{
  "dbId" : 10557555,
  "stId" : "R-SSC-909733",
  "speciesName" : "Sus scrofa",
  "nodes" : [ {
    "dbId" : 10483358,
    "stId" : "R-SSC-918193",
    "displayName" : "IFNAR2:JAK1:STAT2 [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 49633,
    "diagramIds" : [ 103854 ],
    "parents" : [ 10483364, 10483362, 10483360 ],
    "children" : [ 10483332, 10483334, 10479912 ]
  }, {
    "dbId" : 10483353,
    "stId" : "R-SSC-9833154",
    "displayName" : "multiubiquitinated STAT2 [cytosol]",
    "schemaClass" : "Complex",
    "speciesId" : 49633,
    "diagramIds" : [ 103874 ],
    "parents" : [ ],
    "children" : [ 10483334, 10447615 ]
  }, {
    "dbId" : 9696149,
    "stId" : "R-ALL-9696149",
    "displayName" : "recombinant IFNB1a [extracellular region]",
    "schemaClass" : "ProteinDrug",
    "speciesId" : 0,
    "identifier" : "8339",
    "standardIdentifier" : "iuphar.ligand:8339",
    "parents" : [ 9696187 ],
    "children" : [ ]
  }, {
    "dbId" : 10483351,
    "stId" : "R-SSC-909696",
    "displayName" : "IFNA/B:IFNAR2:p-JAK1:STAT2:p-IFNAR1:p-TYK2:STAT2 [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 49633,
    "diagramIds" : [ 103873 ],
    "parents" : [ ],
    "children" : [ 10483312, 10483349, 10483336 ]
  }, {
    "dbId" : 10483349,
    "stId" : "R-SSC-909701",
    "displayName" : "STAT2:p-IFNAR1:p-TYK2 [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 49633,
    "parents" : [ 10483351 ],
    "children" : [ 10483315, 10483334, 10483321 ]
  }, {
    "dbId" : 10483347,
    "stId" : "R-SSC-909704",
    "displayName" : "IFNA/B:IFNAR2:p-JAK1:STAT2:p-IFNAR1:p-TYK2 [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 49633,
    "diagramIds" : [ 103869 ],
    "parents" : [ ],
    "children" : [ 10483345, 10483343 ]
  }, {
    "dbId" : 10483345,
    "stId" : "R-SSC-909692",
    "displayName" : "IFNA/B:IFNAR2:p-JAK1:STAT2 [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 49633,
    "parents" : [ 10488617, 10483424, 10483419, 10483347 ],
    "children" : [ 10483312, 10483336 ]
  }, {
    "dbId" : 10483343,
    "stId" : "R-SSC-909694",
    "displayName" : "p-IFNAR1:p-TYK2 [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 49633,
    "parents" : [ 10483347 ],
    "children" : [ 10483315, 10483321 ]
  }, {
    "dbId" : 10483338,
    "stId" : "R-SSC-909697",
    "displayName" : "IFNA/B:IFNAR2:p-JAK1:STAT2:p-IFNAR1:p-TYK2:p-STAT2 [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 49633,
    "diagramIds" : [ 103878 ],
    "parents" : [ ],
    "children" : [ 10483328, 10483312, 10483336 ]
  }, {
    "dbId" : 10483336,
    "stId" : "R-SSC-909715",
    "displayName" : "IFNAR2:p-JAK1:STAT2 [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 49633,
    "parents" : [ 10488612, 10483345, 10483351, 10483400, 10483338 ],
    "children" : [ 10481026, 10483332, 10483334 ]
  }, {
    "dbId" : 10483334,
    "stId" : "R-SSC-882029",
    "displayName" : "STAT2 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 49633,
    "diagramIds" : [ 103872 ],
    "identifier" : "O02799",
    "standardIdentifier" : "uniprot:O02799",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "STAT2" ],
    "parents" : [ 10483358, 10483353, 10483349, 10483336 ],
    "children" : [ ]
  }, {
    "dbId" : 10468485,
    "stId" : "R-SSC-197938",
    "displayName" : "PTPN6 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 49633,
    "diagramIds" : [ 103910 ],
    "identifier" : "A0A4X1UZH9",
    "standardIdentifier" : "uniprot:A0A4X1UZH9",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ ],
    "children" : [ ]
  }, {
    "dbId" : 10483332,
    "stId" : "R-SSC-877333",
    "displayName" : "IFNAR2 [plasma membrane]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 49633,
    "diagramIds" : [ 103900 ],
    "identifier" : "A0A286ZIT4",
    "standardIdentifier" : "uniprot:A0A286ZIT4",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "IFNAR2" ],
    "parents" : [ 10483521, 10483358, 10483336 ],
    "children" : [ ]
  }, {
    "dbId" : 9678984,
    "stId" : "R-ALL-9678984",
    "displayName" : "JAK1,2 inhibitors [cytosol]",
    "schemaClass" : "DefinedSet",
    "speciesId" : 0,
    "diagramIds" : [ 103921 ],
    "parents" : [ 10483362 ],
    "children" : [ 9678829, 9717004, 9678779, 9678786 ]
  }, {
    "dbId" : 10481026,
    "stId" : "R-SSC-451921",
    "displayName" : "phospho-p-Y-JAK1 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 49633,
    "identifier" : "A0A286ZLI2",
    "standardIdentifier" : "uniprot:A0A286ZLI2",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 10483336 ],
    "children" : [ ]
  }, {
    "dbId" : 10483328,
    "stId" : "R-SSC-909709",
    "displayName" : "p-STAT2:p-IFNAR1:p-TYK2 [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 49633,
    "parents" : [ 10483338 ],
    "children" : [ 10483315, 10483321, 10483326 ]
  }, {
    "dbId" : 10483390,
    "stId" : "R-SSC-909693",
    "displayName" : "p-STAT2:p-STAT1 [nucleoplasm]",
    "schemaClass" : "Complex",
    "speciesId" : 49633,
    "parents" : [ 10483394 ],
    "children" : [ 10483384, 10483388 ]
  }, {
    "dbId" : 10483388,
    "stId" : "R-SSC-909673",
    "displayName" : "phospho-STAT2 [nucleoplasm]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 49633,
    "identifier" : "O02799",
    "standardIdentifier" : "uniprot:O02799",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "STAT2" ],
    "parents" : [ 10483390 ],
    "children" : [ ]
  }, {
    "dbId" : 10483386,
    "stId" : "R-SSC-909684",
    "displayName" : "phospho-STAT1 [nucleoplasm]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 49633,
    "identifier" : "G9BFT9",
    "standardIdentifier" : "uniprot:G9BFT9",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "STAT1" ],
    "parents" : [ 10483582 ],
    "children" : [ ]
  }, {
    "dbId" : 10483384,
    "stId" : "R-SSC-909676",
    "displayName" : "phospho-STAT1 [nucleoplasm]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 49633,
    "identifier" : "G9BFT9",
    "standardIdentifier" : "uniprot:G9BFT9",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "STAT1" ],
