{ "dbId" : 10444382, "stableId" : "R-BTA-68875", "displayName" : "Mitotic Prophase", "nodes" : [ { "id" : 25350, "reactomeId" : 10387403, "displayName" : "ARPP19", "schemaClass" : "EntityWithAccessionedSequence", "renderableClass" : "Protein", "position" : { "x" : 1047, "y" : 1017 }, "minX" : 1017, "maxX" : 1104, "minY" : 1001, "maxY" : 1028, "prop" : { "x" : 1017, "y" : 1007, "width" : 61, "height" : 21 }, "textPosition" : { "x" : 1019, "y" : 1007 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1078, "y" : 1007 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1078, "y" : 1007 } } }, "connectors" : [ { "edgeId" : 25349, "type" : "INPUT", "segments" : [ { "from" : { "x" : 1081, "y" : 1014 }, "to" : { "x" : 1104, "y" : 1012 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 25351, "reactomeId" : 29358, "displayName" : "ATP", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 1105, "y" : 973 }, "minX" : 1089, "maxX" : 1123, "minY" : 961, "maxY" : 1012, "prop" : { "x" : 1089, "y" : 962, "width" : 33, "height" : 23 }, "textPosition" : { "x" : 1090, "y" : 963 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1117, "y" : 967 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1117, "y" : 967 } } }, "connectors" : [ { "edgeId" : 25349, "type" : "INPUT", "segments" : [ { "from" : { "x" : 1104, "y" : 988 }, "to" : { "x" : 1104, "y" : 1012 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 25352, "reactomeId" : 113582, "displayName" : "ADP", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 1190, "y" : 984 }, "minX" : 1142, "maxX" : 1209, "minY" : 971, "maxY" : 1013, "prop" : { "x" : 1173, "y" : 972, "width" : 35, "height" : 25 }, "textPosition" : { "x" : 1174, "y" : 974 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1203, "y" : 977 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1203, "y" : 977 } } }, "connectors" : [ { "edgeId" : 25349, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 1170, "y" : 994 }, "to" : { "x" : 1142, "y" : 1013 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 1167, "y" : 1001 }, "b" : { "x" : 1170, "y" : 994 }, "c" : { "x" : 1162, "y" : 995 }, "type" : "ARROW", "centre" : { "x" : 1162, "y" : 995 } } } ] }, { "id" : 25353, "reactomeId" : 10387406, "displayName" : "phospho-ARPP19", "schemaClass" : "EntityWithAccessionedSequence", "renderableClass" : "Protein", "position" : { "x" : 1222, "y" : 1037 }, "minX" : 1142, "maxX" : 1279, "minY" : 1013, "maxY" : 1049, "prop" : { "x" : 1171, "y" : 1026, "width" : 102, "height" : 23 }, "textPosition" : { "x" : 1188, "y" : 1020 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1273, "y" : 1026 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1273, "y" : 1026 } } }, "connectors" : [ { "edgeId" : 25349, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 1183, "y" : 1023 }, "to" : { "x" : 1142, "y" : 1013 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 1175, "y" : 1025 }, "b" : { "x" : 1183, "y" : 1023 }, "c" : { "x" : 1177, "y" : 1017 }, "type" : "ARROW", "centre" : { "x" : 1177, "y" : 1017 } } } ] }, { "id" : 25354, "reactomeId" : 10387413, "displayName" : "phospho-MASTL", "schemaClass" : "EntityWithAccessionedSequence", "renderableClass" : "Protein", "position" : { "x" : 1004, "y" : 1056 }, "minX" : 911, "maxX" : 1133, "minY" : 1020, "maxY" : 1098, "prop" : { "x" : 911, "y" : 1042, "width" : 187, "height" : 28 }, "textPosition" : { "x" : 951, "y" : 1045 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1098, "y" : 1042 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1098, "y" : 1042 } } }, "connectors" : [ { "edgeId" : 25349, "type" : "CATALYST", "segments" : [ { "from" : { "x" : 1101, "y" : 1053 }, "to" : { "x" : 1133, "y" : 1053 } }, { "from" : { "x" : 1133, "y" : 1053 }, "to" : { "x" : 1128, "y" : 1028 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "c" : { "x" : 1127, "y" : 1024 }, "r" : 4, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1127, "y" : 1024 } } }, { "edgeId" : 25405, "type" : "CATALYST", "segments" : [ { "from" : { "x" : 1063, "y" : 1073 }, "to" : { "x" : 1110, "y" : 1081 } }, { "from" : { "x" : 1110, "y" : 1081 }, "to" : { "x" : 1112, "y" : 1090 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "c" : { "x" : 1113, "y" : 1094 }, "r" : 4, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1113, "y" : 1094 } } } ] }, { "id" : 25356, "reactomeId" : 10387631, "displayName" : "Condensin II", "schemaClass" : "Complex", "renderableClass" : "Complex", "position" : { "x" : 704, "y" : 706 }, "minX" : 648, "maxX" : 826, "minY" : 689, "maxY" : 901, "prop" : { "x" : 653, "y" : 695, "width" : 102, "height" : 22 }, "textPosition" : { "x" : 662, "y" : 696 }, "bgColor" : { "r" : 204, "g" : 255, "b" : 255 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 755, "y" : 695 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 755, "y" : 695 } } }, "connectors" : [ { "edgeId" : 25355, "type" : "INPUT", "segments" : [ { "from" : { "x" : 682, "y" : 720 }, "to" : { "x" : 648, "y" : 734 } } ], "stoichiometry" : { "value" : 1 } }, { "edgeId" : 25373, "type" : "INPUT", "segments" : [ { "from" : { "x" : 703, "y" : 720 }, "to" : { "x" : 699, "y" : 901 } } ], "stoichiometry" : { "value" : 1 } }, { "edgeId" : 25401, "type" : "INPUT", "segments" : [ { "from" : { "x" : 758, "y" : 706 }, "to" : { "x" : 826, "y" : 706 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 25357, "reactomeId" : 10333582, "displayName" : "RB1", "schemaClass" : "EntityWithAccessionedSequence", "renderableClass" : "Protein", "position" : { "x" : 594, "y" : 707 }, "minX" : 576, "maxX" : 648, "minY" : 690, "maxY" : 734, "prop" : { "x" : 576, "y" : 696, "width" : 36, "height" : 22 }, "textPosition" : { "x" : 578, "y" : 696 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 612, "y" : 696 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 612, "y" : 696 } } }, "connectors" : [ { "edgeId" : 25355, "type" : "INPUT", "segments" : [ { "from" : { "x" : 615, "y" : 716 }, "to" : { "x" : 648, "y" : 734 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 25358, "reactomeId" : 10387633, "displayName" : "Condensin II:RB1", "schemaClass" : "Complex", "renderableClass" : "Complex", "position" : { "x" : 650, "y" : 776 }, "minX" : 609, "maxX" : 715, "minY" : 754, "maxY" : 892, "prop" : { "x" : 609, "y" : 760, "width" : 83, "height" : 33 }, "textPosition" : { "x" : 611, "y" : 758 }, "bgColor" : { "r" : 204, "g" : 255, "b" : 255 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 692, "y" : 760 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 692, "y" : 760 } } }, "connectors" : [ { "edgeId" : 25355, "type" : "OUTPUT", "segments" : [ ], "stoichiometry" : { "value" : 1 } }, { "edgeId" : 25373, "type" : "ACTIVATOR", "segments" : [ { "from" : { "x" : 656, "y" : 796 }, "to" : { "x" : 715, "y" : 892 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 708, "y" : 888 }, "b" : { "x" : 715, "y" : 892 }, "c" : { "x" : 715, "y" : 884 }, "type" : "ARROW", "empty" : true, "centre" : { "x" : 715, "y" : 884 } } } ] }, { "id" : 25360, "reactomeId" : 113685, "displayName" : "O2", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 306, "y" : 949 }, "minX" : 289, "maxX" : 325, "minY" : 934, "maxY" : 997, "prop" : { "x" : 289, "y" : 935, "width" : 35, "height" : 28 }, "textPosition" : { "x" : 294, "y" : 938 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 319, "y" : 940 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 319, "y" : 940 } } }, "connectors" : [ { "edgeId" : 25359, "type" : "INPUT", "segments" : [ { "from" : { "x" : 307, "y" : 966 }, "to" : { "x" : 311, "y" : 997 } } ], "stoichiometry" : { "value" : 1 } } ], "trivial" : true }, { "id" : 25361, "reactomeId" : 113671, "displayName" : "2OG", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 261, "y" : 977 }, "minX" : 241, "maxX" : 311, "minY" : 964, "maxY" : 997, "prop" : { "x" : 241, "y" : 965, "width" : 40, "height" : 25 }, "textPosition" : { "x" : 244, "y" : 967 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 276, "y" : 970 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 276, "y" : 970 } } }, "connectors" : [ { "edgeId" : 25359, "type" : "INPUT", "segments" : [ { "from" : { "x" : 284, "y" : 985 }, "to" : { "x" : 311, "y" : 997 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 25362, "reactomeId" : 10387668, "displayName" : "PHF8:Nucleosome with H3K4me2/3:H4K20me1", "schemaClass" : "Complex", "renderableClass" : "Complex", "position" : { "x" : 368, "y" : 893 }, "minX" : 305, "maxX" : 460, "minY" : 862, "maxY" : 1027, "prop" : { "x" : 305, "y" : 868, "width" : 126, "height" : 50 }, "textPosition" : { "x" : 305, "y" : 869 }, "bgColor" : { "r" : 204, "g" : 255, "b" : 255 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 431, "y" : 868 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 431, "y" : 868 } } }, "connectors" : [ { "edgeId" : 25359, "type" : "INPUT", "segments" : [ { "from" : { "x" : 354, "y" : 921 }, "to" : { "x" : 311, "y" : 997 } } ], "stoichiometry" : { "value" : 1 } }, { "edgeId" : 25359, "type" : "CATALYST", "segments" : [ { "from" : { "x" : 368, "y" : 921 }, "to" : { "x" : 368, "y" : 1021 } }, { "from" : { "x" : 368, "y" : 1021 }, "to" : { "x" : 328, "y" : 1022 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "c" : { "x" : 324, "y" : 1023 }, "r" : 4, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 324, "y" : 1023 } } }, { "edgeId" : 25367, "type" : "INPUT", "segments" : [ { "from" : { "x" : 434, "y" : 896 }, "to" : { "x" : 460, "y" : 898 } } ], "stoichiometry" : { "value" : 1 } }, { "edgeId" : 25386, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 375, "y" : 921 }, "to" : { "x" : 386, "y" : 951 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 381, "y" : 926 }, "b" : { "x" : 375, "y" : 921 }, "c" : { "x" : 374, "y" : 929 }, "type" : "ARROW", "centre" : { "x" : 374, "y" : 929 } } } ] }, { "id" : 25363, "reactomeId" : 159942, "displayName" : "CO2", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 271, "y" : 1049 }, "minX" : 250, "maxX" : 314, "minY" : 1036, "maxY" : 1062, "prop" : { "x" : 250, "y" : 1037, "width" : 42, "height" : 25 }, "textPosition" : { "x" : 254, "y" : 1039 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 287, "y" : 1042 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 287, "y" : 1042 } } }, "connectors" : [ { "edgeId" : 25359, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 295, "y" : 1053 }, "to" : { "x" : 314, "y" : 1059 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 303, "y" : 1051 }, "b" : { "x" : 295, "y" : 1053 }, "c" : { "x" : 300, "y" : 1059 }, "type" : "ARROW", "centre" : { "x" : 300, "y" : 1059 } } } ], "trivial" : true }, { "id" : 25364, "reactomeId" : 159939, "displayName" : "SUCCA", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 272, "y" : 1093 }, "minX" : 244, "maxX" : 314, "minY" : 1059, "maxY" : 1106, "prop" : { "x" : 244, "y" : 1081, "width" : 56, "height" : 25 }, "textPosition" : { "x" : 247, "y" : 1083 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 295, "y" : 1086 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 295, "y" : 1086 } } }, "connectors" : [ { "edgeId" : 25359, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 287, "y" : 1078 }, "to" : { "x" : 314, "y" : 1059 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 290, "y" : 1071 }, "b" : { "x" : 287, "y" : 1078 }, "c" : { "x" : 295, "y" : 1077 }, "type" : "ARROW", "centre" : { "x" : 295, "y" : 1077 } } } ] }, { "id" : 25365, "reactomeId" : 10387672, "displayName" : "PHF8:Nucleosome with H3K4me2/3", "schemaClass" : "Complex", "renderableClass" : "Complex", "position" : { "x" : 389, "y" : 1097 }, "minX" : 314, "maxX" : 458, "minY" : 1052, "maxY" : 1115, "prop" : { "x" : 326, "y" : 1079, "width" : 126, "height" : 36 }, "textPosition" : { "x" : 326, "y" : 1080 }, "bgColor" : { "r" : 204, "g" : 255, "b" : 255 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 452, "y" : 1079 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 452, "y" : 1079 } } }, "connectors" : [ { "edgeId" : 25359, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 353, "y" : 1076 }, "to" : { "x" : 314, "y" : 1059 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 345, "y" : 1077 }, "b" : { "x" : 353, "y" : 1076 }, "c" : { "x" : 348, "y" : 1070 }, "type" : "ARROW", "centre" : { "x" : 348, "y" : 1070 } } }, { "edgeId" : 25386, "type" : "INPUT", "segments" : [ { "from" : { "x" : 390, "y" : 1076 }, "to" : { "x" : 392, "y" : 1052 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 25366, "reactomeId" : 29478, "displayName" : "CH2O", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 315, "y" : 1136 }, "minX" : 284, "maxX" : 347, "minY" : 1059, "maxY" : 1148, "prop" : { "x" : 284, "y" : 1124, "width" : 62, "height" : 24 }, "textPosition" : { "x" : 294, "y" : 1125 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 341, "y" : 1129 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 341, "y" : 1129 } } }, "connectors" : [ { "edgeId" : 25359, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 314, "y" : 1121 }, "to" : { "x" : 314, "y" : 1059 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 310, "y" : 1114 }, "b" : { "x" : 314, "y" : 1121 }, "c" : { "x" : 318, "y" : 1114 }, "type" : "ARROW", "centre" : { "x" : 318, "y" : 1114 } } } ] }, { "id" : 25368, "reactomeId" : 29358, "displayName" : "ATP", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 447, "y" : 823 }, "minX" : 429, "maxX" : 466, "minY" : 810, "maxY" : 898, "prop" : { "x" : 429, "y" : 811, "width" : 36, "height" : 24 }, "textPosition" : { "x" : 431, "y" : 812 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 460, "y" : 816 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 460, "y" : 816 } } }, "connectors" : [ { "edgeId" : 25367, "type" : "INPUT", "segments" : [ { "from" : { "x" : 449, "y" : 838 }, "to" : { "x" : 460, "y" : 898 } } ], "stoichiometry" : { "value" : 2, "shape" : { "a" : { "x" : 448, "y" : 862 }, "b" : { "x" : 460, "y" : 874 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 454, "y" : 868 } } } } ] }, { "id" : 25369, "reactomeId" : 10387656, "displayName" : "Nucleosome with H3K4me2/3:H4K20me1", "schemaClass" : "Complex", "renderableClass" : "Complex", "position" : { "x" : 582, "y" : 902 }, "minX" : 494, "maxX" : 699, "minY" : 871, "maxY" : 927, "prop" : { "x" : 523, "y" : 877, "width" : 119, "height" : 50 }, "textPosition" : { "x" : 523, "y" : 878 }, "bgColor" : { "r" : 204, "g" : 255, "b" : 255 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 642, "y" : 877 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 642, "y" : 877 } } }, "connectors" : [ { "edgeId" : 25367, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 520, "y" : 899 }, "to" : { "x" : 494, "y" : 899 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 513, "y" : 903 }, "b" : { "x" : 520, "y" : 899 }, "c" : { "x" : 513, "y" : 895 }, "type" : "ARROW", "centre" : { "x" : 513, "y" : 895 } } }, { "edgeId" : 25373, "type" : "INPUT", "segments" : [ { "from" : { "x" : 645, "y" : 901 }, "to" : { "x" : 699, "y" : 901 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 