{
  "dbId" : 10650672,
  "stId" : "R-DRE-9839373",
  "speciesName" : "Danio rerio",
  "nodes" : [ {
    "dbId" : 10649378,
    "stId" : "R-DRE-1502540",
    "displayName" : "Signaling by Activin",
    "schemaClass" : "Pathway",
    "speciesId" : 68323,
    "diagramIds" : [ 103285 ]
  }, {
    "dbId" : 10571296,
    "stId" : "R-DRE-9839334",
    "displayName" : "TGFBR3(1-783):TGFB1,TGFB2 [extracellular region]",
    "schemaClass" : "Complex",
    "speciesId" : 68323,
    "diagramIds" : [ 103246 ],
    "parents" : [ ],
    "children" : [ 10571294, 10571269 ]
  }, {
    "dbId" : 10587939,
    "stId" : "R-DRE-349743",
    "displayName" : "TIMP1 [extracellular region]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 68323,
    "identifier" : "Q6NUX9",
    "standardIdentifier" : "uniprot:Q6NUX9",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 10587943 ],
    "children" : [ ]
  }, {
    "dbId" : 10587941,
    "stId" : "R-DRE-349743-2",
    "displayName" : "TIMP1 [extracellular region]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 68323,
    "identifier" : "Q7SZM6",
    "standardIdentifier" : "uniprot:Q7SZM6",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 10587943 ],
    "children" : [ ]
  }, {
    "dbId" : 10648484,
    "stId" : "R-DRE-5654736",
    "displayName" : "Signaling by FGFR1",
    "schemaClass" : "Pathway",
    "speciesId" : 68323,
    "diagramIds" : [ 103286 ]
  }, {
    "dbId" : 10587943,
    "stId" : "R-DRE-349743-3",
    "displayName" : "Homologues of TIMP1 [extracellular region]",
    "schemaClass" : "DefinedSet",
    "speciesId" : 68323,
    "diagramIds" : [ 103239 ],
    "parents" : [ ],
    "children" : [ 10587941, 10587939 ]
  }, {
    "dbId" : 10583979,
    "stId" : "R-DRE-264470",
    "displayName" : "arrb1 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 68323,
    "identifier" : "C3PTE8",
    "standardIdentifier" : "uniprot:C3PTE8",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "arrb1" ],
    "parents" : [ 10614041 ],
    "children" : [ ]
  }, {
    "dbId" : 10565933,
    "stId" : "R-DRE-189898",
    "displayName" : "fgf2 [extracellular region]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 68323,
    "diagramIds" : [ 103274 ],
    "identifier" : "B3DGE3",
    "standardIdentifier" : "uniprot:B3DGE3",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "fgf2" ],
    "parents" : [ 10572939 ],
    "children" : [ ]
  }, {
    "dbId" : 10571192,
    "stId" : "R-DRE-170842",
    "displayName" : "TGFBR2 [plasma membrane]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 68323,
    "diagramIds" : [ 103249 ],
    "identifier" : "Q58EQ1",
    "standardIdentifier" : "uniprot:Q58EQ1",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 10643553, 10571273, 10571194 ],
    "children" : [ ]
  }, {
    "dbId" : 10571194,
    "stId" : "R-DRE-170866",
    "displayName" : "TGFBR2 homodimer [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 68323,
    "parents" : [ 10571238 ],
    "children" : [ 10571192 ]
  }, {
    "dbId" : 10571198,
    "stId" : "R-DRE-170838",
    "displayName" : "tgfb1a [extracellular region]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 68323,
    "identifier" : "Q7ZZU7",
    "standardIdentifier" : "uniprot:Q7ZZU7",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "tgfb1a" ],
    "parents" : [ 10571269, 10571200 ],
    "children" : [ ]
  }, {
    "dbId" : 10571267,
    "stId" : "R-DRE-114706",
    "displayName" : "tgfb2 [extracellular region]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 68323,
    "identifier" : "Q7SZV4",
