{ "dbId" : 10330259, "stId" : "R-CFA-983712", "speciesName" : "Canis familiaris", "nodes" : [ { "dbId" : 10255516, "stId" : "R-CFA-1297324", "displayName" : "TRPC6 [plasma membrane]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3MK71", "standardIdentifier" : "uniprot:A0A8I3MK71", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "TRPC6" ], "parents" : [ 10282506 ], "children" : [ ] }, { "dbId" : 10255512, "stId" : "R-CFA-426171", "displayName" : "TRPC7 [plasma membrane]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3NUS5", "standardIdentifier" : "uniprot:A0A8I3NUS5", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "TRPC7" ], "parents" : [ 10282506 ], "children" : [ ] }, { "dbId" : 429056, "stId" : "R-ALL-429056", "displayName" : "urate [extracellular region]", "schemaClass" : "SimpleEntity", "speciesId" : 0, "diagramIds" : [ 117701 ], "identifier" : "17775", "standardIdentifier" : "chebi:17775", "referenceType" : "ReferenceMolecule", "parents" : [ ], "children" : [ ] }, { "dbId" : 10255508, "stId" : "R-CFA-426172", "displayName" : "TRPC3 [plasma membrane]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3S1Y6", "standardIdentifier" : "uniprot:A0A8I3S1Y6", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "TRPC3" ], "parents" : [ 10282506 ], "children" : [ ] }, { "dbId" : 111627, "stId" : "R-ALL-111627", "displayName" : "HCO3- [cytosol]", "schemaClass" : "SimpleEntity", "speciesId" : 0, "diagramIds" : [ 117674 ], "identifier" : "17544", "standardIdentifier" : "chebi:17544", "referenceType" : "ReferenceMolecule", "parents" : [ ], "children" : [ ] }, { "dbId" : 10287248, "stId" : "R-CFA-5252043", "displayName" : "ATP13A4, 5 [plasma membrane]", "schemaClass" : "DefinedSet", "speciesId" : 49646, "diagramIds" : [ 117733 ], "parents" : [ ], "children" : [ 10287242, 10287246 ] }, { "dbId" : 428040, "stId" : "R-ALL-428040", "displayName" : "H+ [lysosomal lumen]", "schemaClass" : "SimpleEntity", "speciesId" : 0, "diagramIds" : [ 117689 ], "identifier" : "15378", "standardIdentifier" : "chebi:15378", "referenceType" : "ReferenceMolecule", "parents" : [ ], "children" : [ ] }, { "dbId" : 10287246, "stId" : "R-CFA-939751", "displayName" : "ATP13A5 [plasma membrane]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3Q6V0", "standardIdentifier" : "uniprot:A0A8I3Q6V0", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "ATP13A5" ], "parents" : [ 10287248 ], "children" : [ ] }, { "dbId" : 5692484, "stId" : "R-ALL-5692484", "displayName" : "cation [lysosomal lumen]", "schemaClass" : "SimpleEntity", "speciesId" : 0, "diagramIds" : [ 117747 ], "identifier" : "36916", "standardIdentifier" : "chebi:36916", "referenceType" : "ReferenceMolecule", "parents" : [ ], "children" : [ ] }, { "dbId" : 10287242, "stId" : "R-CFA-939757", "displayName" : "ATP13A4 [plasma membrane]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3PY73", "standardIdentifier" : "uniprot:A0A8I3PY73", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "ATP13A4" ], "parents" : [ 10287248 ], "children" : [ ] }, { "dbId" : 10226816, "stId" : "R-CFA-113595", "displayName" : "Ub [cytosol]", "schemaClass" : "DefinedSet", "speciesId" : 49646, "diagramIds" : [ 117652 ], "parents" : [ ], "children" : [ 10226798, 10226792, 10226788, 10226790 ] }, { "dbId" : 9659575, "stId" : "R-ALL-9659575", "displayName" : "ANO1 inhibitors [extracellular region]", "schemaClass" : "DefinedSet", "speciesId" : 0, "diagramIds" : [ 117798 ], "parents" : [ 10319780 ], "children" : [ 9659596, 9659608, 9659590 ] }, { "dbId" : 2731008, "stId" : "R-ALL-2731008", "displayName" : "Cl- [endosome lumen]", "schemaClass" : "SimpleEntity", "speciesId" : 0, "diagramIds" : [ 117778 ], "identifier" : "17996", "standardIdentifier" : "chebi:17996", "referenceType" : "ReferenceMolecule", "parents" : [ ], "children" : [ ] }, { "dbId" : 188972, "stId" : "R-ALL-188972", "displayName" : "Cl- [extracellular region]", "schemaClass" : "SimpleEntity", "speciesId" : 0, "diagramIds" : [ 117660 ], "identifier" : "17996", "standardIdentifier" : "chebi:17996", "referenceType" : "ReferenceMolecule", "parents" : [ ], "children" : [ ] }, { "dbId" : 139827, "stId" : "R-ALL-139827", "displayName" : "Ca2+ [platelet dense tubular network lumen]", "schemaClass" : "SimpleEntity", "speciesId" : 0, "diagramIds" : [ 117591 ], "identifier" : "29108", "standardIdentifier" : "chebi:29108", "referenceType" : "ReferenceMolecule", "parents" : [ ], "children" : [ ] }, { "dbId" : 9727189, "stId" : "R-ALL-9727189", "displayName" : "PPIs [extracellular region]", "schemaClass" : "CandidateSet", "speciesId" : 0, "diagramIds" : [ 117828 ], "parents" : [ 10321789 ], "children" : [ 9727210, 9727241, 9727193, 9727234, 9727254, 9727190, 9727227, 9727271 ] }, { "dbId" : 9727190, "stId" : "R-ALL-9727190", "displayName" : "esomeprazole [extracellular region]", "schemaClass" : "ChemicalDrug", "speciesId" : 0, "identifier" : "5488", "standardIdentifier" : "iuphar.ligand:5488", "chebiIdentifier" : "chebi:50275", "parents" : [ 9727189 ], "children" : [ ] }, { "dbId" : 10231007, "stId" : "R-CFA-912596", "displayName" : "ATP6V0A1 [endosome membrane]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3RWI5", "standardIdentifier" : "uniprot:A0A8I3RWI5", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "ATP6V0A1" ], "parents" : [ 10231021 ], "children" : [ ] }, { "dbId" : 9701074, "stId" : "R-ALL-9701074", "displayName" : "capsaicin [extracellular region]", "schemaClass" : "ChemicalDrug", "speciesId" : 0, "identifier" : "2486", "standardIdentifier" : "iuphar.ligand:2486", "chebiIdentifier" : "chebi:3374", "parents" : [ 9701105 ], "children" : [ ] }, { "dbId" : 5252122, "stId" : "R-ALL-5252122", "displayName" : "divalent metal cation [extracellular region]", "schemaClass" : "SimpleEntity", "speciesId" : 0, "diagramIds" : [ 117728 ], "identifier" : "60240", "standardIdentifier" : "chebi:60240", "referenceType" : "ReferenceMolecule", "parents" : [ ], "children" : [ ] }, { "dbId" : 9659608, "stId" : "R-ALL-9659608", "displayName" : "crofelemer [extracellular region]", "schemaClass" : "ChemicalDrug", "speciesId" : 0, "identifier" : "7453", "standardIdentifier" : "iuphar.ligand:7453", "parents" : [ 9659575 ], "children" : [ ] }, { "dbId" : 9727193, "stId" : "R-ALL-9727193", "displayName" : "omeprazole [extracellular region]", "schemaClass" : "ChemicalDrug", "speciesId" : 0, "identifier" : "4279", "standardIdentifier" : "iuphar.ligand:4279", "chebiIdentifier" : "chebi:77260", "parents" : [ 9727189 ], "children" : [ ] }, { "dbId" : 9659590, "stId" : "R-ALL-9659590", "displayName" : "niflumic acid [extracellular region]", "schemaClass" : "ChemicalDrug", "speciesId" : 0, "identifier" : "2439", "standardIdentifier" : "iuphar.ligand:2439", "chebiIdentifier" : "chebi:34888", "parents" : [ 9659575 ], "children" : [ ] }, { "dbId" : 9701071, "stId" : "R-ALL-9701071", "displayName" : "resiniferatoxin [extracellular region]", "schemaClass" : "ChemicalDrug", "speciesId" : 0, "identifier" : "2491", "standardIdentifier" : "iuphar.ligand:2491", "chebiIdentifier" : "chebi:8809", "parents" : [ 9701105 ], "children" : [ ] }, { "dbId" : 9659596, "stId" : "R-ALL-9659596", "displayName" : "9-anthroic acid [extracellular region]", "schemaClass" : "ChemicalDrug", "speciesId" : 0, "identifier" : "4113", "standardIdentifier" : "iuphar.ligand:4113", "chebiIdentifier" : "chebi:34507", "parents" : [ 9659575 ], "children" : [ ] }, { "dbId" : 10231039, "stId" : "R-CFA-912599", "displayName" : "ATP6V0D2 [endosome membrane]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3NSM9", "standardIdentifier" : "uniprot:A0A8I3NSM9", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "ATP6V0D2" ], "parents" : [ 10231041 ], "children" : [ ] }, { "dbId" : 9701105, "stId" : "R-ALL-9701105", "displayName" : "TRPV1 agonists [extracellular region]", "schemaClass" : "CandidateSet", "speciesId" : 0, "diagramIds" : [ 117809 ], "parents" : [ 10320667 ], "children" : [ 9701074, 9701121, 9701071, 9701102 ] }, { "dbId" : 167012, "stId" : "R-ALL-167012", "displayName" : "Ca2+ [Golgi lumen]", "schemaClass" : "SimpleEntity", "speciesId" : 0, "diagramIds" : [ 117597 ], "identifier" : "29108", "standardIdentifier" : "chebi:29108", "referenceType" : "ReferenceMolecule", "parents" : [ ], "children" : [ ] }, { "dbId" : 10231035, "stId" : "R-CFA-912592", "displayName" : "ATP6V0D1 [endosome membrane]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3NAA2", "standardIdentifier" : "uniprot:A0A8I3NAA2", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "ATP6V0D1" ], "parents" : [ 10231041 ], "children" : [ ] }, { "dbId" : 10231029, "stId" : "R-CFA-912591", "displayName" : "ATP6V0C [endosome membrane]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3RRR2", "standardIdentifier" : "uniprot:A0A8I3RRR2", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "ATP6V0C" ], "parents" : [ 10231031 ], "children" : [ ] }, { "dbId" : 10231031, "stId" : "R-CFA-912571", "displayName" : "ATP6V0C hexamer [endosome membrane]", "schemaClass" : "Complex", "speciesId" : 49646, "parents" : [ 10231047 ], "children" : [ 10231029 ] }, { "dbId" : 29804, "stId" : "R-ALL-29804", "displayName" : "K+ [cytosol]", "schemaClass" : "SimpleEntity", "speciesId" : 0, "diagramIds" : [ 117825, 117615 ], "identifier" : "29103", "standardIdentifier" : "chebi:29103", "referenceType" : "ReferenceMolecule", "parents" : [ ], "children" : [ ] }, { "dbId" : 10231025, "stId" : "R-CFA-912584", "displayName" : "ATP6V0B [endosome membrane]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3SB94", "standardIdentifier" : "uniprot:A0A8I3SB94", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "ATP6V0B" ], "parents" : [ 10231047 ], "children" : [ ] }, { "dbId" : 10276081, "stId" : "R-CFA-2089937", "displayName" : "TRPC1 [plasma membrane]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3Q281", "standardIdentifier" : "uniprot:A0A8I3Q281", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "TRPC1" ], "parents" : [ 10282506 ], "children" : [ ] }, { "dbId" : 9727227, "stId" : "R-ALL-9727227", "displayName" : "ilaprazole [extracellular region]", "schemaClass" : "ChemicalDrug", "speciesId" : 0, "identifier" : "10512", "standardIdentifier" : "iuphar.ligand:10512", "chebiIdentifier" : "chebi:135544", "parents" : [ 9727189 ], "children" : [ ] }, { "dbId" : 10231021, "stId" : "R-CFA-912594", "displayName" : "ATP6V0A [endosome membrane]", "schemaClass" : "DefinedSet", "speciesId" : 49646, "parents" : [ 10231047 ], "children" : [ 10231011, 10231015, 10231019, 10231007 ] }, { "dbId" : 163953, "stId" : "R-ALL-163953", "displayName" : "H+ [mitochondrial intermembrane space]", "schemaClass" : "SimpleEntity", "speciesId" : 0, "diagramIds" : [ 117712 ], "identifier" : "15378", "standardIdentifier" : "chebi:15378", "referenceType" : "ReferenceMolecule", "parents" : [ ], "children" : [ ] }, { "dbId" : 5692450, "stId" : "R-ALL-5692450", "displayName" : "cation [cytosol]", "schemaClass" : "SimpleEntity", "speciesId" : 0, "diagramIds" : [ 117743 ], "identifier" : "36916", "standardIdentifier" : "chebi:36916", "referenceType" : "ReferenceMolecule", "parents" : [ ], "children" : [ ] }, { "dbId" : 10231019, "stId" : "R-CFA-912587", "displayName" : "TCIRG1 [endosome membrane]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3MZT8", "standardIdentifier" : "uniprot:A0A8I3MZT8", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "TCIRG1" ], "parents" : [ 10231021 ], "children" : [ ] }, { "dbId" : 9701102, "stId" : "R-ALL-9701102", "displayName" : "olvanil [extracellular region]", "schemaClass" : "ChemicalDrug", "speciesId" : 0, "identifier" : "2488", "standardIdentifier" : "iuphar.ligand:2488", "chebiIdentifier" : "chebi:177616", "parents" : [ 9701105 ], "children" : [ ] }, { "dbId" : 10231015, "stId" : "R-CFA-912605", "displayName" : "ATP6V0A4 [endosome membrane]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3ND81", "standardIdentifier" : "uniprot:A0A8I3ND81", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "ATP6V0A4" ], "parents" : [ 10231021 ], "children" : [ ] }, { "dbId" : 9727210, "stId" : "R-ALL-9727210", "displayName" : "lansoprazole [extracellular region]", "schemaClass" : "ChemicalDrug", "speciesId" : 0, "identifier" : "7208", "standardIdentifier" : "iuphar.ligand:7208", "chebiIdentifier" : "chebi:6375", "parents" : [ 9727189 ], "children" : [ ] }, { "dbId" : 10231011, "stId" : "R-CFA-912595", "displayName" : "ATP6V0A2 [endosome membrane]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3P989", "standardIdentifier" : "uniprot:A0A8I3P989", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "ATP6V0A2" ], "parents" : [ 10231021 ], "children" : [ ] }, { "dbId" : 10280476, "stId" : "R-CFA-5333707", "displayName" : "CLCA4 [plasma membrane]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3P948", "standardIdentifier" : "uniprot:A0A8I3P948", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "CLCA4" ], "parents" : [ 10280478 ], "children" : [ ] }, { "dbId" : 10280478, "stId" : "R-CFA-5333722", "displayName" : "N-terminus CLCAs [plasma membrane]", "schemaClass" : "DefinedSet", "speciesId" : 49646, "diagramIds" : [ 117663 ], "parents" : [ ], "children" : [ 10280468, 10280472, 10280476 ] }, { "dbId" : 10262558, "stId" : "R-CFA-939739", "displayName" : "ATP8A1 [plasma membrane]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3S140", "standardIdentifier" : "uniprot:A0A8I3S140", "referenceType" : "ReferenceGeneProduct", "parents" : [ 10262608 ], "children" : [ ] }, { "dbId" : 10254366, "stId" : "R-CFA-427902", "displayName" : "ATP2A3 [platelet dense tubular network membrane]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3S0A4", "standardIdentifier" : "uniprot:A0A8I3S0A4", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "ATP2A3" ], "parents" : [ 10254368 ], "children" : [ ] }, { "dbId" : 10280472, "stId" : "R-CFA-5333668", "displayName" : "CLCA2 [plasma membrane]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3PAS7", "standardIdentifier" : "uniprot:A0A8I3PAS7", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "CLCA2" ], "parents" : [ 10280478 ], "children" : [ ] }, { "dbId" : 10254362, "stId" : "R-CFA-427903", "displayName" : "ATP2A2 [platelet dense tubular network membrane]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "O46674", "standardIdentifier" : "uniprot:O46674", "referenceType" : "ReferenceGeneProduct", "parents" : [ 10254368 ], "children" : [ ] }, { "dbId" : 10280468, "stId" : "R-CFA-5333640", "displayName" : "CLCA1 [plasma membrane]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3P659", "standardIdentifier" : "uniprot:A0A8I3P659", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "CLCA1" ], "parents" : [ 10280478 ], "children" : [ ] }, { "dbId" : 10282517, "stId" : "R-CFA-937284", "displayName" : "TRPM5 [plasma membrane]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3RWJ9", "standardIdentifier" : "uniprot:A0A8I3RWJ9", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "TRPM5" ], "parents" : [ 10282519 ], "children" : [ ] }, { "dbId" : 2892454, "stId" : "R-ALL-2892454", "displayName" : "Na+ [endoplasmic reticulum lumen]", "schemaClass" : "SimpleEntity", "speciesId" : 0, "diagramIds" : [ 117765 ], "identifier" : "29101", "standardIdentifier" : "chebi:29101", "referenceType" : "ReferenceMolecule", "parents" : [ ], "children" : [ ] }, { "dbId" : 10254358, "stId" : "R-CFA-427904", "displayName" : "ATP2A1 [platelet dense tubular network membrane]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3MJQ7", "standardIdentifier" : "uniprot:A0A8I3MJQ7", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "ATP2A1" ], "parents" : [ 10254368 ], "children" : [ ] }, { "dbId" : 10282519, "stId" : "R-CFA-3295585", "displayName" : "TRPM4,5 [plasma membrane]", "schemaClass" : "DefinedSet", "speciesId" : 49646, "diagramIds" : [ 117722 ], "parents" : [ ], "children" : [ 