{ "dbId" : 10556865, "stId" : "R-SSC-202403", "speciesName" : "Sus scrofa", "nodes" : [ { "dbId" : 10471070, "stId" : "R-SSC-197954", "displayName" : "NCK1 [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49633, "diagramIds" : [ 113438 ], "identifier" : "I3LP69", "standardIdentifier" : "uniprot:I3LP69", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "NCK1" ], "parents" : [ 10478341 ], "children" : [ ] }, { "dbId" : 10466972, "stId" : "R-SSC-8866028", "displayName" : "CD101 [plasma membrane]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49633, "diagramIds" : [ 113338 ], "identifier" : "K7GLC3", "standardIdentifier" : "uniprot:K7GLC3", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "CD101" ], "parents" : [ ], "children" : [ ] }, { "dbId" : 202247, "stId" : "R-ALL-202247", "displayName" : "PI(3,4)P2 [plasma membrane]", "schemaClass" : "SimpleEntity", "speciesId" : 0, "diagramIds" : [ 113363 ], "identifier" : "16152", "standardIdentifier" : "chebi:16152", "referenceType" : "ReferenceMolecule", "parents" : [ 202277 ], "children" : [ ] }, { "dbId" : 10466967, "stId" : "R-SSC-202282", "displayName" : "ZAP-70 and ITK tyrosine kinases [plasma membrane]", "schemaClass" : "DefinedSet", "speciesId" : 49633, "diagramIds" : [ 113337 ], "parents" : [ ], "children" : [ 10466965, 10466841 ] }, { "dbId" : 10466965, "stId" : "R-SSC-202359", "displayName" : "ITK:p-Y113,128,145-SLP-76:GADS:LAT [plasma membrane]", "schemaClass" : "Complex", "speciesId" : 49633, "diagramIds" : [ 113326 ], "parents" : [ 10466967 ], "children" : [ 10466963, 10466905 ] }, { "dbId" : 10466963, "stId" : "R-SSC-202319", "displayName" : "ITK [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49633, "diagramIds" : [ 113325 ], "identifier" : "A0A8D0MIS4", "standardIdentifier" : "uniprot:A0A8D0MIS4", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "ITK" ], "parents" : [ 10466965 ], "children" : [ ] }, { "dbId" : 10466959, "stId" : "R-SSC-202193", "displayName" : "Phosphorylated PLC-gamma1 bound to LAT or SLP-76 [plasma membrane]", "schemaClass" : "DefinedSet", "speciesId" : 49633, "diagramIds" : [ 113335 ], "parents" : [ ], "children" : [ 10466955, 10466957 ] }, { "dbId" : 10466957, "stId" : "R-SSC-202302", "displayName" : "phosphorylated PLC-gamma1 bound to SLP-76 [plasma membrane]", "schemaClass" : "Complex", "speciesId" : 49633, "diagramIds" : [ 113343 ], "parents" : [ 10466959 ], "children" : [ 10466953, 10466905 ] }, { "dbId" : 10466955, "stId" : "R-SSC-202310", "displayName" : "phosphorylated PLC-gamma1 bound to LAT [plasma membrane]", "schemaClass" : "Complex", "speciesId" : 49633, "diagramIds" : [ 113340 ], "parents" : [ 10466959 ], "children" : [ 10466866, 10466953 ] }, { "dbId" : 10466953, "stId" : "R-SSC-202357", "displayName" : "phospho-PLCG1 [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49633, "diagramIds" : [ 113341 ], "identifier" : "F1SDV6", "standardIdentifier" : "uniprot:F1SDV6", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "PLCG1" ], "parents" : [ 10466957, 10466955 ], "children" : [ ] }, { "dbId" : 10474630, "stId" : "R-SSC-390765", "displayName" : "PAK1,2,3 [cytosol]", "schemaClass" : "DefinedSet", "speciesId" : 49633, "diagramIds" : [ 113441 ], "parents" : [ 10478343 ], "children" : [ 10474624, 10474618 ] }, { "dbId" : 10466948, "stId" : "R-SSC-202318", "displayName" : "PLC-gamma1 bound to LAT or SLP-76 [plasma membrane]", "schemaClass" : "DefinedSet", "speciesId" : 49633, "diagramIds" : [ 113333 ], "parents" : [ ], "children" : [ 10466946, 10466868 ] }, { "dbId" : 10466946, "stId" : "R-SSC-202279", "displayName" : "PLCG1:p-3Y-SLP-76:Gads:LAT [plasma membrane]", "schemaClass" : "Complex", "speciesId" : 49633, "diagramIds" : [ 113329 ], "parents" : [ 10466948 ], "children" : [ 10466857, 10466905 ] }, { "dbId" : 10474624, "stId" : "R-SSC-211604", "displayName" : "PAK2 [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49633, "identifier" : "F1SQW0", "standardIdentifier" : "uniprot:F1SQW0", "referenceType" : "ReferenceGeneProduct", "parents" : [ 10474630 ], "children" : [ ] }, { "dbId" : 10467006, "stId" : "R-SSC-202161", "displayName" : "CARD11 [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49633, "diagramIds" : [ 113384 ], "identifier" : "A0A287A3X6", "standardIdentifier" : "uniprot:A0A287A3X6", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "CARD11" ], "parents" : [ 10467008 ], "children" : [ ] }, { "dbId" : 202277, "stId" : "R-ALL-202277", "displayName" : "PIP3, PI(3,4)P2 [plasma membrane]", "schemaClass" : "DefinedSet", "speciesId" : 0, "diagramIds" : [ 113367 ], "parents" : [ 10466714 ], "children" : [ 179838, 202247 ] }, { "dbId" : 10466995, "stId" : "R-SSC-202269", "displayName" : "Activated PLC gamma1 bound to PIP2 [plasma membrane]", "schemaClass" : "Complex", "speciesId" : 49633, "diagramIds" : [ 113346 ], "parents" : [ ], "children" : [ 10466993, 179856 ] }, { "dbId" : 10466993, "stId" : "R-SSC-167679", "displayName" : "phospho-PLCG1 [plasma membrane]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49633, "identifier" : "F1SDV6", "standardIdentifier" : "uniprot:F1SDV6", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "PLCG1" ], "parents" : [ 10466995, 10467017 ], "children" : [ ] }, { "dbId" : 10466982, "stId" : "R-SSC-202187", "displayName" : "PKC-theta (open): DAG [plasma membrane]", "schemaClass" : "Complex", "speciesId" : 49633, "diagramIds" : [ 113373 ], "parents" : [ ], "children" : [ 10466980, 112275 ] }, { "dbId" : 10466980, "stId" : "R-SSC-202346", "displayName" : "PRKCQ [plasma membrane]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49633, "identifier" : "A0A4X1T8P0", "standardIdentifier" : "uniprot:A0A4X1T8P0", "referenceType" : "ReferenceGeneProduct", "parents" : [ 10466982 ], "children" : [ ] }, { "dbId" : 10534624, "stId" : "R-SSC-8855376", "displayName" : "PTPN22:CSK [cytosol]", "schemaClass" : "Complex", "speciesId" : 49633, "diagramIds" : [ 113453 ], "parents" : [ ], "children" : [ 10466925, 10533986 ] }, { "dbId" : 10467039, "stId" : "R-SSC-202475", "displayName" : "Bcl10 trimer bound to CARMA1 trimer [plasma membrane]", "schemaClass" : "Complex", "speciesId" : 49633, "diagramIds" : [ 113403 ], "parents" : [ 10467047 ], "children" : [ 10467030, 10467037 ] }, { "dbId" : 10467037, "stId" : "R-SSC-202488", "displayName" : "phospho-BCL10 [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49633, "diagramIds" : [ 113402 ], "identifier" : "A7XP20", "standardIdentifier" : "uniprot:A7XP20", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "BCL10" ], "parents" : [ 10467063, 10467039 ], "children" : [ ] }, { "dbId" : 10459352, "stId" : "R-SSC-168151", "displayName" : "NFKBIA [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49633, "identifier" : "Q08353", "standardIdentifier" : "uniprot:Q08353", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "NFKBIA" ], "parents" : [ 10464134 ], "children" : [ ] }, { "dbId" : 10467030, "stId" : "R-SSC-202445", "displayName" : "CARMA1 trimer [plasma membrane]", "schemaClass" : "Complex", "speciesId" : 49633, "diagramIds" : [ 113392 ], "parents" : [ 10467061, 10467063, 10467039 ], "children" : [ 10466714, 10467023 ] }, { "dbId" : 10463957, "stId" : "R-SSC-168114", "displayName" : "IKBKB [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49633, "identifier" : "A0A287A5Q1", "standardIdentifier" : "uniprot:A0A287A5Q1", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "IKBKB" ], "parents" : [ 10467076 ], "children" : [ ] }, { "dbId" : 10467025, "stId" : "R-SSC-202440", "displayName" : "Activated CARMA1 [plasma membrane]", "schemaClass" : "Complex", "speciesId" : 49633, "diagramIds" : [ 113389 ], "parents" : [ ], "children" : [ 10466714, 10467023 ] }, { "dbId" : 10467023, "stId" : "R-SSC-202438", "displayName" : "phospho-CARD11 [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49633, "diagramIds" : [ 113391 ], "identifier" : "A0A287A3X6", "standardIdentifier" : "uniprot:A0A287A3X6", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "CARD11" ], "parents" : [ 10467025, 10467030 ], "children" : [ ] }, { "dbId" : 10459340, "stId" : "R-SSC-168168", "displayName" : "NFKB1 [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49633, "identifier" : "A0A287AVR3", "standardIdentifier" : "uniprot:A0A287AVR3", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "NFKB1" ], "parents" : [ 10464103 ], "children" : [ ] }, { "dbId" : 10467017, "stId" : "R-SSC-2029095", "displayName" : "p-PLCG [plasma membrane]", "schemaClass" : "DefinedSet", "speciesId" : 49633, "diagramIds" : [ 113351 ], "parents" : [ ], "children" : [ 10466993, 10467015 ] }, { "dbId" : 10459336, "stId" : "R-SSC-168172", "displayName" : "RELA [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49633, "identifier" : "F6PVF4", "standardIdentifier" : "uniprot:F6PVF4", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "RELA" ], "parents" : [ 10464103 ], "children" : [ ] }, { "dbId" : 10467015, "stId" : "R-SSC-984816", "displayName" : "phospho-PLCG2 [plasma membrane]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49633, "identifier" : "F1S475", "standardIdentifier" : "uniprot:F1S475", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "PLCG2" ], "parents" : [ 10467017 ], "children" : [ ] }, { "dbId" : 10467008, "stId" : "R-SSC-202349", "displayName" : "CARMA1 bound to PDK1 [plasma membrane]", "schemaClass" : "Complex", "speciesId" : 49633, "diagramIds" : [ 113385 ], "parents" : [ ], "children" : [ 10466714, 10467006 ] }, { "dbId" : 10465023, "stId" : "R-SSC-198176", "displayName" : "T-cell receptor alpha chain V region PY14 precursor [plasma membrane]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49633, "identifier" : "A0A286ZYJ0", "standardIdentifier" : "uniprot:A0A286ZYJ0", "referenceType" : "ReferenceGeneProduct", "parents" : [ 10465029 ], "children" : [ ] }, { "dbId" : 10478331, "stId" : "R-SSC-430124", "displayName" : "p-SLP-76:ADAP [cytosol]", "schemaClass" : "Complex", "speciesId" : 49633, "diagramIds" : [ 113436 ], "parents" : [ ], "children" : [ 10475011, 10466903 ] }, { "dbId" : 10459386, "stId" : "R-SSC-202506", "displayName" : "phospho-IKBKB [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49633, "identifier" : "A0A287A5Q1", "standardIdentifier" : "uniprot:A0A287A5Q1", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "IKBKB" ], "parents" : [ 