{
  "dbId" : 10650290,
  "stId" : "R-DRE-8856825",
  "speciesName" : "Danio rerio",
  "nodes" : [ {
    "dbId" : 10609825,
    "stId" : "R-DRE-182197",
    "displayName" : "ap2s1 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 68323,
    "identifier" : "Q6PEJ2",
    "standardIdentifier" : "uniprot:Q6PEJ2",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "ap2s1" ],
    "parents" : [ 10609827 ],
    "children" : [ ]
  }, {
    "dbId" : 10609827,
    "stId" : "R-DRE-167712",
    "displayName" : "AP-2 Complex [cytosol]",
    "schemaClass" : "Complex",
    "speciesId" : 68323,
    "diagramIds" : [ 30443 ],
    "parents" : [ 10631528, 10631530 ],
    "children" : [ 10609823, 10609817, 10609815, 10609825 ]
  }, {
    "dbId" : 10631072,
    "stId" : "R-DRE-416964",
    "displayName" : "cops7a [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 68323,
    "identifier" : "F6PBL6",
    "standardIdentifier" : "uniprot:F6PBL6",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "cops7a" ],
    "parents" : [ 10631076 ],
    "children" : [ ]
  }, {
    "dbId" : 10631078,
    "stId" : "R-DRE-8863731",
    "displayName" : "NEDD8-STONs:TOR1 hexamer:COP9 [cytosol]",
    "schemaClass" : "Complex",
    "speciesId" : 68323,
    "diagramIds" : [ 30435 ],
    "parents" : [ ],
    "children" : [ 10631076, 10631030, 10631056 ]
  }, {
    "dbId" : 10631076,
    "stId" : "R-DRE-416968",
    "displayName" : "COP9 [cytosol]",
    "schemaClass" : "Complex",
    "speciesId" : 68323,
    "diagramIds" : [ 30433 ],
    "parents" : [ 10631078 ],
    "children" : [ 10631068, 10631070, 10631064, 10631066, 10631060, 10631062, 10631072, 10631058 ]
  }, {
    "dbId" : 10583979,
    "stId" : "R-DRE-264470",
    "displayName" : "arrb1 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 68323,
    "identifier" : "C3PTE8",
    "standardIdentifier" : "uniprot:C3PTE8",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "arrb1" ],
    "parents" : [ 10614041 ],
    "children" : [ ]
  }, {
    "dbId" : 10590128,
    "stId" : "R-DRE-917983",
    "displayName" : "tfr1a [plasma membrane]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 68323,
    "identifier" : "Q5MPX4",
    "standardIdentifier" : "uniprot:Q5MPX4",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "tfr1a" ],
    "parents" : [ 10590130 ],
    "children" : [ ]
  }, {
    "dbId" : 10590130,
    "stId" : "R-DRE-917784",
    "displayName" : "TFRC dimer [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 68323,
    "parents" : [ 10590134 ],
    "children" : [ 10590128 ]
  }, {
    "dbId" : 10590132,
    "stId" : "R-DRE-917889",
    "displayName" : "holoTF [extracellular region]",
    "schemaClass" : "Complex",
    "speciesId" : 68323,
    "parents" : [ 10590134 ],
    "children" : [ 912516, 10588178 ]
  }, {
    "dbId" : 10650292,
    "stId" : "R-DRE-8856828",
    "displayName" : "Clathrin-mediated endocytosis",
    "schemaClass" : "Pathway",
    "speciesId" : 68323,
    "diagramIds" : [ 30462 ]
  }, {
    "dbId" : 10590134,
    "stId" : "R-DRE-917834",
    "displayName" : "holoTF:TFRC dimer [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 68323,
    "parents" : [ 10631510 ],
    "children" : [ 10590132, 10590130 ]
  }, {
    "dbId" : 10579902,
    "stId" : "R-DRE-376361",
    "displayName" : "sybl1 [plasma membrane]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 68323,
    "diagramIds" : [ 30438 ],
    "identifier" : "E9QC42",
    "standardIdentifier" : "uniprot:E9QC42",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "sybl1" ],
    "parents" : [ 10631020 ],
    "children" : [ ]
  }, {
    "dbId" : 10631042,
    "stId" : "R-DRE-8862858-3",
    "displayName" : "TOR1A [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 68323,
    "identifier" : "E9QG29",
    "standardIdentifier" : "uniprot:E9QG29",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 10631048 ],
    "children" : [ ]
  }, {
    "dbId" : 10631046,
    "stId" : "R-DRE-8862858-4",
    "displayName" : "TOR1A [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 68323,
    "identifier" : "Q6P5L4",
    "standardIdentifier" : "uniprot:Q6P5L4",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 10631048 ],
    "children" : [ ]
  }, {
    "dbId" : 10609796,
    "stId" : "R-DRE-443956",
    "displayName" : "Ghost homologue of FZD4 [plasma membrane]",
    "schemaClass" : "GenomeEncodedEntity",
    "speciesId" : 68323,
