{
  "dbId" : 10825323,
  "stableId" : "R-GGA-8956320",
  "displayName" : "Nucleotide biosynthesis",
  "nodes" : [ {
    "id" : 128805,
    "reactomeId" : 10738492,
    "displayName" : "PPAT tetramer",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 159,
      "y" : 48
    },
    "minX" : 100,
    "maxX" : 225,
    "minY" : 31,
    "maxY" : 59,
    "prop" : {
      "x" : 100,
      "y" : 37,
      "width" : 119,
      "height" : 22
    },
    "textPosition" : {
      "x" : 110,
      "y" : 38
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 219,
          "y" : 37
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 219,
          "y" : 37
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 128803,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 128809,
      "type" : "INPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 128804,
    "reactomeId" : 10735700,
    "displayName" : "PPAT dimer",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 156,
      "y" : 183
    },
    "minX" : 108,
    "maxX" : 210,
    "minY" : 128,
    "maxY" : 224,
    "prop" : {
      "x" : 108,
      "y" : 172,
      "width" : 96,
      "height" : 22
    },
    "textPosition" : {
      "x" : 117,
      "y" : 173
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 204,
          "y" : 172
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 204,
          "y" : 172
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 128803,
      "type" : "INPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 2,
        "shape" : {
          "a" : {
            "x" : 164,
            "y" : 128
          },
          "b" : {
            "x" : 176,
            "y" : 140
          },
          "type" : "BOX",
          "empty" : true,
          "centre" : {
            "x" : 170,
            "y" : 134
          }
        }
      }
    }, {
      "edgeId" : 128809,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 2,
        "shape" : {
          "a" : {
            "x" : 138,
            "y" : 129
          },
          "b" : {
            "x" : 150,
            "y" : 141
          },
          "type" : "BOX",
          "empty" : true,
          "centre" : {
            "x" : 144,
            "y" : 135
          }
        }
      }
    }, {
      "edgeId" : 128811,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 156,
          "y" : 197
        },
        "to" : {
          "x" : 156,
          "y" : 216
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 156,
          "y" : 220
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 156,
          "y" : 220
        }
      }
    } ]
  }, {
    "id" : 128807,
    "reactomeId" : 76577,
    "displayName" : "AMP",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 1948,
      "y" : 673
    },
    "minX" : 191,
    "maxX" : 2090,
    "minY" : 88,
    "maxY" : 688,
    "prop" : {
      "x" : 1924,
      "y" : 658,
      "width" : 48,
      "height" : 30
    },
    "textPosition" : {
      "x" : 1931,
      "y" : 662
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1967,
          "y" : 663
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1967,
          "y" : 663
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 128803,
      "type" : "ACTIVATOR",
      "segments" : [ {
        "from" : {
          "x" : 1975,
          "y" : 673
        },
        "to" : {
          "x" : 2090,
          "y" : 673
        }
      }, {
        "from" : {
          "x" : 2090,
          "y" : 673
        },
        "to" : {
          "x" : 2086,
          "y" : 330
        }
      }, {
        "from" : {
          "x" : 2086,
          "y" : 330
        },
        "to" : {
          "x" : 1890,
          "y" : 88
        }
      }, {
        "from" : {
          "x" : 1890,
          "y" : 88
        },
        "to" : {
          "x" : 191,
          "y" : 100
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 198,
          "y" : 96
        },
        "b" : {
          "x" : 191,
          "y" : 100
        },
        "c" : {
          "x" : 198,
          "y" : 104
        },
        "type" : "ARROW",
        "empty" : true,
        "centre" : {
          "x" : 198,
          "y" : 104
        }
      }
    }, {
      "edgeId" : 128915,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 1947,
          "y" : 655
        },
        "to" : {
          "x" : 1946,
          "y" : 616
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 1943,
          "y" : 648
        },
        "b" : {
          "x" : 1947,
          "y" : 655
        },
        "c" : {
          "x" : 1951,
          "y" : 648
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 1951,
          "y" : 648
        }
      }
    } ]
  }, {
    "id" : 128806,
    "reactomeId" : 29602,
    "displayName" : "IMP",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 1899,
      "y" : 238
    },
    "minX" : 191,
    "maxX" : 1939,
    "minY" : 96,
    "maxY" : 368,
    "prop" : {
      "x" : 1875,
      "y" : 223,
      "width" : 48,
      "height" : 30
    },
    "textPosition" : {
      "x" : 1884,
      "y" : 227
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1918,
          "y" : 228
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1918,
          "y" : 228
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 128803,
      "type" : "ACTIVATOR",
      "segments" : [ {
        "from" : {
          "x" : 1893,
          "y" : 220
        },
        "to" : {
          "x" : 1856,
          "y" : 110
        }
      }, {
        "from" : {
          "x" : 1856,
          "y" : 110
        },
        "to" : {
          "x" : 191,
          "y" : 100
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 198,
          "y" : 96
        },
        "b" : {
          "x" : 191,
          "y" : 100
        },
        "c" : {
          "x" : 198,
          "y" : 104
        },
        "type" : "ARROW",
        "empty" : true,
        "centre" : {
          "x" : 198,
          "y" : 104
        }
      }
    }, {
      "edgeId" : 128906,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1905,
          "y" : 256
        },
        "to" : {
          "x" : 1939,
          "y" : 337
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 128889,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 1872,
          "y" : 236
        },
        "to" : {
          "x" : 1836,
          "y" : 234
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 1865,
          "y" : 240
        },
        "b" : {
          "x" : 1872,
          "y" : 236
        },
        "c" : {
          "x" : 1865,
          "y" : 232
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 1865,
          "y" : 232
        }
      }
    }, {
      "edgeId" : 128891,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1877,
          "y" : 256
        },
        "to" : {
          "x" : 1711,
          "y" : 368
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 128808,
    "reactomeId" : 113578,
    "displayName" : "GMP",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 1712,
      "y" : 701
    },
    "minX" : 191,
    "maxX" : 2115,
    "minY" : 66,
    "maxY" : 716,
    "prop" : {
      "x" : 1688,
      "y" : 686,
      "width" : 48,
      "height" : 30
    },
    "textPosition" : {
      "x" : 1694,
      "y" : 690
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1731,
          "y" : 691
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1731,
          "y" : 691
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 128803,
      "type" : "ACTIVATOR",
      "segments" : [ {
        "from" : {
          "x" : 1739,
          "y" : 701
        },
        "to" : {
          "x" : 2115,
          "y" : 705
        }
      }, {
        "from" : {
          "x" : 2115,
          "y" : 705
        },
        "to" : {
          "x" : 2115,
          "y" : 329
        }
      }, {
        "from" : {
          "x" : 2115,
          "y" : 329
        },
        "to" : {
          "x" : 1925,
          "y" : 66
        }
      }, {
        "from" : {
          "x" : 1925,
          "y" : 66
        },
        "to" : {
          "x" : 191,
          "y" : 100
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 198,
          "y" : 96
        },
        "b" : {
          "x" : 191,
          "y" : 100
        },
        "c" : {
          "x" : 198,
          "y" : 104
        },
        "type" : "ARROW",
        "empty" : true,
        "centre" : {
          "x" : 198,
          "y" : 104
        }
      }
    }, {
      "edgeId" : 128898,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 1711,
          "y" : 683
        },
        "to" : {
          "x" : 1711,
          "y" : 653
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 1707,
          "y" : 676
        },
        "b" : {
          "x" : 1711,
          "y" : 683
        },
        "c" : {
          "x" : 1715,
          "y" : 676
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 1715,
          "y" : 676
        }
      }
    }, {
      "edgeId" : 128906,
      "type" : "INHIBITOR",
      "segments" : [ {
        "from" : {
          "x" : 1739,
          "y" : 690
        },
        "to" : {
          "x" : 1810,
          "y" : 660
        }
      }, {
        "from" : {
          "x" : 1810,
          "y" : 660
        },
        "to" : {
          "x" : 1823,
          "y" : 449
        }
      }, {
        "from" : {
          "x" : 1823,
          "y" : 449
        },
        "to" : {
          "x" : 1934,
          "y" : 407
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 1933,
          "y" : 403
        },
        "b" : {
          "x" : 1935,
          "y" : 411
        },
        "c" : {
          "x" : 1934,
          "y" : 407
        },
        "type" : "STOP",
        "centre" : {
          "x" : 1934,
          "y" : 407
        }
      }
    } ]
  }, {
    "id" : 128810,
    "reactomeId" : 73566,
    "displayName" : "PRPP",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 59,
      "y" : 232
    },
    "minX" : 35,
    "maxX" : 126,
    "minY" : 97,
    "maxY" : 247,
    "prop" : {
      "x" : 35,
      "y" : 217,
      "width" : 48,
      "height" : 30
    },
    "textPosition" : {
      "x" : 39,
      "y" : 221
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 78,
          "y" : 222
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 78,
          "y" : 222
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 128809,
      "type" : "ACTIVATOR",
      "segments" : [ {
        "from" : {
          "x" : 59,
          "y" : 214
        },
        "to" : {
          "x" : 60,
          "y" : 100
        }
      }, {
        "from" : {
          "x" : 60,
          "y" : 100
        },
        "to" : {
          "x" : 126,
          "y" : 101
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 119,
          "y" : 105
        },
        "b" : {
          "x" : 126,
          "y" : 101
        },
        "c" : {
          "x" : 119,
          "y" : 97
        },
        "type" : "ARROW",
        "empty" : true,
        "centre" : {
          "x" : 119,
          "y" : 97
        }
      }
    }, {
      "edgeId" : 128811,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 86,
          "y" : 232
        },
        "to" : {
          "x" : 118,
          "y" : 232
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 128813,
    "reactomeId" : 29356,
    "displayName" : "H2O",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 91,
      "y" : 311
    },
    "minX" : 67,
    "maxX" : 118,
    "minY" : 232,
    "maxY" : 326,
    "prop" : {
      "x" : 67,
      "y" : 296,
      "width" : 48,
      "height" : 30
    },
    "textPosition" : {
      "x" : 74,
      "y" : 300
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 110,
          "y" : 301
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 110,
          "y" : 301
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 128811,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 96,
          "y" : 293
        },
        "to" : {
          "x" : 118,
          "y" : 232
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ],
    "trivial" : true
  }, {
    "id" : 128812,
    "reactomeId" : 29472,
    "displayName" : "L-Gln",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 55,
      "y" : 272
    },
    "minX" : 27,
    "maxX" : 118,
    "minY" : 232,
    "maxY" : 287,
    "prop" : {
      "x" : 27,
      "y" : 257,
      "width" : 56,
      "height" : 30
    },
    "textPosition" : {
      "x" : 36,
      "y" : 261
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 78,
          "y" : 262
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 78,
          "y" : 262
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 128811,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 78,
          "y" : 254
        },
        "to" : {
          "x" : 118,
          "y" : 232
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 128815,
    "reactomeId" : 111294,
    "displayName" : "PPi",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 253,
      "y" : 334
    },
    "minX" : 190,
    "maxX" : 271,
    "minY" : 232,
    "maxY" : 350,
    "prop" : {
      "x" : 236,
      "y" : 319,
      "width" : 34,
      "height" : 31
    },
    "textPosition" : {
      "x" : 239,
      "y" : 324
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 265,
          "y" : 324
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 265,
          "y" : 324
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 128811,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 243,
          "y" : 316
        },
        "to" : {
          "x" : 190,
          "y" : 232
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 236,
          "y" : 312
        },
        "b" : {
          "x" : 243,
          "y" : 316
        },
        "c" : {
          "x" : 243,
          "y" : 308
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 243,
          "y" : 308
        }
      }
    } ]
  }, {
    "id" : 128814,
    "reactomeId" : 111292,
    "displayName" : "PRA",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 243,
      "y" : 232
    },
    "minX" : 190,
    "maxX" : 302,
    "minY" : 216,
    "maxY" : 247,
    "prop" : {
      "x" : 223,
      "y" : 217,
      "width" : 40,
      "height" : 30
    },
    "textPosition" : {
      "x" : 227,
      "y" : 221
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 258,
          "y" : 222
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 258,
          "y" : 222
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 128811,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 220,
          "y" : 232
        },
        "to" : {
          "x" : 190,
          "y" : 232
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 213,
          "y" : 236
        },
        "b" : {
          "x" : 220,
          "y" : 232
        },
        "c" : {
          "x" : 213,
          "y" : 228
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 213,
          "y" : 228
        }
      }
    }, {
      "edgeId" : 128817,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 266,
          "y" : 232
        },
        "to" : {
          "x" : 302,
          "y" : 232
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 128816,
    "reactomeId" : 29404,
    "displayName" : "L-Glu",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 175,
      "y" : 310
    },
    "minX" : 147,
    "maxX" : 204,
    "minY" : 232,
    "maxY" : 325,
    "prop" : {
      "x" : 147,
      "y" : 295,
      "width" : 56,
      "height" : 30
    },
    "textPosition" : {
      "x" : 156,
      "y" : 299
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 198,
          "y" : 300
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 198,
          "y" : 300
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 128811,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 177,
          "y" : 292
        },
        "to" : {
          "x" : 190,
          "y" : 232
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 175,
          "y" : 284
        },
        "b" : {
          "x" : 177,
          "y" : 292
        },
        "c" : {
          "x" : 182,
          "y" : 286
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 182,
          "y" : 286
        }
      }
    } ]
  }, {
    "id" : 128819,
    "reactomeId" : 29424,
    "displayName" : "Gly",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 263,
      "y" : 277
    },
    "minX" : 243,
    "maxX" : 302,
    "minY" : 232,
    "maxY" : 292,
    "prop" : {
      "x" : 243,
      "y" : 262,
      "width" : 40,
      "height" : 30
    },
    "textPosition" : {
      "x" : 250,
      "y" : 266
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 278,
          "y" : 267
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 278,
          "y" : 267
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 128817,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 276,
          "y" : 259
        },
        "to" : {
          "x" : 302,
          "y" : 232
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 128818,
    "reactomeId" : 113592,
    "displayName" : "ATP",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 310,
      "y" : 292
    },
    "minX" : 290,
    "maxX" : 331,
    "minY" : 232,
    "maxY" : 307,
    "prop" : {
      "x" : 290,
      "y" : 277,
      "width" : 40,
      "height" : 30
    },
    "textPosition" : {
      "x" : 294,
      "y" : 281
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 325,
          "y" : 282
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 325,
          "y" : 282
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 128817,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 308,
          "y" : 274
        },
        "to" : {
          "x" : 302,
          "y" : 232
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 128821,
    "reactomeId" : 29372,
    "displayName" : "Pi",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 423,
      "y" : 269
    },
    "minX" : 386,
    "maxX" : 440,
    "minY" : 231,
    "maxY" : 284,
    "prop" : {
      "x" : 407,
      "y" : 254,
      "width" : 32,
      "height" : 30
    },
    "textPosition" : {
      "x" : 413,
      "y" : 258
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 434,
          "y" : 259
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 434,
          "y" : 259
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 128817,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 408,
          "y" : 251
        },
        "to" : {
          "x" : 386,
          "y" : 231
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 400,
          "y" : 249
        },
        "b" : {
          "x" : 408,
          "y" : 251
        },
        "c" : {
          "x" : 406,
          "y" : 243
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 406,
          "y" : 243
        }
      }
    } ]
  }, {
    "id" : 128820,
    "reactomeId" : 111338,
    "displayName" : "PRGA",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 448,
      "y" : 232
    },
    "minX" : 386,
    "maxX" : 514,
    "minY" : 216,
    "maxY" : 247,
    "prop" : {
      "x" : 424,
      "y" : 217,
      "width" : 48,