25370, "reactomeId" : 10388285, "displayName" : "p-2S-PHF8:Fe2+", "schemaClass" : "Complex", "renderableClass" : "Complex", "position" : { "x" : 589, "y" : 818 }, "minX" : 494, "maxX" : 635, "minY" : 796, "maxY" : 899, "prop" : { "x" : 549, "y" : 802, "width" : 80, "height" : 32 }, "textPosition" : { "x" : 551, "y" : 799 }, "bgColor" : { "r" : 204, "g" : 255, "b" : 255 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 629, "y" : 802 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 629, "y" : 802 } } }, "connectors" : [ { "edgeId" : 25367, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 570, "y" : 837 }, "to" : { "x" : 494, "y" : 899 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 567, "y" : 844 }, "b" : { "x" : 570, "y" : 837 }, "c" : { "x" : 562, "y" : 838 }, "type" : "ARROW", "centre" : { "x" : 562, "y" : 838 } } } ] }, { "id" : 25371, "reactomeId" : 113582, "displayName" : "ADP", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 507, "y" : 823 }, "minX" : 489, "maxX" : 527, "minY" : 810, "maxY" : 899, "prop" : { "x" : 489, "y" : 811, "width" : 37, "height" : 25 }, "textPosition" : { "x" : 491, "y" : 813 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 521, "y" : 816 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 521, "y" : 816 } } }, "connectors" : [ { "edgeId" : 25367, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 504, "y" : 839 }, "to" : { "x" : 494, "y" : 899 } } ], "stoichiometry" : { "value" : 2, "shape" : { "a" : { "x" : 493, "y" : 863 }, "b" : { "x" : 505, "y" : 875 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 499, "y" : 869 } } }, "endShape" : { "a" : { "x" : 507, "y" : 846 }, "b" : { "x" : 504, "y" : 839 }, "c" : { "x" : 499, "y" : 845 }, "type" : "ARROW", "centre" : { "x" : 499, "y" : 845 } } } ] }, { "id" : 25372, "reactomeId" : 10345739, "displayName" : "CCNB1:p-T161-CDK1", "schemaClass" : "Complex", "renderableClass" : "Complex", "position" : { "x" : 696, "y" : 964 }, "minX" : 247, "maxX" : 919, "minY" : 906, "maxY" : 1323, "prop" : { "x" : 623, "y" : 952, "width" : 146, "height" : 24 }, "textPosition" : { "x" : 630, "y" : 955 }, "bgColor" : { "r" : 204, "g" : 255, "b" : 255 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 769, "y" : 952 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 769, "y" : 952 } } }, "connectors" : [ { "edgeId" : 25474, "type" : "CATALYST", "segments" : [ { "from" : { "x" : 703, "y" : 979 }, "to" : { "x" : 844, "y" : 1206 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "c" : { "x" : 846, "y" : 1210 }, "r" : 4, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 846, "y" : 1210 } } }, { "edgeId" : 25367, "type" : "CATALYST", "segments" : [ { "from" : { "x" : 620, "y" : 963 }, "to" : { "x" : 477, "y" : 963 } }, { "from" : { "x" : 477, "y" : 963 }, "to" : { "x" : 478, "y" : 914 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "c" : { "x" : 478, "y" : 910 }, "r" : 4, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 478, "y" : 910 } } }, { "edgeId" : 25375, "type" : "CATALYST", "segments" : [ { "from" : { "x" : 772, "y" : 963 }, "to" : { "x" : 915, "y" : 963 } }, { "from" : { "x" : 915, "y" : 963 }, "to" : { "x" : 915, "y" : 915 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "c" : { "x" : 915, "y" : 911 }, "r" : 4, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 915, "y" : 911 } } }, { "edgeId" : 25453, "type" : "CATALYST", "segments" : [ { "from" : { "x" : 620, "y" : 968 }, "to" : { "x" : 584, "y" : 971 } }, { "from" : { "x" : 584, "y" : 971 }, "to" : { "x" : 556, "y" : 1299 } }, { "from" : { "x" : 556, "y" : 1299 }, "to" : { "x" : 286, "y" : 1297 } }, { "from" : { "x" : 286, "y" : 1297 }, "to" : { "x" : 255, "y" : 1317 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "c" : { "x" : 251, "y" : 1319 }, "r" : 4, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 251, "y" : 1319 } } }, { "edgeId" : 25470, "type" : "CATALYST", "segments" : [ { "from" : { "x" : 620, "y" : 966 }, "to" : { "x" : 520, "y" : 970 } }, { "from" : { "x" : 520, "y" : 970 }, "to" : { "x" : 477, "y" : 1145 } }, { "from" : { "x" : 477, "y" : 1145 }, "to" : { "x" : 370, "y" : 1148 } }, { "from" : { "x" : 370, "y" : 1148 }, "to" : { "x" : 369, "y" : 1167 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "c" : { "x" : 369, "y" : 1171 }, "r" : 4, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 369, "y" : 1171 } } } ] }, { "id" : 25374, "reactomeId" : 10388339, "displayName" : "Condensin II:Nucleosome with H4K20me1", "schemaClass" : "Complex", "renderableClass" : "Complex", "position" : { "x" : 799, "y" : 899 }, "minX" : 745, "maxX" : 887, "minY" : 868, "maxY" : 924, "prop" : { "x" : 745, "y" : 874, "width" : 109, "height" : 50 }, "textPosition" : { "x" : 747, "y" : 875 }, "bgColor" : { "r" : 204, "g" : 255, "b" : 255 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 854, "y" : 874 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 854, "y" : 874 } } }, "connectors" : [ { "edgeId" : 25373, "type" : "OUTPUT", "segments" : [ ], "stoichiometry" : { "value" : 1 } }, { "edgeId" : 25375, "type" : "INPUT", "segments" : [ { "from" : { "x" : 857, "y" : 898 }, "to" : { "x" : 887, "y" : 898 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 25376, "reactomeId" : 29358, "displayName" : "ATP", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 864, "y" : 848 }, "minX" : 846, "maxX" : 887, "minY" : 835, "maxY" : 898, "prop" : { "x" : 846, "y" : 836, "width" : 37, "height" : 25 }, "textPosition" : { "x" : 849, "y" : 838 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 878, "y" : 841 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 878, "y" : 841 } } }, "connectors" : [ { "edgeId" : 25375, "type" : "INPUT", "segments" : [ { "from" : { "x" : 869, "y" : 864 }, "to" : { "x" : 887, "y" : 898 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 25377, "reactomeId" : 113582, "displayName" : "ADP", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 948, "y" : 846 }, "minX" : 930, "maxX" : 967, "minY" : 833, "maxY" : 899, "prop" : { "x" : 930, "y" : 834, "width" : 36, "height" : 24 }, "textPosition" : { "x" : 931, "y" : 835 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 961, "y" : 839 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 961, "y" : 839 } } }, "connectors" : [ { "edgeId" : 25375, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 945, "y" : 861 }, "to" : { "x" : 935, "y" : 899 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 947, "y" : 869 }, "b" : { "x" : 945, "y" : 861 }, "c" : { "x" : 939, "y" : 867 }, "type" : "ARROW", "centre" : { "x" : 939, "y" : 867 } } } ] }, { "id" : 25378, "reactomeId" : 10388367, "displayName" : "Phosphorylated Condensin II:Nucleosome", "schemaClass" : "Complex", "renderableClass" : "Complex", "position" : { "x" : 1021, "y" : 899 }, "minX" : 935, "maxX" : 1112, "minY" : 871, "maxY" : 922, "prop" : { "x" : 966, "y" : 877, "width" : 110, "height" : 45 }, "textPosition" : { "x" : 966, "y" : 873 }, "bgColor" : { "r" : 204, "g" : 255, "b" : 255 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1076, "y" : 877 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1076, "y" : 877 } } }, "connectors" : [ { "edgeId" : 25375, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 963, "y" : 899 }, "to" : { "x" : 935, "y" : 899 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 956, "y" : 903 }, "b" : { "x" : 963, "y" : 899 }, "c" : { "x" : 956, "y" : 895 }, "type" : "ARROW", "centre" : { "x" : 956, "y" : 895 } } }, { "edgeId" : 25379, "type" : "INPUT", "segments" : [ { "from" : { "x" : 1079, "y" : 897 }, "to" : { "x" : 1112, "y" : 896 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 25380, "reactomeId" : 10342926, "displayName" : "phospho-p-T210-PLK1", "schemaClass" : "EntityWithAccessionedSequence", "renderableClass" : "Protein", "position" : { "x" : 1087, "y" : 809 }, "minX" : 1036, "maxX" : 1144, "minY" : 790, "maxY" : 896, "prop" : { "x" : 1036, "y" : 796, "width" : 102, "height" : 26 }, "textPosition" : { "x" : 1047, "y" : 792 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1138, "y" : 796 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1138, "y" : 796 } } }, "connectors" : [ { "edgeId" : 25379, "type" : "INPUT", "segments" : [ { "from" : { "x" : 1090, "y" : 825 }, "to" : { "x" : 1112, "y" : 896 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 25381, "reactomeId" : 10388349, "displayName" : "p-T210-PLK1:Phosphorylated Condensin II:Nucleosome", "schemaClass" : "Complex", "renderableClass" : "Complex", "position" : { "x" : 1200, "y" : 896 }, "minX" : 1149, "maxX" : 1300, "minY" : 860, "maxY" : 926, "prop" : { "x" : 1149, "y" : 866, "width" : 103, "height" : 60 }, "textPosition" : { "x" : 1150, "y" : 863 }, "bgColor" : { "r" : 204, "g" : 255, "b" : 255 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1252, "y" : 866 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1252, "y" : 866 } } }, "connectors" : [ { "edgeId" : 25379, "type" : "OUTPUT", "segments" : [ ], "stoichiometry" : { "value" : 1 } }, { "edgeId" : 25382, "type" : "INPUT", "segments" : [ { "from" : { "x" : 1255, "y" : 897 }, "to" : { "x" : 1281, "y" : 899 } } ], "stoichiometry" : { "value" : 1 } }, { "edgeId" : 25382, "type" : "CATALYST", "segments" : [ { "from" : { "x" : 1255, "y" : 878 }, "to" : { "x" : 1283, "y" : 868 } }, { "from" : { "x" : 1283, "y" : 868 }, "to" : { "x" : 1294, "y" : 886 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "c" : { "x" : 1296, "y" : 890 }, "r" : 4, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1296, "y" : 890 } } } ] }, { "id" : 25383, "reactomeId" : 29358, "displayName" : "ATP", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 1266, "y" : 957 }, "minX" : 1247, "maxX" : 1287, "minY" : 899, "maxY" : 970, "prop" : { "x" : 1247, "y" : 944, "width" : 39, "height" : 26 }, "textPosition" : { "x" : 1251, "y" : 946 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1281, "y" : 949 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1281, "y" : 949 } } }, "connectors" : [ { "edgeId" : 25382, "type" : "INPUT", "segments" : [ { "from" : { "x" : 1269, "y" : 941 }, "to" : { "x" : 1281, "y" : 899 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 25384, "reactomeId" : 10388362, "displayName" : "Hyperphosphorylated Condensin II:Nucleosome", "schemaClass" : "Complex", "renderableClass" : "Complex", "position" : { "x" : 1595, "y" : 892 }, "minX" : 1320, "maxX" : 1668, "minY" : 862, "maxY" : 916, "prop" : { "x" : 1528, "y" : 868, "width" : 134, "height" : 48 }, "textPosition" : { "x" : 1528, "y" : 867 }, "bgColor" : { "r" : 204, "g" : 255, "b" : 255 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1662, "y" : 868 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1662, "y" : 868 } } }, "connectors" : [ { "edgeId" : 25382, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 1525, "y" : 893 }, "to" : { "x" : 1320, "y" : 900 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 1518, "y" : 897 }, "b" : { "x" : 1525, "y" : 893 }, "c" : { "x" : 1518, "y" : 889 }, "type" : "ARROW", "centre" : { "x" : 1518, "y" : 889 } } } ] }, { "id" : 25385, "reactomeId" : 113582, "displayName" : "ADP", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 1343, "y" : 963 }, "minX" : 1320, "maxX" : 1363, "minY" : 900, "maxY" : 976, "prop" : { "x" : 1325, "y" : 950, "width" : 37, "height" : 26 }, "textPosition" : { "x" : 1327, "y" : 952 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1357, "y" : 955 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1357, "y" : 955 } } }, "connectors" : [ { "edgeId" : 25382, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 1338, "y" : 947 }, "to" : { "x" : 1320, "y" : 900 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 1332, "y" : 942 }, "b" : { "x" : 1338, "y" : 947 }, "c" : { "x" : 1339, "y" : 939 }, "type" : "ARROW", "centre" : { "x" : 1339, "y" : 939 } } } ] }, { "id" : 25387, "reactomeId" : 77087, "displayName" : "AdoMet", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 436, "y" : 1051 }, "minX" : 392, "maxX" : 465, "minY" : 1035, "maxY" : 1066, "prop" : { "x" : 408, "y" : 1036, "width" : 56, "height" : 30 }, "textPosition" : { "x" : 408, "y" : 1040 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 459, "y" : 1041 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 459, "y" : 1041 } } }, "connectors" : [ { "edgeId" : 25386, "type" : "INPUT", "segments" : [ { "from" : { "x" : 405, "y" : 1051 }, "to" : { "x" : 392, "y" : 1052 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 25388, "reactomeId" : 77502, "displayName" : "AdoHcy", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 432, "y" : 946 }, "minX" : 386, "maxX" : 460, "minY" : 931, "maxY" : 961, "prop" : { "x" : 406, "y" : 932, "width" : 53, "height" : 29 }, "textPosition" : { "x" : 408, "y" : 929 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 454, "y" : 937 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 454, "y" : 937 } } }, "connectors" : [ { "edgeId" : 25386, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 403, "y" : 948 }, "to" : { "x" : 386, "y" : 951 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 397, "y" : 953 }, "b" : { "x" : 403, "y" : 948 }, "c" : { "x" : 395, "y" : 945 }, "type" : "ARROW", "centre" : { "x" : 395, "y" : 945 } } } ] }, { "id" : 25389, "reactomeId" : 10388379, "displayName" : "SETD8", "schemaClass" : "EntityWithAccessionedSequence", "renderableClass" : "Protein", "position" : { "x" : 448, "y" : 997 }, "minX" : 401, "maxX" : 480, "minY" : 980, "maxY" : 1008, "prop" : { "x" : 423, "y" : 986, "width" : 51, "height" : 22 }, "textPosition" : { "x" : 424, "y" : 986 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 474, "y" : 986 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 474, "y" : 986 } } }, "connectors" : [ { "edgeId" : 25386, "type" : "CATALYST", "segments" : [ { "from" : { "x" : 420, "y" : 997 }, "to" : { "x" : 409, "y" : 997 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "c" : { "x" : 405, "y" : 997 }, "r" : 4, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 405, "y" : 997 } } } ] }, { "id" : 25391, "reactomeId" : 113592, "displayName" : "ATP", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 977, "y" : 311 }, "minX" : 959, "maxX" : 997, "minY" : 221, "maxY" : 323, "prop" : { "x" : 959, "y" : 300, "width" : 37, "height" : 23 }, "textPosition" : { "x" : 962, "y" : 301 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 991, "y" : 305 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 991, "y" : 305 } } }, "connectors" : [ { "edgeId" : 25390, "type" : "INPUT", "segments" : [ { "from" : { "x" : 979, "y" : 297 }, "to" : { "x" : 994, "y" : 221 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 25392, "reactomeId" : 10388187, "displayName" : "p-T216,S274,S373-GORASP1:p-S37-GOLGA2:p-RAB1:GTP:p-T210-PLK1", "schemaClass" : "Complex", "renderableClass" : "Complex", "position" : { "x" : 904, "y" : 223 }, "minX" : 838, "maxX" : 1009, "minY" : 183, "maxY" : 257, "prop" : { "x" : 838, "y" : 189, "width" : 133, "height" : 68 }, "textPosition" : { "x" : 841, "y" : 194 }, "bgColor" : { "r" : 204, "g" : 255, "b" : 255 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 971, "y" : 189 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 971, "y" : 189 } } }, "connectors" : [ { "edgeId" : 25390, "type" : "INPUT", "segments" : [ { "from" : { "x" : 974, "y" : 221 }, "to" : { "x" : 994, "y" : 221 } } ], "stoichiometry" : { "value" : 1 } }, { "edgeId" : 25390, "type" : "CATALYST", "segments" : [ { "from" : { "x" : 974, "y" : 196 }, "to" : { "x" : 996, "y" : 187 } }, { "from" : { "x" : 996, "y" : 187 }, "to" : { "x" : 1004, "y" : 205 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "c" : { "x" : 1005, "y" : 209 }, "r" : 4, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1005, "y" : 209 } } } ] }, { "id" : 25393, "reactomeId" : 10388192, "displayName" : "p-T216,S189,S274,S373-GORASP1:p-S37-GOLGA2:p-RAB1:GTP:p-T210-PLK1", "schemaClass" : "Complex", "renderableClass" : "Complex", "position" : { "x" : 1155, "y" : 216 }, "minX" : 1027, "maxX" : 1236, "minY" : 179, "maxY" : 247, "prop" : { "x" : 1080, "y" : 185, "width" : 150, "height" : 62 }, "textPosition" : { "x" : 1080, "y" : 184 }, "bgColor" : { "r" : 204, "g" : 255, "b" : 255 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1230, "y" : 185 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1230, "y" : 185 } } }, "connectors" : [ { "edgeId" : 25390, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 1077, "y" : 218 }, "to" : { "x" : 1027, "y" : 221 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 1070, "y" : 222 }, "b" : { "x" : 1077, "y" : 218 }, "c" : { "x" : 1070, "y" : 214 }, "type" : "ARROW", "centre" : { "x" : 1070, "y" : 214 } } } ] }, { "id" : 25394, "reactomeId" : 29370, "displayName" : "ADP", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 1040, "y" : 309 }, "minX" : 1022, "maxX" : 1060, "minY" : 221, "maxY" : 321, "prop" : { "x" : 1022, "y" : 297, "width" : 37, "height" : 24 }, "textPosition" : { "x" : 1024, "y" : 298 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1054, "y" : 302 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1054, "y" : 302 } } }, "connectors" : [ { "edgeId" : 25390, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 1038, "y" : 294 }, "to" : { "x" : 1027, "y" : 221 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 1033, "y" : 288 }, "b" : { "x" : 1038, "y" : 294 }, "c" : { "x" : 1041, "y" : 287 }, "type" : "ARROW", "centre" : { "x" : 1041, "y" : 287 } } } ] }, { "id" : 25396, "reactomeId" : 113592, "displayName" : "ATP", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 594, "y" : 97 }, "minX" : 574, "maxX" : 629, "minY" : 81, "maxY" : 150, "prop" : { "x" : 574, "y" : 82, "width" : 40, "height" : 30 }, "textPosition" : { "x" : 578, "y" : 86 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 609, "y" : 87 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 609, "y" : 87 } } }, "connectors" : [ { "edgeId" : 25395, "type" : "INPUT", "segments" : [ { "from" : { "x" : 603, "y" : 115 }, "to" : { "x" : 629, "y" : 150 } } ], "stoichiometry" : { "value" : 2, "shape" : { "a" : { "x" : 610, "y" : 126 }, "b" : { "x" : 622, "y" : 138 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 616, "y" : 132 } } } } ] }, { "id" : 25397, "reactomeId" : 10389016, "displayName" : "GORASP2:BLZF1:RAB2A:GTP", "schemaClass" : "Complex", "renderableClass" : "Complex", "position" : { "x" : 487, "y" : 149 }, "minX" : 396, "maxX" : 629, "minY" : 130, "maxY" : 162, "prop" : { "x" : 396, "y" : 136, "width" : 183, "height" : 26 }, "textPosition" : { "x" : 397, "y" : 141 }, "bgColor" : { "r" : 204, "g" : 255, "b" : 255 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 579, "y" : 136 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 579, "y" : 136 } } }, "connectors" : [ { "edgeId" : 25395, "type" : "INPUT", "segments" : [ { "from" : { "x" : 582, "y" : 149 }, "to" : { "x" : 629, "y" : 150 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 25398, "reactomeId" : 10389022, "displayName" : "p-T222,225-GORASP2:BLZF1:RAB2A:GTP", "schemaClass" : "Complex", "renderableClass" : "Complex", "position" : { "x" : 913, "y" : 151 }, "minX" : 730, "maxX" : 1048, "minY" : 132, "maxY" : 165, "prop" : { "x" : 784, "y" : 138, "width" : 258, "height" : 27 }, "textPosition" : { "x" : 785, "y" : 144 }, "bgColor" : { "r" : 204, "g" : 255, "b" : 255 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1042, "y" : 138 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1042, "y" : 138 } } }, "connectors" : [ { "edgeId" : 25395, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 781, "y" : 151 }, "to" : { "x" : 730, "y" : 151 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 774, "y" : 155 }, "b" : { "x" : 781, "y" : 151 }, "c" : { "x" : 774, "y" : 147 }, "type" : "ARROW", "centre" : { "x" : 774, "y" : 147 } } } ] }, { "id" : 25399, "reactomeId" : 29370, "displayName" : "ADP", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 747, "y" : 92 }, "minX" : 727, "maxX" : 769, "minY" : 76, "maxY" : 151, "prop" : { "x" : 727, "y" : 77, "width" : 41, "height" : 30 }, "textPosition" : { "x" : 731, "y" : 81 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 763, "y" : 82 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 763, "y" : 82 } } }, "connectors" : [ { "edgeId" : 25395, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 742, "y" : 110 }, "to" : { "x" : 730, "y" : 151 } } ], "stoichiometry" : { "value" : 2, "shape" : { "a" : { "x" : 730, "y" : 124 }, "b" : { "x" : 742, "y" : 136 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 736, "y" : 130 } } }, "endShape" : { "a" : { "x" : 744, "y" : 118 }, "b" : { "x" : 742, "y" : 110 }, "c" : { "x" : 736, "y" : 116 }, "type" : "ARROW", "centre" : { "x" : 736, "y" : 116 } } } ] }, { "id" : 25400, "reactomeId" : 10389028, "displayName" : "p-Y204-MAPK3-3/p-T185,Y187-MAPK1 homodimer", "schemaClass" : "CandidateSet", "renderableClass" : "EntitySet", "position" : { "x" : 675, "y" : 46 }, "minX" : 545, "maxX" : 806, "minY" : 28, "maxY" : 143, "prop" : { "x" : 545, "y" : 28, "width" : 261, "height" : 37 }, "textPosition" : { "x" : 556, "y" : 29 }, "bgColor" : { "r" : 204, "g" : 255, "b" : 255 }, "connectors" : [ { "edgeId" : 25395, "type" : "CATALYST", "segments" : [ { "from" : { "x" : 675, "y" : 71 }, "to" : { "x" : 677, "y" : 135 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "c" : { "x" : 677, "y" : 139 }, "r" : 4, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 677, "y" : 139 } } } ] }, { "id" : 25402, "reactomeId" : 10366517, "displayName" : "SET", "schemaClass" : "EntityWithAccessionedSequence", "renderableClass" : "Protein", "position" : { "x" : 823, "y" : 644 }, "minX" : 806, "maxX" : 846, "minY" : 629, "maxY" : 706, "prop" : { "x" : 806, "y" : 635, "width" : 34, "height" : 19 }, "textPosition" : { "x" : 807, "y" : 634 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 840, "y" : 635 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 840, "y" : 635 } } }, "connectors" : [ { "edgeId" : 25401, "type" : "INPUT", "segments" : [ { "from" : { "x" : 823, "y" : 657 }, "to" : { "x" : 826, "y" : 706 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 25403, "reactomeId" : 10389190, "displayName" : "MCPH1", "schemaClass" : "EntityWithAccessionedSequence", "renderableClass" : "Protein", "position" : { "x" : 766, "y" : 664 }, "minX" : 741, "maxX" : 826, "minY" : 648, "maxY" : 706, "prop" : { "x" : 741, "y" : 654, "width" : 51, "height" : 20 }, "textPosition" : { "x" : 741, "y" : 654 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 792, "y" : 654 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 792, "y" : 654 } } }, "connectors" : [ { "edgeId" : 25401, "type" : "INPUT", "segments" : [ { "from" : { "x" : 780, "y" : 677 }, "to" : { "x" : 826, "y" : 706 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 25404, "reactomeId" : 10389192, "displayName" : "Condensin II:MCPH1:SET", "schemaClass" : "Complex", "renderableClass" : "Complex", "position" : { "x" : 902, "y" : 705 }, "minX" : 858, "maxX" : 953, "minY" : 681, "maxY" : 723, "prop" : { "x" : 858, "y" : 687, "width" : 89, "height" : 36 }, "textPosition" : { "x" : 858, "y" : 688 }, "bgColor" : { "r" : 204, "g" : 255, "b" : 255 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 947, "y" : 687 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 947, "y" : 687 } } }, "connectors" : [ { "edgeId" : 25401, "type" : "OUTPUT", "segments" : [ ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 25406, "reactomeId" : 10389198, "displayName" : "ENSA", "schemaClass" : "EntityWithAccessionedSequence", "renderableClass" : "Protein", "position" : { "x" : 1044, "y" : 1114 }, "minX" : 1023, "maxX" : 1093, "minY" : 1097, "maxY" : 1125, "prop" : { "x" : 1023, "y" : 1103, "width" : 42, "height" : 22 }, "textPosition" : { "x" : 1023, "y" : 1103 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1065, "y" : 1103 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1065, "y" : 1103 } } }, "connectors" : [ { "edgeId" : 25405, "type" : "INPUT", "segments" : [ { "from" : { "x" : 1068, "y" : 1111 }, "to" : { "x" : 1093, "y" : 1108 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 25407, "reactomeId" : 29358, "displayName" : "ATP", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 1084, "y" : 1150 }, "minX" : 1066, "maxX" : 1103, "minY" : 1108, "maxY" : 1161, "prop" : { "x" : 1066, "y" : 1139, "width" : 36, "height" : 22 }, "textPosition" : { "x" : 1068, "y" : 1139 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1097, "y" : 1144 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1097, "y" : 1144 } } }, "connectors" : [ { "edgeId" : 25405, "type" : "INPUT", "segments" : [ { "from" : { "x" : 1086, "y" : 1136 }, "to" : { "x" : 1093, "y" : 1108 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 25408, "reactomeId" : 113582, "displayName" : "ADP", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 1162, "y" : 1149 }, "minX" : 1138, "maxX" : 1182, "minY" : 1106, "maxY" : 1162, "prop" : { "x" : 1144, "y" : 1136, "width" : 37, "height" : 26 }, "textPosition" : { "x" : 1146, "y" : 1138 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1176, "y" : 1141 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1176, "y" : 1141 } } }, "connectors" : [ { "edgeId" : 25405, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 1154, "y" : 1133 }, "to" : { "x" : 1138, "y" : 1106 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 1147, "y" : 1129 }, "b" : { "x" : 1154, "y" : 1133 }, "c" : { "x" : 1154, "y" : 1125 }, "type" : "ARROW", "centre" : { "x" : 1154, "y" : 1125 } } } ] }, { "id" : 25409, "reactomeId" : 10389201, "displayName" : "phospho-ENSA", "schemaClass" : "EntityWithAccessionedSequence", "renderableClass" : "Protein", "position" : { "x" : 1216, "y" : 1118 }, "minX" : 1138, "maxX" : 1269, "minY" : 1101, "maxY" : 1129, "prop" : { "x" : 1169, "y" : 1107, "width" : 94, "height" : 22 }, "textPosition" : { "x" : 1182, "y" : 1101 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1263, "y" : 1107 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1263, "y" : 1107 } } }, "connectors" : [ { "edgeId" : 25405, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 1166, "y" : 1110 }, "to" : { "x" : 1138, "y" : 1106 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 1159, "y" : 1113 }, "b" : { "x" : 1166, "y" : 1110 }, "c" : { "x" : 1160, "y" : 1105 }, "type" : "ARROW", "centre" : { "x" : 1160, "y" : 1105 } } } ] }, { "id" : 25411, "reactomeId" : 10390858, "displayName" : "p-T333-NEK9", "schemaClass" : "Complex", "renderableClass" : "Complex", "position" : { "x" : 179, "y" : 507 }, "minX" : 132, "maxX" : 263, "minY" : 490, "maxY" : 518, "prop" : { "x" : 132, "y" : 496, "width" : 95, "height" : 22 }, "textPosition" : { "x" : 136, "y" : 497 }, "bgColor" : { "r" : 204, "g" : 255, "b" : 255 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 227, "y" : 496 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 227, "y" : 496 } } }, "connectors" : [ { "edgeId" : 25410, "type" : "INPUT", "segments" : [ { "from" : { "x" : 230, "y" : 507 }, "to" : { "x" : 263, "y" : 507 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 25412, "reactomeId" : 113592, "displayName" : "ATP", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 243, "y" : 441 }, "minX" : 226, "maxX" : 263, "minY" : 429, "maxY" : 507, "prop" : { "x" : 226, "y" : 430, "width" : 35, "height" : 23 }, "textPosition" : { "x" : 228, "y" : 431 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 256, "y" : 435 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 256, "y" : 435 } } }, "connectors" : [ { "edgeId" : 25410, "type" : "INPUT", "segments" : [ { "from" : { "x" : 246, "y" : 456 }, "to" : { "x" : 263, "y" : 507 } } ], "stoichiometry" : { "value" : 6, "shape" : { "a" : { "x" : 248, "y" : 475 }, "b" : { "x" : 260, "y" : 487 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 254, "y" : 481 } } } } ] }, { "id" : 25413, "reactomeId" : 10390862, "displayName" : "p-3S,T-NEK9", "schemaClass" : "Complex", "renderableClass" : "Complex", "position" : { "x" : 537, "y" : 505 }, "minX" : 375, "maxX" : 774, "minY" : 486, "maxY" : 518, "prop" : { "x" : 489, "y" : 492, "width" : 97, "height" : 26 }, "textPosition" : { "x" : 496, "y" : 497 }, "bgColor" : { "r" : 204, "g" : 255, "b" : 255 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 586, "y" : 492 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 586, "y" : 492 } } }, "connectors" : [ { "edgeId" : 25410, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 486, "y" : 505 }, "to" : { "x" : 375, "y" : 506 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 479, "y" : 509 }, "b" : { "x" : 486, "y" : 505 }, "c" : { "x" : 479, "y" : 501 }, "type" : "ARROW", "centre" : { "x" : 479, "y" : 501 } } }, { "edgeId" : 25416, "type" : "INPUT", "segments" : [ { "from" : { "x" : 589, "y" : 505 }, "to" : { "x" : 774, "y" : 506 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 25414, "reactomeId" : 29370, "displayName" : "ADP", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 402, "y" : 458 }, "minX" : 375, "maxX" : 421, "minY" : 445, "maxY" : 506, "prop" : { "x" : 384, "y" : 446, "width" : 36, "height" : 24 }, "textPosition" : { "x" : 385, "y" : 447 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 415, "y" : 451 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 415, "y" : 451 } } }, "connectors" : [ { "edgeId" : 25410, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 395, "y" : 473 }, "to" : { "x" : 375, "y" : 506 } } ], "stoichiometry" : { "value" : 6, "shape" : { "a" : { "x" : 379, "y" : 483 }, "b" : { "x" : 391, "y" : 495 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 385, "y" : 489 } } }, "endShape" : { "a" : { "x" : 395, "y" : 481 }, "b" : { "x" : 395, "y" : 473 }, "c" : { "x" : 388, "y" : 477 }, "type" : "ARROW", "centre" : { "x" : 388, "y" : 477 } } } ] }, { "id" : 25415, "reactomeId" : 10345774, "displayName" : "CCNB1,CCNB2:p-T161-CDK1", "schemaClass" : "DefinedSet", "renderableClass" : "EntitySet", "position" : { "x" : 317, "y" : 332 }, "minX" : 266, "maxX" : 383, "minY" : 316, "maxY" : 