    "parents" : [ 10609798 ],
    "children" : [ ]
  }, {
    "dbId" : 10609798,
    "stId" : "R-DRE-5099901",
    "displayName" : "N4GlycoAsn-PalmS-WNT5A:FZD4 [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 68323,
    "parents" : [ 10609802 ],
    "children" : [ 10609796, 10607683 ]
  }, {
    "dbId" : 10631050,
    "stId" : "R-DRE-8862868",
    "displayName" : "TOR1A hexamer [cytosol]",
    "schemaClass" : "Complex",
    "speciesId" : 68323,
    "parents" : [ 10631056 ],
    "children" : [ 10631048 ]
  }, {
    "dbId" : 10623371,
    "stId" : "R-DRE-6806532",
    "displayName" : "igf2r [plasma membrane]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 68323,
    "identifier" : "Q2TTK0",
    "standardIdentifier" : "uniprot:Q2TTK0",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "igf2r" ],
    "parents" : [ 10631510 ],
    "children" : [ ]
  }, {
    "dbId" : 10631048,
    "stId" : "R-DRE-8862858-5",
    "displayName" : "Homologues of TOR1A [cytosol]",
    "schemaClass" : "DefinedSet",
    "speciesId" : 68323,
    "parents" : [ 10631050 ],
    "children" : [ 10631038, 10631034, 10631046, 10631042 ]
  }, {
    "dbId" : 10609802,
    "stId" : "R-DRE-5138442",
    "displayName" : "WNT5A:FZD4:p-DVL2 [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 68323,
    "parents" : [ 10631496 ],
    "children" : [ 10575963, 10609798 ]
  }, {
    "dbId" : 10631054,
    "stId" : "R-DRE-8862866",
    "displayName" : "TOR1B hexamer [cytosol]",
    "schemaClass" : "Complex",
    "speciesId" : 68323,
    "parents" : [ 10631056 ],
    "children" : [ 10631052 ]
  }, {
    "dbId" : 10589324,
    "stId" : "R-DRE-168786",
    "displayName" : "syt1a [plasma membrane]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 68323,
    "identifier" : "Q5TZ27",
    "standardIdentifier" : "uniprot:Q5TZ27",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "syt1a" ],
    "parents" : [ 10630952 ],
    "children" : [ ]
  }, {
    "dbId" : 10631052,
    "stId" : "R-DRE-8862861",
    "displayName" : "TOR1B [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 68323,
    "identifier" : "E9QG29",
    "standardIdentifier" : "uniprot:E9QG29",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 10631054 ],
    "children" : [ ]
  }, {
    "dbId" : 10580878,
    "stId" : "R-DRE-390654",
    "displayName" : "chrm2a [plasma membrane]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 68323,
    "identifier" : "B3DKN8",
    "standardIdentifier" : "uniprot:B3DKN8",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "chrm2a" ],
    "parents" : [ 10631496 ],
    "children" : [ ]
  }, {
    "dbId" : 10631058,
    "stId" : "R-DRE-416972",
    "displayName" : "Ghost homologue of GPS1 [cytosol]",
    "schemaClass" : "GenomeEncodedEntity",
    "speciesId" : 68323,
    "parents" : [ 10631076 ],
    "children" : [ ]
  }, {
    "dbId" : 10631056,
    "stId" : "R-DRE-8863573",
    "displayName" : "TOR1 hexamer [cytosol]",
    "schemaClass" : "CandidateSet",
    "speciesId" : 68323,
    "diagramIds" : [ 30434 ],
    "parents" : [ 10631078 ],
    "children" : [ 10631050, 10631054 ]
  }, {
    "dbId" : 10631062,
    "stId" : "R-DRE-416973",
    "displayName" : "cops3 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 68323,
    "identifier" : "Q6P2U9",
    "standardIdentifier" : "uniprot:Q6P2U9",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "cops3" ],
    "parents" : [ 10631076 ],
    "children" : [ ]
  }, {
    "dbId" : 10609815,
    "stId" : "R-DRE-182144",
    "displayName" : "Ghost homologue of Adaptor protein complex 2 (AP-2) large adaptins [cytosol]",
    "schemaClass" : "GenomeEncodedEntity",
    "speciesId" : 68323,
    "parents" : [ 10609827 ],
    "children" : [ ]
  }, {
    "dbId" : 10631060,
    "stId" : "R-DRE-416971",
    "displayName" : "cops2 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 68323,
    "identifier" : "Q6IQT4",
    "standardIdentifier" : "uniprot:Q6IQT4",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "cops2" ],
    "parents" : [ 10631076 ],
    "children" : [ ]
  }, {
    "dbId" : 10609817,
    "stId" : "R-DRE-182166",
    "displayName" : "ap2b1 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 68323,
    "identifier" : "Q6NYJ9",
    "standardIdentifier" : "uniprot:Q6NYJ9",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "ap2b1" ],
    "parents" : [ 10609827 ],
    "children" : [ ]
  }, {
    "dbId" : 10631066,
    "stId" : "R-DRE-416963",