      "height" : 30
    },
    "textPosition" : {
      "x" : 427,
      "y" : 221
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 467,
          "y" : 222
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 467,
          "y" : 222
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 128817,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 421,
          "y" : 231
        },
        "to" : {
          "x" : 386,
          "y" : 231
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 414,
          "y" : 235
        },
        "b" : {
          "x" : 421,
          "y" : 231
        },
        "c" : {
          "x" : 414,
          "y" : 227
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 414,
          "y" : 227
        }
      }
    }, {
      "edgeId" : 128825,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 475,
          "y" : 231
        },
        "to" : {
          "x" : 514,
          "y" : 231
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 128823,
    "reactomeId" : 29370,
    "displayName" : "ADP",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 417,
      "y" : 318
    },
    "minX" : 386,
    "maxX" : 442,
    "minY" : 231,
    "maxY" : 333,
    "prop" : {
      "x" : 393,
      "y" : 303,
      "width" : 48,
      "height" : 30
    },
    "textPosition" : {
      "x" : 400,
      "y" : 307
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 436,
          "y" : 308
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 436,
          "y" : 308
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 128817,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 411,
          "y" : 300
        },
        "to" : {
          "x" : 386,
          "y" : 231
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 405,
          "y" : 295
        },
        "b" : {
          "x" : 411,
          "y" : 300
        },
        "c" : {
          "x" : 412,
          "y" : 292
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 412,
          "y" : 292
        }
      }
    } ]
  }, {
    "id" : 128822,
    "reactomeId" : 70106,
    "displayName" : "H+",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 369,
      "y" : 290
    },
    "minX" : 349,
    "maxX" : 390,
    "minY" : 231,
    "maxY" : 305,
    "prop" : {
      "x" : 349,
      "y" : 275,
      "width" : 40,
      "height" : 30
    },
    "textPosition" : {
      "x" : 355,
      "y" : 279
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 384,
          "y" : 280
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 384,
          "y" : 280
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 128817,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 373,
          "y" : 272
        },
        "to" : {
          "x" : 386,
          "y" : 231
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 371,
          "y" : 264
        },
        "b" : {
          "x" : 373,
          "y" : 272
        },
        "c" : {
          "x" : 379,
          "y" : 267
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 379,
          "y" : 267
        }
      }
    } ],
    "trivial" : true
  }, {
    "id" : 128824,
    "reactomeId" : 10735685,
    "displayName" : "GART",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 451,
      "y" : 145
    },
    "minX" : 332,
    "maxX" : 1002,
    "minY" : 128,
    "maxY" : 224,
    "prop" : {
      "x" : 429,
      "y" : 134,
      "width" : 45,
      "height" : 22
    },
    "textPosition" : {
      "x" : 431,
      "y" : 134
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 474,
          "y" : 134
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 474,
          "y" : 134
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 128817,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 426,
          "y" : 152
        },
        "to" : {
          "x" : 337,
          "y" : 183
        }
      }, {
        "from" : {
          "x" : 337,
          "y" : 183
        },
        "to" : {
          "x" : 336,
          "y" : 215
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 336,
          "y" : 219
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 336,
          "y" : 219
        }
      }
    }, {
      "edgeId" : 128825,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 477,
          "y" : 154
        },
        "to" : {
          "x" : 551,
          "y" : 185
        }
      }, {
        "from" : {
          "x" : 551,
          "y" : 185
        },
        "to" : {
          "x" : 551,
          "y" : 216
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 551,
          "y" : 220
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 551,
          "y" : 220
        }
      }
    }, {
      "edgeId" : 128830,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 477,
          "y" : 145
        },
        "to" : {
          "x" : 998,
          "y" : 165
        }
      }, {
        "from" : {
          "x" : 998,
          "y" : 165
        },
        "to" : {
          "x" : 998,
          "y" : 216
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 998,
          "y" : 220
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 998,
          "y" : 220
        }
      }
    } ]
  }, {
    "id" : 128827,
    "reactomeId" : 111355,
    "displayName" : "THF",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 602,
      "y" : 313
    },
    "minX" : 579,
    "maxX" : 623,
    "minY" : 233,
    "maxY" : 328,
    "prop" : {
      "x" : 582,
      "y" : 298,
      "width" : 40,
      "height" : 30
    },
    "textPosition" : {
      "x" : 586,
      "y" : 302
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 617,
          "y" : 303
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 617,
          "y" : 303
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 128825,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 597,
          "y" : 295
        },
        "to" : {
          "x" : 579,
          "y" : 233
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 591,
          "y" : 289
        },
        "b" : {
          "x" : 597,
          "y" : 295
        },
        "c" : {
          "x" : 599,
          "y" : 287
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 599,
          "y" : 287
        }
      }
    } ]
  }, {
    "id" : 128826,
    "reactomeId" : 419151,
    "displayName" : "10-formyl-THF",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 510,
      "y" : 287
    },
    "minX" : 447,
    "maxX" : 575,
    "minY" : 231,
    "maxY" : 302,
    "prop" : {
      "x" : 447,
      "y" : 272,
      "width" : 127,
      "height" : 30
    },
    "textPosition" : {
      "x" : 464,
      "y" : 276
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 569,
          "y" : 277
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 569,
          "y" : 277
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 128825,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 511,
          "y" : 269
        },
        "to" : {
          "x" : 514,
          "y" : 231
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 128829,
    "reactomeId" : 70106,
    "displayName" : "H+",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 629,
      "y" : 276
    },
    "minX" : 579,
    "maxX" : 650,
    "minY" : 233,
    "maxY" : 291,
    "prop" : {
      "x" : 609,
      "y" : 261,
      "width" : 40,
      "height" : 30
    },
    "textPosition" : {
      "x" : 615,
      "y" : 265
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 644,
          "y" : 266
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 644,
          "y" : 266
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 128825,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 611,
          "y" : 258
        },
        "to" : {
          "x" : 579,
          "y" : 233
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 603,
          "y" : 257
        },
        "b" : {
          "x" : 611,
          "y" : 258
        },
        "c" : {
          "x" : 608,
          "y" : 251
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 608,
          "y" : 251
        }
      }
    } ],
    "trivial" : true
  }, {
    "id" : 128828,
    "reactomeId" : 111354,
    "displayName" : "N-Formyl-GAR",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 666,
      "y" : 232
    },
    "minX" : 579,
    "maxX" : 727,
    "minY" : 216,
    "maxY" : 247,
    "prop" : {
      "x" : 607,
      "y" : 217,
      "width" : 119,
      "height" : 30
    },
    "textPosition" : {
      "x" : 621,
      "y" : 221
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 721,
          "y" : 222
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 721,
          "y" : 222
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 128825,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 604,
          "y" : 232
        },
        "to" : {
          "x" : 579,
          "y" : 233
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 597,
          "y" : 236
        },
        "b" : {
          "x" : 604,
          "y" : 232
        },
        "c" : {
          "x" : 597,
          "y" : 228
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 597,
          "y" : 228
        }
      }
    } ]
  }, {
    "id" : 128831,
    "reactomeId" : 113592,
    "displayName" : "ATP",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 933,
      "y" : 190
    },
    "minX" : 913,
    "maxX" : 957,
    "minY" : 174,
    "maxY" : 232,
    "prop" : {
      "x" : 913,
      "y" : 175,
      "width" : 40,
      "height" : 30
    },
    "textPosition" : {
      "x" : 917,
      "y" : 179
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 948,
          "y" : 180
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 948,
          "y" : 180
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 128830,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 941,
          "y" : 208
        },
        "to" : {
          "x" : 957,
          "y" : 232
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 128833,
    "reactomeId" : 29370,
    "displayName" : "ADP",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 1013,
      "y" : 283
    },
    "minX" : 993,
    "maxX" : 1035,
    "minY" : 233,
    "maxY" : 299,
    "prop" : {
      "x" : 993,
      "y" : 268,
      "width" : 41,
      "height" : 31
    },
    "textPosition" : {
      "x" : 997,
      "y" : 273
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1029,
          "y" : 273
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1029,
          "y" : 273
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 128830,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 1019,
          "y" : 265
        },
        "to" : {
          "x" : 1035,
          "y" : 233
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 1019,
          "y" : 257
        },
        "b" : {
          "x" : 1019,
          "y" : 265
        },
        "c" : {
          "x" : 1026,
          "y" : 261
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 1026,
          "y" : 261
        }
      }
    } ]
  }, {
    "id" : 128832,
    "reactomeId" : 111369,
    "displayName" : "FGAM",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 897,
      "y" : 232
    },
    "minX" : 869,
    "maxX" : 957,
    "minY" : 216,
    "maxY" : 247,
    "prop" : {
      "x" : 869,
      "y" : 217,
      "width" : 56,
      "height" : 30
    },
    "textPosition" : {
      "x" : 876,
      "y" : 221
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 920,
          "y" : 222
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 920,
          "y" : 222
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 128830,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 928,
          "y" : 232
        },
        "to" : {
          "x" : 957,
          "y" : 232
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 128835,
    "reactomeId" : 29372,
    "displayName" : "Pi",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 1065,
      "y" : 283
    },
    "minX" : 1035,
    "maxX" : 1082,
    "minY" : 233,
    "maxY" : 298,
    "prop" : {
      "x" : 1049,
      "y" : 268,
      "width" : 32,
      "height" : 30
    },
    "textPosition" : {
      "x" : 1055,
      "y" : 272
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1076,
          "y" : 273
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1076,
          "y" : 273
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 128830,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 1056,
          "y" : 265
        },
        "to" : {
          "x" : 1035,
          "y" : 233
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 1049,
          "y" : 261
        },
        "b" : {
          "x" : 1056,
          "y" : 265
        },
        "c" : {
          "x" : 1056,
          "y" : 257
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 1056,
          "y" : 257
        }
      }
    } ]
  }, {
    "id" : 128834,
    "reactomeId" : 111370,
    "displayName" : "AIR",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 1091,
      "y" : 232
    },
    "minX" : 1035,
    "maxX" : 1138,
    "minY" : 216,
    "maxY" : 247,
    "prop" : {
      "x" : 1071,
      "y" : 217,
      "width" : 40,
      "height" : 30
    },
    "textPosition" : {
      "x" : 1077,
      "y" : 221
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1106,
          "y" : 222
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1106,
          "y" : 222
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 128837,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1114,
          "y" : 232
        },
        "to" : {
          "x" : 1138,
          "y" : 233
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 128830,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 1068,
          "y" : 232
        },
        "to" : {
          "x" : 1035,
          "y" : 233
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 1061,
          "y" : 236
        },
        "b" : {
          "x" : 1068,
          "y" : 232
        },
        "c" : {
          "x" : 1061,
          "y" : 228
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 1061,
          "y" : 228
        }
      }
    } ]
  }, {
    "id" : 128836,
    "reactomeId" : 70106,
    "displayName" : "H+",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 1070,
      "y" : 190
    },
    "minX" : 1035,
    "maxX" : 1091,
    "minY" : 174,
    "maxY" : 233,
    "prop" : {
      "x" : 1050,
      "y" : 175,
      "width" : 40,
      "height" : 30
    },
    "textPosition" : {
      "x" : 1056,
      "y" : 179
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1085,
          "y" : 180
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1085,
          "y" : 180
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 128830,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 1057,
          "y" : 208
        },
        "to" : {
          "x" : 1035,
          "y" : 233
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 1055,
          "y" : 216
        },
        "b" : {
          "x" : 1057,
          "y" : 208
        },
        "c" : {
          "x" : 1049,
          "y" : 211
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 1049,
          "y" : 211
        }
      }
    } ],
    "trivial" : true
  }, {
    "id" : 128839,
    "reactomeId" : 111395,
    "displayName" : "CAIR",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 1243,
      "y" : 232
    },
    "minX" : 1188,
    "maxX" : 1295,
    "minY" : 216,
    "maxY" : 247,
    "prop" : {
      "x" : 1219,
      "y" : 217,
      "width" : 48,
      "height" : 30
    },
    "textPosition" : {
      "x" : 1225,
      "y" : 221
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1262,
          "y" : 222
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1262,
          "y" : 222
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 128837,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 1216,
          "y" : 232
        },
        "to" : {
          "x" : 1188,
          "y" : 234
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 1209,
          "y" : 236
        },
        "b" : {
          "x" : 1216,
          "y" : 232
        },
        "c" : {
          "x" : 1209,
          "y" : 229
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 1209,
          "y" : 229
        }
      }
    }, {
      "edgeId" : 128842,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1270,
          "y" : 232
        },
        "to" : {
          "x" : 1295,
          "y" : 232
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 128838,
    "reactomeId" : 113528,
    "displayName" : "CO2",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 1124,
      "y" : 283
    },
    "minX" : 1100,
    "maxX" : 1149,
    "minY" : 233,
    "maxY" : 298,
    "prop" : {
      "x" : 1100,
      "y" : 268,
      "width" : 48,
      "height" : 30
    },
    "textPosition" : {
      "x" : 1107,
      "y" : 272
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1143,
          "y" : 273
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1143,
          "y" : 273
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 128837,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1128,
          "y" : 265
        },
        "to" : {
          "x" : 1138,
          "y" : 233
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ],
    "trivial" : true
  }, {
    "id" : 128841,
    "reactomeId" : 10735675,
    "displayName" : "PAICS octamer",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 1249,
      "y" : 183
    },
    "minX" : 1160,
    "maxX" : 1334,
    "minY" : 166,
    "maxY" : 225,
    "prop" : {
      "x" : 1190,
      "y" : 172,
      "width" : 119,
      "height" : 22
    },
    "textPosition" : {
      "x" : 1200,
      "y" : 173
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1309,
          "y" : 172
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1309,
          "y" : 172
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 128837,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 1187,
          "y" : 184
        },
        "to" : {
          "x" : 1164,
          "y" : 185
        }
      }, {
        "from" : {
          "x" : 1164,
          "y" : 185
        },
        "to" : {
          "x" : 1164,
          "y" : 217
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 1164,
          "y" : 221
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1164,
          "y" : 221
        }
      }
    }, {
      "edgeId" : 128842,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 1312,
          "y" : 184
        },
        "to" : {
          "x" : 1330,
          "y" : 185
        }
      }, {
        "from" : {
          "x" : 1330,
          "y" : 185
        },
        "to" : {
          "x" : 1330,
          "y" : 216
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 1330,
          "y" : 220
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1330,
          "y" : 220
        }
      }
    } ]
  }, {
    "id" : 128840,
    "reactomeId" : 70106,
    "displayName" : "H+",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 1189,
      "y" : 283
    },
    "minX" : 1169,
    "maxX" : 1210,
    "minY" : 234,
