{ "dbId" : 10649048, "stableId" : "R-DRE-5576891", "displayName" : "Cardiac conduction", "nodes" : [ { "id" : 86145, "reactomeId" : 74126, "displayName" : "K+", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 62, "y" : 400 }, "minX" : 44, "maxX" : 148, "minY" : 384, "maxY" : 415, "prop" : { "x" : 44, "y" : 385, "width" : 36, "height" : 30 }, "textPosition" : { "x" : 49, "y" : 389 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 75, "y" : 390 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 75, "y" : 390 } } }, "connectors" : [ { "edgeId" : 86141, "type" : "INPUT", "segments" : [ { "from" : { "x" : 83, "y" : 402 }, "to" : { "x" : 148, "y" : 410 } } ], "stoichiometry" : { "value" : 2, "shape" : { "a" : { "x" : 109, "y" : 400 }, "b" : { "x" : 121, "y" : 412 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 115, "y" : 406 } } } } ] }, { "id" : 86144, "reactomeId" : 83910, "displayName" : "Na+", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 275, "y" : 411 }, "minX" : 148, "maxX" : 297, "minY" : 395, "maxY" : 426, "prop" : { "x" : 254, "y" : 396, "width" : 42, "height" : 30 }, "textPosition" : { "x" : 257, "y" : 400 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 291, "y" : 401 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 291, "y" : 401 } } }, "connectors" : [ { "edgeId" : 86141, "type" : "INPUT", "segments" : [ { "from" : { "x" : 251, "y" : 410 }, "to" : { "x" : 148, "y" : 410 } } ], "stoichiometry" : { "value" : 3, "shape" : { "a" : { "x" : 193, "y" : 404 }, "b" : { "x" : 205, "y" : 416 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 199, "y" : 410 } } } } ] }, { "id" : 86147, "reactomeId" : 29370, "displayName" : "ADP", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 211, "y" : 458 }, "minX" : 148, "maxX" : 233, "minY" : 412, "maxY" : 473, "prop" : { "x" : 191, "y" : 443, "width" : 41, "height" : 30 }, "textPosition" : { "x" : 195, "y" : 447 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 227, "y" : 448 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 227, "y" : 448 } } }, "connectors" : [ { "edgeId" : 86141, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 188, "y" : 443 }, "to" : { "x" : 148, "y" : 412 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 180, "y" : 442 }, "b" : { "x" : 188, "y" : 443 }, "c" : { "x" : 185, "y" : 436 }, "type" : "ARROW", "centre" : { "x" : 185, "y" : 436 } } } ] }, { "id" : 86146, "reactomeId" : 29372, "displayName" : "Pi", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 201, "y" : 490 }, "minX" : 148, "maxX" : 218, "minY" : 412, "maxY" : 503, "prop" : { "x" : 186, "y" : 478, "width" : 31, "height" : 25 }, "textPosition" : { "x" : 192, "y" : 480 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 212, "y" : 483 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 212, "y" : 483 } } }, "connectors" : [ { "edgeId" : 86141, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 192, "y" : 475 }, "to" : { "x" : 148, "y" : 412 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 185, "y" : 472 }, "b" : { "x" : 192, "y" : 475 }, "c" : { "x" : 191, "y" : 467 }, "type" : "ARROW", "centre" : { "x" : 191, "y" : 467 } } } ] }, { "id" : 86149, "reactomeId" : 29804, "displayName" : "K+", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 281, "y" : 445 }, "minX" : 148, "maxX" : 300, "minY" : 412, "maxY" : 460, "prop" : { "x" : 263, "y" : 430, "width" : 36, "height" : 30 }, "textPosition" : { "x" : 268, "y" : 434 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 294, "y" : 435 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 294, "y" : 435 } } }, "connectors" : [ { "edgeId" : 86141, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 260, "y" : 440 }, "to" : { "x" : 148, "y" : 412 } } ], "stoichiometry" : { "value" : 2, "shape" : { "a" : { "x" : 198, "y" : 420 }, "b" : { "x" : 210, "y" : 432 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 204, "y" : 426 } } }, "endShape" : { "a" : { "x" : 252, "y" : 442 }, "b" : { "x" : 260, "y" : 440 }, "c" : { "x" : 254, "y" : 434 }, "type" : "ARROW", "centre" : { "x" : 254, "y" : 434 } } } ] }, { "id" : 86148, "reactomeId" : 74113, "displayName" : "Na+", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 68, "y" : 436 }, "minX" : 47, "maxX" : 148, "minY" : 412, "maxY" : 451, "prop" : { "x" : 47, "y" : 421, "width" : 42, "height" : 30 }, "textPosition" : { "x" : 50, "y" : 425 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 84, "y" : 426 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 84, "y" : 426 } } }, "connectors" : [ { "edgeId" : 86141, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 92, "y" : 429 }, "to" : { "x" : 148, "y" : 412 } } ], "stoichiometry" : { "value" : 3, "shape" : { "a" : { "x" : 114, "y" : 414 }, "b" : { "x" : 126, "y" : 426 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 120, "y" : 420 } } }, "endShape" : { "a" : { "x" : 97, "y" : 423 }, "b" : { "x" : 92, "y" : 429 }, "c" : { "x" : 100, "y" : 431 }, "type" : "ARROW", "centre" : { "x" : 100, "y" : 431 } } } ] }, { "id" : 86151, "reactomeId" : 10590433, "displayName" : "ATP1A:ATP1B:FXYD:cardiac glycosides", "schemaClass" : "Complex", "renderableClass" : "ComplexDrug", "position" : { "x" : 146, "y" : 183 }, "minX" : 0, "maxX" : 201, "minY" : 151, "maxY" : 409, "prop" : { "x" : 97, "y" : 157, "width" : 98, "height" : 52 }, "textPosition" : { "x" : 99, "y" : 160 }, "bgColor" : { "r" : 184, "g" : 154, "b" : 230 }, "fgColor" : { "r" : 161, "g" : 1, "b" : 2 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 195, "y" : 157 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 195, "y" : 157 } } }, "connectors" : [ { "edgeId" : 86170, "type" : "OUTPUT", "segments" : [ ], "stoichiometry" : { "value" : 1 } }, { "edgeId" : 86141, "type" : "INHIBITOR", "segments" : [ { "from" : { "x" : 94, "y" : 182 }, "to" : { "x" : 0, "y" : 182 } }, { "from" : { "x" : 0, "y" : 182 }, "to" : { "x" : 0, "y" : 332 } }, { "from" : { "x" : 0, "y" : 332 }, "to" : { "x" : 139, "y" : 405 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 137, "y" : 409 }, "b" : { "x" : 141, "y" : 401 }, "c" : { "x" : 139, "y" : 405 }, "type" : "STOP", "centre" : { "x" : 139, "y" : 405 } } } ] }, { "id" : 86150, "reactomeId" : 10590430, "displayName" : "ATP1A:ATP1B:FXYD", "schemaClass" : "Complex", "renderableClass" : "Complex", "position" : { "x" : 147, "y" : 309 }, "minX" : 85, "maxX" : 215, "minY" : 256, "maxY" : 401, "prop" : { "x" : 85, "y" : 298, "width" : 124, "height" : 22 }, "textPosition" : { "x" : 85, "y" : 299 }, "bgColor" : { "r" : 