{
  "dbId" : 10331925,
  "stId" : "R-CFA-9856649",
  "speciesName" : "Canis familiaris",
  "nodes" : [ {
    "dbId" : 10323998,
    "stId" : "R-CFA-9825686",
    "displayName" : "phospho-KARS1 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 49646,
    "identifier" : "A0A8I3PI46",
    "standardIdentifier" : "uniprot:A0A8I3PI46",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "KARS1" ],
    "parents" : [ 10324000 ],
    "children" : [ ]
  }, {
    "dbId" : 10323870,
    "stId" : "R-CFA-9824966",
    "displayName" : "phospho-MITF [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 49646,
    "diagramIds" : [ 25542 ],
    "identifier" : "A0A8I3N265",
    "standardIdentifier" : "uniprot:A0A8I3N265",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "MITF" ],
    "parents" : [ ],
    "children" : [ ]
  }, {
    "dbId" : 113541,
    "stId" : "R-ALL-113541",
    "displayName" : "PPi [nucleoplasm]",
    "schemaClass" : "SimpleEntity",
    "speciesId" : 0,
    "diagramIds" : [ 25561 ],
    "identifier" : "33019",
    "standardIdentifier" : "chebi:33019",
    "chebiIdentifier" : "chebi:33019",
    "referenceType" : "ReferenceMolecule",
    "parents" : [ ],
    "children" : [ ]
  }, {
    "dbId" : 10323993,
    "stId" : "R-CFA-379688",
    "displayName" : "aminoacyl-tRNA synthetase multienzyme complex [cytosol]",
    "schemaClass" : "Complex",
    "speciesId" : 49646,
    "diagramIds" : [ 25551 ],
    "parents" : [ ],
    "children" : [ 10323987, 10323971, 10323953, 10323991, 10323975, 10323957, 10323979, 10323961, 10323983, 10323965, 10323949 ]
  }, {
    "dbId" : 10323864,
    "stId" : "R-CFA-9824962",
    "displayName" : "phospho-MITF [nucleoplasm]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 49646,
    "diagramIds" : [ 25537 ],
    "identifier" : "A0A8I3N265",
    "standardIdentifier" : "uniprot:A0A8I3N265",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "MITF" ],
    "parents" : [ 10323866 ],
    "children" : [ ]
  }, {
    "dbId" : 427523,
    "stId" : "R-ALL-427523",
    "displayName" : "NAD+ [nucleoplasm]",
    "schemaClass" : "SimpleEntity",
    "speciesId" : 0,
    "diagramIds" : [ 25572 ],
    "identifier" : "57540",
    "standardIdentifier" : "chebi:57540",
    "referenceType" : "ReferenceMolecule",
    "parents" : [ ],
    "children" : [ ]
  }, {
    "dbId" : 10323995,
    "stId" : "R-CFA-9825709",
    "displayName" : "KARS-depleted MSC [cytosol]",
    "schemaClass" : "Complex",
    "speciesId" : 49646,
    "diagramIds" : [ 25554 ],
    "parents" : [ ],
    "children" : [ 10323987, 10323953, 10323991, 10323975, 10323957, 10323979, 10323961, 10323983, 10323965, 10323949 ]
  }, {
    "dbId" : 10323866,
    "stId" : "R-CFA-9824974",
    "displayName" : "p-S69,73 MITF-M:XPO1 [nucleoplasm]",
    "schemaClass" : "Complex",
    "speciesId" : 49646,
    "diagramIds" : [ 25539 ],
    "parents" : [ ],
    "children" : [ 10323864, 10238697 ]
  }, {
    "dbId" : 10235924,
    "stId" : "R-CFA-165539",
    "displayName" : "XPO1 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 49646,
    "diagramIds" : [ 25541 ],
    "identifier" : "A0A8I3NNH1",
    "standardIdentifier" : "uniprot:A0A8I3NNH1",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "XPO1" ],
    "parents" : [ ],
    "children" : [ ]
  }, {
    "dbId" : 10323991,
    "stId" : "R-CFA-379586",
    "displayName" : "RARS1 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 49646,
    "identifier" : "A0A8I3RSP3",
    "standardIdentifier" : "uniprot:A0A8I3RSP3",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "RARS1" ],
    "parents" : [ 10323995, 10323993 ],
    "children" : [ ]
  }, {
    "dbId" : 10265360,
    "stId" : "R-CFA-1027362",
    "displayName" : "CREBBP,EP300 [nucleoplasm]",
    "schemaClass" : "DefinedSet",
    "speciesId" : 49646,
    "diagramIds" : [ 25594 ],
    "parents" : [ 10326657 ],
    "children" : [ 10254003, 10265358 ]
  }, {
    "dbId" : 10323987,
    "stId" : "R-CFA-379609",
    "displayName" : "AIMP1 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 49646,
    "identifier" : "A0A8I3Q1I7",
    "standardIdentifier" : "uniprot:A0A8I3Q1I7",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "AIMP1" ],
    "parents" : [ 10323995, 10323993 ],
    "children" : [ ]
  }, {
    "dbId" : 10323858,
    "stId" : "R-CFA-9824575",