10467111, 10467078 ], "children" : [ ] }, { "dbId" : 10467063, "stId" : "R-SSC-202480", "displayName" : "Phosphorylated Bcl10 bound to CARMA1 and RIP2 [plasma membrane]", "schemaClass" : "Complex", "speciesId" : 49633, "diagramIds" : [ 113399 ], "parents" : [ ], "children" : [ 10467030, 10467037 ] }, { "dbId" : 10467061, "stId" : "R-SSC-202454", "displayName" : "Bcl10 bound to CARMA1 [plasma membrane]", "schemaClass" : "Complex", "speciesId" : 49633, "diagramIds" : [ 113395 ], "parents" : [ ], "children" : [ 10467059, 10467030 ] }, { "dbId" : 10467059, "stId" : "R-SSC-202447", "displayName" : "BCL10 [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49633, "diagramIds" : [ 113394 ], "identifier" : "A7XP20", "standardIdentifier" : "uniprot:A7XP20", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "BCL10" ], "parents" : [ 10467061 ], "children" : [ ] }, { "dbId" : 10467054, "stId" : "R-SSC-202456", "displayName" : "Ub-TRAF6 trimer bound to CBM complex [plasma membrane]", "schemaClass" : "Complex", "speciesId" : 49633, "diagramIds" : [ 113413 ], "parents" : [ 10467092 ], "children" : [ 10467047, 10467052 ] }, { "dbId" : 10459374, "stId" : "R-SSC-168108", "displayName" : "IKBKG [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49633, "identifier" : "A9QT41", "standardIdentifier" : "uniprot:A9QT41", "referenceType" : "ReferenceGeneProduct", "parents" : [ 10467078, 10467076 ], "children" : [ ] }, { "dbId" : 10467052, "stId" : "R-SSC-2685681", "displayName" : "TRAF6 [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49633, "identifier" : "A7XUJ6", "standardIdentifier" : "uniprot:A7XUJ6", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "TRAF6" ], "parents" : [ 10467054 ], "children" : [ ] }, { "dbId" : 10467049, "stId" : "R-SSC-202471", "displayName" : "TRAF6 trimer bound to CBM complex [plasma membrane]", "schemaClass" : "Complex", "speciesId" : 49633, "diagramIds" : [ 113409 ], "parents" : [ ], "children" : [ 10459233, 10467047 ] }, { "dbId" : 10467047, "stId" : "R-SSC-202468", "displayName" : "MALT1 trimer bound to Bcl10 and CARMA1 trimer [plasma membrane]", "schemaClass" : "Complex", "speciesId" : 49633, "diagramIds" : [ 113406 ], "parents" : [ 10467049, 10467054 ], "children" : [ 10467045, 10467039 ] }, { "dbId" : 10467045, "stId" : "R-SSC-202487", "displayName" : "MALT1 trimer [cytosol]", "schemaClass" : "Complex", "speciesId" : 49633, "diagramIds" : [ 113405 ], "parents" : [ 10467047 ], "children" : [ 10467043 ] }, { "dbId" : 10459364, "stId" : "R-SSC-177677", "displayName" : "phospho-NFKBIA [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49633, "identifier" : "Q08353", "standardIdentifier" : "uniprot:Q08353", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "NFKBIA" ], "parents" : [ 10467116 ], "children" : [ ] }, { "dbId" : 179838, "stId" : "R-ALL-179838", "displayName" : "PI(3,4,5)P3 [plasma membrane]", "schemaClass" : "SimpleEntity", "speciesId" : 0, "diagramIds" : [ 113359 ], "identifier" : "57836", "standardIdentifier" : "chebi:57836", "referenceType" : "ReferenceMolecule", "parents" : [ 202277 ], "children" : [ ] }, { "dbId" : 10467043, "stId" : "R-SSC-202461", "displayName" : "MALT1 [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49633, "identifier" : "K7GQH5", "standardIdentifier" : "uniprot:K7GQH5", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "MALT1" ], "parents" : [ 10467045 ], "children" : [ ] }, { "dbId" : 10466335, "stId" : "R-SSC-58216", "displayName" : "PRKCQ [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49633, "diagramIds" : [ 113371 ], "identifier" : "A0A4X1T8P0", "standardIdentifier" : "uniprot:A0A4X1T8P0", "referenceType" : "ReferenceGeneProduct", "parents" : [ ], "children" : [ ] }, { "dbId" : 10454046, "stId" : "R-SSC-61459", "displayName" : "PDPK1 [plasma membrane]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49633, "identifier" : "A0A287AST6", "standardIdentifier" : "uniprot:A0A287AST6", "referenceType" : "ReferenceGeneProduct", "parents" : [ 10466714 ], "children" : [ ] }, { "dbId" : 10466841, "stId" : "R-SSC-202181", "displayName" : "Activated ZAP-70 [plasma membrane]", "schemaClass" : "Complex", "speciesId" : 49633, "diagramIds" : [ 113307 ], "parents" : [ 10466967 ], "children" : [ 10466823, 10466839 ] }, { "dbId" : 10466839, "stId" : "R-SSC-202252", "displayName" : "Ghost homologue of p-Y315,Y493-ZAP70 [cytosol]", "schemaClass" : "GenomeEncodedEntity", "speciesId" : 49633, "parents" : [ 10466841 ], "children" : [ ] }, { "dbId" : 10466834, "stId" : "R-SSC-202345", "displayName" : "phospho tyrosine ZAP-70 [plasma membrane]", "schemaClass" : "Complex", "speciesId" : 49633, "diagramIds" : [ 113303 ], "parents" : [ ], "children" : [ 10466832, 10466823 ] }, { "dbId" : 10466832, "stId" : "R-SSC-202368", "displayName" : "Ghost homologue of p-Y493-ZAP70 [cytosol]", "schemaClass" : "GenomeEncodedEntity", "speciesId" : 49633, "parents" : [ 10466834 ], "children" : [ ] }, { "dbId" : 10466830, "stId" : "R-SSC-202330", "displayName" : "ZAP-70 bound to phosphorylated ITAM motifs [plasma membrane]", "schemaClass" : "Complex", "speciesId" : 49633, "diagramIds" : [ 113301 ], "parents" : [ ], "children" : [ 10466823, 10466828 ] }, { "dbId" : 179856, "stId" : "R-ALL-179856", "displayName" : "PI(4,5)P2 [plasma membrane]", "schemaClass" : "SimpleEntity", "speciesId" : 0, "diagramIds" : [ 113345, 113458, 113358 ], "identifier" : "58456", "standardIdentifier" : "chebi:58456", "referenceType" : "ReferenceMolecule", "parents" : [ 10466995 ], "children" : [ ] }, { "dbId" : 112275, "stId" : "R-ALL-112275", "displayName" : "DAGs [plasma membrane]", "schemaClass" : "SimpleEntity", "speciesId" : 0, "diagramIds" : [ 113349, 113372 ], "identifier" : "18035", "standardIdentifier" : "chebi:18035", "referenceType" : "ReferenceMolecule", "parents" : [ 10466920, 10466982, 10466913 ], "children" : [ ] }, { "dbId" : 10466828, "stId" : "R-SSC-202397", "displayName" : "Ghost homologue of ZAP70 [cytosol]", "schemaClass" : "GenomeEncodedEntity", "speciesId" : 49633, "parents" : [ 10466830 ], "children" : [ ] }, { "dbId" : 10466823, "stId" : "R-SSC-203494", "displayName" : "Antigen-bearing MHC Class II: TCR with phosphorylated ITAMs:CD4 [plasma membrane]", "schemaClass" : "Complex", "speciesId" : 49633, "diagramIds" : [ 113298 ], "parents" : [ 10466830, 10466834, 10466841 ], "children" : [ 10466721, 10466821, 10466725, 10466791 ] }, { "dbId" : 10466821, "stId" : "R-SSC-203493", "displayName" : "T-cell receptor complex with phosphorylated ITAMs [plasma membrane]", "schemaClass" : "Complex", "speciesId" : 49633, "parents" : [ 10466823 ], "children" : [ 10466819, 10466803, 10466809, 10465051 ] }, { "dbId" : 10464773, "stId" : "R-SSC-168104", "displayName" : "CHUK [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49633, "identifier" : "F1S8V5", "standardIdentifier" : "uniprot:F1S8V5", "referenceType" : "ReferenceGeneProduct", "parents" : [ 10467111, 10467078, 10467076 ], "children" : [ ] }, { "dbId" : 10466819, "stId" : "R-SSC-202303", "displayName" : "p-6Y-CD247 dimer [plasma membrane]", "schemaClass" : "Complex", "speciesId" : 49633, "parents" : [ 10466821 ], "children" : [ 10466817 ] }, { "dbId" : 10475011, "stId" : "R-SSC-390925", "displayName" : "FYB1 [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49633, "diagramIds" : [ 113435 ], "identifier" : "K7GLT9", "standardIdentifier" : "uniprot:K7GLT9", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "FYB1" ], "parents" : [ 10478331 ], "children" : [ ] }, { "dbId" : 10466817, "stId" : "R-SSC-202166", "displayName" : "phospho-CD247 [plasma membrane]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49633, "identifier" : "K7GS60", "standardIdentifier" : "uniprot:K7GS60", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "CD247" ], "parents" : [ 10466819 ], "children" : [ ] }, { "dbId" : 10466879, "stId" : "R-SSC-202157", "displayName" : "Antigen-bearing MHC Class II : TCR complex:CD4:Lck [plasma membrane]", "schemaClass" : "Complex", "speciesId" : 49633, "diagramIds" : [ 113284 ], "parents" : [ ], "children" : [ 10465073, 10466725, 10466791, 10466877 ] }, { "dbId" : 10466877, "stId" : "R-SSC-167609", "displayName" : "LCK [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49633, "identifier" : "F1SV94", "standardIdentifier" : "uniprot:F1SV94", "referenceType" : "ReferenceGeneProduct", "parents" : [ 10466879 ], "children" : [ ] }, { "dbId" : 10466875, "stId" : "R-SSC-202154", "displayName" : "Antigen-bearing MHC Class II : TCR complex:CD4:p-Lck(Y505) [plasma membrane]", "schemaClass" : "Complex", "speciesId" : 49633, "diagramIds" : [ 113287 ], "parents" : [ ], "children" : [ 10465073, 10466725, 10466791, 10466873 ] }, { "dbId" : 10466873, "stId" : "R-SSC-202159", "displayName" : "phospho-p-Y505-LCK [plasma membrane]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49633, "identifier" : "F1SV94", "standardIdentifier" : "uniprot:F1SV94", "referenceType" : "ReferenceGeneProduct", "parents" : [ 10466875 ], "children" : [ ] }, { "dbId" : 10466868, "stId" : "R-SSC-202240", "displayName" : "PLCG1:p-5Y-LAT [plasma membrane]", "schemaClass" : "Complex", "speciesId" : 49633, "diagramIds" : [ 113331 ], "parents" : [ 10466948 ], "children" : [ 10466866, 10466857 ] }, { "dbId" : 29356, "stId" : "R-ALL-29356", "displayName" : "H2O [cytosol]", "schemaClass" : "SimpleEntity", "speciesId" : 0, "diagramIds" : [ 113362, 113348, 113290, 113450, 113455 ], "identifier" : "15377", "standardIdentifier" : "chebi:15377", "referenceType" : "ReferenceMolecule", "parents" : [ ], "children" : [ ] }, { "dbId" : 10466866, "stId" : "R-SSC-202364", "displayName" : "phospho-LAT [plasma membrane]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49633, "diagramIds" : [ 113312 ], "identifier" : "A0A480J3B5", "standardIdentifier" : "uniprot:A0A480J3B5", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "LAT" ], "parents" : [ 10466955, 10466868, 10466892 ], "children" : [ ] }, { "dbId" : 10466857, "stId" : "R-SSC-202320", "displayName" : "PLCG1 [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49633, "diagramIds" : [ 113328 ], "identifier" : "F1SDV6", "standardIdentifier" : "uniprot:F1SDV6", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "PLCG1" ], "parents" : [ 10466946, 10466868 ], "children" : [ ] }, { "dbId" : 29370, "stId" : "R-ALL-29370", "displayName" : "ADP [cytosol]", "schemaClass" : "SimpleEntity", "speciesId" : 0, "diagramIds" : [ 113313, 113377, 113382, 113286, 113323, 113418, 113388, 113423, 113295, 113360, 113299, 113398, 113432, 113336, 113304, 113308 ], "identifier" : "456216", "standardIdentifier" : "chebi:456216", "referenceType" : "ReferenceMolecule", "parents" : [ ], "children" : [ ] }, { "dbId" : 10466853, "stId" : "R-SSC-202283", "displayName" : "PI3K bound to TRAT [plasma membrane]", "schemaClass" : "Complex", "speciesId" : 49633, "diagramIds" : [ 113355 ], "parents" : [ ], "children" : [ 10466851, 10451791 ] }, { "dbId" : 29372, "stId" : "R-ALL-29372", "displayName" : "Pi [cytosol]", "schemaClass" : "SimpleEntity", "speciesId" : 0, "diagramIds" : [ 113456, 113364, 113291 ], "identifier" : "43474", "standardIdentifier" : "chebi:43474", "referenceType" : "ReferenceMolecule", "parents" : [ ], "children" : [ ] }, { "dbId" : 10466851, "stId" : "R-SSC-202201", "displayName" : "phospho-TRAT1 [plasma membrane]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49633, "diagramIds" : [ 113353 ], "identifier" : "A0A4X1SQN5", "standardIdentifier" : "uniprot:A0A4X1SQN5", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "TRAT1" ], "parents" : [ 10466853 ], "children" : [ ] }, { "dbId" : 10466911, "stId" : "R-SSC-202395", "displayName" : "phospho-p-Y90-PRKCQ [plasma membrane]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49633, "identifier" : "A0A4X1T8P0", "standardIdentifier" : "uniprot:A0A4X1T8P0", "referenceType" : "ReferenceGeneProduct", "parents" : [ 10466913 ], "children" : [ ] }, { "dbId" : 10533986, "stId" : "R-SSC-8852205", "displayName" : "PTPN22 [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49633, "diagramIds" : [ 113451 ], "identifier" : "A0A287BD80", "standardIdentifier" : "uniprot:A0A287BD80", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "PTPN22" ], "parents" : [ 10534624 ], "children" : [ ] }, { "dbId" : 10466905, "stId" : "R-SSC-202162", "displayName" : "p-Y113,128,145-SLP-76:GADS:LAT [plasma membrane]", "schemaClass" : "Complex", "speciesId" : 49633, "diagramIds" : [ 113322 ], "parents" : [ 10466957, 10466946, 10466965 ], "children" : [ 10466903, 10466892 ] }, { "dbId" : 10466903, "stId" : "R-SSC-202175", "displayName" : "phospho-LCP2 [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49633, "diagramIds" : [ 113434 ], "identifier" : "F1RRX4", "standardIdentifier" : "uniprot:F1RRX4", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "LCP2" ], "parents" : [ 10478331, 10478341, 10466905 ], "children" : [ ] }, { "dbId" : 10466898, "stId" : "R-SSC-202151", "displayName" : "SLP-76 bound to Gads:LAT [plasma membrane]", "schemaClass" : "Complex", "speciesId" : 49633, "diagramIds" : [ 113319 ], "parents" : [ ], "children" : [ 10466896, 10466892 ] }, { "dbId" : 10466896, "stId" : "R-SSC-202306", "displayName" : "LCP2 [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49633, "diagramIds" : [ 113318 ], "identifier" : "F1RRX4", "standardIdentifier" : "uniprot:F1RRX4", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "LCP2" ], "parents" : [ 10466898 ], "children" : [ ] }, { "dbId" : 10514545, "stId" : "R-SSC-5607697", "displayName" : "K48PolyUb-K21,22-p-S32,36-IkBA:NF-kB complex [cytosol]", "schemaClass" : "Complex", "speciesId" : 49633, "diagramIds" : [ 113444 ], "parents" : [ ], "children" : [ 10464103, 10489121 ] }, { "dbId" : 10466892, "stId" : "R-SSC-202177", "displayName" : "GADS:p-5Y-LAT [plasma membrane]", "schemaClass" : "Complex", "speciesId" : 49633, "diagramIds" : [ 113316 ], "parents" : [ 10466898, 10466905 ], "children" : [ 10466866, 10466890 ] }, { "dbId" : 10466890, "stId" : "R-SSC-202367", "displayName" : "FAM83F [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49633, "diagramIds" : [ 113315 ], "identifier" : "F1SRA1", "standardIdentifier" : "uniprot:F1SRA1", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "FAM83F" ], "parents" : [ 10466892 ], "children" : [ ] }, { "dbId" : 10466883, "stId" : "R-SSC-197931", "displayName" : "PTPRC [plasma membrane]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49633, "diagramIds" : [ 113288 ], "identifier" : "F1S5F1", "standardIdentifier" : "uniprot:F1S5F1", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "PTPRC" ], "parents" : [ ], "children" : [ ] }, { "dbId" : 10466942, "stId" : "R-SSC-202322", "displayName" : "LAT [plasma membrane]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49633, "diagramIds" : [ 113311 ], "identifier" : "A0A480J3B5", "standardIdentifier" : "uniprot:A0A480J3B5", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "LAT" ], "parents" : [ ], "children" : [ ] }, { "dbId" : 10474618, "stId" : "R-SSC-162629", "displayName" : "PAK1 [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49633, "identifier" : "A0A5G2QRJ6", "standardIdentifier" : "uniprot:A0A5G2QRJ6", "referenceType" : "ReferenceGeneProduct", "parents" : [ 10474630 ], "children" : [ ] }, { "dbId" : 10466935, "stId" : "R-SSC-197940", "displayName" : "INPP5D [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49633, "diagramIds" : [ 113365 ], "identifier" : "A0A287ABR0", "standardIdentifier" : "uniprot:A0A287ABR0", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "INPP5D" ], "parents" : [ ], "children" : [ ] }, { "dbId" : 10466927, "stId" : "R-SSC-202297", "displayName" : "Csk:p-PAG [plasma membrane]", "schemaClass" : "Complex", "speciesId" : 49633, "diagramIds" : [ 113282 ], "parents" : [ ], "children" : [ 10462113, 10466925 ] }, { "dbId" : 10466925, "stId" : "R-SSC-203776", "displayName" : "CSK [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49633, "diagramIds" : [ 113281 ], "identifier" : "F1SJ27", "standardIdentifier" : "uniprot:F1SJ27", "referenceType" : "ReferenceGeneProduct", "parents" : [ 10534624, 10466927 ], "children" : [ ] }, { "dbId" : 10466920, "stId" : "R-SSC-202442", "displayName" : "Active PKC theta bound to DAG [plasma membrane]", "schemaClass" : "Complex", "speciesId" : 49633, "diagramIds" : [ 113381 ], "parents" : [ ], "children" : [ 10466918, 112275 ] }, { "dbId" : 10466918, "stId" : "R-SSC-202152", "displayName" : "phospho-p-Y90,T538,S676,S695-PRKCQ [plasma membrane]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49633, "identifier" : "A0A4X1T8P0", "standardIdentifier" : "uniprot:A0A4X1T8P0", "referenceType" : "ReferenceGeneProduct", "parents" : [ 10466920 ], "children" : [ ] }, { "dbId" : 10459233, "stId" : "R-SSC-166366", "displayName" : "TRAF6 [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49633, "diagramIds" : [ 113408 ], "identifier" : "A7XUJ6", "standardIdentifier" : "uniprot:A7XUJ6", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "TRAF6" ], "parents" : [ 10467049 ], "children" : [ ] }, { "dbId" : 10466913, "stId" : "R-SSC-202300", "displayName" : "p-Y90-PKC-theta:DAG [plasma membrane]", "schemaClass" : "Complex", "speciesId" : 49633, "diagramIds" : [ 113376 ], "parents" : [ ], "children" : [ 112275, 10466911 ] }, { "dbId" : 10465693, "stId" : "R-SSC-199420", "displayName" : "PTEN [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49633, "diagramIds" : [ 113459 ], "identifier" : "F2Z5H1", "standardIdentifier" : "uniprot:F2Z5H1", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "PTEN" ], "parents" : [ ], "children" : [ ] }, { "dbId" : 10466714, "stId" : "R-SSC-202311", "displayName" : "PDK1:PIP2,PIP3 [plasma membrane]", "schemaClass" : "Complex", "speciesId" : 49633, "diagramIds" : [ 113369 ], "parents" : [ 10467008, 10467025, 10467030 ], "children" : [ 202277, 10454046 ] }, { "dbId" : 10466712, "stId" : "R-SSC-202210", "displayName" : "PDPK1 [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49633, "diagramIds" : [ 113368 ], "identifier" : "A0A287AST6", "standardIdentifier" : "uniprot:A0A287AST6", "referenceType" : "ReferenceGeneProduct", "parents" : [ ], "children" : [ ] }, { "dbId" : 10459538, "stId" : "R-SSC-450152", "displayName" : "K63polyUb [cytosol]", "schemaClass" : "Polymer", "speciesId" : 49633, "diagramIds" : [ 113426, 113412 ], "parents" : [ ], "children" : [ 10459536 ] }, { "dbId" : 10459536, "stId" : "R-SSC-450143", "displayName" : "K63-Ub [cytosol]", "schemaClass" : "DefinedSet", "speciesId" : 49633, "parents" : [ 10459538 ], "children" : [ 10459495, 10459498, 10459501 ] }, { "dbId" : 10464134, "stId" : "R-SSC-193938", "displayName" : "IkB(alpha):NF-kB complex [cytosol]", "schemaClass" : "Complex", "speciesId" : 49633, "diagramIds" : [ 113429 ], "parents" : [ ], "children" : [ 10464103, 10459352 ] }, { "dbId" : 10466751, "stId" : "R-SSC-197578", "displayName" : "HLA class II histocompatibility antigen, DQ [plasma membrane]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49633, "identifier" : "A0A5G2QCN4", "standardIdentifier" : "uniprot:A0A5G2QCN4", "referenceType" : "ReferenceGeneProduct", "parents" : [ 10466757 ], "children" : [ ] }, { "dbId" : 10466747, "stId" : "R-SSC-2130597", "displayName" : "HLA II alpha chain [plasma membrane]", "schemaClass" : "DefinedSet", "speciesId" : 49633, "parents" : [ 10466789 ], "children" : [ 10466745, 10466735 ] }, { "dbId" : 10466745, "stId" : "R-SSC-197588", "displayName" : "SLA-DRA1 [plasma membrane]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49633, "identifier" : "Q85ZW4", "standardIdentifier" : "uniprot:Q85ZW4", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "SLA-DRA1" ], "parents" : [ 10466747 ], "children" : [ ] }, { "dbId" : 10459568, "stId" : "R-SSC-202463", "displayName" : "UBE2N:UBE2V1 [cytosol]", "schemaClass" : "Complex", "speciesId" : 49633, "diagramIds" : [ 113425, 113411 ], "parents" : [ ], "children" : [ 10459562, 10459566 ] }, { "dbId" : 10466735, "stId" : "R-SSC-197576-3", "displayName" : "Homologues of HLA class II histocompatibility antigen, DQ [plasma membrane]", "schemaClass" : "DefinedSet", "speciesId" : 49633, "parents" : [ 10466747 ], "children" : [ 10466729, 10466733 ] }, { "dbId" : 10459566, "stId" : "R-SSC-205753", "displayName" : "UBE2V1 [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49633, "identifier" : "A0A4X1UIL1", "standardIdentifier" : "uniprot:A0A4X1UIL1", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "UBE2V1" ], "parents" : [ 10459568 ], "children" : [ ] }, { "dbId" : 10466733, "stId" : "R-SSC-197576-2", "displayName" : "SLA-DQA1 [plasma membrane]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49633, "identifier" : "Q7YQ94", "standardIdentifier" : "uniprot:Q7YQ94", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "SLA-DQA1" ], "parents" : [ 10466735 ], "children" : [ ] }, { "dbId" : 10459562, "stId" : "R-SSC-206072", "displayName" : "UBE2NL [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49633, "identifier" : "A0A5G2QZC6", "standardIdentifier" : "uniprot:A0A5G2QZC6", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "UBE2NL" ], "parents" : [ 10459568 ], "children" : [ ] }, { "dbId" : 10466729, "stId" : "R-SSC-197576", "displayName" : "HLA class II histocompatibility antigen, DQ [plasma membrane]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49633, "identifier" : "P15981", "standardIdentifier" : "uniprot:P15981", "referenceType" : "ReferenceGeneProduct", "parents" : [ 10466735 ], "children" : [ ] }, { "dbId" : 10466725, "stId" : "R-SSC-167542", "displayName" : "CD4 [plasma membrane]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49633, "identifier" : "I3L556", "standardIdentifier" : "uniprot:I3L556", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "CD4" ], "parents" : [ 10466875, 10466879, 10466793, 10466823 ], "children" : [ ] }, { "dbId" : 10462113, "stId" : "R-SSC-180494", "displayName" : "phospho-PAG1 [plasma membrane]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49633, "diagramIds" : [ 113280 ], "identifier" : "F1RXA1", "standardIdentifier" : "uniprot:F1RXA1", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "PAG1" ], "parents" : [ 10466927 ], "children" : [ ] }, { "dbId" : 10466721, "stId" : "R-SSC-202308", "displayName" : "phospho-p-Y394-LCK [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49633, "identifier" : "F1SV94", "standardIdentifier" : "uniprot:F1SV94", "referenceType" : "ReferenceGeneProduct", "parents" : [ 10466793, 10466823 ], "children" : [ ] }, { "dbId" : 10466783, "stId" : "R-SSC-882032-5", "displayName" : "LA-DRB-d [plasma membrane]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49633, "identifier" : "Q31072", "standardIdentifier" : "uniprot:Q31072", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "LA-DRB-d" ], "parents" : [ 10466785 ], "children" : [ ] }, { "dbId" : 10466779, "stId" : "R-SSC-882032-4", "displayName" : "HLA class II histocompatibility antigen, DR beta 4 chain [plasma membrane]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49633, "identifier" : "A0A8X9AEU9", "standardIdentifier" : "uniprot:A0A8X9AEU9", "referenceType" : "ReferenceGeneProduct", "parents" : [ 10466787, 10466785 ], "children" : [ ] }, { "dbId" : 10466775, "stId" : "R-SSC-882032-3", "displayName" : "HLA class II histocompatibility antigen, DR beta 4 chain [plasma membrane]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49633, "identifier" : "A0A8W4FBN9", "standardIdentifier" : "uniprot:A0A8W4FBN9", "referenceType" : "ReferenceGeneProduct", "parents" : [ 10466785 ], "children" : [ ] }, { "dbId" : 10466771, "stId" : "R-SSC-882032-2", "displayName" : "HLA class II histocompatibility antigen, DR beta 4 chain [plasma membrane]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49633, "identifier" : "A0A286ZUJ9", "standardIdentifier" : "uniprot:A0A286ZUJ9", "referenceType" : "ReferenceGeneProduct", "parents" : [ 10466785 ], "children" : [ ] }, { "dbId" : 2213228, "stId" : "R-ALL-2213228", "displayName" : "MHC class II epitopes [plasma membrane]", "schemaClass" : "OtherEntity", "speciesId" : 0, "parents" : [ 10466791 ], "children" : [ ] }, { "dbId" : 10466767, "stId" : "R-SSC-882032", "displayName" : "HLA class II histocompatibility antigen, DR beta 4 chain [plasma membrane]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49633, "identifier" : "A0A286ZKB7", "standardIdentifier" : "uniprot:A0A286ZKB7", "referenceType" : "ReferenceGeneProduct", "parents" : [ 10466785 ], "children" : [ ] }, { "dbId" : 10466763, "stId" : "R-SSC-197649-3", "displayName" : "Homologues of HLA class II histocompatibility antigen, DQ beta 2 chain [plasma membrane]", "schemaClass" : "DefinedSet", "speciesId" : 49633, "parents" : [ 10466787 ], "children" : [ 10466759, 10466761 ] }, { "dbId" : 10466761, "stId" : "R-SSC-197649-2", "displayName" : "HLA class II histocompatibility antigen, DQ beta 2 chain [plasma membrane]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49633, "identifier" : "A0A8W4F9V5", "standardIdentifier" : "uniprot:A0A8W4F9V5", "referenceType" : "ReferenceGeneProduct", "parents" : [ 10466763 ], "children" : [ ] }, { "dbId" : 10466759, "stId" : "R-SSC-197649", "displayName" : "HLA class II histocompatibility antigen, DQ beta 2 chain [plasma membrane]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49633, "identifier" : "A0A5G2QCN4", "standardIdentifier" : "uniprot:A0A5G2QCN4", "referenceType" : "ReferenceGeneProduct", "parents" : [ 10466763 ], "children" : [ ] }, { "dbId" : 114520, "stId" : "R-ALL-114520", "displayName" : "I(1,4,5)P3 [cytosol]", "schemaClass" : "SimpleEntity", "speciesId" : 0, "diagramIds" : [ 113350 ], "identifier" : "203600", "standardIdentifier" : "chebi:203600", "referenceType" : "ReferenceMolecule", "parents" : [ ], "children" : [ ] }, { "dbId" : 10466757, "stId" : "R-SSC-197578-3", "displayName" : "Homologues of HLA class II histocompatibility antigen, DQ [plasma membrane]", "schemaClass" : "DefinedSet", "speciesId" : 49633, "parents" : [ 10466787 ], "children" : [ 10466755, 10466751 ] }, { "dbId" : 10466755, "stId" : "R-SSC-197578-2", "displayName" : "HLA class II histocompatibility antigen, DQ [plasma membrane]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49633, "identifier" : "A0A8W4F9V5", "standardIdentifier" : "uniprot:A0A8W4F9V5", "referenceType" : "ReferenceGeneProduct", "parents" : [ 10466757 ], "children" : [ ] }, { "dbId" : 10466809, "stId" : "R-SSC-202167", "displayName" : "CD3 epsilon: CD3 gamma with phosphorylated ITAM [plasma membrane]", "schemaClass" : "Complex", "speciesId" : 49633, "parents" : [ 10466821 ], "children" : [ 10466807, 10466797 ] }, { "dbId" : 10466807, "stId" : "R-SSC-202362", "displayName" : "phospho-CD3G [plasma membrane]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49633, "identifier" : "Q5PXD3", "standardIdentifier" : "uniprot:Q5PXD3", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "CD3G" ], "parents" : [ 10466809 ], "children" : [ ] }, { "dbId" : 10466803, "stId" : "R-SSC-202336", "displayName" : "CD3 epsilon: CD3 delta with phosphorylated ITAMs [plasma membrane]", "schemaClass" : "Complex", "speciesId" : 49633, "parents" : [ 10466821 ], "children" : [ 10466801, 10466797 ] }, { "dbId" : 10466801, "stId" : "R-SSC-202329", "displayName" : "phospho-CD3D [plasma membrane]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49633, "identifier" : "Q764N2", "standardIdentifier" : "uniprot:Q764N2", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "CD3D" ], "parents" : [ 10466803 ], "children" : [ ] }, { "dbId" : 10466797, "stId" : "R-SSC-202228", "displayName" : "phospho-CD3E [plasma membrane]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49633, "identifier" : "A0A287B968", "standardIdentifier" : "uniprot:A0A287B968", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "CD3E" ], "parents" : [ 10466809, 10466803 ], "children" : [ ] }, { "dbId" : 10466793, "stId" : "R-SSC-202266", "displayName" : "Antigen-bearing MHC Class II :TCR complex:CD4: Lck phosphorylated at Tyr394 [plasma membrane]", "schemaClass" : "Complex", "speciesId" : 49633, "diagramIds" : [ 113378, 113294 ], "parents" : [ ], "children" : [ 10466721, 10465073, 10466725, 10466791 ] }, { "dbId" : 10466791, "stId" : "R-SSC-203463", "displayName" : "MHC Class II bearing antigen peptide [plasma membrane]", "schemaClass" : "Complex", "speciesId" : 49633, "parents" : [ 10466875, 10466879, 10466793, 10466823 ], "children" : [ 2213228, 10466789 ] }, { "dbId" : 10466789, "stId" : "R-SSC-2213189", "displayName" : "MHC class II alpha/beta dimer [plasma membrane]", "schemaClass" : "Complex", "speciesId" : 49633, "parents" : [ 10466791 ], "children" : [ 10466787, 10466747 ] }, { "dbId" : 10466787, "stId" : "R-SSC-2130476", "displayName" : "HLA II beta chain [plasma membrane]", "schemaClass" : "DefinedSet", "speciesId" : 49633, "parents" : [ 10466789 ], "children" : [ 10466785, 10466757, 10466779, 10466763 ] }, { "dbId" : 10466785, "stId" : "R-SSC-882032-6", "displayName" : "Homologues of HLA class II histocompatibility antigen, DR beta 4 chain [plasma membrane]", "schemaClass" : "DefinedSet", "speciesId" : 49633, "parents" : [ 10466787 ], "children" : [ 10466771, 10466775, 10466779, 10466783, 10466767 ] }, { "dbId" : 10465055, "stId" : "R-SSC-197906", "displayName" : "CD3E [plasma membrane]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49633, "identifier" : "A0A287B968", "standardIdentifier" : "uniprot:A0A287B968", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "CD3E" ], "parents" : [ 10465061, 10465067 ], "children" : [ ] }, { "dbId" : 10447647, "stId" : "R-SSC-68792", "displayName" : "PSMD12 [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49633, "identifier" : "A0A4X1SWC8", "standardIdentifier" : "uniprot:A0A4X1SWC8", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "PSMD12" ], "parents" : [ 10447655 ], "children" : [ ] }, { "dbId" : 10489121, "stId" : "R-SSC-1168581", "displayName" : "phospho-NFKBIA [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49633, "identifier" : "Q08353", "standardIdentifier" : "uniprot:Q08353", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "NFKBIA" ], "parents" : [ 10514545 ], "children" : [ ] }, { "dbId" : 10447645, "stId" : "R-SSC-68790", "displayName" : "PSMD11 [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49633, "identifier" : "F1RKW8", "standardIdentifier" : "uniprot:F1RKW8", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "PSMD11" ], "parents" : [ 10447657 ], "children" : [ ] }, { "dbId" : 10467100, "stId" : "R-SSC-202504", "displayName" : "TAB2/TAK1 complex [cytosol]", "schemaClass" : "Complex", "speciesId" : 49633, "diagramIds" : [ 113415 ], "parents" : [ ], "children" : [ 10467098, 10467082 ] }, { "dbId" : 10465051, "stId" : "R-SSC-198183", "displayName" : "T-cell receptor [plasma membrane]", "schemaClass" : "Complex", "speciesId" : 49633, "parents" : [ 10465073, 