    "standardIdentifier" : "uniprot:Q7SZV4",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "tgfb2" ],
    "parents" : [ 10571269 ],
    "children" : [ ]
  }, {
    "dbId" : 10571269,
    "stId" : "R-DRE-9839339",
    "displayName" : "TGFB1,TGFB2 [extracellular region]",
    "schemaClass" : "DefinedSet",
    "speciesId" : 68323,
    "diagramIds" : [ 103243 ],
    "parents" : [ 10643553, 10571296, 10571271 ],
    "children" : [ 10571198, 10571267 ]
  }, {
    "dbId" : 10643588,
    "stId" : "R-DRE-9839374",
    "displayName" : "tgfbr3 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 68323,
    "diagramIds" : [ 103232 ],
    "identifier" : "A0A0H3UK16",
    "standardIdentifier" : "uniprot:A0A0H3UK16",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "tgfbr3" ],
    "parents" : [ ],
    "children" : [ ]
  }, {
    "dbId" : 10571271,
    "stId" : "R-DRE-9839342",
    "displayName" : "TGFB1,TGFB2:TGFBR3 [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 68323,
    "diagramIds" : [ 103245 ],
    "parents" : [ 10643594, 10571273 ],
    "children" : [ 10571263, 10571269 ]
  }, {
    "dbId" : 10571273,
    "stId" : "R-DRE-9839341",
    "displayName" : "TGFB1,TGFB2:TGFBR3:TGFBR2 [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 68323,
    "diagramIds" : [ 103250 ],
    "parents" : [ ],
    "children" : [ 10571192, 10571271 ]
  }, {
    "dbId" : 10643594,
    "stId" : "R-DRE-9839403",
    "displayName" : "TGFB1,TGFB2:TGFBR3:GIPC1 [cytoplasmic side of plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 68323,
    "diagramIds" : [ 103261 ],
    "parents" : [ ],
    "children" : [ 10572943, 10571271 ]
  }, {
    "dbId" : 10572939,
    "stId" : "R-DRE-9839344",
    "displayName" : "FGF2:TGFBR3 [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 68323,
    "diagramIds" : [ 103276 ],
    "parents" : [ 10572945 ],
    "children" : [ 10571263, 10565933 ]
  }, {
    "dbId" : 10575629,
    "stId" : "R-DRE-1449702",
    "displayName" : "inha [extracellular region]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 68323,
    "identifier" : "Q1LYE4",
    "standardIdentifier" : "uniprot:Q1LYE4",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "inha" ],
    "parents" : [ 10575635 ],
    "children" : [ ]
  }, {
    "dbId" : 10572943,
    "stId" : "R-DRE-9839329",
    "displayName" : "gipc1 [cytoplasm]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 68323,
    "diagramIds" : [ 103260, 103278 ],
    "identifier" : "Q6B337",
    "standardIdentifier" : "uniprot:Q6B337",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "gipc1" ],
    "parents" : [ 10643594, 10572945 ],
    "children" : [ ]
  }, {
    "dbId" : 10575633,
    "stId" : "R-DRE-205926",
    "displayName" : "inhbaa [extracellular region]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 68323,
    "identifier" : "Q8QGE3",
    "standardIdentifier" : "uniprot:Q8QGE3",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "inhbaa" ],
    "parents" : [ 10575635 ],
    "children" : [ ]
  }, {
    "dbId" : 10572945,
    "stId" : "R-DRE-9839332",
    "displayName" : "FGF2:TGFBR3:GIPC1 [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 68323,
    "diagramIds" : [ 103279 ],
    "parents" : [ ],
    "children" : [ 10572943, 10572939 ]
  }, {
    "dbId" : 10575635,
    "stId" : "R-DRE-9839337",
    "displayName" : "INHIBIN-A [extracellular region]",
    "schemaClass" : "Complex",
    "speciesId" : 68323,
    "diagramIds" : [ 103267 ],
    "parents" : [ 10575637 ],
    "children" : [ 10575629, 10575633 ]
  }, {
    "dbId" : 10575637,
    "stId" : "R-DRE-9839340",
