{
  "dbId" : 10648040,
  "stableId" : "R-DRE-9769740",
  "displayName" : "Coagulation pathway",
  "nodes" : [ {
    "id" : 112257,
    "reactomeId" : 10646006,
    "displayName" : "f5",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 912,
      "y" : 510
    },
    "minX" : 811,
    "maxX" : 969,
    "minY" : 486,
    "maxY" : 529,
    "prop" : {
      "x" : 862,
      "y" : 492,
      "width" : 101,
      "height" : 37
    },
    "textPosition" : {
      "x" : 902,
      "y" : 500
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 963,
          "y" : 492
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 963,
          "y" : 492
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 112256,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 859,
          "y" : 500
        },
        "to" : {
          "x" : 811,
          "y" : 490
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 851,
          "y" : 503
        },
        "b" : {
          "x" : 859,
          "y" : 500
        },
        "c" : {
          "x" : 853,
          "y" : 495
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 853,
          "y" : 495
        }
      }
    } ]
  }, {
    "id" : 112258,
    "reactomeId" : 10567991,
    "displayName" : "factor Va",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 813,
      "y" : 528
    },
    "minX" : 767,
    "maxX" : 991,
    "minY" : 216,
    "maxY" : 593,
    "prop" : {
      "x" : 783,
      "y" : 517,
      "width" : 61,
      "height" : 23
    },
    "textPosition" : {
      "x" : 789,
      "y" : 505
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 844,
          "y" : 517
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 844,
          "y" : 517
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 112256,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 812,
          "y" : 514
        },
        "to" : {
          "x" : 811,
          "y" : 490
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 808,
          "y" : 507
        },
        "b" : {
          "x" : 812,
          "y" : 514
        },
        "c" : {
          "x" : 816,
          "y" : 507
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 816,
          "y" : 507
        }
      }
    }, {
      "edgeId" : 112259,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 804,
          "y" : 543
        },
        "to" : {
          "x" : 767,
          "y" : 593
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 112301,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 847,
          "y" : 538
        },
        "to" : {
          "x" : 991,
          "y" : 589
        }
      }, {
        "from" : {
          "x" : 991,
          "y" : 589
        },
        "to" : {
          "x" : 991,
          "y" : 252
        }
      }, {
        "from" : {
          "x" : 991,
          "y" : 252
        },
        "to" : {
          "x" : 892,
          "y" : 216
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 855,
          "y" : 537
        },
        "b" : {
          "x" : 847,
          "y" : 538
        },
        "c" : {
          "x" : 852,
          "y" : 544
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 852,
          "y" : 544
        }
      }
    } ]
  }, {
    "id" : 112260,
    "reactomeId" : 10567973,
    "displayName" : "FVa:FXa",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 1265,
      "y" : 635
    },
    "minX" : 1169,
    "maxX" : 1299,
    "minY" : 423,
    "maxY" : 647,
    "prop" : {
      "x" : 1238,
      "y" : 624,
      "width" : 55,
      "height" : 23
    },
    "textPosition" : {
      "x" : 1248,
      "y" : 612
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1293,
          "y" : 624
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1293,
          "y" : 624
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 112259,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 112261,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 1261,
          "y" : 621
        },
        "to" : {
          "x" : 1204,
          "y" : 441
        }
      }, {
        "from" : {
          "x" : 1204,
          "y" : 441
        },
        "to" : {
          "x" : 1177,
          "y" : 429
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 1173,
          "y" : 427
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1173,
          "y" : 427
        }
      }
    } ]
  }, {
    "id" : 112263,
    "reactomeId" : 10567943,
    "displayName" : "f2",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 1196,
      "y" : 290
    },
    "minX" : 1139,
    "maxX" : 1257,
    "minY" : 266,
    "maxY" : 380,
    "prop" : {
      "x" : 1141,
      "y" : 272,
      "width" : 110,
      "height" : 37
    },
    "textPosition" : {
      "x" : 1186,
      "y" : 280
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1251,
          "y" : 272
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1251,
          "y" : 272
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 112261,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 1189,
          "y" : 312
        },
        "to" : {
          "x" : 1162,
          "y" : 380
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 1190,
          "y" : 320
        },
        "b" : {
          "x" : 1189,
          "y" : 312
        },
        "c" : {
          "x" : 1183,
          "y" : 317
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 1183,
          "y" : 317
        }
      }
    }, {
      "edgeId" : 112304,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 1182,
          "y" : 312
        },
        "to" : {
          "x" : 1139,
          "y" : 369
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 1181,
          "y" : 320
        },
        "b" : {
          "x" : 1182,
          "y" : 312
        },
        "c" : {
          "x" : 1175,
          "y" : 315
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 1175,
          "y" : 315
        }
      }
    } ]
  }, {
    "id" : 112262,
    "reactomeId" : 10567941,
    "displayName" : "f2",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 1151,
      "y" : 514
    },
    "minX" : 1096,
    "maxX" : 1212,
    "minY" : 490,
    "maxY" : 533,
    "prop" : {
      "x" : 1096,
      "y" : 496,
      "width" : 110,
      "height" : 37
    },
    "textPosition" : {
      "x" : 1141,
      "y" : 504
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1206,
          "y" : 496
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1206,
          "y" : 496
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 112261,
      "type" : "INPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 112304,
      "type" : "INPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 112264,
    "reactomeId" : 10567976,
    "displayName" : "Va:Xa:Factor Xa inhibitors",
    "schemaClass" : "Complex",
    "renderableClass" : "ComplexDrug",
    "position" : {
      "x" : 1346,
      "y" : 335
    },
    "minX" : 1168,
    "maxX" : 1405,
    "minY" : 311,
    "maxY" : 422,
    "prop" : {
      "x" : 1294,
      "y" : 317,
      "width" : 105,
      "height" : 37
    },
    "textPosition" : {
      "x" : 1301,
      "y" : 319
    },
    "bgColor" : {
      "r" : 184,
      "g" : 154,
      "b" : 230
    },
    "fgColor" : {
      "r" : 161,
      "g" : 1,
      "b" : 2
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1399,
          "y" : 317
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1399,
          "y" : 317
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 112261,
      "type" : "INHIBITOR",
      "segments" : [ {
        "from" : {
          "x" : 1306,
          "y" : 357
        },
        "to" : {
          "x" : 1170,
          "y" : 418
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 1168,
          "y" : 414
        },
        "b" : {
          "x" : 1172,
          "y" : 422
        },
        "c" : {
          "x" : 1170,
          "y" : 418
        },
        "type" : "STOP",
        "centre" : {
          "x" : 1170,
          "y" : 418
        }
      }
    } ]
  }, {
    "id" : 112267,
    "reactomeId" : 947594,
    "displayName" : "APLs",
    "schemaClass" : "DefinedSet",
    "renderableClass" : "EntitySet",
    "position" : {
      "x" : 1440,
      "y" : 381
    },
    "minX" : 1422,
    "maxX" : 1458,
    "minY" : 370,
    "maxY" : 393,
    "prop" : {
      "x" : 1422,
      "y" : 370,
      "width" : 36,
      "height" : 23
    },
    "textPosition" : {
      "x" : 1425,
      "y" : 364
    },
    "connectors" : [ {
      "edgeId" : 112265,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 112266,
    "reactomeId" : 947588,
    "displayName" : "APLs",
    "schemaClass" : "DefinedSet",
    "renderableClass" : "EntitySet",
    "position" : {
      "x" : 1379,
      "y" : 415
    },
    "minX" : 1361,
    "maxX" : 1397,
    "minY" : 404,
    "maxY" : 427,
    "prop" : {
      "x" : 1361,
      "y" : 404,
      "width" : 36,
      "height" : 23
    },
    "textPosition" : {
      "x" : 1364,
      "y" : 398
    },
    "connectors" : [ {
      "edgeId" : 112265,
      "type" : "INPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 112268,
    "reactomeId" : 10644629,
    "displayName" : "ANO6:ANO6:Ca2+",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 1272,
      "y" : 430
    },
    "minX" : 1213,
    "maxX" : 1337,
    "minY" : 372,
    "maxY" : 442,
    "prop" : {
      "x" : 1213,
      "y" : 419,
      "width" : 118,
      "height" : 23
    },
    "textPosition" : {
      "x" : 1213,
      "y" : 421
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1331,
          "y" : 419
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1331,
          "y" : 419
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 112265,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 1276,
          "y" : 416
        },
        "to" : {
          "x" : 1294,
          "y" : 374
        }
      }, {
        "from" : {
          "x" : 1294,
          "y" : 374
        },
        "to" : {
          "x" : 1299,
          "y" : 375
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 1303,
          "y" : 376
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1303,
          "y" : 376
        }
      }
    } ]
  }, {
    "id" : 112270,
    "reactomeId" : 10640126,
    "displayName" : "f9b",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 174,
      "y" : 1112
    },
    "minX" : 135,
    "maxX" : 219,
    "minY" : 1095,
    "maxY" : 1124,
    "prop" : {
      "x" : 135,
      "y" : 1101,
      "width" : 78,
      "height" : 23
    },
    "textPosition" : {
      "x" : 160,
      "y" : 1102
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 213,
          "y" : 1101
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 213,
          "y" : 1101
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 112269,
      "type" : "INPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 112272,
    "reactomeId" : 10612913,
    "displayName" : "factor IXa",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 1633,
      "y" : 1034
    },
    "minX" : 1601,
    "maxX" : 1671,
    "minY" : 1017,
    "maxY" : 1046,
    "prop" : {
      "x" : 1601,
      "y" : 1023,
      "width" : 64,
      "height" : 23
    },
    "textPosition" : {
      "x" : 1608,
      "y" : 1011
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1665,
          "y" : 1023
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1665,
          "y" : 1023
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 112271,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 112275,
    "reactomeId" : 10567611,
    "displayName" : "fibrin monomer",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 2007,
      "y" : 306
    },
    "minX" : 1904,
    "maxX" : 2083,
    "minY" : 289,
    "maxY" : 318,
    "prop" : {
      "x" : 1958,
      "y" : 295,
      "width" : 98,
      "height" : 23
    },
    "textPosition" : {
      "x" : 1973,
      "y" : 283
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 2056,
          "y" : 295
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 2056,
          "y" : 295
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 112273,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 1955,
          "y" : 305
        },
        "to" : {
          "x" : 1904,
          "y" : 304
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 1948,
          "y" : 309
        },
        "b" : {
          "x" : 1955,
          "y" : 305
        },
        "c" : {
          "x" : 1948,
          "y" : 301
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 1948,
          "y" : 301
        }
      }
    }, {
      "edgeId" : 112280,
      "type" : "INPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 3,
        "shape" : {
          "a" : {
            "x" : 2071,
            "y" : 298
          },
          "b" : {
            "x" : 2083,
            "y" : 310
          },
          "type" : "BOX",
          "empty" : true,
          "centre" : {
            "x" : 2077,
            "y" : 304
          }
        }
      }
    } ]
  }, {
    "id" : 112274,
    "reactomeId" : 10568248,
    "displayName" : "Fibrinogen",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 1808,
      "y" : 306
    },
    "minX" : 1774,
    "maxX" : 1849,
    "minY" : 289,
    "maxY" : 318,
    "prop" : {
      "x" : 1774,
      "y" : 295,
      "width" : 69,
      "height" : 23
    },
    "textPosition" : {
      "x" : 1775,
      "y" : 283
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1843,
          "y" : 295
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1843,
          "y" : 295
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 112273,
      "type" : "INPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 112277,
    "reactomeId" : 10568252,
    "displayName" : "fgb",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 1997,
      "y" : 350
    },
    "minX" : 1904,
    "maxX" : 2042,
    "minY" : 304,
    "maxY" : 362,
    "prop" : {
      "x" : 1958,
      "y" : 339,
      "width" : 78,
      "height" : 23
    },
    "textPosition" : {
      "x" : 1983,
      "y" : 340
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 2036,
          "y" : 339
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 2036,
          "y" : 339
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 112273,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 1973,
          "y" : 336
        },
        "to" : {
          "x" : 1904,
          "y" : 304
        }
      } ],
      "stoichiometry" : {
        "value" : 2,
        "shape" : {
          "a" : {
            "x" : 1932,
            "y" : 314
          },
          "b" : {
            "x" : 1944,
            "y" : 326
          },
          "type" : "BOX",
          "empty" : true,
          "centre" : {
            "x" : 1938,
            "y" : 320
          }
        }
      },
      "endShape" : {
        "a" : {
          "x" : 1965,
          "y" : 337
        },
        "b" : {
          "x" : 1973,
          "y" : 336
        },
        "c" : {
          "x" : 1968,
          "y" : 329
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 1968,
          "y" : 329
        }
      }
    } ]
  }, {
    "id" : 112276,
    "reactomeId" : 10568250,
    "displayName" : "fga",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 1896,
      "y" : 353
    },
    "minX" : 1857,
    "maxX" : 1942,
    "minY" : 304,
    "maxY" : 365,
    "prop" : {
      "x" : 1857,
      "y" : 342,
      "width" : 79,
      "height" : 23
    },
    "textPosition" : {
      "x" : 1882,
      "y" : 343
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1936,
          "y" : 342
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1936,