599, "prop" : { "x" : 266, "y" : 316, "width" : 102, "height" : 33 }, "textPosition" : { "x" : 268, "y" : 315 }, "bgColor" : { "r" : 204, "g" : 255, "b" : 255 }, "connectors" : [ { "edgeId" : 25410, "type" : "CATALYST", "segments" : [ { "from" : { "x" : 317, "y" : 355 }, "to" : { "x" : 317, "y" : 490 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "c" : { "x" : 317, "y" : 494 }, "r" : 4, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 317, "y" : 494 } } }, { "edgeId" : 25428, "type" : "CATALYST", "segments" : [ { "from" : { "x" : 320, "y" : 355 }, "to" : { "x" : 378, "y" : 591 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "c" : { "x" : 379, "y" : 595 }, "r" : 4, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 379, "y" : 595 } } } ] }, { "id" : 25417, "reactomeId" : 113592, "displayName" : "ATP", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 745, "y" : 453 }, "minX" : 724, "maxX" : 774, "minY" : 440, "maxY" : 506, "prop" : { "x" : 724, "y" : 441, "width" : 43, "height" : 24 }, "textPosition" : { "x" : 730, "y" : 442 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 762, "y" : 446 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 762, "y" : 446 } } }, "connectors" : [ { "edgeId" : 25416, "type" : "INPUT", "segments" : [ { "from" : { "x" : 751, "y" : 468 }, "to" : { "x" : 774, "y" : 506 } } ], "stoichiometry" : { "value" : 2, "shape" : { "a" : { "x" : 756, "y" : 481 }, "b" : { "x" : 768, "y" : 493 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 762, "y" : 487 } } } } ] }, { "id" : 25418, "reactomeId" : 10390840, "displayName" : "p-3S,2T-NEK9", "schemaClass" : "Complex", "renderableClass" : "Complex", "position" : { "x" : 967, "y" : 503 }, "minX" : 877, "maxX" : 1055, "minY" : 486, "maxY" : 515, "prop" : { "x" : 915, "y" : 492, "width" : 104, "height" : 23 }, "textPosition" : { "x" : 921, "y" : 494 }, "bgColor" : { "r" : 204, "g" : 255, "b" : 255 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1019, "y" : 492 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1019, "y" : 492 } } }, "connectors" : [ { "edgeId" : 25416, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 912, "y" : 504 }, "to" : { "x" : 877, "y" : 505 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 905, "y" : 508 }, "b" : { "x" : 912, "y" : 504 }, "c" : { "x" : 905, "y" : 500 }, "type" : "ARROW", "centre" : { "x" : 905, "y" : 500 } } }, { "edgeId" : 25421, "type" : "INPUT", "segments" : [ { "from" : { "x" : 1022, "y" : 501 }, "to" : { "x" : 1055, "y" : 500 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 25419, "reactomeId" : 29370, "displayName" : "ADP", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 909, "y" : 445 }, "minX" : 877, "maxX" : 930, "minY" : 432, "maxY" : 505, "prop" : { "x" : 890, "y" : 433, "width" : 39, "height" : 25 }, "textPosition" : { "x" : 893, "y" : 435 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 924, "y" : 438 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 924, "y" : 438 } } }, "connectors" : [ { "edgeId" : 25416, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 902, "y" : 461 }, "to" : { "x" : 877, "y" : 505 } } ], "stoichiometry" : { "value" : 2, "shape" : { "a" : { "x" : 883, "y" : 477 }, "b" : { "x" : 895, "y" : 489 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 889, "y" : 483 } } }, "endShape" : { "a" : { "x" : 902, "y" : 469 }, "b" : { "x" : 902, "y" : 461 }, "c" : { "x" : 895, "y" : 465 }, "type" : "ARROW", "centre" : { "x" : 895, "y" : 465 } } } ] }, { "id" : 25420, "reactomeId" : 10342936, "displayName" : "phospho-p-T210-PLK1", "schemaClass" : "EntityWithAccessionedSequence", "renderableClass" : "Protein", "position" : { "x" : 827, "y" : 391 }, "minX" : 776, "maxX" : 885, "minY" : 373, "maxY" : 498, "prop" : { "x" : 776, "y" : 379, "width" : 103, "height" : 24 }, "textPosition" : { "x" : 788, "y" : 374 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 879, "y" : 379 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 879, "y" : 379 } } }, "connectors" : [ { "edgeId" : 25416, "type" : "CATALYST", "segments" : [ { "from" : { "x" : 826, "y" : 406 }, "to" : { "x" : 826, "y" : 490 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "c" : { "x" : 826, "y" : 494 }, "r" : 4, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 826, "y" : 494 } } } ] }, { "id" : 25422, "reactomeId" : 10390829, "displayName" : "NEK6/NEK7", "schemaClass" : "CandidateSet", "renderableClass" : "EntitySet", "position" : { "x" : 1031, "y" : 446 }, "minX" : 1007, "maxX" : 1055, "minY" : 428, "maxY" : 500, "prop" : { "x" : 1007, "y" : 428, "width" : 48, "height" : 37 }, "textPosition" : { "x" : 1009, "y" : 429 }, "connectors" : [ { "edgeId" : 25421, "type" : "INPUT", "segments" : [ { "from" : { "x" : 1039, "y" : 471 }, "to" : { "x" : 1055, "y" : 500 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 25423, "reactomeId" : 10390842, "displayName" : "p-3S,2T-NEK9:NEK6/NEK7", "schemaClass" : "Complex", "renderableClass" : "Complex", "position" : { "x" : 1138, "y" : 499 }, "minX" : 1084, "maxX" : 1249, "minY" : 472, "maxY" : 525, "prop" : { "x" : 1084, "y" : 478, "width" : 108, "height" : 43 }, "textPosition" : { "x" : 1090, "y" : 486 }, "bgColor" : { "r" : 204, "g" : 255, "b" : 255 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1192, "y" : 478 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1192, "y" : 478 } } }, "connectors" : [ { "edgeId" : 25421, "type" : "OUTPUT", "segments" : [ ], "stoichiometry" : { "value" : 1 } }, { "edgeId" : 25424, "type" : "INPUT", "segments" : [ { "from" : { "x" : 1195, "y" : 498 }, "to" : { "x" : 1224, "y" : 498 } } ], "stoichiometry" : { "value" : 1 } }, { "edgeId" : 25424, "type" : "CATALYST", "segments" : [ { "from" : { "x" : 1195, "y" : 513 }, "to" : { "x" : 1234, "y" : 525 } }, { "from" : { "x" : 1234, "y" : 525 }, "to" : { "x" : 1242, "y" : 512 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "c" : { "x" : 1245, "y" : 508 }, "r" : 4, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1245, "y" : 508 } } } ] }, { "id" : 25425, "reactomeId" : 113592, "displayName" : "ATP", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 1203, "y" : 423 }, "minX" : 1184, "maxX" : 1224, "minY" : 409, "maxY" : 498, "prop" : { "x" : 1184, "y" : 410, "width" : 39, "height" : 27 }, "textPosition" : { "x" : 1188, "y" : 413 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1218, "y" : 415 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1218, "y" : 415 } } }, "connectors" : [ { "edgeId" : 25424, "type" : "INPUT", "segments" : [ { "from" : { "x" : 1206, "y" : 440 }, "to" : { "x" : 1224, "y" : 498 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 25426, "reactomeId" : 10390876, "displayName" : "p-3S,2T-NEK9: p-S206-NEK6/ p-S195-NEK7", "schemaClass" : "Complex", "renderableClass" : "Complex", "position" : { "x" : 1371, "y" : 501 }, "minX" : 1277, "maxX" : 1435, "minY" : 471, "maxY" : 594, "prop" : { "x" : 1314, "y" : 477, "width" : 115, "height" : 49 }, "textPosition" : { "x" : 1316, "y" : 477 }, "bgColor" : { "r" : 204, "g" : 255, "b" : 255 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1429, "y" : 477 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1429, "y" : 477 } } }, "connectors" : [ { "edgeId" : 25424, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 1311, "y" : 499 }, "to" : { "x" : 1277, "y" : 498 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 1304, "y" : 503 }, "b" : { "x" : 1311, "y" : 499 }, "c" : { "x" : 1304, "y" : 495 }, "type" : "ARROW", "centre" : { "x" : 1304, "y" : 495 } } }, { "edgeId" : 25433, "type" : "CATALYST", "segments" : [ { "from" : { "x" : 1370, "y" : 529 }, "to" : { "x" : 1370, "y" : 586 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "c" : { "x" : 1370, "y" : 590 }, "r" : 4, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1370, "y" : 590 } } } ] }, { "id" : 25427, "reactomeId" : 29370, "displayName" : "ADP", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 1312, "y" : 419 }, "minX" : 1277, "maxX" : 1334, "minY" : 404, "maxY" : 498, "prop" : { "x" : 1291, "y" : 405, "width" : 42, "height" : 28 }, "textPosition" : { "x" : 1295, "y" : 408 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1328, "y" : 410 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1328, "y" : 410 } } }, "connectors" : [ { "edgeId" : 25424, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 1305, "y" : 436 }, "to" : { "x" : 1277, "y" : 498 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 1306, "y" : 444 }, "b" : { "x" : 1305, "y" : 436 }, "c" : { "x" : 1299, "y" : 441 }, "type" : "ARROW", "centre" : { "x" : 1299, "y" : 441 } } } ] }, { "id" : 25429, "reactomeId" : 113592, "displayName" : "ATP", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 311, "y" : 558 }, "minX" : 291, "maxX" : 345, "minY" : 545, "maxY" : 606, "prop" : { "x" : 291, "y" : 546, "width" : 41, "height" : 25 }, "textPosition" : { "x" : 296, "y" : 548 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 327, "y" : 551 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 327, "y" : 551 } } }, "connectors" : [ { "edgeId" : 25428, "type" : "INPUT", "segments" : [ { "from" : { "x" : 319, "y" : 574 }, "to" : { "x" : 345, "y" : 606 } } ], "stoichiometry" : { "value" : 40, "shape" : { "a" : { "x" : 326, "y" : 584 }, "b" : { "x" : 338, "y" : 596 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 332, "y" : 590 } } } } ] }, { "id" : 25430, "reactomeId" : 10338233, "displayName" : "Nuclear Pore Complex (NPC)", "schemaClass" : "Complex", "renderableClass" : "Complex", "position" : { "x" : 217, "y" : 606 }, "minX" : 144, "maxX" : 345, "minY" : 580, "maxY" : 626, "prop" : { "x" : 144, "y" : 586, "width" : 147, "height" : 40 }, "textPosition" : { "x" : 143, "y" : 591 }, "bgColor" : { "r" : 204, "g" : 255, "b" : 255 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 291, "y" : 586 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 291, "y" : 586 } } }, "connectors" : [ { "edgeId" : 25428, "type" : "INPUT", "segments" : [ { "from" : { "x" : 294, "y" : 606 }, "to" : { "x" : 345, "y" : 606 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 25431, "reactomeId" : 10390954, "displayName" : "Nuclear Pore Complex (p-2S,3T-NUP98)", "schemaClass" : "Complex", "renderableClass" : "Complex", "position" : { "x" : 1027, "y" : 604 }, "minX" : 439, "maxX" : 1277, "minY" : 573, "maxY" : 629, "prop" : { "x" : 956, "y" : 579, "width" : 143, "height" : 50 }, "textPosition" : { "x" : 967, "y" : 580 }, "bgColor" : { "r" : 204, "g" : 255, "b" : 255 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1099, "y" : 579 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1099, "y" : 579 } } }, "connectors" : [ { "edgeId" : 25428, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 953, "y" : 604 }, "to" : { "x" : 439, "y" : 606 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 946, "y" : 608 }, "b" : { "x" : 953, "y" : 604 }, "c" : { "x" : 946, "y" : 600 }, "type" : "ARROW", "centre" : { "x" : 946, "y" : 600 } } }, { "edgeId" : 25433, "type" : "INPUT", "segments" : [ { "from" : { "x" : 1102, "y" : 603 }, "to" : { "x" : 1277, "y" : 601 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 25432, "reactomeId" : 29370, "displayName" : "ADP", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 466, "y" : 553 }, "minX" : 439, "maxX" : 489, "minY" : 539, "maxY" : 606, "prop" : { "x" : 444, "y" : 540, "width" : 44, "height" : 26 }, "textPosition" : { "x" : 449, "y" : 542 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 483, "y" : 545 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 483, "y" : 545 } } }, "connectors" : [ { "edgeId" : 25428, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 459, "y" : 569 }, "to" : { "x" : 439, "y" : 606 } } ], "stoichiometry" : { "value" : 40, "shape" : { "a" : { "x" : 443, "y" : 581 }, "b" : { "x" : 455, "y" : 593 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 449, "y" : 587 } } }, "endShape" : { "a" : { "x" : 459, "y" : 577 }, "b" : { "x" : 459, "y" : 569 }, "c" : { "x" : 452, "y" : 573 }, "type" : "ARROW", "centre" : { "x" : 452, "y" : 573 } } } ] }, { "id" : 25434, "reactomeId" : 113592, "displayName" : "ATP", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 1254, "y" : 558 }, "minX" : 1234, "maxX" : 1277, "minY" : 544, "maxY" : 601, "prop" : { "x" : 1234, "y" : 545, "width" : 41, "height" : 27 }, "textPosition" : { "x" : 1239, "y" : 548 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1270, "y" : 550 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1270, "y" : 550 } } }, "connectors" : [ { "edgeId" : 25433, "type" : "INPUT", "segments" : [ { "from" : { "x" : 1261, "y" : 575 }, "to" : { "x" : 1277, "y" : 601 } } ], "stoichiometry" : { "value" : 16, "shape" : { "a" : { "x" : 1263, "y" : 582 }, "b" : { "x" : 1275, "y" : 594 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 1269, "y" : 588 } } } } ] }, { "id" : 25435, "reactomeId" : 29370, "displayName" : "ADP", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 1501, "y" : 541 }, "minX" : 1434, "maxX" : 1521, "minY" : 528, "maxY" : 603, "prop" : { "x" : 1482, "y" : 529, "width" : 38, "height" : 24 }, "textPosition" : { "x" : 1484, "y" : 530 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1515, "y" : 534 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1515, "y" : 534 } } }, "connectors" : [ { "edgeId" : 25433, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 1488, "y" : 556 }, "to" : { "x" : 1434, "y" : 603 } } ], "stoichiometry" : { "value" : 16, "shape" : { "a" : { "x" : 1455, "y" : 573 }, "b" : { "x" : 1467, "y" : 585 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 1461, "y" : 579 } } }, "endShape" : { "a" : { "x" : 1485, "y" : 564 }, "b" : { "x" : 1488, "y" : 556 }, "c" : { "x" : 1480, "y" : 558 }, "type" : "ARROW", "centre" : { "x" : 1480, "y" : 558 } } } ] }, { "id" : 25436, "reactomeId" : 10390966, "displayName" : "phospho-NUP98", "schemaClass" : "EntityWithAccessionedSequence", "renderableClass" : "Protein", "position" : { "x" : 1488, "y" : 676 }, "minX" : 1434, "maxX" : 1547, "minY" : 603, "maxY" : 687, "prop" : { "x" : 1436, "y" : 665, "width" : 105, "height" : 22 }, "textPosition" : { "x" : 1455, "y" : 659 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1541, "y" : 665 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1541, "y" : 665 } } }, "connectors" : [ { "edgeId" : 25433, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 1479, "y" : 659 }, "to" : { "x" : 1434, "y" : 603 } } ], "stoichiometry" : { "value" : 4, "shape" : { "a" : { "x" : 1450, "y" : 625 }, "b" : { "x" : 1462, "y" : 637 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 1456, "y" : 631 } } }, "endShape" : { "a" : { "x" : 1472, "y" : 656 }, "b" : { "x" : 1479, "y" : 659 }, "c" : { "x" : 1478, "y" : 651 }, "type" : "ARROW", "centre" : { "x" : 1478, "y" : 651 } } } ] }, { "id" : 25437, "reactomeId" : 10390956, "displayName" : "Partially Disassembled NPC", "schemaClass" : "Complex", "renderableClass" : "Complex", "position" : { "x" : 1529, "y" : 601 }, "minX" : 1434, "maxX" : 1582, "minY" : 571, "maxY" : 625, "prop" : { "x" : 1482, "y" : 