204, "g" : 255, "b" : 255 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 209, "y" : 298 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 209, "y" : 298 } } }, "connectors" : [ { "edgeId" : 86170, "type" : "INPUT", "segments" : [ { "from" : { "x" : 147, "y" : 295 }, "to" : { "x" : 147, "y" : 256 } } ], "stoichiometry" : { "value" : 1 } }, { "edgeId" : 86141, "type" : "CATALYST", "segments" : [ { "from" : { "x" : 147, "y" : 323 }, "to" : { "x" : 147, "y" : 393 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "c" : { "x" : 147, "y" : 397 }, "r" : 4, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 147, "y" : 397 } } } ] }, { "id" : 86153, "reactomeId" : 74112, "displayName" : "Ca2+", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 269, "y" : 919 }, "minX" : 244, "maxX" : 296, "minY" : 903, "maxY" : 934, "prop" : { "x" : 244, "y" : 904, "width" : 51, "height" : 30 }, "textPosition" : { "x" : 248, "y" : 908 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 290, "y" : 909 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 290, "y" : 909 } } }, "connectors" : [ { "edgeId" : 86152, "type" : "INPUT", "segments" : [ ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 86155, "reactomeId" : 10601018, "displayName" : "STIM1:TRPC1", "schemaClass" : "Complex", "renderableClass" : "Complex", "position" : { "x" : 381, "y" : 862 }, "minX" : 310, "maxX" : 431, "minY" : 845, "maxY" : 873, "prop" : { "x" : 338, "y" : 851, "width" : 87, "height" : 22 }, "textPosition" : { "x" : 338, "y" : 852 }, "bgColor" : { "r" : 204, "g" : 255, "b" : 255 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 425, "y" : 851 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 425, "y" : 851 } } }, "connectors" : [ { "edgeId" : 86152, "type" : "CATALYST", "segments" : [ { "from" : { "x" : 335, "y" : 861 }, "to" : { "x" : 318, "y" : 861 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "c" : { "x" : 314, "y" : 861 }, "r" : 4, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 314, "y" : 861 } } } ] }, { "id" : 86154, "reactomeId" : 74016, "displayName" : "Ca2+", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 268, "y" : 808 }, "minX" : 243, "maxX" : 295, "minY" : 792, "maxY" : 823, "prop" : { "x" : 243, "y" : 793, "width" : 51, "height" : 30 }, "textPosition" : { "x" : 247, "y" : 797 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 289, "y" : 798 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 289, "y" : 798 } } }, "connectors" : [ { "edgeId" : 86152, "type" : "OUTPUT", "segments" : [ ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 86157, "reactomeId" : 74016, "displayName" : "Ca2+", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 1207, "y" : 807 }, "minX" : 1182, "maxX" : 1234, "minY" : 791, "maxY" : 822, "prop" : { "x" : 1182, "y" : 792, "width" : 51, "height" : 30 }, "textPosition" : { "x" : 1186, "y" : 796 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1228, "y" : 797 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1228, "y" : 797 } } }, "connectors" : [ { "edgeId" : 86156, "type" : "INPUT", "segments" : [ ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 86159, "reactomeId" : 10584022, "displayName" : "ATP2B1-4", "schemaClass" : "DefinedSet", "renderableClass" : "EntitySet", "position" : { "x" : 1138, "y" : 861 }, "minX" : 1101, "maxX" : 1198, "minY" : 850, "maxY" : 872, "prop" : { "x" : 1101, "y" : 850, "width" : 74, "height" : 22 }, "textPosition" : { "x" : 1104, "y" : 850 }, "connectors" : [ { "edgeId" : 86156, "type" : "CATALYST", "segments" : [ { "from" : { "x" : 1181, "y" : 861 }, "to" : { "x" : 1190, "y" : 861 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "c" : { "x" : 1194, "y" : 861 }, "r" : 4, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1194, "y" : 861 } } } ] }, { "id" : 86158, "reactomeId" : 74112, "displayName" : "Ca2+", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 1207, "y" : 930 }, "minX" : 1182, "maxX" : 1234, "minY" : 914, "maxY" : 945, "prop" : { "x" : 1182, "y" : 915, "width" : 51, "height" : 30 }, "textPosition" : { "x" : 1186, "y" : 919 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1228, "y" : 920 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1228, "y" : 920 } } }, "connectors" : [ { "edgeId" : 86156, "type" : "OUTPUT", "segments" : [ ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 86161, "reactomeId" : 10582758, "displayName" : "Homologues of TNNI3", "schemaClass" : "DefinedSet", "renderableClass" : "EntitySet", "position" : { "x" : 759, "y" : 821 }, "minX" : 736, "maxX" : 782, "minY" : 786, "maxY" : 832, "prop" : { "x" : 736, "y" : 810, "width" : 46, "height" : 22 }, "textPosition" : { "x" : 737, "y" : 790 }, "connectors" : [ { "edgeId" : 86160, "type" : "INPUT", "segments" : [ { "from" : { "x" : 758, "y" : 807 }, "to" : { "x" : 758, "y" : 786 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 86163, "reactomeId" : 10613252, "displayName" : "Homologues of p-S23,S24-TNNI3", "schemaClass" : "DefinedSet", "renderableClass" : "EntitySet", "position" : { "x" : 759, "y" : 686 }, "minX" : 700, "maxX" : 818, "minY" : 676, "maxY" : 738, "prop" : { "x" : 700, "y" : 676, "width" : 118, "height" : 21 }, "textPosition" : { "x" : 700, "y" : 669 }, "connectors" : [ { "edgeId" : 86160, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 758, "y" : 700 }, "to" : { "x" : 758, "y" : 738 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 762, "y" : 707 }, "b" : { "x" : 758, "y" : 700 }, "c" : { "x" : 754, "y" : 707 }, "type" : "ARROW", "centre" : { "x" : 754, "y" : 707 } } } ] }, { "id" : 86162, "reactomeId" : 113592, "displayName" : "ATP", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 813, "y" : 806 }, "minX" : 758, "maxX" : 834, "minY" : 786, "maxY" : 821, "prop" : { "x" : 793, "y" : 791, "width" : 40, "height" : 30 }, "textPosition" : { "x" : 797, "y" : 795 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 828, "y" : 796 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 828, "y" : 796 } } }, "connectors" : [ { "edgeId" : 86160, "type" : "INPUT", "segments" : [ { "from" : { "x" : 790, "y" : 798 }, "to" : { "x" : 758, "y" : 786 } } ], "stoichiometry" : { "value" : 2, "shape" : { "a" : { "x" : 768, "y" : 786 }, "b" : { "x" : 780, "y" : 798 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 774, "y" : 792 } } } } ] }, { "id" : 86165, "reactomeId" : 10566882, "displayName" : "PRKACA", "schemaClass" : "EntityWithAccessionedSequence", "renderableClass" : "Protein", "position" : { "x" : 647, "y" : 768 }, "minX" : 