    "displayName" : "INHIBIN-A:TGFBR3 [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 68323,
    "diagramIds" : [ 103269 ],
    "parents" : [ 10575639 ],
    "children" : [ 10571263, 10575635 ]
  }, {
    "dbId" : 10595732,
    "stId" : "R-DRE-1442472",
    "displayName" : "MMP14 [plasma membrane]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 68323,
    "identifier" : "B0R0I1",
    "standardIdentifier" : "uniprot:B0R0I1",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 10596694 ],
    "children" : [ ]
  }, {
    "dbId" : 10648340,
    "stId" : "R-DRE-170834",
    "displayName" : "Signaling by TGF-beta Receptor Complex",
    "schemaClass" : "Pathway",
    "speciesId" : 68323,
    "diagramIds" : [ 103287 ]
  }, {
    "dbId" : 10575639,
    "stId" : "R-DRE-9839343",
    "displayName" : "INHIBIN-A:TGFBR3:ACVR2A [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 68323,
    "diagramIds" : [ 103272 ],
    "parents" : [ ],
    "children" : [ 10575564, 10575637 ]
  }, {
    "dbId" : 10614041,
    "stId" : "R-DRE-1911410",
    "displayName" : "ARRB [cytosol]",
    "schemaClass" : "DefinedSet",
    "speciesId" : 68323,
    "diagramIds" : [ 103257 ],
    "parents" : [ 10643555 ],
    "children" : [ 10583979, 10584002 ]
  }, {
    "dbId" : 113592,
    "stId" : "R-ALL-113592",
    "displayName" : "ATP [cytosol]",
    "schemaClass" : "SimpleEntity",
    "speciesId" : 0,
    "diagramIds" : [ 103252 ],
    "identifier" : "30616",
    "standardIdentifier" : "chebi:30616",
    "referenceType" : "ReferenceMolecule",
    "parents" : [ ],
    "children" : [ ]
  }, {
    "dbId" : 29370,
    "stId" : "R-ALL-29370",
    "displayName" : "ADP [cytosol]",
    "schemaClass" : "SimpleEntity",
    "speciesId" : 0,
    "diagramIds" : [ 103254 ],
    "identifier" : "456216",
    "standardIdentifier" : "chebi:456216",
    "referenceType" : "ReferenceMolecule",
    "parents" : [ ],
    "children" : [ ]
  }, {
    "dbId" : 10571294,
    "stId" : "R-DRE-9839335",
    "displayName" : "tgfbr3 [extracellular region]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 68323,
    "diagramIds" : [ 103235 ],
    "identifier" : "A0A0H3UK16",
    "standardIdentifier" : "uniprot:A0A0H3UK16",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "tgfbr3" ],
    "parents" : [ 10571296 ],
    "children" : [ ]
  }, {
    "dbId" : 10573665,
    "stId" : "R-DRE-9013329",
    "displayName" : "psen2 [plasma membrane]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 68323,
    "identifier" : "Q90ZE4",
    "standardIdentifier" : "uniprot:Q90ZE4",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "psen2" ],
    "parents" : [ 10573667 ],
    "children" : [ ]
  }, {
    "dbId" : 10643555,
    "stId" : "R-DRE-9839392",
    "displayName" : "pTGFBR3-complex:ARRB [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 68323,
    "diagramIds" : [ 103258 ],
    "parents" : [ ],
    "children" : [ 10614041, 10643553 ]
  }, {
    "dbId" : 10573667,
    "stId" : "R-DRE-157352",
    "displayName" : "PSEN2 [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 68323,
    "parents" : [ 10573677 ],
    "children" : [ 10573663, 10573665 ]
  }, {
    "dbId" : 10643553,
    "stId" : "R-DRE-9839395",
    "displayName" : "TGFB1,TGFB2:pTGFBR3:TGFBR2 [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 68323,
    "diagramIds" : [ 103253 ],
    "parents" : [ 10643561, 10643555 ],
    "children" : [ 10571263, 10571192, 10571269 ]
  }, {
    "dbId" : 10571234,
    "stId" : "R-DRE-170839",
    "displayName" : "TGFBR1 [plasma membrane]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 68323,