    "displayName" : "COPS5 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 68323,
    "identifier" : "Q6PC30",
    "standardIdentifier" : "uniprot:Q6PC30",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 10631076 ],
    "children" : [ ]
  }, {
    "dbId" : 10609819,
    "stId" : "R-DRE-182227",
    "displayName" : "AP2M1 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 68323,
    "identifier" : "Q6NWK2",
    "standardIdentifier" : "uniprot:Q6NWK2",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 10609823 ],
    "children" : [ ]
  }, {
    "dbId" : 10631064,
    "stId" : "R-DRE-416965",
    "displayName" : "cops4 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 68323,
    "identifier" : "Q6P0H6",
    "standardIdentifier" : "uniprot:Q6P0H6",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "cops4" ],
    "parents" : [ 10631076 ],
    "children" : [ ]
  }, {
    "dbId" : 10609821,
    "stId" : "R-DRE-182227-2",
    "displayName" : "AP2M1 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 68323,
    "identifier" : "Q7ZW98",
    "standardIdentifier" : "uniprot:Q7ZW98",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 10609823 ],
    "children" : [ ]
  }, {
    "dbId" : 10631070,
    "stId" : "R-DRE-416962",
    "displayName" : "cops8 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 68323,
    "identifier" : "Q7ZUZ0",
    "standardIdentifier" : "uniprot:Q7ZUZ0",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "cops8" ],
    "parents" : [ 10631076 ],
    "children" : [ ]
  }, {
    "dbId" : 10609823,
    "stId" : "R-DRE-182227-3",
    "displayName" : "Homologues of AP2M1 [cytosol]",
    "schemaClass" : "DefinedSet",
    "speciesId" : 68323,
    "parents" : [ 10609827 ],
    "children" : [ 10609821, 10609819 ]
  }, {
    "dbId" : 10631068,
    "stId" : "R-DRE-416961",
    "displayName" : "Ghost homologue of COPS6 [cytosol]",
    "schemaClass" : "GenomeEncodedEntity",
    "speciesId" : 68323,
    "parents" : [ 10631076 ],
    "children" : [ ]
  }, {
    "dbId" : 9648300,
    "stId" : "R-ALL-9648300",
    "displayName" : "chlorpromazine [cytosol]",
    "schemaClass" : "ChemicalDrug",
    "speciesId" : 0,
    "diagramIds" : [ 30457 ],
    "identifier" : "83",
    "standardIdentifier" : "iuphar.ligand:83",
    "chebiIdentifier" : "chebi:3647",
    "parents" : [ 10631530 ],
    "children" : [ ]
  }, {
    "dbId" : 10579428,
    "stId" : "R-DRE-374247",
    "displayName" : "agtr1b [plasma membrane]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 68323,
    "identifier" : "E7FEQ8",
    "standardIdentifier" : "uniprot:E7FEQ8",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "agtr1b" ],
    "parents" : [ 10631496 ],
    "children" : [ ]
  }, {
    "dbId" : 10584002,
    "stId" : "R-DRE-416464",
    "displayName" : "arrb2a [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 68323,
    "identifier" : "A0A286YBG8",
    "standardIdentifier" : "uniprot:A0A286YBG8",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "arrb2a" ],
    "parents" : [ 10614041 ],
    "children" : [ ]
  }, {
    "dbId" : 10585293,
    "stId" : "R-DRE-429140",
    "displayName" : "slc2a8 [plasma membrane]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 68323,
    "identifier" : "Q7ZWH3",
    "standardIdentifier" : "uniprot:Q7ZWH3",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "slc2a8" ],
    "parents" : [ 10631524 ],
    "children" : [ ]
  }, {
    "dbId" : 10630179,
    "stId" : "R-DRE-8852152",
    "displayName" : "pS-ADRB2:Catecholamine [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 68323,
    "parents" : [ 10631496 ],
    "children" : [ 10629916, 390627 ]
  }, {
    "dbId" : 10580515,
    "stId" : "R-DRE-380103",
    "displayName" : "tacr1a [plasma membrane]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 68323,
    "identifier" : "E9QCW0",
    "standardIdentifier" : "uniprot:E9QCW0",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "tacr1a" ],
    "parents" : [ 10631496 ],
    "children" : [ ]
  }, {
    "dbId" : 912516,
    "stId" : "R-ALL-912516",
    "displayName" : "Fe3+ [extracellular region]",
    "schemaClass" : "SimpleEntity",
    "speciesId" : 0,
    "identifier" : "29034",
    "standardIdentifier" : "chebi:29034",
    "referenceType" : "ReferenceMolecule",
    "parents" : [ 10590132 ],
    "children" : [ ]
  }, {
    "dbId" : 10630952,
    "stId" : "R-DRE-8862877",