10466821 ], "children" : [ 10465029, 10465049 ] }, { "dbId" : 10447643, "stId" : "R-SSC-9908170", "displayName" : "19S RP base [cytosol]", "schemaClass" : "Complex", "speciesId" : 49633, "parents" : [ 10447673 ], "children" : [ 10447621, 10447623, 10447641, 10447625, 10447631 ] }, { "dbId" : 10467098, "stId" : "R-SSC-168163", "displayName" : "phospho-p-MAP3K7 [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49633, "identifier" : "B0LXP5", "standardIdentifier" : "uniprot:B0LXP5", "referenceType" : "ReferenceGeneProduct", "parents" : [ 10467100 ], "children" : [ ] }, { "dbId" : 10465049, "stId" : "R-SSC-198177", "displayName" : "TCR chain beta [plasma membrane]", "schemaClass" : "DefinedSet", "speciesId" : 49633, "parents" : [ 10465051 ], "children" : [ 10465043, 10465047, 10465033 ] }, { "dbId" : 10447641, "stId" : "R-SSC-9908171", "displayName" : "PSMC2:PSMC1:PSMD2 [cytosol]", "schemaClass" : "Complex", "speciesId" : 49633, "parents" : [ 10447643 ], "children" : [ 10447637, 10447639 ] }, { "dbId" : 10465047, "stId" : "R-SSC-198181", "displayName" : "TRBV12-3 [plasma membrane]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49633, "identifier" : "A0A8W4FP49", "standardIdentifier" : "uniprot:A0A8W4FP49", "referenceType" : "ReferenceGeneProduct", "parents" : [ 10465049 ], "children" : [ ] }, { "dbId" : 10447639, "stId" : "R-SSC-68796", "displayName" : "PSMD2 [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49633, "identifier" : "A0A480JRT9", "standardIdentifier" : "uniprot:A0A480JRT9", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "PSMD2" ], "parents" : [ 10447641 ], "children" : [ ] }, { "dbId" : 10447637, "stId" : "R-SSC-9907947", "displayName" : "PSMC2:PSMC1 [cytosol]", "schemaClass" : "Complex", "speciesId" : 49633, "parents" : [ 10447641 ], "children" : [ 10447633, 10447635 ] }, { "dbId" : 10467092, "stId" : "R-SSC-202507", "displayName" : "TAK1/TAB2 complex bound to TRAF6/CBM complex [plasma membrane]", "schemaClass" : "Complex", "speciesId" : 49633, "diagramIds" : [ 113417 ], "parents" : [ ], "children" : [ 10467090, 10467054 ] }, { "dbId" : 10465043, "stId" : "R-SSC-198187-3", "displayName" : "Homologues of TCRB [plasma membrane]", "schemaClass" : "DefinedSet", "speciesId" : 49633, "parents" : [ 10465049 ], "children" : [ 10465041, 10465037 ] }, { "dbId" : 10447635, "stId" : "R-SSC-68771", "displayName" : "PSMC2 [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49633, "identifier" : "A0A4X1VCL1", "standardIdentifier" : "uniprot:A0A4X1VCL1", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "PSMC2" ], "parents" : [ 10447637 ], "children" : [ ] }, { "dbId" : 10467090, "stId" : "R-SSC-202516", "displayName" : "phosphorylated TAK1 bound to TAB2 [cytosol]", "schemaClass" : "Complex", "speciesId" : 49633, "parents" : [ 10467092 ], "children" : [ 10467088, 10467082 ] }, { "dbId" : 10465041, "stId" : "R-SSC-198187-2", "displayName" : "TCRB [plasma membrane]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49633, "identifier" : "A0A8W4FNK4", "standardIdentifier" : "uniprot:A0A8W4FNK4", "referenceType" : "ReferenceGeneProduct", "parents" : [ 10465043 ], "children" : [ ] }, { "dbId" : 10447633, "stId" : "R-SSC-68768", "displayName" : "PSMC1 [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49633, "identifier" : "F2Z5J1", "standardIdentifier" : "uniprot:F2Z5J1", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "PSMC1" ], "parents" : [ 10447637 ], "children" : [ ] }, { "dbId" : 10467088, "stId" : "R-SSC-202527", "displayName" : "phospho-p-T184,T187-MAP3K7 [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49633, "identifier" : "B0LXP5", "standardIdentifier" : "uniprot:B0LXP5", "referenceType" : "ReferenceGeneProduct", "parents" : [ 10467090 ], "children" : [ ] }, { "dbId" : 10447631, "stId" : "R-SSC-9907949", "displayName" : "PSMC4:PSMC5 [cytosol]", "schemaClass" : "Complex", "speciesId" : 49633, "parents" : [ 10447643 ], "children" : [ 10447627, 10447629 ] }, { "dbId" : 10465037, "stId" : "R-SSC-198187", "displayName" : "TCRB [plasma membrane]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49633, "identifier" : "A0A287AT33", "standardIdentifier" : "uniprot:A0A287AT33", "referenceType" : "ReferenceGeneProduct", "parents" : [ 10465043 ], "children" : [ ] }, { "dbId" : 10464013, "stId" : "R-SSC-168402", "displayName" : "RIPK2 [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49633, "diagramIds" : [ 113400 ], "identifier" : "K7GL70", "standardIdentifier" : "uniprot:K7GL70", "referenceType" : "ReferenceGeneProduct", "parents" : [ ], "children" : [ ] }, { "dbId" : 10447629, "stId" : "R-SSC-68780", "displayName" : "Ghost homologue of PSMC5 [cytosol]", "schemaClass" : "GenomeEncodedEntity", "speciesId" : 49633, "parents" : [ 10447631 ], "children" : [ ] }, { "dbId" : 10447627, "stId" : "R-SSC-68777", "displayName" : "PSMC4 [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49633, "identifier" : "A0A4X1SRU3", "standardIdentifier" : "uniprot:A0A4X1SRU3", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "PSMC4" ], "parents" : [ 10447631 ], "children" : [ ] }, { "dbId" : 10467082, "stId" : "R-SSC-168116", "displayName" : "TAB2 [plasma membrane]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49633, "identifier" : "F1S7S1", "standardIdentifier" : "uniprot:F1S7S1", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "TAB2" ], "parents" : [ 10467100, 10467090 ], "children" : [ ] }, { "dbId" : 10465033, "stId" : "R-SSC-198188", "displayName" : "TRBC1 [plasma membrane]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49633, "identifier" : "A0A287BQ31", "standardIdentifier" : "uniprot:A0A287BQ31", "referenceType" : "ReferenceGeneProduct", "parents" : [ 10465049 ], "children" : [ ] }, { "dbId" : 10447625, "stId" : "R-SSC-68786", "displayName" : "PSMD1 [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49633, "identifier" : "F1SMW9", "standardIdentifier" : "uniprot:F1SMW9", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "PSMD1" ], "parents" : [ 10447643 ], "children" : [ ] }, { "dbId" : 10478343, "stId" : "R-SSC-430189", "displayName" : "p-SLP-76:NCK:PAK [cytosol]", "schemaClass" : "Complex", "speciesId" : 49633, "diagramIds" : [ 113442 ], "parents" : [ ], "children" : [ 10478341, 10474630 ] }, { "dbId" : 10447623, "stId" : "R-SSC-5665939", "displayName" : "ADRM1 [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49633, "identifier" : "A0A8W4F8D7", "standardIdentifier" : "uniprot:A0A8W4F8D7", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "ADRM1" ], "parents" : [ 10447643 ], "children" : [ ] }, { "dbId" : 10467078, "stId" : "R-SSC-202513", "displayName" : "CHUK:p-S177,S181-IKBKB:IKBKG [cytosol]", "schemaClass" : "Complex", "speciesId" : 49633, "diagramIds" : [ 113422 ], "parents" : [ ], "children" : [ 10464773, 10459386, 10459374 ] }, { "dbId" : 10465029, "stId" : "R-SSC-198184", "displayName" : "TCR chain alpha [plasma membrane]", "schemaClass" : "DefinedSet", "speciesId" : 49633, "parents" : [ 10465051 ], "children" : [ 10465027, 10465023 ] }, { "dbId" : 10478341, "stId" : "R-SSC-430188", "displayName" : "p-SLP-76:NCK1 [cytosol]", "schemaClass" : "Complex", "speciesId" : 49633, "diagramIds" : [ 113439 ], "parents" : [ 10478343 ], "children" : [ 10466903, 10471070 ] }, { "dbId" : 10447621, "stId" : "R-SSC-9907950", "displayName" : "PSMC3:PSMC6 [cytosol]", "schemaClass" : "Complex", "speciesId" : 49633, "parents" : [ 10447643 ], "children" : [ 10447617, 10447619 ] }, { "dbId" : 10467076, "stId" : "R-SSC-168113", "displayName" : "CHUK:IKBKB:IKBKG [cytosol]", "schemaClass" : "Complex", "speciesId" : 49633, "diagramIds" : [ 113420 ], "parents" : [ ], "children" : [ 10463957, 10464773, 10459374 ] }, { "dbId" : 10465027, "stId" : "R-SSC-9608264", "displayName" : "TRAV19 [plasma membrane]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49633, "identifier" : "A0A4X1V2B8", "standardIdentifier" : "uniprot:A0A4X1V2B8", "referenceType" : "ReferenceGeneProduct", "parents" : [ 10465029 ], "children" : [ ] }, { "dbId" : 10447619, "stId" : "R-SSC-68783", "displayName" : "PSMC6 [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49633, "identifier" : "A0A287BG14", "standardIdentifier" : "uniprot:A0A287BG14", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "PSMC6" ], "parents" : [ 10447621 ], "children" : [ ] }, { "dbId" : 10447617, "stId" : "R-SSC-68774", "displayName" : "PSMC3 [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49633, "identifier" : "A0A8W4FR49", "standardIdentifier" : "uniprot:A0A8W4FR49", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "PSMC3" ], "parents" : [ 10447621 ], "children" : [ ] }, { "dbId" : 10447679, "stId" : "R-SSC-68747", "displayName" : "PSMB3 [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49633, "identifier" : "A0A286ZN52", "standardIdentifier" : "uniprot:A0A286ZN52", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "PSMB3" ], "parents" : [ 10447689 ], "children" : [ ] }, { "dbId" : 10451773, "stId" : "R-SSC-74789", "displayName" : "PIK3R1 [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49633, "identifier" : "F1SKR9", "standardIdentifier" : "uniprot:F1SKR9", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "PIK3R1" ], "parents" : [ 10451779 ], "children" : [ ] }, { "dbId" : 10447677, "stId" : "R-SSC-68744", "displayName" : "PSMB2 [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49633, "identifier" : "A0A4X1VZE2", "standardIdentifier" : "uniprot:A0A4X1VZE2", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "PSMB2" ], "parents" : [ 10447689 ], "children" : [ ] }, { "dbId" : 10447675, "stId" : "R-SSC-68738", "displayName" : "PSMB1 [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49633, "identifier" : "A0A287BPP9", "standardIdentifier" : "uniprot:A0A287BPP9", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "PSMB1" ], "parents" : [ 10447689 ], "children" : [ ] }, { "dbId" : 10447673, "stId" : "R-SSC-9908177", "displayName" : "19S regulatory particle [cytosol]", "schemaClass" : "Complex", "speciesId" : 49633, "parents" : [ 10447709 ], "children" : [ 10447671, 10447643 ] }, { "dbId" : 10447671, "stId" : "R-SSC-9908021", "displayName" : "19S RP lid [cytosol]", "schemaClass" : "Complex", "speciesId" : 49633, "parents" : [ 10447673 ], "children" : [ 10447667, 10447669 ] }, { "dbId" : 