    "maxY" : 298,
    "prop" : {
      "x" : 1169,
      "y" : 268,
      "width" : 40,
      "height" : 30
    },
    "textPosition" : {
      "x" : 1175,
      "y" : 272
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1204,
          "y" : 273
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1204,
          "y" : 273
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 128837,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 1188,
          "y" : 265
        },
        "to" : {
          "x" : 1188,
          "y" : 234
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 1184,
          "y" : 258
        },
        "b" : {
          "x" : 1188,
          "y" : 265
        },
        "c" : {
          "x" : 1192,
          "y" : 258
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 1192,
          "y" : 258
        }
      }
    } ],
    "trivial" : true
  }, {
    "id" : 128843,
    "reactomeId" : 113592,
    "displayName" : "ATP",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 1313,
      "y" : 283
    },
    "minX" : 1293,
    "maxX" : 1334,
    "minY" : 232,
    "maxY" : 298,
    "prop" : {
      "x" : 1293,
      "y" : 268,
      "width" : 40,
      "height" : 30
    },
    "textPosition" : {
      "x" : 1297,
      "y" : 272
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1328,
          "y" : 273
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1328,
          "y" : 273
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 128842,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1307,
          "y" : 265
        },
        "to" : {
          "x" : 1295,
          "y" : 232
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 128845,
    "reactomeId" : 111399,
    "displayName" : "SAICAR",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 1430,
      "y" : 232
    },
    "minX" : 1355,
    "maxX" : 1463,
    "minY" : 216,
    "maxY" : 247,
    "prop" : {
      "x" : 1398,
      "y" : 217,
      "width" : 64,
      "height" : 30
    },
    "textPosition" : {
      "x" : 1404,
      "y" : 221
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1457,
          "y" : 222
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1457,
          "y" : 222
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 128842,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 1395,
          "y" : 232
        },
        "to" : {
          "x" : 1355,
          "y" : 232
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 1388,
          "y" : 236
        },
        "b" : {
          "x" : 1395,
          "y" : 232
        },
        "c" : {
          "x" : 1388,
          "y" : 228
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 1388,
          "y" : 228
        }
      }
    }, {
      "edgeId" : 128849,
      "type" : "INPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 128844,
    "reactomeId" : 29448,
    "displayName" : "L-Asp",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 1249,
      "y" : 283
    },
    "minX" : 1221,
    "maxX" : 1295,
    "minY" : 232,
    "maxY" : 298,
    "prop" : {
      "x" : 1221,
      "y" : 268,
      "width" : 56,
      "height" : 30
    },
    "textPosition" : {
      "x" : 1228,
      "y" : 272
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1272,
          "y" : 273
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1272,
          "y" : 273
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 128842,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1262,
          "y" : 265
        },
        "to" : {
          "x" : 1295,
          "y" : 232
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 128847,
    "reactomeId" : 70106,
    "displayName" : "H+",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 1385,
      "y" : 186
    },
    "minX" : 1355,
    "maxX" : 1406,
    "minY" : 170,
    "maxY" : 232,
    "prop" : {
      "x" : 1365,
      "y" : 171,
      "width" : 40,
      "height" : 30
    },
    "textPosition" : {
      "x" : 1371,
      "y" : 175
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1400,
          "y" : 176
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1400,
          "y" : 176
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 128842,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 1375,
          "y" : 204
        },
        "to" : {
          "x" : 1355,
          "y" : 232
        }
      } ],
      "stoichiometry" : {
        "value" : 2,
        "shape" : {
          "a" : {
            "x" : 1359,
            "y" : 212
          },
          "b" : {
            "x" : 1371,
            "y" : 224
          },
          "type" : "BOX",
          "empty" : true,
          "centre" : {
            "x" : 1365,
            "y" : 218
          }
        }
      },
      "endShape" : {
        "a" : {
          "x" : 1374,
          "y" : 212
        },
        "b" : {
          "x" : 1375,
          "y" : 204
        },
        "c" : {
          "x" : 1368,
          "y" : 207
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 1368,
          "y" : 207
        }
      }
    } ],
    "trivial" : true
  }, {
    "id" : 128846,
    "reactomeId" : 29370,
    "displayName" : "ADP",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 1377,
      "y" : 284
    },
    "minX" : 1355,
    "maxX" : 1399,
    "minY" : 232,
    "maxY" : 300,
    "prop" : {
      "x" : 1357,
      "y" : 269,
      "width" : 41,
      "height" : 31
    },
    "textPosition" : {
      "x" : 1361,
      "y" : 274
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1393,
          "y" : 274
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1393,
          "y" : 274
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 128842,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 1370,
          "y" : 266
        },
        "to" : {
          "x" : 1355,
          "y" : 232
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 1364,
          "y" : 261
        },
        "b" : {
          "x" : 1370,
          "y" : 266
        },
        "c" : {
          "x" : 1371,
          "y" : 258
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 1371,
          "y" : 258
        }
      }
    } ]
  }, {
    "id" : 128848,
    "reactomeId" : 29372,
    "displayName" : "Pi",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 1432,
      "y" : 283
    },
    "minX" : 1355,
    "maxX" : 1449,
    "minY" : 232,
    "maxY" : 298,
    "prop" : {
      "x" : 1416,
      "y" : 268,
      "width" : 32,
      "height" : 30
    },
    "textPosition" : {
      "x" : 1422,
      "y" : 272
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1443,
          "y" : 273
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1443,
          "y" : 273
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 128842,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 1413,
          "y" : 272
        },
        "to" : {
          "x" : 1355,
          "y" : 232
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 1405,
          "y" : 271
        },
        "b" : {
          "x" : 1413,
          "y" : 272
        },
        "c" : {
          "x" : 1410,
          "y" : 265
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 1410,
          "y" : 265
        }
      }
    } ]
  }, {
    "id" : 128851,
    "reactomeId" : 29586,
    "displayName" : "FUMA",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 1530,
      "y" : 283
    },
    "minX" : 1502,
    "maxX" : 1559,
    "minY" : 231,
    "maxY" : 298,
    "prop" : {
      "x" : 1502,
      "y" : 268,
      "width" : 56,
      "height" : 30
    },
    "textPosition" : {
      "x" : 1509,
      "y" : 272
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1553,
          "y" : 273
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1553,
          "y" : 273
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 128849,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 1528,
          "y" : 265
        },
        "to" : {
          "x" : 1525,
          "y" : 231
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 1523,
          "y" : 258
        },
        "b" : {
          "x" : 1528,
          "y" : 265
        },
        "c" : {
          "x" : 1531,
          "y" : 258
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 1531,
          "y" : 258
        }
      }
    } ]
  }, {
    "id" : 128850,
    "reactomeId" : 111409,
    "displayName" : "AICAR",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 1588,
      "y" : 232
    },
    "minX" : 1525,
    "maxX" : 1643,
    "minY" : 216,
    "maxY" : 247,
    "prop" : {
      "x" : 1560,
      "y" : 217,
      "width" : 56,
      "height" : 30
    },
    "textPosition" : {
      "x" : 1566,
      "y" : 221
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1611,
          "y" : 222
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1611,
          "y" : 222
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 128849,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 1557,
          "y" : 231
        },
        "to" : {
          "x" : 1525,
          "y" : 231
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 1550,
          "y" : 235
        },
        "b" : {
          "x" : 1557,
          "y" : 231
        },
        "c" : {
          "x" : 1550,
          "y" : 227
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 1550,
          "y" : 227
        }
      }
    }, {
      "edgeId" : 128884,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1619,
          "y" : 230
        },
        "to" : {
          "x" : 1643,
          "y" : 230
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 128852,
    "reactomeId" : 10735666,
    "displayName" : "ADSL tetramer",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 1494,
      "y" : 178
    },
    "minX" : 1431,
    "maxX" : 1564,
    "minY" : 161,
    "maxY" : 224,
    "prop" : {
      "x" : 1431,
      "y" : 167,
      "width" : 127,
      "height" : 22
    },
    "textPosition" : {
      "x" : 1445,
      "y" : 168
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1558,
          "y" : 167
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1558,
          "y" : 167
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 128849,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 1494,
          "y" : 192
        },
        "to" : {
          "x" : 1496,
          "y" : 216
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 1496,
          "y" : 220
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1496,
          "y" : 220
        }
      }
    } ]
  }, {
    "id" : 128855,
    "reactomeId" : 113592,
    "displayName" : "ATP",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 80,
      "y" : 694
    },
    "minX" : 60,
    "maxX" : 118,
    "minY" : 641,
    "maxY" : 709,
    "prop" : {
      "x" : 60,
      "y" : 679,
      "width" : 40,
      "height" : 30
    },
    "textPosition" : {
      "x" : 64,
      "y" : 683
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 95,
          "y" : 684
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 95,
          "y" : 684
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 128853,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 90,
          "y" : 676
        },
        "to" : {
          "x" : 118,
          "y" : 641
        }
      } ],
      "stoichiometry" : {
        "value" : 2,
        "shape" : {
          "a" : {
            "x" : 98,
            "y" : 652
          },
          "b" : {
            "x" : 110,
            "y" : 664
          },
          "type" : "BOX",
          "empty" : true,
          "centre" : {
            "x" : 104,
            "y" : 658
          }
        }
      }
    } ]
  }, {
    "id" : 128854,
    "reactomeId" : 29356,
    "displayName" : "H2O",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 55,
      "y" : 657
    },
    "minX" : 31,
    "maxX" : 118,
    "minY" : 641,
    "maxY" : 672,
    "prop" : {
      "x" : 31,
      "y" : 642,
      "width" : 48,
      "height" : 30
    },
    "textPosition" : {
      "x" : 38,
      "y" : 646
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 74,
          "y" : 647
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 74,
          "y" : 647
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 128853,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 82,
          "y" : 650
        },
        "to" : {
          "x" : 118,
          "y" : 641
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ],
    "trivial" : true
  }, {
    "id" : 128857,
    "reactomeId" : 29472,
    "displayName" : "L-Gln",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 91,
      "y" : 568
    },
    "minX" : 63,
    "maxX" : 120,
    "minY" : 552,
    "maxY" : 641,
    "prop" : {
      "x" : 63,
      "y" : 553,
      "width" : 56,
      "height" : 30
    },
    "textPosition" : {
      "x" : 72,
      "y" : 557
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 114,
          "y" : 558
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 114,
          "y" : 558
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 128853,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 96,
          "y" : 586
        },
        "to" : {
          "x" : 118,
          "y" : 641
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 128856,
    "reactomeId" : 111627,
    "displayName" : "HCO3-",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 55,
      "y" : 610
    },
    "minX" : 23,
    "maxX" : 118,
    "minY" : 594,
    "maxY" : 641,
    "prop" : {
      "x" : 23,
      "y" : 595,
      "width" : 64,
      "height" : 30
    },
    "textPosition" : {
      "x" : 32,
      "y" : 599
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 82,
          "y" : 600
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 82,
          "y" : 600
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 128853,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 85,
          "y" : 628
        },
        "to" : {
          "x" : 118,
          "y" : 641
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 128859,
    "reactomeId" : 29370,
    "displayName" : "ADP",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 234,
      "y" : 720
    },
    "minX" : 184,
    "maxX" : 256,
    "minY" : 642,
    "maxY" : 736,
    "prop" : {
      "x" : 214,
      "y" : 705,
      "width" : 41,
      "height" : 31
    },
    "textPosition" : {
      "x" : 218,
      "y" : 710
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 250,
          "y" : 710
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 250,
          "y" : 710
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 128853,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 224,
          "y" : 702
        },
        "to" : {
          "x" : 184,
          "y" : 642
        }
      } ],
      "stoichiometry" : {
        "value" : 2,
        "shape" : {
          "a" : {
            "x" : 198,
            "y" : 666
          },
          "b" : {
            "x" : 210,
            "y" : 678
          },
          "type" : "BOX",
          "empty" : true,
          "centre" : {
            "x" : 204,
            "y" : 672
          }
        }
      },
      "endShape" : {
        "a" : {
          "x" : 217,
          "y" : 698
        },
        "b" : {
          "x" : 224,
          "y" : 702
        },
        "c" : {
          "x" : 223,
          "y" : 694
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 223,
          "y" : 694
        }
      }
    } ]
  }, {
    "id" : 128858,
    "reactomeId" : 111647,
    "displayName" : "CAP",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 258,
      "y" : 643
    },
    "minX" : 184,
    "maxX" : 326,
    "minY" : 627,
    "maxY" : 658,
    "prop" : {
      "x" : 238,
      "y" : 628,
      "width" : 40,
      "height" : 30
    },
    "textPosition" : {
      "x" : 242,
      "y" : 632
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 273,
          "y" : 633
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 273,
          "y" : 633
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 128853,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 235,
          "y" : 642
        },
        "to" : {
          "x" : 184,
          "y" : 642
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 228,
          "y" : 646
        },
        "b" : {
          "x" : 235,
          "y" : 642
        },
        "c" : {
          "x" : 228,
          "y" : 638
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 228,
          "y" : 638
        }
      }
    }, {
      "edgeId" : 128863,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 281,
          "y" : 643
        },
        "to" : {
          "x" : 326,
          "y" : 643
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 128861,
    "reactomeId" : 29404,
    "displayName" : "L-Glu",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 149,
      "y" : 709
    },
    "minX" : 121,
    "maxX" : 184,
    "minY" : 642,
    "maxY" : 724,
    "prop" : {
      "x" : 121,
      "y" : 694,
      "width" : 56,
      "height" : 30
    },
    "textPosition" : {
      "x" : 130,
      "y" : 698
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 172,
          "y" : 699
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 172,
          "y" : 699
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 128853,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 156,
          "y" : 691
        },
        "to" : {
          "x" : 184,
          "y" : 642
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 156,
          "y" : 683
        },
        "b" : {
          "x" : 156,
          "y" : 691
        },
        "c" : {
          "x" : 163,
          "y" : 687
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 163,
          "y" : 687
        }
      }
    } ]
  }, {
    "id" : 128860,
    "reactomeId" : 29372,
    "displayName" : "Pi",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 191,
      "y" : 744
    },
    "minX" : 175,
    "maxX" : 208,
    "minY" : 642,
    "maxY" : 759,
    "prop" : {
      "x" : 175,
      "y" : 729,
      "width" : 32,
      "height" : 30
    },
    "textPosition" : {
      "x" : 181,
      "y" : 733
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 202,
          "y" : 734
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 202,
          "y" : 734
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 128853,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 189,
          "y" : 726
        },
        "to" : {
          "x" : 184,
          "y" : 642
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 185,
          "y" : 719
        },
        "b" : {
          "x" : 189,
          "y" : 726
        },
        "c" : {
          "x" : 193,
          "y" : 719
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 193,
          "y" : 719
        }
      }
    } ]
  }, {
    "id" : 128862,
    "reactomeId" : 419448,
    "displayName" : "CAD hexamer",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 352,
      "y" : 587
    },
    "minX" : 152,
    "maxX" : 606,
    "minY" : 570,
    "maxY" : 637,
    "prop" : {
      "x" : 297,
      "y" : 576,
      "width" : 111,
      "height" : 22