    "displayName" : "SYT1 dimer [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 68323,
    "parents" : [ 10630972 ],
    "children" : [ 10589324 ]
  }, {
    "dbId" : 10630958,
    "stId" : "R-DRE-8862876",
    "displayName" : "SYT2 dimer [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 68323,
    "parents" : [ 10630972 ],
    "children" : [ 10630956 ]
  }, {
    "dbId" : 10630956,
    "stId" : "R-DRE-168795",
    "displayName" : "syt2a [plasma membrane]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 68323,
    "identifier" : "F1R5C0",
    "standardIdentifier" : "uniprot:F1R5C0",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "syt2a" ],
    "parents" : [ 10630958 ],
    "children" : [ ]
  }, {
    "dbId" : 549254,
    "stId" : "R-ALL-549254",
    "displayName" : "ADR [extracellular region]",
    "schemaClass" : "SimpleEntity",
    "speciesId" : 0,
    "identifier" : "71406",
    "standardIdentifier" : "chebi:71406",
    "referenceType" : "ReferenceMolecule",
    "parents" : [ 390627 ],
    "children" : [ ]
  }, {
    "dbId" : 10630962,
    "stId" : "R-DRE-5216191",
    "displayName" : "syt9b [plasma membrane]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 68323,
    "identifier" : "Q68EH6",
    "standardIdentifier" : "uniprot:Q68EH6",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "syt9b" ],
    "parents" : [ 10630964 ],
    "children" : [ ]
  }, {
    "dbId" : 374935,
    "stId" : "R-ALL-374935",
    "displayName" : "NAd [extracellular region]",
    "schemaClass" : "SimpleEntity",
    "speciesId" : 0,
    "identifier" : "72587",
    "standardIdentifier" : "chebi:72587",
    "referenceType" : "ReferenceMolecule",
    "parents" : [ 390627 ],
    "children" : [ ]
  }, {
    "dbId" : 10630964,
    "stId" : "R-DRE-8862869",
    "displayName" : "SYT9 dimer [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 68323,
    "parents" : [ 10630972 ],
    "children" : [ 10630962 ]
  }, {
    "dbId" : 10630970,
    "stId" : "R-DRE-8862874",
    "displayName" : "SYT11 dimer [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 68323,
    "parents" : [ 10630972 ],
    "children" : [ 10630968 ]
  }, {
    "dbId" : 10631483,
    "stId" : "R-DRE-8866009",
    "displayName" : "phospho-avpr2l [plasma membrane]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 68323,
    "identifier" : "A8KB27",
    "standardIdentifier" : "uniprot:A8KB27",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "avpr2l" ],
    "parents" : [ 10631485 ],
    "children" : [ ]
  }, {
    "dbId" : 10630968,
    "stId" : "R-DRE-5216001",
    "displayName" : "syt11a [plasma membrane]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 68323,
    "identifier" : "F1RD06",
    "standardIdentifier" : "uniprot:F1RD06",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "syt11a" ],
    "parents" : [ 10630970 ],
    "children" : [ ]
  }, {
    "dbId" : 10631487,
    "stId" : "R-DRE-8866004",
    "displayName" : "ADRBK2 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 68323,
    "identifier" : "A0A2R8QPB8",
    "standardIdentifier" : "uniprot:A0A2R8QPB8",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 10631491 ],
    "children" : [ ]
  }, {
    "dbId" : 10630972,
    "stId" : "R-DRE-8862881",
    "displayName" : "SYT dimers [plasma membrane]",
    "schemaClass" : "CandidateSet",
    "speciesId" : 68323,
    "diagramIds" : [ 30427 ],
    "parents" : [ 10630984 ],
    "children" : [ 10630958, 10630952, 10630964, 10630970 ]
  }, {
    "dbId" : 10631485,
    "stId" : "R-DRE-8866248",
    "displayName" : "p-AVPR2:AVP(20-28) [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 68323,
    "diagramIds" : [ 30454 ],
    "parents" : [ 10631496 ],
    "children" : [ 10580301, 10631483 ]
  }, {
    "dbId" : 10588178,
    "stId" : "R-DRE-350754",
    "displayName" : "apoTF [extracellular region]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 68323,
    "identifier" : "B8JL43",
    "standardIdentifier" : "uniprot:B8JL43",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 10590132 ],
    "children" : [ ]
  }, {
    "dbId" : 10614041,
    "stId" : "R-DRE-1911410",
    "displayName" : "ARRB [cytosol]",
    "schemaClass" : "DefinedSet",
    "speciesId" : 68323,
    "diagramIds" : [ 30448 ],
    "parents" : [ 10631498 ],
    "children" : [ 10583979, 10584002 ]
  }, {
    "dbId" : 113592,
    "stId" : "R-ALL-113592",
    "displayName" : "ATP [cytosol]",