619, "maxX" : 750, "minY" : 751, "maxY" : 779, "prop" : { "x" : 619, "y" : 757, "width" : 56, "height" : 22 }, "textPosition" : { "x" : 619, "y" : 757 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 675, "y" : 757 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 675, "y" : 757 } } }, "connectors" : [ { "edgeId" : 86160, "type" : "CATALYST", "segments" : [ { "from" : { "x" : 678, "y" : 766 }, "to" : { "x" : 742, "y" : 762 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "c" : { "x" : 746, "y" : 762 }, "r" : 4, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 746, "y" : 762 } } } ] }, { "id" : 86164, "reactomeId" : 29370, "displayName" : "ADP", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 813, "y" : 720 }, "minX" : 758, "maxX" : 836, "minY" : 704, "maxY" : 738, "prop" : { "x" : 792, "y" : 705, "width" : 43, "height" : 30 }, "textPosition" : { "x" : 797, "y" : 709 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 830, "y" : 710 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 830, "y" : 710 } } }, "connectors" : [ { "edgeId" : 86160, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 789, "y" : 727 }, "to" : { "x" : 758, "y" : 738 } } ], "stoichiometry" : { "value" : 2, "shape" : { "a" : { "x" : 767, "y" : 726 }, "b" : { "x" : 779, "y" : 738 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 773, "y" : 732 } } }, "endShape" : { "a" : { "x" : 784, "y" : 733 }, "b" : { "x" : 789, "y" : 727 }, "c" : { "x" : 781, "y" : 726 }, "type" : "ARROW", "centre" : { "x" : 781, "y" : 726 } } } ] }, { "id" : 86167, "reactomeId" : 10621231, "displayName" : "NPR1 dimer", "schemaClass" : "Complex", "renderableClass" : "Complex", "position" : { "x" : 1668, "y" : 593 }, "minX" : 1628, "maxX" : 1731, "minY" : 576, "maxY" : 630, "prop" : { "x" : 1628, "y" : 582, "width" : 81, "height" : 22 }, "textPosition" : { "x" : 1628, "y" : 583 }, "bgColor" : { "r" : 204, "g" : 255, "b" : 255 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1709, "y" : 582 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1709, "y" : 582 } } }, "connectors" : [ { "edgeId" : 86166, "type" : "INPUT", "segments" : [ { "from" : { "x" : 1686, "y" : 607 }, "to" : { "x" : 1731, "y" : 630 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 86169, "reactomeId" : 10621233, "displayName" : "NPPA(124-151):NPR1 dimer", "schemaClass" : "Complex", "renderableClass" : "Complex", "position" : { "x" : 1683, "y" : 675 }, "minX" : 1630, "maxX" : 1743, "minY" : 651, "maxY" : 693, "prop" : { "x" : 1630, "y" : 657, "width" : 107, "height" : 36 }, "textPosition" : { "x" : 1630, "y" : 658 }, "bgColor" : { "r" : 204, "g" : 255, "b" : 255 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1737, "y" : 657 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1737, "y" : 657 } } }, "connectors" : [ { "edgeId" : 86166, "type" : "OUTPUT", "segments" : [ ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 86168, "reactomeId" : 10612834, "displayName" : "Homologues of NPPA(124-151)", "schemaClass" : "DefinedSet", "renderableClass" : "EntitySet", "position" : { "x" : 1759, "y" : 565 }, "minX" : 1708, "maxX" : 1811, "minY" : 554, "maxY" : 630, "prop" : { "x" : 1708, "y" : 554, "width" : 103, "height" : 22 }, "textPosition" : { "x" : 1707, "y" : 548 }, "connectors" : [ { "edgeId" : 86166, "type" : "INPUT", "segments" : [ { "from" : { "x" : 1754, "y" : 579 }, "to" : { "x" : 1731, "y" : 630 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 86171, "reactomeId" : 9684063, "displayName" : "cardiac glycosides", "schemaClass" : "DefinedSet", "renderableClass" : "EntitySetDrug", "position" : { "x" : 72, "y" : 256 }, "minX" : 28, "maxX" : 147, "minY" : 234, "maxY" : 279, "prop" : { "x" : 28, "y" : 234, "width" : 88, "height" : 45 }, "textPosition" : { "x" : 35, "y" : 239 }, "bgColor" : { "r" : 184, "g" : 154, "b" : 230 }, "fgColor" : { "r" : 161, "g" : 1, "b" : 2 }, "connectors" : [ { "edgeId" : 86170, "type" : "INPUT", "segments" : [ { "from" : { "x" : 122, "y" : 256 }, "to" : { "x" : 147, "y" : 256 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 86173, "reactomeId" : 9727597, "displayName" : "sacubitril", "schemaClass" : "ChemicalDrug", "renderableClass" : "ChemicalDrug", "position" : { "x" : 1526, "y" : 558 }, "minX" : 1492, "maxX" : 1561, "minY" : 543, "maxY" : 619, "prop" : { "x" : 1492, "y" : 543, "width" : 69, "height" : 31 }, "textPosition" : { "x" : 1494, "y" : 548 }, "bgColor" : { "r" : 184, "g" : 154, "b" : 230 }, "fgColor" : { "r" : 161, "g" : 1, "b" : 2 }, "connectors" : [ { "edgeId" : 86172, "type" : "INPUT", "segments" : [ { "from" : { "x" : 1526, "y" : 577 }, "to" : { "x" : 1526, "y" : 619 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 86175, "reactomeId" : 30203, "displayName" : "EtOH", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 1481, "y" : 715 }, "minX" : 1458, "maxX" : 1526, "minY" : 685, "maxY" : 731, "prop" : { "x" : 1458, "y" : 700, "width" : 46, "height" : 31 }, "textPosition" : { "x" : 1461, "y" : 705 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1499, "y" : 705 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1499, "y" : 705 } } }, "connectors" : [ { "edgeId" : 86172, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 1504, "y" : 697 }, "to" : { "x" : 1526, "y" : 685 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 1508, "y" : 690 }, "b" : { "x" : 1504, "y" : 697 }, "c" : { "x" : 1512, "y" : 697 }, "type" : "ARROW", "centre" : { "x" : 1512, "y" : 697 } } } ] }, { "id" : 86174, "reactomeId" : 29356, "displayName" : "H2O", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 1486, "y" : 597 }, "minX" : 1465, "maxX" : 1526, "minY" : 581, "maxY" : 619, "prop" : { "x" : 1465, "y" : 582, "width" : 43, "height" : 31 }, "textPosition" : { "x" : 1469, "y" : 587 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1503, "y" : 587 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1503, "y" : 587 } } }, "connectors" : [ { "edgeId" : 86172, "type" : "INPUT", "segments" : [ { "from" : { "x" : 1511, "y" : 608 }, "to" : { "x" : 1526, "y" : 619 } } ], "stoichiometry" : { "value" : 1 } } ], "trivial" : true }, { "id" : 86177, "reactomeId" : 10641267, "displayName" : "CES1 trimer", "schemaClass" : "Complex", "renderableClass" : "Complex", "position" : { "x" : 1404, "y" : 663 }, "minX" : 1366, "maxX" : 1518, "minY" : 646, "maxY" : 675, "prop" : { "x" : 1366, "y" : 652, "width" : 77, "height" : 23 }, "textPosition" : { "x" : 1382, "y" : 640 }, "bgColor" : { "r" : 204, "g" : 255, "b" : 255 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1443, "y" : 