10282513, 10282517 ] }, { "dbId" : 10282513, "stId" : "R-CFA-937288", "displayName" : "TRPM4 [plasma membrane]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3MEX0", "standardIdentifier" : "uniprot:A0A8I3MEX0", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "TRPM4" ], "parents" : [ 10282519 ], "children" : [ ] }, { "dbId" : 10280461, "stId" : "R-CFA-2684954", "displayName" : "ANO9 [plasma membrane]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3Q0M9", "standardIdentifier" : "uniprot:A0A8I3Q0M9", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "ANO9" ], "parents" : [ 10280463 ], "children" : [ ] }, { "dbId" : 10254349, "stId" : "R-CFA-418304", "displayName" : "ATP2B4 [plasma membrane]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3PEN3", "standardIdentifier" : "uniprot:A0A8I3PEN3", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "ATP2B4" ], "parents" : [ 10254351 ], "children" : [ ] }, { "dbId" : 10280463, "stId" : "R-CFA-2684894", "displayName" : "ANOs [plasma membrane]", "schemaClass" : "DefinedSet", "speciesId" : 49646, "diagramIds" : [ 117661 ], "parents" : [ ], "children" : [ 10280449, 10280433, 10280453, 10280437, 10280457, 10280441, 10280461, 10280445, 10280429 ] }, { "dbId" : 10254351, "stId" : "R-CFA-418306", "displayName" : "ATP2B1-4 [plasma membrane]", "schemaClass" : "DefinedSet", "speciesId" : 49646, "diagramIds" : [ 117588 ], "parents" : [ ], "children" : [ 10254337, 10254341, 10254345, 10254349 ] }, { "dbId" : 10282504, "stId" : "R-CFA-937289", "displayName" : "TRPV6 [plasma membrane]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3P620", "standardIdentifier" : "uniprot:A0A8I3P620", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "TRPV6" ], "parents" : [ 10282506 ], "children" : [ ] }, { "dbId" : 10280457, "stId" : "R-CFA-2684888", "displayName" : "ANO8 [plasma membrane]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3Q2P4", "standardIdentifier" : "uniprot:A0A8I3Q2P4", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "ANO8" ], "parents" : [ 10280463 ], "children" : [ ] }, { "dbId" : 10254345, "stId" : "R-CFA-418300", "displayName" : "ATP2B3 [plasma membrane]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3PJ46", "standardIdentifier" : "uniprot:A0A8I3PJ46", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "ATP2B3" ], "parents" : [ 10254351 ], "children" : [ ] }, { "dbId" : 10282506, "stId" : "R-CFA-3295582", "displayName" : "TRPs [plasma membrane]", "schemaClass" : "DefinedSet", "speciesId" : 49646, "diagramIds" : [ 117718 ], "parents" : [ ], "children" : [ 10282466, 10282434, 10282496, 10282470, 10282438, 10282500, 10282474, 10282442, 10282504, 10282446, 10282450, 10276081, 10282454, 10282484, 10255508, 10282458, 10282426, 10282488, 10255512, 10282462, 10282430, 10282492, 10255516 ] }, { "dbId" : 10282500, "stId" : "R-CFA-2671930", "displayName" : "TRPV5 [plasma membrane]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3P285", "standardIdentifier" : "uniprot:A0A8I3P285", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "TRPV5" ], "parents" : [ 10282506 ], "children" : [ ] }, { "dbId" : 10262532, "stId" : "R-CFA-937301", "displayName" : "ATP12A:ATP4B [plasma membrane]", "schemaClass" : "Complex", "speciesId" : 49646, "diagramIds" : [ 117626 ], "parents" : [ ], "children" : [ 10262530, 10262526 ] }, { "dbId" : 10280453, "stId" : "R-CFA-2684922", "displayName" : "ANO7 [plasma membrane]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3PRH5", "standardIdentifier" : "uniprot:A0A8I3PRH5", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "ANO7" ], "parents" : [ 10280463 ], "children" : [ ] }, { "dbId" : 10254341, "stId" : "R-CFA-418303", "displayName" : "ATP2B2 [plasma membrane]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3RVD4", "standardIdentifier" : "uniprot:A0A8I3RVD4", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "ATP2B2" ], "parents" : [ 10254351 ], "children" : [ ] }, { "dbId" : 10282496, "stId" : "R-CFA-1297261", "displayName" : "TRPV4 [plasma membrane]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3PAV3", "standardIdentifier" : "uniprot:A0A8I3PAV3", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "TRPV4" ], "parents" : [ 10282506 ], "children" : [ ] }, { "dbId" : 2730676, "stId" : "R-ALL-2730676", "displayName" : "NAADP [cytosol]", "schemaClass" : "SimpleEntity", "speciesId" : 0, "diagramIds" : [ 117680 ], "identifier" : "76072", "standardIdentifier" : "chebi:76072", "referenceType" : "ReferenceMolecule", "parents" : [ ], "children" : [ ] }, { "dbId" : 10280449, "stId" : "R-CFA-2684941", "displayName" : "ANO6 [plasma membrane]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3Q4Q6", "standardIdentifier" : "uniprot:A0A8I3Q4Q6", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "ANO6" ], "parents" : [ 10280463 ], "children" : [ ] }, { "dbId" : 10254337, "stId" : "R-CFA-418301", "displayName" : "ATP2B1 [plasma membrane]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3NYA8", "standardIdentifier" : "uniprot:A0A8I3NYA8", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "ATP2B1" ], "parents" : [ 10254351 ], "children" : [ ] }, { "dbId" : 10262530, "stId" : "R-CFA-937303", "displayName" : "ATP12A [plasma membrane]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3PX21", "standardIdentifier" : "uniprot:A0A8I3PX21", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "ATP12A" ], "parents" : [ 10262532 ], "children" : [ ] }, { "dbId" : 10280508, "stId" : "R-CFA-2730669", "displayName" : "NALCN:UNC79:UNC80 [plasma membrane]", "schemaClass" : "Complex", "speciesId" : 49646, "diagramIds" : [ 117684 ], "parents" : [ ], "children" : [ 10280498, 10280502, 10280506 ] }, { "dbId" : 10281020, "stId" : "R-CFA-2872467", "displayName" : "SLC17A3 [endoplasmic reticulum membrane]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "diagramIds" : [ 117767 ], "identifier" : "A0A8I3PJ21", "standardIdentifier" : "uniprot:A0A8I3PJ21", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "SLC17A3" ], "parents" : [ ], "children" : [ ] }, { "dbId" : 10262590, "stId" : "R-CFA-939754", "displayName" : "ATP9A [plasma membrane]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3PS86", "standardIdentifier" : "uniprot:A0A8I3PS86", "referenceType" : "ReferenceGeneProduct", "parents" : [ 10262608 ], "children" : [ ] }, { "dbId" : 10280506, "stId" : "R-CFA-2730663", "displayName" : "UNC80 [plasma membrane]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3PJD4", "standardIdentifier" : "uniprot:A0A8I3PJD4", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "UNC80" ], "parents" : [ 10280508 ], "children" : [ ] }, { "dbId" : 10262586, "stId" : "R-CFA-939758", "displayName" : "ATP11A [plasma membrane]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3PMF9", "standardIdentifier" : "uniprot:A0A8I3PMF9", "referenceType" : "ReferenceGeneProduct", "parents" : [ 10262608 ], "children" : [ ] }, { "dbId" : 10280502, "stId" : "R-CFA-2730660", "displayName" : "UNC79 [plasma membrane]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3MKT6", "standardIdentifier" : "uniprot:A0A8I3MKT6", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "UNC79" ], "parents" : [ 10280508 ], "children" : [ ] }, { "dbId" : 1606834, "stId" : "R-ALL-1606834", "displayName" : "Ca2+ [lysosomal lumen]", "schemaClass" : "SimpleEntity", "speciesId" : 0, "diagramIds" : [ 117677 ], "identifier" : "29108", "standardIdentifier" : "chebi:29108", "referenceType" : "ReferenceMolecule", "parents" : [ ], "children" : [ ] }, { "dbId" : 10262582, "stId" : "R-CFA-939764", "displayName" : "ATP10D [plasma membrane]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3RUW2", "standardIdentifier" : "uniprot:A0A8I3RUW2", "referenceType" : "ReferenceGeneProduct", "parents" : [ 10262608 ], "children" : [ ] }, { "dbId" : 10281015, "stId" : "R-CFA-2872485", "displayName" : "SLC17A3 [plasma membrane]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "diagramIds" : [ 