    "displayName" : "phospho-MITF [nucleoplasm]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 49646,
    "diagramIds" : [ 25521 ],
    "identifier" : "A0A8I3N265",
    "standardIdentifier" : "uniprot:A0A8I3N265",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "MITF" ],
    "parents" : [ ],
    "children" : [ ]
  }, {
    "dbId" : 10246668,
    "stId" : "R-CFA-1433307",
    "displayName" : "sSCF dimer [extracellular region]",
    "schemaClass" : "Complex",
    "speciesId" : 49646,
    "parents" : [ 10246691 ],
    "children" : [ 10246666 ]
  }, {
    "dbId" : 10323855,
    "stId" : "R-CFA-9824664",
    "displayName" : "MITF [nucleoplasm]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 49646,
    "diagramIds" : [ 25520 ],
    "identifier" : "A0A8I3N265",
    "standardIdentifier" : "uniprot:A0A8I3N265",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "MITF" ],
    "parents" : [ 10324019, 10324011, 10326657, 10323929 ],
    "children" : [ ]
  }, {
    "dbId" : 10243342,
    "stId" : "R-CFA-199829",
    "displayName" : "phospho-RPS6KA1 [nucleoplasm]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 49646,
    "diagramIds" : [ 25529 ],
    "identifier" : "A0A8I3NAU2",
    "standardIdentifier" : "uniprot:A0A8I3NAU2",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "RPS6KA1" ],
    "parents" : [ ],
    "children" : [ ]
  }, {
    "dbId" : 10265358,
    "stId" : "R-CFA-381325",
    "displayName" : "EP300 [nucleoplasm]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 49646,
    "identifier" : "A0A8I3P730",
    "standardIdentifier" : "uniprot:A0A8I3P730",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "EP300" ],
    "parents" : [ 10265360 ],
    "children" : [ ]
  }, {
    "dbId" : 10323983,
    "stId" : "R-CFA-379615",
    "displayName" : "QARS1 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 49646,
    "identifier" : "A0A8I3S702",
    "standardIdentifier" : "uniprot:A0A8I3S702",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "QARS1" ],
    "parents" : [ 10323995, 10323993 ],
    "children" : [ ]
  }, {
    "dbId" : 10326664,
    "stId" : "R-CFA-9926321",
    "displayName" : "phospho-MITF [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 49646,
    "diagramIds" : [ 25589 ],
    "identifier" : "A0A8I3N265",
    "standardIdentifier" : "uniprot:A0A8I3N265",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "MITF" ],
    "parents" : [ ],
    "children" : [ ]
  }, {
    "dbId" : 10246666,
    "stId" : "R-CFA-708330",
    "displayName" : "KITLG [extracellular region]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 49646,
    "identifier" : "Q06220",
    "standardIdentifier" : "uniprot:Q06220",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "KITLG" ],
    "parents" : [ 10246668 ],
    "children" : [ ]
  }, {
    "dbId" : 10326667,
    "stId" : "R-CFA-389151",
    "displayName" : "CSF1 dimer [extracellular region]",
    "schemaClass" : "Complex",
    "speciesId" : 49646,
    "diagramIds" : [ 25592 ],
    "parents" : [ ],
    "children" : [ 10316223 ]
  }, {
    "dbId" : 10323979,
    "stId" : "R-CFA-379657",
    "displayName" : "MARS1 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 49646,
    "identifier" : "A0A8I3NFF8",
    "standardIdentifier" : "uniprot:A0A8I3NFF8",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "MARS1" ],
    "parents" : [ 10323995, 10323993 ],
    "children" : [ ]
  }, {
    "dbId" : 10318474,
    "stId" : "R-CFA-9613639",
    "displayName" : "SOX10 [nucleoplasm]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 49646,
    "diagramIds" : [ 25513 ],
    "identifier" : "A0A8I3NB54",
    "standardIdentifier" : "uniprot:A0A8I3NB54",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "SOX10" ],
    "parents" : [ ],
    "children" : [ ]
  }, {
    "dbId" : 10326661,
    "stId" : "R-CFA-9926333",
    "displayName" : "MITF [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 49646,
    "diagramIds" : [ 25587 ],
    "identifier" : "A0A8I3N265",
    "standardIdentifier" : "uniprot:A0A8I3N265",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "MITF" ],
    "parents" : [ ],
    "children" : [ ]
  }, {
    "dbId" : 113560,
    "stId" : "R-ALL-113560",
    "displayName" : "Ac-CoA [nucleoplasm]",
    "schemaClass" : "SimpleEntity",
    "speciesId" : 0,
    "diagramIds" : [ 25565 ],