    "parents" : [ 10483390 ],
    "children" : [ ]
  }, {
    "dbId" : 9678779,
    "stId" : "R-ALL-9678779",
    "displayName" : "tofacitinib [cytosol]",
    "schemaClass" : "ChemicalDrug",
    "speciesId" : 0,
    "identifier" : "5677",
    "standardIdentifier" : "iuphar.ligand:5677",
    "chebiIdentifier" : "chebi:71200",
    "parents" : [ 9678619, 9678984 ],
    "children" : [ ]
  }, {
    "dbId" : 9696187,
    "stId" : "R-HSA-9696187",
    "displayName" : "type 1 interferon analogs [extracellular region]",
    "schemaClass" : "DefinedSet",
    "speciesId" : 48887,
    "diagramIds" : [ 103925 ],
    "parents" : [ 10483364 ],
    "children" : [ 9734377, 9696186, 9734435, 9734403, 9696149, 9734422, 9734438 ]
  }, {
    "dbId" : 9696186,
    "stId" : "R-ALL-9696186",
    "displayName" : "recombinant IFNB1b [extracellular region]",
    "schemaClass" : "ProteinDrug",
    "speciesId" : 0,
    "identifier" : "8340",
    "standardIdentifier" : "iuphar.ligand:8340",
    "chebiIdentifier" : "chebi:5938",
    "parents" : [ 9696187 ],
    "children" : [ ]
  }, {
    "dbId" : 10483382,
    "stId" : "R-SSC-9710965",
    "displayName" : "ISGF3:KPNA1:KPNB1 [cytosol]",
    "schemaClass" : "Complex",
    "speciesId" : 49633,
    "diagramIds" : [ 103886 ],
    "parents" : [ 10548059 ],
    "children" : [ 10483380, 10469094 ]
  }, {
    "dbId" : 10483380,
    "stId" : "R-SSC-9710958",
    "displayName" : "ISGF3:KPNA1 [cytosol]",
    "schemaClass" : "Complex",
    "speciesId" : 49633,
    "parents" : [ 10548055, 10483382 ],
    "children" : [ 10483378, 10469090 ]
  }, {
    "dbId" : 10483378,
    "stId" : "R-SSC-909698",
    "displayName" : "ISGF3 [cytosol]",
    "schemaClass" : "Complex",
    "speciesId" : 49633,
    "diagramIds" : [ 103884 ],
    "parents" : [ 10548051, 10483380 ],
    "children" : [ 10483376, 10483372 ]
  }, {
    "dbId" : 10483376,
    "stId" : "R-SSC-909702",
    "displayName" : "p-STAT2:p-STAT1 [cytosol]",
    "schemaClass" : "Complex",
    "speciesId" : 49633,
    "diagramIds" : [ 103881 ],
    "parents" : [ 10483378, 10483398 ],
    "children" : [ 10482792, 10483326 ]
  }, {
    "dbId" : 10483372,
    "stId" : "R-SSC-879183",
    "displayName" : "IRF9 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 49633,
    "diagramIds" : [ 103883 ],
    "identifier" : "A0A8D1G4V5",
    "standardIdentifier" : "uniprot:A0A8D1G4V5",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "IRF9" ],
    "parents" : [ 10483378 ],
    "children" : [ ]
  }, {
    "dbId" : 10483364,
    "stId" : "R-SSC-9696161",
    "displayName" : "IFNAR2:JAK1:STAT2:type 1 interferon analogs [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 49633,
    "diagramIds" : [ 103856 ],
    "parents" : [ ],
    "children" : [ 9696187, 10483358 ]
  }, {
    "dbId" : 10483362,
    "stId" : "R-SSC-9678951",
    "displayName" : "IFNAR2:JAK1:STAT2:JAK1,2 inhibitors [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 49633,
    "diagramIds" : [ 103857 ],
    "parents" : [ ],
    "children" : [ 9678984, 10483358 ]
  }, {
    "dbId" : 10483360,
    "stId" : "R-SSC-918195",
    "displayName" : "IFNA/B:IFNAR2:JAK1:STAT2 [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 49633,
    "diagramIds" : [ 103855 ],
    "parents" : [ 10483408 ],
    "children" : [ 10483312, 10483358 ]
  }, {
    "dbId" : 10483422,
    "stId" : "R-SSC-912684",
    "displayName" : "p-IFNAR1:p-TYK2:SOCS-1/SOCS-3 [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 49633,
    "parents" : [ 10483424 ],
    "children" : [ 10483315, 10482760, 10483321 ]
  }, {
    "dbId" : 10459101,
    "stId" : "R-SSC-162563",
    "displayName" : "PTPN11 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 49633,
    "diagramIds" : [ 103915 ],
    "identifier" : "A0A480LMF4",
    "standardIdentifier" : "uniprot:A0A480LMF4",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ ],
    "children" : [ ]
  }, {
    "dbId" : 10483419,
    "stId" : "R-SSC-909705",
    "displayName" : "IFNA/B:IFNAR2:p-JAK1:STAT2:IFNAR1:p-TYK2 [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 49633,
    "diagramIds" : [ 103864 ],
    "parents" : [ ],
    "children" : [ 10483345, 10483417 ]
  }, {
    "dbId" : 10483417,
    "stId" : "R-SSC-909707",
    "displayName" : "IFNAR1:p-TYK2 [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 49633,
    "parents" : [ 10483419 ],
    "children" : [ 10483315, 10483404 ]
  }, {
    "dbId" : 10483410,
    "stId" : "R-SSC-9678695",
    "displayName" : "IFNAR1:TYK2:TYK2 inhibitors [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 49633,
    "diagramIds" : [ 103861 ],
    "parents" : [ ],
    "children" : [ 9678619, 10483406 ]
  }, {
    "dbId" : 10483408,
    "stId" : "R-SSC-909703",
    "displayName" : "IFNA/B:IFNAR2:JAK1:STAT2:IFNAR1:TYK2 [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 49633,
    "diagramIds" : [ 103860 ],
    "parents" : [ ],
    "children" : [ 10483360, 10483406 ]
  }, {
    "dbId" : 9678786,
    "stId" : "R-ALL-9678786",
    "displayName" : "ruxolitinib [cytosol]",
    "schemaClass" : "ChemicalDrug",
    "speciesId" : 0,
    "identifier" : "5688",
    "standardIdentifier" : "iuphar.ligand:5688",
    "chebiIdentifier" : "chebi:66919",
    "parents" : [ 9678619, 9678984 ],
    "children" : [ ]
  }, {
    "dbId" : 10483406,
    "stId" : "R-SSC-909708",
    "displayName" : "IFNAR1:TYK2 [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 49633,
    "diagramIds" : [ 103859 ],
    "parents" : [ 10488617, 10483410, 10483408 ],
    "children" : [ 10479850, 10483404 ]
  }, {
    "dbId" : 10483404,
    "stId" : "R-SSC-877334",
    "displayName" : "IFNAR1 [plasma membrane]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 49633,
    "identifier" : "A0A480S426",
    "standardIdentifier" : "uniprot:A0A480S426",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "IFNAR1" ],
    "parents" : [ 10483406, 10483417 ],
    "children" : [ ]
  }, {
    "dbId" : 10483400,
    "stId" : "R-SSC-909711",
    "displayName" : "IFNA/B:IFNAR2:p-JAK1:STAT2:p-IFNAR1:p-TYK2:p-STAT2:p-STAT1 [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 49633,
