{
  "dbId" : 10731086,
  "stId" : "R-XTR-8854214",
  "speciesName" : "Xenopus tropicalis",
  "nodes" : [ {
    "dbId" : 2213216,
    "stId" : "R-ALL-2213216",
    "displayName" : "GTP [lysosomal membrane]",
    "schemaClass" : "SimpleEntity",
    "speciesId" : 0,
    "identifier" : "15996",
    "standardIdentifier" : "chebi:15996",
    "referenceType" : "ReferenceMolecule",
    "parents" : [ 10713070 ],
    "children" : [ ]
  }, {
    "dbId" : 10713058,
    "stId" : "R-XTR-8854149",
    "displayName" : "tbc1d17 [recycling endosome]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 205621,
    "diagramIds" : [ 136478 ],
    "identifier" : "A0A6I8PR66",
    "standardIdentifier" : "uniprot:A0A6I8PR66",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "tbc1d17" ],
    "parents" : [ 10713060 ],
    "children" : [ ]
  }, {
    "dbId" : 10713060,
    "stId" : "R-XTR-8854298",
    "displayName" : "OPTN:RAB8:GTP:TBC1D17 [recycling endosome membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 205621,
    "diagramIds" : [ 136480 ],
    "parents" : [ ],
    "children" : [ 10713054, 10713058 ]
  }, {
    "dbId" : 10713070,
    "stId" : "R-XTR-2213222",
    "displayName" : "RAB7A:GTP [lysosomal membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 205621,
    "diagramIds" : [ 136458, 136473 ],
    "parents" : [ ],
    "children" : [ 10713068, 2213216 ]
  }, {
    "dbId" : 10713068,
    "stId" : "R-XTR-2213231",
    "displayName" : "rab7a [lysosomal membrane]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 205621,
    "identifier" : "Q66JI1",
    "standardIdentifier" : "uniprot:Q66JI1",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "rab7a" ],
    "parents" : [ 10713085, 10713072, 10713070 ],
    "children" : [ ]
  }, {
    "dbId" : 10713072,
    "stId" : "R-XTR-8854176",
    "displayName" : "RAB7A:GDP [lysosomal membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 205621,
    "diagramIds" : [ 136459 ],
    "parents" : [ ],
    "children" : [ 10713068, 29420 ]
  }, {
    "dbId" : 9628545,
    "stId" : "R-ALL-9628545",
    "displayName" : "GDP [lysosomal membrane]",
    "schemaClass" : "SimpleEntity",
    "speciesId" : 0,
    "identifier" : "17552",
    "standardIdentifier" : "chebi:17552",
    "referenceType" : "ReferenceMolecule",
    "parents" : [ 10713085 ],
    "children" : [ ]
  }, {
    "dbId" : 10713079,
    "stId" : "R-XTR-8854154",
    "displayName" : "tbc1d7 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 205621,
    "diagramIds" : [ 136462 ],
    "identifier" : "F6UMY3",
    "standardIdentifier" : "uniprot:F6UMY3",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "tbc1d7" ],
    "parents" : [ 10713081 ],
    "children" : [ ]
  }, {
    "dbId" : 10713081,
    "stId" : "R-XTR-8854324",
    "displayName" : "TBC1D7:TSC1:TSC2 [cytosol]",
    "schemaClass" : "Complex",
    "speciesId" : 205621,
    "diagramIds" : [ 136464 ],
    "parents" : [ ],
    "children" : [ 10660685, 10713079 ]
  }, {
    "dbId" : 10713085,
    "stId" : "R-XTR-8854216",
    "displayName" : "RAB7:GDP [lysosomal membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 205621,
    "diagramIds" : [ 136474 ],
    "parents" : [ ],
    "children" : [ 10713068, 9628545 ]
  }, {
    "dbId" : 10713089,
    "stId" : "R-XTR-8854150",
    "displayName" : "tbc1d15 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 205621,
    "diagramIds" : [ 136476 ],
    "identifier" : "Q6P4X9",
    "standardIdentifier" : "uniprot:Q6P4X9",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "tbc1d15" ],
    "parents" : [ ],
    "children" : [ ]
  }, {
    "dbId" : 10660672,
    "stId" : "R-XTR-2980548",
    "displayName" : "tsc2 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 205621,
    "identifier" : "A0A6I8SAH2",
    "standardIdentifier" : "uniprot:A0A6I8SAH2",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "tsc2" ],
    "parents" : [ 10660685 ],
    "children" : [ ]
  }, {
    "dbId" : 10713030,
    "stId" : "R-XTR-8854335",
    "displayName" : "RAB35:GTP [clathrin-coated endocytic vesicle membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 205621,
    "diagramIds" : [ 136467 ],
    "parents" : [ ],
    "children" : [ 29438, 10713028 ]
  }, {
    "dbId" : 10713028,