    "schemaClass" : "SimpleEntity",
    "speciesId" : 0,
    "diagramIds" : [ 30452 ],
    "identifier" : "30616",
    "standardIdentifier" : "chebi:30616",
    "referenceType" : "ReferenceMolecule",
    "parents" : [ ],
    "children" : [ ]
  }, {
    "dbId" : 29370,
    "stId" : "R-ALL-29370",
    "displayName" : "ADP [cytosol]",
    "schemaClass" : "SimpleEntity",
    "speciesId" : 0,
    "diagramIds" : [ 30453 ],
    "identifier" : "456216",
    "standardIdentifier" : "chebi:456216",
    "referenceType" : "ReferenceMolecule",
    "parents" : [ ],
    "children" : [ ]
  }, {
    "dbId" : 10629916,
    "stId" : "R-DRE-8852158",
    "displayName" : "phospho-adrb2a [plasma membrane]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 68323,
    "identifier" : "I7GPU6",
    "standardIdentifier" : "uniprot:I7GPU6",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "adrb2a" ],
    "parents" : [ 10630179 ],
    "children" : [ ]
  }, {
    "dbId" : 10631522,
    "stId" : "R-DRE-8864566-3",
    "displayName" : "Homologues of SCARB2 [plasma membrane]",
    "schemaClass" : "DefinedSet",
    "speciesId" : 68323,
    "parents" : [ 10631524 ],
    "children" : [ 10631516, 10631520 ]
  }, {
    "dbId" : 10631520,
    "stId" : "R-DRE-8864566-2",
    "displayName" : "scarb2a [plasma membrane]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 68323,
    "identifier" : "Q8JGR8",
    "standardIdentifier" : "uniprot:Q8JGR8",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "scarb2a" ],
    "parents" : [ 10631522 ],
    "children" : [ ]
  }, {
    "dbId" : 10631526,
    "stId" : "R-DRE-8866235",
    "displayName" : "AP-2 cargo [plasma membrane]",
    "schemaClass" : "DefinedSet",
    "speciesId" : 68323,
    "diagramIds" : [ 30442 ],
    "parents" : [ 10631528 ],
    "children" : [ 10631524, 10631510 ]
  }, {
    "dbId" : 10631524,
    "stId" : "R-DRE-8866234",
    "displayName" : "AP-2 dileucine-containing cargo [plasma membrane]",
    "schemaClass" : "DefinedSet",
    "speciesId" : 68323,
    "parents" : [ 10631526 ],
    "children" : [ 10585293, 10631512, 10586966, 10631522 ]
  }, {
    "dbId" : 10631530,
    "stId" : "R-DRE-9681612",
    "displayName" : "AP2:chlorpromazine [cytosol]",
    "schemaClass" : "Complex",
    "speciesId" : 68323,
    "diagramIds" : [ 30445 ],
    "parents" : [ ],
    "children" : [ 9648300, 10609827 ]
  }, {
    "dbId" : 10631018,
    "stId" : "R-DRE-8863714",
    "displayName" : "agfg1b [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 68323,
    "diagramIds" : [ 30439 ],
    "identifier" : "B0UXL9",
    "standardIdentifier" : "uniprot:B0UXL9",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "agfg1b" ],
    "parents" : [ 10631020 ],
    "children" : [ ]
  }, {
    "dbId" : 10631528,
    "stId" : "R-DRE-8866238",
    "displayName" : "AP-2:cargo [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 68323,
    "diagramIds" : [ 30444 ],
    "parents" : [ ],
    "children" : [ 10631526, 10609827 ]
  }, {
    "dbId" : 10631020,
    "stId" : "R-DRE-8863716",
    "displayName" : "AGFG1:VAMP7 [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 68323,
    "diagramIds" : [ 30440 ],
    "parents" : [ ],
    "children" : [ 10579902, 10631018 ]
  }, {
    "dbId" : 10631025,
    "stId" : "R-DRE-8863733",
    "displayName" : "ston2 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 68323,
    "identifier" : "Q4V9G6",
    "standardIdentifier" : "uniprot:Q4V9G6",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "ston2" ],
    "parents" : [ 10631030 ],
    "children" : [ ]
  }, {
    "dbId" : 10631030,
    "stId" : "R-DRE-8863725",
    "displayName" : "NEDD8-STONs [cytosol]",
    "schemaClass" : "CandidateSet",
    "speciesId" : 68323,
    "diagramIds" : [ 30431 ],
    "parents" : [ 10631078 ],
    "children" : [ 10631025, 10631028 ]
  }, {
    "dbId" : 10631028,
    "stId" : "R-DRE-8863726",
    "displayName" : "ston1 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 68323,
    "identifier" : "F1R8F7",
    "standardIdentifier" : "uniprot:F1R8F7",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "ston1" ],
    "parents" : [ 10631030 ],
    "children" : [ ]
  }, {
    "dbId" : 10631034,
    "stId" : "R-DRE-8862858",
    "displayName" : "TOR1A [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 68323,
    "identifier" : "B3DJX5",
    "standardIdentifier" : "uniprot:B3DJX5",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 10631048 ],