117702 ], "identifier" : "A0A8I3PJ21", "standardIdentifier" : "uniprot:A0A8I3PJ21", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "SLC17A3" ], "parents" : [ ], "children" : [ ] }, { "dbId" : 10281008, "stId" : "R-CFA-2889056", "displayName" : "SLC9B1/C2 [plasma membrane]", "schemaClass" : "CandidateSet", "speciesId" : 49646, "diagramIds" : [ 117708 ], "parents" : [ ], "children" : [ 10281002, 10281006 ] }, { "dbId" : 29356, "stId" : "R-ALL-29356", "displayName" : "H2O [cytosol]", "schemaClass" : "SimpleEntity", "speciesId" : 0, "diagramIds" : [ 117729, 117744, 117624, 117736, 117819, 117771, 117610, 117754, 117629, 117596 ], "identifier" : "15377", "standardIdentifier" : "chebi:15377", "referenceType" : "ReferenceMolecule", "parents" : [ ], "children" : [ ] }, { "dbId" : 10280498, "stId" : "R-CFA-2730661", "displayName" : "NALCN [plasma membrane]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3PJ01", "standardIdentifier" : "uniprot:A0A8I3PJ01", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "NALCN" ], "parents" : [ 10280508 ], "children" : [ ] }, { "dbId" : 10262578, "stId" : "R-CFA-939756", "displayName" : "ATP10A [plasma membrane]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3NV67", "standardIdentifier" : "uniprot:A0A8I3NV67", "referenceType" : "ReferenceGeneProduct", "parents" : [ 10262608 ], "children" : [ ] }, { "dbId" : 10281006, "stId" : "R-CFA-2889044", "displayName" : "SLC9C2 [plasma membrane]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3NKC4", "standardIdentifier" : "uniprot:A0A8I3NKC4", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "SLC9C2" ], "parents" : [ 10281008 ], "children" : [ ] }, { "dbId" : 10262574, "stId" : "R-CFA-939750", "displayName" : "ATP11C [plasma membrane]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3SCM5", "standardIdentifier" : "uniprot:A0A8I3SCM5", "referenceType" : "ReferenceGeneProduct", "parents" : [ 10262608 ], "children" : [ ] }, { "dbId" : 10263592, "stId" : "R-CFA-976003", "displayName" : "NEDD4L [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3MIG8", "standardIdentifier" : "uniprot:A0A8I3MIG8", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "NEDD4L" ], "parents" : [ 10280397 ], "children" : [ ] }, { "dbId" : 10280489, "stId" : "R-CFA-2685518", "displayName" : "TPCN2 [lysosomal membrane]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3N106", "standardIdentifier" : "uniprot:A0A8I3N106", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "TPCN2" ], "parents" : [ 10280491 ], "children" : [ ] }, { "dbId" : 10281002, "stId" : "R-CFA-2872499", "displayName" : "SLC9B1 [plasma membrane]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3SA78", "standardIdentifier" : "uniprot:A0A8I3SA78", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "SLC9B1" ], "parents" : [ 10281008 ], "children" : [ ] }, { "dbId" : 10262570, "stId" : "R-CFA-939755", "displayName" : "ATP11B [plasma membrane]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3S1T6", "standardIdentifier" : "uniprot:A0A8I3S1T6", "referenceType" : "ReferenceGeneProduct", "parents" : [ 10262608 ], "children" : [ ] }, { "dbId" : 10280491, "stId" : "R-CFA-2685517", "displayName" : "TPCN1/2 [lysosomal membrane]", "schemaClass" : "DefinedSet", "speciesId" : 49646, "diagramIds" : [ 117679 ], "parents" : [ ], "children" : [ 10280485, 10280489 ] }, { "dbId" : 10280485, "stId" : "R-CFA-2685525", "displayName" : "TPCN1 [lysosomal membrane]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3PDN2", "standardIdentifier" : "uniprot:A0A8I3PDN2", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "TPCN1" ], "parents" : [ 10280491 ], "children" : [ ] }, { "dbId" : 29370, "stId" : "R-ALL-29370", "displayName" : "ADP [cytosol]", "schemaClass" : "SimpleEntity", "speciesId" : 0, "diagramIds" : [ 117617, 117633, 117730, 117746, 117637, 117654, 117739, 117757, 117775, 117598, 117822 ], "identifier" : "456216", "standardIdentifier" : "chebi:456216", "referenceType" : "ReferenceMolecule", "parents" : [ ], "children" : [ ] }, { "dbId" : 10262566, "stId" : "R-CFA-939752", "displayName" : "ATP8B2 [plasma membrane]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3NTU5", "standardIdentifier" : "uniprot:A0A8I3NTU5", "referenceType" : "ReferenceGeneProduct", "parents" : [ 10262608 ], "children" : [ ] }, { "dbId" : 29372, "stId" : "R-ALL-29372", "displayName" : "Pi [cytosol]", "schemaClass" : "SimpleEntity", "speciesId" : 0, "diagramIds" : [ 117616, 117760, 117824, 117632, 117763, 117732, 117748, 117636, 117740, 117772, 117599 ], "identifier" : "43474", "standardIdentifier" : "chebi:43474", "referenceType" : "ReferenceMolecule", "parents" : [ ], "children" : [ ] }, { "dbId" : 10254368, "stId" : "R-CFA-427905", "displayName" : "ATP2A1-3 [platelet dense tubular network membrane]", "schemaClass" : "DefinedSet", "speciesId" : 49646, "diagramIds" : [ 117593 ], "parents" : [ ], "children" : [ 10254358, 10254362, 10254366 ] }, { "dbId" : 10262562, "stId" : "R-CFA-939736", "displayName" : "ATP8B1 [plasma membrane]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3MQM1", "standardIdentifier" : "uniprot:A0A8I3MQM1", "referenceType" : "ReferenceGeneProduct", "parents" : [ 10262608 ], "children" : [ ] }, { "dbId" : 10296413, "stId" : "R-CFA-939762", "displayName" : "ATP13A2 [lysosomal lumen]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "diagramIds" : [ 117749 ], "identifier" : "A0A8I3MMW9", "standardIdentifier" : "uniprot:A0A8I3MMW9", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "ATP13A2" ], "parents" : [ ], "children" : [ ] }, { "dbId" : 9684057, "stId" : "R-ALL-9684057", "displayName" : "acetyldigitoxin [extracellular region]", "schemaClass" : "ChemicalDrug", "speciesId" : 0, "identifier" : "6794", "standardIdentifier" : "iuphar.ligand:6794", "chebiIdentifier" : "chebi:53773", "parents" : [ 9684063 ], "children" : [ ] }, { "dbId" : 10296406, "stId" : "R-CFA-939749", "displayName" : "ATP13A1 [endoplasmic reticulum membrane]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "diagramIds" : [ 117741 ], "identifier" : "A0A8I3NPB9", "standardIdentifier" : "uniprot:A0A8I3NPB9", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "ATP13A1" ], "parents" : [ ], "children" : [ ] }, { "dbId" : 9684063, "stId" : "R-ALL-9684063", "displayName" : "cardiac glycosides [extracellular region]", "schemaClass" : "DefinedSet", "speciesId" : 0, "diagramIds" : [ 117801 ], "parents" : [ 10262448 ], "children" : [ 9684077, 9684057, 9684074, 9684069, 9684082 ] }, { "dbId" : 10262608, "stId" : "R-CFA-939735", "displayName" : "P-type ATPases type IV [plasma membrane]", "schemaClass" : "CandidateSet", "speciesId" : 49646, "diagramIds" : [ 117634 ], "parents" : [ ], "children" : [ 10262578, 10262562, 10262582, 10262566, 10262570, 10262574, 10262558, 10262594, 10262598, 10262602, 10262586, 10262606, 10262590 ] }, { "dbId" : 10280525, "stId" : "R-CFA-2730688", "displayName" : "CLCN4/5/6 [endosome membrane]", "schemaClass" : "DefinedSet", "speciesId" : 49646, "diagramIds" : [ 117782 ], "parents" : [ ], "children" : [ 10280515, 10280519, 10280523 ] }, { "dbId" : 10262606, "stId" : "R-CFA-939745", "displayName" : "ATP8A2 [plasma membrane]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3P728", "standardIdentifier" : "uniprot:A0A8I3P728", "referenceType" : "ReferenceGeneProduct", "parents" : [ 10262608 ], "children" : [ ] }, { "dbId" : 2672379, "stId" : "R-ALL-2672379", "displayName" : "amiloride [extracellular region]", "schemaClass" : "ChemicalDrug", "speciesId" : 0, "diagramIds" : [ 117649, 117644 ], "identifier" : "2421", "standardIdentifier" : "iuphar.ligand:2421", "chebiIdentifier" : "chebi:2639", "parents" : [ 9649961 ], "children" : [ ] }, { "dbId" : 10262602, "stId" : "R-CFA-939740", "displayName" : "ATP10B [plasma membrane]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3MFV6", "standardIdentifier" : "uniprot:A0A8I3MFV6", "referenceType" : "ReferenceGeneProduct", "parents" : [ 