    "identifier" : "B0EXP7",
    "standardIdentifier" : "uniprot:B0EXP7",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 10571236 ],
    "children" : [ ]
  }, {
    "dbId" : 10643559,
    "stId" : "R-DRE-9910882",
    "displayName" : "arrb1 [endocytic vesicle membrane]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 68323,
    "identifier" : "C3PTE8",
    "standardIdentifier" : "uniprot:C3PTE8",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "arrb1" ],
    "parents" : [ 10643561 ],
    "children" : [ ]
  }, {
    "dbId" : 10571236,
    "stId" : "R-DRE-170864",
    "displayName" : "TGFBR1 homodimer [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 68323,
    "parents" : [ 10571238 ],
    "children" : [ 10571234 ]
  }, {
    "dbId" : 10573671,
    "stId" : "R-DRE-2534245",
    "displayName" : "psen1 [plasma membrane]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 68323,
    "identifier" : "Q9W6T7",
    "standardIdentifier" : "uniprot:Q9W6T7",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "psen1" ],
    "parents" : [ 10573675 ],
    "children" : [ ]
  }, {
    "dbId" : 10643557,
    "stId" : "R-DRE-9910881",
    "displayName" : "arrb2a [endocytic vesicle membrane]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 68323,
    "identifier" : "A0A286YBG8",
    "standardIdentifier" : "uniprot:A0A286YBG8",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "arrb2a" ],
    "parents" : [ 10643561 ],
    "children" : [ ]
  }, {
    "dbId" : 10571238,
    "stId" : "R-DRE-170840",
    "displayName" : "TGFB1:TGFBR2:TGFBR1 [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 68323,
    "diagramIds" : [ 103255 ],
    "parents" : [ ],
    "children" : [ 10571194, 10571236, 10571200 ]
  }, {
    "dbId" : 10573673,
    "stId" : "R-DRE-2534298",
    "displayName" : "psen1 [plasma membrane]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 68323,
    "identifier" : "Q9W6T7",
    "standardIdentifier" : "uniprot:Q9W6T7",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "psen1" ],
    "parents" : [ 10573675 ],
    "children" : [ ]
  }, {
    "dbId" : 10573675,
    "stId" : "R-DRE-2534316",
    "displayName" : "PSEN1 [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 68323,
    "parents" : [ 10573677 ],
    "children" : [ 10573673, 10573671 ]
  }, {
    "dbId" : 10643561,
    "stId" : "R-DRE-9839399",
    "displayName" : "pTGFBR3-complex:ARBB_endo [endocytic vesicle membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 68323,
    "diagramIds" : [ 103263 ],
    "parents" : [ ],
    "children" : [ 10643557, 10643559, 10643553 ]
  }, {
    "dbId" : 10573677,
    "stId" : "R-DRE-9013333",
    "displayName" : "Presenilin [plasma membrane]",
    "schemaClass" : "DefinedSet",
    "speciesId" : 68323,
    "parents" : [ 10573679 ],
    "children" : [ 10573675, 10573667 ]
  }, {
    "dbId" : 10573679,
    "stId" : "R-DRE-157343",
    "displayName" : "gamma-secretase complex [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 68323,
    "diagramIds" : [ 103241 ],
    "parents" : [ ],
    "children" : [ 10573677, 10573645, 10573659, 10573655 ]
  }, {
    "dbId" : 10643568,
    "stId" : "R-DRE-9839380",
    "displayName" : "tgfbr3 [basolateral plasma membrane]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 68323,
    "diagramIds" : [ 103236 ],
    "identifier" : "A0A0H3UK16",
    "standardIdentifier" : "uniprot:A0A0H3UK16",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "tgfbr3" ],
    "parents" : [ ],
    "children" : [ ]
  }, {
    "dbId" : 10596470,