577, "width" : 94, "height" : 48 }, "textPosition" : { "x" : 1485, "y" : 576 }, "bgColor" : { "r" : 204, "g" : 255, "b" : 255 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1576, "y" : 577 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1576, "y" : 577 } } }, "connectors" : [ { "edgeId" : 25433, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 1479, "y" : 601 }, "to" : { "x" : 1434, "y" : 603 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 1472, "y" : 605 }, "b" : { "x" : 1479, "y" : 601 }, "c" : { "x" : 1472, "y" : 597 }, "type" : "ARROW", "centre" : { "x" : 1472, "y" : 597 } } } ] }, { "id" : 25438, "reactomeId" : 10390960, "displayName" : "phospho-NUP98", "schemaClass" : "EntityWithAccessionedSequence", "renderableClass" : "Protein", "position" : { "x" : 1484, "y" : 462 }, "minX" : 1432, "maxX" : 1543, "minY" : 445, "maxY" : 603, "prop" : { "x" : 1432, "y" : 451, "width" : 105, "height" : 22 }, "textPosition" : { "x" : 1451, "y" : 445 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1537, "y" : 451 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1537, "y" : 451 } } }, "connectors" : [ { "edgeId" : 25433, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 1480, "y" : 479 }, "to" : { "x" : 1434, "y" : 603 } } ], "stoichiometry" : { "value" : 4, "shape" : { "a" : { "x" : 1451, "y" : 535 }, "b" : { "x" : 1463, "y" : 547 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 1457, "y" : 541 } } }, "endShape" : { "a" : { "x" : 1481, "y" : 487 }, "b" : { "x" : 1480, "y" : 479 }, "c" : { "x" : 1474, "y" : 484 }, "type" : "ARROW", "centre" : { "x" : 1474, "y" : 484 } } } ] }, { "id" : 25440, "reactomeId" : 29358, "displayName" : "ATP", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 204, "y" : 730 }, "minX" : 148, "maxX" : 223, "minY" : 718, "maxY" : 743, "prop" : { "x" : 187, "y" : 719, "width" : 35, "height" : 23 }, "textPosition" : { "x" : 189, "y" : 720 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 217, "y" : 724 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 217, "y" : 724 } } }, "connectors" : [ { "edgeId" : 25439, "type" : "INPUT", "segments" : [ { "from" : { "x" : 184, "y" : 733 }, "to" : { "x" : 148, "y" : 741 } } ], "stoichiometry" : { "value" : 6, "shape" : { "a" : { "x" : 160, "y" : 731 }, "b" : { "x" : 172, "y" : 743 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 166, "y" : 737 } } } } ] }, { "id" : 25441, "reactomeId" : 10391085, "displayName" : "EMD/TMPO/LEMD3/LEMD2:Lamin filaments:BANF1:Chromatin", "schemaClass" : "Complex", "renderableClass" : "Complex", "position" : { "x" : 150, "y" : 673 }, "minX" : 87, "maxX" : 220, "minY" : 637, "maxY" : 741, "prop" : { "x" : 87, "y" : 643, "width" : 127, "height" : 61 }, "textPosition" : { "x" : 89, "y" : 641 }, "bgColor" : { "r" : 204, "g" : 255, "b" : 255 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 214, "y" : 643 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 214, "y" : 643 } } }, "connectors" : [ { "edgeId" : 25439, "type" : "INPUT", "segments" : [ { "from" : { "x" : 149, "y" : 707 }, "to" : { "x" : 148, "y" : 741 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 25442, "reactomeId" : 113582, "displayName" : "ADP", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 222, "y" : 871 }, "minX" : 150, "maxX" : 244, "minY" : 846, "maxY" : 882, "prop" : { "x" : 202, "y" : 860, "width" : 41, "height" : 22 }, "textPosition" : { "x" : 206, "y" : 860 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 238, "y" : 865 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 238, "y" : 865 } } }, "connectors" : [ { "edgeId" : 25439, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 199, "y" : 863 }, "to" : { "x" : 150, "y" : 846 } } ], "stoichiometry" : { "value" : 6, "shape" : { "a" : { "x" : 168, "y" : 848 }, "b" : { "x" : 180, "y" : 860 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 174, "y" : 854 } } }, "endShape" : { "a" : { "x" : 191, "y" : 865 }, "b" : { "x" : 199, "y" : 863 }, "c" : { "x" : 194, "y" : 857 }, "type" : "ARROW", "centre" : { "x" : 194, "y" : 857 } } } ] }, { "id" : 25443, "reactomeId" : 10391087, "displayName" : "EMD/TMPO/LEMD3/LEMD2:Lamin filaments", "schemaClass" : "Complex", "renderableClass" : "Complex", "position" : { "x" : 140, "y" : 909 }, "minX" : 75, "maxX" : 211, "minY" : 846, "maxY" : 961, "prop" : { "x" : 75, "y" : 885, "width" : 130, "height" : 48 }, "textPosition" : { "x" : 76, "y" : 884 }, "bgColor" : { "r" : 204, "g" : 255, "b" : 255 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 205, "y" : 885 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 205, "y" : 885 } } }, "connectors" : [ { "edgeId" : 25439, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 143, "y" : 882 }, "to" : { "x" : 150, "y" : 846 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 140, "y" : 874 }, "b" : { "x" : 143, "y" : 882 }, "c" : { "x" : 148, "y" : 876 }, "type" : "ARROW", "centre" : { "x" : 148, "y" : 876 } } }, { "edgeId" : 25465, "type" : "INPUT", "segments" : [ { "from" : { "x" : 139, "y" : 936 }, "to" : { "x" : 139, "y" : 961 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 25444, "reactomeId" : 10391094, "displayName" : "p-T2,T3,S4-BANF1", "schemaClass" : "Complex", "renderableClass" : "Complex", "position" : { "x" : 251, "y" : 810 }, "minX" : 150, "maxX" : 321, "minY" : 794, "maxY" : 846, "prop" : { "x" : 187, "y" : 800, "width" : 128, "height" : 20 }, "textPosition" : { "x" : 192, "y" : 799 }, "bgColor" : { "r" : 204, "g" : 255, "b" : 255 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 315, "y" : 800 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 315, "y" : 800 } } }, "connectors" : [ { "edgeId" : 25439, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 222, "y" : 823 }, "to" : { "x" : 150, "y" : 846 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 217, "y" : 829 }, "b" : { "x" : 222, "y" : 823 }, "c" : { "x" : 214, "y" : 821 }, "type" : "ARROW", "centre" : { "x" : 214, "y" : 821 } } } ] }, { "id" : 25445, "reactomeId" : 2537690, "displayName" : "Chromatin", "schemaClass" : "DefinedSet", "renderableClass" : "EntitySet", "position" : { "x" : 291, "y" : 844 }, "minX" : 150, "maxX" : 328, "minY" : 833, "maxY" : 855, "prop" : { "x" : 255, "y" : 833, "width" : 73, "height" : 22 }, "textPosition" : { "x" : 255, "y" : 833 }, "connectors" : [ { "edgeId" : 25439, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 249, "y" : 844 }, "to" : { "x" : 150, "y" : 846 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 242, "y" : 848 }, "b" : { "x" : 249, "y" : 844 }, "c" : { "x" : 242, "y" : 840 }, "type" : "ARROW", "centre" : { "x" : 242, "y" : 840 } } } ] }, { "id" : 25446, "reactomeId" : 10391104, "displayName" : "VRK1/VRK2", "schemaClass" : "CandidateSet", "renderableClass" : "EntitySet", "position" : { "x" : 272, "y" : 771 }, "minX" : 157, "maxX" : 312, "minY" : 760, "maxY" : 782, "prop" : { "x" : 233, "y" : 760, "width" : 79, "height" : 22 }, "textPosition" : { "x" : 235, "y" : 760 }, "connectors" : [ { "edgeId" : 25439, "type" : "CATALYST", "segments" : [ { "from" : { "x" : 227, "y" : 772 }, "to" : { "x" : 165, "y" : 774 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "c" : { "x" : 161, "y" : 775 }, "r" : 4, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 161, "y" : 775 } } } ] }, { "id" : 25448, "reactomeId" : 113518, "displayName" : "H2O", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 281, "y" : 1395 }, "minX" : 256, "maxX" : 303, "minY" : 1382, "maxY" : 1425, "prop" : { "x" : 261, "y" : 1383, "width" : 41, "height" : 24 }, "textPosition" : { "x" : 264, "y" : 1384 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 297, "y" : 1388 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 297, "y" : 1388 } } }, "connectors" : [ { "edgeId" : 25447, "type" : "INPUT", "segments" : [ { "from" : { "x" : 271, "y" : 1410 }, "to" : { "x" : 256, "y" : 1425 } } ], "stoichiometry" : { "value" : 1 } } ], "trivial" : true }, { "id" : 25449, "reactomeId" : 10396013, "displayName" : "p-S106-LPIN", "schemaClass" : "CandidateSet", "renderableClass" : "EntitySet", "position" : { "x" : 355, "y" : 1426 }, "minX" : 256, "maxX" : 385, "minY" : 1328, "maxY" : 1444, "prop" : { "x" : 325, "y" : 1408, "width" : 60, "height" : 36 }, "textPosition" : { "x" : 327, "y" : 1408 }, "connectors" : [ { "edgeId" : 25447, "type" : "INPUT", "segments" : [ { "from" : { "x" : 319, "y" : 1425 }, "to" : { "x" : 256, "y" : 1425 } } ], "stoichiometry" : { "value" : 1 } }, { "edgeId" : 25453, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 342, "y" : 1402 }, "to" : { "x" : 285, "y" : 1328 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 335, "y" : 1399 }, "b" : { "x" : 342, "y" : 1402 }, "c" : { "x" : 341, "y" : 1394 }, "type" : "ARROW", "centre" : { "x" : 341, "y" : 1394 } } } ] }, { "id" : 25450, "reactomeId" : 10396021, "displayName" : "LPIN", "schemaClass" : "CandidateSet", "renderableClass" : "EntitySet", "position" : { "x" : 98, "y" : 1425 }, "minX" : 81, "maxX" : 209, "minY" : 1271, "maxY" : 1436, "prop" : { "x" : 81, "y" : 1414, "width" : 34, "height" : 22 }, "textPosition" : { "x" : 81, "y" : 1414 }, "connectors" : [ { "edgeId" : 25447, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 121, "y" : 1425 }, "to" : { "x" : 204, "y" : 1425 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 128, "y" : 1421 }, "b" : { "x" : 121, "y" : 1425 }, "c" : { "x" : 128, "y" : 1429 }, "type" : "ARROW", "centre" : { "x" : 128, "y" : 1429 } } }, { "edgeId" : 25453, "type" : "INPUT", "segments" : [ { "from" : { "x" : 105, "y" : 1408 }, "to" : { "x" : 166, "y" : 1327 } }, { "from" : { "x" : 166, "y" : 1327 }, "to" : { "x" : 209, "y" : 1326 } } ], "stoichiometry" : { "value" : 1 } }, { "edgeId" : 25456, "type" : "CATALYST", "segments" : [ { "from" : { "x" : 98, "y" : 1408 }, "to" : { "x" : 100, "y" : 1279 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "c" : { "x" : 100, "y" : 1275 }, "r" : 4, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 100, "y" : 1275 } } } ] }, { "id" : 25451, "reactomeId" : 113550, "displayName" : "Pi", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 179, "y" : 1391 }, "minX" : 163, "maxX" : 204, "minY" : 1380, "maxY" : 1425, "prop" : { "x" : 163, "y" : 1381, "width" : 33, "height" : 20 }, "textPosition" : { "x" : 170, "y" : 1381 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 191, "y" : 1386 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 191, "y" : 1386 } } }, "connectors" : [ { "edgeId" : 25447, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 186, "y" : 1404 }, "to" : { "x" : 204, "y" : 1425 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 194, "y" : 1407 }, "b" : { "x" : 186, "y" : 1404 }, "c" : { "x" : 187, "y" : 1412 }, "type" : "ARROW", "centre" : { "x" : 187, "y" : 1412 } } } ] }, { "id" : 25452, "reactomeId" : 10396031, "displayName" : "CTDNEP1:CNEP1R1", "schemaClass" : "Complex", "renderableClass" : "Complex", "position" : { "x" : 234, "y" : 1482 }, "minX" : 171, "maxX" : 304, "minY" : 1435, "maxY" : 1493, "prop" : { "x" : 171, "y" : 1471, "width" : 127, "height" : 22 }, "textPosition" : { "x" : 171, "y" : 1472 }, "bgColor" : { "r" : 204, "g" : 255, "b" : 255 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 298, "y" : 1471 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 298, "y" : 1471 } } }, "connectors" : [ { "edgeId" : 25447, "type" : "CATALYST", "segments" : [ { "from" : { "x" : 233, "y" : 1468 }, "to" : { "x" : 232, "y" : 1443 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "c" : { "x" : 232, "y" : 1439 }, "r" : 4, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 232, "y" : 1439 } } } ] }, { "id" : 25454, "reactomeId" : 29358, "displayName" : "ATP", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 189, "y" : 1355 }, "minX" : 170, "maxX" : 209, "minY" : 1326, "maxY" : 1368, "prop" : { "x" : 170, "y" : 1342, "width" : 38, "height" : 26 }, "textPosition" : { "x" : 173, "y" : 1344 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 203, "y" : 1347 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 203, "y" : 1347 } } }, "connectors" : [ { "edgeId" : 25453, "type" : "INPUT", "segments" : [ { "from" : { "x" : 197, "y" : 1339 }, "to" : { "x" : 209, "y" : 1326 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 25455, "reactomeId" : 113582, "displayName" : "ADP", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 263, "y" : 1360 }, "minX" : 243, "maxX" : 285, "minY" : 1328, "maxY" : 1373, "prop" : { "x" : 243, "y" : 1347, "width" : 41, "height" : 26 }, "textPosition" : { "x" : 247, "y" : 1349 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 279, "y" : 1352 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 279, "y" : 1352 } } }, "connectors" : [ { "edgeId" : 25453, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 271, "y" : 1344 }, "to" : { "x" : 285, "y" : 1328 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 273, "y" : 1336 }, "b" : { "x" : 271, "y" : 1344 }, "c" : { "x" : 279, "y" : 1341 }, "type" : "ARROW", "centre" : { "x" : 279, "y" : 1341 } } } ] }, { "id" : 25457, "reactomeId" : 113518, "displayName" : "H2O", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 199, "y" : 1246 }, "minX" : 133, "maxX" : 222, "minY" : 1233, "maxY" : 1259, "prop" : { "x" : 177, "y" : 1234, "width" : 44, "height" : 25 }, "textPosition" : { "x" : 182, "y" : 1236 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 216, "y" : 1239 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 216, "y" : 1239 } } }, "connectors" : [ { "edgeId" : 25456, "type" : "INPUT", "segments" : [ { "from" : { "x" : 174, "y" : 1249 }, "to" : { "x" : 133, "y" : 1257 } } ], "stoichiometry" : { "value" : 1 } } ], "trivial" : true }, { "id" : 25458, "reactomeId" : 5221122, "displayName" : "1,2-diacyl-glycerol 3-phosphate", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 175, "y" : 1291 }, "minX" : 107, "maxX" : 245, "minY" : 1257, "maxY" : 1310, "prop" : { "x" : 107, "y" : 1273, "width" : 137, "height" : 37 }, "textPosition" : { "x" : 108, "y" : 1274 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 239, "y" : 1278 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 239, "y" : 1278 } } }, "connectors" : [ { "edgeId" : 25456, "type" : "INPUT", "segments" : [ { "from" : { "x" : 152, "y" : 1270 }, "to" : { "x" : 133, "y" : 1257 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 25459, "reactomeId" : 5221124, "displayName" : "DAG", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 70, "y" : 1202 }, "minX" : 49, "maxX" : 126, "minY" : 1175, "maxY" : 1238, "prop" : { "x" : 49, "y" : 1192, "width" : 42, "height" : 21 }, "textPosition" : { "x" : 53, "y" : 1192 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 86, "y" : 1197 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 86, "y" : 1197 } } }, "connectors" : [ { "edgeId" : 25456, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 78, "y" : 1216 }, "to" : { "x" : 99, "y" : 1238 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 86, "y" : 1218 }, "b" : { "x" : 78, "y" : 1216 }, "c" : { "x" : 80, "y" : 1224 }, "type" : "ARROW", "centre" : { "x" : 