA",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 394,
      "y" : 2278
    },
    "minX" : 353,
    "maxX" : 492,
    "minY" : 2242,
    "maxY" : 2302,
    "prop" : {
      "x" : 353,
      "y" : 2254,
      "width" : 82,
      "height" : 48
    },
    "textPosition" : {
      "x" : 356,
      "y" : 2253
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 435,
          "y" : 2254
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 435,
          "y" : 2254
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 138229,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 138233,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 438,
          "y" : 2277
        },
        "to" : {
          "x" : 468,
          "y" : 2277
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 138233,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 438,
          "y" : 2258
        },
        "to" : {
          "x" : 471,
          "y" : 2242
        }
      }, {
        "from" : {
          "x" : 471,
          "y" : 2242
        },
        "to" : {
          "x" : 485,
          "y" : 2265
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 488,
          "y" : 2268
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 488,
          "y" : 2268
        }
      }
    } ]
  }, {
    "id" : 138239,
    "reactomeId" : 113592,
    "displayName" : "ATP",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 719,
      "y" : 2166
    },
    "minX" : 699,
    "maxX" : 739,
    "minY" : 2141,
    "maxY" : 2177,
    "prop" : {
      "x" : 700,
      "y" : 2155,
      "width" : 38,
      "height" : 22
    },
    "textPosition" : {
      "x" : 703,
      "y" : 2155
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 733,
          "y" : 2160
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 733,
          "y" : 2160
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 138238,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 710,
          "y" : 2152
        },
        "to" : {
          "x" : 699,
          "y" : 2141
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 138236,
    "reactomeId" : 10782543,
    "displayName" : "phospho-WTIP",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 561,
      "y" : 2215
    },
    "minX" : 520,
    "maxX" : 609,
    "minY" : 2196,
    "maxY" : 2277,
    "prop" : {
      "x" : 520,
      "y" : 2202,
      "width" : 83,
      "height" : 26
    },
    "textPosition" : {
      "x" : 528,
      "y" : 2198
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 603,
          "y" : 2202
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 603,
          "y" : 2202
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 138233,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 553,
          "y" : 2231
        },
        "to" : {
          "x" : 526,
          "y" : 2277
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 553,
          "y" : 2239
        },
        "b" : {
          "x" : 553,
          "y" : 2231
        },
        "c" : {
          "x" : 546,
          "y" : 2235
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 546,
          "y" : 2235
        }
      }
    } ]
  }, {
    "id" : 138237,
    "reactomeId" : 29370,
    "displayName" : "ADP",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 544,
      "y" : 2327
    },
    "minX" : 522,
    "maxX" : 565,
    "minY" : 2277,
    "maxY" : 2360,
    "prop" : {
      "x" : 524,
      "y" : 2315,
      "width" : 40,
      "height" : 24
    },
    "textPosition" : {
      "x" : 527,
      "y" : 2316
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 559,
          "y" : 2320
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 559,
          "y" : 2320
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 138299,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 536,
          "y" : 2342
        },
        "to" : {
          "x" : 522,
          "y" : 2360
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 535,
          "y" : 2350
        },
        "b" : {
          "x" : 536,
          "y" : 2342
        },
        "c" : {
          "x" : 529,
          "y" : 2345
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 529,
          "y" : 2345
        }
      }
    }, {
      "edgeId" : 138233,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 539,
          "y" : 2312
        },
        "to" : {
          "x" : 526,
          "y" : 2277
        }
      } ],
      "stoichiometry" : {
        "value" : 2,
        "shape" : {
          "a" : {
            "x" : 526,
            "y" : 2288
          },
          "b" : {
            "x" : 538,
            "y" : 2300
          },
          "type" : "BOX",
          "empty" : true,
          "centre" : {
            "x" : 532,
            "y" : 2294
          }
        }
      },
      "endShape" : {
        "a" : {
          "x" : 533,
          "y" : 2307
        },
        "b" : {
          "x" : 539,
          "y" : 2312
        },
        "c" : {
          "x" : 540,
          "y" : 2304
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 540,
          "y" : 2304
        }
      }
    } ]
  } ],
  "edges" : [ {
    "id" : 138243,
    "reactomeId" : 10783655,
    "displayName" : "PLK1 phosphorylates BORA",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 426,
      "y" : 2104
    },
    "minX" : 397,
    "maxX" : 456,
    "minY" : 2098,
    "maxY" : 2110,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 456,
        "y" : 2102
      },
      "to" : {
        "x" : 426,
        "y" : 2104
      }
    }, {
      "from" : {
        "x" : 426,
        "y" : 2104
      },
      "to" : {
        "x" : 397,
        "y" : 2107
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 420,
        "y" : 2098
      },
      "b" : {
        "x" : 432,
        "y" : 2110
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 426,
        "y" : 2104
      }
    },
    "inputs" : [ {
      "id" : 138241,
      "points" : [ {
        "x" : 545,
        "y" : 2007
      } ]
    }, {
      "id" : 138244,
      "points" : [ {
        "x" : 509,
        "y" : 2091
      } ]
    } ],
    "outputs" : [ {
      "id" : 138245,
      "points" : [ {
        "x" : 341,
        "y" : 2084
      } ]
    }, {
      "id" : 138225,
      "points" : [ {
        "x" : 420,
        "y" : 2159
      } ]
    }, {
      "id" : 138246,
      "points" : [ {
        "x" : 392,
        "y" : 2062
      } ]
    } ],
    "catalysts" : [ {
      "id" : 138241,
      "points" : [ {
        "x" : 533,
        "y" : 2007
      }, {
        "x" : 429,
        "y" : 2069
      } ]
    } ]
  }, {
    "id" : 138247,
    "reactomeId" : 10782515,
    "displayName" : "PLK1 phosphorylates OPTN",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 180,
      "y" : 2151
    },
    "minX" : 158,
    "maxX" : 201,
    "minY" : 2145,
    "maxY" : 2157,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 201,
        "y" : 2152
      },
      "to" : {
        "x" : 180,
        "y" : 2151
      }
    }, {
      "from" : {
        "x" : 180,
        "y" : 2151
      },
      "to" : {
        "x" : 158,
        "y" : 2151
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 174,
        "y" : 2145
      },
      "b" : {
        "x" : 186,
        "y" : 2157
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 180,
        "y" : 2151
      }
    },
    "inputs" : [ {
      "id" : 138248,
      "points" : [ {
        "x" : 234,
        "y" : 2152
      } ]
    }, {
      "id" : 138249,
      "points" : [ {
        "x" : 206,
        "y" : 2125
      } ]
    } ],
    "outputs" : [ {
      "id" : 138250,
      "points" : [ {
        "x" : 130,
        "y" : 2151
      } ]
    }, {
      "id" : 138251,
      "points" : [ {
        "x" : 158,
        "y" : 1857
      } ]
    }, {
      "id" : 138252,
      "points" : [ {
        "x" : 112,
        "y" : 2124
      } ]
    } ],
    "catalysts" : [ {
      "id" : 138225,
      "points" : [ {
        "x" : 373,
        "y" : 2177
      }, {
        "x" : 183,
        "y" : 2180
      } ]
    } ]
  }, {
    "id" : 138255,
    "reactomeId" : 10782529,
    "displayName" : "Phosphorylated OPTN translocates to the nucleus",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 438,
      "y" : 1847
    },
    "minX" : 214,
    "maxX" : 829,
    "minY" : 1841,
    "maxY" : 1853,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 214,
        "y" : 1843
      },
      "to" : {
        "x" : 438,
        "y" : 1847
      }
    }, {
      "from" : {
        "x" : 438,
        "y" : 1847
      },
      "to" : {
        "x" : 829,
        "y" : 1849
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 822,
        "y" : 1853
      },
      "b" : {
        "x" : 829,
        "y" : 1849
      },
      "c" : {
        "x" : 822,
        "y" : 1845
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 822,
        "y" : 1845
      }
    },
    "reactionShape" : {
      "a" : {
        "x" : 432,
        "y" : 1841
      },
      "b" : {
        "x" : 444,
        "y" : 1853
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 438,
        "y" : 1847
      }
    },
    "inputs" : [ {
      "id" : 138251
    } ],
    "outputs" : [ {
      "id" : 138256
    } ]
  }, {
    "id" : 138253,
    "reactomeId" : 10783648,
    "displayName" : "BORA binds PLK1 and AURKA",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 761,
      "y" : 2167
    },
    "minX" : 755,
    "maxX" : 772,
    "minY" : 2134,
    "maxY" : 2193,
    "reactionType" : "binding",
    "segments" : [ {
      "from" : {
        "x" : 772,
        "y" : 2193
      },
      "to" : {
        "x" : 761,
        "y" : 2167
      }
    }, {
      "from" : {
        "x" : 761,
        "y" : 2167
      },
      "to" : {
        "x" : 755,
        "y" : 2134
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 760,
        "y" : 2140
      },
      "b" : {
        "x" : 755,
        "y" : 2134
      },
      "c" : {
        "x" : 752,
        "y" : 2142
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 752,
        "y" : 2142
      }
    },
    "reactionShape" : {
      "c" : {
        "x" : 761,
        "y" : 2167
      },
      "r" : 5,
      "type" : "CIRCLE",
      "centre" : {
        "x" : 761,
        "y" : 2167
      }
    },
    "inputs" : [ {
      "id" : 138235,
      "points" : [ {
        "x" : 685,
        "y" : 2240
      } ]
    }, {
      "id" : 138254,
      "points" : [ {
        "x" : 846,
        "y" : 2191
      } ]
    }, {
      "id" : 138208,
      "points" : [ {
        "x" : 870,
        "y" : 2327
      } ]
    } ],
    "outputs" : [ {
      "id" : 138240
    } ]
  }, {
    "id" : 138259,
    "reactomeId" : 10783753,
    "displayName" : "Myosin phosphatase dephosphorylates PLK1",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 886,
      "y" : 1786
    },
    "minX" : 843,
    "maxX" : 925,