    "stId" : "R-DRE-1454879",
    "displayName" : "TIMP2 [extracellular region]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 68323,
    "diagramIds" : [ 103238 ],
    "identifier" : "Q7SZM6",
    "standardIdentifier" : "uniprot:Q7SZM6",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ ],
    "children" : [ ]
  }, {
    "dbId" : 10648696,
    "stId" : "R-DRE-201451",
    "displayName" : "Signaling by BMP",
    "schemaClass" : "Pathway",
    "speciesId" : 68323,
    "diagramIds" : [ 103288 ]
  }, {
    "dbId" : 10571263,
    "stId" : "R-DRE-9839336",
    "displayName" : "tgfbr3 [plasma membrane]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 68323,
    "diagramIds" : [ 103233, 103265, 103268, 103275, 103244 ],
    "identifier" : "A0A0H3UK16",
    "standardIdentifier" : "uniprot:A0A0H3UK16",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "tgfbr3" ],
    "parents" : [ 10643553, 10575637, 10571271, 10572939 ],
    "children" : [ ]
  }, {
    "dbId" : 10571200,
    "stId" : "R-DRE-170852",
    "displayName" : "Dimeric TGFB1 [extracellular region]",
    "schemaClass" : "Complex",
    "speciesId" : 68323,
    "parents" : [ 10571238 ],
    "children" : [ 10571198 ]
  }, {
    "dbId" : 10584002,
    "stId" : "R-DRE-416464",
    "displayName" : "arrb2a [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 68323,
    "identifier" : "A0A286YBG8",
    "standardIdentifier" : "uniprot:A0A286YBG8",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "arrb2a" ],
    "parents" : [ 10614041 ],
    "children" : [ ]
  }, {
    "dbId" : 10573645,
    "stId" : "R-DRE-157331",
    "displayName" : "psenen [plasma membrane]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 68323,
    "identifier" : "Q8JHF0",
    "standardIdentifier" : "uniprot:Q8JHF0",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "psenen" ],
    "parents" : [ 10573679 ],
    "children" : [ ]
  }, {
    "dbId" : 10575564,
    "stId" : "R-DRE-201659",
    "displayName" : "acvr2ab [plasma membrane]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 68323,
    "diagramIds" : [ 103271 ],
    "identifier" : "A0A0R4ISZ9",
    "standardIdentifier" : "uniprot:A0A0R4ISZ9",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "acvr2ab" ],
    "parents" : [ 10575639 ],
    "children" : [ ]
  }, {
    "dbId" : 10573649,
    "stId" : "R-DRE-157340",
    "displayName" : "aph1b [plasma membrane]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 68323,
    "identifier" : "Q8JHE9",
    "standardIdentifier" : "uniprot:Q8JHE9",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "aph1b" ],
    "parents" : [ 10573655 ],
    "children" : [ ]
  }, {
    "dbId" : 10573653,
    "stId" : "R-DRE-3211581",
    "displayName" : "APH1A [plasma membrane]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 68323,
    "identifier" : "Q4V8Q7",
    "standardIdentifier" : "uniprot:Q4V8Q7",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 10573655 ],
    "children" : [ ]
  }, {
    "dbId" : 10596692,
    "stId" : "R-DRE-1605818",
    "displayName" : "MMP16 [plasma membrane]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 68323,
    "identifier" : "F1R8N4",
    "standardIdentifier" : "uniprot:F1R8N4",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 10596694 ],
    "children" : [ ]
  }, {
    "dbId" : 10573655,
    "stId" : "R-DRE-157341",
    "displayName" : "APH-1 [plasma membrane]",
    "schemaClass" : "DefinedSet",
    "speciesId" : 68323,
    "parents" : [ 10573679 ],
    "children" : [ 10573653, 10573649 ]
  }, {
    "dbId" : 10596694,
    "stId" : "R-DRE-1629856",