    "identifier" : "57288",
    "standardIdentifier" : "chebi:57288",
    "referenceType" : "ReferenceMolecule",
    "parents" : [ ],
    "children" : [ ]
  }, {
    "dbId" : 10323975,
    "stId" : "R-CFA-379680",
    "displayName" : "LARS1 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 49646,
    "identifier" : "A0A8I3PH02",
    "standardIdentifier" : "uniprot:A0A8I3PH02",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "LARS1" ],
    "parents" : [ 10323995, 10323993 ],
    "children" : [ ]
  }, {
    "dbId" : 10326657,
    "stId" : "R-CFA-9926393",
    "displayName" : "MITF-M:CREBBP,EP300 [nucleoplasm]",
    "schemaClass" : "Complex",
    "speciesId" : 49646,
    "diagramIds" : [ 25595 ],
    "parents" : [ ],
    "children" : [ 10265360, 10323855 ]
  }, {
    "dbId" : 10323969,
    "stId" : "R-CFA-379568",
    "displayName" : "KARS1 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 49646,
    "identifier" : "A0A8I3PI46",
    "standardIdentifier" : "uniprot:A0A8I3PI46",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "KARS1" ],
    "parents" : [ 10323971 ],
    "children" : [ ]
  }, {
    "dbId" : 10323971,
    "stId" : "R-CFA-379612",
    "displayName" : "KARS homodimer [cytosol]",
    "schemaClass" : "Complex",
    "speciesId" : 49646,
    "parents" : [ 10323993 ],
    "children" : [ 10323969 ]
  }, {
    "dbId" : 10292799,
    "stId" : "R-CFA-5672591",
    "displayName" : "MARK3 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 49646,
    "diagramIds" : [ 25590 ],
    "identifier" : "A0A8I3PDX9",
    "standardIdentifier" : "uniprot:A0A8I3PDX9",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "MARK3" ],
    "parents" : [ ],
    "children" : [ ]
  }, {
    "dbId" : 10316223,
    "stId" : "R-CFA-9009484",
    "displayName" : "CSF1 [extracellular region]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 49646,
    "identifier" : "A0A8I3MKU0",
    "standardIdentifier" : "uniprot:A0A8I3MKU0",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "CSF1" ],
    "parents" : [ 10326667 ],
    "children" : [ ]
  }, {
    "dbId" : 10323897,
    "stId" : "R-CFA-3009365",
    "displayName" : "phospho-AKT3 [nucleoplasm]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 49646,
    "diagramIds" : [ 25548 ],
    "identifier" : "A0A8I3MV00",
    "standardIdentifier" : "uniprot:A0A8I3MV00",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "AKT3" ],
    "parents" : [ ],
    "children" : [ ]
  }, {
    "dbId" : 10323892,
    "stId" : "R-CFA-9825678",
    "displayName" : "TBX3 [nucleoplasm]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 49646,
    "diagramIds" : [ 25545 ],
    "identifier" : "A0A8I3Q583",
    "standardIdentifier" : "uniprot:A0A8I3Q583",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "TBX3" ],
    "parents" : [ ],
    "children" : [ ]
  }, {
    "dbId" : 10323895,
    "stId" : "R-CFA-9825680",
    "displayName" : "phospho-TBX3 [nucleoplasm]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 49646,
    "diagramIds" : [ 25546 ],
    "identifier" : "A0A8I3Q583",
    "standardIdentifier" : "uniprot:A0A8I3Q583",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "TBX3" ],
    "parents" : [ ],
    "children" : [ ]
  }, {
    "dbId" : 10324017,
    "stId" : "R-CFA-9825722",
    "displayName" : "HINT1 dimer:A(5')p4(5')A [nucleoplasm]",
    "schemaClass" : "Complex",
    "speciesId" : 49646,
    "diagramIds" : [ 25581 ],
    "parents" : [ ],
    "children" : [ 10323912, 9825701 ]
  }, {
    "dbId" : 29358,
    "stId" : "R-ALL-29358",
    "displayName" : "ATP [nucleoplasm]",
    "schemaClass" : "SimpleEntity",
    "speciesId" : 0,
    "diagramIds" : [ 25526, 25544, 25560, 25514, 25531, 25519, 25583 ],
    "identifier" : "30616",
    "standardIdentifier" : "chebi:30616",
    "referenceType" : "ReferenceMolecule",
    "parents" : [ ],
    "children" : [ ]
  }, {
    "dbId" : 10324019,
    "stId" : "R-CFA-9825711",
    "displayName" : "MITF-M:p-S207 KARS dimer [nucleoplasm]",
    "schemaClass" : "Complex",
    "speciesId" : 49646,
    "diagramIds" : [ 25580 ],
    "parents" : [ ],
    "children" : [ 10324009, 10323855 ]
  }, {
    "dbId" : 113582,
    "stId" : "R-ALL-113582",
    "displayName" : "ADP [nucleoplasm]",
    "schemaClass" : "SimpleEntity",
    "speciesId" : 0,
    "diagramIds" : [ 25584, 25522, 25528, 25547, 25516, 25532 ],