    "diagramIds" : [ 103880 ],
    "parents" : [ ],
    "children" : [ 10483312, 10483398, 10483336 ]
  }, {
    "dbId" : 10483398,
    "stId" : "R-SSC-909712",
    "displayName" : "p-STAT2:p-STAT1:p-IFNAR1:p-TYK2 [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 49633,
    "parents" : [ 10483400 ],
    "children" : [ 10483376, 10483315, 10483321 ]
  }, {
    "dbId" : 10483394,
    "stId" : "R-SSC-913527",
    "displayName" : "ISGF3 [nucleoplasm]",
    "schemaClass" : "Complex",
    "speciesId" : 49633,
    "diagramIds" : [ 103887 ],
    "parents" : [ ],
    "children" : [ 10483392, 10483390 ]
  }, {
    "dbId" : 10483392,
    "stId" : "R-SSC-913522",
    "displayName" : "IRF9 [nucleoplasm]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 49633,
    "identifier" : "A0A8D1G4V5",
    "standardIdentifier" : "uniprot:A0A8D1G4V5",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "IRF9" ],
    "parents" : [ 10483394 ],
    "children" : [ ]
  }, {
    "dbId" : 10447615,
    "stId" : "R-SSC-113595",
    "displayName" : "Ub [cytosol]",
    "schemaClass" : "DefinedSet",
    "speciesId" : 49633,
    "parents" : [ 10483353 ],
    "children" : [ 10447591, 10447589, 10447587 ]
  }, {
    "dbId" : 10469114,
    "stId" : "R-SSC-180714",
    "displayName" : "KPNB1 [nucleoplasm]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 49633,
    "diagramIds" : [ 103889 ],
    "identifier" : "F1RWJ5",
    "standardIdentifier" : "uniprot:F1RWJ5",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "KPNB1" ],
    "parents" : [ ],
    "children" : [ ]
  }, {
    "dbId" : 10469112,
    "stId" : "R-SSC-188865",
    "displayName" : "KPNA1 [nucleoplasm]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 49633,
    "diagramIds" : [ 103888 ],
    "identifier" : "I3L9F7",
    "standardIdentifier" : "uniprot:I3L9F7",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ ],
    "children" : [ ]
  }, {
    "dbId" : 10479850,
    "stId" : "R-SSC-877348",
    "displayName" : "TYK2 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 49633,
    "identifier" : "F1S3L9",
    "standardIdentifier" : "uniprot:F1S3L9",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 10483406 ],
    "children" : [ ]
  }, {
    "dbId" : 10447591,
    "stId" : "R-SSC-939214",
    "displayName" : "UBC [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 49633,
    "identifier" : "P0CG68",
    "standardIdentifier" : "uniprot:P0CG68",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "UBC" ],
    "parents" : [ 10447615 ],
    "children" : [ ]
  }, {
    "dbId" : 10469094,
    "stId" : "R-SSC-180733",
    "displayName" : "KPNB1 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 49633,
    "diagramIds" : [ 103931 ],
    "identifier" : "F1RWJ5",
    "standardIdentifier" : "uniprot:F1RWJ5",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "KPNB1" ],
    "parents" : [ 10483580, 10483382 ],
    "children" : [ ]
  }, {
    "dbId" : 10447589,
    "stId" : "R-SSC-939203",
    "displayName" : "UBA52 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 49633,
    "identifier" : "P63053",
    "standardIdentifier" : "uniprot:P63053",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "UBA52" ],
    "parents" : [ 10447615 ],
    "children" : [ ]
  }, {
    "dbId" : 10447587,
    "stId" : "R-SSC-939205",
    "displayName" : "RPS27A [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 49633,
    "identifier" : "A0A287AZA7",
    "standardIdentifier" : "uniprot:A0A287AZA7",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "RPS27A" ],
    "parents" : [ 10447615 ],
    "children" : [ ]
  }, {
    "dbId" : 9734377,
    "stId" : "R-ALL-9734377",
    "displayName" : "recombinant IFNA2b [extracellular region]",
    "schemaClass" : "ProteinDrug",
    "speciesId" : 0,
    "identifier" : "8338",
    "standardIdentifier" : "iuphar.ligand:8338",
    "parents" : [ 9696187 ],
    "children" : [ ]
  }, {
    "dbId" : 10469090,
    "stId" : "R-SSC-180612",
    "displayName" : "KPNA1 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 49633,
    "diagramIds" : [ 103927 ],
    "identifier" : "I3L9F7",
    "standardIdentifier" : "uniprot:I3L9F7",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 10483580, 10548053, 10483380 ],
    "children" : [ ]
  }, {
    "dbId" : 9678829,
    "stId" : "R-ALL-9678829",
    "displayName" : "baricitinib [cytosol]",
    "schemaClass" : "ChemicalDrug",
    "speciesId" : 0,
    "identifier" : "7792",
    "standardIdentifier" : "iuphar.ligand:7792",
    "chebiIdentifier" : "chebi:95341",
    "parents" : [ 9678619, 9678984 ],
    "children" : [ ]
  }, {
    "dbId" : 10483424,
    "stId" : "R-SSC-912681",
    "displayName" : "p-TYK2:p-IFNAR1:SOCS-1/SOCS-3:IFNA/B:IFNAR2:p-JAK1:STAT2 [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 49633,
    "diagramIds" : [ 103866 ],
    "parents" : [ ],
    "children" : [ 10483345, 10483422 ]
  }, {
    "dbId" : 10488608,
    "stId" : "R-SSC-997303",
    "displayName" : "p-STAT2:STAT1 [cytosol]",
    "schemaClass" : "Complex",
    "speciesId" : 49633,
    "parents" : [ 10488610 ],
    "children" : [ 10482786, 10483326 ]
  }, {
    "dbId" : 10483230,
    "stId" : "R-SSC-877339-3",
    "displayName" : "IFNA10 [extracellular region]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 49633,
    "identifier" : "A0A5G2QHB7",
    "standardIdentifier" : "uniprot:A0A5G2QHB7",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 10483272 ],
    "children" : [ ]
  }, {
    "dbId" : 9734422,
    "stId" : "R-ALL-9734422",
    "displayName" : "peginterferon alfa-2b [extracellular region]",
    "schemaClass" : "ProteinDrug",
    "speciesId" : 0,
    "identifier" : "7462",
    "standardIdentifier" : "iuphar.ligand:7462",
    "parents" : [ 9696187 ],
    "children" : [ ]
  }, {
    "dbId" : 10488610,
    "stId" : "R-SSC-997302",
    "displayName" : "p-STAT2:STAT1:p-IFNAR1:p-TYK2 [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 49633,
    "parents" : [ 10488612 ],
    "children" : [ 10483315, 10483321, 10488608 ]