          "y" : 342
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 112273,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 1897,
          "y" : 339
        },
        "to" : {
          "x" : 1904,
          "y" : 304
        }
      } ],
      "stoichiometry" : {
        "value" : 2,
        "shape" : {
          "a" : {
            "x" : 1894,
            "y" : 315
          },
          "b" : {
            "x" : 1906,
            "y" : 327
          },
          "type" : "BOX",
          "empty" : true,
          "centre" : {
            "x" : 1900,
            "y" : 321
          }
        }
      },
      "endShape" : {
        "a" : {
          "x" : 1894,
          "y" : 331
        },
        "b" : {
          "x" : 1897,
          "y" : 339
        },
        "c" : {
          "x" : 1902,
          "y" : 333
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 1902,
          "y" : 333
        }
      }
    } ]
  }, {
    "id" : 112279,
    "reactomeId" : 10567903,
    "displayName" : "Extracellular thrombin inactivating complexes",
    "schemaClass" : "DefinedSet",
    "renderableClass" : "EntitySet",
    "position" : {
      "x" : 1865,
      "y" : 185
    },
    "minX" : 1799,
    "maxX" : 1932,
    "minY" : 129,
    "maxY" : 295,
    "prop" : {
      "x" : 1799,
      "y" : 160,
      "width" : 133,
      "height" : 51
    },
    "textPosition" : {
      "x" : 1821,
      "y" : 154
    },
    "connectors" : [ {
      "edgeId" : 112273,
      "type" : "INHIBITOR",
      "segments" : [ {
        "from" : {
          "x" : 1867,
          "y" : 217
        },
        "to" : {
          "x" : 1874,
          "y" : 295
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 1870,
          "y" : 295
        },
        "b" : {
          "x" : 1878,
          "y" : 295
        },
        "c" : {
          "x" : 1874,
          "y" : 295
        },
        "type" : "STOP",
        "centre" : {
          "x" : 1874,
          "y" : 295
        }
      }
    }, {
      "edgeId" : 112282,
      "type" : "INHIBITOR",
      "segments" : [ {
        "from" : {
          "x" : 1896,
          "y" : 154
        },
        "to" : {
          "x" : 1929,
          "y" : 132
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 1927,
          "y" : 129
        },
        "b" : {
          "x" : 1931,
          "y" : 135
        },
        "c" : {
          "x" : 1929,
          "y" : 132
        },
        "type" : "STOP",
        "centre" : {
          "x" : 1929,
          "y" : 132
        }
      }
    } ]
  }, {
    "id" : 112278,
    "reactomeId" : 10567923,
    "displayName" : "Factor IIa inhibitors:IIa",
    "schemaClass" : "DefinedSet",
    "renderableClass" : "EntitySetDrug",
    "position" : {
      "x" : 1957,
      "y" : 259
    },
    "minX" : 1881,
    "maxX" : 2018,
    "minY" : 132,
    "maxY" : 305,
    "prop" : {
      "x" : 1896,
      "y" : 241,
      "width" : 122,
      "height" : 37
    },
    "textPosition" : {
      "x" : 1915,
      "y" : 242
    },
    "bgColor" : {
      "r" : 184,
      "g" : 154,
      "b" : 230
    },
    "fgColor" : {
      "r" : 161,
      "g" : 1,
      "b" : 2
    },
    "connectors" : [ {
      "edgeId" : 112273,
      "type" : "INHIBITOR",
      "segments" : [ {
        "from" : {
          "x" : 1923,
          "y" : 284
        },
        "to" : {
          "x" : 1883,
          "y" : 301
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 1881,
          "y" : 297
        },
        "b" : {
          "x" : 1885,
          "y" : 305
        },
        "c" : {
          "x" : 1883,
          "y" : 301
        },
        "type" : "STOP",
        "centre" : {
          "x" : 1883,
          "y" : 301
        }
      }
    }, {
      "edgeId" : 112282,
      "type" : "INHIBITOR",
      "segments" : [ {
        "from" : {
          "x" : 1965,
          "y" : 235
        },
        "to" : {
          "x" : 1985,
          "y" : 195
        }
      }, {
        "from" : {
          "x" : 1985,
          "y" : 195
        },
        "to" : {
          "x" : 1941,
          "y" : 134
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 1938,
          "y" : 136
        },
        "b" : {
          "x" : 1944,
          "y" : 132
        },
        "c" : {
          "x" : 1941,
          "y" : 134
        },
        "type" : "STOP",
        "centre" : {
          "x" : 1941,
          "y" : 134
        }
      }
    } ]
  }, {
    "id" : 112281,
    "reactomeId" : 10567613,
    "displayName" : "fibrin multimer",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 2174,
      "y" : 306
    },
    "minX" : 1943,
    "maxX" : 2227,
    "minY" : 132,
    "maxY" : 362,
    "prop" : {
      "x" : 2127,
      "y" : 295,
      "width" : 94,
      "height" : 23
    },
    "textPosition" : {
      "x" : 2143,
      "y" : 283
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 2221,
          "y" : 295
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 2221,
          "y" : 295
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 112280,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 112282,
      "type" : "ACTIVATOR",
      "segments" : [ {
        "from" : {
          "x" : 2158,
          "y" : 292
        },
        "to" : {
          "x" : 1943,
          "y" : 132
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 1951,
          "y" : 133
        },
        "b" : {
          "x" : 1943,
          "y" : 132
        },
        "c" : {
          "x" : 1946,
          "y" : 139
        },
        "type" : "ARROW",
        "empty" : true,
        "centre" : {
          "x" : 1946,
          "y" : 139
        }
      }
    }, {
      "edgeId" : 112291,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 2175,
          "y" : 321
        },
        "to" : {
          "x" : 2183,
          "y" : 362
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 112294,
      "type" : "INPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 112283,
    "reactomeId" : 10567855,
    "displayName" : "factor XIII",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 1805,
      "y" : 130
    },
    "minX" : 1774,
    "maxX" : 1843,
    "minY" : 113,
    "maxY" : 142,
    "prop" : {
      "x" : 1774,
      "y" : 119,
      "width" : 63,
      "height" : 23
    },
    "textPosition" : {
      "x" : 1781,
      "y" : 107
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1837,
          "y" : 119
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1837,
          "y" : 119
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 112282,
      "type" : "INPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 112285,
    "reactomeId" : 10567859,
    "displayName" : "factor XIII cleaved tetramer",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 2079,
      "y" : 131
    },
    "minX" : 1972,
    "maxX" : 2163,
    "minY" : 107,
    "maxY" : 150,
    "prop" : {
      "x" : 2022,
      "y" : 113,
      "width" : 115,
      "height" : 37
    },
    "textPosition" : {
      "x" : 2022,
      "y" : 115
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 2137,
          "y" : 113
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 2137,
          "y" : 113
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 112282,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 2019,
          "y" : 129
        },
        "to" : {
          "x" : 1972,
          "y" : 128
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 2012,
          "y" : 133
        },
        "b" : {
          "x" : 2019,
          "y" : 129
        },
        "c" : {
          "x" : 2012,
          "y" : 125
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 2012,
          "y" : 125
        }
      }
    }, {
      "edgeId" : 112287,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 2140,
          "y" : 129
        },
        "to" : {
          "x" : 2163,
          "y" : 129
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 112284,
    "reactomeId" : 10567861,
    "displayName" : "F13A1(1-37)",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 2013,
      "y" : 76
    },
    "minX" : 1957,
    "maxX" : 2076,
    "minY" : 52,
    "maxY" : 128,
    "prop" : {
      "x" : 1957,
      "y" : 58,
      "width" : 113,
      "height" : 37
    },
    "textPosition" : {
      "x" : 1971,
      "y" : 66
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 2070,
          "y" : 58
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 2070,
          "y" : 58
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 112282,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 1998,
          "y" : 98
        },
        "to" : {
          "x" : 1972,
          "y" : 128
        }
      } ],
      "stoichiometry" : {
        "value" : 2,
        "shape" : {
          "a" : {
            "x" : 1979,
            "y" : 107
          },
          "b" : {
            "x" : 1991,
            "y" : 119
          },
          "type" : "BOX",
          "empty" : true,
          "centre" : {
            "x" : 1985,
            "y" : 113
          }
        }
      },
      "endShape" : {
        "a" : {
          "x" : 1996,
          "y" : 106
        },
        "b" : {
          "x" : 1998,
          "y" : 98
        },
        "c" : {
          "x" : 1990,
          "y" : 101
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 1990,
          "y" : 101
        }
      }
    } ]
  }, {
    "id" : 112286,
    "reactomeId" : 10567917,
    "displayName" : "SERPINE2:GAG:activated thrombin (factor IIa)",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 2258,
      "y" : 682
    },
    "minX" : 847,
    "maxX" : 2481,
    "minY" : 0,
    "maxY" : 708,
    "prop" : {
      "x" : 2198,
      "y" : 657,
      "width" : 121,
      "height" : 51
    },
    "textPosition" : {
      "x" : 2201,
      "y" : 645
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 2319,
          "y" : 657
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 2319,
          "y" : 657
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 112282,
      "type" : "INHIBITOR",
      "segments" : [ {
        "from" : {
          "x" : 2322,
          "y" : 679
        },
        "to" : {
          "x" : 2456,
          "y" : 673
        }
      }, {
        "from" : {
          "x" : 2456,
          "y" : 673
        },
        "to" : {
          "x" : 2455,
          "y" : 37
        }
      }, {
        "from" : {
          "x" : 2455,
          "y" : 37
        },
        "to" : {
          "x" : 1935,
          "y" : 37
        }
      }, {
        "from" : {
          "x" : 1935,
          "y" : 37
        },
        "to" : {
          "x" : 1936,
          "y" : 118
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 1932,
          "y" : 118
        },
        "b" : {
          "x" : 1940,
          "y" : 118
        },
        "c" : {
          "x" : 1936,
          "y" : 118
        },
        "type" : "STOP",
        "centre" : {
          "x" : 1936,
          "y" : 118
        }
      }
    }, {
      "edgeId" : 112301,
      "type" : "INHIBITOR",
      "segments" : [ {
        "from" : {
          "x" : 2322,
          "y" : 682
        },
        "to" : {
          "x" : 2481,
          "y" : 682
        }
      }, {
        "from" : {
          "x" : 2481,
          "y" : 682
        },
        "to" : {
          "x" : 2474,
          "y" : 1
        }
      }, {
        "from" : {
          "x" : 2474,
          "y" : 1
        },
        "to" : {
          "x" : 852,
          "y" : 0
        }
      }, {
        "from" : {
          "x" : 852,
          "y" : 0
        },
        "to" : {
          "x" : 851,
          "y" : 207
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 847,
          "y" : 207
        },
        "b" : {
          "x" : 855,
          "y" : 207
        },
        "c" : {
          "x" : 851,
          "y" : 207
        },
        "type" : "STOP",
        "centre" : {
          "x" : 851,
          "y" : 207
        }
      }
    } ]
  }, {
    "id" : 112289,
    "reactomeId" : 10568258,
    "displayName" : "factor XIIIa",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 2265,
      "y" : 188
    },
    "minX" : 2212,
    "maxX" : 2306,
    "minY" : 130,
    "maxY" : 348,
    "prop" : {
      "x" : 2230,
      "y" : 177,
      "width" : 70,
      "height" : 23
    },
    "textPosition" : {
      "x" : 2240,
      "y" : 165
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 2300,
          "y" : 177
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 2300,
          "y" : 177
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 112287,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 2254,
          "y" : 174
        },
        "to" : {
          "x" : 2212,
          "y" : 130
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 2246,
          "y" : 172
        },
        "b" : {
          "x" : 2254,
          "y" : 174
        },
        "c" : {
          "x" : 2252,
          "y" : 166
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 2252,
          "y" : 166
        }
      }
    }, {
      "edgeId" : 112294,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 2266,
          "y" : 203
        },
        "to" : {
          "x" : 2279,
          "y" : 288
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 2279,
          "y" : 292
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 2279,
          "y" : 292
        }
      }
    }, {
      "edgeId" : 112297,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 2265,
          "y" : 203
        },
        "to" : {
          "x" : 2266,
          "y" : 340
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 2266,
          "y" : 344
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 2266,
          "y" : 344
        }
      }
    } ]
  }, {
    "id" : 112288,
    "reactomeId" : 74112,
    "displayName" : "Ca2+",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 2151,
      "y" : 85
    },
    "minX" : 2126,
    "maxX" : 2177,
    "minY" : 69,
    "maxY" : 129,
    "prop" : {
      "x" : 2126,
      "y" : 70,
      "width" : 50,
      "height" : 31
    },
    "textPosition" : {
      "x" : 2130,
      "y" : 75
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 2171,
          "y" : 75
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 2171,
          "y" : 75
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 112287,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 2155,
          "y" : 104
        },
        "to" : {
          "x" : 2163,
          "y" : 129
        }
      } ],
      "stoichiometry" : {
        "value" : 2,
        "shape" : {
          "a" : {
            "x" : 2153,
            "y" : 110
          },
          "b" : {
            "x" : 2165,
            "y" : 122
          },
          "type" : "BOX",
          "empty" : true,
          "centre" : {
            "x" : 2159,
            "y" : 116
          }
        }
      }
    } ]
  }, {
    "id" : 112290,
    "reactomeId" : 10567853,
    "displayName" : "cfh",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 2232,
      "y" : 79
    },
    "minX" : 2212,
    "maxX" : 2257,
    "minY" : 62,
    "maxY" : 130,
    "prop" : {
      "x" : 2213,
      "y" : 68,
      "width" : 38,
      "height" : 23
    },
    "textPosition" : {
      "x" : 2218,
      "y" : 69
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 2251,
          "y" : 68
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 2251,
          "y" : 68
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 112287,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 2227,
          "y" : 94
        },
        "to" : {
          "x" : 2212,
          "y" : 130
        }