    "minY" : 1780,
    "maxY" : 1792,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 843,
        "y" : 1787
      },
      "to" : {
        "x" : 886,
        "y" : 1786
      }
    }, {
      "from" : {
        "x" : 886,
        "y" : 1786
      },
      "to" : {
        "x" : 925,
        "y" : 1786
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 880,
        "y" : 1780
      },
      "b" : {
        "x" : 892,
        "y" : 1792
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 886,
        "y" : 1786
      }
    },
    "inputs" : [ {
      "id" : 138258,
      "points" : [ {
        "x" : 777,
        "y" : 1741
      } ]
    }, {
      "id" : 138260,
      "points" : [ {
        "x" : 805,
        "y" : 1804
      } ]
    } ],
    "outputs" : [ {
      "id" : 138261,
      "points" : [ {
        "x" : 933,
        "y" : 1778
      } ]
    }, {
      "id" : 138262,
      "points" : [ {
        "x" : 930,
        "y" : 1805
      } ]
    } ],
    "catalysts" : [ {
      "id" : 138263,
      "points" : [ {
        "x" : 888,
        "y" : 1746
      } ]
    } ],
    "activators" : [ {
      "id" : 138256,
      "points" : [ {
        "x" : 884,
        "y" : 1836
      } ]
    } ]
  }, {
    "id" : 138257,
    "reactomeId" : 10783733,
    "displayName" : "Cytosolic PLK1 translocates to the nucleus",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 587,
      "y" : 2105
    },
    "minX" : 461,
    "maxX" : 756,
    "minY" : 1741,
    "maxY" : 2159,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 461,
        "y" : 2159
      },
      "to" : {
        "x" : 587,
        "y" : 2105
      }
    }, {
      "from" : {
        "x" : 587,
        "y" : 2105
      },
      "to" : {
        "x" : 756,
        "y" : 1741
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 757,
        "y" : 1749
      },
      "b" : {
        "x" : 756,
        "y" : 1741
      },
      "c" : {
        "x" : 749,
        "y" : 1746
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 749,
        "y" : 1746
      }
    },
    "reactionShape" : {
      "a" : {
        "x" : 581,
        "y" : 2099
      },
      "b" : {
        "x" : 593,
        "y" : 2111
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 587,
        "y" : 2105
      }
    },
    "inputs" : [ {
      "id" : 138225
    } ],
    "outputs" : [ {
      "id" : 138258
    } ]
  }, {
    "id" : 138264,
    "reactomeId" : 10786672,
    "displayName" : "CCNB:CDK1 phosphorylates BORA",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 894,
      "y" : 2103
    },
    "minX" : 888,
    "maxX" : 900,
    "minY" : 2069,
    "maxY" : 2123,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 894,
        "y" : 2069
      },
      "to" : {
        "x" : 894,
        "y" : 2103
      }
    }, {
      "from" : {
        "x" : 894,
        "y" : 2103
      },
      "to" : {
        "x" : 890,
        "y" : 2123
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 888,
        "y" : 2097
      },
      "b" : {
        "x" : 900,
        "y" : 2109
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 894,
        "y" : 2103
      }
    },
    "inputs" : [ {
      "id" : 138265,
      "points" : [ {
        "x" : 883,
        "y" : 2034
      } ]
    }, {
      "id" : 138266,
      "points" : [ {
        "x" : 852,
        "y" : 2066
      } ],
      "stoichiometry" : 9
    } ],
    "outputs" : [ {
      "id" : 138267,
      "points" : [ {
        "x" : 855,
        "y" : 2134
      } ],
      "stoichiometry" : 9
    }, {
      "id" : 138254,
      "points" : [ {
        "x" : 899,
        "y" : 2166
      } ]
    } ],
    "catalysts" : [ {
      "id" : 138268,
      "points" : [ {
        "x" : 1421,
        "y" : 2283
      }, {
        "x" : 1044,
        "y" : 2295
      }, {
        "x" : 987,
        "y" : 2159
      } ]
    } ]
  }, {
    "id" : 138269,
    "reactomeId" : 10786686,
    "displayName" : "CCNA:CDK1/2 complexes and CCNB1:CDK1 complexes phosphorylate FOXM1",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 749,
      "y" : 1435
    },
    "minX" : 743,
    "maxX" : 755,
    "minY" : 1407,
    "maxY" : 1460,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 750,
        "y" : 1407
      },
      "to" : {
        "x" : 749,
        "y" : 1435
      }
    }, {
      "from" : {
        "x" : 749,
        "y" : 1435
      },
      "to" : {
        "x" : 749,
        "y" : 1460
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 743,
        "y" : 1429
      },
      "b" : {
        "x" : 755,
        "y" : 1441
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 749,
        "y" : 1435
      }
    },
    "inputs" : [ {
      "id" : 138270,
      "points" : [ {
        "x" : 772,
        "y" : 1359
      } ]
    }, {
      "id" : 138271,
      "points" : [ {
        "x" : 727,
        "y" : 1360
      } ]
    } ],
    "outputs" : [ {
      "id" : 138272,
      "points" : [ {
        "x" : 821,
        "y" : 1504
      } ]
    }, {
      "id" : 138273,
      "points" : [ {
        "x" : 740,
        "y" : 1513
      } ]
    } ],
    "catalysts" : [ {
      "id" : 138274,
      "points" : [ {
        "x" : 791,
        "y" : 1435
      } ]
    } ]
  }, {
    "id" : 138275,
    "reactomeId" : 10786690,
    "displayName" : "PLK1 binds FOXM1",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 752,
      "y" : 1639
    },
    "minX" : 731,
    "maxX" : 795,
    "minY" : 1611,
    "maxY" : 1654,
    "reactionType" : "binding",
    "segments" : [ {
      "from" : {
        "x" : 731,
        "y" : 1654
      },
      "to" : {
        "x" : 752,
        "y" : 1639
      }
    }, {
      "from" : {
        "x" : 752,
        "y" : 1639
      },
      "to" : {
        "x" : 795,
        "y" : 1611
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 791,
        "y" : 1618
      },
      "b" : {
        "x" : 795,
        "y" : 1611
      },
      "c" : {
        "x" : 787,
        "y" : 1611
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 787,
        "y" : 1611
      }
    },
    "reactionShape" : {
      "c" : {
        "x" : 752,
        "y" : 1639
      },
      "r" : 5,
      "type" : "CIRCLE",
      "centre" : {
        "x" : 752,
        "y" : 1639
      }
    },
    "inputs" : [ {
      "id" : 138273,
      "points" : [ {
        "x" : 738,
        "y" : 1541
      } ]
    }, {
      "id" : 138258,
      "points" : [ {
        "x" : 756,
        "y" : 1711
      } ]
    } ],
    "outputs" : [ {
      "id" : 138276
    } ]
  }, {
    "id" : 138277,
    "reactomeId" : 10786697,
    "displayName" : "PLK1 phosphorylates FOXM1",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 944,
      "y" : 1597
    },
    "minX" : 909,
    "maxX" : 980,
    "minY" : 1591,
    "maxY" : 1603,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 909,
        "y" : 1602
      },
      "to" : {
        "x" : 944,
        "y" : 1597
      }
    }, {
      "from" : {
        "x" : 944,
        "y" : 1597
      },
      "to" : {
        "x" : 980,
        "y" : 1596
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 938,
        "y" : 1591
      },
      "b" : {
        "x" : 950,
        "y" : 1603
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 944,
        "y" : 1597
      }
    },
    "inputs" : [ {
      "id" : 138278,
      "points" : [ {
        "x" : 848,
        "y" : 1636
      } ],
      "stoichiometry" : 2
    }, {
      "id" : 138276,
      "points" : [ {
        "x" : 880,
        "y" : 1597
      } ]
    } ],
    "outputs" : [ {
      "id" : 138279,
      "points" : [ {
        "x" : 1023,
        "y" : 1464
      } ]
    }, {
      "id" : 138280,
      "points" : [ {
        "x" : 999,
        "y" : 1631
      } ],
      "stoichiometry" : 2
    }, {
      "id" : 138258,
      "points" : [ {
        "x" : 782,
        "y" : 1711
      } ]
    } ],
    "catalysts" : [ {
      "id" : 138276,
      "points" : [ {
        "x" : 880,
        "y" : 1578
      }, {
        "x" : 941,
        "y" : 1565
      } ]
    } ]
  }, {
    "id" : 138281,
    "reactomeId" : 10805757,
    "displayName" : "GTSE1 binds PLK1",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 775,
      "y" : 1955
    },
    "minX" : 769,
    "maxX" : 805,
    "minY" : 1949,
    "maxY" : 1983,
    "reactionType" : "binding",
    "segments" : [ {
      "from" : {
        "x" : 776,
        "y" : 1983
      },
      "to" : {
        "x" : 775,
        "y" : 1955
      }
    }, {
      "from" : {
        "x" : 775,
        "y" : 1955
      },
      "to" : {
        "x" : 805,
        "y" : 1949
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 799,
        "y" : 1954
      },
      "b" : {
        "x" : 805,
        "y" : 1949
      },
      "c" : {
        "x" : 797,
        "y" : 1946
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 797,
        "y" : 1946
      }
    },
    "reactionShape" : {
      "c" : {
        "x" : 775,
        "y" : 1955
      },
      "r" : 5,
      "type" : "CIRCLE",
      "centre" : {
        "x" : 775,
        "y" : 1955
      }
    },
    "inputs" : [ {
      "id" : 138225,
      "points" : [ {
        "x" : 482,
        "y" : 2163
      }, {
        "x" : 618,
        "y" : 2127
      } ]
    }, {
      "id" : 138282,
      "points" : [ {
        "x" : 1053,
        "y" : 2021
      } ]
    } ],
    "outputs" : [ {
      "id" : 138283
    } ]
  }, {
    "id" : 138284,
    "reactomeId" : 10805755,
    "displayName" : "PLK1 phosphorylates GTSE1",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 1035,
      "y" : 1939
    },
    "minX" : 996,
    "maxX" : 1126,
    "minY" : 1933,
    "maxY" : 1945,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 996,
        "y" : 1940
      },
      "to" : {
        "x" : 1035,
        "y" : 1939
      }
    }, {
      "from" : {
        "x" : 1035,
        "y" : 1939
      },
      "to" : {
        "x" : 1126,
        "y" : 1939
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 1029,
        "y" : 1933
      },
      "b" : {
        "x" : 1041,
        "y" : 1945
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 1035,
        "y" : 1939
      }
    },
    "inputs" : [ {
      "id" : 138285,
      "points" : [ {
        "x" : 963,
        "y" : 1958
      } ]
    }, {
      "id" : 138283,
      "points" : [ {
        "x" : 961,
        "y" : 1939
      } ]
    } ],
    "outputs" : [ {
      "id" : 138286,
      "points" : [ {
        "x" : 1191,
        "y" : 1957
      } ]
    }, {
      "id" : 138287,
      "points" : [ {
        "x" : 1175,
        "y" : 1929
      } ]
    }, {
      "id" : 138225,
      "points" : [ {
        "x" : 471,
        "y" : 2159
      }, {
        "x" : 606,
        "y" : 2115
      }, {
        "x" : 739,
        "y" : 1909
      }, {
        "x" : 1105,
        "y" : 1907
      } ]
    } ],
    "catalysts" : [ {
      "id" : 138283,
      "points" : [ {