    "identifier" : "456216",
    "standardIdentifier" : "chebi:456216",
    "referenceType" : "ReferenceMolecule",
    "parents" : [ ],
    "children" : [ ]
  }, {
    "dbId" : 10254003,
    "stId" : "R-CFA-193545",
    "displayName" : "CREBBP [nucleoplasm]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 49646,
    "diagramIds" : [ 25569 ],
    "identifier" : "A0A8I3MJJ8",
    "standardIdentifier" : "uniprot:A0A8I3MJJ8",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "CREBBP" ],
    "parents" : [ 10265360 ],
    "children" : [ ]
  }, {
    "dbId" : 2485002,
    "stId" : "R-ALL-2485002",
    "displayName" : "CoA-SH [nucleoplasm]",
    "schemaClass" : "SimpleEntity",
    "speciesId" : 0,
    "diagramIds" : [ 25568 ],
    "identifier" : "57287",
    "standardIdentifier" : "chebi:57287",
    "referenceType" : "ReferenceMolecule",
    "parents" : [ ],
    "children" : [ ]
  }, {
    "dbId" : 9825701,
    "stId" : "R-ALL-9825701",
    "displayName" : "A(5')p4(5')A [nucleoplasm]",
    "schemaClass" : "SimpleEntity",
    "speciesId" : 0,
    "diagramIds" : [ 25562 ],
    "identifier" : "58141",
    "standardIdentifier" : "chebi:58141",
    "referenceType" : "ReferenceMolecule",
    "parents" : [ 10324017 ],
    "children" : [ ]
  }, {
    "dbId" : 10233519,
    "stId" : "R-CFA-109853",
    "displayName" : "phospho-MAPK1 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 49646,
    "identifier" : "A0A8I3PZP0",
    "standardIdentifier" : "uniprot:A0A8I3PZP0",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "MAPK1" ],
    "parents" : [ 10239187 ],
    "children" : [ ]
  }, {
    "dbId" : 10324009,
    "stId" : "R-CFA-9825717",
    "displayName" : "p-S207 KARS dimer [nucleoplasm]",
    "schemaClass" : "Complex",
    "speciesId" : 49646,
    "diagramIds" : [ 25557 ],
    "parents" : [ 10324019, 10324011 ],
    "children" : [ 10324007 ]
  }, {
    "dbId" : 10324011,
    "stId" : "R-CFA-9825720",
    "displayName" : "MITF-M:HINT1:p-S207 KARS dimer [nucleoplasm]",
    "schemaClass" : "Complex",
    "speciesId" : 49646,
    "diagramIds" : [ 25563 ],
    "parents" : [ ],
    "children" : [ 10323912, 10324009, 10323855 ]
  }, {
    "dbId" : 10323883,
    "stId" : "R-CFA-9824963",
    "displayName" : "phospho-MITF [nucleoplasm]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 49646,
    "diagramIds" : [ 25533 ],
    "identifier" : "A0A8I3N265",
    "standardIdentifier" : "uniprot:A0A8I3N265",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "MITF" ],
    "parents" : [ ],
    "children" : [ ]
  }, {
    "dbId" : 113592,
    "stId" : "R-ALL-113592",
    "displayName" : "ATP [cytosol]",
    "schemaClass" : "SimpleEntity",
    "speciesId" : 0,
    "diagramIds" : [ 25586, 25550 ],
    "identifier" : "30616",
    "standardIdentifier" : "chebi:30616",
    "referenceType" : "ReferenceMolecule",
    "parents" : [ ],
    "children" : [ ]
  }, {
    "dbId" : 10324007,
    "stId" : "R-CFA-9825687",
    "displayName" : "phospho-KARS1 [nucleoplasm]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 49646,
    "identifier" : "A0A8I3PI46",
    "standardIdentifier" : "uniprot:A0A8I3PI46",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "KARS1" ],
    "parents" : [ 10324009 ],
    "children" : [ ]
  }, {
    "dbId" : 29370,
    "stId" : "R-ALL-29370",
    "displayName" : "ADP [cytosol]",
    "schemaClass" : "SimpleEntity",
    "speciesId" : 0,
    "diagramIds" : [ 25553, 25588 ],
    "identifier" : "456216",
    "standardIdentifier" : "chebi:456216",
    "referenceType" : "ReferenceMolecule",
    "parents" : [ ],
    "children" : [ ]
  }, {
    "dbId" : 10255648,
    "stId" : "R-CFA-427531",
    "displayName" : "SIRT1 [nucleoplasm]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 49646,
    "diagramIds" : [ 25575 ],
    "identifier" : "A0A8I3ME48",
    "standardIdentifier" : "uniprot:A0A8I3ME48",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ ],
    "children" : [ ]
  }, {
    "dbId" : 10246689,
    "stId" : "R-CFA-205207",
    "displayName" : "phospho-p-7Y-KIT [plasma membrane]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 49646,
    "identifier" : "O97799",
    "standardIdentifier" : "uniprot:O97799",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 10246691 ],
    "children" : [ ]
  }, {
    "dbId" : 10324000,