      } ],
      "stoichiometry" : {
        "value" : 2,
        "shape" : {
          "a" : {
            "x" : 2213,
            "y" : 106
          },
          "b" : {
            "x" : 2225,
            "y" : 118
          },
          "type" : "BOX",
          "empty" : true,
          "centre" : {
            "x" : 2219,
            "y" : 112
          }
        }
      },
      "endShape" : {
        "a" : {
          "x" : 2228,
          "y" : 102
        },
        "b" : {
          "x" : 2227,
          "y" : 94
        },
        "c" : {
          "x" : 2221,
          "y" : 99
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 2221,
          "y" : 99
        }
      }
    } ]
  }, {
    "id" : 112293,
    "reactomeId" : 10567625,
    "displayName" : "Integrin alpha IIb beta 3:fibrin multimer",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 2255,
      "y" : 406
    },
    "minX" : 2200,
    "maxX" : 2316,
    "minY" : 375,
    "maxY" : 432,
    "prop" : {
      "x" : 2200,
      "y" : 381,
      "width" : 110,
      "height" : 51
    },
    "textPosition" : {
      "x" : 2202,
      "y" : 383
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 2310,
          "y" : 381
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 2310,
          "y" : 381
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 112291,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 112297,
      "type" : "INPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 112292,
    "reactomeId" : 10567597,
    "displayName" : "Integrin alphaIIb:beta3",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 2108,
      "y" : 390
    },
    "minX" : 2055,
    "maxX" : 2183,
    "minY" : 362,
    "maxY" : 409,
    "prop" : {
      "x" : 2055,
      "y" : 372,
      "width" : 106,
      "height" : 37
    },
    "textPosition" : {
      "x" : 2059,
      "y" : 374
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 2161,
          "y" : 372
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 2161,
          "y" : 372
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 112291,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 2157,
          "y" : 369
        },
        "to" : {
          "x" : 2183,
          "y" : 362
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 112295,
    "reactomeId" : 157771,
    "displayName" : "fibrin multimer, crosslinked",
    "schemaClass" : "OtherEntity",
    "renderableClass" : "Entity",
    "position" : {
      "x" : 2391,
      "y" : 265
    },
    "minX" : 2306,
    "maxX" : 2442,
    "minY" : 247,
    "maxY" : 304,
    "prop" : {
      "x" : 2340,
      "y" : 247,
      "width" : 102,
      "height" : 37
    },
    "textPosition" : {
      "x" : 2339,
      "y" : 248
    },
    "connectors" : [ {
      "edgeId" : 112294,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 2350,
          "y" : 287
        },
        "to" : {
          "x" : 2306,
          "y" : 304
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 2345,
          "y" : 293
        },
        "b" : {
          "x" : 2350,
          "y" : 287
        },
        "c" : {
          "x" : 2342,
          "y" : 286
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 2342,
          "y" : 286
        }
      }
    } ]
  }, {
    "id" : 112296,
    "reactomeId" : 140912,
    "displayName" : "NH4+",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 2391,
      "y" : 382
    },
    "minX" : 2306,
    "maxX" : 2419,
    "minY" : 304,
    "maxY" : 398,
    "prop" : {
      "x" : 2365,
      "y" : 367,
      "width" : 53,
      "height" : 31
    },
    "textPosition" : {
      "x" : 2369,
      "y" : 372
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 2413,
          "y" : 372
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 2413,
          "y" : 372
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 112294,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 2374,
          "y" : 364
        },
        "to" : {
          "x" : 2306,
          "y" : 304
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 2366,
          "y" : 362
        },
        "b" : {
          "x" : 2374,
          "y" : 364
        },
        "c" : {
          "x" : 2371,
          "y" : 356
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 2371,
          "y" : 356
        }
      }
    }, {
      "edgeId" : 112297,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 2362,
          "y" : 372
        },
        "to" : {
          "x" : 2319,
          "y" : 356
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 2354,
          "y" : 373
        },
        "b" : {
          "x" : 2362,
          "y" : 372
        },
        "c" : {
          "x" : 2357,
          "y" : 366
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 2357,
          "y" : 366
        }
      }
    } ]
  }, {
    "id" : 112298,
    "reactomeId" : 10645803,
    "displayName" : "αIIbβ3:fibrin multimer, crosslinked",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 2296,
      "y" : 504
    },
    "minX" : 2254,
    "maxX" : 2344,
    "minY" : 356,
    "maxY" : 530,
    "prop" : {
      "x" : 2254,
      "y" : 479,
      "width" : 84,
      "height" : 51
    },
    "textPosition" : {
      "x" : 2253,
      "y" : 481
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 2338,
          "y" : 479
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 2338,
          "y" : 479
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 112297,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 2309,
          "y" : 476
        },
        "to" : {
          "x" : 2318,
          "y" : 462
        }
      }, {
        "from" : {
          "x" : 2318,
          "y" : 462
        },
        "to" : {
          "x" : 2319,
          "y" : 356
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 2309,
          "y" : 468
        },
        "b" : {
          "x" : 2309,
          "y" : 476
        },
        "c" : {
          "x" : 2316,
          "y" : 472
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 2316,
          "y" : 472
        }
      }
    } ]
  }, {
    "id" : 112300,
    "reactomeId" : 10646231,
    "displayName" : "FVa intermediate:FXa",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 620,
      "y" : 755
    },
    "minX" : 565,
    "maxX" : 682,
    "minY" : 731,
    "maxY" : 774,
    "prop" : {
      "x" : 565,
      "y" : 737,
      "width" : 111,
      "height" : 37
    },
    "textPosition" : {
      "x" : 574,
      "y" : 725
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 676,
          "y" : 737
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 676,
          "y" : 737
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 112299,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 112303,
    "reactomeId" : 10567903,
    "displayName" : "Extracellular thrombin inactivating complexes",
    "schemaClass" : "DefinedSet",
    "renderableClass" : "EntitySet",
    "position" : {
      "x" : 1150,
      "y" : 1004
    },
    "minX" : 853,
    "maxX" : 1217,
    "minY" : 222,
    "maxY" : 1030,
    "prop" : {
      "x" : 1084,
      "y" : 979,
      "width" : 133,
      "height" : 51
    },
    "textPosition" : {
      "x" : 1106,
      "y" : 973
    },
    "connectors" : [ {
      "edgeId" : 112301,
      "type" : "INHIBITOR",
      "segments" : [ {
        "from" : {
          "x" : 1118,
          "y" : 973
        },
        "to" : {
          "x" : 1075,
          "y" : 944
        }
      }, {
        "from" : {
          "x" : 1075,
          "y" : 944
        },
        "to" : {
          "x" : 1077,
          "y" : 319
        }
      }, {
        "from" : {
          "x" : 1077,
          "y" : 319
        },
        "to" : {
          "x" : 860,
          "y" : 230
        }
      }, {
        "from" : {
          "x" : 860,
          "y" : 230
        },
        "to" : {
          "x" : 856,
          "y" : 224
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 853,
          "y" : 226
        },
        "b" : {
          "x" : 859,
          "y" : 222
        },
        "c" : {
          "x" : 856,
          "y" : 224
        },
        "type" : "STOP",
        "centre" : {
          "x" : 856,
          "y" : 224
        }
      }
    } ]
  }, {
    "id" : 112302,
    "reactomeId" : 10567997,
    "displayName" : "f5",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 959,
      "y" : 183
    },
    "minX" : 892,
    "maxX" : 1023,
    "minY" : 159,
    "maxY" : 216,
    "prop" : {
      "x" : 901,
      "y" : 165,
      "width" : 116,
      "height" : 37
    },
    "textPosition" : {
      "x" : 949,
      "y" : 173
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1017,
          "y" : 165
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1017,
          "y" : 165
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 112301,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 921,
          "y" : 205
        },
        "to" : {
          "x" : 892,
          "y" : 216
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 916,
          "y" : 211
        },
        "b" : {
          "x" : 921,
          "y" : 205
        },
        "c" : {
          "x" : 913,
          "y" : 204
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 913,
          "y" : 204
        }
      }
    } ]
  }, {
    "id" : 112305,
    "reactomeId" : 10568002,
    "displayName" : "factor Xa:Factor Xa inhibitors",
    "schemaClass" : "Complex",
    "renderableClass" : "ComplexDrug",
    "position" : {
      "x" : 1344,
      "y" : 279
    },
    "minX" : 1142,
    "maxX" : 1412,
    "minY" : 255,
    "maxY" : 420,
    "prop" : {
      "x" : 1283,
      "y" : 261,
      "width" : 123,
      "height" : 37
    },
    "textPosition" : {
      "x" : 1288,
      "y" : 263
    },
    "bgColor" : {
      "r" : 184,
      "g" : 154,
      "b" : 230
    },
    "fgColor" : {
      "r" : 161,
      "g" : 1,
      "b" : 2
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1406,
          "y" : 261
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1406,
          "y" : 261
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 112304,
      "type" : "INHIBITOR",
      "segments" : [ {
        "from" : {
          "x" : 1283,
          "y" : 296
        },
        "to" : {
          "x" : 1292,
          "y" : 296
        }
      }, {
        "from" : {
          "x" : 1292,
          "y" : 296
        },
        "to" : {
          "x" : 1145,
          "y" : 417
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 1142,
          "y" : 414
        },
        "b" : {
          "x" : 1148,
          "y" : 420
        },
        "c" : {
          "x" : 1145,
          "y" : 417
        },
        "type" : "STOP",
        "centre" : {
          "x" : 1145,
          "y" : 417
        }
      }
    } ]
  }, {
    "id" : 112319,
    "reactomeId" : 10648072,
    "displayName" : "Regulation of clotting cascade",
    "schemaClass" : "Pathway",
    "renderableClass" : "ProcessNode",
    "position" : {
      "x" : 482,
      "y" : 121
    },
    "minX" : 395,
    "maxX" : 569,
    "minY" : 86,
    "maxY" : 156,
    "prop" : {
      "x" : 395,
      "y" : 86,
      "width" : 174,
      "height" : 70
    },
    "textPosition" : {
      "x" : 405,
      "y" : 99
    },
    "connectors" : [ ]
  }, {
    "id" : 112221,
    "reactomeId" : 10568041,
    "displayName" : "f3b",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 89,
      "y" : 578
    },
    "minX" : 28,
    "maxX" : 156,
    "minY" : 554,
    "maxY" : 597,
    "prop" : {
      "x" : 28,
      "y" : 560,
      "width" : 122,
      "height" : 37
    },
    "textPosition" : {
      "x" : 75,
      "y" : 568
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 150,
          "y" : 560
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 150,
          "y" : 560
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 112220,
      "type" : "INPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 112222,
    "reactomeId" : 10568011,
    "displayName" : "f3b",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 251,
      "y" : 539
    },
    "minX" : 202,
    "maxX" : 333,
    "minY" : 485,
    "maxY" : 551,
    "prop" : {
      "x" : 202,
      "y" : 528,
      "width" : 99,
      "height" : 23
    },
    "textPosition" : {
      "x" : 237,
      "y" : 529
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 301,
          "y" : 528
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 301,
          "y" : 528
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 112220,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 112223,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 267,
          "y" : 525
        },
        "to" : {
          "x" : 327,
          "y" : 485
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 112241,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 293,
          "y" : 525
        },
        "to" : {
          "x" : 333,
          "y" : 517
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 112225,
    "reactomeId" : 10568053,
    "displayName" : "TF:F7",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 454,
      "y" : 549
    },
    "minX" : 434,
    "maxX" : 515,
    "minY" : 519,
    "maxY" : 561,
    "prop" : {
      "x" : 434,
      "y" : 538,
      "width" : 41,
      "height" : 23
    },
    "textPosition" : {
      "x" : 434,
      "y" : 540
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 475,
          "y" : 538
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 475,
          "y" : 538
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 112223,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 112227,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 470,
          "y" : 535
        },
        "to" : {
          "x" : 498,
          "y" : 519
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 112227,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 478,
          "y" : 543
        },
        "to" : {
          "x" : 499,
          "y" : 536
        }
      }, {
        "from" : {
          "x" : 499,
          "y" : 536
        },
        "to" : {
          "x" : 508,
          "y" : 528
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 511,
          "y" : 526
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 511,
          "y" : 526
        }
      }
    } ]
  }, {
    "id" : 112224,
    "reactomeId" : 10568047,
    "displayName" : "Factor VII:Ca2+",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 224,
      "y" : 308
    },
    "minX" : 175,
    "maxX" : 327,
    "minY" : 291,
    "maxY" : 485,
    "prop" : {
      "x" : 175,
      "y" : 297,
      "width" : 99,
      "height" : 23
    },
    "textPosition" : {
      "x" : 189,
      "y" : 285
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 274,
          "y" : 297
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 274,
          "y" : 297
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 112223,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 230,
          "y" : 323
        },
        "to" : {
          "x" : 327,
          "y" : 485
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 112239,
      "type" : "INPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 112226,
    "reactomeId" : 74112,
    "displayName" : "Ca2+",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 347,
      "y" : 439
    },
    "minX" : 322,
    "maxX" : 429,
    "minY" : 423,
    "maxY" : 510,
    "prop" : {
      "x" : 322,
      "y" : 424,
      "width" : 50,
      "height" : 31
    },
    "textPosition" : {
      "x" : 326,
      "y" : 429
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 367,
          "y" : 429