        "x" : 961,
        "y" : 1926
      }, {
        "x" : 1034,
        "y" : 1914
      } ]
    } ]
  }, {
    "id" : 138290,
    "reactomeId" : 10805769,
    "displayName" : "GTSE1 binds CDKN1A",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 1911,
      "y" : 2612
    },
    "minX" : 1839,
    "maxX" : 1962,
    "minY" : 2606,
    "maxY" : 2618,
    "reactionType" : "binding",
    "segments" : [ {
      "from" : {
        "x" : 1839,
        "y" : 2613
      },
      "to" : {
        "x" : 1911,
        "y" : 2612
      }
    }, {
      "from" : {
        "x" : 1911,
        "y" : 2612
      },
      "to" : {
        "x" : 1962,
        "y" : 2611
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 1955,
        "y" : 2615
      },
      "b" : {
        "x" : 1962,
        "y" : 2611
      },
      "c" : {
        "x" : 1955,
        "y" : 2607
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 1955,
        "y" : 2607
      }
    },
    "reactionShape" : {
      "c" : {
        "x" : 1911,
        "y" : 2612
      },
      "r" : 5,
      "type" : "CIRCLE",
      "centre" : {
        "x" : 1911,
        "y" : 2612
      }
    },
    "inputs" : [ {
      "id" : 138291,
      "points" : [ {
        "x" : 1802,
        "y" : 2580
      } ]
    }, {
      "id" : 138292,
      "points" : [ {
        "x" : 2041,
        "y" : 2397
      } ]
    }, {
      "id" : 138293,
      "points" : [ {
        "x" : 1798,
        "y" : 2648
      } ]
    }, {
      "id" : 138282,
      "points" : [ {
        "x" : 1078,
        "y" : 2039
      }, {
        "x" : 1058,
        "y" : 2229
      }, {
        "x" : 1279,
        "y" : 2624
      } ]
    } ],
    "outputs" : [ {
      "id" : 138294
    } ]
  }, {
    "id" : 138288,
    "reactomeId" : 10805761,
    "displayName" : "GTSE1 translocates to the nucleus",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 1519,
      "y" : 1858
    },
    "minX" : 1292,
    "maxX" : 1704,
    "minY" : 1409,
    "maxY" : 1907,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 1292,
        "y" : 1907
      },
      "to" : {
        "x" : 1519,
        "y" : 1858
      }
    }, {
      "from" : {
        "x" : 1519,
        "y" : 1858
      },
      "to" : {
        "x" : 1531,
        "y" : 1628
      }
    }, {
      "from" : {
        "x" : 1531,
        "y" : 1628
      },
      "to" : {
        "x" : 1704,
        "y" : 1409
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 1703,
        "y" : 1417
      },
      "b" : {
        "x" : 1704,
        "y" : 1409
      },
      "c" : {
        "x" : 1697,
        "y" : 1412
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 1697,
        "y" : 1412
      }
    },
    "reactionShape" : {
      "a" : {
        "x" : 1513,
        "y" : 1852
      },
      "b" : {
        "x" : 1525,
        "y" : 1864
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 1519,
        "y" : 1858
      }
    },
    "inputs" : [ {
      "id" : 138287
    } ],
    "outputs" : [ {
      "id" : 138289
    } ]
  }, {
    "id" : 138295,
    "reactomeId" : 10805844,
    "displayName" : "TPX2 binds AURKA at centrosomes",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 308,
      "y" : 2355
    },
    "minX" : 275,
    "maxX" : 341,
    "minY" : 2327,
    "maxY" : 2361,
    "reactionType" : "binding",
    "segments" : [ {
      "from" : {
        "x" : 275,
        "y" : 2327
      },
      "to" : {
        "x" : 308,
        "y" : 2355
      }
    }, {
      "from" : {
        "x" : 308,
        "y" : 2355
      },
      "to" : {
        "x" : 341,
        "y" : 2358
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 334,
        "y" : 2361
      },
      "b" : {
        "x" : 341,
        "y" : 2358
      },
      "c" : {
        "x" : 334,
        "y" : 2353
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 334,
        "y" : 2353
      }
    },
    "reactionShape" : {
      "c" : {
        "x" : 308,
        "y" : 2355
      },
      "r" : 5,
      "type" : "CIRCLE",
      "centre" : {
        "x" : 308,
        "y" : 2355
      }
    },
    "inputs" : [ {
      "id" : 138296,
      "points" : [ {
        "x" : 234,
        "y" : 2327
      } ]
    }, {
      "id" : 138230,
      "points" : [ {
        "x" : 248,
        "y" : 2299
      } ]
    }, {
      "id" : 138297,
      "points" : [ {
        "x" : 246,
        "y" : 2348
      } ]
    } ],
    "outputs" : [ {
      "id" : 138298
    } ]
  }, {
    "id" : 138299,
    "reactomeId" : 10805849,
    "displayName" : "TPX2 promotes AURKA autophosphorylation",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 486,
      "y" : 2360
    },
    "minX" : 455,
    "maxX" : 522,
    "minY" : 2354,
    "maxY" : 2366,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 455,
        "y" : 2359
      },
      "to" : {
        "x" : 486,
        "y" : 2360
      }
    }, {
      "from" : {
        "x" : 486,
        "y" : 2360
      },
      "to" : {
        "x" : 522,
        "y" : 2360
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 480,
        "y" : 2354
      },
      "b" : {
        "x" : 492,
        "y" : 2366
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 486,
        "y" : 2360
      }
    },
    "inputs" : [ {
      "id" : 138298,
      "points" : [ {
        "x" : 429,
        "y" : 2360
      } ]
    }, {
      "id" : 138234,
      "points" : [ {
        "x" : 455,
        "y" : 2337
      } ]
    } ],
    "outputs" : [ {
      "id" : 138300,
      "points" : [ {
        "x" : 589,
        "y" : 2357
      } ]
    }, {
      "id" : 138237,
      "points" : [ {
        "x" : 536,
        "y" : 2342
      } ]
    } ],
    "catalysts" : [ {
      "id" : 138298,
      "points" : [ {
        "x" : 429,
        "y" : 2373
      }, {
        "x" : 487,
        "y" : 2390
      } ]
    } ]
  }, {
    "id" : 138301,
    "reactomeId" : 10805857,
    "displayName" : "PHLDA1 binds AURKA",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 265,
      "y" : 2469
    },
    "minX" : 259,
    "maxX" : 271,
    "minY" : 2455,
    "maxY" : 2493,
    "reactionType" : "binding",
    "segments" : [ {
      "from" : {
        "x" : 267,
        "y" : 2455
      },
      "to" : {
        "x" : 265,
        "y" : 2469
      }
    }, {
      "from" : {
        "x" : 265,
        "y" : 2469
      },
      "to" : {
        "x" : 265,
        "y" : 2493
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 261,
        "y" : 2486
      },
      "b" : {
        "x" : 265,
        "y" : 2493
      },
      "c" : {
        "x" : 269,
        "y" : 2486
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 269,
        "y" : 2486
      }
    },
    "reactionShape" : {
      "c" : {
        "x" : 265,
        "y" : 2469
      },
      "r" : 5,
      "type" : "CIRCLE",
      "centre" : {
        "x" : 265,
        "y" : 2469
      }
    },
    "inputs" : [ {
      "id" : 138302,
      "points" : [ {
        "x" : 292,
        "y" : 2445
      } ]
    }, {
      "id" : 138303,
      "points" : [ {
        "x" : 254,
        "y" : 2447
      } ]
    } ],
    "outputs" : [ {
      "id" : 138304
    } ]
  }, {
    "id" : 138173,
    "reactomeId" : 10742738,
    "displayName" : "Translocation of CCNA:p-T14-CDK1 to the nucleus",
    "schemaClass" : "BlackBoxEvent",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 355,
      "y" : 999
    },
    "minX" : 301,
    "maxX" : 983,
    "minY" : 993,
    "maxY" : 1005,
    "reactionType" : "omitted",
    "segments" : [ {
      "from" : {
        "x" : 301,
        "y" : 999
      },
      "to" : {
        "x" : 355,
        "y" : 999
      }
    }, {
      "from" : {
        "x" : 355,
        "y" : 999
      },
      "to" : {
        "x" : 983,
        "y" : 995
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 976,
        "y" : 999
      },
      "b" : {
        "x" : 983,
        "y" : 995
      },
      "c" : {
        "x" : 976,
        "y" : 991
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 976,
        "y" : 991
      }
    },
    "reactionShape" : {
      "a" : {
        "x" : 349,
        "y" : 993
      },
      "b" : {
        "x" : 361,
        "y" : 1005
      },
      "s" : "\\\\",
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 355,
        "y" : 999
      }
    },
    "inputs" : [ {
      "id" : 138174
    } ],
    "outputs" : [ {
      "id" : 138175
    } ]
  }, {
    "id" : 138176,
    "reactomeId" : 10742726,
    "displayName" : "CAK phosphorylates CDK1 bound to CCNA",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 1109,
      "y" : 1089
    },
    "minX" : 1103,
    "maxX" : 1115,
    "minY" : 1059,
    "maxY" : 1128,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 1109,
        "y" : 1059
      },
      "to" : {
        "x" : 1109,
        "y" : 1089
      }
    }, {
      "from" : {
        "x" : 1109,
        "y" : 1089
      },
      "to" : {
        "x" : 1109,
        "y" : 1128
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 1103,
        "y" : 1083
      },
      "b" : {
        "x" : 1115,
        "y" : 1095
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 1109,
        "y" : 1089
      }
    },
    "inputs" : [ {
      "id" : 138177,
      "points" : [ {
        "x" : 1126,
        "y" : 1045
      } ]
    }, {
      "id" : 138175,
      "points" : [ {
        "x" : 1064,
        "y" : 1015
      } ]
    } ],
    "outputs" : [ {
      "id" : 138178,
      "points" : [ {
        "x" : 1099,
        "y" : 1151
      } ]
    }, {
      "id" : 138179,
      "points" : [ {
        "x" : 1132,
        "y" : 1136
      } ]
    } ],
    "catalysts" : [ {
      "id" : 138180,
      "points" : [ {
        "x" : 1068,
        "y" : 1089
      } ]
    } ]
  }, {
    "id" : 138305,
    "reactomeId" : 10805863,
    "displayName" : "AURKA phosphorylates PHLDA1",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 258,
      "y" : 2610
    },
    "minX" : 252,
    "maxX" : 265,
    "minY" : 2593,
    "maxY" : 2659,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 262,
        "y" : 2593
      },
      "to" : {
        "x" : 258,
        "y" : 2610
      }
    }, {
      "from" : {
        "x" : 258,
        "y" : 2610
      },
      "to" : {
        "x" : 261,
        "y" : 2644
      }
    }, {
      "from" : {
        "x" : 261,
        "y" : 2644
      },
      "to" : {
        "x" : 265,
        "y" : 2659
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 252,
        "y" : 2604
      },
      "b" : {
        "x" : 264,
        "y" : 2616
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 258,
        "y" : 2610
      }
    },
    "inputs" : [ {
      "id" : 138306,
      "points" : [ {
        "x" : 247,
        "y" : 2585
      } ]
    }, {
      "id" : 138304,
      "points" : [ {
        "x" : 265,
        "y" : 2538
      } ]
    } ],
    "outputs" : [ {
      "id" : 138302,
      "points" : [ {