  }, {
    "dbId" : 10488612,
    "stId" : "R-SSC-997304",
    "displayName" : "IFNA/B:IFNAR2:p-JAK1:STAT2:p-IFNAR1:p-TYK2:p-STAT2:STAT1 [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 49633,
    "diagramIds" : [ 103913 ],
    "parents" : [ ],
    "children" : [ 10483312, 10483336, 10488610 ]
  }, {
    "dbId" : 10483226,
    "stId" : "R-SSC-877339-2",
    "displayName" : "IFN-ALPHA-8 [extracellular region]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 49633,
    "identifier" : "A0A287BCH3",
    "standardIdentifier" : "uniprot:A0A287BCH3",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "IFN-ALPHA-8" ],
    "parents" : [ 10483272 ],
    "children" : [ ]
  }, {
    "dbId" : 10471962,
    "stId" : "R-SSC-210625",
    "displayName" : "PTPN1 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 49633,
    "diagramIds" : [ 103906 ],
    "identifier" : "A0A287BAQ6",
    "standardIdentifier" : "uniprot:A0A287BAQ6",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ ],
    "children" : [ ]
  }, {
    "dbId" : 9678619,
    "stId" : "R-ALL-9678619",
    "displayName" : "TYK2 inhibitors [cytosol]",
    "schemaClass" : "DefinedSet",
    "speciesId" : 0,
    "diagramIds" : [ 103923 ],
    "parents" : [ 10483410 ],
    "children" : [ 9678829, 9678779, 9678786 ]
  }, {
    "dbId" : 10483222,
    "stId" : "R-SSC-877339",
    "displayName" : "IFN-ALPHA-15 [extracellular region]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 49633,
    "identifier" : "A0A287AUX7",
    "standardIdentifier" : "uniprot:A0A287AUX7",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "IFN-ALPHA-15" ],
    "parents" : [ 10483272 ],
    "children" : [ ]
  }, {
    "dbId" : 10488617,
    "stId" : "R-SSC-997300",
    "displayName" : "IFNA/B:IFNAR2:p-JAK1:STAT2:IFNAR1:TYK2 [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 49633,
    "diagramIds" : [ 103905 ],
    "parents" : [ ],
    "children" : [ 10483345, 10483406 ]
  }, {
    "dbId" : 9734403,
    "stId" : "R-ALL-9734403",
    "displayName" : "recombinant IFNA2a [extracellular region]",
    "schemaClass" : "ProteinDrug",
    "speciesId" : 0,
    "identifier" : "4960",
    "standardIdentifier" : "iuphar.ligand:4960",
    "chebiIdentifier" : "chebi:5937",
    "parents" : [ 9696187 ],
    "children" : [ ]
  }, {
    "dbId" : 9717004,
    "stId" : "R-ALL-9717004",
    "displayName" : "delgocitinib [cytosol]",
    "schemaClass" : "ChemicalDrug",
    "speciesId" : 0,
    "identifier" : "9619",
    "standardIdentifier" : "iuphar.ligand:9619",
    "chebiIdentifier" : "chebi:167600",
    "parents" : [ 9678984 ],
    "children" : [ ]
  }, {
    "dbId" : 10483519,
    "stId" : "R-SSC-912325",
    "displayName" : "USP18 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 49633,
    "diagramIds" : [ 103899 ],
    "identifier" : "A0A287A210",
    "standardIdentifier" : "uniprot:A0A287A210",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "USP18" ],
    "parents" : [ 10483521 ],
    "children" : [ ]
  }, {
    "dbId" : 10483262,
    "stId" : "R-SSC-877339-11",
    "displayName" : "IFN-alpha-2 [extracellular region]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 49633,
    "identifier" : "Q304W0",
    "standardIdentifier" : "uniprot:Q304W0",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "IFN-alpha-2" ],
    "parents" : [ 10483272 ],
    "children" : [ ]
  }, {
    "dbId" : 10483258,
    "stId" : "R-SSC-877339-10",
    "displayName" : "LOC100156936 [extracellular region]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 49633,
    "identifier" : "Q1KNJ3",
    "standardIdentifier" : "uniprot:Q1KNJ3",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "LOC100156936" ],
    "parents" : [ 10483272 ],
    "children" : [ ]
  }, {
    "dbId" : 10483254,
    "stId" : "R-SSC-877339-9",
    "displayName" : "IFN-alpha-17 [extracellular region]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 49633,
    "identifier" : "C8CKA8",
    "standardIdentifier" : "uniprot:C8CKA8",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "IFN-alpha-17" ],
    "parents" : [ 10483272 ],
    "children" : [ ]
  }, {
    "dbId" : 29356,
    "stId" : "R-ALL-29356",
    "displayName" : "H2O [cytosol]",
    "schemaClass" : "SimpleEntity",
    "speciesId" : 0,
    "diagramIds" : [ 103908, 103912, 103903 ],
    "identifier" : "15377",
    "standardIdentifier" : "chebi:15377",
    "referenceType" : "ReferenceMolecule",
    "parents" : [ ],
    "children" : [ ]
  }, {
    "dbId" : 10483250,
    "stId" : "R-SSC-877339-8",
    "displayName" : "IFN-alpha-13 [extracellular region]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 49633,
    "identifier" : "C8CKA4",
    "standardIdentifier" : "uniprot:C8CKA4",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "IFN-alpha-13" ],
    "parents" : [ 10483272 ],
    "children" : [ ]
  }, {
    "dbId" : 10483246,
    "stId" : "R-SSC-877339-7",
    "displayName" : "IFN-alpha-9 [extracellular region]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 49633,
    "identifier" : "C8CKA0",
    "standardIdentifier" : "uniprot:C8CKA0",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "IFN-alpha-9" ],
    "parents" : [ 10483272 ],
    "children" : [ ]
  }, {
    "dbId" : 9734438,
    "stId" : "R-ALL-9734438",
    "displayName" : "peginterferon alfa-2a [extracellular region]",
    "schemaClass" : "ProteinDrug",
    "speciesId" : 0,
    "identifier" : "47205819",
    "standardIdentifier" : "pubchem.substance:47205819",
    "parents" : [ 9696187 ],
    "children" : [ ]
  }, {
    "dbId" : 10483242,
    "stId" : "R-SSC-877339-6",
    "displayName" : "IFN-alpha-4 [extracellular region]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 49633,
    "identifier" : "C8CK95",
    "standardIdentifier" : "uniprot:C8CK95",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "IFN-alpha-4" ],
    "parents" : [ 10483272 ],
    "children" : [ ]
  }, {
    "dbId" : 10558999,
    "stId" : "R-SSC-9833482",
    "displayName" : "PKR-mediated signaling",
    "schemaClass" : "Pathway",
    "speciesId" : 49633,