    "children" : [ ]
  }, {
    "dbId" : 10631038,
    "stId" : "R-DRE-8862858-2",
    "displayName" : "TOR1A [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 68323,
    "identifier" : "E7FDJ9",
    "standardIdentifier" : "uniprot:E7FDJ9",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 10631048 ],
    "children" : [ ]
  }, {
    "dbId" : 10631491,
    "stId" : "R-DRE-8866229",
    "displayName" : "ADBRK1,2 [cytosol]",
    "schemaClass" : "DefinedSet",
    "speciesId" : 68323,
    "diagramIds" : [ 30455 ],
    "parents" : [ ],
    "children" : [ 10631487, 10631489 ]
  }, {
    "dbId" : 10630976,
    "stId" : "R-DRE-8862856",
    "displayName" : "ston2 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 68323,
    "identifier" : "Q4V9G6",
    "standardIdentifier" : "uniprot:Q4V9G6",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "ston2" ],
    "parents" : [ 10630982 ],
    "children" : [ ]
  }, {
    "dbId" : 10607683,
    "stId" : "R-DRE-3781973",
    "displayName" : "wnt5a [extracellular exosome]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 68323,
    "identifier" : "A1BPR0",
    "standardIdentifier" : "uniprot:A1BPR0",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "wnt5a" ],
    "parents" : [ 10609798 ],
    "children" : [ ]
  }, {
    "dbId" : 10631489,
    "stId" : "R-DRE-9645318",
    "displayName" : "phospho-p-S29-ADRBK1 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 68323,
    "identifier" : "A0A2R8QPB8",
    "standardIdentifier" : "uniprot:A0A2R8QPB8",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 10631491 ],
    "children" : [ ]
  }, {
    "dbId" : 10630982,
    "stId" : "R-DRE-8862880",
    "displayName" : "STON2,1 [cytosol]",
    "schemaClass" : "CandidateSet",
    "speciesId" : 68323,
    "diagramIds" : [ 30426 ],
    "parents" : [ 10630984 ],
    "children" : [ 10630976, 10630980 ]
  }, {
    "dbId" : 10580295,
    "stId" : "R-DRE-388474",
    "displayName" : "avp [extracellular region]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 68323,
    "identifier" : "Q8AV79",
    "standardIdentifier" : "uniprot:Q8AV79",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "avp" ],
    "parents" : [ 10580301 ],
    "children" : [ ]
  }, {
    "dbId" : 10630980,
    "stId" : "R-DRE-8862854",
    "displayName" : "ston1 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 68323,
    "identifier" : "F1R8F7",
    "standardIdentifier" : "uniprot:F1R8F7",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "ston1" ],
    "parents" : [ 10630982 ],
    "children" : [ ]
  }, {
    "dbId" : 390627,
    "stId" : "R-ALL-390627",
    "displayName" : "ADR, NAd [extracellular region]",
    "schemaClass" : "DefinedSet",
    "speciesId" : 0,
    "parents" : [ 10630179 ],
    "children" : [ 374935, 549254 ]
  }, {
    "dbId" : 10631498,
    "stId" : "R-DRE-8866263",
    "displayName" : "ARRB:ARRB-binding GPCRs [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 68323,
    "diagramIds" : [ 30449 ],
    "parents" : [ ],
    "children" : [ 10631496, 10614041 ]
  }, {
    "dbId" : 10580299,
    "stId" : "R-DRE-388474-2",
    "displayName" : "oxt [extracellular region]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 68323,
    "identifier" : "Q8UUT8",
    "standardIdentifier" : "uniprot:Q8UUT8",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "oxt" ],
    "parents" : [ 10580301 ],
    "children" : [ ]
  }, {
    "dbId" : 10630984,
    "stId" : "R-DRE-8862879",
    "displayName" : "STON2,1:SYT dimers [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 68323,
    "diagramIds" : [ 30428 ],
    "parents" : [ ],
    "children" : [ 10630972, 10630982 ]
  }, {
    "dbId" : 10631496,
    "stId" : "R-DRE-8866250",
    "displayName" : "ARRB-binding GPCRs [plasma membrane]",
    "schemaClass" : "CandidateSet",
    "speciesId" : 68323,
    "diagramIds" : [ 30447 ],
    "parents" : [ 10631498 ],
    "children" : [ 10631485, 10580878, 10609802, 10630179, 10579428, 10580515 ]
  }, {
    "dbId" : 10580301,
    "stId" : "R-DRE-388474-3",
    "displayName" : "Homologues of AVP(20-28) [extracellular region]",
    "schemaClass" : "DefinedSet",
    "speciesId" : 68323,
    "parents" : [ 10631485, 10583378 ],
    "children" : [ 10580299, 10580295 ]
  }, {
    "dbId" : 10631502,
    "stId" : "R-DRE-372513",
    "displayName" : "slc18a3a [plasma membrane]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 68323,