652 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1443, "y" : 652 } } }, "connectors" : [ { "edgeId" : 86172, "type" : "CATALYST", "segments" : [ { "from" : { "x" : 1446, "y" : 663 }, "to" : { "x" : 1510, "y" : 663 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "c" : { "x" : 1514, "y" : 663 }, "r" : 4, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1514, "y" : 663 } } } ] }, { "id" : 86176, "reactomeId" : 9727588, "displayName" : "sacubitrilat", "schemaClass" : "ChemicalDrug", "renderableClass" : "ChemicalDrug", "position" : { "x" : 1526, "y" : 756 }, "minX" : 1486, "maxX" : 1566, "minY" : 685, "maxY" : 772, "prop" : { "x" : 1486, "y" : 741, "width" : 80, "height" : 31 }, "textPosition" : { "x" : 1487, "y" : 746 }, "bgColor" : { "r" : 184, "g" : 154, "b" : 230 }, "fgColor" : { "r" : 161, "g" : 1, "b" : 2 }, "connectors" : [ { "edgeId" : 86172, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 1526, "y" : 738 }, "to" : { "x" : 1526, "y" : 685 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 1522, "y" : 731 }, "b" : { "x" : 1526, "y" : 738 }, "c" : { "x" : 1530, "y" : 731 }, "type" : "ARROW", "centre" : { "x" : 1530, "y" : 731 } } } ] }, { "id" : 86119, "reactomeId" : 74126, "displayName" : "K+", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 70, "y" : 619 }, "minX" : 52, "maxX" : 89, "minY" : 603, "maxY" : 634, "prop" : { "x" : 52, "y" : 604, "width" : 36, "height" : 30 }, "textPosition" : { "x" : 57, "y" : 608 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 83, "y" : 609 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 83, "y" : 609 } } }, "connectors" : [ { "edgeId" : 86118, "type" : "INPUT", "segments" : [ ], "stoichiometry" : { "value" : 1 } }, { "edgeId" : 86122, "type" : "OUTPUT", "segments" : [ ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 86121, "reactomeId" : 10594752, "displayName" : "KCNJ tetramer", "schemaClass" : "Complex", "renderableClass" : "Complex", "position" : { "x" : 149, "y" : 570 }, "minX" : 120, "maxX" : 184, "minY" : 548, "maxY" : 603, "prop" : { "x" : 120, "y" : 554, "width" : 58, "height" : 32 }, "textPosition" : { "x" : 120, "y" : 537 }, "bgColor" : { "r" : 204, "g" : 255, "b" : 255 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 178, "y" : 554 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 178, "y" : 554 } } }, "connectors" : [ { "edgeId" : 86118, "type" : "CATALYST", "segments" : [ { "from" : { "x" : 149, "y" : 589 }, "to" : { "x" : 149, "y" : 595 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "c" : { "x" : 149, "y" : 599 }, "r" : 4, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 149, "y" : 599 } } } ] }, { "id" : 86120, "reactomeId" : 29804, "displayName" : "K+", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 219, "y" : 620 }, "minX" : 201, "maxX" : 238, "minY" : 604, "maxY" : 635, "prop" : { "x" : 201, "y" : 605, "width" : 36, "height" : 30 }, "textPosition" : { "x" : 206, "y" : 609 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 232, "y" : 610 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 232, "y" : 610 } } }, "connectors" : [ { "edgeId" : 86118, "type" : "OUTPUT", "segments" : [ ], "stoichiometry" : { "value" : 1 } }, { "edgeId" : 86122, "type" : "INPUT", "segments" : [ ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 86123, "reactomeId" : 10612856, "displayName" : "KCNK dimers", "schemaClass" : "CandidateSet", "renderableClass" : "EntitySet", "position" : { "x" : 149, "y" : 674 }, "minX" : 124, "maxX" : 174, "minY" : 636, "maxY" : 690, "prop" : { "x" : 124, "y" : 658, "width" : 50, "height" : 32 }, "textPosition" : { "x" : 124, "y" : 657 }, "connectors" : [ { "edgeId" : 86122, "type" : "CATALYST", "segments" : [ { "from" : { "x" : 149, "y" : 652 }, "to" : { "x" : 149, "y" : 644 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "c" : { "x" : 149, "y" : 640 }, "r" : 4, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 149, "y" : 640 } } } ] }, { "id" : 86125, "reactomeId" : 29804, "displayName" : "K+", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 935, "y" : 134 }, "minX" : 917, "maxX" : 954, "minY" : 118, "maxY" : 149, "prop" : { "x" : 917, "y" : 119, "width" : 36, "height" : 30 }, "textPosition" : { "x" : 922, "y" : 123 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 948, "y" : 124 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 948, "y" : 124 } } }, "connectors" : [ { "edgeId" : 86124, "type" : "INPUT", "segments" : [ ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 86127, "reactomeId" : 10612793, "displayName" : "KCND tetramer:KCNIP tetramer", "schemaClass" : "Complex", "renderableClass" : "Complex", "position" : { "x" : 1021, "y" : 80 }, "minX" : 942, "maxX" : 1087, "minY" : 56, "maxY" : 98, "prop" : { "x" : 962, "y" : 62, "width" : 119, "height" : 36 }, "textPosition" : { "x" : 969, "y" : 63 }, "bgColor" : { "r" : 204, "g" : 255, "b" : 255 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1081, "y" : 62 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1081, "y" : 62 } } }, "connectors" : [ { "edgeId" : 86124, "type" : "CATALYST", "segments" : [ { "from" : { "x" : 959, "y" : 80 }, "to" : { "x" : 950, "y" : 80 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "c" : { "x" : 946, "y" : 80 }, "r" : 4, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 946, "y" : 80 } } } ] }, { "id" : 86126, "reactomeId" : 74126, "displayName" : "K+", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 935, "y" : 16 }, "minX" : 917, "maxX" : 954, "minY" : 0, "maxY" : 31, "prop" : { "x" : 917, "y" : 1, "width" : 36, "height" : 30 }, "textPosition" : { "x" : 922, "y" : 5 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 948, "y" : 6 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 948, "y" : 6 } } }, "connectors" : [ { "edgeId" : 86124, "type" : "OUTPUT", "segments" : [ ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 86129, "reactomeId" : 74113, "displayName" : "Na+", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 980, "y" : 916 }, "minX" : 942, "maxX" : 1002, "minY" : 865, "maxY" : 931, "prop" : { "x" : 959, "y" : 901, "width" : 42, "height" : 30 }, "textPosition" : { "x" : 962, "y" : 905 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 996, "y" : 906 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 996, "y" : 906 } } }, "connectors" : [ { "edgeId" : 86128, "type" : "INPUT", "segments" : [ { "from" : { "x" : 968, "y" : 898 }, "to" : { "x" : 942, "y" : 865 } } ], "stoichiometry" : { "value" : 3, "shape" : { "a" : { "x" : 