        "x" : 314,
        "y" : 2445
      }, {
        "x" : 315,
        "y" : 2602
      } ]
    }, {
      "id" : 138307,
      "points" : [ {
        "x" : 238,
        "y" : 2674
      } ]
    }, {
      "id" : 138308,
      "points" : [ {
        "x" : 295,
        "y" : 2676
      } ]
    } ],
    "catalysts" : [ {
      "id" : 138304,
      "points" : [ {
        "x" : 270,
        "y" : 2538
      }, {
        "x" : 288,
        "y" : 2608
      } ]
    } ]
  }, {
    "id" : 138181,
    "reactomeId" : 10742755,
    "displayName" : "WEE1 phosphorylates CCNA:CDK1",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 1243,
      "y" : 1089
    },
    "minX" : 1237,
    "maxX" : 1249,
    "minY" : 1055,
    "maxY" : 1123,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 1243,
        "y" : 1123
      },
      "to" : {
        "x" : 1243,
        "y" : 1089
      }
    }, {
      "from" : {
        "x" : 1243,
        "y" : 1089
      },
      "to" : {
        "x" : 1243,
        "y" : 1055
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 1237,
        "y" : 1083
      },
      "b" : {
        "x" : 1249,
        "y" : 1095
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 1243,
        "y" : 1089
      }
    },
    "inputs" : [ {
      "id" : 138182,
      "points" : [ {
        "x" : 1265,
        "y" : 1135
      } ]
    }, {
      "id" : 138179,
      "points" : [ {
        "x" : 1222,
        "y" : 1126
      } ]
    } ],
    "outputs" : [ {
      "id" : 138183,
      "points" : [ {
        "x" : 1313,
        "y" : 1033
      } ]
    }, {
      "id" : 138184,
      "points" : [ {
        "x" : 1284,
        "y" : 1003
      } ]
    } ],
    "catalysts" : [ {
      "id" : 138185,
      "points" : [ {
        "x" : 1315,
        "y" : 1088
      } ]
    } ]
  }, {
    "id" : 138309,
    "reactomeId" : 10805869,
    "displayName" : "SCF:FBXL7 binds AURKA",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 145,
      "y" : 2394
    },
    "minX" : 139,
    "maxX" : 188,
    "minY" : 2378,
    "maxY" : 2429,
    "reactionType" : "binding",
    "segments" : [ {
      "from" : {
        "x" : 188,
        "y" : 2378
      },
      "to" : {
        "x" : 145,
        "y" : 2394
      }
    }, {
      "from" : {
        "x" : 145,
        "y" : 2394
      },
      "to" : {
        "x" : 146,
        "y" : 2429
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 142,
        "y" : 2422
      },
      "b" : {
        "x" : 146,
        "y" : 2429
      },
      "c" : {
        "x" : 150,
        "y" : 2422
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 150,
        "y" : 2422
      }
    },
    "reactionShape" : {
      "c" : {
        "x" : 145,
        "y" : 2394
      },
      "r" : 5,
      "type" : "CIRCLE",
      "centre" : {
        "x" : 145,
        "y" : 2394
      }
    },
    "inputs" : [ {
      "id" : 138302,
      "points" : [ {
        "x" : 287,
        "y" : 2420
      } ]
    }, {
      "id" : 138310,
      "points" : [ {
        "x" : 138,
        "y" : 2302
      } ]
    } ],
    "outputs" : [ {
      "id" : 138311
    } ]
  }, {
    "id" : 138186,
    "reactomeId" : 10742765,
    "displayName" : "CDC25A dephosphorylates CCNA:CDK1",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 1431,
      "y" : 978
    },
    "minX" : 1425,
    "maxX" : 1437,
    "minY" : 950,
    "maxY" : 1011,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 1430,
        "y" : 1011
      },
      "to" : {
        "x" : 1431,
        "y" : 978
      }
    }, {
      "from" : {
        "x" : 1431,
        "y" : 978
      },
      "to" : {
        "x" : 1430,
        "y" : 950
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 1425,
        "y" : 972
      },
      "b" : {
        "x" : 1437,
        "y" : 984
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 1431,
        "y" : 978
      }
    },
    "inputs" : [ {
      "id" : 138187,
      "points" : [ {
        "x" : 1439,
        "y" : 1043
      } ],
      "stoichiometry" : 2
    }, {
      "id" : 138184,
      "points" : [ {
        "x" : 1361,
        "y" : 992
      } ]
    } ],
    "outputs" : [ {
      "id" : 138188,
      "points" : [ {
        "x" : 1491,
        "y" : 918
      } ],
      "stoichiometry" : 2
    }, {
      "id" : 138189,
      "points" : [ {
        "x" : 1377,
        "y" : 922
      } ]
    } ],
    "catalysts" : [ {
      "id" : 138190,
      "points" : [ {
        "x" : 1479,
        "y" : 1540
      }, {
        "x" : 1514,
        "y" : 1541
      }, {
        "x" : 1502,
        "y" : 983
      } ]
    } ]
  }, {
    "id" : 138315,
    "reactomeId" : 10805977,
    "displayName" : "Proteasome degrades AURKA ubiquitinated by SCF-FBXL7",
    "schemaClass" : "BlackBoxEvent",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 135,
      "y" : 2744
    },
    "minX" : 53,
    "maxX" : 150,
    "minY" : 2562,
    "maxY" : 2750,
    "reactionType" : "omitted",
    "segments" : [ {
      "from" : {
        "x" : 150,
        "y" : 2647
      },
      "to" : {
        "x" : 135,
        "y" : 2744
      }
    }, {
      "from" : {
        "x" : 135,
        "y" : 2744
      },
      "to" : {
        "x" : 63,
        "y" : 2688
      }
    }, {
      "from" : {
        "x" : 63,
        "y" : 2688
      },
      "to" : {
        "x" : 53,
        "y" : 2562
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 129,
        "y" : 2738
      },
      "b" : {
        "x" : 141,
        "y" : 2750
      },
      "s" : "\\\\",
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 135,
        "y" : 2744
      }
    },
    "inputs" : [ {
      "id" : 138314
    } ],
    "outputs" : [ {
      "id" : 138310,
      "points" : [ {
        "x" : 113,
        "y" : 2302
      }, {
        "x" : 66,
        "y" : 2363
      } ]
    }, {
      "id" : 138313,
      "points" : [ {
        "x" : 87,
        "y" : 2549
      } ],
      "stoichiometry" : 3
    } ],
    "catalysts" : [ {
      "id" : 138316,
      "points" : [ {
        "x" : 351,
        "y" : 2740
      } ]
    } ]
  }, {
    "id" : 138312,
    "reactomeId" : 10805975,
    "displayName" : "SCF-FBXL7 ubiquitinates AURKA",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 158,
      "y" : 2534
    },
    "minX" : 152,
    "maxX" : 164,
    "minY" : 2504,
    "maxY" : 2601,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 155,
        "y" : 2504
      },
      "to" : {
        "x" : 158,
        "y" : 2534
      }
    }, {
      "from" : {
        "x" : 158,
        "y" : 2534
      },
      "to" : {
        "x" : 154,
        "y" : 2601
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 150,
        "y" : 2594
      },
      "b" : {
        "x" : 154,
        "y" : 2601
      },
      "c" : {
        "x" : 158,
        "y" : 2594
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 158,
        "y" : 2594
      }
    },
    "reactionShape" : {
      "a" : {
        "x" : 152,
        "y" : 2528
      },
      "b" : {
        "x" : 164,
        "y" : 2540
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 158,
        "y" : 2534
      }
    },
    "inputs" : [ {
      "id" : 138311,
      "points" : [ {
        "x" : 150,
        "y" : 2474
      } ]
    }, {
      "id" : 138313,
      "points" : [ {
        "x" : 128,
        "y" : 2523
      } ],
      "stoichiometry" : 3
    } ],
    "outputs" : [ {
      "id" : 138314
    } ],
    "catalysts" : [ {
      "id" : 138311,
      "points" : [ {
        "x" : 163,
        "y" : 2474
      }, {
        "x" : 185,
        "y" : 2498
      } ]
    } ]
  }, {
    "id" : 138191,
    "reactomeId" : 10742706,
    "displayName" : "Formation of Cyclin B:Cdc2 complexes",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 218,
      "y" : 1286
    },
    "minX" : 204,
    "maxX" : 227,
    "minY" : 1254,
    "maxY" : 1325,
    "reactionType" : "binding",
    "segments" : [ {
      "from" : {
        "x" : 227,
        "y" : 1254
      },
      "to" : {
        "x" : 218,
        "y" : 1286
      }
    }, {
      "from" : {
        "x" : 218,
        "y" : 1286
      },
      "to" : {
        "x" : 210,
        "y" : 1319
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 208,
        "y" : 1311
      },
      "b" : {
        "x" : 210,
        "y" : 1319
      },
      "c" : {
        "x" : 216,
        "y" : 1313
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 216,
        "y" : 1313
      }
    },
    "reactionShape" : {
      "c" : {
        "x" : 218,
        "y" : 1286
      },
      "r" : 5,
      "type" : "CIRCLE",
      "centre" : {
        "x" : 218,
        "y" : 1286
      }
    },
    "inputs" : [ {
      "id" : 138192,
      "points" : [ {
        "x" : 246,
        "y" : 1244
      } ]
    }, {
      "id" : 138193,
      "points" : [ {
        "x" : 206,
        "y" : 1242
      } ]
    } ],
    "outputs" : [ {
      "id" : 138194
    } ]
  }, {
    "id" : 138317,
    "reactomeId" : 10805982,
    "displayName" : "Proteasome-mediated degradation of PolyUb-FBXL7",
    "schemaClass" : "BlackBoxEvent",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 525,
      "y" : 2910
    },
    "minX" : 420,
    "maxX" : 531,
    "minY" : 2894,
    "maxY" : 2936,
    "reactionType" : "omitted",
    "segments" : [ {
      "from" : {
        "x" : 470,
        "y" : 2894
      },
      "to" : {
        "x" : 525,
        "y" : 2910
      }
    }, {
      "from" : {
        "x" : 525,
        "y" : 2910
      },
      "to" : {
        "x" : 420,
        "y" : 2936
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 426,
        "y" : 2930
      },
      "b" : {
        "x" : 420,
        "y" : 2936
      },
      "c" : {
        "x" : 428,
        "y" : 2938
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 428,
        "y" : 2938
      }
    },
    "reactionShape" : {
      "a" : {
        "x" : 519,
        "y" : 2904
      },
      "b" : {
        "x" : 531,
        "y" : 2916
      },
      "s" : "\\\\",
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 525,
        "y" : 2910
      }
    },
    "inputs" : [ {
      "id" : 138318
    } ],
    "outputs" : [ {
      "id" : 138319,
      "stoichiometry" : 3
    } ],
    "catalysts" : [ {
      "id" : 138316,
      "points" : [ {
        "x" : 470,
        "y" : 2740
      }, {
        "x" : 528,
        "y" : 2740
      } ]
    } ]
  }, {
    "id" : 138195,
    "reactomeId" : 10742769,
    "displayName" : "Translocation of Cdc25 to the nucleus",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 1659,
      "y" : 1787
    },
    "minX" : 1564,
    "maxX" : 1665,
    "minY" : 991,
    "maxY" : 2092,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 1663,
        "y" : 2092
      },
      "to" : {
        "x" : 1659,
        "y" : 1787
      }
    }, {
      "from" : {
        "x" : 1659,
        "y" : 1787
      },
      "to" : {
        "x" : 1564,