    "stId" : "R-CFA-9825714",
    "displayName" : "p-S207 KARS homodimer [cytosol]",
    "schemaClass" : "Complex",
    "speciesId" : 49646,
    "diagramIds" : [ 25552 ],
    "parents" : [ ],
    "children" : [ 10323998 ]
  }, {
    "dbId" : 10323875,
    "stId" : "R-CFA-9824967",
    "displayName" : "phospho-MITF [nucleoplasm]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 49646,
    "diagramIds" : [ 25527 ],
    "identifier" : "A0A8I3N265",
    "standardIdentifier" : "uniprot:A0A8I3N265",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "MITF" ],
    "parents" : [ ],
    "children" : [ ]
  }, {
    "dbId" : 10246691,
    "stId" : "R-CFA-205310",
    "displayName" : "p-7Y-KIT:sSCF dimer:p-7Y-KIT [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 49646,
    "diagramIds" : [ 25524 ],
    "parents" : [ ],
    "children" : [ 10246689, 10246668 ]
  }, {
    "dbId" : 10323929,
    "stId" : "R-CFA-9825723",
    "displayName" : "MITF-M:HINT1 dimer [nucleoplasm]",
    "schemaClass" : "Complex",
    "speciesId" : 49646,
    "diagramIds" : [ 25577 ],
    "parents" : [ ],
    "children" : [ 10323912, 10323855 ]
  }, {
    "dbId" : 10323800,
    "stId" : "R-CFA-9824578",
    "displayName" : "phospho-SOX10 [nucleoplasm]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 49646,
    "diagramIds" : [ 25515 ],
    "identifier" : "A0A8I3NB54",
    "standardIdentifier" : "uniprot:A0A8I3NB54",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "SOX10" ],
    "parents" : [ ],
    "children" : [ ]
  }, {
    "dbId" : 10323924,
    "stId" : "R-CFA-9825712",
    "displayName" : "Ac-K21, K30 HINT1 dimer [nucleoplasm]",
    "schemaClass" : "Complex",
    "speciesId" : 49646,
    "diagramIds" : [ 25567 ],
    "parents" : [ ],
    "children" : [ 10323922 ]
  }, {
    "dbId" : 10239189,
    "stId" : "R-CFA-1268261",
    "displayName" : "p-T,Y MAPK dimers [cytosol]",
    "schemaClass" : "DefinedSet",
    "speciesId" : 49646,
    "diagramIds" : [ 25555 ],
    "parents" : [ ],
    "children" : [ 10239187, 10239185 ]
  }, {
    "dbId" : 10323920,
    "stId" : "R-CFA-9825685-2",
    "displayName" : "LOC100684571 [nucleoplasm]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 49646,
    "identifier" : "A0A8I3Q220",
    "standardIdentifier" : "uniprot:A0A8I3Q220",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "LOC100684571" ],
    "parents" : [ 10323922 ],
    "children" : [ ]
  }, {
    "dbId" : 10239185,
    "stId" : "R-CFA-109844",
    "displayName" : "p-T202, Y204 MAPK3 dimer [cytosol]",
    "schemaClass" : "Complex",
    "speciesId" : 49646,
    "parents" : [ 10239189 ],
    "children" : [ 10239183 ]
  }, {
    "dbId" : 10239187,
    "stId" : "R-CFA-109855",
    "displayName" : "p-T185,Y187 MAPK1 dimer [cytosol]",
    "schemaClass" : "Complex",
    "speciesId" : 49646,
    "diagramIds" : [ 25523, 25517 ],
    "parents" : [ 10239189 ],
    "children" : [ 10233519 ]
  }, {
    "dbId" : 10323922,
    "stId" : "R-CFA-9825685-3",
    "displayName" : "Homologues of Ac-K21,K30 HINT1 [nucleoplasm]",
    "schemaClass" : "DefinedSet",
    "speciesId" : 49646,
    "parents" : [ 10323924 ],
    "children" : [ 10323920, 10323916 ]
  }, {
    "dbId" : 10323916,
    "stId" : "R-CFA-9825685",
    "displayName" : "Ac-K21,K30 HINT1 [nucleoplasm]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 49646,
    "identifier" : "A0A8I3NMM1",
    "standardIdentifier" : "uniprot:A0A8I3NMM1",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 10323922 ],
    "children" : [ ]
  }, {
    "dbId" : 10239183,
    "stId" : "R-CFA-109842",
    "displayName" : "phospho-MAPK3 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 49646,
    "identifier" : "A0A8I3RQD0",
    "standardIdentifier" : "uniprot:A0A8I3RQD0",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "MAPK3" ],
    "parents" : [ 10239185 ],
    "children" : [ ]
  }, {
    "dbId" : 10292425,
    "stId" : "R-CFA-5676549",
    "displayName" : "RANKL trimer [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 49646,
    "diagramIds" : [ 25591 ],
    "parents" : [ ],
    "children" : [ 10292423 ]
  }, {
    "dbId" : 10323912,
    "stId" : "R-CFA-9825721",
    "displayName" : "HINT1 dimer [nucleoplasm]",
    "schemaClass" : "Complex",
    "speciesId" : 49646,
    "diagramIds" : [ 25566 ],
    "parents" : [ 10324017, 10324011, 10323929 ],