    "stId" : "R-XTR-8854153",
    "displayName" : "rab35 [clathrin-coated endocytic vesicle membrane]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 205621,
    "identifier" : "Q6P7Z7",
    "standardIdentifier" : "uniprot:Q6P7Z7",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "rab35" ],
    "parents" : [ 10713032, 10713030 ],
    "children" : [ ]
  }, {
    "dbId" : 10660683,
    "stId" : "R-XTR-5672338",
    "displayName" : "tsc1 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 205621,
    "identifier" : "A0A6I8RQS4",
    "standardIdentifier" : "uniprot:A0A6I8RQS4",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "tsc1" ],
    "parents" : [ 10660685 ],
    "children" : [ ]
  }, {
    "dbId" : 10713032,
    "stId" : "R-XTR-8854215",
    "displayName" : "RAB35:GDP [clathrin-coated endocytic vesicle membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 205621,
    "diagramIds" : [ 136468 ],
    "parents" : [ ],
    "children" : [ 29420, 10713028 ]
  }, {
    "dbId" : 29356,
    "stId" : "R-ALL-29356",
    "displayName" : "H2O [cytosol]",
    "schemaClass" : "SimpleEntity",
    "speciesId" : 0,
    "diagramIds" : [ 136466, 136482, 136472, 136457 ],
    "identifier" : "15377",
    "standardIdentifier" : "chebi:15377",
    "referenceType" : "ReferenceMolecule",
    "parents" : [ ],
    "children" : [ ]
  }, {
    "dbId" : 29420,
    "stId" : "R-ALL-29420",
    "displayName" : "GDP [cytosol]",
    "schemaClass" : "SimpleEntity",
    "speciesId" : 0,
    "identifier" : "58189",
    "standardIdentifier" : "chebi:58189",
    "referenceType" : "ReferenceMolecule",
    "parents" : [ 10713032, 10713108, 10713072 ],
    "children" : [ ]
  }, {
    "dbId" : 10713102,
    "stId" : "R-XTR-8854609",
    "displayName" : "rab33b [Golgi membrane]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 205621,
    "identifier" : "Q66IK6",
    "standardIdentifier" : "uniprot:Q66IK6",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "rab33b" ],
    "parents" : [ 10713104 ],
    "children" : [ ]
  }, {
    "dbId" : 10713037,
    "stId" : "R-XTR-8854148",
    "displayName" : "tbc1d13 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 205621,
    "diagramIds" : [ 136470 ],
    "identifier" : "B1H3K6",
    "standardIdentifier" : "uniprot:B1H3K6",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "tbc1d13" ],
    "parents" : [ ],
    "children" : [ ]
  }, {
    "dbId" : 10713100,
    "stId" : "R-XTR-8854592",
    "displayName" : "rab33a [Golgi membrane]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 205621,
    "identifier" : "F7AXL2",
    "standardIdentifier" : "uniprot:F7AXL2",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "rab33a" ],
    "parents" : [ 10713104 ],
    "children" : [ ]
  }, {
    "dbId" : 10660685,
    "stId" : "R-XTR-165175",
    "displayName" : "TSC1:TSC2 [cytosol]",
    "schemaClass" : "Complex",
    "speciesId" : 205621,
    "diagramIds" : [ 136463 ],
    "parents" : [ 10713081 ],
    "children" : [ 10660683, 10660672 ]
  }, {
    "dbId" : 10713106,
    "stId" : "R-XTR-8854602",
    "displayName" : "RAB33:GTP [Golgi membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 205621,
    "diagramIds" : [ 136483 ],
    "parents" : [ ],
    "children" : [ 29438, 10713104 ]
  }, {
    "dbId" : 10713042,
    "stId" : "R-XTR-8854141",
    "displayName" : "optn [recycling endosome membrane]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 205621,
    "identifier" : "F6Z6G3",
    "standardIdentifier" : "uniprot:F6Z6G3",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "optn" ],
    "parents" : [ 10713054 ],
    "children" : [ ]
  }, {
    "dbId" : 10713104,
    "stId" : "R-XTR-8854614",
    "displayName" : "RAB33 [Golgi membrane]",
    "schemaClass" : "CandidateSet",
    "speciesId" : 205621,
    "parents" : [ 10713108, 10713106 ],
    "children" : [ 10713100, 10713102 ]
  }, {
    "dbId" : 10713108,
    "stId" : "R-XTR-8854591",
    "displayName" : "RAB33:GDP [Golgi membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 205621,
    "diagramIds" : [ 136484 ],
    "parents" : [ ],
    "children" : [ 29420, 10713104 ]
  }, {
    "dbId" : 10713044,
    "stId" : "R-XTR-8854145",