        "y" : 991
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 1569,
        "y" : 997
      },
      "b" : {
        "x" : 1564,
        "y" : 991
      },
      "c" : {
        "x" : 1561,
        "y" : 998
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 1561,
        "y" : 998
      }
    },
    "reactionShape" : {
      "a" : {
        "x" : 1653,
        "y" : 1781
      },
      "b" : {
        "x" : 1665,
        "y" : 1793
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 1659,
        "y" : 1787
      }
    },
    "inputs" : [ {
      "id" : 138196
    } ],
    "outputs" : [ {
      "id" : 138197
    } ]
  }, {
    "id" : 138323,
    "reactomeId" : 10823107,
    "displayName" : "Formation of CCNA1:CDK1 complex",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 159,
      "y" : 1163
    },
    "minX" : 128,
    "maxX" : 167,
    "minY" : 1157,
    "maxY" : 1185,
    "reactionType" : "binding",
    "segments" : [ {
      "from" : {
        "x" : 167,
        "y" : 1185
      },
      "to" : {
        "x" : 159,
        "y" : 1163
      }
    }, {
      "from" : {
        "x" : 159,
        "y" : 1163
      },
      "to" : {
        "x" : 128,
        "y" : 1164
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 135,
        "y" : 1160
      },
      "b" : {
        "x" : 128,
        "y" : 1164
      },
      "c" : {
        "x" : 135,
        "y" : 1168
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 135,
        "y" : 1168
      }
    },
    "reactionShape" : {
      "c" : {
        "x" : 159,
        "y" : 1163
      },
      "r" : 5,
      "type" : "CIRCLE",
      "centre" : {
        "x" : 159,
        "y" : 1163
      }
    },
    "inputs" : [ {
      "id" : 138193,
      "points" : [ {
        "x" : 186,
        "y" : 1215
      } ]
    }, {
      "id" : 138324,
      "points" : [ {
        "x" : 121,
        "y" : 1223
      } ]
    } ],
    "outputs" : [ {
      "id" : 138325
    } ]
  }, {
    "id" : 138320,
    "reactomeId" : 10823109,
    "displayName" : "Formation of CCNA2:CDK1 complex",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 209,
      "y" : 1169
    },
    "minX" : 203,
    "maxX" : 251,
    "minY" : 1143,
    "maxY" : 1189,
    "reactionType" : "binding",
    "segments" : [ {
      "from" : {
        "x" : 209,
        "y" : 1189
      },
      "to" : {
        "x" : 209,
        "y" : 1169
      }
    }, {
      "from" : {
        "x" : 209,
        "y" : 1169
      },
      "to" : {
        "x" : 251,
        "y" : 1143
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 247,
        "y" : 1150
      },
      "b" : {
        "x" : 251,
        "y" : 1143
      },
      "c" : {
        "x" : 243,
        "y" : 1143
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 243,
        "y" : 1143
      }
    },
    "reactionShape" : {
      "c" : {
        "x" : 209,
        "y" : 1169
      },
      "r" : 5,
      "type" : "CIRCLE",
      "centre" : {
        "x" : 209,
        "y" : 1169
      }
    },
    "inputs" : [ {
      "id" : 138193,
      "points" : [ {
        "x" : 197,
        "y" : 1215
      } ]
    }, {
      "id" : 138321,
      "points" : [ {
        "x" : 246,
        "y" : 1187
      } ]
    } ],
    "outputs" : [ {
      "id" : 138322
    } ]
  }, {
    "id" : 138326,
    "reactomeId" : 10823208,
    "displayName" : "CDK1 phosphorylates CCNA",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 1367,
      "y" : 801
    },
    "minX" : 1361,
    "maxX" : 1373,
    "minY" : 750,
    "maxY" : 837,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 1368,
        "y" : 837
      },
      "to" : {
        "x" : 1367,
        "y" : 801
      }
    }, {
      "from" : {
        "x" : 1367,
        "y" : 801
      },
      "to" : {
        "x" : 1369,
        "y" : 750
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 1361,
        "y" : 795
      },
      "b" : {
        "x" : 1373,
        "y" : 807
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 1367,
        "y" : 801
      }
    },
    "inputs" : [ {
      "id" : 138189,
      "points" : [ {
        "x" : 1361,
        "y" : 887
      } ]
    }, {
      "id" : 138327,
      "points" : [ {
        "x" : 1404,
        "y" : 833
      } ]
    } ],
    "outputs" : [ {
      "id" : 138328,
      "points" : [ {
        "x" : 1381,
        "y" : 689
      } ]
    }, {
      "id" : 138329,
      "points" : [ {
        "x" : 1405,
        "y" : 755
      } ]
    } ],
    "catalysts" : [ {
      "id" : 138189,
      "points" : [ {
        "x" : 1351,
        "y" : 887
      }, {
        "x" : 1311,
        "y" : 835
      } ]
    } ]
  }, {
    "id" : 138198,
    "reactomeId" : 10740550,
    "displayName" : "Inactivation of Wee1 kinase",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 1722,
      "y" : 1260
    },
    "minX" : 1548,
    "maxX" : 1747,
    "minY" : 1180,
    "maxY" : 1266,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 1548,
        "y" : 1180
      },
      "to" : {
        "x" : 1722,
        "y" : 1260
      }
    }, {
      "from" : {
        "x" : 1722,
        "y" : 1260
      },
      "to" : {
        "x" : 1747,
        "y" : 1260
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 1716,
        "y" : 1254
      },
      "b" : {
        "x" : 1728,
        "y" : 1266
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 1722,
        "y" : 1260
      }
    },
    "inputs" : [ {
      "id" : 138185,
      "points" : [ {
        "x" : 1374,
        "y" : 1099
      } ]
    }, {
      "id" : 138199,
      "points" : [ {
        "x" : 1545,
        "y" : 1232
      } ]
    } ],
    "outputs" : [ {
      "id" : 138200,
      "points" : [ {
        "x" : 1757,
        "y" : 1299
      } ]
    }, {
      "id" : 138201,
      "points" : [ {
        "x" : 1773,
        "y" : 1260
      } ]
    } ],
    "catalysts" : [ {
      "id" : 138202,
      "points" : [ {
        "x" : 1721,
        "y" : 1223
      } ]
    } ]
  }, {
    "id" : 138330,
    "reactomeId" : 10823223,
    "displayName" : "CCNA:CDK1 complex translocates to the cytosol",
    "schemaClass" : "BlackBoxEvent",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 2068,
      "y" : 744
    },
    "minX" : 1473,
    "maxX" : 2294,
    "minY" : 678,
    "maxY" : 2486,
    "reactionType" : "omitted",
    "segments" : [ {
      "from" : {
        "x" : 1473,
        "y" : 678
      },
      "to" : {
        "x" : 2068,
        "y" : 744
      }
    }, {
      "from" : {
        "x" : 2068,
        "y" : 744
      },
      "to" : {
        "x" : 2294,
        "y" : 747
      }
    }, {
      "from" : {
        "x" : 2294,
        "y" : 747
      },
      "to" : {
        "x" : 2273,
        "y" : 2484
      }
    }, {
      "from" : {
        "x" : 2273,
        "y" : 2484
      },
      "to" : {
        "x" : 2195,
        "y" : 2486
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 2202,
        "y" : 2482
      },
      "b" : {
        "x" : 2195,
        "y" : 2486
      },
      "c" : {
        "x" : 2202,
        "y" : 2490
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 2202,
        "y" : 2490
      }
    },
    "reactionShape" : {
      "a" : {
        "x" : 2062,
        "y" : 738
      },
      "b" : {
        "x" : 2074,
        "y" : 750
      },
      "s" : "\\\\",
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 2068,
        "y" : 744
      }
    },
    "inputs" : [ {
      "id" : 138328
    } ],
    "outputs" : [ {
      "id" : 138331
    } ]
  }, {
    "id" : 138203,
    "reactomeId" : 10754861,
    "displayName" : "Recruitment of CDK11p58 to the centrosomes",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 632,
      "y" : 2435
    },
    "minX" : 597,
    "maxX" : 646,
    "minY" : 2429,
    "maxY" : 2453,
    "reactionType" : "binding",
    "segments" : [ {
      "from" : {
        "x" : 646,
        "y" : 2453
      },
      "to" : {
        "x" : 632,
        "y" : 2435
      }
    }, {
      "from" : {
        "x" : 632,
        "y" : 2435
      },
      "to" : {
        "x" : 597,
        "y" : 2435
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 604,
        "y" : 2431
      },
      "b" : {
        "x" : 597,
        "y" : 2435
      },
      "c" : {
        "x" : 604,
        "y" : 2439
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 604,
        "y" : 2439
      }
    },
    "reactionShape" : {
      "c" : {
        "x" : 632,
        "y" : 2435
      },
      "r" : 5,
      "type" : "CIRCLE",
      "centre" : {
        "x" : 632,
        "y" : 2435
      }
    },
    "inputs" : [ {
      "id" : 138204,
      "points" : [ {
        "x" : 664,
        "y" : 2444
      } ]
    }, {
      "id" : 138205,
      "points" : [ {
        "x" : 660,
        "y" : 2491
      } ]
    } ],
    "outputs" : [ {
      "id" : 138206
    } ]
  }, {
    "id" : 138207,
    "reactomeId" : 10754856,
    "displayName" : "Recruitment of Plk1 to centrosomes",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 799,
      "y" : 2414
    },
    "minX" : 776,
    "maxX" : 819,
    "minY" : 2385,
    "maxY" : 2435,
    "reactionType" : "binding",
    "segments" : [ {
      "from" : {
        "x" : 819,
        "y" : 2435
      },
      "to" : {
        "x" : 799,
        "y" : 2414
      }
    }, {
      "from" : {
        "x" : 799,
        "y" : 2414
      },
      "to" : {
        "x" : 776,
        "y" : 2385
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 783,
        "y" : 2388
      },
      "b" : {
        "x" : 776,
        "y" : 2385
      },
      "c" : {
        "x" : 777,
        "y" : 2393
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 777,
        "y" : 2393
      }
    },
    "reactionShape" : {
      "c" : {
        "x" : 799,
        "y" : 2414
      },
      "r" : 5,
      "type" : "CIRCLE",
      "centre" : {
        "x" : 799,
        "y" : 2414
      }
    },
    "inputs" : [ {
      "id" : 138205,
      "points" : [ {
        "x" : 688,
        "y" : 2491
      } ]
    }, {
      "id" : 138208,
      "points" : [ {
        "x" : 871,
        "y" : 2355
      } ]
    } ],
    "outputs" : [ {
      "id" : 138209
    } ],
    "activators" : [ {
      "id" : 138204,
      "points" : [ {
        "x" : 752,
        "y" : 2423
      } ]
    } ]
  }, {
    "id" : 138335,
    "reactomeId" : 10823263,
    "displayName" : "CCNA:CDK1 phosphorylates SGO1",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 1831,
      "y" : 657
    },
    "minX" : 1781,
    "maxX" : 1881,
    "minY" : 634,
    "maxY" : 663,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 1781,
        "y" : 634
      },
      "to" : {
        "x" : 1831,
        "y" : 657
      }
    }, {
      "from" : {
        "x" : 1831,
        "y" : 657
      },
      "to" : {
        "x" : 1881,
        "y" : 650
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 1825,
        "y" : 651
      },