    },
    "textPosition" : {
      "x" : 307,
      "y" : 577
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 408,
          "y" : 576
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 408,
          "y" : 576
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 128867,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 411,
          "y" : 588
        },
        "to" : {
          "x" : 600,
          "y" : 593
        }
      }, {
        "from" : {
          "x" : 600,
          "y" : 593
        },
        "to" : {
          "x" : 602,
          "y" : 629
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 602,
          "y" : 633
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 602,
          "y" : 633
        }
      }
    }, {
      "edgeId" : 128853,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 294,
          "y" : 588
        },
        "to" : {
          "x" : 157,
          "y" : 591
        }
      }, {
        "from" : {
          "x" : 157,
          "y" : 591
        },
        "to" : {
          "x" : 156,
          "y" : 626
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 156,
          "y" : 630
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 156,
          "y" : 630
        }
      }
    }, {
      "edgeId" : 128863,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 351,
          "y" : 601
        },
        "to" : {
          "x" : 350,
          "y" : 627
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 350,
          "y" : 631
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 350,
          "y" : 631
        }
      }
    } ]
  }, {
    "id" : 128865,
    "reactomeId" : 111628,
    "displayName" : "N-carb-L-Asp",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 481,
      "y" : 643
    },
    "minX" : 386,
    "maxX" : 570,
    "minY" : 627,
    "maxY" : 658,
    "prop" : {
      "x" : 426,
      "y" : 628,
      "width" : 111,
      "height" : 30
    },
    "textPosition" : {
      "x" : 438,
      "y" : 632
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 532,
          "y" : 633
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 532,
          "y" : 633
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 128867,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 540,
          "y" : 643
        },
        "to" : {
          "x" : 570,
          "y" : 644
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 128863,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 423,
          "y" : 644
        },
        "to" : {
          "x" : 386,
          "y" : 645
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 416,
          "y" : 648
        },
        "b" : {
          "x" : 423,
          "y" : 644
        },
        "c" : {
          "x" : 416,
          "y" : 640
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 416,
          "y" : 640
        }
      }
    } ]
  }, {
    "id" : 128864,
    "reactomeId" : 29448,
    "displayName" : "L-Asp",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 315,
      "y" : 704
    },
    "minX" : 287,
    "maxX" : 344,
    "minY" : 643,
    "maxY" : 719,
    "prop" : {
      "x" : 287,
      "y" : 689,
      "width" : 56,
      "height" : 30
    },
    "textPosition" : {
      "x" : 294,
      "y" : 693
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 338,
          "y" : 694
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 338,
          "y" : 694
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 128863,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 317,
          "y" : 686
        },
        "to" : {
          "x" : 326,
          "y" : 643
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 128866,
    "reactomeId" : 29372,
    "displayName" : "Pi",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 396,
      "y" : 698
    },
    "minX" : 380,
    "maxX" : 413,
    "minY" : 645,
    "maxY" : 713,
    "prop" : {
      "x" : 380,
      "y" : 683,
      "width" : 32,
      "height" : 30
    },
    "textPosition" : {
      "x" : 386,
      "y" : 687
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 407,
          "y" : 688
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 407,
          "y" : 688
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 128863,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 393,
          "y" : 680
        },
        "to" : {
          "x" : 386,
          "y" : 645
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 388,
          "y" : 674
        },
        "b" : {
          "x" : 393,
          "y" : 680
        },
        "c" : {
          "x" : 396,
          "y" : 672
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 396,
          "y" : 672
        }
      }
    } ]
  }, {
    "id" : 128869,
    "reactomeId" : 29356,
    "displayName" : "H2O",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 659,
      "y" : 698
    },
    "minX" : 635,
    "maxX" : 684,
    "minY" : 645,
    "maxY" : 713,
    "prop" : {
      "x" : 635,
      "y" : 683,
      "width" : 48,
      "height" : 30
    },
    "textPosition" : {
      "x" : 642,
      "y" : 687
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 678,
          "y" : 688
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 678,
          "y" : 688
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 128867,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 653,
          "y" : 680
        },
        "to" : {
          "x" : 638,
          "y" : 645
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 647,
          "y" : 675
        },
        "b" : {
          "x" : 653,
          "y" : 680
        },
        "c" : {
          "x" : 654,
          "y" : 672
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 654,
          "y" : 672
        }
      }
    } ],
    "trivial" : true
  }, {
    "id" : 128868,
    "reactomeId" : 70106,
    "displayName" : "H+",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 538,
      "y" : 695
    },
    "minX" : 518,
    "maxX" : 570,
    "minY" : 644,
    "maxY" : 710,
    "prop" : {
      "x" : 518,
      "y" : 680,
      "width" : 40,
      "height" : 30
    },
    "textPosition" : {
      "x" : 524,
      "y" : 684
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 553,
          "y" : 685
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 553,
          "y" : 685
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 128867,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 547,
          "y" : 677
        },
        "to" : {
          "x" : 570,
          "y" : 644
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ],
    "trivial" : true
  }, {
    "id" : 128870,
    "reactomeId" : 76630,
    "displayName" : "(S)-DHO",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 718,
      "y" : 643
    },
    "minX" : 638,
    "maxX" : 802,
    "minY" : 619,
    "maxY" : 658,
    "prop" : {
      "x" : 674,
      "y" : 628,
      "width" : 88,
      "height" : 30
    },
    "textPosition" : {
      "x" : 689,
      "y" : 632
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 757,
          "y" : 633
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 757,
          "y" : 633
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 128867,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 671,
          "y" : 644
        },
        "to" : {
          "x" : 638,
          "y" : 645
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 664,
          "y" : 648
        },
        "b" : {
          "x" : 671,
          "y" : 644
        },
        "c" : {
          "x" : 664,
          "y" : 640
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 664,
          "y" : 640
        }
      }
    }, {
      "edgeId" : 128871,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 765,
          "y" : 630
        },
        "to" : {
          "x" : 802,
          "y" : 619
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 128873,
    "reactomeId" : 76632,
    "displayName" : "ORO",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 985,
      "y" : 643
    },
    "minX" : 913,
    "maxX" : 1086,
    "minY" : 619,
    "maxY" : 658,
    "prop" : {
      "x" : 957,
      "y" : 628,
      "width" : 56,
      "height" : 30
    },
    "textPosition" : {
      "x" : 968,
      "y" : 632
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1008,
          "y" : 633
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1008,
          "y" : 633
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 128871,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 954,
          "y" : 633
        },
        "to" : {
          "x" : 913,
          "y" : 619
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 946,
          "y" : 635
        },
        "b" : {
          "x" : 954,
          "y" : 633
        },
        "c" : {
          "x" : 949,
          "y" : 627
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 949,
          "y" : 627
        }
      }
    }, {
      "edgeId" : 128876,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1016,
          "y" : 643
        },
        "to" : {
          "x" : 1086,
          "y" : 643
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 128872,
    "reactomeId" : 73663,
    "displayName" : "CoQ",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 713,
      "y" : 562
    },
    "minX" : 689,
    "maxX" : 802,
    "minY" : 546,
    "maxY" : 619,
    "prop" : {
      "x" : 689,
      "y" : 547,
      "width" : 48,
      "height" : 30
    },
    "textPosition" : {
      "x" : 696,
      "y" : 551
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 732,
          "y" : 552
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 732,
          "y" : 552
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 128871,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 736,
          "y" : 580
        },
        "to" : {
          "x" : 802,
          "y" : 619
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 128875,
    "reactomeId" : 10735215,
    "displayName" : "DHODH:FMN",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 796,
      "y" : 559
    },
    "minX" : 767,
    "maxX" : 858,
    "minY" : 518,
    "maxY" : 615,
    "prop" : {
      "x" : 767,
      "y" : 543,
      "width" : 59,
      "height" : 33
    },
    "textPosition" : {
      "x" : 768,
      "y" : 541
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 826,
          "y" : 543
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 826,
          "y" : 543
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 128871,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 814,
          "y" : 579
        },
        "to" : {
          "x" : 851,
          "y" : 609
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 854,
          "y" : 611
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 854,
          "y" : 611
        }
      }
    }, {
      "edgeId" : 128921,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 802,
          "y" : 540
        },
        "to" : {
          "x" : 812,
          "y" : 518
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 128874,
    "reactomeId" : 76633,
    "displayName" : "QH2",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 991,
      "y" : 562
    },
    "minX" : 913,
    "maxX" : 1016,
    "minY" : 546,
    "maxY" : 619,
    "prop" : {
      "x" : 967,
      "y" : 547,
      "width" : 48,
      "height" : 30
    },
    "textPosition" : {
      "x" : 974,
      "y" : 551
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1010,
          "y" : 552
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1010,
          "y" : 552
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 128871,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 970,
          "y" : 580
        },
        "to" : {
          "x" : 913,
          "y" : 619
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 967,
          "y" : 587
        },
        "b" : {
          "x" : 970,
          "y" : 580
        },
        "c" : {
          "x" : 962,
          "y" : 581
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 962,
          "y" : 581
        }
      }
    } ]
  }, {
    "id" : 128877,
    "reactomeId" : 73566,
    "displayName" : "PRPP",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 1060,
      "y" : 607
    },
    "minX" : 1036,
    "maxX" : 1086,
    "minY" : 591,
    "maxY" : 643,
    "prop" : {
      "x" : 1036,
      "y" : 592,
      "width" : 48,
      "height" : 30
    },
    "textPosition" : {
      "x" : 1040,
      "y" : 596
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1079,
          "y" : 597
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1079,
          "y" : 597
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 128876,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1070,
          "y" : 625
        },
        "to" : {
          "x" : 1086,
          "y" : 643
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 128879,
    "reactomeId" : 111294,
    "displayName" : "PPi",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 1192,
      "y" : 525
    },
    "minX" : 1164,
    "maxX" : 1210,
    "minY" : 509,
    "maxY" : 642,
    "prop" : {
      "x" : 1175,
      "y" : 510,
      "width" : 34,
      "height" : 31
    },
    "textPosition" : {
      "x" : 1178,
      "y" : 515
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1204,
          "y" : 515
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1204,
          "y" : 515
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 128876,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 1188,
          "y" : 544
        },
        "to" : {
          "x" : 1164,
          "y" : 642
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 1190,
          "y" : 552
        },
        "b" : {
          "x" : 1188,
          "y" : 544
        },
        "c" : {
          "x" : 1182,
          "y" : 550
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 1182,
          "y" : 550
        }
      }
    } ]
  }, {
    "id" : 128878,
    "reactomeId" : 111629,
    "displayName" : "OMP",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 1249,
      "y" : 643
    },
    "minX" : 1164,
    "maxX" : 1278,
    "minY" : 627,
    "maxY" : 658,
    "prop" : {
      "x" : 1221,
      "y" : 628,
      "width" : 56,
      "height" : 30
    },
    "textPosition" : {
      "x" : 1231,
      "y" : 632
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1272,
          "y" : 633
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1272,
          "y" : 633
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 128876,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 1218,
          "y" : 642
        },
        "to" : {
          "x" : 1164,
          "y" : 642
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 1211,
          "y" : 646
        },
        "b" : {
          "x" : 1218,
          "y" : 642
        },
        "c" : {
          "x" : 1211,
          "y" : 638
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 1211,
          "y" : 638
        }
      }
    }, {
      "edgeId" : 128881,
      "type" : "INPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 128880,
    "reactomeId" : 10735203,
    "displayName" : "UMPS dimer",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 1233,
      "y" : 720
    },
    "minX" : 1109,
    "maxX" : 1353,
    "minY" : 651,
    "maxY" : 731,
    "prop" : {
      "x" : 1182,
      "y" : 709,
      "width" : 103,
      "height" : 22
    },
    "textPosition" : {
      "x" : 1192,
      "y" : 710
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1285,
          "y" : 709
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1285,
          "y" : 709
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 128876,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 1193,
          "y" : 706
        },
        "to" : {
          "x" : 1113,
          "y" : 687
        }
      }, {
        "from" : {
          "x" : 1113,
          "y" : 687
        },
        "to" : {
          "x" : 1113,
          "y" : 659
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 1113,
          "y" : 655
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1113,
          "y" : 655
        }
      }
    }, {
      "edgeId" : 128881,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 1274,
          "y" : 706
        },
        "to" : {
          "x" : 1349,
          "y" : 689
        }
      }, {
        "from" : {
          "x" : 1349,
          "y" : 689
        },
        "to" : {
          "x" : 1349,
          "y" : 659
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 1349,
          "y" : 655
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1349,
          "y" : 655
        }
      }
    } ]
  }, {
    "id" : 128883,
    "reactomeId" : 113528,
    "displayName" : "CO2",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 1406,
      "y" : 688
    },
    "minX" : 1381,
    "maxX" : 1431,
    "minY" : 643,
    "maxY" : 703,
    "prop" : {
      "x" : 1382,
      "y" : 673,
      "width" : 48,
      "height" : 30
    },
    "textPosition" : {
      "x" : 1389,
      "y" : 677
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1425,
          "y" : 678
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1425,
          "y" : 678
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 128881,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 1397,
          "y" : 670
        },
        "to" : {
          "x" : 1381,
          "y" : 643
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 1390,
          "y" : 666
        },
        "b" : {
          "x" : 1397,
          "y" : 670
        },
        "c" : {
          "x" : 1397,
          "y" : 662
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 1397,
          "y" : 662
        }
      }
    } ],
    "trivial" : true
  }, {
    "id" : 128882,
    "reactomeId" : 109402,
    "displayName" : "UMP",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 1443,
      "y" : 643
    },
    "minX" : 1381,
    "maxX" : 1468,
    "minY" : 627,
    "maxY" : 658,
    "prop" : {
      "x" : 1419,
      "y" : 628,
      "width" : 48,
      "height" : 30
    },
    "textPosition" : {
      "x" : 1425,
      "y" : 632
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1462,
          "y" : 633
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1462,
          "y" : 633
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 128881,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 1416,
          "y" : 643
        },
        "to" : {
          "x" : 1381,
          "y" : 643
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 1409,
          "y" : 647
        },
        "b" : {
          "x" : 1416,
          "y" : 643
        },
        "c" : {
          "x" : 1409,
          "y" : 639
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 1409,
          "y" : 639
        }
      }
    } ]
  }, {
    "id" : 128885,
    "reactomeId" : 419151,
    "displayName" : "10-formyl-THF",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 1627,
      "y" : 283
    },
    "minX" : 1583,
    "maxX" : 1673,
    "minY" : 230,
    "maxY" : 301,
    "prop" : {