80, "y" : 1224 } } }, { "edgeId" : 25461, "type" : "INPUT", "segments" : [ { "from" : { "x" : 91, "y" : 1189 }, "to" : { "x" : 126, "y" : 1175 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 25460, "reactomeId" : 113550, "displayName" : "Pi", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 196, "y" : 1216 }, "minX" : 99, "maxX" : 214, "minY" : 1205, "maxY" : 1238, "prop" : { "x" : 180, "y" : 1206, "width" : 33, "height" : 20 }, "textPosition" : { "x" : 187, "y" : 1206 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 208, "y" : 1211 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 208, "y" : 1211 } } }, "connectors" : [ { "edgeId" : 25456, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 177, "y" : 1215 }, "to" : { "x" : 155, "y" : 1215 } }, { "from" : { "x" : 155, "y" : 1215 }, "to" : { "x" : 99, "y" : 1238 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 170, "y" : 1219 }, "b" : { "x" : 177, "y" : 1215 }, "c" : { "x" : 170, "y" : 1211 }, "type" : "ARROW", "centre" : { "x" : 170, "y" : 1211 } } } ] }, { "id" : 25462, "reactomeId" : 10398222, "displayName" : "phospho-p-T500,T642,S661-PRKCB", "schemaClass" : "EntityWithAccessionedSequence", "renderableClass" : "Protein", "position" : { "x" : 189, "y" : 1177 }, "minX" : 126, "maxX" : 225, "minY" : 1155, "maxY" : 1194, "prop" : { "x" : 160, "y" : 1161, "width" : 59, "height" : 33 }, "textPosition" : { "x" : 162, "y" : 1132 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 219, "y" : 1161 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 219, "y" : 1161 } } }, "connectors" : [ { "edgeId" : 25461, "type" : "INPUT", "segments" : [ { "from" : { "x" : 154, "y" : 1176 }, "to" : { "x" : 126, "y" : 1175 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 25463, "reactomeId" : 29496, "displayName" : "Ca2+", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 182, "y" : 1127 }, "minX" : 126, "maxX" : 208, "minY" : 1111, "maxY" : 1175, "prop" : { "x" : 157, "y" : 1112, "width" : 50, "height" : 30 }, "textPosition" : { "x" : 161, "y" : 1116 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 202, "y" : 1117 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 202, "y" : 1117 } } }, "connectors" : [ { "edgeId" : 25461, "type" : "INPUT", "segments" : [ { "from" : { "x" : 164, "y" : 1145 }, "to" : { "x" : 126, "y" : 1175 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 25464, "reactomeId" : 10398224, "displayName" : "DAG:active PKC:Ca+2", "schemaClass" : "Complex", "renderableClass" : "Complex", "position" : { "x" : 127, "y" : 1086 }, "minX" : 60, "maxX" : 185, "minY" : 973, "maxY" : 1104, "prop" : { "x" : 76, "y" : 1068, "width" : 103, "height" : 36 }, "textPosition" : { "x" : 88, "y" : 1069 }, "bgColor" : { "r" : 204, "g" : 255, "b" : 255 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 179, "y" : 1068 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 179, "y" : 1068 } } }, "connectors" : [ { "edgeId" : 25461, "type" : "OUTPUT", "segments" : [ ], "stoichiometry" : { "value" : 1 } }, { "edgeId" : 25465, "type" : "CATALYST", "segments" : [ { "from" : { "x" : 73, "y" : 1076 }, "to" : { "x" : 60, "y" : 1074 } }, { "from" : { "x" : 60, "y" : 1074 }, "to" : { "x" : 62, "y" : 979 } }, { "from" : { "x" : 62, "y" : 979 }, "to" : { "x" : 122, "y" : 977 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "c" : { "x" : 126, "y" : 977 }, "r" : 4, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 126, "y" : 977 } } } ] }, { "id" : 25466, "reactomeId" : 29358, "displayName" : "ATP", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 175, "y" : 953 }, "minX" : 139, "maxX" : 197, "minY" : 940, "maxY" : 966, "prop" : { "x" : 155, "y" : 941, "width" : 41, "height" : 25 }, "textPosition" : { "x" : 160, "y" : 943 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 191, "y" : 946 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 191, "y" : 946 } } }, "connectors" : [ { "edgeId" : 25465, "type" : "INPUT", "segments" : [ { "from" : { "x" : 152, "y" : 957 }, "to" : { "x" : 139, "y" : 961 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 25467, "reactomeId" : 113582, "displayName" : "ADP", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 181, "y" : 987 }, "minX" : 137, "maxX" : 204, "minY" : 975, "maxY" : 999, "prop" : { "x" : 160, "y" : 976, "width" : 43, "height" : 23 }, "textPosition" : { "x" : 165, "y" : 977 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 198, "y" : 981 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 198, "y" : 981 } } }, "connectors" : [ { "edgeId" : 25465, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 157, "y" : 989 }, "to" : { "x" : 137, "y" : 992 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 151, "y" : 994 }, "b" : { "x" : 157, "y" : 989 }, "c" : { "x" : 150, "y" : 986 }, "type" : "ARROW", "centre" : { "x" : 150, "y" : 986 } } } ] }, { "id" : 25468, "reactomeId" : 10398396, "displayName" : "p-S395-Lamin dimers", "schemaClass" : "CandidateSet", "renderableClass" : "EntitySet", "position" : { "x" : 281, "y" : 1184 }, "minX" : 137, "maxX" : 351, "minY" : 992, "maxY" : 1202, "prop" : { "x" : 232, "y" : 1166, "width" : 99, "height" : 36 }, "textPosition" : { "x" : 233, "y" : 1166 }, "connectors" : [ { "edgeId" : 25465, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 271, "y" : 1160 }, "to" : { "x" : 191, "y" : 1008 } }, { "from" : { "x" : 191, "y" : 1008 }, "to" : { "x" : 137, "y" : 992 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 264, "y" : 1156 }, "b" : { "x" : 271, "y" : 1160 }, "c" : { "x" : 271, "y" : 1152 }, "type" : "ARROW", "centre" : { "x" : 271, "y" : 1152 } } }, { "edgeId" : 25470, "type" : "INPUT", "segments" : [ { "from" : { "x" : 337, "y" : 1183 }, "to" : { "x" : 351, "y" : 1183 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 25469, "reactomeId" : 10391065, "displayName" : "EMD/ TMPO/ LEMD3/ LEMD2", "schemaClass" : "CandidateSet", "renderableClass" : "EntitySet", "position" : { "x" : 132, "y" : 1031 }, "minX" : 83, "maxX" : 182, "minY" : 992, "maxY" : 1049, "prop" : { "x" : 83, "y" : 1013, "width" : 99, "height" : 36 }, "textPosition" : { "x" : 83, "y" : 1013 }, "connectors" : [ { "edgeId" : 25465, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 134, "y" : 1007 }, "to" : { "x" : 137, "y" : 992 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 131, "y" : 999 }, "b" : { "x" : 134, "y" : 1007 }, "c" : { "x" : 139, "y" : 1001 }, "type" : "ARROW", "centre" : { "x" : 139, "y" : 1001 } } } ] }, { "id" : 25471, "reactomeId" : 29358, "displayName" : "ATP", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 339, "y" : 1226 }, "minX" : 318, "maxX" : 362, "minY" : 1183, "maxY" : 1237, "prop" : { "x" : 318, "y" : 1215, "width" : 43, "height" : 22 }, "textPosition" : { "x" : 324, "y" : 1215 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 356, "y" : 1220 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 356, "y" : 1220 } } }, "connectors" : [ { "edgeId" : 25470, "type" : "INPUT", "segments" : [ { "from" : { "x" : 342, "y" : 1212 }, "to" : { "x" : 351, "y" : 1183 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 25472, "reactomeId" : 113582, "displayName" : "ADP", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 401, "y" : 1224 }, "minX" : 379, "maxX" : 424, "minY" : 1183, "maxY" : 1235, "prop" : { "x" : 379, "y" : 1213, "width" : 44, "height" : 22 }, "textPosition" : { "x" : 384, "y" : 1213 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 418, "y" : 1218 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 418, "y" : 1218 } } }, "connectors" : [ { "edgeId" : 25470, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 398, "y" : 1210 }, "to" : { "x" : 390, "y" : 1183 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 392, "y" : 1204 }, "b" : { "x" : 398, "y" : 1210 }, "c" : { "x" : 400, "y" : 1202 }, "type" : "ARROW", "centre" : { "x" : 400, "y" : 1202 } } } ] }, { "id" : 25473, "reactomeId" : 10398540, "displayName" : "p-S22/23, S395-Lamin dimers", "schemaClass" : "CandidateSet", "renderableClass" : "EntitySet", "position" : { "x" : 469, "y" : 1182 }, "minX" : 390, "maxX" : 525, "minY" : 1162, "maxY" : 1202, "prop" : { "x" : 413, "y" : 1162, "width" : 112, "height" : 40 }, "textPosition" : { "x" : 415, "y" : 1164 }, "connectors" : [ { "edgeId" : 25470, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 407, "y" : 1182 }, "to" : { "x" : 390, "y" : 1183 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 400, "y" : 1186 }, "b" : { "x" : 407, "y" : 1182 }, "c" : { "x" : 400, "y" : 1178 }, "type" : "ARROW", "centre" : { "x" : 400, "y" : 1178 } } } ] }, { "id" : 25475, "reactomeId" : 29358, "displayName" : "ATP", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 805, "y" : 1281 }, "minX" : 785, "maxX" : 826, "minY" : 1222, "maxY" : 1293, "prop" : { "x" : 785, "y" : 1269, "width" : 40, "height" : 24 }, "textPosition" : { "x" : 789, "y" : 1270 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 820, "y" : 1274 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 820, "y" : 1274 } } }, "connectors" : [ { "edgeId" : 25474, "type" : "INPUT", "segments" : [ { "from" : { "x" : 808, "y" : 1266 }, "to" : { "x" : 822, "y" : 1222 } } ], "stoichiometry" : { "value" : 2, "shape" : { "a" : { "x" : 809, "y" : 1238 }, "b" : { "x" : 821, "y" : 1250 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 815, "y" : 1244 } } } } ] }, { "id" : 25476, "reactomeId" : 10359253, "displayName" : "NUMA1 homodimer", "schemaClass" : "Complex", "renderableClass" : "Complex", "position" : { "x" : 754, "y" : 1224 }, "minX" : 709, "maxX" : 822, "minY" : 1201, "maxY" : 1242, "prop" : { "x" : 709, "y" : 1207, "width" : 90, "height" : 35 }, "textPosition" : { "x" : 715, "y" : 1207 }, "bgColor" : { "r" : 204, "g" : 255, "b" : 255 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 799, "y" : 1207 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 799, "y" : 1207 } } }, "connectors" : [ { "edgeId" : 25474, "type" : "INPUT", "segments" : [ { "from" : { "x" : 802, "y" : 1222 }, "to" : { "x" : 822, "y" : 1222 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 25477, "reactomeId" : 10359258, "displayName" : "p-T2055-NUMA1 homodimer", "schemaClass" : "Complex", "renderableClass" : "Complex", "position" : { "x" : 992, "y" : 1222 }, "minX" : 885, "maxX" : 1057, "minY" : 1198, "maxY" : 1240, "prop" : { "x" : 933, "y" : 1204, "width" : 118, "height" : 36 }, "textPosition" : { "x" : 936, "y" : 1205 }, "bgColor" : { "r" : 204, "g" : 255, "b" : 255 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1051, "y" : 1204 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1051, "y" : 1204 } } }, "connectors" : [ { "edgeId" : 25474, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 930, "y" : 1222 }, "to" : { "x" : 885, "y" : 1222 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 923, "y" : 1226 }, "b" : { "x" : 930, "y" : 1222 }, "c" : { "x" : 923, "y" : 1218 }, "type" : "ARROW", "centre" : { "x" : 923, "y" : 1218 } } } ] }, { "id" : 25478, "reactomeId" : 113582, "displayName" : "ADP", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 918, "y" : 1276 }, "minX" : 885, "maxX" : 939, "minY" : 1222, "maxY" : 1288, "prop" : { "x" : 899, "y" : 1265, "width" : 39, "height" : 23 }, "textPosition" : { "x" : 902, "y" : 1266 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 933, "y" : 1270 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 933, "y" : 1270 } } }, "connectors" : [ { "edgeId" : 25474, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 910, "y" : 1262 }, "to" : { "x" : 885, "y" : 1222 } } ], "stoichiometry" : { "value" : 2, "shape" : { "a" : { "x" : 891, "y" : 1236 }, "b" : { "x" : 903, "y" : 1248 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 897, "y" : 1242 } } }, "endShape" : { "a" : { "x" : 903, "y" : 1258 }, "b" : { "x" : 910, "y" : 1262 }, "c" : { "x" : 910, "y" : 1254 }, "type" : "ARROW", "centre" : { "x" : 910, "y" : 1254 } } } ] }, { "id" : 25489, "reactomeId" : 10443492, "displayName" : "Mitotic G2-G2/M phases", "schemaClass" : "Pathway", "renderableClass" : "EncapsulatedNode", "position" : { "x" : 587, "y" : 1352 }, "minX" : 496, "maxX" : 678, "minY" : 1330, "maxY" : 1375, "prop" : { "x" : 496, "y" : 1330, "width" : 182, "height" : 45 }, "textPosition" : { "x" : 505, "y" : 1338 }, "connectors" : [ ] }, { "id" : 25490, "reactomeId" : 10443496, "displayName" : "Mitotic Prometaphase", "schemaClass" : "Pathway", "renderableClass" : "EncapsulatedNode", "position" : { "x" : 1676, "y" : 1101 }, "minX" : 1614, "maxX" : 1739, "minY" : 1075, "maxY" : 1128, "prop" : { "x" : 1614, "y" : 1075, "width" : 125, "height" : 53 }, "textPosition" : { "x" : 1622, "y" : 1080 }, "connectors" : [ ] } ], "edges" : [ { "id" : 25474, "reactomeId" : 10359260, "displayName" : "CCNB1:p-T160-CDK1 phosphorylates NUMA1", "schemaClass" : "Reaction", "renderableClass" : "Reaction", "position" : { "x" : 852, "y" : 1220 }, "minX" : 822, "maxX" : 885, "minY" : 1214, "maxY" : 1226, "reactionType" : "transition", "segments" : [ { "from" : { "x" : 822, "y" : 1222 }, "to" : { "x" : 852, "y" : 1220 } }, { "from" : { "x" : 852, "y" : 1220 }, "to" : { "x" : 885, "y" : 1222 } } ], "reactionShape" : { "a" : { "x" : 846, "y" : 1214 }, "b" : { "x" : 858, "y" : 1226 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 852, "y" : 1220 } }, "inputs" : [ { "id" : 25475, "points" : [ { "x" : 808, "y" : 1266 } ], "stoichiometry" : 2 }, { "id" : 25476, "points" : [ { "x" : 802, "y" : 1222 } ] } ], "outputs" : [ { "id" : 25477, "points" : [ { "x" : 930, "y" : 1222 } ] }, { "id" : 25478, "points" : [ { "x" : 910, "y" : 1262 } ], "stoichiometry" : 2 } ], "catalysts" : [ { "id" : 25372, "points" : [ { "x" : 703, "y" : 979 } ] } ] }, { "id" : 25410, "reactomeId" : 10390864, "displayName" : "CDK1:CCNB phosphorylates NEK9", "schemaClass" : "Reaction", "renderableClass" : "Reaction", "position" : { "x" : 317, "y" : 506 }, "minX" : 263, "maxX" : 375, "minY" : 500, "maxY" : 512, "reactionType" : "transition", "segments" : [ { "from" : { "x" : 263, "y" : 507 }, "to" : { "x" : 317, "y" : 506 } }, { "from" : { "x" : 317, "y" : 506 }, "to" : { "x" : 375, "y" : 506 } } ], "reactionShape" : { "a" : { "x" : 311, "y" : 500 }, "b" : { "x" : 323, "y" : 512 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 317, "y" : 506 } }, "inputs" : [ { "id" : 25411, "points" : [ { "x" : 230, "y" : 507 } ] }, { "id" : 25412, "points" : [ { "x" : 246, "y" : 456 } ], "stoichiometry" : 6 } ], "outputs" : [ { "id" : 25413, "points" : [ { "x" : 486, "y" : 505 } ] }, { "id" : 25414, "points" : [ { "x" : 395, "y" : 473 } ], "stoichiometry" : 6 } ], "catalysts" : [ { "id" : 25415, "points" : [ { "x" : 317, "y" : 355 } ] } ] }, { "id" : 25349, "reactomeId" : 10387416, "displayName" : "MASTL (GWL) phosphorylates ARPP19", "schemaClass" : "Reaction", "renderableClass" : "Reaction", "position" : { "x" : 1125, "y" : 1012 }, "minX" : 1104, "maxX" : 1142, "minY" : 1006, "maxY" : 1018, "reactionType" : "transition", "segments" : [ { "from" : { "x" : 1104, "y" : 1012 }, "to" : { "x" : 1125, "y" : 1012 } }, { "from" : { "x" : 1125, "y" : 