    "diagramIds" : [ 103956 ]
  }, {
    "dbId" : 10479912,
    "stId" : "R-SSC-451898",
    "displayName" : "JAK1 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 49633,
    "identifier" : "A0A286ZLI2",
    "standardIdentifier" : "uniprot:A0A286ZLI2",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 10483358 ],
    "children" : [ ]
  }, {
    "dbId" : 9734435,
    "stId" : "R-ALL-9734435",
    "displayName" : "peginterferon beta-1a [extracellular region]",
    "schemaClass" : "ProteinDrug",
    "speciesId" : 0,
    "identifier" : "7637",
    "standardIdentifier" : "iuphar.ligand:7637",
    "parents" : [ 9696187 ],
    "children" : [ ]
  }, {
    "dbId" : 10483238,
    "stId" : "R-SSC-877339-5",
    "displayName" : "LOC100737904 [extracellular region]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 49633,
    "identifier" : "A0A8W4FN82",
    "standardIdentifier" : "uniprot:A0A8W4FN82",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "LOC100737904" ],
    "parents" : [ 10483272 ],
    "children" : [ ]
  }, {
    "dbId" : 113592,
    "stId" : "R-ALL-113592",
    "displayName" : "ATP [cytosol]",
    "schemaClass" : "SimpleEntity",
    "speciesId" : 0,
    "diagramIds" : [ 103876, 103892, 103863, 103868 ],
    "identifier" : "30616",
    "standardIdentifier" : "chebi:30616",
    "referenceType" : "ReferenceMolecule",
    "parents" : [ ],
    "children" : [ ]
  }, {
    "dbId" : 29370,
    "stId" : "R-ALL-29370",
    "displayName" : "ADP [cytosol]",
    "schemaClass" : "SimpleEntity",
    "speciesId" : 0,
    "diagramIds" : [ 103877, 103893, 103865, 103870 ],
    "identifier" : "456216",
    "standardIdentifier" : "chebi:456216",
    "referenceType" : "ReferenceMolecule",
    "parents" : [ ],
    "children" : [ ]
  }, {
    "dbId" : 29372,
    "stId" : "R-ALL-29372",
    "displayName" : "Pi [cytosol]",
    "schemaClass" : "SimpleEntity",
    "speciesId" : 0,
    "diagramIds" : [ 103904, 103909, 103914 ],
    "identifier" : "43474",
    "standardIdentifier" : "chebi:43474",
    "referenceType" : "ReferenceMolecule",
    "parents" : [ ],
    "children" : [ ]
  }, {
    "dbId" : 10483234,
    "stId" : "R-SSC-877339-4",
    "displayName" : "IFNA10 [extracellular region]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 49633,
    "identifier" : "A0A8W4F7R3",
    "standardIdentifier" : "uniprot:A0A8W4F7R3",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 10483272 ],
    "children" : [ ]
  }, {
    "dbId" : 10483294,
    "stId" : "R-SSC-877349-11",
    "displayName" : "IFN-alpha-2 [extracellular region]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 49633,
    "identifier" : "Q304W0",
    "standardIdentifier" : "uniprot:Q304W0",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "IFN-alpha-2" ],
    "parents" : [ 10483300 ],
    "children" : [ ]
  }, {
    "dbId" : 10483292,
    "stId" : "R-SSC-877349-10",
    "displayName" : "LOC100156936 [extracellular region]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 49633,
    "identifier" : "Q1KNJ3",
    "standardIdentifier" : "uniprot:Q1KNJ3",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "LOC100156936" ],
    "parents" : [ 10483300 ],
    "children" : [ ]
  }, {
    "dbId" : 10483290,
    "stId" : "R-SSC-877349-9",
    "displayName" : "IFN-alpha-17 [extracellular region]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 49633,
    "identifier" : "C8CKA8",
    "standardIdentifier" : "uniprot:C8CKA8",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "IFN-alpha-17" ],
    "parents" : [ 10483300 ],
    "children" : [ ]
  }, {
    "dbId" : 10483288,
    "stId" : "R-SSC-877349-8",
    "displayName" : "IFN-alpha-13 [extracellular region]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 49633,
    "identifier" : "C8CKA4",
    "standardIdentifier" : "uniprot:C8CKA4",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "IFN-alpha-13" ],
    "parents" : [ 10483300 ],
    "children" : [ ]
  }, {
    "dbId" : 10483286,
    "stId" : "R-SSC-877349-7",
    "displayName" : "IFN-alpha-9 [extracellular region]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 49633,
    "identifier" : "C8CKA0",
    "standardIdentifier" : "uniprot:C8CKA0",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "IFN-alpha-9" ],
    "parents" : [ 10483300 ],
    "children" : [ ]
  }, {
    "dbId" : 10483284,
    "stId" : "R-SSC-877349-6",
    "displayName" : "IFN-alpha-4 [extracellular region]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 49633,
    "identifier" : "C8CK95",
    "standardIdentifier" : "uniprot:C8CK95",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "IFN-alpha-4" ],
    "parents" : [ 10483300 ],
    "children" : [ ]
  }, {
    "dbId" : 10483282,
    "stId" : "R-SSC-877349-5",
    "displayName" : "LOC100737904 [extracellular region]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 49633,
    "identifier" : "A0A8W4FN82",
    "standardIdentifier" : "uniprot:A0A8W4FN82",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "LOC100737904" ],
    "parents" : [ 10483300 ],
    "children" : [ ]
  }, {
    "dbId" : 10483280,
    "stId" : "R-SSC-877349-4",
    "displayName" : "IFNA2 [extracellular region]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 49633,
    "identifier" : "A0A8W4F7R3",
    "standardIdentifier" : "uniprot:A0A8W4F7R3",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 10483300 ],
    "children" : [ ]
  }, {
    "dbId" : 10483278,
    "stId" : "R-SSC-877349-3",
    "displayName" : "IFNA2 [extracellular region]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 49633,
    "identifier" : "A0A5G2QHB7",
    "standardIdentifier" : "uniprot:A0A5G2QHB7",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 10483300 ],
    "children" : [ ]
  }, {
    "dbId" : 10483276,
    "stId" : "R-SSC-877349-2",
    "displayName" : "IFN-ALPHA-8 [extracellular region]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 49633,
    "identifier" : "A0A287BCH3",
    "standardIdentifier" : "uniprot:A0A287BCH3",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "IFN-ALPHA-8" ],
    "parents" : [ 10483300 ],