10262608 ], "children" : [ ] }, { "dbId" : 10280523, "stId" : "R-CFA-2671911", "displayName" : "CLCN6 [endosome membrane]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3MK25", "standardIdentifier" : "uniprot:A0A8I3MK25", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "CLCN6" ], "parents" : [ 10280525 ], "children" : [ ] }, { "dbId" : 2672383, "stId" : "R-ALL-2672383", "displayName" : "NSAID [extracellular region]", "schemaClass" : "SimpleEntity", "speciesId" : 0, "diagramIds" : [ 117643 ], "identifier" : "35475", "standardIdentifier" : "chebi:35475", "referenceType" : "ReferenceMolecule", "parents" : [ ], "children" : [ ] }, { "dbId" : 10281029, "stId" : "R-CFA-9774552", "displayName" : "SLC9B2 dimer [mitochondrial inner membrane]", "schemaClass" : "Complex", "speciesId" : 49646, "diagramIds" : [ 117714 ], "parents" : [ ], "children" : [ 10281027 ] }, { "dbId" : 10262598, "stId" : "R-CFA-939737", "displayName" : "ATP8B4 [plasma membrane]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3PJZ4", "standardIdentifier" : "uniprot:A0A8I3PJZ4", "referenceType" : "ReferenceGeneProduct", "parents" : [ 10262608 ], "children" : [ ] }, { "dbId" : 10280519, "stId" : "R-CFA-2671939", "displayName" : "CLCN5 [endosome membrane]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3Q8R4", "standardIdentifier" : "uniprot:A0A8I3Q8R4", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "CLCN5" ], "parents" : [ 10280525 ], "children" : [ ] }, { "dbId" : 10228807, "stId" : "R-CFA-9016707", "displayName" : "CALM1 [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "diagramIds" : [ 117698 ], "identifier" : "A0A8I3PNY6", "standardIdentifier" : "uniprot:A0A8I3PNY6", "referenceType" : "ReferenceGeneProduct", "parents" : [ 10234116 ], "children" : [ ] }, { "dbId" : 10262594, "stId" : "R-CFA-939742", "displayName" : "ATP9B [plasma membrane]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3MA13", "standardIdentifier" : "uniprot:A0A8I3MA13", "referenceType" : "ReferenceGeneProduct", "parents" : [ 10262608 ], "children" : [ ] }, { "dbId" : 10280515, "stId" : "R-CFA-2671932", "displayName" : "CLCN4 [endosome membrane]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3PNF9", "standardIdentifier" : "uniprot:A0A8I3PNF9", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "CLCN4" ], "parents" : [ 10280525 ], "children" : [ ] }, { "dbId" : 10281027, "stId" : "R-CFA-2889045", "displayName" : "SLC9B2 [mitochondrial inner membrane]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3PV66", "standardIdentifier" : "uniprot:A0A8I3PV66", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "SLC9B2" ], "parents" : [ 10281029 ], "children" : [ ] }, { "dbId" : 9684082, "stId" : "R-ALL-9684082", "displayName" : "ouabain [extracellular region]", "schemaClass" : "ChemicalDrug", "speciesId" : 0, "identifier" : "4826", "standardIdentifier" : "iuphar.ligand:4826", "chebiIdentifier" : "chebi:472805", "parents" : [ 9684063 ], "children" : [ ] }, { "dbId" : 29418, "stId" : "R-ALL-29418", "displayName" : "Mn2+ [cytosol]", "schemaClass" : "SimpleEntity", "speciesId" : 0, "diagramIds" : [ 117735 ], "identifier" : "29035", "standardIdentifier" : "chebi:29035", "chebiIdentifier" : "chebi:29035", "referenceType" : "ReferenceMolecule", "parents" : [ ], "children" : [ ] }, { "dbId" : 939747, "stId" : "R-ALL-939747", "displayName" : "PS [external side of plasma membrane]", "schemaClass" : "SimpleEntity", "speciesId" : 0, "identifier" : "11750", "standardIdentifier" : "chebi:11750", "referenceType" : "ReferenceMolecule", "parents" : [ 947594 ], "children" : [ ] }, { "dbId" : 10226798, "stId" : "R-CFA-939188", "displayName" : "UBA52 [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "P63050", "standardIdentifier" : "uniprot:P63050", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "UBA52" ], "parents" : [ 10226816 ], "children" : [ ] }, { "dbId" : 10226792, "stId" : "R-CFA-939214", "displayName" : "RPS27A [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3NFB9", "standardIdentifier" : "uniprot:A0A8I3NFB9", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "RPS27A" ], "parents" : [ 10226816 ], "children" : [ ] }, { "dbId" : 1981162, "stId" : "R-ALL-1981162", "displayName" : "Mn2+ [endoplasmic reticulum lumen]", "schemaClass" : "SimpleEntity", "speciesId" : 0, "diagramIds" : [ 117738 ], "identifier" : "29035", "standardIdentifier" : "chebi:29035", "chebiIdentifier" : "chebi:29035", "referenceType" : "ReferenceMolecule", "parents" : [ ], "children" : [ ] }, { "dbId" : 9684069, "stId" : "R-ALL-9684069", "displayName" : "deslanoside [extracellular region]", "schemaClass" : "ChemicalDrug", "speciesId" : 0, "identifier" : "6806", "standardIdentifier" : "iuphar.ligand:6806", "chebiIdentifier" : "chebi:31468", "parents" : [ 9684063 ], "children" : [ ] }, { "dbId" : 10226788, "stId" : "R-CFA-939205", "displayName" : "RPS27A(1-76) [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3NUE4", "standardIdentifier" : "uniprot:A0A8I3NUE4", "referenceType" : "ReferenceGeneProduct", "parents" : [ 10226816 ], "children" : [ ] }, { "dbId" : 9684074, "stId" : "R-ALL-9684074", "displayName" : "digoxin [extracellular region]", "schemaClass" : "ChemicalDrug", "speciesId" : 0, "identifier" : "4726", "standardIdentifier" : "iuphar.ligand:4726", "chebiIdentifier" : "chebi:4551", "parents" : [ 9684063 ], "children" : [ ] }, { "dbId" : 10226790, "stId" : "R-CFA-939203", "displayName" : "UBA52(1-76) [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3PFZ3", "standardIdentifier" : "uniprot:A0A8I3PFZ3", "referenceType" : "ReferenceGeneProduct", "parents" : [ 10226816 ], "children" : [ ] }, { "dbId" : 9684077, "stId" : "R-ALL-9684077", "displayName" : "digitoxin [extracellular region]", "schemaClass" : "ChemicalDrug", "speciesId" : 0, "identifier" : "6782", "standardIdentifier" : "iuphar.ligand:6782", "chebiIdentifier" : "chebi:28544", "parents" : [ 9684063 ], "children" : [ ] }, { "dbId" : 939760, "stId" : "R-ALL-939760", "displayName" : "PE [cytoplasmic side of plasma membrane]", "schemaClass" : "SimpleEntity", "speciesId" : 0, "identifier" : "57613", "standardIdentifier" : "chebi:57613", "referenceType" : "ReferenceMolecule", "parents" : [ 947588 ], "children" : [ ] }, { "dbId" : 10280860, "stId" : "R-CFA-2744362", "displayName" : "BEST3 [plasma membrane]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3P370", "standardIdentifier" : "uniprot:A0A8I3P370", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "BEST3" ], "parents" : [ 10280866 ], "children" : [ ] }, { "dbId" : 10280348, "stId" : "R-CFA-2671936", "displayName" : "SCNN1G [plasma membrane]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3MKE6", "standardIdentifier" : "uniprot:A0A8I3MKE6", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "SCNN1G" ], "parents" : [ 10280360 ], "children" : [ ] }, { "dbId" : 10262429, "stId" : "R-CFA-2752084", "displayName" : "FXYD3 [plasma membrane]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3MQA1", "standardIdentifier" : "uniprot:A0A8I3MQA1", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "FXYD3" ], "parents" : [ 10262443 ], "children" : [ ] }, { "dbId" : 10319775, "stId" : "R-CFA-9961464", "displayName" : "ANO1 dimer [plasma membrane]", "schemaClass" : "Complex", "speciesId" : 49646, "diagramIds" : [ 117795 ], "parents" : [ ], "children" : [ 10280429 ] }, { "dbId" : 111875, "stId" : "R-ALL-111875", "displayName" : "Ca2+ [endoplasmic reticulum lumen]", "schemaClass" : "SimpleEntity", "speciesId" : 0, "diagramIds" : [ 117603 ], "identifier" : "29108", "standardIdentifier" : "chebi:29108", "referenceType" : "ReferenceMolecule", "parents" : [ ], "children" : [ ] }, { "dbId" : 10280856, "stId" : "R-CFA-2744359", "displayName" : "BEST2 [plasma membrane]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3RZ58", "standardIdentifier" : "uniprot:A0A8I3RZ58", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "BEST2" ], "parents" : [ 