1012 }, "to" : { "x" : 1142, "y" : 1013 } } ], "reactionShape" : { "a" : { "x" : 1119, "y" : 1006 }, "b" : { "x" : 1131, "y" : 1018 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 1125, "y" : 1012 } }, "inputs" : [ { "id" : 25350, "points" : [ { "x" : 1081, "y" : 1014 } ] }, { "id" : 25351, "points" : [ { "x" : 1104, "y" : 988 } ] } ], "outputs" : [ { "id" : 25352, "points" : [ { "x" : 1170, "y" : 994 } ] }, { "id" : 25353, "points" : [ { "x" : 1183, "y" : 1023 } ] } ], "catalysts" : [ { "id" : 25354, "points" : [ { "x" : 1101, "y" : 1053 }, { "x" : 1133, "y" : 1053 } ] } ] }, { "id" : 25416, "reactomeId" : 10390866, "displayName" : "PLK1 phosphorylates NEK9", "schemaClass" : "Reaction", "renderableClass" : "Reaction", "position" : { "x" : 826, "y" : 506 }, "minX" : 774, "maxX" : 877, "minY" : 500, "maxY" : 512, "reactionType" : "transition", "segments" : [ { "from" : { "x" : 774, "y" : 506 }, "to" : { "x" : 826, "y" : 506 } }, { "from" : { "x" : 826, "y" : 506 }, "to" : { "x" : 877, "y" : 505 } } ], "reactionShape" : { "a" : { "x" : 820, "y" : 500 }, "b" : { "x" : 832, "y" : 512 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 826, "y" : 506 } }, "inputs" : [ { "id" : 25413, "points" : [ { "x" : 589, "y" : 505 } ] }, { "id" : 25417, "points" : [ { "x" : 751, "y" : 468 } ], "stoichiometry" : 2 } ], "outputs" : [ { "id" : 25418, "points" : [ { "x" : 912, "y" : 504 } ] }, { "id" : 25419, "points" : [ { "x" : 902, "y" : 461 } ], "stoichiometry" : 2 } ], "catalysts" : [ { "id" : 25420, "points" : [ { "x" : 826, "y" : 406 } ] } ] }, { "id" : 25355, "reactomeId" : 10387635, "displayName" : "RB1 binds condensin II", "schemaClass" : "Reaction", "renderableClass" : "Reaction", "position" : { "x" : 649, "y" : 736 }, "minX" : 643, "maxX" : 655, "minY" : 730, "maxY" : 757, "reactionType" : "binding", "segments" : [ { "from" : { "x" : 648, "y" : 734 }, "to" : { "x" : 649, "y" : 736 } }, { "from" : { "x" : 649, "y" : 736 }, "to" : { "x" : 649, "y" : 757 } } ], "endShape" : { "a" : { "x" : 645, "y" : 750 }, "b" : { "x" : 649, "y" : 757 }, "c" : { "x" : 653, "y" : 750 }, "type" : "ARROW", "centre" : { "x" : 653, "y" : 750 } }, "reactionShape" : { "c" : { "x" : 649, "y" : 736 }, "r" : 5, "type" : "CIRCLE", "centre" : { "x" : 649, "y" : 736 } }, "inputs" : [ { "id" : 25356, "points" : [ { "x" : 682, "y" : 720 } ] }, { "id" : 25357, "points" : [ { "x" : 615, "y" : 716 } ] } ], "outputs" : [ { "id" : 25358 } ] }, { "id" : 25421, "reactomeId" : 10390844, "displayName" : "NEK9 binds NEK6/NEK7 in the cytosol", "schemaClass" : "Reaction", "renderableClass" : "Reaction", "position" : { "x" : 1055, "y" : 501 }, "minX" : 1049, "maxX" : 1081, "minY" : 495, "maxY" : 507, "reactionType" : "binding", "segments" : [ { "from" : { "x" : 1055, "y" : 500 }, "to" : { "x" : 1055, "y" : 501 } }, { "from" : { "x" : 1055, "y" : 501 }, "to" : { "x" : 1081, "y" : 500 } } ], "endShape" : { "a" : { "x" : 1074, "y" : 504 }, "b" : { "x" : 1081, "y" : 500 }, "c" : { "x" : 1074, "y" : 496 }, "type" : "ARROW", "centre" : { "x" : 1074, "y" : 496 } }, "reactionShape" : { "c" : { "x" : 1055, "y" : 501 }, "r" : 5, "type" : "CIRCLE", "centre" : { "x" : 1055, "y" : 501 } }, "inputs" : [ { "id" : 25422, "points" : [ { "x" : 1039, "y" : 471 } ] }, { "id" : 25418, "points" : [ { "x" : 1022, "y" : 501 } ] } ], "outputs" : [ { "id" : 25423 } ] }, { "id" : 25359, "reactomeId" : 10387675, "displayName" : "PHF8 demethylates histone H4K20me1", "schemaClass" : "Reaction", "renderableClass" : "Reaction", "position" : { "x" : 312, "y" : 1023 }, "minX" : 306, "maxX" : 318, "minY" : 997, "maxY" : 1059, "reactionType" : "transition", "segments" : [ { "from" : { "x" : 311, "y" : 997 }, "to" : { "x" : 312, "y" : 1023 } }, { "from" : { "x" : 312, "y" : 1023 }, "to" : { "x" : 314, "y" : 1059 } } ], "reactionShape" : { "a" : { "x" : 306, "y" : 1017 }, "b" : { "x" : 318, "y" : 1029 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 312, "y" : 1023 } }, "inputs" : [ { "id" : 25360, "points" : [ { "x" : 307, "y" : 966 } ] }, { "id" : 25361, "points" : [ { "x" : 284, "y" : 985 } ] }, { "id" : 25362, "points" : [ { "x" : 354, "y" : 921 } ] } ], "outputs" : [ { "id" : 25363, "points" : [ { "x" : 295, "y" : 1053 } ] }, { "id" : 25364, "points" : [ { "x" : 287, "y" : 1078 } ] }, { "id" : 25365, "points" : [ { "x" : 353, "y" : 1076 } ] }, { "id" : 25366, "points" : [ { "x" : 314, "y" : 1121 } ] } ], "catalysts" : [ { "id" : 25362, "points" : [ { "x" : 368, "y" : 921 }, { "x" : 368, "y" : 1021 } ] } ] }, { "id" : 25424, "reactomeId" : 10390879, "displayName" : "NEK9 phosphorylates NEK6/NEK7", "schemaClass" : "Reaction", "renderableClass" : "Reaction", "position" : { "x" : 1251, "y" : 498 }, "minX" : 1224, "maxX" : 1277, "minY" : 492, "maxY" : 504, "reactionType" : "transition", "segments" : [ { "from" : { "x" : 1224, "y" : 498 }, "to" : { "x" : 1251, "y" : 498 } }, { "from" : { "x" : 1251, "y" : 498 }, "to" : { "x" : 1277, "y" : 498 } } ], "reactionShape" : { "a" : { "x" : 1245, "y" : 492 }, "b" : { "x" : 1257, "y" : 504 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 1251, "y" : 498 } }, "inputs" : [ { "id" : 25423, "points" : [ { "x" : 1195, "y" : 498 } ] }, { "id" : 25425, "points" : [ { "x" : 1206, "y" : 440 } ] } ], "outputs" : [ { "id" : 25426, "points" : [ { "x" : 1311, "y" : 499 } ] }, { "id" : 25427, "points" : [ { "x" : 1305, "y" : 436 } ] } ], "catalysts" : [ { "id" : 25423, "points" : [ { "x" : 1195, "y" : 513 }, { "x" : 1234, "y" : 525 } ] } ] }, { "id" : 25428, "reactomeId" : 10390973, "displayName" : "CDK1 phosphorylates NUP98", "schemaClass" : "Reaction", "renderableClass" : "Reaction", "position" : { "x" : 382, "y" : 607 }, "minX" : 345, "maxX" : 439, "minY" : 601, "maxY" : 613, "reactionType" : "transition", "segments" : [ { "from" : { "x" : 345, "y" : 606 }, "to" : { "x" : 382, "y" : 607 } }, { "from" : { "x" : 382, "y" : 607 }, "to" : { "x" : 439, "y" : 606 } } ], "reactionShape" : { "a" : { "x" : 376, "y" : 601 }, "b" : { "x" : 388, "y" : 613 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 382, "y" : 607 } }, "inputs" : [ { "id" : 25429, "points" : [ { "x" : 319, "y" : 574 } ], "stoichiometry" : 40 }, { "id" : 25430, "points" : [ { "x" : 294, "y" : 606 } ] } ], "outputs" : [ { "id" : 25431, "points" : [ { "x" : 953, "y" : 604 } ] }, { "id" : 25432, "points" : [ { "x" : 459, "y" : 569 } ], "stoichiometry" : 40 } ], "catalysts" : [ { "id" : 25415, "points" : [ { "x" : 320, "y" : 355 } ] } ] }, { "id" : 25367, "reactomeId" : 10388287, "displayName" : "CDK1 phosphorylates PHF8", "schemaClass" : "Reaction", "renderableClass" : "Reaction", "position" : { "x" : 478, "y" : 898 }, "minX" : 460, "maxX" : 494, "minY" : 892, "maxY" : 904, "reactionType" : "transition", "segments" : [ { "from" : { "x" : 460, "y" : 898 }, "to" : { "x" : 478, "y" : 898 } }, { "from" : { "x" : 478, "y" : 898 }, "to" : { "x" : 494, "y" : 899 } } ], "reactionShape" : { "a" : { "x" : 472, "y" : 892 }, "b" : { "x" : 484, "y" : 904 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 478, "y" : 898 } }, "inputs" : [ { "id" : 25362, "points" : [ { "x" : 434, "y" : 896 } ] }, { "id" : 25368, "points" : [ { "x" : 449, "y" : 838 } ], "stoichiometry" : 2 } ], "outputs" : [ { "id" : 25369, "points" : [ { "x" : 520, "y" : 899 } ] }, { "id" : 25370, "points" : [ { "x" : 570, "y" : 837 } ] }, { "id" : 25371, "points" : [ { "x" : 504, "y" : 839 } ], "stoichiometry" : 2 } ], "catalysts" : [ { "id" : 25372, "points" : [ { "x" : 620, "y" : 963 }, { "x" : 477, "y" : 963 } ] } ] }, { "id" : 25433, "reactomeId" : 10390971, "displayName" : "NEK6/NEK7 phosphorylates NUP98", "schemaClass" : "Reaction", "renderableClass" : "Reaction", "position" : { "x" : 1370, "y" : 602 }, "minX" : 1277, "maxX" : 1434, "minY" : 596, "maxY" : 608, "reactionType" : "transition", "segments" : [ { "from" : { "x" : 1277, "y" : 601 }, "to" : { "x" : 1370, "y" : 602 } }, { "from" : { "x" : 1370, "y" : 602 }, "to" : { "x" : 1434, "y" : 603 } } ], "reactionShape" : { "a" : { "x" : 1364, "y" : 596 }, "b" : { "x" : 1376, "y" : 608 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 1370, "y" : 602 } }, "inputs" : [ { "id" : 25431, "points" : [ { "x" : 1102, "y" : 603 } ] }, { "id" : 25434, "points" : [ { "x" : 1261, "y" : 575 } ], "stoichiometry" : 16 } ], "outputs" : [ { "id" : 25435, "points" : [ { "x" : 1488, "y" : 556 } ], "stoichiometry" : 16 }, { "id" : 25436, "points" : [ { "x" : 1479, "y" : 659 } ], "stoichiometry" : 4 }, { "id" : 25437, "points" : [ { "x" : 1479, "y" : 601 } ] }, { "id" : 25438, "points" : [ { "x" : 1480, "y" : 479 } ], "stoichiometry" : 4 } ], "catalysts" : [ { "id" : 25426, "points" : [ { "x" : 1370, "y" : 529 } ] } ] }, { "id" : 25373, "reactomeId" : 10388341, "displayName" : "Condensin II complex binds H4K20me1-containing nucleosomes", "schemaClass" : "Reaction", "renderableClass" : "Reaction", "position" : { "x" : 720, "y" : 900 }, "minX" : 693, "maxX" : 742, "minY" : 895, "maxY" : 907, "reactionType" : "binding", "segments" : [ { "from" : { "x" : 699, "y" : 901 }, "to" : { "x" : 720, "y" : 900 } }, { "from" : { "x" : 720, "y" : 900 }, "to" : { "x" : 742, "y" : 900 } } ], "endShape" : { "a" : { "x" : 735, "y" : 904 }, "b" : { "x" : 742, "y" : 900 }, "c" : { "x" : 735, "y" : 896 }, "type" : "ARROW", "centre" : { "x" : 735, "y" : 896 } }, "reactionShape" : { "c" : { "x" : 720, "y" : 900 }, "r" : 5, "type" : "CIRCLE", "centre" : { "x" : 720, "y" : 900 } }, "inputs" : [ { "id" : 25369, "points" : [ { "x" : 645, "y" : 901 } ] }, { "id" : 25356, "points" : [ { "x" : 703, "y" : 720 } ] } ], "outputs" : [ { "id" : 25374 } ], "activators" : [ { "id" : 25358, "points" : [ { "x" : 656, "y" : 796 } ] } ] }, { "id" : 25375, "reactomeId" : 10388371, "displayName" : "CDK1 phosphorylates condensin II subunit NCAPD3", "schemaClass" : "Reaction", "renderableClass" : "Reaction", "position" : { "x" : 915, "y" : 899 }, "minX" : 887, "maxX" : 935, "minY" : 893, "maxY" : 905, "reactionType" : "transition", "segments" : [ { "from" : { "x" : 887, "y" : 898 }, "to" : { "x" : 915, "y" : 899 } }, { "from" : { "x" : 915, "y" : 899 }, "to" : { "x" : 935, "y" : 899 } } ], "reactionShape" : { "a" : { "x" : 909, "y" : 893 }, "b" : { "x" : 921, "y" : 905 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 915, "y" : 899 } }, "inputs" : [ { "id" : 25374, "points" : [ { "x" : 857, "y" : 898 } ] }, { "id" : 25376, "points" : [ { "x" : 869, "y" : 864 } ] } ], "outputs" : [ { "id" : 25377, "points" : [ { "x" : 945, "y" : 861 } ] }, { "id" : 25378, "points" : [ { "x" : 963, "y" : 899 } ] } ], "catalysts" : [ { "id" : 25372, "points" : [ { "x" : 772, "y" : 963 }, { "x" : 915, "y" : 963 } ] } ] }, { "id" : 25439, "reactomeId" : 10391107, "displayName" : "VRK1/VRK2 phosphorylate BANF1", "schemaClass" : "Reaction", "renderableClass" : "Reaction", "position" : { "x" : 149, "y" : 775 }, "minX" : 143, "maxX" : 155, "minY" : 741, "maxY" : 846, "reactionType" : "transition", "segments" : [ { "from" : { "x" : 148, "y" : 741 }, "to" : { "x" : 149, "y" : 775 } }, { "from" : { "x" : 149, "y" : 775 }, "to" : { "x" : 150, "y" : 846 } } ], "reactionShape" : { "a" : { "x" : 143, "y" : 769 }, "b" : { "x" : 155, "y" : 781 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 149, "y" : 775 } }, "inputs" : [ { "id" : 25440, "points" : [ { "x" : 184, "y" : 733 } ], "stoichiometry" : 6 }, { "id" : 25441, "points" : [ { "x" : 149, "y" : 707 } ] } ], "outputs" : [ { "id" : 25442, "points" : [ { "x" : 199, "y" : 863 } ], "stoichiometry" : 6 }, { "id" : 25443, "points" : [ { "x" : 143, "y" : 882 } ] }, { "id" : 25444, "points" : [ { "x" : 222, "y" : 823 } ] }, { "id" : 25445, "points" : [ { "x" : 249, "y" : 844 } ] } ], "catalysts" : [ { "id" : 25446, "points" : [ { "x" : 227, "y" : 772 } ] } ] }, { "id" : 25379, "reactomeId" : 10388369, "displayName" : "PLK1 binds phosphorylated condensin II complex", "schemaClass" : "Reaction", "renderableClass" : "Reaction", "position" : { "x" : 1129, "y" : 896 }, "minX" : 1112, "maxX" : 1152, "minY" : 890, "maxY" : 902, "reactionType" : "binding", "segments" : [ { "from" : { "x" : 1112, "y" : 896 }, "to" : { "x" : 1129, "y" : 896 } }, { "from" : { "x" : 1129, "y" : 896 }, "to" : { "x" : 1146, "y" : 896 } } ], "endShape" : { "a" : { "x" : 1139, "y" : 900 }, "b" : { "x" : 1146, "y" : 896 }, "c" : { "x" : 1139, "y" : 892 }, "type" : "ARROW", "centre" : { "x" : 1139, "y" : 892 } }, "reactionShape" : { "c" : { "x" : 1129, "y" : 896 }, "r" : 5, "type" : "CIRCLE", "centre" : { "x" : 1129, "y" : 896 } }, "inputs" : [ { "id" : 25380, "points" : [ { "x" : 1090, "y" : 825 } ] }, { "id" : 25378, "points" : [ { "x" : 1079, "y" : 897 } ] } ], "outputs" : [ { "id" : 25381 } ] }, { "id" : 25382, "reactomeId" : 10388365, "displayName" : "PLK1 hyperphosphorylates Condensin II complex", "schemaClass" : "Reaction", "renderableClass" : "Reaction", "position" : { "x" : 1302, "y" : 900 }, "minX" : 1281, "maxX" : 1320, "minY" : 894, "maxY" : 906, "reactionType" : "transition", "segments" : [ { "from" : { "x" : 1281, "y" : 899 }, "to" : { "x" : 1302, "y" : 900 } }, { "from" : { "x" : 1302, "y" : 900 }, "to" : { "x" : 1320, "y" : 900 } } ], "reactionShape" : { "a" : { "x" : 1296, "y" : 894 }, "b" : { "x" : 1308, "y" : 906 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 1302, "y" : 900 } }, "inputs" : [ { "id" : 25381, "points" : [ { "x" : 1255, "y" : 897 } ] }, { "id" : 25383, "points" : [ { "x" : 1269, "y" : 941 } ] } ], "outputs" : [ { "id" : 25384, "points" : [ { "x" : 1525, "y" : 893 } ] }, { "id" : 25385, "points" : [ { "x" : 1338, "y" : 947 } ] } ], "catalysts" : [ { "id" : 25381, "points" : [ { "x" : 1255, "y" : 878 }, { "x" : 1283, "y" : 868 } ] } ] }, { "id" : 25447, "reactomeId" : 10396034, "displayName" : "CTDNEP1:CNEP1R1 dephosphorylates LPIN", "schemaClass" : "Reaction", "renderableClass" : "Reaction", "position" : { "x" : 232, "y" : 1427 }, "minX" : 204, "maxX" : 256, "minY" : 1421, "maxY" : 1433, "reactionType" : "transition", "segments" : [ { "from" : { "x" : 256, "y" : 1425 }, "to" : { "x" : 232, "y" : 1427 } }, { "from" : { "x" : 232, "y" : 1427 }, "to" : { "x" : 204, "y" : 1425 } } ], "reactionShape" : { "a" : { "x" : 226, "y" : 1421 }, "b" : { "x" : 238, "y" : 1433 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 232, "y" : 1427 } }, "inputs" : [ { "id" : 25448, "points" : [ { "x" : 271, "y" : 1410 } ] }, { "id" : 25449, "points" : [ { "x" : 319, "y" : 1425 } ] } ], "outputs" : [ { "id" : 25450, "points" : [ { "x" : 121, "y" : 1425 } ] }, { "id" : 25451, "points" : [ { "x" : 186, "y" : 1404 } ] } ], "catalysts" : [ { "id" : 25452, "points" : [ { "x" : 233, "y" : 1468 } ] } ] }, { "id" : 25386, "reactomeId" : 10388382, "displayName" : "SETD8 monomethylates histone H4", "schemaClass" : "Reaction", "renderableClass" : "Reaction", "position" : { "x" : 393, "y" : 997 }, "minX" : 386, "maxX" : 399, "minY" : 951, "maxY" : 1052, "reactionType" : "transition", "segments" : [ { "from" : { "x" : 392, "y" : 1052 }, "to" : { "x" : 393, "y" : 997 } }, { "from" : { "x" : 393, "y" : 997 }, "to" : { "x" : 386, "y" : 951 } } ], "reactionShape" : { "a" : { "x" : 