      "b" : {
        "x" : 1837,
        "y" : 663
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 1831,
        "y" : 657
      }
    },
    "inputs" : [ {
      "id" : 138336,
      "points" : [ {
        "x" : 1737,
        "y" : 638
      } ]
    }, {
      "id" : 138337,
      "points" : [ {
        "x" : 1741,
        "y" : 609
      } ]
    } ],
    "outputs" : [ {
      "id" : 138338,
      "points" : [ {
        "x" : 1903,
        "y" : 665
      } ]
    }, {
      "id" : 138339,
      "points" : [ {
        "x" : 1944,
        "y" : 628
      } ]
    } ],
    "catalysts" : [ {
      "id" : 138328,
      "points" : [ {
        "x" : 1473,
        "y" : 674
      }, {
        "x" : 1805,
        "y" : 699
      } ]
    } ]
  }, {
    "id" : 138332,
    "reactomeId" : 10823230,
    "displayName" : "CCNA:CDK1 phosphorylates WEE1",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 1207,
      "y" : 830
    },
    "minX" : 1201,
    "maxX" : 1215,
    "minY" : 732,
    "maxY" : 1055,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 1215,
        "y" : 1055
      },
      "to" : {
        "x" : 1207,
        "y" : 830
      }
    }, {
      "from" : {
        "x" : 1207,
        "y" : 830
      },
      "to" : {
        "x" : 1209,
        "y" : 732
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 1201,
        "y" : 824
      },
      "b" : {
        "x" : 1213,
        "y" : 836
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 1207,
        "y" : 830
      }
    },
    "inputs" : [ {
      "id" : 138185,
      "points" : [ {
        "x" : 1315,
        "y" : 1081
      } ]
    }, {
      "id" : 138177,
      "points" : [ {
        "x" : 1163,
        "y" : 1034
      } ],
      "stoichiometry" : 2
    } ],
    "outputs" : [ {
      "id" : 138333,
      "points" : [ {
        "x" : 1141,
        "y" : 707
      } ]
    }, {
      "id" : 138334,
      "points" : [ {
        "x" : 1216,
        "y" : 667
      } ],
      "stoichiometry" : 2
    } ],
    "catalysts" : [ {
      "id" : 138328,
      "points" : [ {
        "x" : 1369,
        "y" : 689
      } ]
    } ]
  }, {
    "id" : 138210,
    "reactomeId" : 10754838,
    "displayName" : "Recruitment of additional gamma tubulin/ gamma TuRC to the centrosome",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 491,
      "y" : 2560
    },
    "minX" : 483,
    "maxX" : 497,
    "minY" : 2531,
    "maxY" : 2597,
    "reactionType" : "binding",
    "segments" : [ {
      "from" : {
        "x" : 494,
        "y" : 2531
      },
      "to" : {
        "x" : 491,
        "y" : 2560
      }
    }, {
      "from" : {
        "x" : 491,
        "y" : 2560
      },
      "to" : {
        "x" : 483,
        "y" : 2597
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 481,
        "y" : 2589
      },
      "b" : {
        "x" : 483,
        "y" : 2597
      },
      "c" : {
        "x" : 488,
        "y" : 2591
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 488,
        "y" : 2591
      }
    },
    "reactionShape" : {
      "c" : {
        "x" : 491,
        "y" : 2560
      },
      "r" : 5,
      "type" : "CIRCLE",
      "centre" : {
        "x" : 491,
        "y" : 2560
      }
    },
    "inputs" : [ {
      "id" : 138211,
      "points" : [ {
        "x" : 476,
        "y" : 2523
      } ]
    }, {
      "id" : 138205,
      "points" : [ {
        "x" : 619,
        "y" : 2511
      } ]
    } ],
    "outputs" : [ {
      "id" : 138212
    } ]
  }, {
    "id" : 138340,
    "reactomeId" : 10823221,
    "displayName" : "CCNA:CDK1 phosphorylates BORA",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 917,
      "y" : 2077
    },
    "minX" : 902,
    "maxX" : 923,
    "minY" : 2050,
    "maxY" : 2141,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 902,
        "y" : 2050
      },
      "to" : {
        "x" : 917,
        "y" : 2077
      }
    }, {
      "from" : {
        "x" : 917,
        "y" : 2077
      },
      "to" : {
        "x" : 914,
        "y" : 2141
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 911,
        "y" : 2071
      },
      "b" : {
        "x" : 923,
        "y" : 2083
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 917,
        "y" : 2077
      }
    },
    "inputs" : [ {
      "id" : 138265,
      "points" : [ {
        "x" : 888,
        "y" : 2034
      } ]
    }, {
      "id" : 138266,
      "points" : [ {
        "x" : 852,
        "y" : 2061
      } ],
      "stoichiometry" : 9
    } ],
    "outputs" : [ {
      "id" : 138254,
      "points" : [ {
        "x" : 908,
        "y" : 2166
      } ]
    }, {
      "id" : 138267,
      "points" : [ {
        "x" : 855,
        "y" : 2139
      } ],
      "stoichiometry" : 9
    } ],
    "catalysts" : [ {
      "id" : 138331,
      "points" : [ {
        "x" : 2021,
        "y" : 2493
      }, {
        "x" : 1245,
        "y" : 2537
      }, {
        "x" : 955,
        "y" : 2080
      } ]
    } ]
  }, {
    "id" : 138213,
    "reactomeId" : 10745018,
    "displayName" : "Phosphorylation of E2F1/E2F3 by Cyclin A:phosph-Cdk2(Thr 160)",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 767,
      "y" : 670
    },
    "minX" : 732,
    "maxX" : 800,
    "minY" : 664,
    "maxY" : 676,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 732,
        "y" : 668
      },
      "to" : {
        "x" : 767,
        "y" : 670
      }
    }, {
      "from" : {
        "x" : 767,
        "y" : 670
      },
      "to" : {
        "x" : 800,
        "y" : 668
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 761,
        "y" : 664
      },
      "b" : {
        "x" : 773,
        "y" : 676
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 767,
        "y" : 670
      }
    },
    "inputs" : [ {
      "id" : 138214,
      "points" : [ {
        "x" : 673,
        "y" : 694
      } ]
    }, {
      "id" : 138215,
      "points" : [ {
        "x" : 708,
        "y" : 662
      } ]
    } ],
    "outputs" : [ {
      "id" : 138216,
      "points" : [ {
        "x" : 824,
        "y" : 658
      } ]
    }, {
      "id" : 138217,
      "points" : [ {
        "x" : 829,
        "y" : 687
      } ]
    } ],
    "catalysts" : [ {
      "id" : 138215,
      "points" : [ {
        "x" : 708,
        "y" : 640
      }, {
        "x" : 765,
        "y" : 629
      } ]
    } ]
  }, {
    "id" : 138341,
    "reactomeId" : 10823235,
    "displayName" : "CCNA:CDK1 phosphorylates FZR1",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 1830,
      "y" : 764
    },
    "minX" : 1780,
    "maxX" : 1862,
    "minY" : 758,
    "maxY" : 770,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 1780,
        "y" : 761
      },
      "to" : {
        "x" : 1830,
        "y" : 764
      }
    }, {
      "from" : {
        "x" : 1830,
        "y" : 764
      },
      "to" : {
        "x" : 1862,
        "y" : 765
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 1824,
        "y" : 758
      },
      "b" : {
        "x" : 1836,
        "y" : 770
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 1830,
        "y" : 764
      }
    },
    "inputs" : [ {
      "id" : 138342,
      "points" : [ {
        "x" : 1746,
        "y" : 760
      } ]
    }, {
      "id" : 138343,
      "points" : [ {
        "x" : 1764,
        "y" : 798
      } ]
    } ],
    "outputs" : [ {
      "id" : 138344,
      "points" : [ {
        "x" : 1935,
        "y" : 768
      } ]
    }, {
      "id" : 138345,
      "points" : [ {
        "x" : 1901,
        "y" : 795
      } ]
    } ],
    "catalysts" : [ {
      "id" : 138328,
      "points" : [ {
        "x" : 1473,
        "y" : 679
      }, {
        "x" : 1821,
        "y" : 723
      } ]
    } ]
  }, {
    "id" : 138218,
    "reactomeId" : 10754842,
    "displayName" : "Loss of C-Nap-1 from centrosomes",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 662,
      "y" : 2550
    },
    "minX" : 656,
    "maxX" : 668,
    "minY" : 2519,
    "maxY" : 2582,
    "reactionType" : "dissociation",
    "segments" : [ {
      "from" : {
        "x" : 663,
        "y" : 2519
      },
      "to" : {
        "x" : 662,
        "y" : 2550
      }
    }, {
      "from" : {
        "x" : 662,
        "y" : 2550
      },
      "to" : {
        "x" : 660,
        "y" : 2582
      }
    } ],
    "reactionShape" : {
      "c" : {
        "x" : 662,
        "y" : 2550
      },
      "r" : 5,
      "r1" : 3,
      "type" : "DOUBLE_CIRCLE",
      "empty" : true,
      "centre" : {
        "x" : 662,
        "y" : 2550
      }
    },
    "inputs" : [ {
      "id" : 138205
    } ],
    "outputs" : [ {
      "id" : 138219,
      "points" : [ {
        "x" : 694,
        "y" : 2614
      } ]
    }, {
      "id" : 138220,
      "points" : [ {
        "x" : 633,
        "y" : 2606
      } ]
    } ]
  }, {
    "id" : 138346,
    "reactomeId" : 10823247,
    "displayName" : "CCNA:CDK1 phosphorylates TICRR",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 1892,
      "y" : 968
    },
    "minX" : 1853,
    "maxX" : 1930,
    "minY" : 962,
    "maxY" : 974,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 1853,
        "y" : 967
      },
      "to" : {
        "x" : 1892,
        "y" : 968
      }
    }, {
      "from" : {
        "x" : 1892,
        "y" : 968
      },
      "to" : {
        "x" : 1930,
        "y" : 970
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 1886,
        "y" : 962
      },
      "b" : {
        "x" : 1898,
        "y" : 974
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 1892,
        "y" : 968
      }
    },
    "inputs" : [ {
      "id" : 138347,
      "points" : [ {
        "x" : 1785,
        "y" : 967
      } ],
      "stoichiometry" : 4
    }, {
      "id" : 138348,
      "points" : [ {
        "x" : 1812,
        "y" : 1021
      } ]
    } ],
    "outputs" : [ {
      "id" : 138349,
      "points" : [ {
        "x" : 1986,
        "y" : 966
      } ],
      "stoichiometry" : 4
    }, {
      "id" : 138350,
      "points" : [ {
        "x" : 1969,
        "y" : 1011
      } ]
    } ],
    "catalysts" : [ {
      "id" : 138328,
      "points" : [ {
        "x" : 1413,
        "y" : 689
      }, {
        "x" : 1859,
        "y" : 883
      } ]
    } ]
  }, {
    "id" : 138351,
    "reactomeId" : 10823256,
    "displayName" : "CCNA:CDK1 phosphorylates OBI1",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 1384,
      "y" : 606
    },
    "minX" : 1348,
    "maxX" : 1428,
    "minY" : 598,
    "maxY" : 612,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 1348,
        "y" : 601
      },
      "to" : {
        "x" : 1384,
        "y" : 606
      }
    }, {
      "from" : {
        "x" : 1384,
        "y" : 606
      },
      "to" : {
        "x" : 1428,
        "y" : 598
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 1378,
        "y" : 600
      },
      "b" : {
        "x" : 1390,
        "y" : 612