949, "y" : 875 }, "b" : { "x" : 961, "y" : 887 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 955, "y" : 881 } } } } ] }, { "id" : 86131, "reactomeId" : 83910, "displayName" : "Na+", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 884, "y" : 808 }, "minX" : 863, "maxX" : 938, "minY" : 792, "maxY" : 862, "prop" : { "x" : 863, "y" : 793, "width" : 42, "height" : 30 }, "textPosition" : { "x" : 866, "y" : 797 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 900, "y" : 798 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 900, "y" : 798 } } }, "connectors" : [ { "edgeId" : 86128, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 899, "y" : 826 }, "to" : { "x" : 938, "y" : 862 } } ], "stoichiometry" : { "value" : 3, "shape" : { "a" : { "x" : 912, "y" : 838 }, "b" : { "x" : 924, "y" : 850 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 918, "y" : 844 } } }, "endShape" : { "a" : { "x" : 907, "y" : 828 }, "b" : { "x" : 899, "y" : 826 }, "c" : { "x" : 901, "y" : 834 }, "type" : "ARROW", "centre" : { "x" : 901, "y" : 834 } } } ] }, { "id" : 86130, "reactomeId" : 74016, "displayName" : "Ca2+", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 989, "y" : 803 }, "minX" : 942, "maxX" : 1016, "minY" : 787, "maxY" : 865, "prop" : { "x" : 964, "y" : 788, "width" : 51, "height" : 30 }, "textPosition" : { "x" : 968, "y" : 792 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1010, "y" : 793 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1010, "y" : 793 } } }, "connectors" : [ { "edgeId" : 86128, "type" : "INPUT", "segments" : [ { "from" : { "x" : 977, "y" : 821 }, "to" : { "x" : 942, "y" : 865 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 86133, "reactomeId" : 10584711, "displayName" : "slc8a1b", "schemaClass" : "EntityWithAccessionedSequence", "renderableClass" : "Protein", "position" : { "x" : 1016, "y" : 863 }, "minX" : 948, "maxX" : 1062, "minY" : 846, "maxY" : 874, "prop" : { "x" : 977, "y" : 852, "width" : 79, "height" : 22 }, "textPosition" : { "x" : 988, "y" : 852 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1056, "y" : 852 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1056, "y" : 852 } } }, "connectors" : [ { "edgeId" : 86128, "type" : "CATALYST", "segments" : [ { "from" : { "x" : 971, "y" : 863 }, "to" : { "x" : 956, "y" : 863 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "c" : { "x" : 952, "y" : 863 }, "r" : 4, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 952, "y" : 863 } } } ] }, { "id" : 86132, "reactomeId" : 74112, "displayName" : "Ca2+", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 896, "y" : 920 }, "minX" : 871, "maxX" : 938, "minY" : 862, "maxY" : 935, "prop" : { "x" : 871, "y" : 905, "width" : 51, "height" : 30 }, "textPosition" : { "x" : 875, "y" : 909 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 917, "y" : 910 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 917, "y" : 910 } } }, "connectors" : [ { "edgeId" : 86128, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 906, "y" : 902 }, "to" : { "x" : 938, "y" : 862 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 907, "y" : 894 }, "b" : { "x" : 906, "y" : 902 }, "c" : { "x" : 913, "y" : 899 }, "type" : "ARROW", "centre" : { "x" : 913, "y" : 899 } } } ] }, { "id" : 86134, "reactomeId" : 10584716, "displayName" : "sri", "schemaClass" : "EntityWithAccessionedSequence", "renderableClass" : "Protein", "position" : { "x" : 1133, "y" : 526 }, "minX" : 566, "maxX" : 1153, "minY" : 509, "maxY" : 854, "prop" : { "x" : 1119, "y" : 515, "width" : 28, "height" : 22 }, "textPosition" : { "x" : 1121, "y" : 515 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1147, "y" : 515 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1147, "y" : 515 } } }, "connectors" : [ { "edgeId" : 86128, "type" : "ACTIVATOR", "segments" : [ { "from" : { "x" : 1121, "y" : 540 }, "to" : { "x" : 967, "y" : 683 } }, { "from" : { "x" : 967, "y" : 683 }, "to" : { "x" : 941, "y" : 854 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 938, "y" : 847 }, "b" : { "x" : 941, "y" : 854 }, "c" : { "x" : 946, "y" : 848 }, "type" : "ARROW", "empty" : true, "centre" : { "x" : 946, "y" : 848 } } }, { "edgeId" : 86135, "type" : "ACTIVATOR", "segments" : [ { "from" : { "x" : 1116, "y" : 526 }, "to" : { "x" : 566, "y" : 526 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 573, "y" : 522 }, "b" : { "x" : 566, "y" : 526 }, "c" : { "x" : 573, "y" : 530 }, "type" : "ARROW", "empty" : true, "centre" : { "x" : 573, "y" : 530 } } } ] }, { "id" : 86137, "reactomeId" : 74016, "displayName" : "Ca2+", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 485, "y" : 574 }, "minX" : 460, "maxX" : 557, "minY" : 527, "maxY" : 589, "prop" : { "x" : 460, "y" : 559, "width" : 51, "height" : 30 }, "textPosition" : { "x" : 464, "y" : 563 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 506, "y" : 564 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 506, "y" : 564 } } }, "connectors" : [ { "edgeId" : 86135, "type" : "INPUT", "segments" : [ { "from" : { "x" : 507, "y" : 556 }, "to" : { "x" : 557, "y" : 527 } } ], "stoichiometry" : { "value" : 2, "shape" : { "a" : { "x" : 526, "y" : 535 }, "b" : { "x" : 538, "y" : 547 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 532, "y" : 541 } } } } ] }, { "id" : 86136, "reactomeId" : 156540, "displayName" : "H+", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 489, "y" : 467 }, "minX" : 471, "maxX" : 557, "minY" : 451, "maxY" : 527, "prop" : { "x" : 471, "y" : 452, "width" : 36, "height" : 30 }, "textPosition" : { "x" : 475, "y" : 456 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 502, "y" : 457 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 502, "y" : 457 } } }, "connectors" : [ { "edgeId" : 86135, "type" : "INPUT", "segments" : [ { "from" : { "x" : 506, "y" : 485 }, "to" : { "x" : 557, "y" : 527 } } ], "stoichiometry" : { "value" : 2, "shape" : { "a" : { "x" : 525, "y" : 500 }, "b" : { "x" : 537, "y" : 512 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 531, "y" : 506 } } } } ], "trivial" : true }, { "id" : 86139, "reactomeId" : 70106, "displayName" : "H+", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 627, "y" : 579 }, "minX" : 558, "maxX" : 646, "minY" : 526, "maxY" : 594, "prop" : { "x" : 609, "y" : 564, "width" : 36, "height" : 30 }, "textPosition" : { "x" : 613, "y" : 568 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 640, "y" : 569 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 640, "y" : 569 } } }, "connectors" : [ { "edgeId" : 