    "children" : [ ]
  }, {
    "dbId" : 10483274,
    "stId" : "R-SSC-877349",
    "displayName" : "IFN-ALPHA-15 [extracellular region]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 49633,
    "identifier" : "A0A287AUX7",
    "standardIdentifier" : "uniprot:A0A287AUX7",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "IFN-ALPHA-15" ],
    "parents" : [ 10483300 ],
    "children" : [ ]
  }, {
    "dbId" : 10483272,
    "stId" : "R-SSC-877339-14",
    "displayName" : "Homologues of IFNA10 [extracellular region]",
    "schemaClass" : "DefinedSet",
    "speciesId" : 49633,
    "parents" : [ 10483306 ],
    "children" : [ 10483266, 10483234, 10483270, 10483238, 10483242, 10483246, 10483250, 10483254, 10483222, 10483258, 10483226, 10483262, 10483230 ]
  }, {
    "dbId" : 10482760,
    "stId" : "R-SSC-877267",
    "displayName" : "SOCS-1 and SOCS-3 [cytosol]",
    "schemaClass" : "DefinedSet",
    "speciesId" : 49633,
    "parents" : [ 10483422 ],
    "children" : [ 10482754, 10482758 ]
  }, {
    "dbId" : 10483270,
    "stId" : "R-SSC-877339-13",
    "displayName" : "IFN-alpha-1 [extracellular region]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 49633,
    "identifier" : "Q6VAB8",
    "standardIdentifier" : "uniprot:Q6VAB8",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "IFN-alpha-1" ],
    "parents" : [ 10483272 ],
    "children" : [ ]
  }, {
    "dbId" : 10482758,
    "stId" : "R-SSC-873794",
    "displayName" : "SOCS3 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 49633,
    "identifier" : "E5EZY0",
    "standardIdentifier" : "uniprot:E5EZY0",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "SOCS3" ],
    "parents" : [ 10482760 ],
    "children" : [ ]
  }, {
    "dbId" : 10483266,
    "stId" : "R-SSC-877339-12",
    "displayName" : "IFN-alpha-1 [extracellular region]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 49633,
    "identifier" : "Q304W2",
    "standardIdentifier" : "uniprot:Q304W2",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "IFN-alpha-1" ],
    "parents" : [ 10483272 ],
    "children" : [ ]
  }, {
    "dbId" : 10482754,
    "stId" : "R-SSC-204910",
    "displayName" : "SOCS1 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 49633,
    "identifier" : "E7CR04",
    "standardIdentifier" : "uniprot:E7CR04",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "SOCS1" ],
    "parents" : [ 10482760 ],
    "children" : [ ]
  }, {
    "dbId" : 10483521,
    "stId" : "R-SSC-912690",
    "displayName" : "IFNAR2c:UBP43 [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 49633,
    "diagramIds" : [ 103901 ],
    "parents" : [ ],
    "children" : [ 10483332, 10483519 ]
  }, {
    "dbId" : 10483326,
    "stId" : "R-SSC-909683",
    "displayName" : "phospho-STAT2 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 49633,
    "identifier" : "O02799",
    "standardIdentifier" : "uniprot:O02799",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "STAT2" ],
    "parents" : [ 10488608, 10483376, 10483328 ],
    "children" : [ ]
  }, {
    "dbId" : 10483582,
    "stId" : "R-SSC-913526",
    "displayName" : "p-Y701-STAT1 dimer [nucleoplasm]",
    "schemaClass" : "Complex",
    "speciesId" : 49633,
    "diagramIds" : [ 103897 ],
    "parents" : [ ],
    "children" : [ 10483386 ]
  }, {
    "dbId" : 10483580,
    "stId" : "R-SSC-9757480",
    "displayName" : "p-Y701-STAT1:KPNA1:KPNB1 [cytosol]",
    "schemaClass" : "Complex",
    "speciesId" : 49633,
    "diagramIds" : [ 103896 ],
    "parents" : [ 10548059 ],
    "children" : [ 10469090, 10469094, 10482794 ]
  }, {
    "dbId" : 10483321,
    "stId" : "R-SSC-909675",
    "displayName" : "phospho-IFNAR1 [plasma membrane]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 49633,
    "identifier" : "A0A480S426",
    "standardIdentifier" : "uniprot:A0A480S426",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "IFNAR1" ],
    "parents" : [ 10488610, 10483422, 10483343, 10483349, 10483398, 10483328 ],
    "children" : [ ]
  }, {
    "dbId" : 10512200,
    "stId" : "R-SSC-5223312",
    "displayName" : "RNASEL [mitochondrial matrix]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 49633,
    "identifier" : "A0A286ZPJ7",
    "standardIdentifier" : "uniprot:A0A286ZPJ7",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "RNASEL" ],
    "parents" : [ 10512202 ],
    "children" : [ ]
  }, {
    "dbId" : 10512202,
    "stId" : "R-SSC-5357403",
    "displayName" : "RNASEL dimer [mitochondrial matrix]",
    "schemaClass" : "Complex",
    "speciesId" : 49633,
    "diagramIds" : [ 103918 ],
    "parents" : [ 10512208 ],
    "children" : [ 10512200 ]
  }, {
    "dbId" : 10483315,
    "stId" : "R-SSC-909682",
    "displayName" : "phospho-p-Y1054,Y1055-TYK2 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 49633,
    "identifier" : "F1S3L9",
    "standardIdentifier" : "uniprot:F1S3L9",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 10488610, 10483422, 10483417, 10483343, 10483349, 10483398, 10483328 ],
    "children" : [ ]
  }, {
    "dbId" : 10512206,
    "stId" : "R-SSC-5216010",
    "displayName" : "ABCE1 [mitochondrial matrix]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 49633,
    "diagramIds" : [ 103917 ],
    "identifier" : "A0A5G2QNL9",
    "standardIdentifier" : "uniprot:A0A5G2QNL9",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "ABCE1" ],
    "parents" : [ 10512208 ],
    "children" : [ ]
  }, {
    "dbId" : 10483312,
    "stId" : "R-SSC-909690",
    "displayName" : "IFN alpha/beta (IFNA/B) [extracellular region]",
    "schemaClass" : "DefinedSet",
    "speciesId" : 49633,
    "diagramIds" : [ 103853 ],
    "parents" : [ 10488612, 10483360, 10483345, 10483351, 10483400, 10483338 ],
    "children" : [ 10483306, 10483310 ]
  }, {
    "dbId" : 10512208,
    "stId" : "R-SSC-5223322",
    "displayName" : "ABCE1:RNASEL dimer [mitochondrial matrix]",
    "schemaClass" : "Complex",
    "speciesId" : 49633,
    "diagramIds" : [ 103919 ],
    "parents" : [ ],
    "children" : [ 10512206, 10512202 ]
  }, {
    "dbId" : 10483310,