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 1384,
        "y" : 606
      }
    },
    "inputs" : [ {
      "id" : 138352,
      "points" : [ {
        "x" : 1253,
        "y" : 596
      } ]
    }, {
      "id" : 138353,
      "points" : [ {
        "x" : 1309,
        "y" : 616
      } ]
    } ],
    "outputs" : [ {
      "id" : 138354,
      "points" : [ {
        "x" : 1524,
        "y" : 598
      } ]
    }, {
      "id" : 138355,
      "points" : [ {
        "x" : 1514,
        "y" : 633
      } ]
    } ],
    "catalysts" : [ {
      "id" : 138328,
      "points" : [ {
        "x" : 1384,
        "y" : 650
      } ]
    } ]
  }, {
    "id" : 138221,
    "reactomeId" : 10754787,
    "displayName" : "Plk1-mediated phosphorylation of Nlp",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 871,
      "y" : 2531
    },
    "minX" : 848,
    "maxX" : 895,
    "minY" : 2525,
    "maxY" : 2537,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 848,
        "y" : 2530
      },
      "to" : {
        "x" : 871,
        "y" : 2531
      }
    }, {
      "from" : {
        "x" : 871,
        "y" : 2531
      },
      "to" : {
        "x" : 895,
        "y" : 2531
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 865,
        "y" : 2525
      },
      "b" : {
        "x" : 877,
        "y" : 2537
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 871,
        "y" : 2531
      }
    },
    "inputs" : [ {
      "id" : 138222,
      "points" : [ {
        "x" : 837,
        "y" : 2545
      } ]
    }, {
      "id" : 138205,
      "points" : [ {
        "x" : 709,
        "y" : 2510
      } ]
    } ],
    "outputs" : [ {
      "id" : 138223,
      "points" : [ {
        "x" : 928,
        "y" : 2502
      } ]
    }, {
      "id" : 138224,
      "points" : [ {
        "x" : 907,
        "y" : 2547
      } ]
    } ],
    "catalysts" : [ {
      "id" : 138225,
      "points" : [ {
        "x" : 482,
        "y" : 2183
      }, {
        "x" : 707,
        "y" : 2210
      }, {
        "x" : 805,
        "y" : 2276
      } ]
    } ]
  }, {
    "id" : 138226,
    "reactomeId" : 10744997,
    "displayName" : "Association of Cyclin A:phospho-Cdk2(Thr 160) with E2F1/E2F3",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 539,
      "y" : 653
    },
    "minX" : 504,
    "maxX" : 582,
    "minY" : 647,
    "maxY" : 659,
    "reactionType" : "binding",
    "segments" : [ {
      "from" : {
        "x" : 504,
        "y" : 654
      },
      "to" : {
        "x" : 539,
        "y" : 653
      }
    }, {
      "from" : {
        "x" : 539,
        "y" : 653
      },
      "to" : {
        "x" : 582,
        "y" : 652
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 575,
        "y" : 656
      },
      "b" : {
        "x" : 582,
        "y" : 652
      },
      "c" : {
        "x" : 575,
        "y" : 648
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 575,
        "y" : 648
      }
    },
    "reactionShape" : {
      "c" : {
        "x" : 539,
        "y" : 653
      },
      "r" : 5,
      "type" : "CIRCLE",
      "centre" : {
        "x" : 539,
        "y" : 653
      }
    },
    "inputs" : [ {
      "id" : 138227,
      "points" : [ {
        "x" : 459,
        "y" : 627
      } ]
    }, {
      "id" : 138228,
      "points" : [ {
        "x" : 463,
        "y" : 694
      } ]
    } ],
    "outputs" : [ {
      "id" : 138215
    } ]
  }, {
    "id" : 138356,
    "reactomeId" : 10823269,
    "displayName" : "CCNA:CDK1 phosphorylates HJURP",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 1649,
      "y" : 463
    },
    "minX" : 1587,
    "maxX" : 1675,
    "minY" : 457,
    "maxY" : 469,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 1587,
        "y" : 458
      },
      "to" : {
        "x" : 1649,
        "y" : 463
      }
    }, {
      "from" : {
        "x" : 1649,
        "y" : 463
      },
      "to" : {
        "x" : 1675,
        "y" : 463
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 1643,
        "y" : 457
      },
      "b" : {
        "x" : 1655,
        "y" : 469
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 1649,
        "y" : 463
      }
    },
    "inputs" : [ {
      "id" : 138357,
      "points" : [ {
        "x" : 1538,
        "y" : 458
      } ]
    }, {
      "id" : 138358,
      "points" : [ {
        "x" : 1563,
        "y" : 425
      } ],
      "stoichiometry" : 2
    } ],
    "outputs" : [ {
      "id" : 138359,
      "points" : [ {
        "x" : 1753,
        "y" : 463
      } ]
    }, {
      "id" : 138360,
      "points" : [ {
        "x" : 1694,
        "y" : 428
      } ],
      "stoichiometry" : 2
    } ],
    "catalysts" : [ {
      "id" : 138328,
      "points" : [ {
        "x" : 1388,
        "y" : 650
      }, {
        "x" : 1435,
        "y" : 530
      } ]
    } ]
  }, {
    "id" : 138229,
    "reactomeId" : 10782548,
    "displayName" : "AJUBA binds centrosome-associated AURKA",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 322,
      "y" : 2279
    },
    "minX" : 301,
    "maxX" : 350,
    "minY" : 2273,
    "maxY" : 2285,
    "reactionType" : "binding",
    "segments" : [ {
      "from" : {
        "x" : 301,
        "y" : 2278
      },
      "to" : {
        "x" : 322,
        "y" : 2279
      }
    }, {
      "from" : {
        "x" : 322,
        "y" : 2279
      },
      "to" : {
        "x" : 350,
        "y" : 2278
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 343,
        "y" : 2282
      },
      "b" : {
        "x" : 350,
        "y" : 2278
      },
      "c" : {
        "x" : 343,
        "y" : 2274
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 343,
        "y" : 2274
      }
    },
    "reactionShape" : {
      "c" : {
        "x" : 322,
        "y" : 2279
      },
      "r" : 5,
      "type" : "CIRCLE",
      "centre" : {
        "x" : 322,
        "y" : 2279
      }
    },
    "inputs" : [ {
      "id" : 138230,
      "points" : [ {
        "x" : 278,
        "y" : 2278
      } ]
    }, {
      "id" : 138231,
      "points" : [ {
        "x" : 254,
        "y" : 2246
      } ]
    } ],
    "outputs" : [ {
      "id" : 138232
    } ]
  }, {
    "id" : 138361,
    "reactomeId" : 10823274,
    "displayName" : "CCNA:CDK1 phosphorylates MIS18BP1",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 1645,
      "y" : 524
    },
    "minX" : 1595,
    "maxX" : 1706,
    "minY" : 512,
    "maxY" : 543,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 1595,
        "y" : 543
      },
      "to" : {
        "x" : 1645,
        "y" : 524
      }
    }, {
      "from" : {
        "x" : 1645,
        "y" : 524
      },
      "to" : {
        "x" : 1706,
        "y" : 512
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 1639,
        "y" : 518
      },
      "b" : {
        "x" : 1651,
        "y" : 530
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 1645,
        "y" : 524
      }
    },
    "inputs" : [ {
      "id" : 138362,
      "points" : [ {
        "x" : 1558,
        "y" : 550
      } ]
    }, {
      "id" : 138358,
      "points" : [ {
        "x" : 1558,
        "y" : 425
      } ]
    } ],
    "outputs" : [ {
      "id" : 138363,
      "points" : [ {
        "x" : 1756,
        "y" : 516
      } ]
    }, {
      "id" : 138360,
      "points" : [ {
        "x" : 1701,
        "y" : 428
      } ]
    } ],
    "catalysts" : [ {
      "id" : 138328,
      "points" : [ {
        "x" : 1390,
        "y" : 650
      }, {
        "x" : 1441,
        "y" : 546
      } ]
    } ]
  }, {
    "id" : 138233,
    "reactomeId" : 10782546,
    "displayName" : "AJUBA facilitates AURKA autophosphorylation",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 494,
      "y" : 2278
    },
    "minX" : 468,
    "maxX" : 526,
    "minY" : 2272,
    "maxY" : 2284,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 468,
        "y" : 2277
      },
      "to" : {
        "x" : 494,
        "y" : 2278
      }
    }, {
      "from" : {
        "x" : 494,
        "y" : 2278
      },
      "to" : {
        "x" : 526,
        "y" : 2277
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 488,
        "y" : 2272
      },
      "b" : {
        "x" : 500,
        "y" : 2284
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 494,
        "y" : 2278
      }
    },
    "inputs" : [ {
      "id" : 138234,
      "points" : [ {
        "x" : 458,
        "y" : 2306
      } ],
      "stoichiometry" : 2
    }, {
      "id" : 138232,
      "points" : [ {
        "x" : 438,
        "y" : 2277
      } ]
    } ],
    "outputs" : [ {
      "id" : 138235,
      "points" : [ {
        "x" : 599,
        "y" : 2270
      } ]
    }, {
      "id" : 138236,
      "points" : [ {
        "x" : 553,
        "y" : 2231
      } ]
    }, {
      "id" : 138237,
      "points" : [ {
        "x" : 539,
        "y" : 2312
      } ],
      "stoichiometry" : 2
    } ],
    "catalysts" : [ {
      "id" : 138232,
      "points" : [ {
        "x" : 438,
        "y" : 2258
      }, {
        "x" : 471,
        "y" : 2242
      } ]
    } ]
  }, {
    "id" : 138238,
    "reactomeId" : 10783646,
    "displayName" : "AURKA phosphorylates PLK1",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 675,
      "y" : 2140
    },
    "minX" : 654,
    "maxX" : 699,
    "minY" : 2119,
    "maxY" : 2146,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 699,
        "y" : 2141
      },
      "to" : {
        "x" : 675,
        "y" : 2140
      }
    }, {
      "from" : {
        "x" : 675,
        "y" : 2140
      },
      "to" : {
        "x" : 654,
        "y" : 2119
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 669,
        "y" : 2134
      },
      "b" : {
        "x" : 681,
        "y" : 2146
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 675,
        "y" : 2140
      }
    },
    "inputs" : [ {
      "id" : 138239,
      "points" : [ {
        "x" : 710,
        "y" : 2152
      } ]
    }, {
      "id" : 138240,
      "points" : [ {
        "x" : 709,
        "y" : 2134
      } ]
    } ],
    "outputs" : [ {
      "id" : 138241,
      "points" : [ {
        "x" : 571,
        "y" : 2007
      } ]
    }, {
      "id" : 138235,
      "points" : [ {
        "x" : 644,
        "y" : 2240
      } ]
    }, {
      "id" : 138242,
      "points" : [ {
        "x" : 623,
        "y" : 2152
      } ]
    } ],
    "catalysts" : [ {
      "id" : 138240,
      "points" : [ {
        "x" : 705,
        "y" : 2105
      }, {
        "x" : 679,
        "y" : 2113
      } ]
    } ]
  } ],
  "compartments" : [ {
    "id" : 138366,
    "reactomeId" : 70101,
    "displayName" : "cytosol",
    "schemaClass" : "Compartment",
    "renderableClass" : "Compartment",
    "position" : {
      "x" : 1194,
      "y" : 1536
    },
    "minX" : 0,
    "maxX" : 2389,
    "minY" : 0,
    "maxY" : 3073,
    "prop" : {
      "x" : 0,
      "y" : 0,
      "width" : 2389,