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 367,
          "y" : 429
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 112223,
      "type" : "ACTIVATOR",
      "segments" : [ {
        "from" : {
          "x" : 358,
          "y" : 458
        },
        "to" : {
          "x" : 376,
          "y" : 479
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 368,
          "y" : 476
        },
        "b" : {
          "x" : 376,
          "y" : 479
        },
        "c" : {
          "x" : 375,
          "y" : 471
        },
        "type" : "ARROW",
        "empty" : true,
        "centre" : {
          "x" : 375,
          "y" : 471
        }
      }
    }, {
      "edgeId" : 112237,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 375,
          "y" : 447
        },
        "to" : {
          "x" : 429,
          "y" : 466
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 112241,
      "type" : "ACTIVATOR",
      "segments" : [ {
        "from" : {
          "x" : 349,
          "y" : 458
        },
        "to" : {
          "x" : 360,
          "y" : 510
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 355,
          "y" : 504
        },
        "b" : {
          "x" : 360,
          "y" : 510
        },
        "c" : {
          "x" : 362,
          "y" : 502
        },
        "type" : "ARROW",
        "empty" : true,
        "centre" : {
          "x" : 362,
          "y" : 502
        }
      }
    } ]
  }, {
    "id" : 112229,
    "reactomeId" : 10642873,
    "displayName" : "TF:FVII:FXa",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 581,
      "y" : 545
    },
    "minX" : 545,
    "maxX" : 642,
    "minY" : 519,
    "maxY" : 557,
    "prop" : {
      "x" : 545,
      "y" : 534,
      "width" : 72,
      "height" : 23
    },
    "textPosition" : {
      "x" : 555,
      "y" : 522
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 617,
          "y" : 534
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 617,
          "y" : 534
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 112227,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 566,
          "y" : 531
        },
        "to" : {
          "x" : 548,
          "y" : 519
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 558,
          "y" : 530
        },
        "b" : {
          "x" : 566,
          "y" : 531
        },
        "c" : {
          "x" : 562,
          "y" : 524
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 562,
          "y" : 524
        }
      }
    }, {
      "edgeId" : 112232,
      "type" : "INPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 112232,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 620,
          "y" : 539
        },
        "to" : {
          "x" : 637,
          "y" : 536
        }
      }, {
        "from" : {
          "x" : 637,
          "y" : 536
        },
        "to" : {
          "x" : 637,
          "y" : 548
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 638,
          "y" : 552
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 638,
          "y" : 552
        }
      }
    } ]
  }, {
    "id" : 112228,
    "reactomeId" : 10568863,
    "displayName" : "factor X",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 350,
      "y" : 357
    },
    "minX" : 323,
    "maxX" : 498,
    "minY" : 340,
    "maxY" : 519,
    "prop" : {
      "x" : 323,
      "y" : 346,
      "width" : 54,
      "height" : 23
    },
    "textPosition" : {
      "x" : 325,
      "y" : 334
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 377,
          "y" : 346
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 377,
          "y" : 346
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 112227,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 360,
          "y" : 372
        },
        "to" : {
          "x" : 498,
          "y" : 519
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 112237,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 358,
          "y" : 372
        },
        "to" : {
          "x" : 429,
          "y" : 466
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 112231,
    "reactomeId" : 947594,
    "displayName" : "APLs",
    "schemaClass" : "DefinedSet",
    "renderableClass" : "EntitySet",
    "position" : {
      "x" : 502,
      "y" : 571
    },
    "minX" : 484,
    "maxX" : 528,
    "minY" : 475,
    "maxY" : 583,
    "prop" : {
      "x" : 484,
      "y" : 560,
      "width" : 36,
      "height" : 23
    },
    "textPosition" : {
      "x" : 487,
      "y" : 554
    },
    "connectors" : [ {
      "edgeId" : 112227,
      "type" : "ACTIVATOR",
      "segments" : [ {
        "from" : {
          "x" : 511,
          "y" : 554
        },
        "to" : {
          "x" : 526,
          "y" : 542
        }
      }, {
        "from" : {
          "x" : 526,
          "y" : 542
        },
        "to" : {
          "x" : 522,
          "y" : 527
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 528,
          "y" : 533
        },
        "b" : {
          "x" : 522,
          "y" : 527
        },
        "c" : {
          "x" : 520,
          "y" : 535
        },
        "type" : "ARROW",
        "empty" : true,
        "centre" : {
          "x" : 520,
          "y" : 535
        }
      }
    }, {
      "edgeId" : 112237,
      "type" : "ACTIVATOR",
      "segments" : [ {
        "from" : {
          "x" : 502,
          "y" : 554
        },
        "to" : {
          "x" : 502,
          "y" : 475
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 506,
          "y" : 482
        },
        "b" : {
          "x" : 502,
          "y" : 475
        },
        "c" : {
          "x" : 498,
          "y" : 482
        },
        "type" : "ARROW",
        "empty" : true,
        "centre" : {
          "x" : 498,
          "y" : 482
        }
      }
    } ]
  }, {
    "id" : 112230,
    "reactomeId" : 10568865,
    "displayName" : "f10",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 614,
      "y" : 409
    },
    "minX" : 545,
    "maxX" : 678,
    "minY" : 385,
    "maxY" : 519,
    "prop" : {
      "x" : 556,
      "y" : 391,
      "width" : 116,
      "height" : 37
    },
    "textPosition" : {
      "x" : 600,
      "y" : 399
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 672,
          "y" : 391
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 672,
          "y" : 391
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 112227,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 602,
          "y" : 431
        },
        "to" : {
          "x" : 548,
          "y" : 519
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 602,
          "y" : 439
        },
        "b" : {
          "x" : 602,
          "y" : 431
        },
        "c" : {
          "x" : 595,
          "y" : 435
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 595,
          "y" : 435
        }
      }
    }, {
      "edgeId" : 112237,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 591,
          "y" : 431
        },
        "to" : {
          "x" : 545,
          "y" : 466
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 588,
          "y" : 438
        },
        "b" : {
          "x" : 591,
          "y" : 431
        },
        "c" : {
          "x" : 583,
          "y" : 432
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 583,
          "y" : 432
        }
      }
    } ]
  }, {
    "id" : 112233,
    "reactomeId" : 10642869,
    "displayName" : "TF:FVIIa:FXa",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 603,
      "y" : 609
    },
    "minX" : 545,
    "maxX" : 676,
    "minY" : 466,
    "maxY" : 621,
    "prop" : {
      "x" : 564,
      "y" : 598,
      "width" : 79,
      "height" : 23
    },
    "textPosition" : {
      "x" : 574,
      "y" : 586
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 643,
          "y" : 598
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 643,
          "y" : 598
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 112232,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 112234,
      "type" : "INPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 112237,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 618,
          "y" : 595
        },
        "to" : {
          "x" : 676,
          "y" : 554
        }
      }, {
        "from" : {
          "x" : 676,
          "y" : 554
        },
        "to" : {
          "x" : 545,
          "y" : 466
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 621,
          "y" : 588
        },
        "b" : {
          "x" : 618,
          "y" : 595
        },
        "c" : {
          "x" : 626,
          "y" : 594
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 626,
          "y" : 594
        }
      }
    } ]
  }, {
    "id" : 112235,
    "reactomeId" : 10567985,
    "displayName" : "factor Xa",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 706,
      "y" : 492
    },
    "minX" : 155,
    "maxX" : 1130,
    "minY" : 284,
    "maxY" : 676,
    "prop" : {
      "x" : 676,
      "y" : 481,
      "width" : 61,
      "height" : 23
    },
    "textPosition" : {
      "x" : 682,
      "y" : 469
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 737,
          "y" : 481
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 737,
          "y" : 481
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 112259,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 712,
          "y" : 507
        },
        "to" : {
          "x" : 767,
          "y" : 593
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 112299,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 709,
          "y" : 507
        },
        "to" : {
          "x" : 736,
          "y" : 602
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 112234,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 702,
          "y" : 507
        },
        "to" : {
          "x" : 653,
          "y" : 676
        }
      }, {
        "from" : {
          "x" : 653,
          "y" : 676
        },
        "to" : {
          "x" : 629,
          "y" : 660
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 704,
          "y" : 515
        },
        "b" : {
          "x" : 702,
          "y" : 507
        },
        "c" : {
          "x" : 696,
          "y" : 513
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 696,
          "y" : 513
        }
      }
    }, {
      "edgeId" : 112239,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 706,
          "y" : 478
        },
        "to" : {
          "x" : 713,
          "y" : 284
        }
      }, {
        "from" : {
          "x" : 713,
          "y" : 284
        },
        "to" : {
          "x" : 155,
          "y" : 284
        }
      }, {
        "from" : {
          "x" : 155,
          "y" : 284
        },
        "to" : {
          "x" : 156,
          "y" : 354
        }
      }, {
        "from" : {
          "x" : 156,
          "y" : 354
        },
        "to" : {
          "x" : 207,
          "y" : 356
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 211,
          "y" : 356
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 211,
          "y" : 356
        }
      }
    }, {
      "edgeId" : 112304,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 715,
          "y" : 507
        },
        "to" : {
          "x" : 804,
          "y" : 607
        }
      }, {
        "from" : {
          "x" : 804,
          "y" : 607
        },
        "to" : {
          "x" : 1086,
          "y" : 607
        }
      }, {
        "from" : {
          "x" : 1086,
          "y" : 607
        },
        "to" : {
          "x" : 1086,
          "y" : 423
        }
      }, {
        "from" : {
          "x" : 1086,
          "y" : 423
        },
        "to" : {
          "x" : 1122,
          "y" : 423
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 1126,
          "y" : 423
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1126,
          "y" : 423
        }
      }
    }, {
      "edgeId" : 112249,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 710,
          "y" : 478
        },
        "to" : {
          "x" : 783,
          "y" : 299
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 784,
          "y" : 295
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 784,
          "y" : 295
        }
      }
    } ]
  }, {
    "id" : 112236,
    "reactomeId" : 10568037,
    "displayName" : "TF:FVIIa",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 604,
      "y" : 690
    },
    "minX" : 577,
    "maxX" : 637,
    "minY" : 660,
    "maxY" : 702,
    "prop" : {
      "x" : 577,
      "y" : 679,
      "width" : 54,
      "height" : 23
    },
    "textPosition" : {
      "x" : 585,
      "y" : 667
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 631,
          "y" : 679
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 631,
          "y" : 679
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 112234,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 613,
          "y" : 676
        },
        "to" : {
          "x" : 629,
          "y" : 660
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 615,
          "y" : 668
        },
        "b" : {
          "x" : 613,
          "y" : 676
        },
        "c" : {
          "x" : 621,
          "y" : 674
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 621,
          "y" : 674
        }
      }
    } ]
  }, {
    "id" : 112238,
    "reactomeId" : 10568037,
    "displayName" : "TF:FVIIa",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 380,
      "y" : 554
    },
    "minX" : 181,
    "maxX" : 503,
    "minY" : 466,
    "maxY" : 897,
    "prop" : {
      "x" : 353,
      "y" : 543,
      "width" : 54,
      "height" : 23
    },
    "textPosition" : {
      "x" : 361,
      "y" : 531
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 407,
          "y" : 543
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 407,
          "y" : 543
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 112237,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 386,
          "y" : 540
        },
        "to" : {
          "x" : 429,
          "y" : 466
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 112237,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 400,
          "y" : 540
        },
        "to" : {
          "x" : 496,
          "y" : 488
        }
      }, {
        "from" : {
          "x" : 496,
          "y" : 488
        },
        "to" : {
          "x" : 498,
          "y" : 481
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 499,
          "y" : 478
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 499,
          "y" : 478
        }
      }
    }, {
      "edgeId" : 112241,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 112242,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 373,
          "y" : 569
        },
        "to" : {
          "x" : 181,
          "y" : 884
        }
      }, {
        "from" : {
          "x" : 181,
          "y" : 884
        },
        "to" : {
          "x" : 187,
          "y" : 897
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 112242,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 374,
          "y" : 569
        },
        "to" : {
          "x" : 213,
          "y" : 875
        }
      }, {
        "from" : {
          "x" : 213,
          "y" : 875
        },
        "to" : {
          "x" : 213,
          "y" : 881
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 213,
          "y" : 885
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 213,
          "y" : 885
        }
      }
    }, {
      "edgeId" : 112247,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 380,
          "y" : 569