10280866 ], "children" : [ ] }, { "dbId" : 10280344, "stId" : "R-CFA-2671900-3", "displayName" : "Homologues of SCNN1B [plasma membrane]", "schemaClass" : "DefinedSet", "speciesId" : 49646, "parents" : [ 10280385, 10280360 ], "children" : [ 10280338, 10280342 ] }, { "dbId" : 10262425, "stId" : "R-CFA-936805", "displayName" : "FXYD2 [plasma membrane]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3MK29", "standardIdentifier" : "uniprot:A0A8I3MK29", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "FXYD2" ], "parents" : [ 10262443 ], "children" : [ ] }, { "dbId" : 10280852, "stId" : "R-CFA-2744365", "displayName" : "BEST1 [plasma membrane]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3NH80", "standardIdentifier" : "uniprot:A0A8I3NH80", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "BEST1" ], "parents" : [ 10280866 ], "children" : [ ] }, { "dbId" : 10262421, "stId" : "R-CFA-2752086", "displayName" : "FXYD1 [plasma membrane]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3MRH3", "standardIdentifier" : "uniprot:A0A8I3MRH3", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "FXYD1" ], "parents" : [ 10262443 ], "children" : [ ] }, { "dbId" : 10280342, "stId" : "R-CFA-2671900-2", "displayName" : "SCNN1B [plasma membrane]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "Q95165", "standardIdentifier" : "uniprot:Q95165", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "SCNN1B" ], "parents" : [ 10280344 ], "children" : [ ] }, { "dbId" : 10255760, "stId" : "R-CFA-432792", "displayName" : "CAMK2 heteromer [plasma membrane]", "schemaClass" : "Complex", "speciesId" : 49646, "parents" : [ 10255762 ], "children" : [ 10255758, 10255756 ] }, { "dbId" : 10262417, "stId" : "R-CFA-936820", "displayName" : "ATP1B [plasma membrane]", "schemaClass" : "DefinedSet", "speciesId" : 49646, "parents" : [ 10262445 ], "children" : [ 10262407, 10262411, 10262415 ] }, { "dbId" : 10280338, "stId" : "R-CFA-2671900", "displayName" : "SCNN1B [plasma membrane]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3N0E7", "standardIdentifier" : "uniprot:A0A8I3N0E7", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "SCNN1B" ], "parents" : [ 10280344 ], "children" : [ ] }, { "dbId" : 10255762, "stId" : "R-CFA-444601", "displayName" : "CAMK2 heteromer:CALM:4xCa2+ [plasma membrane]", "schemaClass" : "Complex", "speciesId" : 49646, "diagramIds" : [ 117606 ], "parents" : [ ], "children" : [ 10255760, 10234116 ] }, { "dbId" : 10255756, "stId" : "R-CFA-432795", "displayName" : "p-CAMK2A, p-CAMK2B [plasma membrane]", "schemaClass" : "DefinedSet", "speciesId" : 49646, "parents" : [ 10255760 ], "children" : [ 10255754, 10255752 ] }, { "dbId" : 10280845, "stId" : "R-CFA-2895786", "displayName" : "TTYH1 [plasma membrane]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "diagramIds" : [ 117665 ], "identifier" : "A0A8I3RQJ2", "standardIdentifier" : "uniprot:A0A8I3RQJ2", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "TTYH1" ], "parents" : [ ], "children" : [ ] }, { "dbId" : 10255758, "stId" : "R-CFA-432797", "displayName" : "phospho-CAMK2G [plasma membrane]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3RWC7", "standardIdentifier" : "uniprot:A0A8I3RWC7", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "CAMK2G" ], "parents" : [ 10255760 ], "children" : [ ] }, { "dbId" : 352022, "stId" : "R-ALL-352022", "displayName" : "Cl- [cytosol]", "schemaClass" : "SimpleEntity", "speciesId" : 0, "diagramIds" : [ 117781, 117659, 117690 ], "identifier" : "17996", "standardIdentifier" : "chebi:17996", "referenceType" : "ReferenceMolecule", "parents" : [ ], "children" : [ ] }, { "dbId" : 10262415, "stId" : "R-CFA-375073", "displayName" : "ATP1B3 [plasma membrane]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3SBE1", "standardIdentifier" : "uniprot:A0A8I3SBE1", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "ATP1B3" ], "parents" : [ 10262417 ], "children" : [ ] }, { "dbId" : 10255752, "stId" : "R-CFA-432796", "displayName" : "phospho-CAMK2A [plasma membrane]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3NIS8", "standardIdentifier" : "uniprot:A0A8I3NIS8", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "CAMK2A" ], "parents" : [ 10255756 ], "children" : [ ] }, { "dbId" : 2855229, "stId" : "R-ALL-2855229", "displayName" : "Ca2+ [sarcoplasmic reticulum lumen]", "schemaClass" : "SimpleEntity", "speciesId" : 0, "diagramIds" : [ 117693 ], "identifier" : "29108", "standardIdentifier" : "chebi:29108", "referenceType" : "ReferenceMolecule", "parents" : [ ], "children" : [ ] }, { "dbId" : 10255754, "stId" : "R-CFA-432791", "displayName" : "phospho-CAMK2B [plasma membrane]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3NMP2", "standardIdentifier" : "uniprot:A0A8I3NMP2", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "CAMK2B" ], "parents" : [ 10255756 ], "children" : [ ] }, { "dbId" : 10280331, "stId" : "R-CFA-2671913", "displayName" : "ASIC4 [plasma membrane]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "diagramIds" : [ 117642 ], "identifier" : "A0A8I3QXX9", "standardIdentifier" : "uniprot:A0A8I3QXX9", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "ASIC4" ], "parents" : [ ], "children" : [ ] }, { "dbId" : 10262411, "stId" : "R-CFA-375075", "displayName" : "ATP1B2 [plasma membrane]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3PQA5", "standardIdentifier" : "uniprot:A0A8I3PQA5", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "ATP1B2" ], "parents" : [ 10262417 ], "children" : [ ] }, { "dbId" : 10280324, "stId" : "R-CFA-2671891", "displayName" : "ASIC5 trimer:H+ [plasma membrane]", "schemaClass" : "Complex", "speciesId" : 49646, "parents" : [ 10280326 ], "children" : [ 351626, 10280322 ] }, { "dbId" : 10280836, "stId" : "R-CFA-2744217", "displayName" : "TTYH2 [plasma membrane]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3NXW9", "standardIdentifier" : "uniprot:A0A8I3NXW9", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "TTYH2" ], "parents" : [ 10280838 ], "children" : [ ] }, { "dbId" : 10255748, "stId" : "R-CFA-5578813", "displayName" : "phospho-PLN [sarcoplasmic reticulum membrane]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "P61012", "standardIdentifier" : "uniprot:P61012", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "PLN" ], "parents" : [ 10255750 ], "children" : [ ] }, { "dbId" : 10280326, "stId" : "R-CFA-2671886", "displayName" : "ASIC trimers:H+ [plasma membrane]", "schemaClass" : "DefinedSet", "speciesId" : 49646, "diagramIds" : [ 117641 ], "parents" : [ 10308584 ], "children" : [ 10280324, 10280312, 10280318 ] }, { "dbId" : 10280838, "stId" : "R-CFA-2744253", "displayName" : "TTYH2/3 [plasma membrane]", "schemaClass" : "CandidateSet", "speciesId" : 49646, "diagramIds" : [ 117667 ], "parents" : [ ], "children" : [ 10280832, 10280836 ] }, { "dbId" : 10255750, "stId" : "R-CFA-5578810", "displayName" : "p-S16-PLN pentamer [sarcoplasmic reticulum membrane]", "schemaClass" : "Complex", "speciesId" : 49646, "diagramIds" : [ 117605 ], "parents" : [ ], "children" : [ 10255748 ] }, { "dbId" : 10262407, "stId" : "R-CFA-375071", "displayName" : "ATP1B1 [plasma membrane]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3MFG9", "standardIdentifier" : "uniprot:A0A8I3MFG9", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "ATP1B1" ], "parents" : [ 10262417 ], "children" : [ ] }, { "dbId" : 10280832, "stId" : "R-CFA-2744243", "displayName" : "TTYH3 [plasma membrane]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3N0C5", "standardIdentifier" : "uniprot:A0A8I3N0C5", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "TTYH3" ], "parents" : [ 10280838 ], "children" : [ ] }, { "dbId" : 10255745, "stId" : "R-CFA-5578811", "displayName" : "PLN pentamer [sarcoplasmic reticulum membrane]", "schemaClass" : "Complex", "speciesId" : 49646, "diagramIds" : [ 117608 ], "parents" : [ ], "children" : [ 10255743 ] }, { "dbId" : 10262401, "stId" : "R-CFA-936803", "displayName" : "ATP1A3 [plasma membrane]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3MID3", "standardIdentifier" : "uniprot:A0A8I3MID3", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "ATP1A3" ], "parents" : [ 10262403 ], "children" : [ ] }, { "dbId" : 10280322, "stId" : "R-CFA-2671894", "displayName" : "ASIC5 [plasma membrane]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3RW06", "standardIdentifier" : "uniprot:A0A8I3RW06", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "ASIC5" ], "parents" : [ 10319646, 10280324 ], "children" : [ ] }, { "dbId" : 10262403, "stId" : "R-CFA-936779", "displayName" : "ATP1A [plasma membrane]", "schemaClass" : "DefinedSet", "speciesId" : 49646, "parents" : [ 10262445 ], "children" : [ 10262401, 10262393, 10262397 ] }, { "dbId" : 10280892, "stId" : "R-CFA-2855225", "displayName" : "CASQ2 [sarcoplasmic reticulum membrane]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3Q4A3", "standardIdentifier" : "uniprot:A0A8I3Q4A3", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "CASQ2" ], "parents" : [ 10280894 ], "children" : [ ] }, { "dbId" : 74016, "stId" : "R-ALL-74016", "displayName" : "Ca2+ [cytosol]", "schemaClass" : "SimpleEntity", "speciesId" : 0, "diagramIds" : [ 117586, 117685, 117717, 117668, 117804, 117695, 117678, 117662 ], "identifier" : "29108", "standardIdentifier" : "chebi:29108", "referenceType" : "ReferenceMolecule", "parents" : [ 10234116 ], "children" : [ ] }, { "dbId" : 10280381, "stId" : "R-CFA-2684930", "displayName" : "SCNN1A [plasma membrane]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3Q679", "standardIdentifier" : "uniprot:A0A8I3Q679", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "SCNN1A" ], "parents" : [ 10280383 ], "children" : [ ] }, { "dbId" : 10280894, "stId" : "R-CFA-2855188", "displayName" : "CASQ2 polymer [sarcoplasmic reticulum lumen]", "schemaClass" : "Polymer", "speciesId" : 49646, "parents" : [ 10280896 ], "children" : [ 10280892 ] }, { "dbId" : 10282430, "stId" : "R-CFA-3211766", "displayName" : "MCOLN2 [plasma membrane]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3MYU1", "standardIdentifier" : "uniprot:A0A8I3MYU1", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "MCOLN2" ], "parents" : [ 10282506 ], "children" : [ ] }, { "dbId" : 10280383, "stId" : "R-CFA-2684925", "displayName" : "Ub-SCNN1A/SCNN1D [plasma membrane]", "schemaClass" : "DefinedSet", "speciesId" : 49646, "parents" : [ 10280385 ], "children" : [ 10280356, 10280381 ] }, { "dbId" : 10280888, "stId" : "R-CFA-2855198", "displayName" : "CASQ1 polymer [sarcoplasmic reticulum lumen]", "schemaClass" : "Polymer", "speciesId" : 49646, "parents" : [ 10280896 ], "children" : [ 10280886 ] }, { "dbId" : 10282426, "stId" : "R-CFA-3211764", "displayName" : "MCOLN1 [plasma membrane]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3Q7K0", "standardIdentifier" : "uniprot:A0A8I3Q7K0", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "MCOLN1" ], "parents" : [ 10282506 ], "children" : [ ] }, { "dbId" : 10280378, "stId" : "R-CFA-2684953", "displayName" : "SCNN1G [plasma membrane]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3MKE6", "standardIdentifier" : "uniprot:A0A8I3MKE6", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "SCNN1G" ], "parents" : [ 10280385 ], "children" : [ ] }, { "dbId" : 10280886, "stId" : "R-CFA-2855174", "displayName" : "CASQ1 [sarcoplasmic reticulum membrane]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3SCS7", "standardIdentifier" : "uniprot:A0A8I3SCS7", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "CASQ1" ], "parents" : [ 10280888 ], "children" : [ ] }, { "dbId" : 10262448, "stId" : "R-CFA-9684072", "displayName" : "ATP1A:ATP1B:FXYD:cardiac glycosides [plasma membrane]", "schemaClass" : "Complex", "speciesId" : 49646, "diagramIds" : [ 117619 ], "parents" : [ ], "children" : [ 9684063, 10262445 ] }, { "dbId" : 10262445, "stId" : "R-CFA-936770", "displayName" : "ATP1A:ATP1B:FXYD [plasma membrane]", "schemaClass" : "Complex", "speciesId" : 49646, "diagramIds" : [ 117618 ], "parents" : [ 10262448 ], "children" : [ 10262403, 10262417, 10262443 ] }, { "dbId" : 10280360, "stId" : "R-CFA-2672342", "displayName" : "SCNN channels [plasma membrane]", "schemaClass" : "Complex", "speciesId" : 49646, "diagramIds" : [ 117648 ], "parents" : [ ], "children" : [ 10280358, 10280344, 10280348 ] }, { "dbId" : 200503, "stId" : "R-ALL-200503", "displayName" : "Mg2+ [Golgi membrane]", "schemaClass" : "SimpleEntity", "speciesId" : 0, "identifier" : "18420", "standardIdentifier" : "chebi:18420", "referenceType" : "ReferenceMolecule", "parents" : [ 10262379 ], "children" : [ ] }, { "dbId" : 10262441, "stId" : "R-CFA-2752082", "displayName" : "FXYD7 [plasma membrane]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3MM26", "standardIdentifier" : "uniprot:A0A8I3MM26", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "FXYD7" ], "parents" : [ 10262443 ], "children" : [ ] }, { "dbId" : 10262443, "stId" : "R-CFA-2752106", "displayName" : "FXYDs [plasma membrane]", "schemaClass" : "DefinedSet", "speciesId" : 49646, "parents" : [ 10262445 ], "children" : [ 10262433, 10262437, 10262421, 10262441, 10262425, 10262429 ] }, { "dbId" : 10280356, "stId" : "R-CFA-2671902", "displayName" : "SCNN1D [plasma membrane]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3PET1", "standardIdentifier" : "uniprot:A0A8I3PET1", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "SCNN1D" ], "parents" : [ 10280383, 10280358 ], "children" : [ ] }, { "dbId" : 10319780, "stId" : "R-CFA-9659597", "displayName" : "ANO1:ANO1 inhibitors [plasma membrane]", "schemaClass" : "Complex", "speciesId" : 49646, "diagramIds" : [ 117799 ], "parents" : [ ], "children" : [ 9659575, 10280429 ] }, { "dbId" : 10262437, "stId" : "R-CFA-2752104", "displayName" : "FXYD6 [plasma membrane]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3RSR2", "standardIdentifier" : "uniprot:A0A8I3RSR2", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "FXYD6" ], "parents" : [ 10262443 ], "children" : [ ] }, { "dbId" : 10280358, "stId" : "R-CFA-2672355", "displayName" : "SCNN1A/1D [plasma membrane]", "schemaClass" : "DefinedSet", "speciesId" : 49646, "parents" : [ 10280360 ], "children" : [ 10280352, 10280356 ] }, { "dbId" : 10280864, "stId" : "R-CFA-2744358", "displayName" : "BEST4 [plasma membrane]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3PSM5", "standardIdentifier" : "uniprot:A0A8I3PSM5", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "BEST4" ], "parents" : [ 10280866 ], "children" : [ ] }, { "dbId" : 10280352, "stId" : "R-CFA-2671922", "displayName" : "SCNN1A [plasma membrane]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3Q679", "standardIdentifier" : "uniprot:A0A8I3Q679", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "SCNN1A" ], "parents" : [ 10280358 ], "children" : [ ] }, { "dbId" : 10262433, "stId" : "R-CFA-2752081", "displayName" : "FXYD4 [plasma membrane]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3PX80", "standardIdentifier" : "uniprot:A0A8I3PX80", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "FXYD4" ], "parents" : [ 10262443 ], "children" : [ ] }, { "dbId" : 10280866, "stId" : "R-CFA-2744364", "displayName" : "BESTs [plasma membrane]", "schemaClass" : "CandidateSet", "speciesId" : 49646, "diagramIds" : [ 117672 ], "parents" : [ ], "children" : [ 10280852, 10280864, 10280856, 10280860 ] }, { "dbId" : 10280924, "stId" : "R-CFA-5490321", "displayName" : "FKBP1B [sarcoplasmic reticulum membrane]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3PCD4", "standardIdentifier" : "uniprot:A0A8I3PCD4", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "FKBP1B" ], "parents" : [ 10280926 ], "children" : [ ] }, { "dbId" : 10280926, "stId" : "R-CFA-5578817", "displayName" : "FKBP1B tetramer [sarcoplasmic reticulum