      "x" : 1583,
      "y" : 265,
      "width" : 89,
      "height" : 36
    },
    "textPosition" : {
      "x" : 1593,
      "y" : 265
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1667,
          "y" : 270
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1667,
          "y" : 270
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 128884,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1632,
          "y" : 262
        },
        "to" : {
          "x" : 1643,
          "y" : 230
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 128887,
    "reactomeId" : 111355,
    "displayName" : "THF",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 1723,
      "y" : 283
    },
    "minX" : 1689,
    "maxX" : 1744,
    "minY" : 233,
    "maxY" : 298,
    "prop" : {
      "x" : 1703,
      "y" : 268,
      "width" : 40,
      "height" : 30
    },
    "textPosition" : {
      "x" : 1707,
      "y" : 272
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1738,
          "y" : 273
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1738,
          "y" : 273
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 128884,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 1712,
          "y" : 265
        },
        "to" : {
          "x" : 1689,
          "y" : 233
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 1705,
          "y" : 262
        },
        "b" : {
          "x" : 1712,
          "y" : 265
        },
        "c" : {
          "x" : 1711,
          "y" : 257
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 1711,
          "y" : 257
        }
      }
    } ]
  }, {
    "id" : 128886,
    "reactomeId" : 111427,
    "displayName" : "FAICAR",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 1744,
      "y" : 234
    },
    "minX" : 1689,
    "maxX" : 1777,
    "minY" : 218,
    "maxY" : 249,
    "prop" : {
      "x" : 1712,
      "y" : 219,
      "width" : 64,
      "height" : 30
    },
    "textPosition" : {
      "x" : 1719,
      "y" : 223
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1771,
          "y" : 224
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1771,
          "y" : 224
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 128884,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 1709,
          "y" : 233
        },
        "to" : {
          "x" : 1689,
          "y" : 233
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 1702,
          "y" : 237
        },
        "b" : {
          "x" : 1709,
          "y" : 233
        },
        "c" : {
          "x" : 1702,
          "y" : 229
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 1702,
          "y" : 229
        }
      }
    }, {
      "edgeId" : 128889,
      "type" : "INPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 128888,
    "reactomeId" : 10735655,
    "displayName" : "ATIC dimer",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 1733,
      "y" : 184
    },
    "minX" : 1660,
    "maxX" : 1808,
    "minY" : 167,
    "maxY" : 225,
    "prop" : {
      "x" : 1685,
      "y" : 173,
      "width" : 96,
      "height" : 22
    },
    "textPosition" : {
      "x" : 1696,
      "y" : 174
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1781,
          "y" : 173
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1781,
          "y" : 173
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 128884,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 1682,
          "y" : 182
        },
        "to" : {
          "x" : 1664,
          "y" : 182
        }
      }, {
        "from" : {
          "x" : 1664,
          "y" : 182
        },
        "to" : {
          "x" : 1664,
          "y" : 215
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 1664,
          "y" : 219
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1664,
          "y" : 219
        }
      }
    }, {
      "edgeId" : 128889,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 1784,
          "y" : 184
        },
        "to" : {
          "x" : 1802,
          "y" : 185
        }
      }, {
        "from" : {
          "x" : 1802,
          "y" : 185
        },
        "to" : {
          "x" : 1803,
          "y" : 217
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 1804,
          "y" : 221
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1804,
          "y" : 221
        }
      }
    } ]
  }, {
    "id" : 128890,
    "reactomeId" : 29356,
    "displayName" : "H2O",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 1787,
      "y" : 275
    },
    "minX" : 1763,
    "maxX" : 1836,
    "minY" : 234,
    "maxY" : 290,
    "prop" : {
      "x" : 1763,
      "y" : 260,
      "width" : 48,
      "height" : 30
    },
    "textPosition" : {
      "x" : 1770,
      "y" : 264
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1806,
          "y" : 265
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1806,
          "y" : 265
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 128889,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 1804,
          "y" : 257
        },
        "to" : {
          "x" : 1836,
          "y" : 234
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 1807,
          "y" : 250
        },
        "b" : {
          "x" : 1804,
          "y" : 257
        },
        "c" : {
          "x" : 1812,
          "y" : 256
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 1812,
          "y" : 256
        }
      }
    } ],
    "trivial" : true
  }, {
    "id" : 128893,
    "reactomeId" : 29360,
    "displayName" : "NAD+",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 1644,
      "y" : 377
    },
    "minX" : 1612,
    "maxX" : 1711,
    "minY" : 361,
    "maxY" : 392,
    "prop" : {
      "x" : 1612,
      "y" : 362,
      "width" : 64,
      "height" : 30
    },
    "textPosition" : {
      "x" : 1622,
      "y" : 366
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1671,
          "y" : 367
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1671,
          "y" : 367
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 128891,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1679,
          "y" : 372
        },
        "to" : {
          "x" : 1711,
          "y" : 368
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 128892,
    "reactomeId" : 29356,
    "displayName" : "H2O",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 1664,
      "y" : 342
    },
    "minX" : 1640,
    "maxX" : 1711,
    "minY" : 326,
    "maxY" : 368,
    "prop" : {
      "x" : 1640,
      "y" : 327,
      "width" : 48,
      "height" : 30
    },
    "textPosition" : {
      "x" : 1647,
      "y" : 331
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1683,
          "y" : 332
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1683,
          "y" : 332
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 128891,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1691,
          "y" : 355
        },
        "to" : {
          "x" : 1711,
          "y" : 368
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ],
    "trivial" : true
  }, {
    "id" : 128895,
    "reactomeId" : 111584,
    "displayName" : "XMP",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 1712,
      "y" : 501
    },
    "minX" : 1688,
    "maxX" : 1761,
    "minY" : 411,
    "maxY" : 568,
    "prop" : {
      "x" : 1688,
      "y" : 486,
      "width" : 48,
      "height" : 30
    },
    "textPosition" : {
      "x" : 1695,
      "y" : 490
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1731,
          "y" : 491
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1731,
          "y" : 491
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 128898,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1712,
          "y" : 519
        },
        "to" : {
          "x" : 1713,
          "y" : 568
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 128891,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 1711,
          "y" : 483
        },
        "to" : {
          "x" : 1711,
          "y" : 446
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 1707,
          "y" : 476
        },
        "b" : {
          "x" : 1711,
          "y" : 483
        },
        "c" : {
          "x" : 1715,
          "y" : 476
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 1715,
          "y" : 476
        }
      }
    }, {
      "edgeId" : 128891,
      "type" : "INHIBITOR",
      "segments" : [ {
        "from" : {
          "x" : 1720,
          "y" : 483
        },
        "to" : {
          "x" : 1761,
          "y" : 415
        }
      }, {
        "from" : {
          "x" : 1761,
          "y" : 415
        },
        "to" : {
          "x" : 1720,
          "y" : 415
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 1720,
          "y" : 419
        },
        "b" : {
          "x" : 1720,
          "y" : 411
        },
        "c" : {
          "x" : 1720,
          "y" : 415
        },
        "type" : "STOP",
        "centre" : {
          "x" : 1720,
          "y" : 415
        }
      }
    } ]
  }, {
    "id" : 128894,
    "reactomeId" : 73473,
    "displayName" : "NADH",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 1620,
      "y" : 457
    },
    "minX" : 1592,
    "maxX" : 1711,
    "minY" : 441,
    "maxY" : 472,
    "prop" : {
      "x" : 1592,
      "y" : 442,
      "width" : 56,
      "height" : 30
    },
    "textPosition" : {
      "x" : 1598,
      "y" : 446
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1643,
          "y" : 447
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1643,
          "y" : 447
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 128891,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 1651,
          "y" : 453
        },
        "to" : {
          "x" : 1711,
          "y" : 446
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 1657,
          "y" : 448
        },
        "b" : {
          "x" : 1651,
          "y" : 453
        },
        "c" : {
          "x" : 1658,
          "y" : 456
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 1658,
          "y" : 456
        }
      }
    } ]
  }, {
    "id" : 128897,
    "reactomeId" : 421214,
    "displayName" : "IMPDH2",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "EntitySet",
    "position" : {
      "x" : 1529,
      "y" : 381
    },
    "minX" : 1409,
    "maxX" : 1703,
    "minY" : 363,
    "maxY" : 420,
    "prop" : {
      "x" : 1485,
      "y" : 363,
      "width" : 88,
      "height" : 36
    },
    "textPosition" : {
      "x" : 1501,
      "y" : 370
    },
    "connectors" : [ {
      "edgeId" : 128918,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1479,
          "y" : 395
        },
        "to" : {
          "x" : 1409,
          "y" : 420
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 128891,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 1579,
          "y" : 389
        },
        "to" : {
          "x" : 1695,
          "y" : 412
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 1699,
          "y" : 413
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1699,
          "y" : 413
        }
      }
    } ]
  }, {
    "id" : 128896,
    "reactomeId" : 70106,
    "displayName" : "H+",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 1654,
      "y" : 490
    },
    "minX" : 1634,
    "maxX" : 1711,
    "minY" : 446,
    "maxY" : 505,
    "prop" : {
      "x" : 1634,
      "y" : 475,
      "width" : 40,
      "height" : 30
    },
    "textPosition" : {
      "x" : 1640,
      "y" : 479
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1669,
          "y" : 480
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1669,
          "y" : 480
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 128891,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 1673,
          "y" : 472
        },
        "to" : {
          "x" : 1711,
          "y" : 446
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 1676,
          "y" : 465
        },
        "b" : {
          "x" : 1673,
          "y" : 472
        },
        "c" : {
          "x" : 1681,
          "y" : 471
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 1681,
          "y" : 471
        }
      }
    } ],
    "trivial" : true
  }, {
    "id" : 128899,
    "reactomeId" : 29356,
    "displayName" : "H2O",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 1596,
      "y" : 562
    },
    "minX" : 1572,
    "maxX" : 1713,
    "minY" : 546,
    "maxY" : 577,
    "prop" : {
      "x" : 1572,
      "y" : 547,
      "width" : 48,
      "height" : 30
    },
    "textPosition" : {
      "x" : 1579,
      "y" : 551
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1615,
          "y" : 552
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1615,
          "y" : 552
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 128898,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1623,
          "y" : 563
        },
        "to" : {
          "x" : 1713,
          "y" : 568
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ],
    "trivial" : true
  }, {
    "id" : 128901,
    "reactomeId" : 29472,
    "displayName" : "L-Gln",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 1653,
      "y" : 537
    },
    "minX" : 1625,
    "maxX" : 1713,
    "minY" : 521,
    "maxY" : 568,
    "prop" : {
      "x" : 1625,
      "y" : 522,
      "width" : 56,
      "height" : 30
    },
    "textPosition" : {
      "x" : 1634,
      "y" : 526
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1676,
          "y" : 527
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1676,
          "y" : 527
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 128898,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1684,
          "y" : 551
        },
        "to" : {
          "x" : 1713,
          "y" : 568
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 128900,
    "reactomeId" : 113592,
    "displayName" : "ATP",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 1662,
      "y" : 592
    },
    "minX" : 1642,
    "maxX" : 1713,
    "minY" : 568,
    "maxY" : 607,
    "prop" : {
      "x" : 1642,
      "y" : 577,
      "width" : 40,
      "height" : 30
    },
    "textPosition" : {
      "x" : 1646,
      "y" : 581
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1677,
          "y" : 582
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1677,
          "y" : 582
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 128898,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1685,
          "y" : 582
        },
        "to" : {
          "x" : 1713,
          "y" : 568
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 128903,
    "reactomeId" : 29404,
    "displayName" : "L-Glu",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 1645,
      "y" : 726
    },
    "minX" : 1617,
    "maxX" : 1711,
    "minY" : 653,
    "maxY" : 741,
    "prop" : {
      "x" : 1617,
      "y" : 711,
      "width" : 56,
      "height" : 30
    },
    "textPosition" : {
      "x" : 1626,
      "y" : 715
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1668,
          "y" : 716
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1668,
          "y" : 716
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 128898,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 1658,
          "y" : 708
        },
        "to" : {
          "x" : 1711,
          "y" : 653
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 1660,
          "y" : 700
        },
        "b" : {
          "x" : 1658,
          "y" : 708
        },
        "c" : {
          "x" : 1666,
          "y" : 706
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 1666,
          "y" : 706
        }
      }
    } ]
  }, {
    "id" : 128902,
    "reactomeId" : 76577,
    "displayName" : "AMP",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 1577,
      "y" : 656
    },
    "minX" : 1553,
    "maxX" : 1711,
    "minY" : 640,
    "maxY" : 671,
    "prop" : {
      "x" : 1553,
      "y" : 641,
      "width" : 48,
      "height" : 30
    },
    "textPosition" : {
      "x" : 1560,
      "y" : 645
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1596,
          "y" : 646
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1596,
          "y" : 646
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 128898,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 1604,
          "y" : 655
        },
        "to" : {
          "x" : 1711,
          "y" : 653
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 1611,
          "y" : 651
        },
        "b" : {
          "x" : 1604,
          "y" : 655
        },
        "c" : {
          "x" : 1611,
          "y" : 659
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 1611,
          "y" : 659
        }
      }
    } ]
  }, {
    "id" : 128905,
    "reactomeId" : 421212,
    "displayName" : "GMPS",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 1766,
      "y" : 605
    },
    "minX" : 1721,
    "maxX" : 1796,
    "minY" : 588,
    "maxY" : 616,
    "prop" : {
      "x" : 1742,
      "y" : 594,
      "width" : 48,
      "height" : 22
    },
    "textPosition" : {
      "x" : 1744,
      "y" : 594
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1790,
          "y" : 594
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1790,
          "y" : 594
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 128898,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 1739,
          "y" : 605
        },
        "to" : {
          "x" : 1729,
          "y" : 605
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 1725,
          "y" : 605
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1725,
          "y" : 605
        }
      }
    } ]
  }, {
    "id" : 128904,
    "reactomeId" : 111294,
    "displayName" : "PPi",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 1578,
      "y" : 610
    },
    "minX" : 1561,
    "maxX" : 1711,
    "minY" : 594,
    "maxY" : 653,
    "prop" : {
      "x" : 1561,
      "y" : 595,
      "width" : 34,
      "height" : 31
    },
    "textPosition" : {
      "x" : 1564,
      "y" : 600
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1590,
          "y" : 600
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1590,
          "y" : 600
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 128898,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 1598,
          "y" : 615
        },
        "to" : {
          "x" : 1711,
          "y" : 653
        }
      } ],
      "stoichiometry" : {
        "value" : 2,
        "shape" : {
          "a" : {
            "x" : 1648,
            "y" : 628
          },
          "b" : {
            "x" : 1660,
            "y" : 640
          },
          "type" : "BOX",
          "empty" : true,
          "centre" : {
            "x" : 1654,
            "y" : 634
          }
        }
      },
      "endShape" : {
        "a" : {
          "x" : 1606,
          "y" : 613
        },
        "b" : {
          "x" : 1598,
          "y" : 615
        },
        "c" : {
          "x" : 1603,
          "y" : 621
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 1603,
          "y" : 621
        }
      }
    } ]
  }, {
    "id" : 128907,