86135, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 606, "y" : 565 }, "to" : { "x" : 558, "y" : 526 } } ], "stoichiometry" : { "value" : 2, "shape" : { "a" : { "x" : 576, "y" : 539 }, "b" : { "x" : 588, "y" : 551 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 582, "y" : 545 } } }, "endShape" : { "a" : { "x" : 598, "y" : 564 }, "b" : { "x" : 606, "y" : 565 }, "c" : { "x" : 603, "y" : 558 }, "type" : "ARROW", "centre" : { "x" : 603, "y" : 558 } } } ], "trivial" : true }, { "id" : 86138, "reactomeId" : 111875, "displayName" : "Ca2+", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 588, "y" : 446 }, "minX" : 558, "maxX" : 614, "minY" : 430, "maxY" : 526, "prop" : { "x" : 563, "y" : 431, "width" : 50, "height" : 30 }, "textPosition" : { "x" : 567, "y" : 435 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 608, "y" : 436 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 608, "y" : 436 } } }, "connectors" : [ { "edgeId" : 86135, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 582, "y" : 464 }, "to" : { "x" : 558, "y" : 526 } } ], "stoichiometry" : { "value" : 2, "shape" : { "a" : { "x" : 564, "y" : 489 }, "b" : { "x" : 576, "y" : 501 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 570, "y" : 495 } } }, "endShape" : { "a" : { "x" : 583, "y" : 472 }, "b" : { "x" : 582, "y" : 464 }, "c" : { "x" : 576, "y" : 469 }, "type" : "ARROW", "centre" : { "x" : 576, "y" : 469 } } } ] }, { "id" : 86140, "reactomeId" : 10585003, "displayName" : "ATP2A1-3", "schemaClass" : "DefinedSet", "renderableClass" : "EntitySet", "position" : { "x" : 465, "y" : 525 }, "minX" : 430, "maxX" : 549, "minY" : 514, "maxY" : 536, "prop" : { "x" : 430, "y" : 514, "width" : 71, "height" : 22 }, "textPosition" : { "x" : 432, "y" : 514 }, "connectors" : [ { "edgeId" : 86135, "type" : "CATALYST", "segments" : [ { "from" : { "x" : 507, "y" : 525 }, "to" : { "x" : 541, "y" : 526 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "c" : { "x" : 545, "y" : 526 }, "r" : 4, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 545, "y" : 526 } } } ] }, { "id" : 86143, "reactomeId" : 29356, "displayName" : "H2O", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 208, "y" : 345 }, "minX" : 148, "maxX" : 231, "minY" : 329, "maxY" : 410, "prop" : { "x" : 187, "y" : 330, "width" : 43, "height" : 30 }, "textPosition" : { "x" : 191, "y" : 334 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 225, "y" : 335 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 225, "y" : 335 } } }, "connectors" : [ { "edgeId" : 86141, "type" : "INPUT", "segments" : [ { "from" : { "x" : 194, "y" : 363 }, "to" : { "x" : 148, "y" : 410 } } ], "stoichiometry" : { "value" : 1 } } ], "trivial" : true }, { "id" : 86142, "reactomeId" : 113592, "displayName" : "ATP", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 210, "y" : 380 }, "minX" : 148, "maxX" : 231, "minY" : 364, "maxY" : 410, "prop" : { "x" : 190, "y" : 365, "width" : 40, "height" : 30 }, "textPosition" : { "x" : 194, "y" : 369 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 225, "y" : 370 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 225, "y" : 370 } } }, "connectors" : [ { "edgeId" : 86141, "type" : "INPUT", "segments" : [ { "from" : { "x" : 187, "y" : 389 }, "to" : { "x" : 148, "y" : 410 } } ], "stoichiometry" : { "value" : 1 } } ] } ], "edges" : [ { "id" : 86160, "reactomeId" : 10613255, "displayName" : "PRKACA phosphorylates TNNI3", "schemaClass" : "Reaction", "renderableClass" : "Reaction", "position" : { "x" : 758, "y" : 761 }, "minX" : 752, "maxX" : 764, "minY" : 738, "maxY" : 786, "reactionType" : "transition", "segments" : [ { "from" : { "x" : 758, "y" : 786 }, "to" : { "x" : 758, "y" : 761 } }, { "from" : { "x" : 758, "y" : 761 }, "to" : { "x" : 758, "y" : 738 } } ], "reactionShape" : { "a" : { "x" : 752, "y" : 755 }, "b" : { "x" : 764, "y" : 767 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 758, "y" : 761 } }, "inputs" : [ { "id" : 86161, "points" : [ { "x" : 758, "y" : 807 } ] }, { "id" : 86162, "points" : [ { "x" : 790, "y" : 798 } ], "stoichiometry" : 2 } ], "outputs" : [ { "id" : 86163, "points" : [ { "x" : 758, "y" : 700 } ] }, { "id" : 86164, "points" : [ { "x" : 789, "y" : 727 } ], "stoichiometry" : 2 } ], "catalysts" : [ { "id" : 86165, "points" : [ { "x" : 678, "y" : 766 } ] } ] }, { "id" : 86128, "reactomeId" : 10584718, "displayName" : "SLC8A1,2,3 exchange 3Na+ for Ca2+", "schemaClass" : "Reaction", "renderableClass" : "Reaction", "position" : { "x" : 940, "y" : 863 }, "minX" : 934, "maxX" : 946, "minY" : 857, "maxY" : 869, "reactionType" : "transition", "segments" : [ { "from" : { "x" : 942, "y" : 865 }, "to" : { "x" : 940, "y" : 863 } }, { "from" : { "x" : 940, "y" : 863 }, "to" : { "x" : 938, "y" : 862 } } ], "reactionShape" : { "a" : { "x" : 934, "y" : 857 }, "b" : { "x" : 946, "y" : 869 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 940, "y" : 863 } }, "inputs" : [ { "id" : 86129, "points" : [ { "x" : 968, "y" : 898 } ], "stoichiometry" : 3 }, { "id" : 86130, "points" : [ { "x" : 977, "y" : 821 } ] } ], "outputs" : [ { "id" : 86131, "points" : [ { "x" : 899, "y" : 826 } ], "stoichiometry" : 3 }, { "id" : 86132, "points" : [ { "x" : 906, "y" : 902 } ] } ], "catalysts" : [ { "id" : 86133, "points" : [ { "x" : 971, "y" : 863 } ] } ], "activators" : [ { "id" : 86134, "points" : [ { "x" : 1121, "y" : 540 }, { "x" : 967, "y" : 683 } ] } ] }, { "id" : 86135, "reactomeId" : 10585006, "displayName" : "ATP2A1-3 transport Ca2+ from cytosol to ER lumen", "schemaClass" : "Reaction", "renderableClass" : "Reaction", "position" : { "x" : 557, "y" : 526 }, "minX" : 551, "maxX" : 563, "minY" : 520, "maxY" : 532, "reactionType" : "transition", "segments" : [ { "from" : { "x" : 557, "y" : 527 }, "to" : { "x" : 557, "y" : 526 } }, { "from" : { "x" : 557, "y" : 526 }, "to" : { "x" : 558, "y" : 526 } } ], "reactionShape" : { "a" : { "x" : 551, "y" : 520 }, "b" : { "x" : 563, "y" : 532 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 557, "y" : 526 } }, "inputs" : [ { "id" : 86136, "points" : [ { "x" : 506, "y" : 485 } ], "stoichiometry" : 2 }, { "id" : 86137, "points" : [ { "x" : 507, "y" : 556 } ], "stoichiometry" : 2 } ], "outputs" : [ { "id" : 86138, "points" : [ { "x" : 582, "y" : 464 } ], "stoichiometry" : 2 }, { "id" : 86139, "points" : [ { "x" : 606, "y" : 565 } ], "stoichiometry" : 2 } ], "catalysts" : [ { "id" : 86140, "points" : [ { "x" : 507, "y" : 525 } ] } ], "activators" : [ { "id" : 86134, "points" : [ { "x" : 1116, "y" : 526 } ] } ] }, { "id" : 