    "identifier" : "Q08C75",
    "standardIdentifier" : "uniprot:Q08C75",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "slc18a3a" ],
    "parents" : [ 10631510 ],
    "children" : [ ]
  }, {
    "dbId" : 10618959,
    "stId" : "R-DRE-5690794",
    "displayName" : "nedd8 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 68323,
    "identifier" : "F1QMF9",
    "standardIdentifier" : "uniprot:F1QMF9",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "nedd8" ],
    "parents" : [ 10618963 ],
    "children" : [ ]
  }, {
    "dbId" : 10630988,
    "stId" : "R-DRE-8862456",
    "displayName" : "dab2 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 68323,
    "diagramIds" : [ 30422 ],
    "identifier" : "A0A8M1P9G4",
    "standardIdentifier" : "uniprot:A0A8M1P9G4",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "dab2" ],
    "parents" : [ 10630994 ],
    "children" : [ ]
  }, {
    "dbId" : 10630994,
    "stId" : "R-DRE-8862884",
    "displayName" : "LRP2:DAB2 [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 68323,
    "diagramIds" : [ 30424 ],
    "parents" : [ ],
    "children" : [ 10630988, 10630992 ]
  }, {
    "dbId" : 10631506,
    "stId" : "R-DRE-8867595",
    "displayName" : "PolyUb-CFTR [plasma membrane]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 68323,
    "identifier" : "Q1LX78",
    "standardIdentifier" : "uniprot:Q1LX78",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 10631510 ],
    "children" : [ ]
  }, {
    "dbId" : 10583376,
    "stId" : "R-DRE-388431",
    "displayName" : "avpr2l [plasma membrane]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 68323,
    "identifier" : "A8KB27",
    "standardIdentifier" : "uniprot:A8KB27",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "avpr2l" ],
    "parents" : [ 10583378 ],
    "children" : [ ]
  }, {
    "dbId" : 10618963,
    "stId" : "R-DRE-5690794-3",
    "displayName" : "Homologues of NEDD8(1-81) [cytosol]",
    "schemaClass" : "DefinedSet",
    "speciesId" : 68323,
    "diagramIds" : [ 30430 ],
    "parents" : [ ],
    "children" : [ 10618959, 10618961 ]
  }, {
    "dbId" : 10630992,
    "stId" : "R-DRE-350083",
    "displayName" : "lrp2a [plasma membrane]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 68323,
    "diagramIds" : [ 30423 ],
    "identifier" : "E0AE56",
    "standardIdentifier" : "uniprot:E0AE56",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "lrp2a" ],
    "parents" : [ 10630994 ],
    "children" : [ ]
  }, {
    "dbId" : 10631504,
    "stId" : "R-DRE-8864564",
    "displayName" : "m6pr [plasma membrane]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 68323,
    "identifier" : "Q6P032",
    "standardIdentifier" : "uniprot:Q6P032",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "m6pr" ],
    "parents" : [ 10631510 ],
    "children" : [ ]
  }, {
    "dbId" : 10583378,
    "stId" : "R-DRE-392261",
    "displayName" : "AVPR2:AVP(20-28) [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 68323,
    "diagramIds" : [ 30451 ],
    "parents" : [ ],
    "children" : [ 10580301, 10583376 ]
  }, {
    "dbId" : 10618961,
    "stId" : "R-DRE-5690794-2",
    "displayName" : "nedd8l [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 68323,
    "identifier" : "Q6DGU4",
    "standardIdentifier" : "uniprot:Q6DGU4",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "nedd8l" ],
    "parents" : [ 10618963 ],
    "children" : [ ]
  }, {
    "dbId" : 10631510,
    "stId" : "R-DRE-8866232",
    "displayName" : "AP-2 YXXPhi cargo [plasma membrane]",
    "schemaClass" : "DefinedSet",
    "speciesId" : 68323,
    "parents" : [ 10631526 ],
    "children" : [ 10631502, 10623371, 10590134, 10631508, 10631504, 10631506 ]
  }, {
    "dbId" : 10631508,
    "stId" : "R-DRE-449945",
    "displayName" : "il7r [plasma membrane]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 68323,
    "identifier" : "E9QDP8",
    "standardIdentifier" : "uniprot:E9QDP8",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "il7r" ],
    "parents" : [ 10631510 ],
    "children" : [ ]
  }, {
    "dbId" : 10586966,
    "stId" : "R-DRE-167542",
    "displayName" : "cd4-1 [plasma membrane]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 68323,
    "identifier" : "B5KH12",
    "standardIdentifier" : "uniprot:B5KH12",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "cd4-1" ],
    "parents" : [ 10631524 ],