    "reactomeId" : 29438,
    "displayName" : "GTP",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 1965,
      "y" : 283
    },
    "minX" : 1939,
    "maxX" : 1986,
    "minY" : 267,
    "maxY" : 337,
    "prop" : {
      "x" : 1945,
      "y" : 268,
      "width" : 40,
      "height" : 30
    },
    "textPosition" : {
      "x" : 1949,
      "y" : 272
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1980,
          "y" : 273
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1980,
          "y" : 273
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 128906,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1957,
          "y" : 301
        },
        "to" : {
          "x" : 1939,
          "y" : 337
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 128909,
    "reactomeId" : 29420,
    "displayName" : "GDP",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 1998,
      "y" : 469
    },
    "minX" : 1943,
    "maxX" : 2023,
    "minY" : 408,
    "maxY" : 484,
    "prop" : {
      "x" : 1974,
      "y" : 454,
      "width" : 48,
      "height" : 30
    },
    "textPosition" : {
      "x" : 1981,
      "y" : 458
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 2017,
          "y" : 459
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 2017,
          "y" : 459
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 128906,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 1971,
          "y" : 456
        },
        "to" : {
          "x" : 1943,
          "y" : 441
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 1963,
          "y" : 456
        },
        "b" : {
          "x" : 1971,
          "y" : 456
        },
        "c" : {
          "x" : 1967,
          "y" : 449
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 1967,
          "y" : 449
        }
      }
    }, {
      "edgeId" : 128906,
      "type" : "INHIBITOR",
      "segments" : [ {
        "from" : {
          "x" : 1985,
          "y" : 451
        },
        "to" : {
          "x" : 1948,
          "y" : 411
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 1945,
          "y" : 414
        },
        "b" : {
          "x" : 1951,
          "y" : 408
        },
        "c" : {
          "x" : 1948,
          "y" : 411
        },
        "type" : "STOP",
        "centre" : {
          "x" : 1948,
          "y" : 411
        }
      }
    } ]
  }, {
    "id" : 128908,
    "reactomeId" : 29448,
    "displayName" : "L-Asp",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 1875,
      "y" : 321
    },
    "minX" : 1847,
    "maxX" : 1939,
    "minY" : 305,
    "maxY" : 337,
    "prop" : {
      "x" : 1847,
      "y" : 306,
      "width" : 56,
      "height" : 30
    },
    "textPosition" : {
      "x" : 1854,
      "y" : 310
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1898,
          "y" : 311
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1898,
          "y" : 311
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 128906,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1906,
          "y" : 328
        },
        "to" : {
          "x" : 1939,
          "y" : 337
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 128911,
    "reactomeId" : 29372,
    "displayName" : "Pi",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 1896,
      "y" : 503
    },
    "minX" : 1880,
    "maxX" : 1943,
    "minY" : 441,
    "maxY" : 518,
    "prop" : {
      "x" : 1880,
      "y" : 488,
      "width" : 32,
      "height" : 30
    },
    "textPosition" : {
      "x" : 1886,
      "y" : 492
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1907,
          "y" : 493
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1907,
          "y" : 493
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 128906,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 1907,
          "y" : 485
        },
        "to" : {
          "x" : 1943,
          "y" : 441
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 1908,
          "y" : 477
        },
        "b" : {
          "x" : 1907,
          "y" : 485
        },
        "c" : {
          "x" : 1914,
          "y" : 482
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 1914,
          "y" : 482
        }
      }
    } ]
  }, {
    "id" : 128910,
    "reactomeId" : 35141,
    "displayName" : "ADS",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 1945,
      "y" : 509
    },
    "minX" : 1921,
    "maxX" : 2040,
    "minY" : 402,
    "maxY" : 524,
    "prop" : {
      "x" : 1921,
      "y" : 494,
      "width" : 48,
      "height" : 30
    },
    "textPosition" : {
      "x" : 1928,
      "y" : 498
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1964,
          "y" : 499
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1964,
          "y" : 499
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 128906,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 1944,
          "y" : 491
        },
        "to" : {
          "x" : 1943,
          "y" : 441
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 1940,
          "y" : 484
        },
        "b" : {
          "x" : 1944,
          "y" : 491
        },
        "c" : {
          "x" : 1948,
          "y" : 484
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 1948,
          "y" : 484
        }
      }
    }, {
      "edgeId" : 128906,
      "type" : "INHIBITOR",
      "segments" : [ {
        "from" : {
          "x" : 1972,
          "y" : 508
        },
        "to" : {
          "x" : 2040,
          "y" : 508
        }
      }, {
        "from" : {
          "x" : 2040,
          "y" : 508
        },
        "to" : {
          "x" : 2039,
          "y" : 426
        }
      }, {
        "from" : {
          "x" : 2039,
          "y" : 426
        },
        "to" : {
          "x" : 1951,
          "y" : 406
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 1950,
          "y" : 410
        },
        "b" : {
          "x" : 1952,
          "y" : 402
        },
        "c" : {
          "x" : 1951,
          "y" : 406
        },
        "type" : "STOP",
        "centre" : {
          "x" : 1951,
          "y" : 406
        }
      }
    }, {
      "edgeId" : 128915,
      "type" : "INPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 128913,
    "reactomeId" : 10738526,
    "displayName" : "ADSS, ADSSL1 dimers",
    "schemaClass" : "DefinedSet",
    "renderableClass" : "EntitySet",
    "position" : {
      "x" : 1829,
      "y" : 380
    },
    "minX" : 1766,
    "maxX" : 1934,
    "minY" : 362,
    "maxY" : 405,
    "prop" : {
      "x" : 1766,
      "y" : 362,
      "width" : 127,
      "height" : 36
    },
    "textPosition" : {
      "x" : 1779,
      "y" : 362
    },
    "connectors" : [ {
      "edgeId" : 128906,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 1899,
          "y" : 393
        },
        "to" : {
          "x" : 1926,
          "y" : 400
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 1930,
          "y" : 401
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1930,
          "y" : 401
        }
      }
    } ]
  }, {
    "id" : 128912,
    "reactomeId" : 70106,
    "displayName" : "H+",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 1872,
      "y" : 463
    },
    "minX" : 1852,
    "maxX" : 1943,
    "minY" : 441,
    "maxY" : 478,
    "prop" : {
      "x" : 1852,
      "y" : 448,
      "width" : 40,
      "height" : 30
    },
    "textPosition" : {
      "x" : 1858,
      "y" : 452
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1887,
          "y" : 453
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1887,
          "y" : 453
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 128906,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 1895,
          "y" : 456
        },
        "to" : {
          "x" : 1943,
          "y" : 441
        }
      } ],
      "stoichiometry" : {
        "value" : 2,
        "shape" : {
          "a" : {
            "x" : 1913,
            "y" : 442
          },
          "b" : {
            "x" : 1925,
            "y" : 454
          },
          "type" : "BOX",
          "empty" : true,
          "centre" : {
            "x" : 1919,
            "y" : 448
          }
        }
      },
      "endShape" : {
        "a" : {
          "x" : 1900,
          "y" : 450
        },
        "b" : {
          "x" : 1895,
          "y" : 456
        },
        "c" : {
          "x" : 1903,
          "y" : 458
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 1903,
          "y" : 458
        }
      }
    } ],
    "trivial" : true
  }, {
    "id" : 128914,
    "reactomeId" : 30014,
    "displayName" : "F1,6PP",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 2018,
      "y" : 363
    },
    "minX" : 1948,
    "maxX" : 2051,
    "minY" : 347,
    "maxY" : 404,
    "prop" : {
      "x" : 1986,
      "y" : 348,
      "width" : 64,
      "height" : 30
    },
    "textPosition" : {
      "x" : 1992,
      "y" : 352
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 2045,
          "y" : 353
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 2045,
          "y" : 353
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 128906,
      "type" : "INHIBITOR",
      "segments" : [ {
        "from" : {
          "x" : 1990,
          "y" : 381
        },
        "to" : {
          "x" : 1950,
          "y" : 400
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 1948,
          "y" : 396
        },
        "b" : {
          "x" : 1952,
          "y" : 404
        },
        "c" : {
          "x" : 1950,
          "y" : 400
        },
        "type" : "STOP",
        "centre" : {
          "x" : 1950,
          "y" : 400
        }
      }
    } ]
  }, {
    "id" : 128917,
    "reactomeId" : 10735666,
    "displayName" : "ADSL tetramer",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 2021,
      "y" : 574
    },
    "minX" : 1954,
    "maxX" : 2066,
    "minY" : 550,
    "maxY" : 593,
    "prop" : {
      "x" : 1983,
      "y" : 556,
      "width" : 77,
      "height" : 37
    },
    "textPosition" : {
      "x" : 1990,
      "y" : 558
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 2060,
          "y" : 556
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 2060,
          "y" : 556
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 128915,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 1980,
          "y" : 574
        },
        "to" : {
          "x" : 1962,
          "y" : 575
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 1958,
          "y" : 575
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1958,
          "y" : 575
        }
      }
    } ]
  }, {
    "id" : 128916,
    "reactomeId" : 29586,
    "displayName" : "FUMA",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 2022,
      "y" : 627
    },
    "minX" : 1946,
    "maxX" : 2051,
    "minY" : 611,
    "maxY" : 642,
    "prop" : {
      "x" : 1994,
      "y" : 612,
      "width" : 56,
      "height" : 30
    },
    "textPosition" : {
      "x" : 2001,
      "y" : 616
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 2045,
          "y" : 617
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 2045,
          "y" : 617
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 128915,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 1991,
          "y" : 622
        },
        "to" : {
          "x" : 1946,
          "y" : 616
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 1984,
          "y" : 625
        },
        "b" : {
          "x" : 1991,
          "y" : 622
        },
        "c" : {
          "x" : 1985,
          "y" : 617
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 1985,
          "y" : 617
        }
      }
    } ]
  }, {
    "id" : 128919,
    "reactomeId" : 9678719,
    "displayName" : "IMPDH inhibitors",
    "schemaClass" : "DefinedSet",
    "renderableClass" : "EntitySetDrug",
    "position" : {
      "x" : 1372,
      "y" : 353
    },
    "minX" : 1328,
    "maxX" : 1416,
    "minY" : 335,
    "maxY" : 420,
    "prop" : {
      "x" : 1328,
      "y" : 335,
      "width" : 88,
      "height" : 36
    },
    "textPosition" : {
      "x" : 1339,
      "y" : 335
    },
    "bgColor" : {
      "r" : 184,
      "g" : 154,
      "b" : 230
    },
    "fgColor" : {
      "r" : 161,
      "g" : 1,
      "b" : 2
    },
    "connectors" : [ {
      "edgeId" : 128918,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1381,
          "y" : 377
        },
        "to" : {
          "x" : 1409,
          "y" : 420
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 128920,
    "reactomeId" : 10735646,
    "displayName" : "IMPDH tetramers:IMPDH inhibitors",
    "schemaClass" : "Complex",
    "renderableClass" : "ComplexDrug",
    "position" : {
      "x" : 1515,
      "y" : 450
    },
    "minX" : 1467,
    "maxX" : 1569,
    "minY" : 412,
    "maxY" : 482,
    "prop" : {
      "x" : 1467,
      "y" : 418,
      "width" : 96,
      "height" : 64
    },
    "textPosition" : {
      "x" : 1478,
      "y" : 419
    },
    "bgColor" : {
      "r" : 184,
      "g" : 154,
      "b" : 230
    },
    "fgColor" : {
      "r" : 161,
      "g" : 1,
      "b" : 2
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1563,
          "y" : 418
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1563,
          "y" : 418
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 128918,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 128923,
    "reactomeId" : 10818350,
    "displayName" : "DHODH:FMN:DHODH inhibitors",
    "schemaClass" : "Complex",
    "renderableClass" : "ComplexDrug",
    "position" : {
      "x" : 896,
      "y" : 559
    },
    "minX" : 835,
    "maxX" : 964,
    "minY" : 535,
    "maxY" : 577,
    "prop" : {
      "x" : 835,
      "y" : 541,
      "width" : 123,
      "height" : 36
    },
    "textPosition" : {
      "x" : 839,
      "y" : 542
    },
    "bgColor" : {
      "r" : 184,
      "g" : 154,
      "b" : 230
    },
    "fgColor" : {
      "r" : 161,
      "g" : 1,
      "b" : 2
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 958,
          "y" : 541
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 958,
          "y" : 541
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 128921,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 128922,
    "reactomeId" : 9708729,
    "displayName" : "DHODH inhibitors",
    "schemaClass" : "CandidateSet",
    "renderableClass" : "EntitySetDrug",
    "position" : {
      "x" : 594,
      "y" : 518
    },
    "minX" : 550,
    "maxX" : 812,
    "minY" : 500,
    "maxY" : 536,
    "prop" : {
      "x" : 550,
      "y" : 500,
      "width" : 88,
      "height" : 36
    },
    "textPosition" : {
      "x" : 561,
      "y" : 500
    },
    "bgColor" : {
      "r" : 184,
      "g" : 154,
      "b" : 230
    },
    "fgColor" : {
      "r" : 161,
      "g" : 1,
      "b" : 2
    },
    "connectors" : [ {
      "edgeId" : 128921,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 644,
          "y" : 518
        },
        "to" : {
          "x" : 812,
          "y" : 518
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 128934,
    "reactomeId" : 10825297,
    "displayName" : "Pyrophosphate hydrolysis",
    "schemaClass" : "Pathway",
    "renderableClass" : "EncapsulatedNode",
    "position" : {
      "x" : 825,
      "y" : 368
    },
    "minX" : 763,
    "maxX" : 887,
    "minY" : 340,
    "maxY" : 396,
    "prop" : {
      "x" : 763,
      "y" : 340,
      "width" : 124,
      "height" : 56
    },
    "textPosition" : {
      "x" : 767,
      "y" : 346
    },
    "connectors" : [ ]
  } ],
  "edges" : [ {
    "id" : 128867,
    "reactomeId" : 419465,
    "displayName" : "N-carbamoyl L-aspartate + H+ <=> (S)-dihydroorotate + H2O",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 603,
      "y" : 645
    },
    "minX" : 570,
    "maxX" : 638,
    "minY" : 639,
    "maxY" : 651,
    "segments" : [ {
      "from" : {
        "x" : 570,
        "y" : 644
      },
      "to" : {
        "x" : 603,
        "y" : 645
      }
    }, {
      "from" : {
        "x" : 603,
        "y" : 645
      },
      "to" : {
        "x" : 638,
        "y" : 645
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 597,
        "y" : 639
      },
      "b" : {
        "x" : 609,
        "y" : 651
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 603,
        "y" : 645
      }
    },
    "inputs" : [ {
      "id" : 128868,
      "points" : [ {
        "x" : 547,
        "y" : 677
      } ]
    }, {
      "id" : 128865,
      "points" : [ {
        "x" : 540,
        "y" : 643
      } ]
    } ],
    "outputs" : [ {
      "id" : 128869,
      "points" : [ {
        "x" : 653,
        "y" : 680
      } ]
    }, {
      "id" : 128870,
      "points" : [ {
        "x" : 671,
        "y" : 644
      } ]
    } ],
    "catalysts" : [ {
      "id" : 128862,
      "points" : [ {
        "x" : 411,
        "y" : 588
      }, {
        "x" : 600,
        "y" : 593
      } ]
    } ]
  }, {
    "id" : 128803,
    "reactomeId" : 10738494,
    "displayName" : "Formation of phosphoribosyl pyrophosphate amidotransferase tetramer",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 182,
      "y" : 100
    },
    "minX" : 159,
    "maxX" : 188,
    "minY" : 62,
    "maxY" : 169,
    "reactionType" : "binding",
    "segments" : [ {
      "from" : {
        "x" : 159,
        "y" : 169
      },
      "to" : {
        "x" : 182,
        "y" : 100
      }
    }, {
      "from" : {
        "x" : 182,
        "y" : 100
      },
      "to" : {
        "x" : 163,
        "y" : 62
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 170,
        "y" : 66
      },
      "b" : {
        "x" : 163,
        "y" : 62
      },
      "c" : {
        "x" : 163,
        "y" : 70
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 163,
        "y" : 70
      }
    },
    "reactionShape" : {
      "c" : {
        "x" : 182,
        "y" : 100
      },
      "r" : 5,
      "type" : "CIRCLE",
      "centre" : {
        "x" : 182,
        "y" : 100
      }
    },
    "inputs" : [ {
      "id" : 128804,
      "stoichiometry" : 2
    } ],
    "outputs" : [ {
      "id" : 128805
    } ],
    "activators" : [ {
      "id" : 128806,
      "points" : [ {
        "x" : 1893,
        "y" : 220
      }, {
        "x" : 1856,
        "y" : 110
      } ]
    }, {
      "id" : 128807,
      "points" : [ {
        "x" : 1975,
        "y" : 673
      }, {
        "x" : 2090,
        "y" : 673
      }, {
        "x" : 2086,
        "y" : 330
      }, {
        "x" : 1890,
        "y" : 88
      } ]
    }, {
      "id" : 128808,
      "points" : [ {
        "x" : 1739,
        "y" : 701
      }, {
        "x" : 2115,
        "y" : 705
      }, {
        "x" : 2115,
        "y" : 329
      }, {
        "x" : 1925,
        "y" : 66
      } ]
    } ]
  }, {
    "id" : 128898,
    "reactomeId" : 421218,
    "displayName" : "xanthosine 5'-monophosphate (XMP) + L-glutamine + ATP + H2O => guanosine 5'-monophosphate (GMP) + L-glutamate + adenosine 5'-monophosphate (AMP) + pyrophosphate",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 1713,
      "y" : 605
    },
    "minX" : 1707,
    "maxX" : 1719,
    "minY" : 568,
    "maxY" : 653,