10447669, "stId" : "R-SSC-68808", "displayName" : "PSMD8 [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49633, "identifier" : "A0A287B5Q7", "standardIdentifier" : "uniprot:A0A287B5Q7", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "PSMD8" ], "parents" : [ 10447671 ], "children" : [ ] }, { "dbId" : 10447667, "stId" : "R-SSC-9908012", "displayName" : "19S RP lid particle 2 [cytosol]", "schemaClass" : "Complex", "speciesId" : 49633, "parents" : [ 10447671 ], "children" : [ 10447665, 10447657 ] }, { "dbId" : 10556175, "stId" : "R-SSC-1257604", "displayName" : "PIP3 activates AKT signaling", "schemaClass" : "Pathway", "speciesId" : 49633, "diagramIds" : [ 113464 ] }, { "dbId" : 10465073, "stId" : "R-SSC-198901", "displayName" : "T-cell receptor complex [plasma membrane]", "schemaClass" : "Complex", "speciesId" : 49633, "parents" : [ 10466875, 10466879, 10466793 ], "children" : [ 10465061, 10465067, 10465051, 10465071 ] }, { "dbId" : 10447665, "stId" : "R-SSC-9908004", "displayName" : "19S RP lid particle 3 [cytosol]", "schemaClass" : "Complex", "speciesId" : 49633, "parents" : [ 10447667 ], "children" : [ 10447659, 10447661, 10447663 ] }, { "dbId" : 10465071, "stId" : "R-SSC-198166", "displayName" : "CD247 [plasma membrane]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49633, "identifier" : "K7GS60", "standardIdentifier" : "uniprot:K7GS60", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "CD247" ], "parents" : [ 10465073 ], "children" : [ ] }, { "dbId" : 10447663, "stId" : "R-SSC-8866674", "displayName" : "Ghost homologue of SEM1 [cytosol]", "schemaClass" : "GenomeEncodedEntity", "speciesId" : 49633, "parents" : [ 10447665 ], "children" : [ ] }, { "dbId" : 10447661, "stId" : "R-SSC-68804", "displayName" : "PSMD6 [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49633, "identifier" : "F1SGF1", "standardIdentifier" : "uniprot:F1SGF1", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "PSMD6" ], "parents" : [ 10447665 ], "children" : [ ] }, { "dbId" : 10467116, "stId" : "R-SSC-5607671", "displayName" : "p-S32,36-IkB-alpha:NF-kB complex [cytosol]", "schemaClass" : "Complex", "speciesId" : 49633, "diagramIds" : [ 113431 ], "parents" : [ ], "children" : [ 10459364, 10464103 ] }, { "dbId" : 10465067, "stId" : "R-SSC-198902", "displayName" : "CD3 epsilon gamma [plasma membrane]", "schemaClass" : "Complex", "speciesId" : 49633, "parents" : [ 10465073 ], "children" : [ 10465065, 10465055 ] }, { "dbId" : 10447659, "stId" : "R-SSC-68798", "displayName" : "PSMD3 [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49633, "identifier" : "F1RXA7", "standardIdentifier" : "uniprot:F1RXA7", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "PSMD3" ], "parents" : [ 10447665 ], "children" : [ ] }, { "dbId" : 10465065, "stId" : "R-SSC-197917", "displayName" : "CD3G [plasma membrane]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49633, "identifier" : "Q5PXD3", "standardIdentifier" : "uniprot:Q5PXD3", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "CD3G" ], "parents" : [ 10465067 ], "children" : [ ] }, { "dbId" : 10447657, "stId" : "R-SSC-9907993", "displayName" : "19S RP Lid Module 1 [cytosol]", "schemaClass" : "Complex", "speciesId" : 49633, "parents" : [ 10447667 ], "children" : [ 10447655, 10447645 ] }, { "dbId" : 10459433, "stId" : "R-SSC-177676", "displayName" : "RELA [nucleoplasm]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49633, "identifier" : "F6PVF4", "standardIdentifier" : "uniprot:F6PVF4", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "RELA" ], "parents" : [ 10464105 ], "children" : [ ] }, { "dbId" : 10467111, "stId" : "R-SSC-202562", "displayName" : "CHUK:p-S177,S181-IKBKB:pUb-IKBKG [cytosol]", "schemaClass" : "Complex", "speciesId" : 49633, "diagramIds" : [ 113427 ], "parents" : [ ], "children" : [ 10467109, 10464773, 10459386 ] }, { "dbId" : 10447655, "stId" : "R-SSC-9907994", "displayName" : "PSMD7:PSMD12:PSMD13:PSMD14 [cytosol]", "schemaClass" : "Complex", "speciesId" : 49633, "parents" : [ 10447657 ], "children" : [ 10447649, 10447651, 10447653, 10447647 ] }, { "dbId" : 113592, "stId" : "R-ALL-113592", "displayName" : "ATP [cytosol]", "schemaClass" : "SimpleEntity", "speciesId" : 0, "diagramIds" : [ 113285, 113380, 113321, 113416, 113387, 113357, 113293, 113421, 113297, 113397, 113302, 113334, 113430, 113306, 113375, 113310 ], "identifier" : "30616", "standardIdentifier" : "chebi:30616", "referenceType" : "ReferenceMolecule", "parents" : [ ], "children" : [ ] }, { "dbId" : 10465061, "stId" : "R-SSC-198900", "displayName" : "CD3 epsilon delta [plasma membrane]", "schemaClass" : "Complex", "speciesId" : 49633, "parents" : [ 10465073 ], "children" : [ 10465059, 10465055 ] }, { "dbId" : 10467109, "stId" : "R-SSC-202530", "displayName" : "K63polyUb-IKBKG [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49633, "identifier" : "A9QT41", "standardIdentifier" : "uniprot:A9QT41", "referenceType" : "ReferenceGeneProduct", "parents" : [ 10467111 ], "children" : [ ] }, { "dbId" : 10447653, "stId" : "R-SSC-68794", "displayName" : "PSMD13 [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49633, "identifier" : "A0A4X1VZI2", "standardIdentifier" : "uniprot:A0A4X1VZI2", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "PSMD13" ], "parents" : [ 10447655 ], "children" : [ ] }, { "dbId" : 10465059, "stId" : "R-SSC-198171", "displayName" : "CD3D [plasma membrane]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49633, "identifier" : "Q764N2", "standardIdentifier" : "uniprot:Q764N2", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "CD3D" ], "parents" : [ 10465061 ], "children" : [ ] }, { "dbId" : 10447651, "stId" : "R-SSC-68806", "displayName" : "PSMD7 [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49633, "identifier" : "A0A287AEH0", "standardIdentifier" : "uniprot:A0A287AEH0", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "PSMD7" ], "parents" : [ 10447655 ], "children" : [ ] }, { "dbId" : 10459427, "stId" : "R-SSC-177655", "displayName" : "NFKB1 [nucleoplasm]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49633, "identifier" : "A0A287AVR3", "standardIdentifier" : "uniprot:A0A287AVR3", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "NFKB1" ], "parents" : [ 10464105 ], "children" : [ ] }, { "dbId" : 10447649, "stId" : "R-SSC-68722", "displayName" : "PSMD14 [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49633, "identifier" : "F1RPQ3", "standardIdentifier" : "uniprot:F1RPQ3", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "PSMD14" ], "parents" : [ 10447655 ], "children" : [ ] }, { "dbId" : 10447709, "stId" : "R-SSC-68819", "displayName" : "26S proteasome [cytosol]", "schemaClass" : "Complex", "speciesId" : 49633, "diagramIds" : [ 113446 ], "parents" : [ ], "children" : [ 10447673, 10447707 ] }, { "dbId" : 10447707, "stId" : "R-SSC-9907918", "displayName" : "20S core particle [cytosol]", "schemaClass" : "Complex", "speciesId" : 49633, "parents" : [ 10447709 ], "children" : [ 10447705, 10447689 ] }, { "dbId" : 10447705, "stId" : "R-SSC-9907911", "displayName" : "20S CP outer ring [cytosol]", "schemaClass" : "Complex", "speciesId" : 49633, "parents" : [ 10447707 ], "children" : [ 10447697, 10447699, 10447701, 10447703, 10447691, 10447693, 10447695 ] }, { "dbId" : 10447703, "stId" : "R-SSC-68736", "displayName" : "PSMA7 [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49633, "identifier" : "A0A287AT18", "standardIdentifier" : "uniprot:A0A287AT18", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "PSMA7" ], "parents" : [ 10447705 ], "children" : [ ] }, { "dbId" : 10447701, "stId" : "R-SSC-68734", "displayName" : "PSMA6 [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49633, "identifier" : "F2Z5N0", "standardIdentifier" : "uniprot:F2Z5N0", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "PSMA6" ], "parents" : [ 10447705 ], "children" : [ ] }, { "dbId" : 10447699, "stId" : "R-SSC-68732", "displayName" : "Ghost homologue of PSMA5 [cytosol]", "schemaClass" : "GenomeEncodedEntity", "speciesId" : 49633, "parents" : [ 10447705 ], "children" : [ ] }, { "dbId" : 10447697, "stId" : "R-SSC-68730", "displayName" : "Ghost homologue of PSMA4 [cytosol]", "schemaClass" : "GenomeEncodedEntity", "speciesId" : 49633, "parents" : [ 10447705 ], "children" : [ ] }, { "dbId" : 10451791, "stId" : "R-SSC-74693", "displayName" : "PI3K [cytosol]", "schemaClass" : "Complex", "speciesId" : 49633, "diagramIds" : [ 113354 ], "parents" : [ 10466853 ], "children" : [ 10451779, 10451789 ] }, { "dbId" : 10447695, "stId" : "R-SSC-68728", "displayName" : "PSMA3 [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49633, "identifier" : "A0A8D0UCW9", "standardIdentifier" : "uniprot:A0A8D0UCW9", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "PSMA3" ], "parents" : [ 10447705 ], "children" : [ ] }, { "dbId" : 10451789, "stId" : "R-SSC-74689", "displayName" : "PI3K-catalytic subunit [cytosol]", "schemaClass" : "DefinedSet", "speciesId" : 49633, "parents" : [ 10451791 ], "children" : [ 10451783, 10451787 ] }, { "dbId" : 10447693, "stId" : "R-SSC-68726", "displayName" : "Ghost homologue of PSMA2 [cytosol]", "schemaClass" : "GenomeEncodedEntity", "speciesId" : 49633, "parents" : [ 10447705 ], "children" : [ ] }, { "dbId" : 10451787, "stId" : "R-SSC-74788", "displayName" : "PIK3CB [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49633, "identifier" : "A0A8X9AEI7", "standardIdentifier" : "uniprot:A0A8X9AEI7", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "PIK3CB" ], "parents" : [ 10451789 ], "children" : [ ] }, { "dbId" : 10447691, "stId" : "R-SSC-68724", "displayName" : "Ghost homologue of PSMA1 [cytosol]", "schemaClass" : "GenomeEncodedEntity", "speciesId" : 49633, "parents" : [ 10447705 ], "children" : [ ] }, { "dbId" : 10447689, "stId" : "R-SSC-9907905", "displayName" : "20S CP inner ring [cytosol]", "schemaClass" : "Complex", "speciesId" : 49633, "parents" : [ 10447707 ], "children" : [ 10447681, 10447683, 10447685, 10447687, 10447675, 10447677, 10447679 ] }, { "dbId" : 10451783, "stId" : "R-SSC-74787", "displayName" : "PIK3CA [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49633, "identifier" : "A0A5K1UB41", "standardIdentifier" : "uniprot:A0A5K1UB41", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "PIK3CA" ], "parents" : [ 10451789 ], "children" : [ ] }, { "dbId" : 10447687, "stId" : "R-SSC-68759", "displayName" : "PSMB7 [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49633, "identifier" : "A1XQU1", "standardIdentifier" : "uniprot:A1XQU1", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "PSMB7" ], "parents" : [ 10447689 ], "children" : [ ] }, { "dbId" : 10447685, "stId" : "R-SSC-68756", "displayName" : "Ghost homologue of PSMB6 [cytosol]", "schemaClass" : "GenomeEncodedEntity", "speciesId" : 49633, "parents" : [ 10447689 ], "children" : [ ] }, { "dbId" : 10451779, "stId" : "R-SSC-74688", "displayName" : "PI3K-regulatory subunit [cytosol]", "schemaClass" : "DefinedSet", "speciesId" : 49633, "parents" : [ 10451791 ], "children" : [ 10451777, 10451773 ] }, { "dbId" : 10447683, "stId" : "R-SSC-68753", "displayName" : "PSMB5 [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49633, "identifier" : "A0A286ZS34", "standardIdentifier" : "uniprot:A0A286ZS34", "referenceType" : "ReferenceGeneProduct", "parents" : [ 10447689 ], "children" : [ ] }, { "dbId" : 10451777, "stId" : "R-SSC-74791", "displayName" : "PIK3R2 [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49633, "identifier" : "F1S916", "standardIdentifier" : "uniprot:F1S916", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "PIK3R2" ], "parents" : [ 10451779 ], "children" : [ ] }, { "dbId" : 10447681, "stId" : "R-SSC-68750", "displayName" : "Ghost homologue of PSMB4 [cytosol]", "schemaClass" : "GenomeEncodedEntity", "speciesId" : 49633, "parents" : [ 10447689 ], "children" : [ ] }, { "dbId" : 10459501, "stId" : "R-SSC-939224", "displayName" : "UBC [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49633, "identifier" : "P0CG68", "standardIdentifier" : "uniprot:P0CG68", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "UBC" ], "parents" : [ 10459536 ], "children" : [ ] }, { "dbId" : 10459498, "stId" : "R-SSC-939169", "displayName" : "UBA52 [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49633, "identifier" : "P63053", "standardIdentifier" : "uniprot:P63053", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "UBA52" ], "parents" : [ 10459536 ], "children" : [ ] }, { "dbId" : 10464105, "stId" : "R-SSC-194047", "displayName" : "NFKB1(1-433):RELA [nucleoplasm]", "schemaClass" : "Complex", "speciesId" : 49633, "diagramIds" : [ 113448 ], "parents" : [ ], "children" : [ 10459427, 10459433 ] }, { "dbId" : 10459495, "stId" : "R-SSC-939248", "displayName" : "RPS27A [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49633, "identifier" : "A0A287AZA7", "standardIdentifier" : "uniprot:A0A287AZA7", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "RPS27A" ], "parents" : [ 10459536 ], "children" : [ ] }, { "dbId" : 10464103, "stId" : "R-SSC-194043", "displayName" : "NFKB1(1-433):RELA [cytosol]", "schemaClass" : "Complex", "speciesId" : 49633, "diagramIds" : [ 113445 ], "parents" : [ 10464134, 10467116, 10514545 ], "children" : [ 10459336, 10459340 ] } ], "edges" : [ { "dbId" : 10467103, "stId" : "R-SSC-202510", "displayName" : "Activation of TAK1-TAB2 complex", "schemaClass" : "Reaction", "speciesId" : 0, "preceding" : [ 10467057 ], "following" : [ 10467095 ], "inputs" : [ 113592, 10467100, 10467054 ], "outputs" : [ 10467092, 29370 ], "catalysts" : [ 10467100 ], "efs" : [ ], "diagramIds" : [ 113414 ], "entityFunctionalStatus" : [ ] }, { "dbId" : 10466974, "stId" : "R-SSC-202248", "displayName" : "Phosphorylation of PLC-gamma1", "schemaClass" : "Reaction", "speciesId" : 0, "preceding" : [ 10466870, 10467002, 10466990 ], "following" : [ 10466997, 10469553, 10469555 ], "inputs" : [ 10466948, 113592 ], "outputs" : [ 29370, 10466959 ], "catalysts" : [ 10466967 ], "efs" : [ ], "inhibitors" : [ 10466972 ], "diagramIds" : [ 113332 ], "entityFunctionalStatus" : [ ] }, { "dbId" : 10534626, "stId" : "R-SSC-8855375", "displayName" : "PTPN22 dissociates from CSK", "schemaClass" : "Reaction", "speciesId" : 0, "following" : [ 10534628, 10533989 ], "inputs" : [ 10534624 ], "outputs" : [ 10533986, 10466925 ], "efs" : [ ], "diagramIds" : [ 113452 ], "entityFunctionalStatus" : [ ] }, { "dbId" : 10466844, "stId" : "R-SSC-202174", "displayName" : "Activation of ZAP-70", "schemaClass" : "Reaction", "speciesId" : 0, "preceding" : [ 10466837 ], "following" : [ 10466944 ], "inputs" : [ 10466834, 113592 ], "outputs" : [ 29370, 10466841 ], "catalysts" : [ 10466834 ], "efs" : [ ], "diagramIds" : [ 113305 ], "entityFunctionalStatus" : [ ] }, { "dbId" : 10466908, "stId" : "R-SSC-202216", "displayName" : "Phosphorylation of SLP-76", "schemaClass" : "Reaction", "speciesId" : 0, "preceding" : [ 10466940 ], "following" : [ 10478333, 10466990, 10467002 ], "inputs" : [ 10466898, 113592 ], "outputs" : [ 29370, 10466905 ], "catalysts" : [ 10466841 ], "efs" : [ ], "diagramIds" : [ 113320 ], "entityFunctionalStatus" : [ ] }, { "dbId" : 10466716, "stId" : "R-SSC-202164", "displayName" : "Translocation of PDK1 to Plasma membrane", "schemaClass" : "Reaction", "speciesId" : 0, "preceding" : [ 10467000, 10466938 ], "following" : [ 10466988 ], "inputs" : [ 10466712, 202277 ], "outputs" : [ 10466714 ], "efs" : [ ], "diagramIds" : [ 113366 ], "entityFunctionalStatus" : [ ] }, { "dbId" : 10534628, "stId" : "R-SSC-8855381", "displayName" : "PTPN22 dephosphorylates ZAP70", "schemaClass" : "Reaction", "speciesId" : 0, "preceding" : [ 10466837, 10534626 ], "inputs" : [ 10466834, 29356 ], "outputs" : [ 29372, 10466830 ], "catalysts" : [ 10533986 ], "efs" : [ ], "diagramIds" : [ 113454 ], "entityFunctionalStatus" : [ ] }, { "dbId" : 10533989, "stId" : "R-SSC-8852200", "displayName" : "Inactivation of LCK by PTPN22", "schemaClass" : "Reaction", "speciesId" : 0, "preceding" : [ 10466978, 10534626 ], "inputs" : [ 29356, 10466793 ], "outputs" : [ 29372, 10466879 ], "catalysts" : [ 10533986 ], "efs" : [ ], "diagramIds" : [ 113449 ], "entityFunctionalStatus" : [ ] }, { "dbId" : 10467032, "stId" : "R-SSC-202443", "displayName" : "Oligomerization of CARMA1", "schemaClass" : "Reaction", "speciesId" : 0, "preceding" : [ 10467028 ], "following" : [ 10467068 ], "inputs" : [ 10467025, 10467023 ], "outputs" : [ 10467030 ], "efs" : [ ], "diagramIds" : [ 113390 ], "entityFunctionalStatus" : [ ] }, { "dbId" : 10467095, "stId" : "R-SSC-202500", "displayName" : "Activation of IKK complex", "schemaClass" : "Reaction", "speciesId" : 0, "preceding" : [ 10467103 ], "following" : [ 10467114 ], "inputs" : [ 10467076, 113592 ], "outputs" : [ 29370, 10467078 ], "catalysts" : [ 10467092 ], "efs" : [ ], "diagramIds" : [ 113419 ], "entityFunctionalStatus" : [ ] }, { "dbId" : 10466837, "stId" : "R-SSC-202168", "displayName" : "Phosphorylation of ZAP-70 by Lck", "schemaClass" : "Reaction", "speciesId" : 0, "following" : [ 10534628, 10466844 ], "inputs" : [ 113592, 10466830 ], "outputs" : [ 10466834, 29370 ], "catalysts" : [ 10466793 ], "efs" : [ ], "diagramIds" : [ 113300 ], "entityFunctionalStatus" : [ ] }, { "dbId" : 10467028, "stId" : "R-SSC-202437", "displayName" : "Phosphorylation of CARMA1", "schemaClass" : "Reaction", "speciesId" : 0, "preceding" : [ 10467010 ], "following" : [ 10467032 ], "inputs" : [ 10467008, 113592 ], "outputs" : [ 10467025, 29370 ], "catalysts" : [ 10466920 ], "efs" : [ ], "diagramIds" : [ 113386 ], "entityFunctionalStatus" : [ ] }, { "dbId" : 10467020, "stId" : "R-SSC-202407", "displayName" : "PLC-gamma1 hydrolyses PIP2", "schemaClass" : "Reaction", "speciesId" : 0, "preceding" : [ 10466997 ], "following" : [ 10466855 ], "inputs" : [ 29356, 179856 ], "outputs" : [ 114520, 112275 ], "catalysts" : [ 10467017 ], "efs" : [ ], "diagramIds" : [ 113347 ], "entityFunctionalStatus" : [ ] }, { "dbId" : 10514547, "stId" : "R-SSC-5607724", "displayName" : "26S proteasome processes K48PolyUb-K21,22-p-S32,36-IkBA:NF-kB complex to form NF-kB complex", "schemaClass" : "BlackBoxEvent", "speciesId" : 0, "following" : [ 10505433 ], "inputs" : [ 10514545 ], "outputs" : [ 10464103 ], "catalysts" : [ 10447709 ], "efs" : [ ], "diagramIds" : [ 113443 ], "entityFunctionalStatus" : [ ] }, { "dbId" : 10478347, "stId" : "R-SSC-430190", "displayName" : "p-SLP-76 binds NCK", "schemaClass" : "Reaction", "speciesId" : 0, "inputs" : [ 10466903, 10471070 ], "outputs" : [ 10478341 ], "efs" : [ ], "diagramIds" : [ 113437 ], "entityFunctionalStatus" : [ ] }, { "dbId" : 10466826, "stId" : "R-SSC-202165", "displayName" : "Phosphorylation of ITAM motifs in CD3 complexes", "schemaClass" : "Reaction", "speciesId" : 0, "preceding" : [ 10466978 ], "inputs" : [ 113592, 10466793 ], "outputs" : [ 29370, 10466823 ], "catalysts" : [ 10466793 ], "efs" : [ ], "diagramIds" : [ 113296 ], "entityFunctionalStatus" : [ ] }, { "dbId" : 10478345, "stId" : "R-SSC-430183", "displayName" : "NCK binds PAK", "schemaClass" : "Reaction", "speciesId" : 0, "inputs" : [ 10478341, 10474630 ], "outputs" : [ 10478343 ], "efs" : [ ], "diagramIds" : [ 113440 ], "entityFunctionalStatus" : [ ] }, { "dbId" : 10466886, "stId" : "R-SSC-202214", "displayName" : "Dephosphorylation of Lck-pY505 by CD45", "schemaClass" : "Reaction", "speciesId" : 0, "preceding" : [ 10466930 ], "following" : [ 10466978 ], "inputs" : [ 29356, 10466875 ], "outputs" : [ 29372, 10466879 ], "catalysts" : [ 10466883 ], "efs" : [ ], "diagramIds" : [ 113289 ], "entityFunctionalStatus" : [ ] }, { "dbId" : 10467010, "stId" : "R-SSC-202394", "displayName" : "Translocation of CARMA1 to Plasma membrane", "schemaClass" : "Reaction", "speciesId" : 0, "preceding" : [ 10466923 ], "following" : [ 10467028 ], "inputs" : [ 10466714, 10467006 ], "outputs" : [ 10467008 ], "efs" : [ ], "diagramIds" : [ 113383 ], "entityFunctionalStatus" : [ ] }, { "dbId" : 10467074, "stId" : "R-SSC-202489", "displayName" : "Oligomerization of Bcl10", "schemaClass" : "Reaction", "speciesId" : 0, "preceding" : [ 10467066 ], "following" : [ 10467072 ], "inputs" : [ 10467063, 10467037 ], "outputs" : [ 10467039 ], "efs" : [ ], "diagramIds" : [ 113401 ], "entityFunctionalStatus" : [ ] }, { "dbId" : 10466944, "stId" : "R-SSC-202245", "displayName" : "Phosphorylation of TBSMs in LAT", "schemaClass" : "Reaction", "speciesId" : 0, "preceding" : [ 10466844 ], "following" : [ 10466870, 10466986 ], "inputs" : [ 113592, 10466942 ], "outputs" : [ 10466866, 29370 ], "catalysts" : [ 10466841 ], "efs" : [ ], "diagramIds" : [ 113309 ], "entityFunctionalStatus" : [ ] }, { "dbId" : 