    "children" : [ 10323910 ]
  }, {
    "dbId" : 10323908,
    "stId" : "R-CFA-9825679-2",
    "displayName" : "LOC100684571 [nucleoplasm]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 49646,
    "identifier" : "A0A8I3Q220",
    "standardIdentifier" : "uniprot:A0A8I3Q220",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "LOC100684571" ],
    "parents" : [ 10323910 ],
    "children" : [ ]
  }, {
    "dbId" : 10292423,
    "stId" : "R-CFA-5667141",
    "displayName" : "TNFSF11 [plasma membrane]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 49646,
    "identifier" : "A0A8I3NGJ3",
    "standardIdentifier" : "uniprot:A0A8I3NGJ3",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "TNFSF11" ],
    "parents" : [ 10292425 ],
    "children" : [ ]
  }, {
    "dbId" : 10323910,
    "stId" : "R-CFA-9825679-3",
    "displayName" : "Homologues of HINT1 [nucleoplasm]",
    "schemaClass" : "DefinedSet",
    "speciesId" : 49646,
    "parents" : [ 10323912 ],
    "children" : [ 10323904, 10323908 ]
  }, {
    "dbId" : 10323904,
    "stId" : "R-CFA-9825679",
    "displayName" : "HINT1 [nucleoplasm]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 49646,
    "identifier" : "A0A8I3NMM1",
    "standardIdentifier" : "uniprot:A0A8I3NMM1",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 10323910 ],
    "children" : [ ]
  }, {
    "dbId" : 10322496,
    "stId" : "R-CFA-2022823",
    "displayName" : "GSK3B [nucleoplasm]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 49646,
    "diagramIds" : [ 25534 ],
    "identifier" : "A0A8I3P4F2",
    "standardIdentifier" : "uniprot:A0A8I3P4F2",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "GSK3B" ],
    "parents" : [ ],
    "children" : [ ]
  }, {
    "dbId" : 10323965,
    "stId" : "R-CFA-379576",
    "displayName" : "AIMP2 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 49646,
    "identifier" : "A0A8I3NEL4",
    "standardIdentifier" : "uniprot:A0A8I3NEL4",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "AIMP2" ],
    "parents" : [ 10323995, 10323993 ],
    "children" : [ ]
  }, {
    "dbId" : 10323961,
    "stId" : "R-CFA-379641",
    "displayName" : "IARS1 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 49646,
    "identifier" : "A0A8I3M9Y6",
    "standardIdentifier" : "uniprot:A0A8I3M9Y6",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "IARS1" ],
    "parents" : [ 10323995, 10323993 ],
    "children" : [ ]
  }, {
    "dbId" : 10323957,
    "stId" : "R-CFA-379649",
    "displayName" : "EPRS1 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 49646,
    "identifier" : "A0A8I3SBI9",
    "standardIdentifier" : "uniprot:A0A8I3SBI9",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "EPRS1" ],
    "parents" : [ 10323995, 10323993 ],
    "children" : [ ]
  }, {
    "dbId" : 427498,
    "stId" : "R-ALL-427498",
    "displayName" : "2'-O-acetyl-ADP-ribose [nucleoplasm]",
    "schemaClass" : "SimpleEntity",
    "speciesId" : 0,
    "diagramIds" : [ 25574 ],
    "identifier" : "83767",
    "standardIdentifier" : "chebi:83767",
    "referenceType" : "ReferenceMolecule",
    "parents" : [ ],
    "children" : [ ]
  }, {
    "dbId" : 10323953,
    "stId" : "R-CFA-379693",
    "displayName" : "EEF1E1 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 49646,
    "identifier" : "A0A8I3P666",
    "standardIdentifier" : "uniprot:A0A8I3P666",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "EEF1E1" ],
    "parents" : [ 10323995, 10323993 ],
    "children" : [ ]
  }, {
    "dbId" : 113518,
    "stId" : "R-ALL-113518",
    "displayName" : "H2O [nucleoplasm]",
    "schemaClass" : "SimpleEntity",
    "speciesId" : 0,
    "diagramIds" : [ 25571 ],
    "identifier" : "15377",
    "standardIdentifier" : "chebi:15377",
    "referenceType" : "ReferenceMolecule",
    "parents" : [ ],
    "children" : [ ]
  }, {
    "dbId" : 427497,
    "stId" : "R-ALL-427497",
    "displayName" : "NAM [nucleoplasm]",
    "schemaClass" : "SimpleEntity",
    "speciesId" : 0,
    "diagramIds" : [ 25573 ],
    "identifier" : "17154",
    "standardIdentifier" : "chebi:17154",
    "referenceType" : "ReferenceMolecule",
    "parents" : [ ],
    "children" : [ ]
  }, {
    "dbId" : 10323949,
    "stId" : "R-CFA-379685",
    "displayName" : "DARS homodimer [cytosol]",
    "schemaClass" : "Complex",