    "segments" : [ {
      "from" : {
        "x" : 1713,
        "y" : 568
      },
      "to" : {
        "x" : 1713,
        "y" : 605
      }
    }, {
      "from" : {
        "x" : 1713,
        "y" : 605
      },
      "to" : {
        "x" : 1711,
        "y" : 653
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 1707,
        "y" : 599
      },
      "b" : {
        "x" : 1719,
        "y" : 611
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 1713,
        "y" : 605
      }
    },
    "inputs" : [ {
      "id" : 128899,
      "points" : [ {
        "x" : 1623,
        "y" : 563
      } ]
    }, {
      "id" : 128900,
      "points" : [ {
        "x" : 1685,
        "y" : 582
      } ]
    }, {
      "id" : 128895,
      "points" : [ {
        "x" : 1712,
        "y" : 519
      } ]
    }, {
      "id" : 128901,
      "points" : [ {
        "x" : 1684,
        "y" : 551
      } ]
    } ],
    "outputs" : [ {
      "id" : 128808,
      "points" : [ {
        "x" : 1711,
        "y" : 683
      } ]
    }, {
      "id" : 128902,
      "points" : [ {
        "x" : 1604,
        "y" : 655
      } ]
    }, {
      "id" : 128903,
      "points" : [ {
        "x" : 1658,
        "y" : 708
      } ]
    }, {
      "id" : 128904,
      "points" : [ {
        "x" : 1598,
        "y" : 615
      } ],
      "stoichiometry" : 2
    } ],
    "catalysts" : [ {
      "id" : 128905,
      "points" : [ {
        "x" : 1739,
        "y" : 605
      } ]
    } ]
  }, {
    "id" : 128837,
    "reactomeId" : 10735681,
    "displayName" : "AIR + CO2 => CAIR",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 1164,
      "y" : 233
    },
    "minX" : 1138,
    "maxX" : 1188,
    "minY" : 227,
    "maxY" : 239,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 1138,
        "y" : 233
      },
      "to" : {
        "x" : 1164,
        "y" : 233
      }
    }, {
      "from" : {
        "x" : 1164,
        "y" : 233
      },
      "to" : {
        "x" : 1188,
        "y" : 234
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 1158,
        "y" : 227
      },
      "b" : {
        "x" : 1170,
        "y" : 239
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 1164,
        "y" : 233
      }
    },
    "inputs" : [ {
      "id" : 128834,
      "points" : [ {
        "x" : 1114,
        "y" : 232
      } ]
    }, {
      "id" : 128838,
      "points" : [ {
        "x" : 1128,
        "y" : 265
      } ]
    } ],
    "outputs" : [ {
      "id" : 128839,
      "points" : [ {
        "x" : 1216,
        "y" : 232
      } ]
    }, {
      "id" : 128840,
      "points" : [ {
        "x" : 1188,
        "y" : 265
      } ]
    } ],
    "catalysts" : [ {
      "id" : 128841,
      "points" : [ {
        "x" : 1187,
        "y" : 184
      }, {
        "x" : 1164,
        "y" : 185
      } ]
    } ]
  }, {
    "id" : 128871,
    "reactomeId" : 10735218,
    "displayName" : "DHODH:FMN oxidises (S)-DHO to orotate",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 863,
      "y" : 619
    },
    "minX" : 802,
    "maxX" : 913,
    "minY" : 613,
    "maxY" : 625,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 802,
        "y" : 619
      },
      "to" : {
        "x" : 863,
        "y" : 619
      }
    }, {
      "from" : {
        "x" : 863,
        "y" : 619
      },
      "to" : {
        "x" : 913,
        "y" : 619
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 857,
        "y" : 613
      },
      "b" : {
        "x" : 869,
        "y" : 625
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 863,
        "y" : 619
      }
    },
    "inputs" : [ {
      "id" : 128872,
      "points" : [ {
        "x" : 736,
        "y" : 580
      } ]
    }, {
      "id" : 128870,
      "points" : [ {
        "x" : 765,
        "y" : 630
      } ]
    } ],
    "outputs" : [ {
      "id" : 128873,
      "points" : [ {
        "x" : 954,
        "y" : 633
      } ]
    }, {
      "id" : 128874,
      "points" : [ {
        "x" : 970,
        "y" : 580
      } ]
    } ],
    "catalysts" : [ {
      "id" : 128875,
      "points" : [ {
        "x" : 814,
        "y" : 579
      } ]
    } ]
  }, {
    "id" : 128809,
    "reactomeId" : 420911,
    "displayName" : "Formation of PPAT dimers",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 135,
      "y" : 101
    },
    "minX" : 129,
    "maxX" : 154,
    "minY" : 62,
    "maxY" : 169,
    "segments" : [ {
      "from" : {
        "x" : 154,
        "y" : 62
      },
      "to" : {
        "x" : 135,
        "y" : 101
      }
    }, {
      "from" : {
        "x" : 135,
        "y" : 101
      },
      "to" : {
        "x" : 153,
        "y" : 169
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 147,
        "y" : 163
      },
      "b" : {
        "x" : 153,
        "y" : 169
      },
      "c" : {
        "x" : 155,
        "y" : 161
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 155,
        "y" : 161
      }
    },
    "reactionShape" : {
      "a" : {
        "x" : 129,
        "y" : 95
      },
      "b" : {
        "x" : 141,
        "y" : 107
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 135,
        "y" : 101
      }
    },
    "inputs" : [ {
      "id" : 128805
    } ],
    "outputs" : [ {
      "id" : 128804,
      "stoichiometry" : 2
    } ],
    "activators" : [ {
      "id" : 128810,
      "points" : [ {
        "x" : 59,
        "y" : 214
      }, {
        "x" : 60,
        "y" : 100
      } ]
    } ]
  }, {
    "id" : 128811,
    "reactomeId" : 10735703,
    "displayName" : "5-phospho-alpha-D-ribose 1-diphosphate (PRPP) + H2O + L-glutamine <=> 5-phosphoribosylamine + L-glutamate +pyrophosphate",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 156,
      "y" : 232
    },
    "minX" : 118,
    "maxX" : 190,
    "minY" : 226,
    "maxY" : 238,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 118,
        "y" : 232
      },
      "to" : {
        "x" : 156,
        "y" : 232
      }
    }, {
      "from" : {
        "x" : 156,
        "y" : 232
      },
      "to" : {
        "x" : 190,
        "y" : 232
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 150,
        "y" : 226
      },
      "b" : {
        "x" : 162,
        "y" : 238
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 156,
        "y" : 232
      }
    },
    "inputs" : [ {
      "id" : 128812,
      "points" : [ {
        "x" : 78,
        "y" : 254
      } ]
    }, {
      "id" : 128813,
      "points" : [ {
        "x" : 96,
        "y" : 293
      } ]
    }, {
      "id" : 128810,
      "points" : [ {
        "x" : 86,
        "y" : 232
      } ]
    } ],
    "outputs" : [ {
      "id" : 128814,
      "points" : [ {
        "x" : 220,
        "y" : 232
      } ]
    }, {
      "id" : 128815,
      "points" : [ {
        "x" : 243,
        "y" : 316
      } ]
    }, {
      "id" : 128816,
      "points" : [ {
        "x" : 177,
        "y" : 292
      } ]
    } ],
    "catalysts" : [ {
      "id" : 128804,
      "points" : [ {
        "x" : 156,
        "y" : 197
      } ]
    } ]
  }, {
    "id" : 128906,
    "reactomeId" : 10738529,
    "displayName" : "IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS]",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 1942,
      "y" : 404
    },
    "minX" : 1936,
    "maxX" : 1948,
    "minY" : 337,
    "maxY" : 441,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 1939,
        "y" : 337
      },
      "to" : {
        "x" : 1942,
        "y" : 404
      }
    }, {
      "from" : {
        "x" : 1942,
        "y" : 404
      },
      "to" : {
        "x" : 1943,
        "y" : 441
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 1936,
        "y" : 398
      },
      "b" : {
        "x" : 1948,
        "y" : 410
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 1942,
        "y" : 404
      }
    },
    "inputs" : [ {
      "id" : 128806,
      "points" : [ {
        "x" : 1905,
        "y" : 256
      } ]
    }, {
      "id" : 128907,
      "points" : [ {
        "x" : 1957,
        "y" : 301
      } ]
    }, {
      "id" : 128908,
      "points" : [ {
        "x" : 1906,
        "y" : 328
      } ]
    } ],
    "outputs" : [ {
      "id" : 128909,
      "points" : [ {
        "x" : 1971,
        "y" : 456
      } ]
    }, {
      "id" : 128910,
      "points" : [ {
        "x" : 1944,
        "y" : 491
      } ]
    }, {
      "id" : 128911,
      "points" : [ {
        "x" : 1907,
        "y" : 485
      } ]
    }, {
      "id" : 128912,
      "points" : [ {
        "x" : 1895,
        "y" : 456
      } ],
      "stoichiometry" : 2
    } ],
    "catalysts" : [ {
      "id" : 128913,
      "points" : [ {
        "x" : 1899,
        "y" : 393
      } ]
    } ],
    "inhibitors" : [ {
      "id" : 128910,
      "points" : [ {
        "x" : 1972,
        "y" : 508
      }, {
        "x" : 2040,
        "y" : 508
      }, {
        "x" : 2039,
        "y" : 426
      } ]
    }, {
      "id" : 128914,
      "points" : [ {
        "x" : 1990,
        "y" : 381
      } ]
    }, {
      "id" : 128909,
      "points" : [ {
        "x" : 1985,
        "y" : 451
      } ]
    }, {
      "id" : 128808,
      "points" : [ {
        "x" : 1739,
        "y" : 690
      }, {
        "x" : 1810,
        "y" : 660
      }, {
        "x" : 1823,
        "y" : 449
      } ]
    } ]
  }, {
    "id" : 128842,
    "reactomeId" : 10735678,
    "displayName" : "CAIR + Aspartate + ATP => SAICAR + ADP + Pi",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 1330,
      "y" : 232
    },
    "minX" : 1295,
    "maxX" : 1355,
    "minY" : 226,
    "maxY" : 238,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 1295,
        "y" : 232
      },
      "to" : {
        "x" : 1330,
        "y" : 232
      }
    }, {
      "from" : {
        "x" : 1330,
        "y" : 232
      },
      "to" : {
        "x" : 1355,
        "y" : 232
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 1324,
        "y" : 226
      },
      "b" : {
        "x" : 1336,
        "y" : 238
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 1330,
        "y" : 232
      }
    },
    "inputs" : [ {
      "id" : 128843,
      "points" : [ {
        "x" : 1307,
        "y" : 265
      } ]
    }, {
      "id" : 128844,
      "points" : [ {
        "x" : 1262,
        "y" : 265
      } ]
    }, {
      "id" : 128839,
      "points" : [ {
        "x" : 1270,
        "y" : 232
      } ]
    } ],
    "outputs" : [ {
      "id" : 128845,
      "points" : [ {
        "x" : 1395,
        "y" : 232
      } ]
    }, {
      "id" : 128846,
      "points" : [ {
        "x" : 1370,
        "y" : 266
      } ]
    }, {
      "id" : 128847,
      "points" : [ {
        "x" : 1375,
        "y" : 204
      } ],
      "stoichiometry" : 2
    }, {
      "id" : 128848,
      "points" : [ {
        "x" : 1413,
        "y" : 272
      } ]
    } ],
    "catalysts" : [ {
      "id" : 128841,
      "points" : [ {
        "x" : 1312,
        "y" : 184
      }, {
        "x" : 1330,
        "y" : 185
      } ]
    } ]
  }, {
    "id" : 128876,
    "reactomeId" : 10735209,
    "displayName" : "UMPS dimer transfers phosphoribosyl group to ORO to form OMP",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 1113,
      "y" : 643
    },
    "minX" : 1086,
    "maxX" : 1164,
    "minY" : 637,
    "maxY" : 649,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 1086,
        "y" : 643
      },
      "to" : {
        "x" : 1113,
        "y" : 643
      }
    }, {
      "from" : {
        "x" : 1113,
        "y" : 643
      },
      "to" : {
        "x" : 1164,
        "y" : 642
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 1107,
        "y" : 637
      },
      "b" : {
        "x" : 1119,
        "y" : 649
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 1113,
        "y" : 643
      }
    },
    "inputs" : [ {
      "id" : 128873,
      "points" : [ {
        "x" : 1016,
        "y" : 643
      } ]
    }, {
      "id" : 128877,
      "points" : [ {
        "x" : 1070,
        "y" : 625
      } ]
    } ],
    "outputs" : [ {
      "id" : 128878,
      "points" : [ {
        "x" : 1218,
        "y" : 642
      } ]
    }, {
      "id" : 128879,
      "points" : [ {
        "x" : 1188,
        "y" : 544
      } ]
    } ],
    "catalysts" : [ {
      "id" : 128880,
      "points" : [ {
        "x" : 1193,
        "y" : 706
      }, {
        "x" : 1113,
        "y" : 687
      } ]
    } ]
  }, {
    "id" : 128881,
    "reactomeId" : 419461,
    "displayName" : "orotidine 5'-monophosphate => uridine 5'-monophosphate + CO2",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 1349,
      "y" : 643
    },
    "minX" : 1280,
    "maxX" : 1381,
    "minY" : 637,
    "maxY" : 649,
    "segments" : [ {
      "from" : {
        "x" : 1280,
        "y" : 643
      },
      "to" : {
        "x" : 1349,
        "y" : 643
      }
    }, {
      "from" : {
        "x" : 1349,
        "y" : 643
      },
      "to" : {
        "x" : 1381,
        "y" : 643
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 1343,
        "y" : 637
      },
      "b" : {
        "x" : 1355,
        "y" : 649
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 1349,
        "y" : 643
      }
    },
    "inputs" : [ {
      "id" : 128878
    } ],
    "outputs" : [ {
      "id" : 128882,
      "points" : [ {
        "x" : 1416,
        "y" : 643
      } ]
    }, {
      "id" : 128883,
      "points" : [ {
        "x" : 1397,
        "y" : 670
      } ]
    } ],
    "catalysts" : [ {
      "id" : 128880,
      "points" : [ {
        "x" : 1274,
        "y" : 706
      }, {
        "x" : 1349,
        "y" : 689
      } ]
    } ]
  }, {
    "id" : 128817,
    "reactomeId" : 10735694,
    "displayName" : "5-Phosphoribosylamine + Glycine + ATP => GAR + ADP + Pi",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 336,
      "y" : 231
    },
    "minX" : 302,
    "maxX" : 386,
    "minY" : 225,
    "maxY" : 237,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 302,
        "y" : 232
      },
      "to" : {
        "x" : 336,
        "y" : 231
      }
    }, {
      "from" : {
        "x" : 336,
        "y" : 231
      },
      "to" : {
        "x" : 386,
        "y" : 231
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 330,
        "y" : 225
      },
      "b" : {
        "x" : 342,
        "y" : 237
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 336,
        "y" : 231
      }
    },
    "inputs" : [ {
      "id" : 128818,
      "points" : [ {
        "x" : 308,
        "y" : 274
      } ]
    }, {
      "id" : 128814,
      "points" : [ {
        "x" : 266,
        "y" : 232
      } ]
    }, {
      "id" : 128819,
      "points" : [ {
        "x" : 276,
        "y" : 259
      } ]
    } ],
    "outputs" : [ {
      "id" : 128820,
      "points" : [ {
        "x" : 421,
        "y" : 231
      } ]
    }, {
      "id" : 128821,
      "points" : [ {
        "x" : 408,
        "y" : 251
      } ]
    }, {
      "id" : 128822,
      "points" : [ {
        "x" : 373,
        "y" : 272
      } ]
    }, {
      "id" : 128823,
      "points" : [ {
        "x" : 411,
        "y" : 300
      } ]
    } ],
    "catalysts" : [ {
      "id" : 128824,
      "points" : [ {
        "x" : 426,
        "y" : 152
      }, {
        "x" : 337,
        "y" : 183
      } ]
    } ]
  }, {
    "id" : 128849,
    "reactomeId" : 10735669,
    "displayName" : "SAICAR => AICAR + Fumarate",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 1497,
      "y" : 232
    },
    "minX" : 1465,
    "maxX" : 1525,
    "minY" : 226,
    "maxY" : 238,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 1465,
        "y" : 232
      },
      "to" : {
        "x" : 1497,
        "y" : 232
      }
    }, {
      "from" : {
        "x" : 1497,
        "y" : 232
      },
      "to" : {
        "x" : 1525,
        "y" : 231
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 1491,
        "y" : 226
      },
      "b" : {
        "x" : 1503,
        "y" : 238
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 1497,
        "y" : 232
      }
    },
    "inputs" : [ {
      "id" : 128845
    } ],
    "outputs" : [ {
      "id" : 128850,
      "points" : [ {
        "x" : 1557,
        "y" : 231
      } ]
    }, {
      "id" : 128851,
      "points" : [ {
        "x" : 1528,
        "y" : 265
      } ]
    } ],
    "catalysts" : [ {
      "id" : 128852,
      "points" : [ {
        "x" : 1494,
        "y" : 192
      } ]
    } ]
  }, {
    "id" : 128915,
    "reactomeId" : 10735705,
    "displayName" : "adenylosuccinate => adenosine 5'-monophosphate + fumarate",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 1946,
      "y" : 575
    },
    "minX" : 1940,
    "maxX" : 1952,
    "minY" : 527,
    "maxY" : 616,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 1945,
        "y" : 527
      },
      "to" : {
        "x" : 1946,
        "y" : 575
      }
    }, {
      "from" : {
        "x" : 1946,
        "y" : 575
      },
      "to" : {
        "x" : 1946,
        "y" : 616
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 1940,
        "y" : 569
      },
      "b" : {
        "x" : 1952,
        "y" : 581
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 1946,
        "y" : 575
      }
    },
    "inputs" : [ {
      "id" : 128910
    } ],
    "outputs" : [ {
      "id" : 128916,
      "points" : [ {
        "x" : 1991,
        "y" : 622
      } ]
    }, {
      "id" : 128807,
      "points" : [ {
        "x" : 1947,
        "y" : 655
      } ]
    } ],
    "catalysts" : [ {
      "id" : 128917,
      "points" : [ {
        "x" : 1980,
        "y" : 574
      } ]
    } ]
  }, {
    "id" : 128853,
    "reactomeId" : 419440,
    "displayName" : "L-glutamine + 2 ATP + HCO3- + H2O => carbamoyl phosphate + L-glutamate + 2 ADP + orthophosphate",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 156,
      "y" : 642
    },
    "minX" : 118,
    "maxX" : 184,
    "minY" : 636,
    "maxY" : 648,
    "segments" : [ {
      "from" : {
        "x" : 118,
        "y" : 641
      },
      "to" : {
        "x" : 156,
        "y" : 642
      }
    }, {
      "from" : {
        "x" : 156,
        "y" : 642
      },
      "to" : {
        "x" : 184,
        "y" : 642
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 150,
        "y" : 636
      },
      "b" : {
        "x" : 162,
        "y" : 648
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 156,
        "y" : 642
      }
    },
    "inputs" : [ {
      "id" : 128854,
      "points" : [ {
        "x" : 82,
        "y" : 650
      } ]
    }, {
      "id" : 128855,
      "points" : [ {
        "x" : 90,
        "y" : 676
      } ],
      "stoichiometry" : 2
    }, {
      "id" : 128856,
      "points" : [ {
        "x" : 85,
        "y" : 628
      } ]
    }, {
      "id" : 128857,
      "points" : [ {
        "x" : 96,
        "y" : 586
      } ]
    } ],
    "outputs" : [ {
      "id" : 128858,
      "points" : [ {
        "x" : 235,
        "y" : 642
      } ]
    }, {
      "id" : 128859,
      "points" : [ {
        "x" : 224,
        "y" : 702
      } ],
      "stoichiometry" : 2
    }, {
      "id" : 128860,
      "points" : [ {
        "x" : 189,
        "y" : 726
      } ]
    }, {
      "id" : 128861,
      "points" : [ {
        "x" : 156,
        "y" : 691