    "stId" : "R-SSC-877351",
    "displayName" : "IFNB1 [extracellular region]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 49633,
    "identifier" : "Q29412",
    "standardIdentifier" : "uniprot:Q29412",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "IFNB1" ],
    "parents" : [ 10483312 ],
    "children" : [ ]
  }, {
    "dbId" : 10548051,
    "stId" : "R-SSC-9710957",
    "displayName" : "p-STAT1 dimer, ISGF3 [cytosol]",
    "schemaClass" : "DefinedSet",
    "speciesId" : 49633,
    "diagramIds" : [ 103928 ],
    "parents" : [ ],
    "children" : [ 10483378, 10482794 ]
  }, {
    "dbId" : 10483306,
    "stId" : "R-SSC-909688",
    "displayName" : "IFNA [extracellular region]",
    "schemaClass" : "DefinedSet",
    "speciesId" : 49633,
    "parents" : [ 10483312 ],
    "children" : [ 10483300, 10483302, 10483272 ]
  }, {
    "dbId" : 10482794,
    "stId" : "R-SSC-913524",
    "displayName" : "p-Y701-STAT1-1 dimer [cytosol]",
    "schemaClass" : "Complex",
    "speciesId" : 49633,
    "diagramIds" : [ 103894 ],
    "parents" : [ 10548051, 10483580, 10548053 ],
    "children" : [ 10482792 ]
  }, {
    "dbId" : 10548053,
    "stId" : "R-SSC-9757485",
    "displayName" : "p-Y701-STAT1:KPNA1 [cytosol]",
    "schemaClass" : "Complex",
    "speciesId" : 49633,
    "parents" : [ 10548055 ],
    "children" : [ 10469090, 10482794 ]
  }, {
    "dbId" : 10482792,
    "stId" : "R-SSC-873791",
    "displayName" : "phospho-STAT1 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 49633,
    "identifier" : "G9BFT9",
    "standardIdentifier" : "uniprot:G9BFT9",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "STAT1" ],
    "parents" : [ 10483376, 10482794 ],
    "children" : [ ]
  }, {
    "dbId" : 10548055,
    "stId" : "R-SSC-9757478",
    "displayName" : "p-STAT1 dimer:KPNA1 [cytosol]",
    "schemaClass" : "DefinedSet",
    "speciesId" : 49633,
    "diagramIds" : [ 103929 ],
    "parents" : [ ],
    "children" : [ 10483380, 10548053 ]
  }, {
    "dbId" : 10483302,
    "stId" : "R-SSC-877338",
    "displayName" : "IFN-alpha-13 [extracellular region]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 49633,
    "identifier" : "C8CKA4",
    "standardIdentifier" : "uniprot:C8CKA4",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "IFN-alpha-13" ],
    "parents" : [ 10483306 ],
    "children" : [ ]
  }, {
    "dbId" : 10483300,
    "stId" : "R-SSC-877349-14",
    "displayName" : "Homologues of IFNA2 [extracellular region]",
    "schemaClass" : "DefinedSet",
    "speciesId" : 49633,
    "parents" : [ 10483306 ],
    "children" : [ 10483296, 10483298, 10483274, 10483276, 10483278, 10483280, 10483282, 10483284, 10483286, 10483288, 10483290, 10483292, 10483294 ]
  }, {
    "dbId" : 10548059,
    "stId" : "R-SSC-9757476",
    "displayName" : "p-STAT1 dimer:KPNA1:KPNB1 [cytosol]",
    "schemaClass" : "DefinedSet",
    "speciesId" : 49633,
    "diagramIds" : [ 103932 ],
    "parents" : [ ],
    "children" : [ 10483382, 10483580 ]
  }, {
    "dbId" : 10483298,
    "stId" : "R-SSC-877349-13",
    "displayName" : "IFN-alpha-1 [extracellular region]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 49633,
    "identifier" : "Q6VAB8",
    "standardIdentifier" : "uniprot:Q6VAB8",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "IFN-alpha-1" ],
    "parents" : [ 10483300 ],
    "children" : [ ]
  }, {
    "dbId" : 10482786,
    "stId" : "R-SSC-380745",
    "displayName" : "STAT1 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 49633,
    "diagramIds" : [ 103891, 103935 ],
    "identifier" : "G9BFT9",
    "standardIdentifier" : "uniprot:G9BFT9",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "STAT1" ],
    "parents" : [ 10488608 ],
    "children" : [ ]
  }, {
    "dbId" : 10483296,
    "stId" : "R-SSC-877349-12",
    "displayName" : "IFN-alpha-1 [extracellular region]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 49633,
    "identifier" : "Q304W2",
    "standardIdentifier" : "uniprot:Q304W2",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "IFN-alpha-1" ],
    "parents" : [ 10483300 ],
    "children" : [ ]
  } ],
  "edges" : [ {
    "dbId" : 10547009,
    "stId" : "R-SSC-9678935",
    "displayName" : "IFNAR2:JAK1:STAT2 binds JAK1,2 inhibitors",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "inputs" : [ 9678984, 10483358 ],
    "outputs" : [ 10483362 ],
    "efs" : [ ],
    "diagramIds" : [ 103920 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10483355,
    "stId" : "R-SSC-909719",
    "displayName" : "Recruitment of STAT2 to p-IFNAR1",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "preceding" : [ 10483430 ],
    "following" : [ 10483433 ],
    "inputs" : [ 10483347, 10483334 ],
    "outputs" : [ 10483351 ],
    "efs" : [ ],
    "inhibitors" : [ 10483353 ],
    "diagramIds" : [ 103871 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10547367,
    "stId" : "R-SSC-9696179",
    "displayName" : "IFNAR2:JAK1:STAT2 binds type 1 interferon analogs",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "inputs" : [ 9696187, 10483358 ],
    "outputs" : [ 10483364 ],
    "efs" : [ ],
    "diagramIds" : [ 103924 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10488615,
    "stId" : "R-SSC-997309",
    "displayName" : "Dephosphorylation of STAT1 by SHP2",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "inputs" : [ 29356, 10483400 ],
    "outputs" : [ 29372, 10488612 ],
    "catalysts" : [ 10459101 ],
    "efs" : [ ],
    "diagramIds" : [ 103911 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10483415,
    "stId" : "R-SSC-909725",
    "displayName" : "Interaction of IRF9 with p-STAT2:p-STAT1",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "preceding" : [ 10483402 ],
    "following" : [ 10548057 ],
    "inputs" : [ 10483376, 10483372 ],
    "outputs" : [ 10483378 ],
    "efs" : [ ],
    "diagramIds" : [ 103882 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10546985,
    "stId" : "R-SSC-9678737",
    "displayName" : "IFNAR1:TYK2 binds TYK2 inhibitors",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "inputs" : [ 9678619, 10483406 ],
