{
  "dbId" : 10729320,
  "stId" : "R-XTR-2559585",
  "speciesName" : "Xenopus tropicalis",
  "nodes" : [ {
    "dbId" : 10692451,
    "stId" : "R-XTR-3132724",
    "displayName" : "p-T38-ETS1/ p-T72-ETS2 [nucleoplasm]",
    "schemaClass" : "DefinedSet",
    "speciesId" : 205621,
    "diagramIds" : [ 93932 ],
    "parents" : [ ],
    "children" : [ 10692446, 10692449 ]
  }, {
    "dbId" : 10692449,
    "stId" : "R-XTR-3132735",
    "displayName" : "phospho-ets2 [nucleoplasm]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 205621,
    "diagramIds" : [ 93948 ],
    "identifier" : "B1WAP2",
    "standardIdentifier" : "uniprot:B1WAP2",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "ets2" ],
    "parents" : [ 10692451 ],
    "children" : [ ]
  }, {
    "dbId" : 10662756,
    "stId" : "R-XTR-182586",
    "displayName" : "cdkn2b [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 205621,
    "identifier" : "Q6DIG7",
    "standardIdentifier" : "uniprot:Q6DIG7",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "cdkn2b" ],
    "parents" : [ 10662774 ],
    "children" : [ ]
  }, {
    "dbId" : 10662762,
    "stId" : "R-XTR-182578-2",
    "displayName" : "cdkn2b [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 205621,
    "diagramIds" : [ 93944 ],
    "identifier" : "Q6DIG7",
    "standardIdentifier" : "uniprot:Q6DIG7",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "cdkn2b" ],
    "parents" : [ 10662764 ],
    "children" : [ ]
  }, {
    "dbId" : 10662760,
    "stId" : "R-XTR-182578",
    "displayName" : "LOC100488442 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 205621,
    "identifier" : "A0A803JN89",
    "standardIdentifier" : "uniprot:A0A803JN89",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "LOC100488442" ],
    "parents" : [ 10662764 ],
    "children" : [ ]
  }, {
    "dbId" : 10662764,
    "stId" : "R-XTR-182578-3",
    "displayName" : "Homologues of p16INK4A [cytosol]",
    "schemaClass" : "DefinedSet",
    "speciesId" : 205621,
    "parents" : [ 10662774 ],
    "children" : [ 10662760, 10662762 ]
  }, {
    "dbId" : 10692595,
    "stId" : "R-XTR-3209167",
    "displayName" : "phospho-erf [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 205621,
    "diagramIds" : [ 93940 ],
    "identifier" : "Q5EB35",
    "standardIdentifier" : "uniprot:Q5EB35",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "erf" ],
    "parents" : [ ],
    "children" : [ ]
  }, {
    "dbId" : 10664755,
    "stId" : "R-XTR-112354",
    "displayName" : "phospho-p-T185,Y187-MAPK1 [nucleoplasm]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 205621,
    "identifier" : "Q28H11",
    "standardIdentifier" : "uniprot:Q28H11",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 10664757 ],
    "children" : [ ]
  }, {
    "dbId" : 10692593,
    "stId" : "R-XTR-3209166",
    "displayName" : "phospho-erf [nucleoplasm]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 205621,
    "diagramIds" : [ 93939 ],
    "identifier" : "Q5EB35",
    "standardIdentifier" : "uniprot:Q5EB35",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "erf" ],
    "parents" : [ ],
    "children" : [ ]
  }, {
    "dbId" : 10662768,
    "stId" : "R-XTR-182572",
    "displayName" : "cdkn2c [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 205621,
    "identifier" : "B1H1E7",
    "standardIdentifier" : "uniprot:B1H1E7",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "cdkn2c" ],
    "parents" : [ 10662774 ],
    "children" : [ ]
  }, {
    "dbId" : 10662774,
    "stId" : "R-XTR-182588",
    "displayName" : "INK4 [cytosol]",
    "schemaClass" : "DefinedSet",
    "speciesId" : 205621,
    "diagramIds" : [ 93935 ],
    "parents" : [ 10662780 ],
    "children" : [ 10662764, 10662772, 10662756, 10662768 ]
  }, {
    "dbId" : 10728374,
    "stId" : "R-XTR-453279",
    "displayName" : "Mitotic G1 phase and G1/S transition",
    "schemaClass" : "Pathway",
    "speciesId" : 205621,
    "diagramIds" : [ 93945 ]
  }, {
    "dbId" : 10728886,
    "stId" : "R-XTR-109606",
    "displayName" : "Intrinsic Pathway for Apoptosis",
    "schemaClass" : "Pathway",
    "speciesId" : 205621,
    "diagramIds" : [ 93953 ]
  }, {
    "dbId" : 10662772,
    "stId" : "R-XTR-182580",
    "displayName" : "cdkn2d [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 205621,
    "identifier" : "Q0P4P6",
    "standardIdentifier" : "uniprot:Q0P4P6",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "cdkn2d" ],
    "parents" : [ 10662774 ],
    "children" : [ ]
  }, {
    "dbId" : 10664757,
    "stId" : "R-XTR-109856",
    "displayName" : "p-Y185,Y187 MAPK1 dimer [nucleoplasm]",
    "schemaClass" : "Complex",
    "speciesId" : 205621,
    "diagramIds" : [ 93933 ],
    "parents" : [ ],
    "children" : [ 10664755 ]
  }, {