    "children" : [ ]
  }, {
    "dbId" : 10631512,
    "stId" : "R-DRE-8864461",
    "displayName" : "vamp4 [plasma membrane]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 68323,
    "identifier" : "F6P4N7",
    "standardIdentifier" : "uniprot:F6P4N7",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "vamp4" ],
    "parents" : [ 10631524 ],
    "children" : [ ]
  }, {
    "dbId" : 10575963,
    "stId" : "R-DRE-201706",
    "displayName" : "phospho-dvl2 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 68323,
    "identifier" : "Q803Q5",
    "standardIdentifier" : "uniprot:Q803Q5",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "dvl2" ],
    "parents" : [ 10609802 ],
    "children" : [ ]
  }, {
    "dbId" : 10631516,
    "stId" : "R-DRE-8864566",
    "displayName" : "scarb2b [plasma membrane]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 68323,
    "identifier" : "A0A2R8Q7M1",
    "standardIdentifier" : "uniprot:A0A2R8Q7M1",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "scarb2b" ],
    "parents" : [ 10631522 ],
    "children" : [ ]
  } ],
  "edges" : [ {
    "dbId" : 10631494,
    "stId" : "R-DRE-8866268",
    "displayName" : "ADBRK1,2 phosphorylate AVPR2",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "inputs" : [ 113592, 10583378 ],
    "outputs" : [ 10631485, 29370 ],
    "catalysts" : [ 10631491 ],
    "efs" : [ ],
    "diagramIds" : [ 30450 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10630996,
    "stId" : "R-DRE-8863472",
    "displayName" : "DAB2 binds LRP2",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "inputs" : [ 10630988, 10630992 ],
    "outputs" : [ 10630994 ],
    "efs" : [ ],
    "diagramIds" : [ 30421 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10640250,
    "stId" : "R-DRE-9681616",
    "displayName" : "AP2 binds chlorpromazine",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "inputs" : [ 9648300, 10609827 ],
    "outputs" : [ 10631530 ],
    "efs" : [ ],
    "diagramIds" : [ 30456 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10630986,
    "stId" : "R-DRE-8863463",
    "displayName" : "STON2 binds SYT proteins",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "inputs" : [ 10630972, 10630982 ],
    "outputs" : [ 10630984 ],
    "efs" : [ ],
    "diagramIds" : [ 30425 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10631083,
    "stId" : "R-DRE-8863723",
    "displayName" : "COP9 and TOR1 deneddylate STON2",
    "schemaClass" : "BlackBoxEvent",
    "speciesId" : 0,
    "preceding" : [ 10631080 ],
    "inputs" : [ 10631078 ],
    "outputs" : [ 10631076, 10630982, 10631056, 10618963 ],
    "catalysts" : [ 10631078 ],
    "efs" : [ ],
    "diagramIds" : [ 30436 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10631080,
    "stId" : "R-DRE-8863721",
    "displayName" : "NEDD8-STON binds TOR1 hexamer and COP9 complex",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "preceding" : [ 10631085 ],
    "following" : [ 10631083 ],
    "inputs" : [ 10631076, 10631030, 10631056 ],
    "outputs" : [ 10631078 ],
    "efs" : [ ],
    "diagramIds" : [ 30432 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10631022,
    "stId" : "R-DRE-8863718",
    "displayName" : "AGFG1 binds VAMP7",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "inputs" : [ 10579902, 10631018 ],
    "outputs" : [ 10631020 ],
    "efs" : [ ],
    "diagramIds" : [ 30437 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10631532,
    "stId" : "R-DRE-8866277",
    "displayName" : "AP-2 directly binds some endocytic cargo",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "inputs" : [ 10631526, 10609827 ],
    "outputs" : [ 10631528 ],
    "efs" : [ ],
    "inhibitors" : [ 10631530 ],
    "diagramIds" : [ 30441 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10631500,
    "stId" : "R-DRE-8866269",
    "displayName" : "ARRB bind GPCRs",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "inputs" : [ 10631496, 10614041 ],
    "outputs" : [ 10631498 ],
    "efs" : [ ],
    "diagramIds" : [ 30446 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10631085,
    "stId" : "R-DRE-8863727",
    "displayName" : "STON2 is neddylated",
    "schemaClass" : "BlackBoxEvent",
    "speciesId" : 0,
    "following" : [ 10631080 ],
    "inputs" : [ 10630982, 10618963 ],
    "outputs" : [ 10631030 ],
    "efs" : [ ],
    "diagramIds" : [ 30429 ],
    "entityFunctionalStatus" : [ ]
  } ]
}