        },
        "to" : {
          "x" : 404,
          "y" : 871
        }
      }, {
        "from" : {
          "x" : 404,
          "y" : 871
        },
        "to" : {
          "x" : 370,
          "y" : 896
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 385,
          "y" : 576
        },
        "b" : {
          "x" : 380,
          "y" : 569
        },
        "c" : {
          "x" : 377,
          "y" : 576
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 377,
          "y" : 576
        }
      }
    } ]
  }, {
    "id" : 112240,
    "reactomeId" : 10568029,
    "displayName" : "factor VIIa:Ca2+",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 224,
      "y" : 439
    },
    "minX" : 172,
    "maxX" : 333,
    "minY" : 422,
    "maxY" : 517,
    "prop" : {
      "x" : 172,
      "y" : 428,
      "width" : 104,
      "height" : 23
    },
    "textPosition" : {
      "x" : 186,
      "y" : 416
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 276,
          "y" : 428
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 276,
          "y" : 428
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 112239,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 112241,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 240,
          "y" : 454
        },
        "to" : {
          "x" : 333,
          "y" : 517
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 112243,
    "reactomeId" : 10568882,
    "displayName" : "f9b",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 103,
      "y" : 944
    },
    "minX" : 50,
    "maxX" : 187,
    "minY" : 897,
    "maxY" : 963,
    "prop" : {
      "x" : 50,
      "y" : 926,
      "width" : 107,
      "height" : 37
    },
    "textPosition" : {
      "x" : 89,
      "y" : 934
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 157,
          "y" : 926
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 157,
          "y" : 926
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 112269,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 112242,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 136,
          "y" : 923
        },
        "to" : {
          "x" : 187,
          "y" : 897
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 112245,
    "reactomeId" : 10645866,
    "displayName" : "TF:FVIIa:FIXa",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 300,
      "y" : 868
    },
    "minX" : 236,
    "maxX" : 347,
    "minY" : 851,
    "maxY" : 897,
    "prop" : {
      "x" : 259,
      "y" : 857,
      "width" : 82,
      "height" : 23
    },
    "textPosition" : {
      "x" : 270,
      "y" : 845
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 341,
          "y" : 857
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 341,
          "y" : 857
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 112242,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 274,
          "y" : 883
        },
        "to" : {
          "x" : 236,
          "y" : 897
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 269,
          "y" : 889
        },
        "b" : {
          "x" : 274,
          "y" : 883
        },
        "c" : {
          "x" : 266,
          "y" : 882
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 266,
          "y" : 882
        }
      }
    }, {
      "edgeId" : 112247,
      "type" : "INPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 112244,
    "reactomeId" : 10568892,
    "displayName" : "f9b",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 341,
      "y" : 954
    },
    "minX" : 236,
    "maxX" : 407,
    "minY" : 897,
    "maxY" : 973,
    "prop" : {
      "x" : 282,
      "y" : 936,
      "width" : 119,
      "height" : 37
    },
    "textPosition" : {
      "x" : 327,
      "y" : 944
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 401,
          "y" : 936
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 401,
          "y" : 936
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 112242,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 306,
          "y" : 933
        },
        "to" : {
          "x" : 236,
          "y" : 897
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 298,
          "y" : 933
        },
        "b" : {
          "x" : 306,
          "y" : 933
        },
        "c" : {
          "x" : 302,
          "y" : 926
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 302,
          "y" : 926
        }
      }
    } ]
  }, {
    "id" : 112246,
    "reactomeId" : 74112,
    "displayName" : "Ca2+",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 214,
      "y" : 946
    },
    "minX" : 189,
    "maxX" : 240,
    "minY" : 906,
    "maxY" : 962,
    "prop" : {
      "x" : 189,
      "y" : 931,
      "width" : 50,
      "height" : 31
    },
    "textPosition" : {
      "x" : 193,
      "y" : 936
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 234,
          "y" : 936
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 234,
          "y" : 936
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 112242,
      "type" : "ACTIVATOR",
      "segments" : [ {
        "from" : {
          "x" : 213,
          "y" : 928
        },
        "to" : {
          "x" : 213,
          "y" : 906
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 217,
          "y" : 913
        },
        "b" : {
          "x" : 213,
          "y" : 906
        },
        "c" : {
          "x" : 209,
          "y" : 913
        },
        "type" : "ARROW",
        "empty" : true,
        "centre" : {
          "x" : 209,
          "y" : 913
        }
      }
    } ]
  }, {
    "id" : 112248,
    "reactomeId" : 10568890,
    "displayName" : "factor IXa",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 671,
      "y" : 1160
    },
    "minX" : 370,
    "maxX" : 709,
    "minY" : 896,
    "maxY" : 1172,
    "prop" : {
      "x" : 639,
      "y" : 1149,
      "width" : 64,
      "height" : 23
    },
    "textPosition" : {
      "x" : 646,
      "y" : 1137
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 703,
          "y" : 1149
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 703,
          "y" : 1149
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 112271,
      "type" : "INPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 112247,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 657,
          "y" : 1146
        },
        "to" : {
          "x" : 370,
          "y" : 896
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 649,
          "y" : 1144
        },
        "b" : {
          "x" : 657,
          "y" : 1146
        },
        "c" : {
          "x" : 654,
          "y" : 1138
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 654,
          "y" : 1138
        }
      }
    } ]
  }, {
    "id" : 112251,
    "reactomeId" : 10642096,
    "displayName" : "f5",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 906,
      "y" : 374
    },
    "minX" : 789,
    "maxX" : 977,
    "minY" : 317,
    "maxY" : 386,
    "prop" : {
      "x" : 842,
      "y" : 363,
      "width" : 129,
      "height" : 23
    },
    "textPosition" : {
      "x" : 896,
      "y" : 364
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 971,
          "y" : 363
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 971,
          "y" : 363
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 112249,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 881,
          "y" : 360
        },
        "to" : {
          "x" : 789,
          "y" : 319
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 873,
          "y" : 361
        },
        "b" : {
          "x" : 881,
          "y" : 360
        },
        "c" : {
          "x" : 876,
          "y" : 354
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 876,
          "y" : 354
        }
      }
    }, {
      "edgeId" : 112254,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 887,
          "y" : 360
        },
        "to" : {
          "x" : 815,
          "y" : 317
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 879,
          "y" : 360
        },
        "b" : {
          "x" : 887,
          "y" : 360
        },
        "c" : {
          "x" : 883,
          "y" : 353
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 883,
          "y" : 353
        }
      }
    } ]
  }, {
    "id" : 112250,
    "reactomeId" : 10567995,
    "displayName" : "f5",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 800,
      "y" : 217
    },
    "minX" : 773,
    "maxX" : 833,
    "minY" : 200,
    "maxY" : 229,
    "prop" : {
      "x" : 773,
      "y" : 206,
      "width" : 54,
      "height" : 23
    },
    "textPosition" : {
      "x" : 790,
      "y" : 207
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 827,
          "y" : 206
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 827,
          "y" : 206
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 112301,
      "type" : "INPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 112249,
      "type" : "INPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 112254,
      "type" : "INPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 112253,
    "reactomeId" : 10642098,
    "displayName" : "FXa:SERPINC1:HS",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 660,
      "y" : 195
    },
    "minX" : 606,
    "maxX" : 783,
    "minY" : 178,
    "maxY" : 282,
    "prop" : {
      "x" : 606,
      "y" : 184,
      "width" : 109,
      "height" : 23
    },
    "textPosition" : {
      "x" : 611,
      "y" : 172
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 715,
          "y" : 184
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 715,
          "y" : 184
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 112249,
      "type" : "INHIBITOR",
      "segments" : [ {
        "from" : {
          "x" : 676,
          "y" : 210
        },
        "to" : {
          "x" : 781,
          "y" : 279
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 779,
          "y" : 282
        },
        "b" : {
          "x" : 783,
          "y" : 276
        },
        "c" : {
          "x" : 781,
          "y" : 279
        },
        "type" : "STOP",
        "centre" : {
          "x" : 781,
          "y" : 279
        }
      }
    } ]
  }, {
    "id" : 112252,
    "reactomeId" : 10642094,
    "displayName" : "factor Va intermediate",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 810,
      "y" : 414
    },
    "minX" : 736,
    "maxX" : 857,
    "minY" : 317,
    "maxY" : 602,
    "prop" : {
      "x" : 769,
      "y" : 396,
      "width" : 82,
      "height" : 37
    },
    "textPosition" : {
      "x" : 770,
      "y" : 384
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 851,
          "y" : 396
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 851,
          "y" : 396
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 112256,
      "type" : "INPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 112299,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 802,
          "y" : 436
        },
        "to" : {
          "x" : 736,
          "y" : 602
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 112249,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 805,
          "y" : 393
        },
        "to" : {
          "x" : 789,
          "y" : 319
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 800,
          "y" : 387
        },
        "b" : {
          "x" : 805,
          "y" : 393
        },
        "c" : {
          "x" : 807,
          "y" : 385
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 807,
          "y" : 385
        }
      }
    }, {
      "edgeId" : 112254,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 810,
          "y" : 393
        },
        "to" : {
          "x" : 815,
          "y" : 317
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 806,
          "y" : 386
        },
        "b" : {
          "x" : 810,
          "y" : 393
        },
        "c" : {
          "x" : 814,
          "y" : 386
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 814,
          "y" : 386
        }
      }
    } ]
  }, {
    "id" : 112255,
    "reactomeId" : 10567668,
    "displayName" : "activated thrombin (factor IIa)",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 1071,
      "y" : 233
    },
    "minX" : 814,
    "maxX" : 1932,
    "minY" : 98,
    "maxY" : 465,
    "prop" : {
      "x" : 1011,
      "y" : 215,
      "width" : 121,
      "height" : 37
    },
    "textPosition" : {
      "x" : 1014,
      "y" : 203
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1132,
          "y" : 215
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1132,
          "y" : 215
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 112256,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 1068,
          "y" : 255
        },
        "to" : {
          "x" : 1047,
          "y" : 451
        }
      }, {
        "from" : {
          "x" : 1047,
          "y" : 451
        },
        "to" : {
          "x" : 826,
          "y" : 450
        }
      }, {
        "from" : {
          "x" : 826,
          "y" : 450
        },
        "to" : {
          "x" : 820,
          "y" : 458
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 818,
          "y" : 461
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 818,
          "y" : 461
        }
      }
    }, {
      "edgeId" : 112261,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 1082,
          "y" : 255
        },
        "to" : {
          "x" : 1162,
          "y" : 380
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 1089,
          "y" : 259
        },
        "b" : {
          "x" : 1082,
          "y" : 255
        },
        "c" : {
          "x" : 1082,
          "y" : 263
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 1082,
          "y" : 263
        }
      }
    }, {
      "edgeId" : 112273,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 1115,
          "y" : 212
        },
        "to" : {
          "x" : 1181,
          "y" : 187
        }
      }, {
        "from" : {
          "x" : 1181,
          "y" : 187
        },
        "to" : {
          "x" : 1751,
          "y" : 188
        }
      }, {
        "from" : {
          "x" : 1751,
          "y" : 188
        },
        "to" : {
          "x" : 1863,
          "y" : 293
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 1866,
          "y" : 296
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1866,
          "y" : 296
        }
      }
    }, {
      "edgeId" : 112282,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 1068,
          "y" : 212
        },
        "to" : {
          "x" : 1055,
          "y" : 102
        }
      }, {
        "from" : {
          "x" : 1055,
          "y" : 102
        },
        "to" : {
          "x" : 1911,
          "y" : 98
        }
      }, {
        "from" : {
          "x" : 1911,
          "y" : 98
        },
        "to" : {
          "x" : 1926,
          "y" : 115
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 1928,
          "y" : 118
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1928,
          "y" : 118
        }
      }
    }, {
      "edgeId" : 112301,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 1061,
          "y" : 212
        },
        "to" : {
          "x" : 1021,
          "y" : 140
        }
      }, {
        "from" : {
          "x" : 1021,
          "y" : 140
        },
        "to" : {
          "x" : 901,
          "y" : 141
        }
      }, {
        "from" : {
          "x" : 901,
          "y" : 141
        },
        "to" : {
          "x" : 860,
          "y" : 203
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 858,