10467072, "stId" : "R-SSC-202478", "displayName" : "Interaction and oligomerization of MALT1 to Bcl10", "schemaClass" : "Reaction", "speciesId" : 0, "preceding" : [ 10467074 ], "following" : [ 10467070 ], "inputs" : [ 10467045, 10467039 ], "outputs" : [ 10467047 ], "efs" : [ ], "diagramIds" : [ 113404 ], "entityFunctionalStatus" : [ ] }, { "dbId" : 10467070, "stId" : "R-SSC-202472", "displayName" : "Translocation of TRAF6 to CBM complex", "schemaClass" : "Reaction", "speciesId" : 0, "preceding" : [ 10467072 ], "following" : [ 10467057 ], "inputs" : [ 10459233, 10467047 ], "outputs" : [ 10467049 ], "efs" : [ ], "diagramIds" : [ 113407 ], "entityFunctionalStatus" : [ ] }, { "dbId" : 10478333, "stId" : "R-SSC-430135", "displayName" : "p-SLP-76 binds ADAP", "schemaClass" : "Reaction", "speciesId" : 0, "preceding" : [ 10466908 ], "inputs" : [ 10475011, 10466903 ], "outputs" : [ 10478331 ], "efs" : [ ], "diagramIds" : [ 113433 ], "entityFunctionalStatus" : [ ] }, { "dbId" : 10466940, "stId" : "R-SSC-202241", "displayName" : "Recruitment of SLP-76 to Gads", "schemaClass" : "Reaction", "speciesId" : 0, "preceding" : [ 10466986 ], "following" : [ 10466908 ], "inputs" : [ 10466896, 10466892 ], "outputs" : [ 10466898 ], "efs" : [ ], "diagramIds" : [ 113317 ], "entityFunctionalStatus" : [ ] }, { "dbId" : 10467068, "stId" : "R-SSC-202466", "displayName" : "Interaction of Bcl10 to CARMA1", "schemaClass" : "Reaction", "speciesId" : 0, "preceding" : [ 10467032 ], "following" : [ 10467066 ], "inputs" : [ 10467059, 10467030 ], "outputs" : [ 10467061 ], "efs" : [ ], "diagramIds" : [ 113393 ], "entityFunctionalStatus" : [ ] }, { "dbId" : 10467515, "stId" : "R-SSC-203774", "displayName" : "Interaction of Csk with PAG", "schemaClass" : "Reaction", "speciesId" : 0, "following" : [ 10466930 ], "inputs" : [ 10462113, 10466925 ], "outputs" : [ 10466927 ], "efs" : [ ], "diagramIds" : [ 113279 ], "entityFunctionalStatus" : [ ] }, { "dbId" : 10467002, "stId" : "R-SSC-202375", "displayName" : "Recruitment of ITK to SLP-76", "schemaClass" : "Reaction", "speciesId" : 0, "preceding" : [ 10466908 ], "following" : [ 10466974 ], "inputs" : [ 10466963, 10466905 ], "outputs" : [ 10466965 ], "efs" : [ ], "diagramIds" : [ 113324 ], "entityFunctionalStatus" : [ ] }, { "dbId" : 10466938, "stId" : "R-SSC-202237", "displayName" : "Hydrolysis of PIP3 to PI(3,4)P2", "schemaClass" : "Reaction", "speciesId" : 0, "preceding" : [ 10467000 ], "following" : [ 10466716 ], "inputs" : [ 29356, 179838 ], "outputs" : [ 29372, 202247 ], "catalysts" : [ 10466935 ], "efs" : [ ], "diagramIds" : [ 113361 ], "entityFunctionalStatus" : [ ] }, { "dbId" : 10467066, "stId" : "R-SSC-202459", "displayName" : "Phosphorylation of Bcl10", "schemaClass" : "Reaction", "speciesId" : 0, "preceding" : [ 10467068 ], "following" : [ 10467074 ], "inputs" : [ 10467061, 113592 ], "outputs" : [ 29370, 10467063 ], "catalysts" : [ 10464013 ], "efs" : [ ], "diagramIds" : [ 113396 ], "entityFunctionalStatus" : [ ] }, { "dbId" : 10467000, "stId" : "R-SSC-202365", "displayName" : "PI3K bound to TRAT1 phosphorylates PIP2 to PIP3", "schemaClass" : "Reaction", "speciesId" : 0, "preceding" : [ 10466855 ], "following" : [ 10466716, 10466938 ], "inputs" : [ 113592, 179856 ], "outputs" : [ 179838, 29370 ], "catalysts" : [ 10466853 ], "efs" : [ ], "diagramIds" : [ 113356 ], "entityFunctionalStatus" : [ ] }, { "dbId" : 10466870, "stId" : "R-SSC-202212", "displayName" : "Recruitment of PLC-gamma1 to LAT", "schemaClass" : "Reaction", "speciesId" : 0, "preceding" : [ 10466944 ], "following" : [ 10466974 ], "inputs" : [ 10466866, 10466857 ], "outputs" : [ 10466868 ], "efs" : [ ], "diagramIds" : [ 113330 ], "entityFunctionalStatus" : [ ] }, { "dbId" : 10466997, "stId" : "R-SSC-202354", "displayName" : "Translocation of PLC-gamma1 to PIP2", "schemaClass" : "Reaction", "speciesId" : 0, "preceding" : [ 10469553, 10469555, 10466974 ], "following" : [ 10467020 ], "inputs" : [ 10466953, 179856 ], "outputs" : [ 10466995 ], "efs" : [ ], "diagramIds" : [ 113344 ], "entityFunctionalStatus" : [ ] }, { "dbId" : 10469555, "stId" : "R-SSC-213407", "displayName" : "Disassociation of PLC-gamma1 from SLP-76", "schemaClass" : "Reaction", "speciesId" : 0, "preceding" : [ 10466974 ], "following" : [ 10466997 ], "inputs" : [ 10466957 ], "outputs" : [ 10466905, 10466953 ], "efs" : [ ], "diagramIds" : [ 113342 ], "entityFunctionalStatus" : [ ] }, { "dbId" : 10466930, "stId" : "R-SSC-202233", "displayName" : "Inactivation of Lck by Csk", "schemaClass" : "Reaction", "speciesId" : 0, "preceding" : [ 10467515 ], "following" : [ 10466886 ], "inputs" : [ 113592, 10466879 ], "outputs" : [ 29370, 10466875 ], "catalysts" : [ 10466927 ], "efs" : [ ], "inhibitors" : [ 10466883 ], "diagramIds" : [ 113283 ], "entityFunctionalStatus" : [ ] }, { "dbId" : 10469553, "stId" : "R-SSC-213406", "displayName" : "Disassociation of PLC-gamma1 from LAT", "schemaClass" : "Reaction", "speciesId" : 0, "preceding" : [ 10466974 ], "following" : [ 10466997 ], "inputs" : [ 10466955 ], "outputs" : [ 10466866, 10466953 ], "efs" : [ ], "diagramIds" : [ 113339 ], "entityFunctionalStatus" : [ ] }, { "dbId" : 10467057, "stId" : "R-SSC-202453", "displayName" : "Auto-ubiquitination of TRAF6", "schemaClass" : "Reaction", "speciesId" : 0, "preceding" : [ 10467070 ], "following" : [ 10467103 ], "inputs" : [ 10459568, 10459538, 10467049 ], "outputs" : [ 10459568, 10467054 ], "catalysts" : [ 10467049 ], "efs" : [ ], "diagramIds" : [ 113410 ], "entityFunctionalStatus" : [ ] }, { "dbId" : 10467119, "stId" : "R-SSC-202541", "displayName" : "p-S177,S181-IKKB:IKKA:pUb-NEMO phosphorylates IkB-alpha:NF-kB", "schemaClass" : "Reaction", "speciesId" : 0, "preceding" : [ 10467114 ], "inputs" : [ 113592, 10464134 ], "outputs" : [ 29370, 10467116 ], "catalysts" : [ 10467111 ], "efs" : [ ], "diagramIds" : [ 113428 ], "entityFunctionalStatus" : [ ] }, { "dbId" : 10466990, "stId" : "R-SSC-202331", "displayName" : "Recruitment of PLC-gamma1 to SLP-76", "schemaClass" : "Reaction", "speciesId" : 0, "preceding" : [ 10466908 ], "following" : [ 10466974 ], "inputs" : [ 10466905, 10466857 ], "outputs" : [ 10466946 ], "efs" : [ ], "diagramIds" : [ 113327 ], "entityFunctionalStatus" : [ ] }, { "dbId" : 10466988, "stId" : "R-SSC-202328", "displayName" : "Translocation of PKC theta to plasma membrane", "schemaClass" : "Reaction", "speciesId" : 0, "preceding" : [ 10466716 ], "following" : [ 10466984 ], "inputs" : [ 112275, 10466335 ], "outputs" : [ 10466982 ], "efs" : [ ], "diagramIds" : [ 113370 ], "entityFunctionalStatus" : [ ] }, { "dbId" : 10466923, "stId" : "R-SSC-202222", "displayName" : "Phosphorylation of PKC theta", "schemaClass" : "Reaction", "speciesId" : 0, "preceding" : [ 10466984 ], "following" : [ 10467010 ], "inputs" : [ 10466913, 113592 ], "outputs" : [ 29370, 10466920 ], "catalysts" : [ 10466714 ], "efs" : [ ], "diagramIds" : [ 113379 ], "entityFunctionalStatus" : [ ] }, { "dbId" : 10466986, "stId" : "R-SSC-202325", "displayName" : "Recruitment of Gads to LAT", "schemaClass" : "Reaction", "speciesId" : 0, "preceding" : [ 10466944 ], "following" : [ 10466940 ], "inputs" : [ 10466866, 10466890 ], "outputs" : [ 10466892 ], "efs" : [ ], "diagramIds" : [ 113314 ], "entityFunctionalStatus" : [ ] }, { "dbId" : 10467114, "stId" : "R-SSC-202534", "displayName" : "Ubiquitination of NEMO by TRAF6", "schemaClass" : "BlackBoxEvent", "speciesId" : 0, "preceding" : [ 10467095 ], "following" : [ 10467119 ], "inputs" : [ 10459568, 10459538, 10467078 ], "outputs" : [ 10459568, 10467111 ], "catalysts" : [ 10467054 ], "efs" : [ ], "diagramIds" : [ 113424 ], "entityFunctionalStatus" : [ ] }, { "dbId" : 10466984, "stId" : "R-SSC-202307", "displayName" : "Change of PKC theta conformation", "schemaClass" : "Reaction", "speciesId" : 0, "preceding" : [ 10466988 ], "following" : [ 10466923 ], "inputs" : [ 113592, 10466982 ], "outputs" : [ 10466913, 29370 ], "catalysts" : [ 10466793 ], "efs" : [ ], "diagramIds" : [ 113374 ], "entityFunctionalStatus" : [ ] }, { "dbId" : 10466855, "stId" : "R-SSC-202203", "displayName" : "Recruitment of PI3K to plasma membrane", "schemaClass" : "Reaction", "speciesId" : 0, "preceding" : [ 10467020 ], "following" : [ 10467000 ], "inputs" : [ 10466851, 10451791 ], "outputs" : [ 10466853 ], "efs" : [ ], "diagramIds" : [ 113352 ], "entityFunctionalStatus" : [ ] }, { "dbId" : 10505433, "stId" : "R-SSC-2730894", "displayName" : "NFKB1:RELA translocates from the cytosol to the nucleus", "schemaClass" : "BlackBoxEvent", "speciesId" : 0, "preceding" : [ 10514547 ], "inputs" : [ 10464103 ], "outputs" : [ 10464105 ], "efs" : [ ], "diagramIds" : [ 113447 ], "entityFunctionalStatus" : [ ] }, { "dbId" : 10466978, "stId" : "R-SSC-202291", "displayName" : "Activation of Lck", "schemaClass" : "Reaction", "speciesId" : 0, "preceding" : [ 10466886 ], "following" : [ 10533989, 10466826 ], "inputs" : [ 113592, 10466879 ], "outputs" : [ 29370, 10466793 ], "catalysts" : [ 10466879 ], "efs" : [ ], "diagramIds" : [ 113292 ], "entityFunctionalStatus" : [ ] }, { "dbId" : 10465696, "stId" : "R-SSC-199456", "displayName" : "PTEN dephosphorylates PIP3", "schemaClass" : "Reaction", "speciesId" : 0, "inputs" : [ 29356, 179838 ], "outputs" : [ 29372, 179856 ], "catalysts" : [ 10465693 ], "efs" : [ ], "diagramIds" : [ 113457 ], "entityFunctionalStatus" : [ ] } ], "subpathways" : [ { "dbId" : 10556903, "stId" : "R-SSC-202427", "displayName" : "Phosphorylation of CD3 and TCR zeta chains", "events" : [ 10534626, 10467515, 10533989, 10466826, 10466886, 10466930, 10466978 ] }, { "dbId" : 10556907, "stId" : "R-SSC-202433", "displayName" : "Generation of second messenger molecules", "events" : [ 10466974, 10478333, 10466940, 10466908, 10467002, 10466870, 10466997, 10469555, 10469553, 10466990, 10467020, 10478347, 10466986, 10478345, 10466944 ] }, { "dbId" : 10556905, "stId" : "R-SSC-202430", "displayName" : "Translocation of ZAP-70 to Immunological synapse", "events" : [ 10466844, 10534628, 10466837 ] }, { "dbId" : 10556863, "stId" : "R-SSC-202424", "displayName" : "Downstream TCR signaling", "events" : [ 10467103, 10467070, 10466716, 10467068, 10466938, 10467066, 10467000, 10467032, 10467095, 10467028, 10467057, 10467119, 10466988, 10514547, 10466923, 10467114, 10466984, 10466855, 10505433, 10467010, 10467074, 10465696, 10467072 ] } ] }