    "dbId" : 10662778,
    "stId" : "R-XTR-69209",
    "displayName" : "CDK4,CDK6 [cytosol]",
    "schemaClass" : "DefinedSet",
    "speciesId" : 205621,
    "diagramIds" : [ 93936 ],
    "parents" : [ 10662780 ],
    "children" : [ 10662776, 10655947 ]
  }, {
    "dbId" : 10662776,
    "stId" : "R-XTR-68336",
    "displayName" : "CDK6 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 205621,
    "identifier" : "F6YRJ4",
    "standardIdentifier" : "uniprot:F6YRJ4",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 10662778 ],
    "children" : [ ]
  }, {
    "dbId" : 10729144,
    "stId" : "R-XTR-2559580",
    "displayName" : "Oxidative Stress Induced Senescence",
    "schemaClass" : "Pathway",
    "speciesId" : 205621,
    "diagramIds" : [ 93954 ]
  }, {
    "dbId" : 10662780,
    "stId" : "R-XTR-182579",
    "displayName" : "CDK4,CDK6:INK4 [cytosol]",
    "schemaClass" : "Complex",
    "speciesId" : 205621,
    "diagramIds" : [ 93937 ],
    "parents" : [ ],
    "children" : [ 10662778, 10662774 ]
  }, {
    "dbId" : 10655947,
    "stId" : "R-XTR-68330",
    "displayName" : "CDK4 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 205621,
    "identifier" : "Q28J99",
    "standardIdentifier" : "uniprot:Q28J99",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 10662778 ],
    "children" : [ ]
  }, {
    "dbId" : 29358,
    "stId" : "R-ALL-29358",
    "displayName" : "ATP [nucleoplasm]",
    "schemaClass" : "SimpleEntity",
    "speciesId" : 0,
    "diagramIds" : [ 93930 ],
    "identifier" : "30616",
    "standardIdentifier" : "chebi:30616",
    "referenceType" : "ReferenceMolecule",
    "parents" : [ ],
    "children" : [ ]
  }, {
    "dbId" : 113582,
    "stId" : "R-ALL-113582",
    "displayName" : "ADP [nucleoplasm]",
    "schemaClass" : "SimpleEntity",
    "speciesId" : 0,
    "diagramIds" : [ 93931 ],
    "identifier" : "456216",
    "standardIdentifier" : "chebi:456216",
    "referenceType" : "ReferenceMolecule",
    "parents" : [ ],
    "children" : [ ]
  }, {
    "dbId" : 10692437,
    "stId" : "R-XTR-1629809",
    "displayName" : "ets1 [nucleoplasm]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 205621,
    "identifier" : "B3DM35",
    "standardIdentifier" : "uniprot:B3DM35",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "ets1" ],
    "parents" : [ 10692443 ],
    "children" : [ ]
  }, {
    "dbId" : 10692443,
    "stId" : "R-XTR-3132719",
    "displayName" : "ETS1/ETS2 [nucleoplasm]",
    "schemaClass" : "DefinedSet",
    "speciesId" : 205621,
    "diagramIds" : [ 93929 ],
    "parents" : [ ],
    "children" : [ 10692441, 10692437 ]
  }, {
    "dbId" : 10728410,
    "stId" : "R-XTR-2559586",
    "displayName" : "DNA Damage/Telomere Stress Induced Senescence",
    "schemaClass" : "Pathway",
    "speciesId" : 205621,
    "diagramIds" : [ 93955 ]
  }, {
    "dbId" : 10692441,
    "stId" : "R-XTR-1629811",
    "displayName" : "ets2 [nucleoplasm]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 205621,
    "diagramIds" : [ 93951 ],
    "identifier" : "B1WAP2",
    "standardIdentifier" : "uniprot:B1WAP2",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "ets2" ],
    "parents" : [ 10692443 ],
    "children" : [ ]
  }, {
    "dbId" : 10728408,
    "stId" : "R-XTR-69620",
    "displayName" : "Cell Cycle Checkpoints",
    "schemaClass" : "Pathway",
    "speciesId" : 205621,
    "diagramIds" : [ 93956 ]
  }, {
    "dbId" : 10692446,
    "stId" : "R-XTR-3132720",
    "displayName" : "phospho-ets1 [nucleoplasm]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 205621,
    "diagramIds" : [ 93960 ],
    "identifier" : "B3DM35",
    "standardIdentifier" : "uniprot:B3DM35",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "ets1" ],
    "parents" : [ 10692451 ],
    "children" : [ ]
  } ],
  "edges" : [ {
    "dbId" : 10692453,
    "stId" : "R-XTR-3132737",
    "displayName" : "MAPKs phosphorylate ETS1 and ETS2",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "inputs" : [ 29358, 10692443 ],
    "outputs" : [ 113582, 10692451 ],
    "catalysts" : [ 10664757 ],
    "efs" : [ ],
    "diagramIds" : [ 93928 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10692597,
    "stId" : "R-XTR-3209159",
    "displayName" : "Phosphorylated ERF translocates to the cytosol",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "inputs" : [ 10692593 ],
    "outputs" : [ 10692595 ],
    "efs" : [ ],
    "diagramIds" : [ 93938 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10662782,
    "stId" : "R-XTR-182594",
    "displayName" : "Association of INK4 family proteins with CDK4/6",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "inputs" : [ 10662778, 10662774 ],
    "outputs" : [ 10662780 ],
    "efs" : [ ],
    "diagramIds" : [ 93934 ],
    "entityFunctionalStatus" : [ ]
  } ]
}