86166, "reactomeId" : 10621235, "displayName" : "NPPA(124-151) binds NPR1", "schemaClass" : "Reaction", "renderableClass" : "Reaction", "position" : { "x" : 1730, "y" : 631 }, "minX" : 1702, "maxX" : 1736, "minY" : 625, "maxY" : 654, "reactionType" : "binding", "segments" : [ { "from" : { "x" : 1731, "y" : 630 }, "to" : { "x" : 1730, "y" : 631 } }, { "from" : { "x" : 1730, "y" : 631 }, "to" : { "x" : 1702, "y" : 654 } } ], "endShape" : { "a" : { "x" : 1705, "y" : 647 }, "b" : { "x" : 1702, "y" : 654 }, "c" : { "x" : 1710, "y" : 653 }, "type" : "ARROW", "centre" : { "x" : 1710, "y" : 653 } }, "reactionShape" : { "c" : { "x" : 1730, "y" : 631 }, "r" : 5, "type" : "CIRCLE", "centre" : { "x" : 1730, "y" : 631 } }, "inputs" : [ { "id" : 86167, "points" : [ { "x" : 1686, "y" : 607 } ] }, { "id" : 86168, "points" : [ { "x" : 1754, "y" : 579 } ] } ], "outputs" : [ { "id" : 86169 } ] }, { "id" : 86118, "reactomeId" : 10594755, "displayName" : "KCNJs transport K+ from the extracellular region to cytosol", "schemaClass" : "Reaction", "renderableClass" : "Reaction", "position" : { "x" : 149, "y" : 611 }, "minX" : 91, "maxX" : 198, "minY" : 605, "maxY" : 617, "reactionType" : "transition", "segments" : [ { "from" : { "x" : 91, "y" : 617 }, "to" : { "x" : 149, "y" : 611 } }, { "from" : { "x" : 149, "y" : 611 }, "to" : { "x" : 198, "y" : 617 } } ], "endShape" : { "a" : { "x" : 191, "y" : 620 }, "b" : { "x" : 198, "y" : 617 }, "c" : { "x" : 192, "y" : 612 }, "type" : "ARROW", "centre" : { "x" : 192, "y" : 612 } }, "reactionShape" : { "a" : { "x" : 143, "y" : 605 }, "b" : { "x" : 155, "y" : 617 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 149, "y" : 611 } }, "inputs" : [ { "id" : 86119 } ], "outputs" : [ { "id" : 86120 } ], "catalysts" : [ { "id" : 86121, "points" : [ { "x" : 149, "y" : 589 } ] } ] }, { "id" : 86152, "reactomeId" : 10601023, "displayName" : "TRPC1 translocates calcium from the extracellular region to the cytosol", "schemaClass" : "Reaction", "renderableClass" : "Reaction", "position" : { "x" : 302, "y" : 861 }, "minX" : 277, "maxX" : 308, "minY" : 826, "maxY" : 901, "reactionType" : "transition", "segments" : [ { "from" : { "x" : 277, "y" : 901 }, "to" : { "x" : 302, "y" : 861 } }, { "from" : { "x" : 302, "y" : 861 }, "to" : { "x" : 277, "y" : 826 } } ], "endShape" : { "a" : { "x" : 284, "y" : 829 }, "b" : { "x" : 277, "y" : 826 }, "c" : { "x" : 278, "y" : 834 }, "type" : "ARROW", "centre" : { "x" : 278, "y" : 834 } }, "reactionShape" : { "a" : { "x" : 296, "y" : 855 }, "b" : { "x" : 308, "y" : 867 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 302, "y" : 861 } }, "inputs" : [ { "id" : 86153 } ], "outputs" : [ { "id" : 86154 } ], "catalysts" : [ { "id" : 86155, "points" : [ { "x" : 335, "y" : 861 } ] } ] }, { "id" : 86122, "reactomeId" : 10612859, "displayName" : "KCNK dimers transport K+ from cytosol to extracellular region", "schemaClass" : "Reaction", "renderableClass" : "Reaction", "position" : { "x" : 149, "y" : 628 }, "minX" : 91, "maxX" : 198, "minY" : 621, "maxY" : 634, "reactionType" : "transition", "segments" : [ { "from" : { "x" : 198, "y" : 622 }, "to" : { "x" : 149, "y" : 628 } }, { "from" : { "x" : 149, "y" : 628 }, "to" : { "x" : 91, "y" : 621 } } ], "endShape" : { "a" : { "x" : 98, "y" : 618 }, "b" : { "x" : 91, "y" : 621 }, "c" : { "x" : 97, "y" : 626 }, "type" : "ARROW", "centre" : { "x" : 97, "y" : 626 } }, "reactionShape" : { "a" : { "x" : 143, "y" : 622 }, "b" : { "x" : 155, "y" : 634 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 149, "y" : 628 } }, "inputs" : [ { "id" : 86120 } ], "outputs" : [ { "id" : 86119 } ], "catalysts" : [ { "id" : 86123, "points" : [ { "x" : 149, "y" : 652 } ] } ] }, { "id" : 86170, "reactomeId" : 10640254, "displayName" : "ATP1A:ATP1B:FXYD binds cardiac glycosides", "schemaClass" : "Reaction", "renderableClass" : "Reaction", "position" : { "x" : 146, "y" : 256 }, "minX" : 140, "maxX" : 152, "minY" : 212, "maxY" : 262, "reactionType" : "binding", "segments" : [ { "from" : { "x" : 147, "y" : 256 }, "to" : { "x" : 146, "y" : 256 } }, { "from" : { "x" : 146, "y" : 256 }, "to" : { "x" : 146, "y" : 212 } } ], "endShape" : { "a" : { "x" : 150, "y" : 219 }, "b" : { "x" : 146, "y" : 212 }, "c" : { "x" : 142, "y" : 219 }, "type" : "ARROW", "centre" : { "x" : 142, "y" : 219 } }, "reactionShape" : { "c" : { "x" : 146, "y" : 256 }, "r" : 5, "type" : "CIRCLE", "centre" : { "x" : 146, "y" : 256 } }, "inputs" : [ { "id" : 86171, "points" : [ { "x" : 122, "y" : 256 } ] }, { "id" : 86150, "points" : [ { "x" : 147, "y" : 295 } ] } ], "outputs" : [ { "id" : 86151 } ] }, { "id" : 86141, "reactomeId" : 10590435, "displayName" : "ATP1A:ATP1B:FXYD exchanges 3Na+ for 2K+", "schemaClass" : "Reaction", "renderableClass" : "Reaction", "position" : { "x" : 147, "y" : 409 }, "minX" : 141, "maxX" : 153, "minY" : 403, "maxY" : 415, "reactionType" : "transition", "segments" : [ { "from" : { "x" : 148, "y" : 410 }, "to" : { "x" : 147, "y" : 409 } }, { "from" : { "x" : 147, "y" : 409 }, "to" : { "x" : 148, "y" : 412 } } ], "reactionShape" : { "a" : { "x" : 141, "y" : 403 }, "b" : { "x" : 153, "y" : 415 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 147, "y" : 409 } }, "inputs" : [ { "id" : 86142, "points" : [ { "x" : 187, "y" : 389 } ] }, { "id" : 86143, "points" : [ { "x" : 194, "y" : 363 } ] }, { "id" : 86144, "points" : [ { "x" : 251, "y" : 410 } ], "stoichiometry" : 3 }, { "id" : 86145, "points" : [ { "x" : 83, "y" : 402 } ], "stoichiometry" : 2 } ], "outputs" : [ { "id" : 86146, "points" : [ { "x" : 192, "y" : 475 } ] }, { "id" : 86147, "points" : [ { "x" : 188, "y" : 443 } ] }, { "id" : 86148, "points" : [ { "x" : 92, "y" : 429 } ], "stoichiometry" : 3 }, { "id" : 86149, "points" : [ { "x" : 260, "y" : 440 } ], "stoichiometry" : 2 } ], "catalysts" : [ { "id" : 86150, "points" : [ { "x" : 147, "y" : 323 } ] } ], "inhibitors" : [ { "id" : 86151, "points" : [ { "x" : 94, "y" : 182 }, { "x" : 0, "y" : 182 }, { "x" : 0, "y" : 332 } ] } ] }, { "id" : 86172, "reactomeId" : 10641270, "displayName" : "CES1 hydrolyses sacubitril to sacubitrilat", "schemaClass" : "Reaction", "renderableClass" : "Reaction", "position" : { "x" : 1526, "y" : 663 }, "minX" : 1520, "maxX" : 1532, "minY" : 619, "maxY" : 685, "reactionType" : "transition", "segments" : [ { "from" : { "x" : 1526, "y" : 619 }, "to" : { "x" : 1526, "y" : 663 } }, { "from" : { "x" : 1526, "y" : 663 }, "to" : { "x" : 1526, "y" : 685 } } ], "reactionShape" : { "a" : { "x" : 1520, "y" : 657 }, "b" : { "x" : 1532, "y" : 669 