387, "y" : 991 }, "b" : { "x" : 399, "y" : 1003 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 393, "y" : 997 } }, "inputs" : [ { "id" : 25365, "points" : [ { "x" : 390, "y" : 1076 } ] }, { "id" : 25387, "points" : [ { "x" : 405, "y" : 1051 } ] } ], "outputs" : [ { "id" : 25388, "points" : [ { "x" : 403, "y" : 948 } ] }, { "id" : 25362, "points" : [ { "x" : 375, "y" : 921 } ] } ], "catalysts" : [ { "id" : 25389, "points" : [ { "x" : 420, "y" : 997 } ] } ] }, { "id" : 25453, "reactomeId" : 10397555, "displayName" : "CDK1 phosphorylates LPIN", "schemaClass" : "Reaction", "renderableClass" : "Reaction", "position" : { "x" : 241, "y" : 1325 }, "minX" : 209, "maxX" : 285, "minY" : 1319, "maxY" : 1331, "reactionType" : "transition", "segments" : [ { "from" : { "x" : 209, "y" : 1326 }, "to" : { "x" : 241, "y" : 1325 } }, { "from" : { "x" : 241, "y" : 1325 }, "to" : { "x" : 285, "y" : 1328 } } ], "reactionShape" : { "a" : { "x" : 235, "y" : 1319 }, "b" : { "x" : 247, "y" : 1331 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 241, "y" : 1325 } }, "inputs" : [ { "id" : 25450, "points" : [ { "x" : 105, "y" : 1408 }, { "x" : 166, "y" : 1327 } ] }, { "id" : 25454, "points" : [ { "x" : 197, "y" : 1339 } ] } ], "outputs" : [ { "id" : 25449, "points" : [ { "x" : 342, "y" : 1402 } ] }, { "id" : 25455, "points" : [ { "x" : 271, "y" : 1344 } ] } ], "catalysts" : [ { "id" : 25372, "points" : [ { "x" : 620, "y" : 968 }, { "x" : 584, "y" : 971 }, { "x" : 556, "y" : 1299 }, { "x" : 286, "y" : 1297 } ] } ] }, { "id" : 25390, "reactomeId" : 10388195, "displayName" : "PLK1 phosphorylates GORASP1", "schemaClass" : "Reaction", "renderableClass" : "Reaction", "position" : { "x" : 1010, "y" : 220 }, "minX" : 994, "maxX" : 1027, "minY" : 214, "maxY" : 226, "reactionType" : "transition", "segments" : [ { "from" : { "x" : 994, "y" : 221 }, "to" : { "x" : 1010, "y" : 220 } }, { "from" : { "x" : 1010, "y" : 220 }, "to" : { "x" : 1027, "y" : 221 } } ], "reactionShape" : { "a" : { "x" : 1004, "y" : 214 }, "b" : { "x" : 1016, "y" : 226 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 1010, "y" : 220 } }, "inputs" : [ { "id" : 25391, "points" : [ { "x" : 979, "y" : 297 } ] }, { "id" : 25392, "points" : [ { "x" : 974, "y" : 221 } ] } ], "outputs" : [ { "id" : 25393, "points" : [ { "x" : 1077, "y" : 218 } ] }, { "id" : 25394, "points" : [ { "x" : 1038, "y" : 294 } ] } ], "catalysts" : [ { "id" : 25392, "points" : [ { "x" : 974, "y" : 196 }, { "x" : 996, "y" : 187 } ] } ] }, { "id" : 25456, "reactomeId" : 10398220, "displayName" : "LPIN catalyzes conversion of phosphatidic acid to diacylglycerol", "schemaClass" : "Reaction", "renderableClass" : "Reaction", "position" : { "x" : 100, "y" : 1263 }, "minX" : 94, "maxX" : 133, "minY" : 1238, "maxY" : 1269, "reactionType" : "transition", "segments" : [ { "from" : { "x" : 133, "y" : 1257 }, "to" : { "x" : 100, "y" : 1263 } }, { "from" : { "x" : 100, "y" : 1263 }, "to" : { "x" : 99, "y" : 1238 } } ], "reactionShape" : { "a" : { "x" : 94, "y" : 1257 }, "b" : { "x" : 106, "y" : 1269 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 100, "y" : 1263 } }, "inputs" : [ { "id" : 25457, "points" : [ { "x" : 174, "y" : 1249 } ] }, { "id" : 25458, "points" : [ { "x" : 152, "y" : 1270 } ] } ], "outputs" : [ { "id" : 25459, "points" : [ { "x" : 78, "y" : 1216 } ] }, { "id" : 25460, "points" : [ { "x" : 177, "y" : 1215 }, { "x" : 155, "y" : 1215 } ] } ], "catalysts" : [ { "id" : 25450, "points" : [ { "x" : 98, "y" : 1408 } ] } ] }, { "id" : 25395, "reactomeId" : 10389031, "displayName" : "MAPK3-3 or MAPK1 phosphorylate GORASP2", "schemaClass" : "Reaction", "renderableClass" : "Reaction", "position" : { "x" : 677, "y" : 151 }, "minX" : 629, "maxX" : 730, "minY" : 145, "maxY" : 157, "reactionType" : "transition", "segments" : [ { "from" : { "x" : 629, "y" : 150 }, "to" : { "x" : 677, "y" : 151 } }, { "from" : { "x" : 677, "y" : 151 }, "to" : { "x" : 730, "y" : 151 } } ], "reactionShape" : { "a" : { "x" : 671, "y" : 145 }, "b" : { "x" : 683, "y" : 157 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 677, "y" : 151 } }, "inputs" : [ { "id" : 25396, "points" : [ { "x" : 603, "y" : 115 } ], "stoichiometry" : 2 }, { "id" : 25397, "points" : [ { "x" : 582, "y" : 149 } ] } ], "outputs" : [ { "id" : 25398, "points" : [ { "x" : 781, "y" : 151 } ] }, { "id" : 25399, "points" : [ { "x" : 742, "y" : 110 } ], "stoichiometry" : 2 } ], "catalysts" : [ { "id" : 25400, "points" : [ { "x" : 675, "y" : 71 } ] } ] }, { "id" : 25461, "reactomeId" : 10398226, "displayName" : "DAG and Ca+2 bind to PKC and tether it to membrane", "schemaClass" : "Reaction", "renderableClass" : "Reaction", "position" : { "x" : 128, "y" : 1175 }, "minX" : 122, "maxX" : 134, "minY" : 1107, "maxY" : 1181, "reactionType" : "binding", "segments" : [ { "from" : { "x" : 126, "y" : 1175 }, "to" : { "x" : 128, "y" : 1175 } }, { "from" : { "x" : 128, "y" : 1175 }, "to" : { "x" : 127, "y" : 1107 } } ], "endShape" : { "a" : { "x" : 131, "y" : 1114 }, "b" : { "x" : 127, "y" : 1107 }, "c" : { "x" : 123, "y" : 1114 }, "type" : "ARROW", "centre" : { "x" : 123, "y" : 1114 } }, "reactionShape" : { "c" : { "x" : 128, "y" : 1175 }, "r" : 5, "type" : "CIRCLE", "centre" : { "x" : 128, "y" : 1175 } }, "inputs" : [ { "id" : 25459, "points" : [ { "x" : 91, "y" : 1189 } ] }, { "id" : 25462, "points" : [ { "x" : 154, "y" : 1176 } ] }, { "id" : 25463, "points" : [ { "x" : 164, "y" : 1145 } ] } ], "outputs" : [ { "id" : 25464 } ] }, { "id" : 25401, "reactomeId" : 10389194, "displayName" : "MCPH1 sequesters condensin II", "schemaClass" : "Reaction", "renderableClass" : "Reaction", "position" : { "x" : 825, "y" : 707 }, "minX" : 819, "maxX" : 855, "minY" : 701, "maxY" : 713, "reactionType" : "binding", "segments" : [ { "from" : { "x" : 826, "y" : 706 }, "to" : { "x" : 825, "y" : 707 } }, { "from" : { "x" : 825, "y" : 707 }, "to" : { "x" : 855, "y" : 706 } } ], "endShape" : { "a" : { "x" : 848, "y" : 710 }, "b" : { "x" : 855, "y" : 706 }, "c" : { "x" : 848, "y" : 702 }, "type" : "ARROW", "centre" : { "x" : 848, "y" : 702 } }, "reactionShape" : { "c" : { "x" : 825, "y" : 707 }, "r" : 5, "type" : "CIRCLE", "centre" : { "x" : 825, "y" : 707 } }, "inputs" : [ { "id" : 25402, "points" : [ { "x" : 823, "y" : 657 } ] }, { "id" : 25356, "points" : [ { "x" : 758, "y" : 706 } ] }, { "id" : 25403, "points" : [ { "x" : 780, "y" : 677 } ] } ], "outputs" : [ { "id" : 25404 } ] }, { "id" : 25465, "reactomeId" : 10398399, "displayName" : "Depolymerization of lamin filaments after PKC-mediated phosphorylation", "schemaClass" : "Depolymerisation", "renderableClass" : "Reaction", "position" : { "x" : 138, "y" : 977 }, "minX" : 132, "maxX" : 144, "minY" : 961, "maxY" : 992, "reactionType" : "dissociation", "segments" : [ { "from" : { "x" : 139, "y" : 961 }, "to" : { "x" : 138, "y" : 977 } }, { "from" : { "x" : 138, "y" : 977 }, "to" : { "x" : 137, "y" : 992 } } ], "reactionShape" : { "c" : { "x" : 138, "y" : 977 }, "r" : 5, "r1" : 3, "type" : "DOUBLE_CIRCLE", "empty" : true, "centre" : { "x" : 138, "y" : 977 } }, "inputs" : [ { "id" : 25443, "points" : [ { "x" : 139, "y" : 936 } ] }, { "id" : 25466, "points" : [ { "x" : 152, "y" : 957 } ] } ], "outputs" : [ { "id" : 25467, "points" : [ { "x" : 157, "y" : 989 } ] }, { "id" : 25468, "points" : [ { "x" : 271, "y" : 1160 }, { "x" : 191, "y" : 1008 } ] }, { "id" : 25469, "points" : [ { "x" : 134, "y" : 1007 } ] } ], "catalysts" : [ { "id" : 25464, "points" : [ { "x" : 73, "y" : 1076 }, { "x" : 60, "y" : 1074 }, { "x" : 62, "y" : 979 } ] } ] }, { "id" : 25405, "reactomeId" : 10389203, "displayName" : "MASTL phosphorylates ENSA", "schemaClass" : "Reaction", "renderableClass" : "Reaction", "position" : { "x" : 1116, "y" : 1106 }, "minX" : 1093, "maxX" : 1138, "minY" : 1100, "maxY" : 1112, "reactionType" : "transition", "segments" : [ { "from" : { "x" : 1093, "y" : 1108 }, "to" : { "x" : 1116, "y" : 1106 } }, { "from" : { "x" : 1116, "y" : 1106 }, "to" : { "x" : 1138, "y" : 1106 } } ], "reactionShape" : { "a" : { "x" : 1110, "y" : 1100 }, "b" : { "x" : 1122, "y" : 1112 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 1116, "y" : 1106 } }, "inputs" : [ { "id" : 25406, "points" : [ { "x" : 1068, "y" : 1111 } ] }, { "id" : 25407, "points" : [ { "x" : 1086, "y" : 1136 } ] } ], "outputs" : [ { "id" : 25408, "points" : [ { "x" : 1154, "y" : 1133 } ] }, { "id" : 25409, "points" : [ { "x" : 1166, "y" : 1110 } ] } ], "catalysts" : [ { "id" : 25354, "points" : [ { "x" : 1063, "y" : 1073 }, { "x" : 1110, "y" : 1081 } ] } ] }, { "id" : 25470, "reactomeId" : 10398542, "displayName" : "CDK1 phosphorylates lamins and facilitates depolymerization of lamin filaments", "schemaClass" : "Reaction", "renderableClass" : "Reaction", "position" : { "x" : 369, "y" : 1183 }, "minX" : 351, "maxX" : 390, "minY" : 1177, "maxY" : 1189, "reactionType" : "transition", "segments" : [ { "from" : { "x" : 351, "y" : 1183 }, "to" : { "x" : 369, "y" : 1183 } }, { "from" : { "x" : 369, "y" : 1183 }, "to" : { "x" : 390, "y" : 1183 } } ], "reactionShape" : { "a" : { "x" : 363, "y" : 1177 }, "b" : { "x" : 375, "y" : 1189 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 369, "y" : 1183 } }, "inputs" : [ { "id" : 25468, "points" : [ { "x" : 337, "y" : 1183 } ] }, { "id" : 25471, "points" : [ { "x" : 342, "y" : 1212 } ] } ], "outputs" : [ { "id" : 25472, "points" : [ { "x" : 398, "y" : 1210 } ] }, { "id" : 25473, "points" : [ { "x" : 407, "y" : 1182 } ] } ], "catalysts" : [ { "id" : 25372, "points" : [ { "x" : 620, "y" : 966 }, { "x" : 520, "y" : 970 }, { "x" : 477, "y" : 1145 }, { "x" : 370, "y" : 1148 } ] } ] } ], "compartments" : [ { "id" : 25479, "reactomeId" : 70101, "displayName" : "cytosol", "schemaClass" : "Compartment", "renderableClass" : "Compartment", "position" : { "x" : 986, "y" : 786 }, "minX" : 0, "maxX" : 1972, "minY" : 0, "maxY" : 1572, "prop" : { "x" : 0, "y" : 0, "width" : 1972, "height" : 1572 }, "textPosition" : { "x" : 28, "y" : 1510 }, "insets" : { "x" : 10, "y" : 10, "width" : 1952, "height" : 1552 }, "bgColor" : { "r" : 250, "g" : 240, "b" : 240 }, "componentIds" : [ 25480, 25415, 25483, 25484, 25391, 25394, 25400, 25399, 25396, 25412, 25414, 25411, 25410, 25413, 25416, 25417, 25418, 25419, 25421, 25422, 25423, 25424, 25425, 25427, 25426, 25432, 25438, 25434, 25435, 25429, 25420 ] }, { "id" : 25480, "reactomeId" : 7660, "displayName" : "nucleoplasm", "schemaClass" : "Compartment", "renderableClass" : "Compartment", "position" : { "x" : 956, "y" : 1050 }, "minX" : 36, "maxX" : 1877, "minY" : 595, "maxY" : 1506, "prop" : { "x" : 36, "y" : 595, "width" : 1841, "height" : 911 }, "textPosition" : { "x" : 388, "y" : 1420 }, "insets" : { "x" : 46, "y" : 605, "width" : 1821, "height" : 891 }, "bgColor" : { "r" : 250, "g" : 240, "b" : 240 }, "componentIds" : [ 25350, 25349, 25353, 25355, 25356, 25357, 25358, 25360, 25361, 25362, 25363, 25364, 25365, 25366, 25359, 25367, 25368, 25369, 25370, 25371, 25372, 25373, 25374, 25375, 25376, 25377, 25378, 25379, 25381, 25384, 25385, 25382, 25383, 25386, 25387, 25388, 25389, 25401, 25402, 25403, 25404, 25354, 25406, 25405, 25409, 25491, 25492, 25351, 25352, 25407, 25408, 25489, 25493, 25430, 25428, 25431, 25433, 25437, 25436, 25441, 25443, 25445, 25446, 25439, 25444, 25440, 25442, 25490, 25494, 25447, 25449, 25450, 25451, 25452, 25448, 25453, 25454, 25455, 25456, 25458, 25457, 25459, 25461, 25463, 25464, 25462, 25465, 25466, 25467, 25468, 25469, 25470, 25471, 25472, 25473, 25460, 25380, 25474, 25476, 25477, 25478, 25475 ] }, { "id" : 25483, "reactomeId" : 20699, "displayName" : "Golgi membrane", "schemaClass" : "Compartment", "renderableClass" : "Compartment", "position" : { "x" : 740, "y" : 207 }, "minX" : 93, "maxX" : 1388, "minY" : 127, "maxY" : 287, "prop" : { "x" : 93, "y" : 127, "width" : 1295, "height" : 160 }, "textPosition" : { "x" : 111, "y" : 137 }, "bgColor" : { "r" : 250, "g" : 240, "b" : 240 }, "componentIds" : [ 25392, 25390, 25393, 25397, 25395, 25398 ] }, { "id" : 25484, "reactomeId" : 13945, "displayName" : "ER to Golgi transport vesicle membrane", "schemaClass" : "Compartment", "renderableClass" : "Compartment", "position" : { "x" : 568, "y" : 392 }, "minX" : 427, "maxX" : 710, "minY" : 350, "maxY" : 434, "prop" : { "x" : 427, "y" : 350, "width" : 283, "height" : 84 }, "textPosition" : { "x" : 430, "y" : 398 }, "bgColor" : { "r" : 250, "g" : 240, "b" : 240 } } ], "notes" : [ ], "links" : [ { "id" : 25493, "renderableClass" : "Interaction", "position" : { "x" : 595, "y" : 976 }, "minX" : 587, "maxX" : 620, "minY" : 970, "maxY" : 1327, "interactionType" : "Activate", "segments" : [ { "from" : { "x" : 587, "y" : 1327 }, "to" : { "x" : 595, "y" : 976 } }, { "from" : { "x" : 595, "y" : 976 }, "to" : { "x" : 620, "y" : 972 } } ], "endShape" : { "a" : { "x" : 614, "y" : 977 }, "b" : { "x" : 620, "y" : 972 }, "c" : { "x" : 613, "y" : 969 }, "type" : "ARROW", "empty" : true, "centre" : { "x" : 613, "y" : 969 } }, "reactionShape" : { "a" : { "x" : 589, "y" : 970 }, "b" : { "x" : 601, "y" : 982 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 595, "y" : 976 } }, "inputs" : [ { "id" : 25489 } ], "outputs" : [ { "id" : 25372 } ] } ], "shadows" : [ { "id" : 25494, "reactomeId" : 10445226, "displayName" : "MASTL Facilitates Mitotic Progression", "schemaClass" : "Pathway", "renderableClass" : "Shadow", "position" : { "x" : 1092, "y" : 1062 }, "minX" : 901, "maxX" : 1283, "minY" : 952, "maxY" : 1172, "prop" : { "x" : 901, "y" : 952, "width" : 382, "height" : 220 }, "points" : [ { "x" : 901, "y" : 952 }, { "x" : 1283, "y" : 952 }, { "x" : 1283, "y" : 1172 }, { "x" : 901, "y" : 1172 } ], "colour" : "#4684ee" }, { "id" : 25495, "reactomeId" : 10445232, "displayName" : "Condensation of Prophase Chromosomes", "schemaClass" : "Pathway", "renderableClass" : "Shadow", "position" : { "x" : 951, "y" : 891 }, "minX" : 231, "maxX" : 1672, "minY" : 625, "maxY" : 1158, "prop" : { "x" : 231, "y" : 625, "width" : 1441, "height" : 533 }, "points" : [ { "x" : 231, "y" : 625 }, { "x" : 1672, "y" : 625 }, { "x" : 1672, "y" : 1158 }, { "x" : 231, "y" : 1158 } ], "colour" : "#dc3912" }, { "id" : 25496, "reactomeId" : 10445242, "displayName" : "Golgi Cisternae Pericentriolar Stack Reorganization", "schemaClass" : "Pathway", "renderableClass" : "Shadow", "position" : { "x" : 813, "y" : 175 }, "minX" : 386, "maxX" : 1240, "minY" : 18, "maxY" : 333, "prop" : { "x" : 386, "y" : 18, "width" : 854, "height" : 288 }, "points" : [ { "x" : 386, "y" : 18 }, { "x" : 1240, "y" : 18 }, { "x" : 1240, "y" : 333 }, { "x" : 386, "y" : 333 } ], "colour" : "#008000" }, { "id" : 25497, "reactomeId" : 10445294, "displayName" : "Nuclear Envelope Breakdown", "schemaClass" : "Pathway", "renderableClass" : "Shadow", "position" : { "x" : 812, "y" : 904 }, "minX" : 39, "maxX" : 1586, "minY" : 306, "maxY" : 1503, "prop" : { "x" : 39, "y" : 1172, "width" : 1547, "height" : 331 }, "points" : [ { "x" : 39, "y" : 306 }, { "x" : 1586, "y" : 306 }, { "x" : 1586, "y" : 1503 }, { "x" : 39, "y" : 1503 } ], "colour" : "#666666" } ], "minX" : 0, "maxX" : 1972, "minY" : 0, "maxY" : 1572, "disease" : false }