          "y" : 206
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 858,
          "y" : 206
        }
      }
    }, {
      "edgeId" : 112304,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 1080,
          "y" : 255
        },
        "to" : {
          "x" : 1139,
          "y" : 369
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 1087,
          "y" : 259
        },
        "b" : {
          "x" : 1080,
          "y" : 255
        },
        "c" : {
          "x" : 1080,
          "y" : 263
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 1080,
          "y" : 263
        }
      }
    }, {
      "edgeId" : 112254,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 1008,
          "y" : 231
        },
        "to" : {
          "x" : 983,
          "y" : 231
        }
      }, {
        "from" : {
          "x" : 983,
          "y" : 231
        },
        "to" : {
          "x" : 830,
          "y" : 279
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 826,
          "y" : 280
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 826,
          "y" : 280
        }
      }
    } ]
  } ],
  "edges" : [ {
    "id" : 112256,
    "reactomeId" : 10646008,
    "displayName" : "factor Va intermediate  -> factor Va",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 811,
      "y" : 471
    },
    "minX" : 805,
    "maxX" : 817,
    "minY" : 436,
    "maxY" : 490,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 810,
        "y" : 436
      },
      "to" : {
        "x" : 811,
        "y" : 471
      }
    }, {
      "from" : {
        "x" : 811,
        "y" : 471
      },
      "to" : {
        "x" : 811,
        "y" : 490
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 805,
        "y" : 465
      },
      "b" : {
        "x" : 817,
        "y" : 477
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 811,
        "y" : 471
      }
    },
    "inputs" : [ {
      "id" : 112252
    } ],
    "outputs" : [ {
      "id" : 112257,
      "points" : [ {
        "x" : 859,
        "y" : 500
      } ]
    }, {
      "id" : 112258,
      "points" : [ {
        "x" : 812,
        "y" : 514
      } ]
    } ],
    "catalysts" : [ {
      "id" : 112255,
      "points" : [ {
        "x" : 1068,
        "y" : 255
      }, {
        "x" : 1047,
        "y" : 451
      }, {
        "x" : 826,
        "y" : 450
      } ]
    } ]
  }, {
    "id" : 112259,
    "reactomeId" : 10567993,
    "displayName" : "factor Va + factor Xa -> Va:Xa complex (prothrombinase)",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 768,
      "y" : 631
    },
    "minX" : 762,
    "maxX" : 1235,
    "minY" : 593,
    "maxY" : 637,
    "reactionType" : "binding",
    "segments" : [ {
      "from" : {
        "x" : 767,
        "y" : 593
      },
      "to" : {
        "x" : 768,
        "y" : 631
      }
    }, {
      "from" : {
        "x" : 768,
        "y" : 631
      },
      "to" : {
        "x" : 1235,
        "y" : 634
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 1228,
        "y" : 638
      },
      "b" : {
        "x" : 1235,
        "y" : 634
      },
      "c" : {
        "x" : 1228,
        "y" : 630
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 1228,
        "y" : 630
      }
    },
    "reactionShape" : {
      "c" : {
        "x" : 768,
        "y" : 631
      },
      "r" : 5,
      "type" : "CIRCLE",
      "centre" : {
        "x" : 768,
        "y" : 631
      }
    },
    "inputs" : [ {
      "id" : 112235,
      "points" : [ {
        "x" : 712,
        "y" : 507
      } ]
    }, {
      "id" : 112258,
      "points" : [ {
        "x" : 804,
        "y" : 543
      } ]
    } ],
    "outputs" : [ {
      "id" : 112260
    } ]
  }, {
    "id" : 112261,
    "reactomeId" : 10567978,
    "displayName" : "prothrombin -> activated thrombin (factor IIa) + thrombin activation peptide (prothrombinase catalyst)",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 1162,
      "y" : 422
    },
    "minX" : 1153,
    "maxX" : 1168,
    "minY" : 380,
    "maxY" : 493,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 1153,
        "y" : 493
      },
      "to" : {
        "x" : 1162,
        "y" : 422
      }
    }, {
      "from" : {
        "x" : 1162,
        "y" : 422
      },
      "to" : {
        "x" : 1162,
        "y" : 380
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 1156,
        "y" : 416
      },
      "b" : {
        "x" : 1168,
        "y" : 428
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 1162,
        "y" : 422
      }
    },
    "inputs" : [ {
      "id" : 112262
    } ],
    "outputs" : [ {
      "id" : 112255,
      "points" : [ {
        "x" : 1082,
        "y" : 255
      } ]
    }, {
      "id" : 112263,
      "points" : [ {
        "x" : 1189,
        "y" : 312
      } ]
    } ],
    "catalysts" : [ {
      "id" : 112260,
      "points" : [ {
        "x" : 1261,
        "y" : 621
      }, {
        "x" : 1204,
        "y" : 441
      } ]
    } ],
    "inhibitors" : [ {
      "id" : 112264,
      "points" : [ {
        "x" : 1306,
        "y" : 357
      } ]
    } ]
  }, {
    "id" : 112265,
    "reactomeId" : 10644632,
    "displayName" : "ANO6 exposes PS, PE on the platelet membrane",
    "schemaClass" : "BlackBoxEvent",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 1315,
      "y" : 378
    },
    "minX" : 1309,
    "maxX" : 1416,
    "minY" : 372,
    "maxY" : 404,
    "reactionType" : "omitted",
    "segments" : [ {
      "from" : {
        "x" : 1355,
        "y" : 404
      },
      "to" : {
        "x" : 1315,
        "y" : 378
      }
    }, {
      "from" : {
        "x" : 1315,
        "y" : 378
      },
      "to" : {
        "x" : 1416,
        "y" : 380
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 1409,
        "y" : 384
      },
      "b" : {
        "x" : 1416,
        "y" : 380
      },
      "c" : {
        "x" : 1409,
        "y" : 376
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 1409,
        "y" : 376
      }
    },
    "reactionShape" : {
      "a" : {
        "x" : 1309,
        "y" : 372
      },
      "b" : {
        "x" : 1321,
        "y" : 384
      },
      "s" : "\\\\",
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 1315,
        "y" : 378
      }
    },
    "inputs" : [ {
      "id" : 112266
    } ],
    "outputs" : [ {
      "id" : 112267
    } ],
    "catalysts" : [ {
      "id" : 112268,
      "points" : [ {
        "x" : 1276,
        "y" : 416
      }, {
        "x" : 1294,
        "y" : 374
      } ]
    } ]
  }, {
    "id" : 112269,
    "reactomeId" : 10640128,
    "displayName" : "FIX is secreted",
    "schemaClass" : "BlackBoxEvent",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 175,
      "y" : 1028
    },
    "minX" : 118,
    "maxX" : 181,
    "minY" : 966,
    "maxY" : 1098,
    "reactionType" : "omitted",
    "segments" : [ {
      "from" : {
        "x" : 174,
        "y" : 1098
      },
      "to" : {
        "x" : 175,
        "y" : 1028
      }
    }, {
      "from" : {
        "x" : 175,
        "y" : 1028
      },
      "to" : {
        "x" : 118,
        "y" : 966
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 126,
        "y" : 968
      },
      "b" : {
        "x" : 118,
        "y" : 966
      },
      "c" : {
        "x" : 120,
        "y" : 974
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 120,
        "y" : 974
      }
    },
    "reactionShape" : {
      "a" : {
        "x" : 169,
        "y" : 1022
      },
      "b" : {
        "x" : 181,
        "y" : 1034
      },
      "s" : "\\\\",
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 175,
        "y" : 1028
      }
    },
    "inputs" : [ {
      "id" : 112270
    } ],
    "outputs" : [ {
      "id" : 112243
    } ]
  }, {
    "id" : 112271,
    "reactomeId" : 10612915,
    "displayName" : "factor IXa associates with cell membrane",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 1459,
      "y" : 1134
    },
    "minX" : 706,
    "maxX" : 1612,
    "minY" : 1049,
    "maxY" : 1158,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 706,
        "y" : 1158
      },
      "to" : {
        "x" : 1459,
        "y" : 1134
      }
    }, {
      "from" : {
        "x" : 1459,
        "y" : 1134
      },
      "to" : {
        "x" : 1612,
        "y" : 1049
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 1608,
        "y" : 1056
      },
      "b" : {
        "x" : 1612,
        "y" : 1049
      },
      "c" : {
        "x" : 1604,
        "y" : 1049
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 1604,
        "y" : 1049
      }
    },
    "reactionShape" : {
      "a" : {
        "x" : 1453,
        "y" : 1128
      },
      "b" : {
        "x" : 1465,
        "y" : 1140
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 1459,
        "y" : 1134
      }
    },
    "inputs" : [ {
      "id" : 112248
    } ],
    "outputs" : [ {
      "id" : 112272
    } ]
  }, {
    "id" : 112273,
    "reactomeId" : 10568254,
    "displayName" : "fibrinogen -> fibrin monomer + 2 fibrinopeptide A + 2 fibrinopeptide B",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 1875,
      "y" : 304
    },
    "minX" : 1846,
    "maxX" : 1904,
    "minY" : 298,
    "maxY" : 310,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 1846,
        "y" : 304
      },
      "to" : {
        "x" : 1875,
        "y" : 304
      }
    }, {
      "from" : {
        "x" : 1875,
        "y" : 304
      },
      "to" : {
        "x" : 1904,
        "y" : 304
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 1869,
        "y" : 298
      },
      "b" : {
        "x" : 1881,
        "y" : 310
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 1875,
        "y" : 304
      }
    },
    "inputs" : [ {
      "id" : 112274
    } ],
    "outputs" : [ {
      "id" : 112275,
      "points" : [ {
        "x" : 1955,
        "y" : 305
      } ]
    }, {
      "id" : 112276,
      "points" : [ {
        "x" : 1897,
        "y" : 339
      } ],
      "stoichiometry" : 2
    }, {
      "id" : 112277,
      "points" : [ {
        "x" : 1973,
        "y" : 336
      } ],
      "stoichiometry" : 2
    } ],
    "catalysts" : [ {
      "id" : 112255,
      "points" : [ {
        "x" : 1115,
        "y" : 212
      }, {
        "x" : 1181,
        "y" : 187
      }, {
        "x" : 1751,
        "y" : 188
      } ]
    } ],
    "inhibitors" : [ {
      "id" : 112278,
      "points" : [ {
        "x" : 1923,
        "y" : 284
      } ]
    }, {
      "id" : 112279,
      "points" : [ {
        "x" : 1867,
        "y" : 217
      } ]
    } ]
  }, {
    "id" : 112280,
    "reactomeId" : 10568256,
    "displayName" : "n fibrin monomers -> fibrin multimer",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 2096,
      "y" : 304
    },
    "minX" : 2059,
    "maxX" : 2124,
    "minY" : 298,
    "maxY" : 310,
    "reactionType" : "binding",
    "segments" : [ {
      "from" : {
        "x" : 2059,
        "y" : 304
      },
      "to" : {
        "x" : 2096,
        "y" : 304
      }
    }, {
      "from" : {
        "x" : 2096,
        "y" : 304
      },
      "to" : {
        "x" : 2124,
        "y" : 304
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 2117,
        "y" : 308
      },
      "b" : {
        "x" : 2124,
        "y" : 304
      },
      "c" : {
        "x" : 2117,
        "y" : 300
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 2117,
        "y" : 300
      }
    },
    "reactionShape" : {
      "c" : {
        "x" : 2096,
        "y" : 304
      },
      "r" : 5,
      "type" : "CIRCLE",
      "centre" : {
        "x" : 2096,
        "y" : 304
      }
    },
    "inputs" : [ {
      "id" : 112275,
      "stoichiometry" : 3
    } ],
    "outputs" : [ {
      "id" : 112281
    } ]
  }, {
    "id" : 112282,
    "reactomeId" : 10567925,
    "displayName" : "factor XIII -> factor XIII cleaved tetramer + 2 factor XIII A activation peptides",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 1936,
      "y" : 127
    },
    "minX" : 1840,
    "maxX" : 1972,
    "minY" : 121,
    "maxY" : 133,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 1840,
        "y" : 129
      },
      "to" : {
        "x" : 1936,
        "y" : 127
      }
    }, {
      "from" : {
        "x" : 1936,
        "y" : 127
      },
      "to" : {
        "x" : 1972,
        "y" : 128
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 1930,
        "y" : 121
      },
      "b" : {
        "x" : 1942,
        "y" : 133
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 1936,
        "y" : 127
      }
    },
    "inputs" : [ {
      "id" : 112283
    } ],
    "outputs" : [ {
      "id" : 112284,
      "points" : [ {
        "x" : 1998,
        "y" : 98
      } ],
      "stoichiometry" : 2
    }, {
      "id" : 112285,
      "points" : [ {
        "x" : 2019,
        "y" : 129
      } ]
    } ],
    "catalysts" : [ {
      "id" : 112255,
      "points" : [ {
        "x" : 1068,
        "y" : 212
      }, {
        "x" : 1055,
        "y" : 102
      }, {
        "x" : 1911,
        "y" : 98
      } ]
    } ],
    "inhibitors" : [ {
      "id" : 112286,
      "points" : [ {
        "x" : 2322,
        "y" : 679
      }, {
        "x" : 2456,
        "y" : 673
      }, {
        "x" : 2455,
        "y" : 37
      }, {
        "x" : 1935,
        "y" : 37
      } ]
    }, {
      "id" : 112278,
      "points" : [ {
        "x" : 1965,
        "y" : 235
      }, {
        "x" : 1985,
        "y" : 195
      } ]
    }, {
      "id" : 112279,
      "points" : [ {
        "x" : 1896,
        "y" : 154
      } ]
    } ],
    "activators" : [ {
      "id" : 112281,
      "points" : [ {
        "x" : 2158,
        "y" : 292
      } ]
    } ]
  }, {
    "id" : 112220,
    "reactomeId" : 10568043,
    "displayName" : "sequestered tissue factor -> tissue factor",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 155,
      "y" : 532
    },
    "minX" : 115,
    "maxX" : 199,
    "minY" : 526,
    "maxY" : 557,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 115,
        "y" : 557
      },
      "to" : {
        "x" : 155,
        "y" : 532
      }
    }, {
      "from" : {
        "x" : 155,
        "y" : 532
      },
      "to" : {
        "x" : 199,
        "y" : 535
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 192,
        "y" : 539
      },
      "b" : {
        "x" : 199,
        "y" : 535
      },
      "c" : {
        "x" : 192,
        "y" : 531
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 192,
        "y" : 531
      }
    },
    "reactionShape" : {
      "a" : {
        "x" : 149,
        "y" : 526
      },
      "b" : {
        "x" : 161,
        "y" : 538
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 155,
        "y" : 532
      }
    },
    "inputs" : [ {
      "id" : 112221
    } ],
    "outputs" : [ {
      "id" : 112222
    } ]
  }, {
    "id" : 112223,
    "reactomeId" : 10568055,
    "displayName" : "tissue factor (TF) + factor VII (F7) -> TF:F7 complex",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 382,
      "y" : 486
    },
    "minX" : 327,
    "maxX" : 440,
    "minY" : 480,
    "maxY" : 535,
    "reactionType" : "binding",
    "segments" : [ {
      "from" : {
        "x" : 327,
        "y" : 485
      },
      "to" : {
        "x" : 382,
        "y" : 486
      }
    }, {
      "from" : {
        "x" : 382,
        "y" : 486
      },
      "to" : {
        "x" : 440,
        "y" : 535
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 432,
        "y" : 534
      },
      "b" : {
        "x" : 440,
        "y" : 535
      },
      "c" : {
        "x" : 437,
        "y" : 527
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 437,
        "y" : 527