    "speciesId" : 49646,
    "parents" : [ 10323995, 10323993 ],
    "children" : [ 10323947 ]
  }, {
    "dbId" : 9668967,
    "stId" : "R-ALL-9668967",
    "displayName" : "H+ [nucleoplasm]",
    "schemaClass" : "SimpleEntity",
    "speciesId" : 0,
    "diagramIds" : [ 25559 ],
    "identifier" : "15378",
    "standardIdentifier" : "chebi:15378",
    "referenceType" : "ReferenceMolecule",
    "parents" : [ ],
    "children" : [ ]
  }, {
    "dbId" : 10238697,
    "stId" : "R-CFA-165529",
    "displayName" : "XPO1 [nucleoplasm]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 49646,
    "diagramIds" : [ 25538 ],
    "identifier" : "A0A8I3NNH1",
    "standardIdentifier" : "uniprot:A0A8I3NNH1",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "XPO1" ],
    "parents" : [ 10323866 ],
    "children" : [ ]
  }, {
    "dbId" : 10323947,
    "stId" : "R-CFA-379605",
    "displayName" : "DARS1 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 49646,
    "identifier" : "A0A8I3NDI5",
    "standardIdentifier" : "uniprot:A0A8I3NDI5",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "DARS1" ],
    "parents" : [ 10323949 ],
    "children" : [ ]
  }, {
    "dbId" : 10244836,
    "stId" : "R-CFA-3247784",
    "displayName" : "WNT3A [extracellular region]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 49646,
    "diagramIds" : [ 25535 ],
    "identifier" : "A0A8I3MWK0",
    "standardIdentifier" : "uniprot:A0A8I3MWK0",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "WNT3A" ],
    "parents" : [ ],
    "children" : [ ]
  } ],
  "edges" : [ {
    "dbId" : 10323868,
    "stId" : "R-CFA-9824979",
    "displayName" : "XPO1 binds p-S69,73 MITF-M",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "preceding" : [ 10323888 ],
    "following" : [ 10323872 ],
    "inputs" : [ 10238697, 10323864 ],
    "outputs" : [ 10323866 ],
    "efs" : [ ],
    "diagramIds" : [ 25536 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10323900,
    "stId" : "R-CFA-9825704",
    "displayName" : "AKT3 phosphorylates TBX3",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "inputs" : [ 29358, 10323892 ],
    "outputs" : [ 113582, 10323895 ],
    "catalysts" : [ 10323897 ],
    "efs" : [ ],
    "diagramIds" : [ 25543 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10324024,
    "stId" : "R-CFA-9825790",
    "displayName" : "p-S207 KARS1 dimer synthesizes A(5')p4(5')A",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "preceding" : [ 10324013 ],
    "following" : [ 10324021 ],
    "inputs" : [ 29358, 9668967 ],
    "outputs" : [ 113541, 9825701 ],
    "catalysts" : [ 10324011 ],
    "efs" : [ ],
    "diagramIds" : [ 25558 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10323803,
    "stId" : "R-CFA-9824582",
    "displayName" : "MAPK1 phosphorylates SOX10",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "inputs" : [ 29358, 10318474 ],
    "outputs" : [ 113582, 10323800 ],
    "catalysts" : [ 10239187 ],
    "efs" : [ ],
    "diagramIds" : [ 25512 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10323931,
    "stId" : "R-CFA-9825751",
    "displayName" : "HINT1 binds MITF-M",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "preceding" : [ 10324005 ],
    "following" : [ 10324013 ],
    "inputs" : [ 10323912, 10323855 ],
    "outputs" : [ 10323929 ],
    "efs" : [ ],
    "inhibitors" : [ 10254003 ],
    "activators" : [ 10255648 ],
    "diagramIds" : [ 25576 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10324021,
    "stId" : "R-CFA-9825788",
    "displayName" : "p-S207 KARS displaces HINT1",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "preceding" : [ 10324024 ],
    "inputs" : [ 10324011, 9825701 ],
    "outputs" : [ 10324019, 10324017 ],
    "efs" : [ ],
    "diagramIds" : [ 25579 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10323860,
    "stId" : "R-CFA-9824977",
    "displayName" : "MAPK1-dependent phosphorylation of MITF-M",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "following" : [ 10323888 ],
    "inputs" : [ 29358, 10323855 ],
    "outputs" : [ 113582, 10323858 ],
    "catalysts" : [ 10239187 ],
    "efs" : [ ],
    "activators" : [ 10246691 ],
    "diagramIds" : [ 25518 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10323927,
    "stId" : "R-CFA-9825747",