      } ]
    } ],
    "catalysts" : [ {
      "id" : 128862,
      "points" : [ {
        "x" : 294,
        "y" : 588
      }, {
        "x" : 157,
        "y" : 591
      } ]
    } ]
  }, {
    "id" : 128884,
    "reactomeId" : 10735661,
    "displayName" : "AICAR + 10-Formyl-THF => FAICAR + THF",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 1664,
      "y" : 231
    },
    "minX" : 1643,
    "maxX" : 1689,
    "minY" : 225,
    "maxY" : 237,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 1643,
        "y" : 230
      },
      "to" : {
        "x" : 1664,
        "y" : 231
      }
    }, {
      "from" : {
        "x" : 1664,
        "y" : 231
      },
      "to" : {
        "x" : 1689,
        "y" : 233
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 1658,
        "y" : 225
      },
      "b" : {
        "x" : 1670,
        "y" : 237
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 1664,
        "y" : 231
      }
    },
    "inputs" : [ {
      "id" : 128850,
      "points" : [ {
        "x" : 1619,
        "y" : 230
      } ]
    }, {
      "id" : 128885,
      "points" : [ {
        "x" : 1632,
        "y" : 262
      } ]
    } ],
    "outputs" : [ {
      "id" : 128886,
      "points" : [ {
        "x" : 1709,
        "y" : 233
      } ]
    }, {
      "id" : 128887,
      "points" : [ {
        "x" : 1712,
        "y" : 265
      } ]
    } ],
    "catalysts" : [ {
      "id" : 128888,
      "points" : [ {
        "x" : 1682,
        "y" : 182
      }, {
        "x" : 1664,
        "y" : 182
      } ]
    } ]
  }, {
    "id" : 128918,
    "reactomeId" : 10817555,
    "displayName" : "IMPDH tetramers bind IMPDH inhibitors",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 1409,
      "y" : 421
    },
    "minX" : 1403,
    "maxX" : 1464,
    "minY" : 415,
    "maxY" : 436,
    "reactionType" : "binding",
    "segments" : [ {
      "from" : {
        "x" : 1409,
        "y" : 420
      },
      "to" : {
        "x" : 1409,
        "y" : 421
      }
    }, {
      "from" : {
        "x" : 1409,
        "y" : 421
      },
      "to" : {
        "x" : 1464,
        "y" : 436
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 1456,
        "y" : 438
      },
      "b" : {
        "x" : 1464,
        "y" : 436
      },
      "c" : {
        "x" : 1458,
        "y" : 430
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 1458,
        "y" : 430
      }
    },
    "reactionShape" : {
      "c" : {
        "x" : 1409,
        "y" : 421
      },
      "r" : 5,
      "type" : "CIRCLE",
      "centre" : {
        "x" : 1409,
        "y" : 421
      }
    },
    "inputs" : [ {
      "id" : 128919,
      "points" : [ {
        "x" : 1381,
        "y" : 377
      } ]
    }, {
      "id" : 128897,
      "points" : [ {
        "x" : 1479,
        "y" : 395
      } ]
    } ],
    "outputs" : [ {
      "id" : 128920
    } ]
  }, {
    "id" : 128825,
    "reactomeId" : 10735691,
    "displayName" : "GAR + 10-Formyl-THF => FGAR + THF",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 551,
      "y" : 232
    },
    "minX" : 514,
    "maxX" : 579,
    "minY" : 226,
    "maxY" : 238,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 514,
        "y" : 231
      },
      "to" : {
        "x" : 551,
        "y" : 232
      }
    }, {
      "from" : {
        "x" : 551,
        "y" : 232
      },
      "to" : {
        "x" : 579,
        "y" : 233
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 545,
        "y" : 226
      },
      "b" : {
        "x" : 557,
        "y" : 238
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 551,
        "y" : 232
      }
    },
    "inputs" : [ {
      "id" : 128826,
      "points" : [ {
        "x" : 511,
        "y" : 269
      } ]
    }, {
      "id" : 128820,
      "points" : [ {
        "x" : 475,
        "y" : 231
      } ]
    } ],
    "outputs" : [ {
      "id" : 128827,
      "points" : [ {
        "x" : 597,
        "y" : 295
      } ]
    }, {
      "id" : 128828,
      "points" : [ {
        "x" : 604,
        "y" : 232
      } ]
    }, {
      "id" : 128829,
      "points" : [ {
        "x" : 611,
        "y" : 258
      } ]
    } ],
    "catalysts" : [ {
      "id" : 128824,
      "points" : [ {
        "x" : 477,
        "y" : 154
      }, {
        "x" : 551,
        "y" : 185
      } ]
    } ]
  }, {
    "id" : 128889,
    "reactomeId" : 10735658,
    "displayName" : "FAICAR => IMP + H2O",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 1804,
      "y" : 233
    },
    "minX" : 1779,
    "maxX" : 1836,
    "minY" : 227,
    "maxY" : 239,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 1779,
        "y" : 233
      },
      "to" : {
        "x" : 1804,
        "y" : 233
      }
    }, {
      "from" : {
        "x" : 1804,
        "y" : 233
      },
      "to" : {
        "x" : 1836,
        "y" : 234
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 1798,
        "y" : 227
      },
      "b" : {
        "x" : 1810,
        "y" : 239
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 1804,
        "y" : 233
      }
    },
    "inputs" : [ {
      "id" : 128886
    } ],
    "outputs" : [ {
      "id" : 128890,
      "points" : [ {
        "x" : 1804,
        "y" : 257
      } ]
    }, {
      "id" : 128806,
      "points" : [ {
        "x" : 1872,
        "y" : 236
      } ]
    } ],
    "catalysts" : [ {
      "id" : 128888,
      "points" : [ {
        "x" : 1784,
        "y" : 184
      }, {
        "x" : 1802,
        "y" : 185
      } ]
    } ]
  }, {
    "id" : 128921,
    "reactomeId" : 10818352,
    "displayName" : "DHODH:FMN binds DHODH inhibitors",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 811,
      "y" : 518
    },
    "minX" : 805,
    "maxX" : 858,
    "minY" : 512,
    "maxY" : 538,
    "reactionType" : "binding",
    "segments" : [ {
      "from" : {
        "x" : 812,
        "y" : 518
      },
      "to" : {
        "x" : 811,
        "y" : 518
      }
    }, {
      "from" : {
        "x" : 811,
        "y" : 518
      },
      "to" : {
        "x" : 858,
        "y" : 538
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 850,
        "y" : 539
      },
      "b" : {
        "x" : 858,
        "y" : 538
      },
      "c" : {
        "x" : 853,
        "y" : 532
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 853,
        "y" : 532
      }
    },
    "reactionShape" : {
      "c" : {
        "x" : 811,
        "y" : 518
      },
      "r" : 5,
      "type" : "CIRCLE",
      "centre" : {
        "x" : 811,
        "y" : 518
      }
    },
    "inputs" : [ {
      "id" : 128922,
      "points" : [ {
        "x" : 644,
        "y" : 518
      } ]
    }, {
      "id" : 128875,
      "points" : [ {
        "x" : 802,
        "y" : 540
      } ]
    } ],
    "outputs" : [ {
      "id" : 128923
    } ]
  }, {
    "id" : 128891,
    "reactomeId" : 421222,
    "displayName" : "inosine 5'-monophosphate (IMP) + NAD+ + H2O => xanthosine 5'-monophosphate (XMP) + NADH + H+",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 1711,
      "y" : 415
    },
    "minX" : 1705,
    "maxX" : 1717,
    "minY" : 368,
    "maxY" : 446,
    "segments" : [ {
      "from" : {
        "x" : 1711,
        "y" : 368
      },
      "to" : {
        "x" : 1711,
        "y" : 415
      }
    }, {
      "from" : {
        "x" : 1711,
        "y" : 415
      },
      "to" : {
        "x" : 1711,
        "y" : 446
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 1705,
        "y" : 409
      },
      "b" : {
        "x" : 1717,
        "y" : 421
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 1711,
        "y" : 415
      }
    },
    "inputs" : [ {
      "id" : 128892,
      "points" : [ {
        "x" : 1691,
        "y" : 355
      } ]
    }, {
      "id" : 128806,
      "points" : [ {
        "x" : 1877,
        "y" : 256
      } ]
    }, {
      "id" : 128893,
      "points" : [ {
        "x" : 1679,
        "y" : 372
      } ]
    } ],
    "outputs" : [ {
      "id" : 128894,
      "points" : [ {
        "x" : 1651,
        "y" : 453
      } ]
    }, {
      "id" : 128895,
      "points" : [ {
        "x" : 1711,
        "y" : 483
      } ]
    }, {
      "id" : 128896,
      "points" : [ {
        "x" : 1673,
        "y" : 472
      } ]
    } ],
    "catalysts" : [ {
      "id" : 128897,
      "points" : [ {
        "x" : 1579,
        "y" : 389
      } ]
    } ],
    "inhibitors" : [ {
      "id" : 128895,
      "points" : [ {
        "x" : 1720,
        "y" : 483
      }, {
        "x" : 1761,
        "y" : 415
      } ]
    } ]
  }, {
    "id" : 128863,
    "reactomeId" : 419451,
    "displayName" : "carbamoyl phosphate + L-aspartate <=> N-carbamoyl L-aspartate + orthophosphate",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 350,
      "y" : 643
    },
    "minX" : 326,
    "maxX" : 386,
    "minY" : 637,
    "maxY" : 649,
    "segments" : [ {
      "from" : {
        "x" : 326,
        "y" : 643
      },
      "to" : {
        "x" : 350,
        "y" : 643
      }
    }, {
      "from" : {
        "x" : 350,
        "y" : 643
      },
      "to" : {
        "x" : 386,
        "y" : 645
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 344,
        "y" : 637
      },
      "b" : {
        "x" : 356,
        "y" : 649
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 350,
        "y" : 643
      }
    },
    "inputs" : [ {
      "id" : 128858,
      "points" : [ {
        "x" : 281,
        "y" : 643
      } ]
    }, {
      "id" : 128864,
      "points" : [ {
        "x" : 317,
        "y" : 686
      } ]
    } ],
    "outputs" : [ {
      "id" : 128865,
      "points" : [ {
        "x" : 423,
        "y" : 644
      } ]
    }, {
      "id" : 128866,
      "points" : [ {
        "x" : 393,
        "y" : 680
      } ]
    } ],
    "catalysts" : [ {
      "id" : 128862,
      "points" : [ {
        "x" : 351,
        "y" : 601
      } ]
    } ]
  }, {
    "id" : 128830,
    "reactomeId" : 10735688,
    "displayName" : "FGAM + ATP => AIR + ADP + Pi",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 998,
      "y" : 232
    },
    "minX" : 957,
    "maxX" : 1035,
    "minY" : 226,
    "maxY" : 238,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 957,
        "y" : 232
      },
      "to" : {
        "x" : 998,
        "y" : 232
      }
    }, {
      "from" : {
        "x" : 998,
        "y" : 232
      },
      "to" : {
        "x" : 1035,
        "y" : 233
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 992,
        "y" : 226
      },
      "b" : {
        "x" : 1004,
        "y" : 238
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 998,
        "y" : 232
      }
    },
    "inputs" : [ {
      "id" : 128831,
      "points" : [ {
        "x" : 941,
        "y" : 208
      } ]
    }, {
      "id" : 128832,
      "points" : [ {
        "x" : 928,
        "y" : 232
      } ]
    } ],
    "outputs" : [ {
      "id" : 128833,
      "points" : [ {
        "x" : 1019,
        "y" : 265
      } ]
    }, {
      "id" : 128834,
      "points" : [ {
        "x" : 1068,
        "y" : 232
      } ]
    }, {
      "id" : 128835,
      "points" : [ {
        "x" : 1056,
        "y" : 265
      } ]
    }, {
      "id" : 128836,
      "points" : [ {
        "x" : 1057,
        "y" : 208
      } ]
    } ],
    "catalysts" : [ {
      "id" : 128824,
      "points" : [ {
        "x" : 477,
        "y" : 145
      }, {
        "x" : 998,
        "y" : 165
      } ]
    } ]
  } ],
  "compartments" : [ {
    "id" : 128931,
    "reactomeId" : 17927,
    "displayName" : "mitochondrial intermembrane space",
    "schemaClass" : "Compartment",
    "renderableClass" : "Compartment",
    "position" : {
      "x" : 849,
      "y" : 514
    },
    "minX" : 668,
    "maxX" : 1031,
    "minY" : 430,
    "maxY" : 598,
    "prop" : {
      "x" : 668,
      "y" : 430,
      "width" : 363,
      "height" : 168
    },
    "textPosition" : {
      "x" : 695,
      "y" : 444
    },
    "insets" : {
      "x" : 678,
      "y" : 440,
      "width" : 343,
      "height" : 148
    },
    "bgColor" : {
      "r" : 250,
      "g" : 240,
      "b" : 240
    },
    "componentIds" : [ 128930 ]
  }, {
    "id" : 128930,
    "reactomeId" : 5460,
    "displayName" : "mitochondrial matrix",
    "schemaClass" : "Compartment",
    "renderableClass" : "Compartment",
    "position" : {
      "x" : 855,
      "y" : 524
    },
    "minX" : 710,
    "maxX" : 1001,
    "minY" : 480,
    "maxY" : 568,
    "prop" : {
      "x" : 710,
      "y" : 480,
      "width" : 291,
      "height" : 88
    },
    "textPosition" : {
      "x" : 722,
      "y" : 491
    },
    "insets" : {
      "x" : 720,
      "y" : 490,
      "width" : 271,
      "height" : 68
    },
    "bgColor" : {
      "r" : 250,
      "g" : 240,
      "b" : 240
    },
    "componentIds" : [ 128875, 128872, 128874, 128921, 128923 ]
  }, {
    "id" : 128924,
    "reactomeId" : 70101,
    "displayName" : "cytosol",
    "schemaClass" : "Compartment",
    "renderableClass" : "Compartment",
    "position" : {
      "x" : 1069,
      "y" : 393
    },
    "minX" : 0,
    "maxX" : 2138,
    "minY" : 0,
    "maxY" : 787,
    "prop" : {
      "x" : 0,
      "y" : 0,
      "width" : 2138,
      "height" : 787
    },
    "textPosition" : {
      "x" : 31,
      "y" : 726
    },
    "insets" : {
      "x" : 10,
      "y" : 10,
      "width" : 2118,
      "height" : 767
    },
    "bgColor" : {
      "r" : 250,
      "g" : 240,
      "b" : 240
    },
    "componentIds" : [ 128803, 128804, 128805, 128809, 128810, 128811, 128812, 128813, 128816, 128814, 128817, 128818, 128819, 128820, 128823, 128824, 128821, 128825, 128826, 128828, 128827, 128902, 128806, 128832, 128830, 128834, 128835, 128837, 128838, 128839, 128841, 128842, 128843, 128844, 128845, 128848, 128849, 128850, 128851, 128852, 128853, 128854, 128855, 128856, 128858, 128862, 128857, 128860, 128861, 128863, 128865, 128866, 128864, 128867, 128868, 128869, 128871, 128870, 128873, 128878, 128880, 128876, 128877, 128882, 128881, 128883, 128884, 128886, 128888, 128885, 128887, 128889, 128890, 128891, 128895, 128897, 128892, 128893, 128894, 128896, 128898, 128899, 128900, 128905, 128808, 128901, 128903, 128906, 128907, 128909, 128913, 128914, 128910, 128911, 128915, 128917, 128916, 128807, 128908, 128918, 128919, 128920, 128931, 128831, 128922, 128822, 128829, 128833, 128836, 128934, 128859, 128840, 128847, 128912, 128815, 128879, 128904, 128939, 128940, 128941, 128846 ]
  } ],
  "notes" : [ ],
  "links" : [ {
    "id" : 128939,
    "renderableClass" : "Interaction",
    "position" : {
      "x" : 1133,
      "y" : 368
    },
    "minX" : 890,
    "maxX" : 1558,
    "minY" : 362,
    "maxY" : 600,
    "interactionType" : "Activate",
    "segments" : [ {
      "from" : {
        "x" : 1558,
        "y" : 600
      },
      "to" : {
        "x" : 1133,
        "y" : 368
      }
    }, {
      "from" : {
        "x" : 1133,
        "y" : 368
      },
      "to" : {
        "x" : 890,
        "y" : 368
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 897,
        "y" : 364
      },
      "b" : {
        "x" : 890,
        "y" : 368
      },
      "c" : {
        "x" : 897,
        "y" : 372
      },
      "type" : "ARROW",
      "empty" : true,
      "centre" : {
        "x" : 897,
        "y" : 372
      }
    },
    "reactionShape" : {
      "a" : {
        "x" : 1127,
        "y" : 362
      },
      "b" : {
        "x" : 1139,
        "y" : 374
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 1133,
        "y" : 368
      }
    },
    "inputs" : [ {
      "id" : 128904
    } ],
    "outputs" : [ {
      "id" : 128934
    } ]
  }, {
    "id" : 128941,
    "renderableClass" : "Interaction",
    "position" : {
      "x" : 368,
      "y" : 367
    },
    "minX" : 273,
    "maxX" : 760,
    "minY" : 338,
    "maxY" : 373,
    "interactionType" : "Activate",
    "segments" : [ {
      "from" : {
        "x" : 273,
        "y" : 338
      },
      "to" : {
        "x" : 368,
        "y" : 367
      }
    }, {
      "from" : {
        "x" : 368,
        "y" : 367
      },
      "to" : {
        "x" : 760,
        "y" : 367
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 753,
        "y" : 371
      },
      "b" : {
        "x" : 760,
        "y" : 367
      },
      "c" : {
        "x" : 753,
        "y" : 363
      },
      "type" : "ARROW",
      "empty" : true,
      "centre" : {
        "x" : 753,
        "y" : 363
      }
    },
    "reactionShape" : {
      "a" : {
        "x" : 362,
        "y" : 361
      },
      "b" : {
        "x" : 374,
        "y" : 373
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 368,
        "y" : 367
      }
    },
    "inputs" : [ {
      "id" : 128815
    } ],
    "outputs" : [ {
      "id" : 128934
    } ]
  }, {
    "id" : 128940,
    "renderableClass" : "Interaction",
    "position" : {
      "x" : 1131,
      "y" : 415
    },
    "minX" : 890,
    "maxX" : 1183,
    "minY" : 377,
    "maxY" : 507,
    "interactionType" : "Activate",
    "segments" : [ {
      "from" : {
        "x" : 1183,
        "y" : 507
      },
      "to" : {
        "x" : 1131,
        "y" : 415
      }
    }, {
      "from" : {
        "x" : 1131,
        "y" : 415
      },
      "to" : {
        "x" : 890,
        "y" : 377
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 897,
        "y" : 374
      },
      "b" : {
        "x" : 890,
        "y" : 377
      },
      "c" : {
        "x" : 896,
        "y" : 382
      },
      "type" : "ARROW",
      "empty" : true,
      "centre" : {
        "x" : 896,
        "y" : 382
      }
    },
    "reactionShape" : {
      "a" : {
        "x" : 1125,
        "y" : 409
      },
      "b" : {
        "x" : 1137,
        "y" : 421
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 1131,
        "y" : 415
      }
    },
    "inputs" : [ {
      "id" : 128879
    } ],
    "outputs" : [ {
      "id" : 128934
    } ]
  } ],
  "shadows" : [ {
    "id" : 128943,
    "reactomeId" : 10825345,
    "displayName" : "Purine ribonucleoside monophosphate biosynthesis",
    "schemaClass" : "Pathway",
    "renderableClass" : "Shadow",
    "position" : {
      "x" : 1043,
      "y" : 376
    },
    "minX" : 17,
    "maxX" : 2070,
    "minY" : 27,
    "maxY" : 726,
    "prop" : {
      "x" : 17,
      "y" : 27,
      "width" : 2053,
      "height" : 463
    },
    "points" : [ {
      "x" : 17,
      "y" : 27
    }, {
      "x" : 2070,
      "y" : 27
    }, {
      "x" : 2070,
      "y" : 726
    }, {
      "x" : 17,
      "y" : 726
    } ],
    "colour" : "#dc3912"
  }, {
    "id" : 128942,
    "reactomeId" : 10825321,
    "displayName" : "Pyrimidine biosynthesis",
    "schemaClass" : "Pathway",
    "renderableClass" : "Shadow",
    "position" : {
      "x" : 917,
      "y" : 615
    },
    "minX" : 540,
    "maxX" : 1295,
    "minY" : 490,
    "maxY" : 741,
    "prop" : {
      "x" : 540,
      "y" : 490,
      "width" : 755,
      "height" : 251
    },
    "points" : [ {
      "x" : 540,
      "y" : 490
    }, {
      "x" : 1295,
      "y" : 490
    }, {
      "x" : 1295,
      "y" : 741
    }, {
      "x" : 540,
      "y" : 741
    } ],
    "colour" : "#4684ee"
  } ],
  "minX" : 0,
  "maxX" : 2138,
  "minY" : 0,
  "maxY" : 787,
  "disease" : false
}