    "outputs" : [ 10483410 ],
    "efs" : [ ],
    "diagramIds" : [ 103922 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10483412,
    "stId" : "R-SSC-909724",
    "displayName" : "Recruitment of IFNAR1",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "preceding" : [ 10483366 ],
    "following" : [ 10483426 ],
    "inputs" : [ 10483360, 10483406 ],
    "outputs" : [ 10483408 ],
    "efs" : [ ],
    "inhibitors" : [ 10483410 ],
    "diagramIds" : [ 103858 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10488619,
    "stId" : "R-SSC-997311",
    "displayName" : "Dephosphorylation of TYK2 by PTP1B",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "preceding" : [ 10483426 ],
    "following" : [ 10488622 ],
    "inputs" : [ 29356, 10483419 ],
    "outputs" : [ 29372, 10488617 ],
    "catalysts" : [ 10471962 ],
    "efs" : [ ],
    "diagramIds" : [ 103902 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10488622,
    "stId" : "R-SSC-997314",
    "displayName" : "Dephosphorylation of JAK1 by SHP1",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "preceding" : [ 10488619 ],
    "inputs" : [ 29356, 10488617 ],
    "outputs" : [ 10483408, 29372 ],
    "catalysts" : [ 10468485 ],
    "efs" : [ ],
    "diagramIds" : [ 103907 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10483341,
    "stId" : "R-SSC-909718",
    "displayName" : "Formation of p-STAT1 homodimer",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "preceding" : [ 10483433 ],
    "following" : [ 10548057 ],
    "inputs" : [ 10482786, 113592 ],
    "outputs" : [ 29370, 10482794 ],
    "catalysts" : [ 10483338 ],
    "efs" : [ ],
    "diagramIds" : [ 103890 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10512210,
    "stId" : "R-SSC-5223305",
    "displayName" : "ABCE1 binds RNASEL, inhibiting it",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "inputs" : [ 10512206, 10512202 ],
    "outputs" : [ 10512208 ],
    "efs" : [ ],
    "diagramIds" : [ 103916 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10483402,
    "stId" : "R-SSC-909722",
    "displayName" : "Release of p-STAT2:p-STAT1 dimer",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "following" : [ 10483415 ],
    "inputs" : [ 10483400 ],
    "outputs" : [ 10483376, 10483347 ],
    "efs" : [ ],
    "diagramIds" : [ 103879 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10483433,
    "stId" : "R-SSC-909732",
    "displayName" : "Phosphorylation of STAT2",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "preceding" : [ 10483355 ],
    "following" : [ 10483341 ],
    "inputs" : [ 113592, 10483351 ],
    "outputs" : [ 29370, 10483338 ],
    "catalysts" : [ 10483351 ],
    "efs" : [ ],
    "diagramIds" : [ 103875 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10483366,
    "stId" : "R-SSC-909720",
    "displayName" : "IFN alpha/beta binds to IFNAR2",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "following" : [ 10483412 ],
    "inputs" : [ 10483312, 10483358 ],
    "outputs" : [ 10483360 ],
    "efs" : [ ],
    "inhibitors" : [ 10483362 ],
    "activators" : [ 10483364 ],
    "diagramIds" : [ 103852 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10483430,
    "stId" : "R-SSC-909730",
    "displayName" : "Phosphorylation of INFAR1 by TYK2",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "preceding" : [ 10483426 ],
    "following" : [ 10483355 ],
    "inputs" : [ 113592, 10483419 ],
    "outputs" : [ 10483347, 29370 ],
    "catalysts" : [ 10483419 ],
    "efs" : [ ],
    "diagramIds" : [ 103867 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10548057,
    "stId" : "R-SSC-9710959",
    "displayName" : "p-STAT1 dimer binds KPNA1",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "preceding" : [ 10483415, 10483341 ],
    "following" : [ 10548061 ],
    "inputs" : [ 10469090, 10548051 ],
    "outputs" : [ 10548055 ],
    "efs" : [ ],
    "diagramIds" : [ 103926 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10483396,
    "stId" : "R-SSC-909721",
    "displayName" : "Translocation of ISGF3 complex to nucleus",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "preceding" : [ 10548061 ],
    "inputs" : [ 10483382 ],
    "outputs" : [ 10483394, 10469112, 10469114 ],
    "efs" : [ ],
    "diagramIds" : [ 103885 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10483523,
    "stId" : "R-SSC-912685",
    "displayName" : "UBP43 binds IFNAR2 and prevents JAK1 interaction",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "inputs" : [ 10483332, 10483519 ],
    "outputs" : [ 10483521 ],
    "efs" : [ ],
    "diagramIds" : [ 103898 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10483426,
    "stId" : "R-SSC-909729",
    "displayName" : "Activation of JAK kinases",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "preceding" : [ 10483412 ],
    "following" : [ 10488619, 10483430 ],
    "inputs" : [ 10483408, 113592 ],
    "outputs" : [ 29370, 10483419 ],
    "catalysts" : [ 10483408 ],
    "efs" : [ ],
    "inhibitors" : [ 10483424 ],
    "diagramIds" : [ 103862 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10548061,
    "stId" : "R-SSC-9710963",
    "displayName" : "p-STAT1dimer:KPNA1 binds KPNB1",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "preceding" : [ 10548057 ],
    "following" : [ 10483584, 10483396 ],
    "inputs" : [ 10469094, 10548055 ],
    "outputs" : [ 10548059 ],
    "efs" : [ ],
    "diagramIds" : [ 103930 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10483584,
    "stId" : "R-SSC-913529",
    "displayName" : "Translocation of p-STAT1:p-STAT1 dimer to nucleus",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "preceding" : [ 10548061 ],
    "inputs" : [ 10483580 ],
    "outputs" : [ 10469112, 10469114, 10483582 ],
    "efs" : [ ],
    "diagramIds" : [ 103895 ],
    "entityFunctionalStatus" : [ ]
  } ],
  "subpathways" : [ {
    "dbId" : 10557557,
    "stId" : "R-SSC-912694",
    "displayName" : "Regulation of IFNA/IFNB signaling",
    "events" : [ 10488615, 10488619, 10483523, 10488622 ]
  } ]
}