    "displayName" : "CREBBP acetylates HINT1 dimer",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "preceding" : [ 10324005 ],
    "following" : [ 10324005 ],
    "inputs" : [ 113560, 10323912 ],
    "outputs" : [ 2485002, 10323924 ],
    "catalysts" : [ 10254003 ],
    "efs" : [ ],
    "diagramIds" : [ 25564 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10323888,
    "stId" : "R-CFA-9824999",
    "displayName" : "GSK3B phosphorylates p-S73 MITF-M at residue S69",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "preceding" : [ 10323860 ],
    "following" : [ 10323868 ],
    "inputs" : [ 10323858, 29358 ],
    "outputs" : [ 113582, 10323864 ],
    "catalysts" : [ 10322496 ],
    "efs" : [ ],
    "diagramIds" : [ 25582 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10326669,
    "stId" : "R-CFA-9926483",
    "displayName" : "MARK3 phosphorylates MITF-M on S173",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "inputs" : [ 113592, 10326661 ],
    "outputs" : [ 29370, 10326664 ],
    "catalysts" : [ 10292799 ],
    "efs" : [ ],
    "inhibitors" : [ 10326667, 10292425 ],
    "diagramIds" : [ 25585 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10323885,
    "stId" : "R-CFA-9824995",
    "displayName" : "GSK3B phosphorylates p-S409 MITF-M at S397, S401 and S405",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "preceding" : [ 10323878 ],
    "inputs" : [ 29358, 10323875 ],
    "outputs" : [ 113582, 10323883 ],
    "catalysts" : [ 10322496 ],
    "efs" : [ ],
    "inhibitors" : [ 10244836 ],
    "diagramIds" : [ 25530 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10324013,
    "stId" : "R-CFA-9825782",
    "displayName" : "p-S207 KARS1 dimer binds MITF-M:HINT1 dimer",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "preceding" : [ 10323931, 10324015 ],
    "following" : [ 10324024 ],
    "inputs" : [ 10324009, 10323929 ],
    "outputs" : [ 10324011 ],
    "efs" : [ ],
    "diagramIds" : [ 25578 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10324015,
    "stId" : "R-CFA-9825783",
    "displayName" : "p-S207 KARS1 dimer translocates to the nucleus",
    "schemaClass" : "BlackBoxEvent",
    "speciesId" : 0,
    "preceding" : [ 10324002 ],
    "following" : [ 10324013 ],
    "inputs" : [ 10324000 ],
    "outputs" : [ 10324009 ],
    "efs" : [ ],
    "diagramIds" : [ 25556 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10324005,
    "stId" : "R-CFA-9825772",
    "displayName" : "SIRT1 deacetylates HINT1 dimer",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "preceding" : [ 10323927 ],
    "following" : [ 10323931, 10323927 ],
    "inputs" : [ 113518, 10323924, 427523 ],
    "outputs" : [ 427497, 427498, 10323912 ],
    "catalysts" : [ 10255648 ],
    "efs" : [ ],
    "diagramIds" : [ 25570 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10323878,
    "stId" : "R-CFA-9824994",
    "displayName" : "RPS6KA1-dependent phosphorylation of MITF-M",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "following" : [ 10323885 ],
    "inputs" : [ 29358, 10323855 ],
    "outputs" : [ 113582, 10323875 ],
    "catalysts" : [ 10243342 ],
    "efs" : [ ],
    "activators" : [ 10246691 ],
    "diagramIds" : [ 25525 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10323872,
    "stId" : "R-CFA-9824986",
    "displayName" : "XPO1-dependent export of p-S69,S73 MITF-M",
    "schemaClass" : "BlackBoxEvent",
    "speciesId" : 0,
    "preceding" : [ 10323868 ],
    "inputs" : [ 10323866 ],
    "outputs" : [ 10235924, 10323870 ],
    "efs" : [ ],
    "diagramIds" : [ 25540 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10326659,
    "stId" : "R-CFA-9926478",
    "displayName" : "MITF-M binds CREBBP,EP300",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "inputs" : [ 10265360, 10323855 ],
    "outputs" : [ 10326657 ],
    "efs" : [ ],
    "diagramIds" : [ 25593 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10324002,
    "stId" : "R-CFA-9825759",
    "displayName" : "MAPK-dependent phosphorylation of KARS",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "following" : [ 10324015 ],
    "inputs" : [ 113592, 10323993 ],
    "outputs" : [ 10324000, 29370, 10323995 ],
    "catalysts" : [ 10239189 ],
    "efs" : [ ],
    "activators" : [ 10246691 ],
    "diagramIds" : [ 25549 ],
    "entityFunctionalStatus" : [ ]
  } ]
}