      }
    },
    "reactionShape" : {
      "c" : {
        "x" : 382,
        "y" : 486
      },
      "r" : 5,
      "type" : "CIRCLE",
      "centre" : {
        "x" : 382,
        "y" : 486
      }
    },
    "inputs" : [ {
      "id" : 112224,
      "points" : [ {
        "x" : 230,
        "y" : 323
      } ]
    }, {
      "id" : 112222,
      "points" : [ {
        "x" : 267,
        "y" : 525
      } ]
    } ],
    "outputs" : [ {
      "id" : 112225
    } ],
    "activators" : [ {
      "id" : 112226,
      "points" : [ {
        "x" : 358,
        "y" : 458
      } ]
    } ]
  }, {
    "id" : 112287,
    "reactomeId" : 10568260,
    "displayName" : "factor XIII cleaved tetramer + 2 Ca++ -> factor XIIIa + 2 factor XIII B chain",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 2186,
      "y" : 129
    },
    "minX" : 2163,
    "maxX" : 2212,
    "minY" : 123,
    "maxY" : 135,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 2163,
        "y" : 129
      },
      "to" : {
        "x" : 2186,
        "y" : 129
      }
    }, {
      "from" : {
        "x" : 2186,
        "y" : 129
      },
      "to" : {
        "x" : 2212,
        "y" : 130
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 2180,
        "y" : 123
      },
      "b" : {
        "x" : 2192,
        "y" : 135
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 2186,
        "y" : 129
      }
    },
    "inputs" : [ {
      "id" : 112285,
      "points" : [ {
        "x" : 2140,
        "y" : 129
      } ]
    }, {
      "id" : 112288,
      "points" : [ {
        "x" : 2155,
        "y" : 104
      } ],
      "stoichiometry" : 2
    } ],
    "outputs" : [ {
      "id" : 112289,
      "points" : [ {
        "x" : 2254,
        "y" : 174
      } ]
    }, {
      "id" : 112290,
      "points" : [ {
        "x" : 2227,
        "y" : 94
      } ],
      "stoichiometry" : 2
    } ]
  }, {
    "id" : 112227,
    "reactomeId" : 10642876,
    "displayName" : "TF:FVII+FX -> TF:FVII:FXa + FX activation peptide (TF:F7 catalyst)",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 520,
      "y" : 518
    },
    "minX" : 498,
    "maxX" : 548,
    "minY" : 512,
    "maxY" : 524,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 498,
        "y" : 519
      },
      "to" : {
        "x" : 520,
        "y" : 518
      }
    }, {
      "from" : {
        "x" : 520,
        "y" : 518
      },
      "to" : {
        "x" : 548,
        "y" : 519
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 514,
        "y" : 512
      },
      "b" : {
        "x" : 526,
        "y" : 524
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 520,
        "y" : 518
      }
    },
    "inputs" : [ {
      "id" : 112225,
      "points" : [ {
        "x" : 470,
        "y" : 535
      } ]
    }, {
      "id" : 112228,
      "points" : [ {
        "x" : 360,
        "y" : 372
      } ]
    } ],
    "outputs" : [ {
      "id" : 112229,
      "points" : [ {
        "x" : 566,
        "y" : 531
      } ]
    }, {
      "id" : 112230,
      "points" : [ {
        "x" : 602,
        "y" : 431
      } ]
    } ],
    "catalysts" : [ {
      "id" : 112225,
      "points" : [ {
        "x" : 478,
        "y" : 543
      }, {
        "x" : 499,
        "y" : 536
      } ]
    } ],
    "activators" : [ {
      "id" : 112231,
      "points" : [ {
        "x" : 511,
        "y" : 554
      }, {
        "x" : 526,
        "y" : 542
      } ]
    } ]
  }, {
    "id" : 112291,
    "reactomeId" : 10567627,
    "displayName" : "Adhesion of integrin αIIbβ3 to fibrin network",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 2209,
      "y" : 363
    },
    "minX" : 2183,
    "maxX" : 2227,
    "minY" : 357,
    "maxY" : 378,
    "reactionType" : "binding",
    "segments" : [ {
      "from" : {
        "x" : 2183,
        "y" : 362
      },
      "to" : {
        "x" : 2209,
        "y" : 363
      }
    }, {
      "from" : {
        "x" : 2209,
        "y" : 363
      },
      "to" : {
        "x" : 2227,
        "y" : 378
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 2219,
        "y" : 377
      },
      "b" : {
        "x" : 2227,
        "y" : 378
      },
      "c" : {
        "x" : 2224,
        "y" : 370
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 2224,
        "y" : 370
      }
    },
    "reactionShape" : {
      "c" : {
        "x" : 2209,
        "y" : 363
      },
      "r" : 5,
      "type" : "CIRCLE",
      "centre" : {
        "x" : 2209,
        "y" : 363
      }
    },
    "inputs" : [ {
      "id" : 112292,
      "points" : [ {
        "x" : 2157,
        "y" : 369
      } ]
    }, {
      "id" : 112281,
      "points" : [ {
        "x" : 2175,
        "y" : 321
      } ]
    } ],
    "outputs" : [ {
      "id" : 112293
    } ]
  }, {
    "id" : 112294,
    "reactomeId" : 10568263,
    "displayName" : "fibrin multimer -> fibrin multimer, crosslinked + NH4+",
    "schemaClass" : "BlackBoxEvent",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 2281,
      "y" : 304
    },
    "minX" : 2224,
    "maxX" : 2306,
    "minY" : 298,
    "maxY" : 310,
    "reactionType" : "omitted",
    "segments" : [ {
      "from" : {
        "x" : 2224,
        "y" : 305
      },
      "to" : {
        "x" : 2281,
        "y" : 304
      }
    }, {
      "from" : {
        "x" : 2281,
        "y" : 304
      },
      "to" : {
        "x" : 2306,
        "y" : 304
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 2275,
        "y" : 298
      },
      "b" : {
        "x" : 2287,
        "y" : 310
      },
      "s" : "\\\\",
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 2281,
        "y" : 304
      }
    },
    "inputs" : [ {
      "id" : 112281
    } ],
    "outputs" : [ {
      "id" : 112295,
      "points" : [ {
        "x" : 2350,
        "y" : 287
      } ]
    }, {
      "id" : 112296,
      "points" : [ {
        "x" : 2374,
        "y" : 364
      } ]
    } ],
    "catalysts" : [ {
      "id" : 112289,
      "points" : [ {
        "x" : 2266,
        "y" : 203
      } ]
    } ]
  }, {
    "id" : 112297,
    "reactomeId" : 10645805,
    "displayName" : "αIIbβ3:fibrin multimer ->αIIbβ3:fibrin multimer, crosslinked + NH4+",
    "schemaClass" : "BlackBoxEvent",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 2266,
      "y" : 356
    },
    "minX" : 2260,
    "maxX" : 2319,
    "minY" : 350,
    "maxY" : 378,
    "reactionType" : "omitted",
    "segments" : [ {
      "from" : {
        "x" : 2260,
        "y" : 378
      },
      "to" : {
        "x" : 2266,
        "y" : 356
      }
    }, {
      "from" : {
        "x" : 2266,
        "y" : 356
      },
      "to" : {
        "x" : 2319,
        "y" : 356
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 2260,
        "y" : 350
      },
      "b" : {
        "x" : 2272,
        "y" : 362
      },
      "s" : "\\\\",
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 2266,
        "y" : 356
      }
    },
    "inputs" : [ {
      "id" : 112293
    } ],
    "outputs" : [ {
      "id" : 112298,
      "points" : [ {
        "x" : 2309,
        "y" : 476
      }, {
        "x" : 2318,
        "y" : 462
      } ]
    }, {
      "id" : 112296,
      "points" : [ {
        "x" : 2362,
        "y" : 372
      } ]
    } ],
    "catalysts" : [ {
      "id" : 112289,
      "points" : [ {
        "x" : 2265,
        "y" : 203
      } ]
    } ]
  }, {
    "id" : 112232,
    "reactomeId" : 10645873,
    "displayName" : "TF:FVII:FXa ->TF:FVIIa:FXa (FXa catalyst)",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 638,
      "y" : 564
    },
    "minX" : 611,
    "maxX" : 644,
    "minY" : 557,
    "maxY" : 595,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 620,
        "y" : 557
      },
      "to" : {
        "x" : 638,
        "y" : 564
      }
    }, {
      "from" : {
        "x" : 638,
        "y" : 564
      },
      "to" : {
        "x" : 611,
        "y" : 595
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 613,
        "y" : 587
      },
      "b" : {
        "x" : 611,
        "y" : 595
      },
      "c" : {
        "x" : 619,
        "y" : 592
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 619,
        "y" : 592
      }
    },
    "reactionShape" : {
      "a" : {
        "x" : 632,
        "y" : 558
      },
      "b" : {
        "x" : 644,
        "y" : 570
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 638,
        "y" : 564
      }
    },
    "inputs" : [ {
      "id" : 112229
    } ],
    "outputs" : [ {
      "id" : 112233
    } ],
    "catalysts" : [ {
      "id" : 112229,
      "points" : [ {
        "x" : 620,
        "y" : 539
      }, {
        "x" : 637,
        "y" : 536
      } ]
    } ]
  }, {
    "id" : 112299,
    "reactomeId" : 10646233,
    "displayName" : "factor Va intermediate + factor Xa -> factor Va intermediate:factor Xa",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 736,
      "y" : 646
    },
    "minX" : 639,
    "maxX" : 742,
    "minY" : 602,
    "maxY" : 734,
    "reactionType" : "binding",
    "segments" : [ {
      "from" : {
        "x" : 736,
        "y" : 602
      },
      "to" : {
        "x" : 736,
        "y" : 646
      }
    }, {
      "from" : {
        "x" : 736,
        "y" : 646
      },
      "to" : {
        "x" : 639,
        "y" : 734
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 641,
        "y" : 726
      },
      "b" : {
        "x" : 639,
        "y" : 734
      },
      "c" : {
        "x" : 647,
        "y" : 732
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 647,
        "y" : 732
      }
    },
    "reactionShape" : {
      "c" : {
        "x" : 736,
        "y" : 646
      },
      "r" : 5,
      "type" : "CIRCLE",
      "centre" : {
        "x" : 736,
        "y" : 646
      }
    },
    "inputs" : [ {
      "id" : 112252,
      "points" : [ {
        "x" : 802,
        "y" : 436
      } ]
    }, {
      "id" : 112235,
      "points" : [ {
        "x" : 709,
        "y" : 507
      } ]
    } ],
    "outputs" : [ {
      "id" : 112300
    } ]
  }, {
    "id" : 112234,
    "reactomeId" : 10642871,
    "displayName" : "TF:FVIIa:FXa ->TF:FVIIa + FXa",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 629,
      "y" : 638
    },
    "minX" : 613,
    "maxX" : 635,
    "minY" : 624,
    "maxY" : 660,
    "reactionType" : "dissociation",
    "segments" : [ {
      "from" : {
        "x" : 613,
        "y" : 624
      },
      "to" : {
        "x" : 629,
        "y" : 638
      }
    }, {
      "from" : {
        "x" : 629,
        "y" : 638
      },
      "to" : {
        "x" : 629,
        "y" : 660
      }
    } ],
    "reactionShape" : {
      "c" : {
        "x" : 629,
        "y" : 638
      },
      "r" : 5,
      "r1" : 3,
      "type" : "DOUBLE_CIRCLE",
      "empty" : true,
      "centre" : {
        "x" : 629,
        "y" : 638
      }
    },
    "inputs" : [ {
      "id" : 112233
    } ],
    "outputs" : [ {
      "id" : 112235,
      "points" : [ {
        "x" : 702,
        "y" : 507
      }, {
        "x" : 653,
        "y" : 676
      } ]
    }, {
      "id" : 112236,
      "points" : [ {
        "x" : 613,
        "y" : 676
      } ]
    } ]
  }, {
    "id" : 112237,
    "reactomeId" : 10642879,
    "displayName" : "TF:FVIIa+FX -> TF:FVIIa:FXa + FX activation peptide (TF:F7a catalyst)",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 502,
      "y" : 466
    },
    "minX" : 429,
    "maxX" : 545,
    "minY" : 460,
    "maxY" : 472,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 429,
        "y" : 466
      },
      "to" : {
        "x" : 502,
        "y" : 466
      }
    }, {
      "from" : {
        "x" : 502,
        "y" : 466
      },
      "to" : {
        "x" : 545,
        "y" : 466
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 496,
        "y" : 460
      },
      "b" : {
        "x" : 508,
        "y" : 472
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 502,
        "y" : 466
      }
    },
    "inputs" : [ {
      "id" : 112238,
      "points" : [ {
        "x" : 386,
        "y" : 540
      } ]
    }, {
      "id" : 112226,
      "points" : [ {
        "x" : 375,
        "y" : 447
      } ]
    }, {
      "id" : 112228,
      "points" : [ {
        "x" : 358,
        "y" : 372
      } ]
    } ],
    "outputs" : [ {
      "id" : 112230,
      "points" : [ {
        "x" : 591,
        "y" : 431
      } ]
    }, {
      "id" : 112233,
      "points" : [ {
        "x" : 618,
        "y" : 595
      }, {
        "x" : 676,
        "y" : 554
      } ]
    } ],
    "catalysts" : [ {
      "id" : 112238,
      "points" : [ {
        "x" : 400,
        "y" : 540
      }, {
        "x" : 496,
        "y" : 488
      } ]
    } ],
    "activators" : [ {
      "id" : 112231,
      "points" : [ {
        "x" : 502,
        "y" : 554
      } ]
    } ]
  }, {
    "id" : 112301,
    "reactomeId" : 10567999,
    "displayName" : "factor V -> factor Va + factor V activation peptide (thrombin catalyst)",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 851,
      "y" : 216
    },
    "minX" : 830,
    "maxX" : 892,
    "minY" : 210,
    "maxY" : 222,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 830,
        "y" : 216
      },
      "to" : {
        "x" : 851,
        "y" : 216
      }
    }, {
      "from" : {
        "x" : 851,
        "y" : 216
      },
      "to" : {
        "x" : 892,
        "y" : 216
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 845,
        "y" : 210
      },
      "b" : {
        "x" : 857,
        "y" : 222
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 851,
        "y" : 216
      }
    },
    "inputs" : [ {
      "id" : 112250
    } ],
    "outputs" : [ {
      "id" : 112258,
      "points" : [ {
        "x" : 847,
        "y" : 538
      }, {
        "x" : 991,
        "y" : 589
      }, {
        "x" : 991,
        "y" : 252
      } ]
    }, {
      "id" : 112302,
      "points" : [ {
        "x" : 921,
        "y" : 205
      } ]
    } ],
    "catalysts" : [ {
      "id" : 112255,
      "points" : [ {
        "x" : 1061,
        "y" : 212
      }, {
        "x" : 1021,
        "y" : 140
      }, {
        "x" : 901,
        "y" : 141
      } ]
    } ],
    "inhibitors" : [ {
      "id" : 112303,
      "points" : [ {
        "x" : 1118,
        "y" : 973
      }, {
        "x" : 1075,
        "y" : 944
      }, {
        "x" : 1077,
        "y" : 319
      }, {
        "x" : 860,
        "y" : 230
      } ]
    }, {
      "id" : 112286,
      "points" : [ {
        "x" : 2322,
        "y" : 682
      }, {
        "x" : 2481,
        "y" : 682
      }, {
        "x" : 2474,
        "y" : 1
      }, {
        "x" : 852,
        "y" : 0
      } ]
    } ]
  }, {
    "id" : 112239,
    "reactomeId" : 10568049,
    "displayName" : "factor VII -> factor VIIa",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 223,
      "y" : 356
    },
    "minX" : 217,
    "maxX" : 229,
    "minY" : 323,
    "maxY" : 425,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 223,
        "y" : 323
      },
      "to" : {
        "x" : 223,
        "y" : 356
      }
    }, {
      "from" : {
        "x" : 223,
        "y" : 356
      },
      "to" : {
        "x" : 223,
        "y" : 425
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 219,
        "y" : 418
      },
      "b" : {
        "x" : 223,
        "y" : 425
      },
      "c" : {
        "x" : 227,
        "y" : 418
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 227,
        "y" : 418
      }
    },
    "reactionShape" : {
      "a" : {
        "x" : 217,
        "y" : 350
      },
      "b" : {
        "x" : 229,
        "y" : 362
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 223,
        "y" : 356
      }
    },
    "inputs" : [ {