    "displayName" : "MMP14 (16) [plasma membrane]",
    "schemaClass" : "CandidateSet",
    "speciesId" : 68323,
    "diagramIds" : [ 103237 ],
    "parents" : [ ],
    "children" : [ 10595732, 10596692 ]
  }, {
    "dbId" : 10573659,
    "stId" : "R-DRE-2534241",
    "displayName" : "ncstn [plasma membrane]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 68323,
    "identifier" : "Q5XLR3",
    "standardIdentifier" : "uniprot:Q5XLR3",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "ncstn" ],
    "parents" : [ 10573679 ],
    "children" : [ ]
  }, {
    "dbId" : 10573663,
    "stId" : "R-DRE-201599",
    "displayName" : "psen2 [plasma membrane]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 68323,
    "identifier" : "Q90ZE4",
    "standardIdentifier" : "uniprot:Q90ZE4",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "psen2" ],
    "parents" : [ 10573667 ],
    "children" : [ ]
  } ],
  "edges" : [ {
    "dbId" : 10643586,
    "stId" : "R-DRE-9839384",
    "displayName" : "Inhibin-A binding to TGFBR3",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "preceding" : [ 10643590 ],
    "following" : [ 10643601 ],
    "inputs" : [ 10571263, 10575635 ],
    "outputs" : [ 10575637 ],
    "efs" : [ ],
    "diagramIds" : [ 103266 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10643584,
    "stId" : "R-DRE-9839381",
    "displayName" : "FGF2:TGFBR3 binding to GIPC1",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "preceding" : [ 10643582 ],
    "inputs" : [ 10572943, 10572939 ],
    "outputs" : [ 10572945 ],
    "efs" : [ ],
    "diagramIds" : [ 103277 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10643590,
    "stId" : "R-DRE-9839388",
    "displayName" : "TGFBR3 translocation to plasma membrane",
    "schemaClass" : "BlackBoxEvent",
    "speciesId" : 0,
    "following" : [ 10643596, 10643578, 10643586, 10643582, 10643570 ],
    "inputs" : [ 10643588 ],
    "outputs" : [ 10571263 ],
    "efs" : [ ],
    "diagramIds" : [ 103231 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10643563,
    "stId" : "R-DRE-9839358",
    "displayName" : "Endocytosis of TGFBR3:ARRB complex",
    "schemaClass" : "BlackBoxEvent",
    "speciesId" : 0,
    "preceding" : [ 10643580 ],
    "inputs" : [ 10643555 ],
    "outputs" : [ 10643561 ],
    "efs" : [ ],
    "diagramIds" : [ 103262 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10643592,
    "stId" : "R-DRE-9839390",
    "displayName" : "TGFBR3 complex binds to TGFBR2",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "preceding" : [ 10643578 ],
    "following" : [ 10643566 ],
    "inputs" : [ 10571192, 10571271 ],
    "outputs" : [ 10571273 ],
    "efs" : [ ],
    "diagramIds" : [ 103248 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10643566,
    "stId" : "R-DRE-9839363",
    "displayName" : "TGFBR3 phosphorylation by TGFBR2 complex",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "preceding" : [ 10643592 ],
    "following" : [ 10643580 ],
    "inputs" : [ 113592, 10571273 ],
    "outputs" : [ 29370, 10643553 ],
    "catalysts" : [ 10571238 ],
    "efs" : [ ],
    "diagramIds" : [ 103251 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10643599,
    "stId" : "R-DRE-9839402",
    "displayName" : "TGFBR3 binding to GIPC1",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "preceding" : [ 10643578 ],
    "inputs" : [ 10572943, 10571271 ],
    "outputs" : [ 10643594 ],
    "efs" : [ ],
    "diagramIds" : [ 103259 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10643596,
    "stId" : "R-DRE-9839401",
    "displayName" : "TGFBR3 degradation",