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 1526, "y" : 663 } }, "inputs" : [ { "id" : 86173, "points" : [ { "x" : 1526, "y" : 577 } ] }, { "id" : 86174, "points" : [ { "x" : 1511, "y" : 608 } ] } ], "outputs" : [ { "id" : 86175, "points" : [ { "x" : 1504, "y" : 697 } ] }, { "id" : 86176, "points" : [ { "x" : 1526, "y" : 738 } ] } ], "catalysts" : [ { "id" : 86177, "points" : [ { "x" : 1446, "y" : 663 } ] } ] }, { "id" : 86156, "reactomeId" : 10584025, "displayName" : "ATP2B1-4 transport cytosolic Ca2+ to extracellular region", "schemaClass" : "Reaction", "renderableClass" : "Reaction", "position" : { "x" : 1206, "y" : 861 }, "minX" : 1200, "maxX" : 1212, "minY" : 825, "maxY" : 912, "reactionType" : "transition", "segments" : [ { "from" : { "x" : 1206, "y" : 825 }, "to" : { "x" : 1206, "y" : 861 } }, { "from" : { "x" : 1206, "y" : 861 }, "to" : { "x" : 1206, "y" : 912 } } ], "endShape" : { "a" : { "x" : 1202, "y" : 905 }, "b" : { "x" : 1206, "y" : 912 }, "c" : { "x" : 1210, "y" : 905 }, "type" : "ARROW", "centre" : { "x" : 1210, "y" : 905 } }, "reactionShape" : { "a" : { "x" : 1200, "y" : 855 }, "b" : { "x" : 1212, "y" : 867 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 1206, "y" : 861 } }, "inputs" : [ { "id" : 86157 } ], "outputs" : [ { "id" : 86158 } ], "catalysts" : [ { "id" : 86159, "points" : [ { "x" : 1181, "y" : 861 } ] } ] }, { "id" : 86124, "reactomeId" : 10612796, "displayName" : "KCND tetramer:KCNIP tetramer transport K+ from cytosol to extracellular region", "schemaClass" : "Reaction", "renderableClass" : "Reaction", "position" : { "x" : 934, "y" : 80 }, "minX" : 928, "maxX" : 940, "minY" : 34, "maxY" : 116, "reactionType" : "transition", "segments" : [ { "from" : { "x" : 934, "y" : 116 }, "to" : { "x" : 934, "y" : 80 } }, { "from" : { "x" : 934, "y" : 80 }, "to" : { "x" : 934, "y" : 34 } } ], "endShape" : { "a" : { "x" : 938, "y" : 41 }, "b" : { "x" : 934, "y" : 34 }, "c" : { "x" : 930, "y" : 41 }, "type" : "ARROW", "centre" : { "x" : 930, "y" : 41 } }, "reactionShape" : { "a" : { "x" : 928, "y" : 74 }, "b" : { "x" : 940, "y" : 86 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 934, "y" : 80 } }, "inputs" : [ { "id" : 86125 } ], "outputs" : [ { "id" : 86126 } ], "catalysts" : [ { "id" : 86127, "points" : [ { "x" : 959, "y" : 80 } ] } ] } ], "compartments" : [ { "id" : 86193, "reactomeId" : 114580, "displayName" : "platelet dense tubular network lumen", "schemaClass" : "Compartment", "renderableClass" : "Compartment", "position" : { "x" : 1448, "y" : 358 }, "minX" : 1335, "maxX" : 1562, "minY" : 242, "maxY" : 474, "prop" : { "x" : 1335, "y" : 242, "width" : 227, "height" : 232 }, "textPosition" : { "x" : 1348, "y" : 260 }, "insets" : { "x" : 1345, "y" : 252, "width" : 207, "height" : 212 }, "bgColor" : { "r" : 250, "g" : 240, "b" : 240 } }, { "id" : 86209, "reactomeId" : 13977, "displayName" : "lipid droplet", "schemaClass" : "Compartment", "renderableClass" : "Compartment", "position" : { "x" : 1347, "y" : 653 }, "minX" : 1293, "maxX" : 1402, "minY" : 607, "maxY" : 699, "prop" : { "x" : 1293, "y" : 607, "width" : 109, "height" : 92 }, "textPosition" : { "x" : 1298, "y" : 620 }, "insets" : { "x" : 1303, "y" : 617, "width" : 89, "height" : 72 }, "bgColor" : { "r" : 250, "g" : 240, "b" : 240 }, "componentIds" : [ 86177 ] }, { "id" : 86195, "reactomeId" : 261378, "displayName" : "sarcoplasmic reticulum lumen", "schemaClass" : "Compartment", "renderableClass" : "Compartment", "position" : { "x" : 802, "y" : 459 }, "minX" : 401, "maxX" : 1203, "minY" : 387, "maxY" : 531, "prop" : { "x" : 401, "y" : 387, "width" : 802, "height" : 144 }, "textPosition" : { "x" : 706, "y" : 442 }, "insets" : { "x" : 411, "y" : 397, "width" : 782, "height" : 124 }, "bgColor" : { "r" : 250, "g" : 240, "b" : 240 }, "componentIds" : [ 86135, 86140, 86134, 86138, 86136 ] }, { "id" : 86178, "reactomeId" : 70101, "displayName" : "cytosol", "schemaClass" : "Compartment", "renderableClass" : "Compartment", "position" : { "x" : 912, "y" : 470 }, "minX" : 143, "maxX" : 1682, "minY" : 75, "maxY" : 866, "prop" : { "x" : 143, "y" : 75, "width" : 1539, "height" : 791 }, "textPosition" : { "x" : 855, "y" : 182 }, "insets" : { "x" : 153, "y" : 85, "width" : 1519, "height" : 771 }, "bgColor" : { "r" : 250, "g" : 240, "b" : 240 }, "componentIds" : [ 86121, 86118, 86120, 86122, 86123, 86127, 86124, 86125, 86130, 86150, 86141, 86146, 86154, 86152, 86155, 86193, 86195, 86156, 86159, 86157, 86139, 86137, 86165, 86160, 86163, 86164, 86161, 86162, 86143, 86147, 86142, 86131, 86133, 86128, 86144, 86149, 86151, 86170, 86209, 86167, 86169, 86176, 86173, 86172, 86174, 86175 ] } ], "notes" : [ ], "links" : [ ], "shadows" : [ { "id" : 86211, "reactomeId" : 10649440, "displayName" : "Phase 4 - resting membrane potential", "schemaClass" : "Pathway", "renderableClass" : "Shadow", "position" : { "x" : 144, "y" : 622 }, "minX" : 42, "maxX" : 247, "minY" : 544, "maxY" : 700, "prop" : { "x" : 42, "y" : 544, "width" : 205, "height" : 156 }, "points" : [ { "x" : 42, "y" : 544 }, { "x" : 247, "y" : 544 }, { "x" : 247, "y" : 700 }, { "x" : 42, "y" : 700 } ], "colour" : "#dc3912" }, { "id" : 86210, "reactomeId" : 10649046, "displayName" : "Ion homeostasis", "schemaClass" : "Pathway", "renderableClass" : "Shadow", "position" : { "x" : 630, "y" : 551 }, "minX" : 18, "maxX" : 1243, "minY" : 147, "maxY" : 955, "prop" : { "x" : 18, "y" : 700, "width" : 1225, "height" : 255 }, "points" : [ { "x" : 18, "y" : 147 }, { "x" : 1243, "y" : 147 }, { "x" : 1243, "y" : 955 }, { "x" : 18, "y" : 955 } ], "colour" : "#4684ee" }, { "id" : 86213, "reactomeId" : 10650136, "displayName" : "Physiological factors", "schemaClass" : "Pathway", "renderableClass" : "Shadow", "position" : { "x" : 1588, "y" : 657 }, "minX" : 1356, "maxX" : 1821, "minY" : 533, "maxY" : 782, "prop" : { "x" : 1356, "y" : 533, "width" : 465, "height" : 249 }, "points" : [ { "x" : 1356, "y" : 533 }, { "x" : 1821, "y" : 533 }, { "x" : 1821, "y" : 782 }, { "x" : 1356, "y" : 782 } ], "colour" : "#666666" }, { "id" : 86212, "reactomeId" : 10649926, "displayName" : "Phase 1 - inactivation of fast Na+ channels", "schemaClass" : "Pathway", "renderableClass" : "Shadow", "position" : { "x" : 999, "y" : 75 }, "minX" : 907, "maxX" : 1091, "minY" : -9, "maxY" : 159, "prop" : { "x" : 907, "y" : -9, "width" : 184, "height" : 156 }, "points" : [ { "x" : 907, "y" : -9 }, { "x" : 1091, "y" : -9 }, { "x" : 1091, "y" : 159 }, { "x" : 907, "y" : 159 } ], "colour" : "#008000" } ], "minX" : 0, "maxX" : 1811, "minY" : 0, "maxY" : 945, "disease" : false }