      "height" : 3073
    },
    "textPosition" : {
      "x" : 55,
      "y" : 3023
    },
    "insets" : {
      "x" : 10,
      "y" : 10,
      "width" : 2369,
      "height" : 3053
    },
    "bgColor" : {
      "r" : 250,
      "g" : 240,
      "b" : 240
    },
    "componentIds" : [ 138193, 138191, 138192, 138194, 138372, 138203, 138204, 138205, 138206, 138207, 138208, 138209, 138210, 138211, 138212, 138219, 138220, 138218, 138224, 138223, 138221, 138222, 138196, 138419, 138422, 138367, 138229, 138230, 138231, 138232, 138233, 138234, 138235, 138236, 138237, 138240, 138239, 138241, 138238, 138242, 138245, 138246, 138423, 138424, 138245, 138253, 138265, 138381, 138249, 138251, 138252, 138257, 138264, 138254, 138268, 138425, 138426, 138282, 138283, 138281, 138284, 138286, 138287, 138285, 138290, 138292, 138293, 138294, 138291, 138391, 138428, 138295, 138297, 138298, 138299, 138300, 138301, 138303, 138304, 138305, 138306, 138308, 138430, 138431, 138309, 138311, 138310, 138312, 138314, 138315, 138316, 138318, 138317, 138302, 138307, 138296, 138313, 138429, 138432, 138402, 138411, 138319, 138320, 138321, 138322, 138323, 138324, 138325, 138415, 138439, 138440, 138174, 138331, 138266, 138267, 138340, 138435, 138436, 138437, 138435, 138437, 138436, 138225, 138243, 138244 ]
  }, {
    "id" : 138367,
    "reactomeId" : 7660,
    "displayName" : "nucleoplasm",
    "schemaClass" : "Compartment",
    "renderableClass" : "Compartment",
    "position" : {
      "x" : 1205,
      "y" : 1006
    },
    "minX" : 331,
    "maxX" : 2079,
    "minY" : 120,
    "maxY" : 1893,
    "prop" : {
      "x" : 331,
      "y" : 120,
      "width" : 1748,
      "height" : 1773
    },
    "textPosition" : {
      "x" : 1874,
      "y" : 1781
    },
    "insets" : {
      "x" : 341,
      "y" : 130,
      "width" : 1728,
      "height" : 1753
    },
    "bgColor" : {
      "r" : 250,
      "g" : 240,
      "b" : 240
    },
    "componentIds" : [ 138173, 138176, 138177, 138178, 138180, 138181, 138182, 138183, 138185, 138186, 138197, 138187, 138188, 138198, 138201, 138213, 138214, 138215, 138216, 138217, 138226, 138227, 138228, 138195, 138421, 138420, 138256, 138258, 138263, 138259, 138260, 138261, 138262, 138269, 138271, 138273, 138270, 138272, 138275, 138276, 138277, 138278, 138279, 138280, 138190, 138427, 138289, 138202, 138255, 138288, 138433, 138434, 138274, 138438, 138199, 138200, 138175, 138179, 138184, 138189, 138441, 138326, 138327, 138328, 138329, 138330, 138332, 138333, 138334, 138337, 138338, 138339, 138336, 138335, 138341, 138342, 138343, 138344, 138345, 138346, 138347, 138348, 138349, 138350, 138351, 138352, 138353, 138354, 138355, 138356, 138357, 138358, 138359, 138360, 138361, 138362, 138363, 138418, 138442 ]
  }, {
    "id" : 138381,
    "reactomeId" : 20699,
    "displayName" : "Golgi membrane",
    "schemaClass" : "Compartment",
    "renderableClass" : "Compartment",
    "position" : {
      "x" : 176,
      "y" : 2168
    },
    "minX" : 39,
    "maxX" : 314,
    "minY" : 2140,
    "maxY" : 2197,
    "prop" : {
      "x" : 39,
      "y" : 2140,
      "width" : 275,
      "height" : 57
    },
    "textPosition" : {
      "x" : 48,
      "y" : 2161
    },
    "bgColor" : {
      "r" : 250,
      "g" : 240,
      "b" : 240
    },
    "componentIds" : [ 138247, 138248, 138250 ]
  } ],
  "notes" : [ ],
  "links" : [ {
    "id" : 138439,
    "renderableClass" : "EntitySetAndMemberLink",
    "position" : {
      "x" : 242,
      "y" : 1126
    },
    "minX" : 233,
    "maxX" : 251,
    "minY" : 1120,
    "maxY" : 1132,
    "segments" : [ {
      "from" : {
        "x" : 251,
        "y" : 1126
      },
      "to" : {
        "x" : 233,
        "y" : 1126
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 236,
        "y" : 1120
      },
      "b" : {
        "x" : 248,
        "y" : 1132
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 242,
        "y" : 1126
      }
    },
    "inputs" : [ {
      "id" : 138322
    } ],
    "outputs" : [ {
      "id" : 138415
    } ]
  }, {
    "id" : 138437,
    "renderableClass" : "EntitySetAndMemberLink",
    "position" : {
      "x" : 278,
      "y" : 1511
    },
    "minX" : 260,
    "maxX" : 297,
    "minY" : 1244,
    "maxY" : 1779,
    "segments" : [ {
      "from" : {
        "x" : 297,
        "y" : 1779
      },
      "to" : {
        "x" : 260,
        "y" : 1244
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 272,
        "y" : 1505
      },
      "b" : {
        "x" : 284,
        "y" : 1517
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 278,
        "y" : 1511
      }
    },
    "inputs" : [ {
      "id" : 138411
    } ],
    "outputs" : [ {
      "id" : 138192
    } ]
  }, {
    "id" : 138442,
    "renderableClass" : "Interaction",
    "position" : {
      "x" : 1430,
      "y" : 1421
    },
    "minX" : 1364,
    "maxX" : 1445,
    "minY" : 1409,
    "maxY" : 1526,
    "interactionType" : "Activate",
    "segments" : [ {
      "from" : {
        "x" : 1364,
        "y" : 1409
      },
      "to" : {
        "x" : 1430,
        "y" : 1421
      }
    }, {
      "from" : {
        "x" : 1430,
        "y" : 1421
      },
      "to" : {
        "x" : 1445,
        "y" : 1526
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 1440,
        "y" : 1520
      },
      "b" : {
        "x" : 1445,
        "y" : 1526
      },
      "c" : {
        "x" : 1448,
        "y" : 1519
      },
      "type" : "ARROW",
      "empty" : true,
      "centre" : {
        "x" : 1448,
        "y" : 1519
      }
    },
    "reactionShape" : {
      "a" : {
        "x" : 1424,
        "y" : 1415
      },
      "b" : {
        "x" : 1436,
        "y" : 1427
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 1430,
        "y" : 1421
      }
    },
    "inputs" : [ {
      "id" : 138418
    } ],
    "outputs" : [ {
      "id" : 138190
    } ]
  }, {
    "id" : 138427,
    "renderableClass" : "EntitySetAndMemberLink",
    "position" : {
      "x" : 1504,
      "y" : 1258
    },
    "minX" : 1449,
    "maxX" : 1560,
    "minY" : 991,
    "maxY" : 1526,
    "segments" : [ {
      "from" : {
        "x" : 1449,
        "y" : 1526
      },
      "to" : {
        "x" : 1560,
        "y" : 991
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 1498,
        "y" : 1252
      },
      "b" : {
        "x" : 1510,
        "y" : 1264
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 1504,
        "y" : 1258
      }
    },
    "inputs" : [ {
      "id" : 138190
    } ],
    "outputs" : [ {
      "id" : 138197
    } ]
  }, {
    "id" : 138440,
    "renderableClass" : "EntitySetAndMemberLink",
    "position" : {
      "x" : 145,
      "y" : 1149
    },
    "minX" : 128,
    "maxX" : 162,
    "minY" : 1143,
    "maxY" : 1155,
    "segments" : [ {
      "from" : {
        "x" : 128,
        "y" : 1155
      },
      "to" : {
        "x" : 162,
        "y" : 1143
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 139,
        "y" : 1143
      },
      "b" : {
        "x" : 151,
        "y" : 1155
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 145,
        "y" : 1149
      }
    },
    "inputs" : [ {
      "id" : 138325
    } ],
    "outputs" : [ {
      "id" : 138415
    } ]
  }, {
    "id" : 138425,
    "renderableClass" : "EntitySetAndMemberLink",
    "position" : {
      "x" : 1484,
      "y" : 2313
    },
    "minX" : 1478,
    "maxX" : 1490,
    "minY" : 2305,
    "maxY" : 2321,
    "segments" : [ {
      "from" : {
        "x" : 1487,
        "y" : 2321
      },
      "to" : {
        "x" : 1481,
        "y" : 2305
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 1478,
        "y" : 2307
      },
      "b" : {
        "x" : 1490,
        "y" : 2319
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 1484,
        "y" : 2313
      }
    },
    "inputs" : [ {
      "id" : 138372
    } ],
    "outputs" : [ {
      "id" : 138268
    } ]
  }, {
    "id" : 138441,
    "renderableClass" : "EntitySetAndEntitySetLink",
    "position" : {
      "x" : 1116,
      "y" : 1167
    },
    "minX" : 884,
    "maxX" : 1349,
    "minY" : 922,
    "maxY" : 1413,
    "segments" : [ {
      "from" : {
        "x" : 1349,
        "y" : 922
      },
      "to" : {
        "x" : 884,
        "y" : 1413
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 1110,
        "y" : 1161
      },
      "b" : {
        "x" : 1122,
        "y" : 1173
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 1116,
        "y" : 1167
      }
    },
    "inputs" : [ {
      "id" : 138189
    } ],
    "outputs" : [ {
      "id" : 138274
    } ]
  }, {
    "id" : 138428,
    "renderableClass" : "Interaction",
    "position" : {
      "x" : 2074,
      "y" : 2292
    },
    "minX" : 2054,
    "maxX" : 2094,
    "minY" : 2216,
    "maxY" : 2369,
    "interactionType" : "Activate",
    "segments" : [ {
      "from" : {
        "x" : 2094,
        "y" : 2216
      },
      "to" : {
        "x" : 2054,
        "y" : 2369
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 2052,
        "y" : 2361
      },
      "b" : {
        "x" : 2054,
        "y" : 2369
      },
      "c" : {
        "x" : 2060,
        "y" : 2363
      },
      "type" : "ARROW",
      "empty" : true,
      "centre" : {
        "x" : 2060,
        "y" : 2363
      }
    },
    "reactionShape" : {
      "a" : {
        "x" : 2068,
        "y" : 2286
      },
      "b" : {
        "x" : 2080,
        "y" : 2298
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 2074,
        "y" : 2292
      }
    },
    "inputs" : [ {
      "id" : 138391
    } ],
    "outputs" : [ {
      "id" : 138292
    } ]
  } ],
  "shadows" : [ {
    "id" : 138443,
    "reactomeId" : 10825771,
    "displayName" : "G2/M Transition",
    "schemaClass" : "Pathway",
    "renderableClass" : "Shadow",
    "position" : {
      "x" : 1172,
      "y" : 1678
    },
    "minX" : 41,
    "maxX" : 2304,
    "minY" : 388,
    "maxY" : 2969,
    "prop" : {
      "x" : 41,
      "y" : 730,
      "width" : 2263,
      "height" : 2239
    },
    "points" : [ {
      "x" : 41,
      "y" : 388
    }, {
      "x" : 2304,
      "y" : 388
    }, {
      "x" : 2304,
      "y" : 2969
    }, {
      "x" : 41,
      "y" : 2969
    } ],
    "colour" : "#4684ee"
  }, {
    "id" : 138444,
    "reactomeId" : 10826145,
    "displayName" : "G2 Phase",
    "schemaClass" : "Pathway",
    "renderableClass" : "Shadow",
    "position" : {
      "x" : 657,
      "y" : 657
    },
    "minX" : 375,
    "maxX" : 939,
    "minY" : 584,
    "maxY" : 730,
    "prop" : {
      "x" : 375,
      "y" : 584,
      "width" : 564,
      "height" : 146
    },
    "points" : [ {
      "x" : 375,
      "y" : 584
    }, {
      "x" : 939,
      "y" : 584
    }, {
      "x" : 939,
      "y" : 730
    }, {
      "x" : 375,
      "y" : 730
    } ],
    "colour" : "#dc3912"
  } ],
  "minX" : 0,
  "maxX" : 2389,
  "minY" : 0,
  "maxY" : 3073,
  "disease" : false
}