    "schemaClass" : "BlackBoxEvent",
    "speciesId" : 0,
    "preceding" : [ 10643590 ],
    "inputs" : [ 10571263 ],
    "efs" : [ ],
    "inhibitors" : [ 10643594 ],
    "diagramIds" : [ 103264 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10643570,
    "stId" : "R-DRE-9839367",
    "displayName" : "TGFBR3_mem cleavage by MMPs",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "preceding" : [ 10643590 ],
    "following" : [ 10643574, 10643576 ],
    "inputs" : [ 10571263 ],
    "outputs" : [ 10571294, 10643568 ],
    "catalysts" : [ 10596694 ],
    "efs" : [ ],
    "inhibitors" : [ 10596470, 10587943 ],
    "diagramIds" : [ 103234 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10643601,
    "stId" : "R-DRE-9839405",
    "displayName" : "InhibinA-TGFBR3 binding to ACVR2A",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "preceding" : [ 10643586 ],
    "inputs" : [ 10575564, 10575637 ],
    "outputs" : [ 10575639 ],
    "efs" : [ ],
    "diagramIds" : [ 103270 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10643574,
    "stId" : "R-DRE-9839368",
    "displayName" : "TGFBR3(1-783) binds to TGFB1,TGFB2",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "preceding" : [ 10643570 ],
    "inputs" : [ 10571294, 10571269 ],
    "outputs" : [ 10571296 ],
    "efs" : [ ],
    "diagramIds" : [ 103247 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10643578,
    "stId" : "R-DRE-9839377",
    "displayName" : "TGFB1,TGFB2 bind TGFBR3",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "preceding" : [ 10643590 ],
    "following" : [ 10643599, 10643592 ],
    "inputs" : [ 10571263, 10571269 ],
    "outputs" : [ 10571271 ],
    "efs" : [ ],
    "inhibitors" : [ 10571296 ],
    "diagramIds" : [ 103242 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10643576,
    "stId" : "R-DRE-9839376",
    "displayName" : "TGFBR3(784-851) degradation",
    "schemaClass" : "BlackBoxEvent",
    "speciesId" : 0,
    "preceding" : [ 10643570 ],
    "inputs" : [ 10643568 ],
    "catalysts" : [ 10573679 ],
    "efs" : [ ],
    "diagramIds" : [ 103240 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10643582,
    "stId" : "R-DRE-9839379",
    "displayName" : "TGFBR3 binding to FGF2",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "preceding" : [ 10643590 ],
    "following" : [ 10643584 ],
    "inputs" : [ 10571263, 10565933 ],
    "outputs" : [ 10572939 ],
    "efs" : [ ],
    "diagramIds" : [ 103273 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10643580,
    "stId" : "R-DRE-9839378",
    "displayName" : "TGFBR3 binding to ARRB1/2",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "preceding" : [ 10643566 ],
    "following" : [ 10643563 ],
    "inputs" : [ 10614041, 10643553 ],
    "outputs" : [ 10643555 ],
    "efs" : [ ],
    "diagramIds" : [ 103256 ],
    "entityFunctionalStatus" : [ ]
  } ],
  "subpathways" : [ {
    "dbId" : 10650670,
    "stId" : "R-DRE-9839389",
    "displayName" : "TGFBR3 regulates TGF-beta signaling",
    "events" : [ 10643574, 10643578, 10643563, 10643592, 10643566, 10643599, 10643580, 10643596 ]
  }, {
    "dbId" : 10650674,
    "stId" : "R-DRE-9839383",
    "displayName" : "TGFBR3 PTM regulation",
    "events" : [ 10643570, 10643590, 10643576 ]
  }, {
    "dbId" : 10650676,
    "stId" : "R-DRE-9839397",
    "displayName" : "TGFBR3 regulates FGF2 signaling",
    "events" : [ 10643584, 10643582 ]
  }, {
    "dbId" : 10650678,
    "stId" : "R-DRE-9839406",
    "displayName" : "TGFBR3 regulates activin signaling",
    "events" : [ 10643586, 10643601 ]
  } ]
}