      "id" : 112224
    } ],
    "outputs" : [ {
      "id" : 112240
    } ],
    "catalysts" : [ {
      "id" : 112235,
      "points" : [ {
        "x" : 706,
        "y" : 478
      }, {
        "x" : 713,
        "y" : 284
      }, {
        "x" : 155,
        "y" : 284
      }, {
        "x" : 156,
        "y" : 354
      } ]
    } ]
  }, {
    "id" : 112241,
    "reactomeId" : 10568039,
    "displayName" : "tissue factor (TF) + activated factor VII (F7a) -> TF:F7a complex",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 362,
      "y" : 519
    },
    "minX" : 333,
    "maxX" : 374,
    "minY" : 513,
    "maxY" : 540,
    "reactionType" : "binding",
    "segments" : [ {
      "from" : {
        "x" : 333,
        "y" : 517
      },
      "to" : {
        "x" : 362,
        "y" : 519
      }
    }, {
      "from" : {
        "x" : 362,
        "y" : 519
      },
      "to" : {
        "x" : 374,
        "y" : 540
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 367,
        "y" : 536
      },
      "b" : {
        "x" : 374,
        "y" : 540
      },
      "c" : {
        "x" : 374,
        "y" : 532
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 374,
        "y" : 532
      }
    },
    "reactionShape" : {
      "c" : {
        "x" : 362,
        "y" : 519
      },
      "r" : 5,
      "type" : "CIRCLE",
      "centre" : {
        "x" : 362,
        "y" : 519
      }
    },
    "inputs" : [ {
      "id" : 112222,
      "points" : [ {
        "x" : 293,
        "y" : 525
      } ]
    }, {
      "id" : 112240,
      "points" : [ {
        "x" : 240,
        "y" : 454
      } ]
    } ],
    "outputs" : [ {
      "id" : 112238
    } ],
    "activators" : [ {
      "id" : 112226,
      "points" : [ {
        "x" : 349,
        "y" : 458
      } ]
    } ]
  }, {
    "id" : 112304,
    "reactomeId" : 10568004,
    "displayName" : "prothrombin -> activated thrombin (factor IIa) + thrombin activation peptide (Xa catalyst)",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 1138,
      "y" : 423
    },
    "minX" : 1132,
    "maxX" : 1148,
    "minY" : 369,
    "maxY" : 493,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 1148,
        "y" : 493
      },
      "to" : {
        "x" : 1138,
        "y" : 423
      }
    }, {
      "from" : {
        "x" : 1138,
        "y" : 423
      },
      "to" : {
        "x" : 1139,
        "y" : 369
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 1132,
        "y" : 417
      },
      "b" : {
        "x" : 1144,
        "y" : 429
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 1138,
        "y" : 423
      }
    },
    "inputs" : [ {
      "id" : 112262
    } ],
    "outputs" : [ {
      "id" : 112255,
      "points" : [ {
        "x" : 1080,
        "y" : 255
      } ]
    }, {
      "id" : 112263,
      "points" : [ {
        "x" : 1182,
        "y" : 312
      } ]
    } ],
    "catalysts" : [ {
      "id" : 112235,
      "points" : [ {
        "x" : 715,
        "y" : 507
      }, {
        "x" : 804,
        "y" : 607
      }, {
        "x" : 1086,
        "y" : 607
      }, {
        "x" : 1086,
        "y" : 423
      } ]
    } ],
    "inhibitors" : [ {
      "id" : 112305,
      "points" : [ {
        "x" : 1283,
        "y" : 296
      }, {
        "x" : 1292,
        "y" : 296
      } ]
    } ]
  }, {
    "id" : 112242,
    "reactomeId" : 10645868,
    "displayName" : "TF:FVIIa+FIX -> TF:FVIIa:FIXa + FIX activation peptide (TF:F7a catalyst)",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 213,
      "y" : 897
    },
    "minX" : 187,
    "maxX" : 236,
    "minY" : 891,
    "maxY" : 903,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 187,
        "y" : 897
      },
      "to" : {
        "x" : 213,
        "y" : 897
      }
    }, {
      "from" : {
        "x" : 213,
        "y" : 897
      },
      "to" : {
        "x" : 236,
        "y" : 897
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 207,
        "y" : 891
      },
      "b" : {
        "x" : 219,
        "y" : 903
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 213,
        "y" : 897
      }
    },
    "inputs" : [ {
      "id" : 112243,
      "points" : [ {
        "x" : 136,
        "y" : 923
      } ]
    }, {
      "id" : 112238,
      "points" : [ {
        "x" : 373,
        "y" : 569
      }, {
        "x" : 181,
        "y" : 884
      } ]
    } ],
    "outputs" : [ {
      "id" : 112244,
      "points" : [ {
        "x" : 306,
        "y" : 933
      } ]
    }, {
      "id" : 112245,
      "points" : [ {
        "x" : 274,
        "y" : 883
      } ]
    } ],
    "catalysts" : [ {
      "id" : 112238,
      "points" : [ {
        "x" : 374,
        "y" : 569
      }, {
        "x" : 213,
        "y" : 875
      } ]
    } ],
    "activators" : [ {
      "id" : 112246,
      "points" : [ {
        "x" : 213,
        "y" : 928
      } ]
    } ]
  }, {
    "id" : 112247,
    "reactomeId" : 10645870,
    "displayName" : "TF:FVIIa:FIXa ->TF:FVIIa + FIXa",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 341,
      "y" : 896
    },
    "minX" : 316,
    "maxX" : 370,
    "minY" : 883,
    "maxY" : 902,
    "reactionType" : "dissociation",
    "segments" : [ {
      "from" : {
        "x" : 316,
        "y" : 883
      },
      "to" : {
        "x" : 341,
        "y" : 896
      }
    }, {
      "from" : {
        "x" : 341,
        "y" : 896
      },
      "to" : {
        "x" : 370,
        "y" : 896
      }
    } ],
    "reactionShape" : {
      "c" : {
        "x" : 341,
        "y" : 896
      },
      "r" : 5,
      "r1" : 3,
      "type" : "DOUBLE_CIRCLE",
      "empty" : true,
      "centre" : {
        "x" : 341,
        "y" : 896
      }
    },
    "inputs" : [ {
      "id" : 112245
    } ],
    "outputs" : [ {
      "id" : 112248,
      "points" : [ {
        "x" : 657,
        "y" : 1146
      } ]
    }, {
      "id" : 112238,
      "points" : [ {
        "x" : 380,
        "y" : 569
      }, {
        "x" : 404,
        "y" : 871
      } ]
    } ]
  }, {
    "id" : 112249,
    "reactomeId" : 10642100,
    "displayName" : "factor V -> factor Va intermediate + factor V activation peptide (FXa catalyst)",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 789,
      "y" : 284
    },
    "minX" : 783,
    "maxX" : 798,
    "minY" : 232,
    "maxY" : 319,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 798,
        "y" : 232
      },
      "to" : {
        "x" : 789,
        "y" : 284
      }
    }, {
      "from" : {
        "x" : 789,
        "y" : 284
      },
      "to" : {
        "x" : 789,
        "y" : 319
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 783,
        "y" : 278
      },
      "b" : {
        "x" : 795,
        "y" : 290
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 789,
        "y" : 284
      }
    },
    "inputs" : [ {
      "id" : 112250
    } ],
    "outputs" : [ {
      "id" : 112251,
      "points" : [ {
        "x" : 881,
        "y" : 360
      } ]
    }, {
      "id" : 112252,
      "points" : [ {
        "x" : 805,
        "y" : 393
      } ]
    } ],
    "catalysts" : [ {
      "id" : 112235,
      "points" : [ {
        "x" : 710,
        "y" : 478
      } ]
    } ],
    "inhibitors" : [ {
      "id" : 112253,
      "points" : [ {
        "x" : 676,
        "y" : 210
      } ]
    } ]
  }, {
    "id" : 112254,
    "reactomeId" : 10646004,
    "displayName" : "factor V -> factor Va intermediate + factor V activation peptide (thrombin catalyst)",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 815,
      "y" : 284
    },
    "minX" : 802,
    "maxX" : 821,
    "minY" : 232,
    "maxY" : 317,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 802,
        "y" : 232
      },
      "to" : {
        "x" : 815,
        "y" : 284
      }
    }, {
      "from" : {
        "x" : 815,
        "y" : 284
      },
      "to" : {
        "x" : 815,
        "y" : 317
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 809,
        "y" : 278
      },
      "b" : {
        "x" : 821,
        "y" : 290
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 815,
        "y" : 284
      }
    },
    "inputs" : [ {
      "id" : 112250
    } ],
    "outputs" : [ {
      "id" : 112251,
      "points" : [ {
        "x" : 887,
        "y" : 360
      } ]
    }, {
      "id" : 112252,
      "points" : [ {
        "x" : 810,
        "y" : 393
      } ]
    } ],
    "catalysts" : [ {
      "id" : 112255,
      "points" : [ {
        "x" : 1008,
        "y" : 231
      }, {
        "x" : 983,
        "y" : 231
      } ]
    } ]
  } ],
  "compartments" : [ {
    "id" : 112307,
    "reactomeId" : 70101,
    "displayName" : "cytosol",
    "schemaClass" : "Compartment",
    "renderableClass" : "Compartment",
    "position" : {
      "x" : 1776,
      "y" : 713
    },
    "minX" : 1256,
    "maxX" : 2296,
    "minY" : 383,
    "maxY" : 1044,
    "prop" : {
      "x" : 1256,
      "y" : 383,
      "width" : 1040,
      "height" : 661
    },
    "textPosition" : {
      "x" : 1893,
      "y" : 426
    },
    "insets" : {
      "x" : 1266,
      "y" : 393,
      "width" : 1020,
      "height" : 641
    },
    "bgColor" : {
      "r" : 250,
      "g" : 240,
      "b" : 240
    },
    "componentIds" : [ 112260, 112266, 112268, 112267, 112286, 112272, 112293, 112292, 112298 ]
  }, {
    "id" : 112306,
    "reactomeId" : 70101,
    "displayName" : "cytosol",
    "schemaClass" : "Compartment",
    "renderableClass" : "Compartment",
    "position" : {
      "x" : 324,
      "y" : 714
    },
    "minX" : 35,
    "maxX" : 614,
    "minY" : 545,
    "maxY" : 884,
    "prop" : {
      "x" : 35,
      "y" : 545,
      "width" : 579,
      "height" : 339
    },
    "textPosition" : {
      "x" : 297,
      "y" : 571
    },
    "insets" : {
      "x" : 45,
      "y" : 555,
      "width" : 559,
      "height" : 319
    },
    "bgColor" : {
      "r" : 250,
      "g" : 240,
      "b" : 240
    },
    "componentIds" : [ 112221, 112222, 112229, 112238, 112233, 112225, 112300, 112236, 112245, 112231 ]
  }, {
    "id" : 112310,
    "reactomeId" : 70101,
    "displayName" : "cytosol",
    "schemaClass" : "Compartment",
    "renderableClass" : "Compartment",
    "position" : {
      "x" : 264,
      "y" : 1139
    },
    "minX" : 60,
    "maxX" : 468,
    "minY" : 1022,
    "maxY" : 1256,
    "prop" : {
      "x" : 60,
      "y" : 1022,
      "width" : 408,
      "height" : 234
    },
    "textPosition" : {
      "x" : 82,
      "y" : 1035
    },
    "insets" : {
      "x" : 70,
      "y" : 1032,
      "width" : 388,
      "height" : 214
    },
    "bgColor" : {
      "r" : 250,
      "g" : 240,
      "b" : 240
    },
    "componentIds" : [ 112269, 112313 ]
  }, {
    "id" : 112313,
    "reactomeId" : 17957,
    "displayName" : "endoplasmic reticulum lumen",
    "schemaClass" : "Compartment",
    "renderableClass" : "Compartment",
    "position" : {
      "x" : 265,
      "y" : 1138
    },
    "minX" : 103,
    "maxX" : 428,
    "minY" : 1074,
    "maxY" : 1203,
    "prop" : {
      "x" : 103,
      "y" : 1074,
      "width" : 325,
      "height" : 129
    },
    "textPosition" : {
      "x" : 201,
      "y" : 1137
    },
    "insets" : {
      "x" : 113,
      "y" : 1084,
      "width" : 305,
      "height" : 109
    },
    "bgColor" : {
      "r" : 250,
      "g" : 240,
      "b" : 240
    },
    "componentIds" : [ 112270 ]
  } ],
  "notes" : [ ],
  "links" : [ {
    "id" : 112321,
    "renderableClass" : "Interaction",
    "position" : {
      "x" : 6,
      "y" : 626
    },
    "minX" : 0,
    "maxX" : 501,
    "minY" : 119,
    "maxY" : 632,
    "interactionType" : "Activate",
    "segments" : [ {
      "from" : {
        "x" : 392,
        "y" : 120
      },
      "to" : {
        "x" : 6,
        "y" : 119
      }
    }, {
      "from" : {
        "x" : 6,
        "y" : 119
      },
      "to" : {
        "x" : 6,
        "y" : 626
      }
    }, {
      "from" : {
        "x" : 6,
        "y" : 626
      },
      "to" : {
        "x" : 501,
        "y" : 626
      }
    }, {
      "from" : {
        "x" : 501,
        "y" : 626
      },
      "to" : {
        "x" : 501,
        "y" : 589
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 505,
        "y" : 596
      },
      "b" : {
        "x" : 501,
        "y" : 589
      },
      "c" : {
        "x" : 497,
        "y" : 596
      },
      "type" : "ARROW",
      "empty" : true,
      "centre" : {
        "x" : 497,
        "y" : 596
      }
    },
    "reactionShape" : {
      "a" : {
        "x" : 0,
        "y" : 620
      },
      "b" : {
        "x" : 12,
        "y" : 632
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 6,
        "y" : 626
      }
    },
    "inputs" : [ {
      "id" : 112319
    } ],
    "outputs" : [ {
      "id" : 112231
    } ]
  }, {
    "id" : 112320,
    "renderableClass" : "Interaction",
    "position" : {
      "x" : 603,
      "y" : 168
    },
    "minX" : 572,
    "maxX" : 634,
    "minY" : 155,
    "maxY" : 181,
    "interactionType" : "Activate",
    "segments" : [ {
      "from" : {
        "x" : 572,
        "y" : 155
      },
      "to" : {
        "x" : 634,
        "y" : 181
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 626,
        "y" : 182
      },
      "b" : {
        "x" : 634,
        "y" : 181
      },
      "c" : {
        "x" : 629,
        "y" : 175
      },
      "type" : "ARROW",
      "empty" : true,
      "centre" : {
        "x" : 629,
        "y" : 175
      }
    },
    "reactionShape" : {
      "a" : {
        "x" : 597,
        "y" : 162
      },
      "b" : {
        "x" : 609,
        "y" : 174
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 603,
        "y" : 168
      }
    },
    "inputs" : [ {
      "id" : 112319
    } ],
    "outputs" : [ {
      "id" : 112253
    } ]
  } ],
  "shadows" : [ {
    "id" : 112323,
    "reactomeId" : 10648068,
    "displayName" : "Initiation of coagulation cascade",
    "schemaClass" : "Pathway",
    "renderableClass" : "Shadow",
    "position" : {
      "x" : 717,
      "y" : 678
    },
    "minX" : 18,
    "maxX" : 1416,
    "minY" : 174,
    "maxY" : 1182,
    "prop" : {
      "x" : 18,
      "y" : 174,
      "width" : 1398,
      "height" : 1008
    },
    "points" : [ {
      "x" : 18,
      "y" : 174
    }, {
      "x" : 1416,
      "y" : 174
    }, {
      "x" : 1416,
      "y" : 1182
    }, {
      "x" : 18,
      "y" : 1182
    } ],
    "colour" : "#dc3912"
  }, {
    "id" : 112322,
    "reactomeId" : 10648038,
    "displayName" : "Fibrin formation",
    "schemaClass" : "Pathway",
    "renderableClass" : "Shadow",
    "position" : {
      "x" : 1726,
      "y" : 383
    },
    "minX" : 1001,
    "maxX" : 2452,
    "minY" : 48,
    "maxY" : 718,
    "prop" : {
      "x" : 1001,
      "y" : 48,
      "width" : 1451,
      "height" : 107
    },
    "points" : [ {
      "x" : 1001,
      "y" : 48
    }, {
      "x" : 2452,
      "y" : 48
    }, {
      "x" : 2452,
      "y" : 718
    }, {
      "x" : 1001,
      "y" : 718
    } ],
    "colour" : "#4684ee"
  }, {
    "id" : 112324,
    "reactomeId" : 10648070,
    "displayName" : "Amplification and propagation of coagulation cascade",
    "schemaClass" : "Pathway",
    "renderableClass" : "Shadow",
    "position" : {
      "x" : 1184,
      "y" : 668
    },
    "minX" : 40,
    "maxX" : 2329,
    "minY" : 155,
    "maxY" : 1182,
    "prop" : {
      "x" : 1416,
      "y" : 718,
      "width" : 913,
      "height" : 464
    },
    "points" : [ {
      "x" : 40,
      "y" : 155
    }, {
      "x" : 2329,
      "y" : 155
    }, {
      "x" : 2329,
      "y" : 1182
    }, {
      "x" : 40,
      "y" : 1182
    } ],
    "colour" : "#008000"
  } ],
  "minX" : 0,
  "maxX" : 2481,
  "minY" : 0,
  "maxY" : 1256,
  "disease" : false
}