    "displayName" : "rab8a [recycling endosome membrane]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 205621,
    "identifier" : "A0A803K2C5",
    "standardIdentifier" : "uniprot:A0A803K2C5",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "rab8a" ],
    "parents" : [ 10713050 ],
    "children" : [ ]
  }, {
    "dbId" : 10713050,
    "stId" : "R-XTR-8854297",
    "displayName" : "RAB8 [recycling endosome membrane]",
    "schemaClass" : "DefinedSet",
    "speciesId" : 205621,
    "parents" : [ 10713052 ],
    "children" : [ 10713048, 10713044 ]
  }, {
    "dbId" : 10713048,
    "stId" : "R-XTR-8854156",
    "displayName" : "rab8b [recycling endosome membrane]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 205621,
    "identifier" : "A0JPA5",
    "standardIdentifier" : "uniprot:A0JPA5",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "rab8b" ],
    "parents" : [ 10713050 ],
    "children" : [ ]
  }, {
    "dbId" : 29372,
    "stId" : "R-ALL-29372",
    "displayName" : "Pi [cytosol]",
    "schemaClass" : "SimpleEntity",
    "speciesId" : 0,
    "diagramIds" : [ 136469, 136485, 136475, 136460 ],
    "identifier" : "43474",
    "standardIdentifier" : "chebi:43474",
    "referenceType" : "ReferenceMolecule",
    "parents" : [ ],
    "children" : [ ]
  }, {
    "dbId" : 10713054,
    "stId" : "R-XTR-8854278",
    "displayName" : "OPTN:RAB8:GTP [recycling endosome membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 205621,
    "diagramIds" : [ 136479 ],
    "parents" : [ 10713060 ],
    "children" : [ 10713052, 10713042 ]
  }, {
    "dbId" : 29438,
    "stId" : "R-ALL-29438",
    "displayName" : "GTP [cytosol]",
    "schemaClass" : "SimpleEntity",
    "speciesId" : 0,
    "identifier" : "37565",
    "standardIdentifier" : "chebi:37565",
    "referenceType" : "ReferenceMolecule",
    "parents" : [ 10713030, 10713106, 10713052 ],
    "children" : [ ]
  }, {
    "dbId" : 10713052,
    "stId" : "R-XTR-8854190",
    "displayName" : "RAB8:GTP [recycling endosome membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 205621,
    "parents" : [ 10713054 ],
    "children" : [ 29438, 10713050 ]
  } ],
  "edges" : [ {
    "dbId" : 10713075,
    "stId" : "R-XTR-8854255",
    "displayName" : "TBC1D2A accelerates GTP hydrolysis by RAB7",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "inputs" : [ 10713070, 29356 ],
    "outputs" : [ 29372, 10713072 ],
    "catalysts" : [ 10713070 ],
    "efs" : [ ],
    "diagramIds" : [ 136456 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10713091,
    "stId" : "R-XTR-8854329",
    "displayName" : "TBC1D15 accelerates GTP hydrolysis by RAB7",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "inputs" : [ 10713070, 29356 ],
    "outputs" : [ 10713085, 29372 ],
    "catalysts" : [ 10713070 ],
    "efs" : [ ],
    "activators" : [ 10713089 ],
    "diagramIds" : [ 136471 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10713111,
    "stId" : "R-XTR-8854612",
    "displayName" : "TBC1D25 accelerates GTP hydrolysis by RAB33B",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "inputs" : [ 29356, 10713106 ],
    "outputs" : [ 29372, 10713108 ],
    "catalysts" : [ 10713106 ],
    "efs" : [ ],
    "diagramIds" : [ 136481 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10713062,
    "stId" : "R-XTR-8854182",
    "displayName" : "TBC1D17 binds OPTN:RAB8A",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "inputs" : [ 10713054, 10713058 ],
    "outputs" : [ 10713060 ],
    "efs" : [ ],
    "diagramIds" : [ 136477 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10713083,
    "stId" : "R-XTR-8854302",
    "displayName" : "TBC1D7 binds the TSC1-TSC2 complex",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "inputs" : [ 10660685, 10713079 ],
    "outputs" : [ 10713081 ],
    "efs" : [ ],
    "diagramIds" : [ 136461 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10713039,
    "stId" : "R-XTR-8854173",
    "displayName" : "TBC RabGAPs accelerate GTP hydrolysis by RAB35",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "inputs" : [ 29356, 10713030 ],
    "outputs" : [ 29372, 10713032 ],
    "catalysts" : [ 10713030 ],
    "efs" : [ ],
    "activators" : [ 10713037 ],
    "diagramIds" : [ 136465 ],
    "entityFunctionalStatus" : [ ]
  } ]
}