membrane]", "schemaClass" : "Complex", "speciesId" : 49646, "parents" : [ 10280932 ], "children" : [ 10280924 ] }, { "dbId" : 10282462, "stId" : "R-CFA-2671895", "displayName" : "TRPM3 [plasma membrane]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3MHU7", "standardIdentifier" : "uniprot:A0A8I3MHU7", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "TRPM3" ], "parents" : [ 10282506 ], "children" : [ ] }, { "dbId" : 10280414, "stId" : "R-CFA-2672392", "displayName" : "LRRK1 [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3MH20", "standardIdentifier" : "uniprot:A0A8I3MH20", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "LRRK1" ], "parents" : [ 10280416 ], "children" : [ ] }, { "dbId" : 10280920, "stId" : "R-CFA-2855215", "displayName" : "TRDN [sarcoplasmic reticulum lumen]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3M9N6", "standardIdentifier" : "uniprot:A0A8I3M9N6", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "TRDN" ], "parents" : [ 10280932 ], "children" : [ ] }, { "dbId" : 10280408, "stId" : "R-CFA-2672393", "displayName" : "WNK2 [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3Q8L3", "standardIdentifier" : "uniprot:A0A8I3Q8L3", "referenceType" : "ReferenceGeneProduct", "parents" : [ 10280416 ], "children" : [ ] }, { "dbId" : 10282458, "stId" : "R-CFA-937286", "displayName" : "TRPM2 [plasma membrane]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3PHN0", "standardIdentifier" : "uniprot:A0A8I3PHN0", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "TRPM2" ], "parents" : [ 10282506 ], "children" : [ ] }, { "dbId" : 10280410, "stId" : "R-CFA-2672390", "displayName" : "WNK3 [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3Q8L3", "standardIdentifier" : "uniprot:A0A8I3Q8L3", "referenceType" : "ReferenceGeneProduct", "parents" : [ 10280416 ], "children" : [ ] }, { "dbId" : 10280916, "stId" : "R-CFA-2855176", "displayName" : "RYR tetramers [sarcoplasmic reticulum membrane]", "schemaClass" : "DefinedSet", "speciesId" : 49646, "parents" : [ 10280932 ], "children" : [ 10280914, 10280902, 10280908 ] }, { "dbId" : 9970129, "stId" : "R-ALL-9970129", "displayName" : "Cu1+ [Golgi lumen]", "schemaClass" : "SimpleEntity", "speciesId" : 0, "diagramIds" : [ 117758 ], "identifier" : "49552", "standardIdentifier" : "chebi:49552", "referenceType" : "ReferenceMolecule", "parents" : [ ], "children" : [ ] }, { "dbId" : 10282454, "stId" : "R-CFA-2671907", "displayName" : "TRPM1 [plasma membrane]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3PBJ8", "standardIdentifier" : "uniprot:A0A8I3PBJ8", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "TRPM1" ], "parents" : [ 10282506 ], "children" : [ ] }, { "dbId" : 10280406, "stId" : "R-CFA-2672391", "displayName" : "WNK1 [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3Q8L3", "standardIdentifier" : "uniprot:A0A8I3Q8L3", "referenceType" : "ReferenceGeneProduct", "parents" : [ 10280416 ], "children" : [ ] }, { "dbId" : 10280912, "stId" : "R-CFA-937282", "displayName" : "RYR3 [sarcoplasmic reticulum membrane]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3Q8P6", "standardIdentifier" : "uniprot:A0A8I3Q8P6", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "RYR3" ], "parents" : [ 10280914 ], "children" : [ ] }, { "dbId" : 10280401, "stId" : "R-CFA-2682363", "displayName" : "TSC22D3 [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3S314", "standardIdentifier" : "uniprot:A0A8I3S314", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "TSC22D3" ], "parents" : [ 10280403 ], "children" : [ ] }, { "dbId" : 9970133, "stId" : "R-ALL-9970133", "displayName" : "Cu1+ [extracellular region]", "schemaClass" : "SimpleEntity", "speciesId" : 0, "diagramIds" : [ 117773 ], "identifier" : "49552", "standardIdentifier" : "chebi:49552", "referenceType" : "ReferenceMolecule", "parents" : [ ], "children" : [ ] }, { "dbId" : 10280914, "stId" : "R-CFA-2855220", "displayName" : "RYR3 tetramer [sarcoplasmic reticulum membrane]", "schemaClass" : "Complex", "speciesId" : 49646, "parents" : [ 10280916 ], "children" : [ 10280912 ] }, { "dbId" : 10282450, "stId" : "R-CFA-612170", "displayName" : "TRPC5 [plasma membrane]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3S6T7", "standardIdentifier" : "uniprot:A0A8I3S6T7", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "TRPC5" ], "parents" : [ 10282506 ], "children" : [ ] }, { "dbId" : 10280403, "stId" : "R-CFA-2682342", "displayName" : "RAF1:SGK:TSC22D3:WPP [cytosol]", "schemaClass" : "Complex", "speciesId" : 49646, "diagramIds" : [ 117656 ], "parents" : [ ], "children" : [ 10280401, 10253655, 10280395, 10280397 ] }, { "dbId" : 10280908, "stId" : "R-CFA-2855184", "displayName" : "RYR2 tetramer [sarcoplasmic reticulum membrane]", "schemaClass" : "Complex", "speciesId" : 49646, "parents" : [ 10280916 ], "children" : [ 10280906 ] }, { "dbId" : 10280397, "stId" : "R-CFA-2682366", "displayName" : "WPP1/NEDD4L [cytosol]", "schemaClass" : "DefinedSet", "speciesId" : 49646, "parents" : [ 10280403 ], "children" : [ 10263912, 10263592 ] }, { "dbId" : 30034, "stId" : "R-ALL-30034", "displayName" : "urate [cytosol]", "schemaClass" : "SimpleEntity", "speciesId" : 0, "diagramIds" : [ 117700 ], "identifier" : "17775", "standardIdentifier" : "chebi:17775", "referenceType" : "ReferenceMolecule", "parents" : [ ], "children" : [ ] }, { "dbId" : 10282446, "stId" : "R-CFA-3211767", "displayName" : "TRPC4AP [plasma membrane]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3S366", "standardIdentifier" : "uniprot:A0A8I3S366", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "TRPC4AP" ], "parents" : [ 10282506 ], "children" : [ ] }, { "dbId" : 10280393, "stId" : "R-CFA-2682351", "displayName" : "SGK3 [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3P7M3", "standardIdentifier" : "uniprot:A0A8I3P7M3", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "SGK3" ], "parents" : [ 10280395 ], "children" : [ ] }, { "dbId" : 10280906, "stId" : "R-CFA-937283", "displayName" : "RYR2 [sarcoplasmic reticulum membrane]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3MT21", "standardIdentifier" : "uniprot:A0A8I3MT21", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "RYR2" ], "parents" : [ 10280908 ], "children" : [ ] }, { "dbId" : 10282442, "stId" : "R-CFA-612169", "displayName" : "TRPC4 [plasma membrane]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3PSS9", "standardIdentifier" : "uniprot:A0A8I3PSS9", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "TRPC4" ], "parents" : [ 10282506 ], "children" : [ ] }, { "dbId" : 2889083, "stId" : "R-ALL-2889083", "displayName" : "Na+ [mitochondrial matrix]", "schemaClass" : "SimpleEntity", "speciesId" : 0, "diagramIds" : [ 117713 ], "identifier" : "29101", "standardIdentifier" : "chebi:29101", "referenceType" : "ReferenceMolecule", "parents" : [ ], "children" : [ ] }, { "dbId" : 10280395, "stId" : "R-CFA-2682355", "displayName" : "SGK1/2/3 [cytosol]", "schemaClass" : "DefinedSet", "speciesId" : 49646, "parents" : [ 10280403 ], "children" : [ 10280389, 10280393 ] }, { "dbId" : 10280900, "stId" : "R-CFA-937287", "displayName" : "RYR1 [sarcoplasmic reticulum membrane]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3MXS3", "standardIdentifier" : "uniprot:A0A8I3MXS3", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "RYR1" ], "parents" : [ 10280902 ], "children" : [ ] }, { "dbId" : 10280389, "stId" : "R-CFA-2682356", "displayName" : "SGK1 [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3RSF1", "standardIdentifier" : "uniprot:A0A8I3RSF1", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "SGK1" ], "parents" : [ 10280395 ], "children" : [ ] }, { "dbId" : 10280902, "stId" : "R-CFA-2855211", "displayName" : "RYR1 tetramer [sarcoplasmic reticulum membrane]", "schemaClass" : "Complex", "speciesId" : 49646, "parents" : [ 10280916 ], "children" : [ 10280900 ] }, { "dbId" : 10282438, "stId" : "R-CFA-2671912", "displayName" : "TRPA1 [plasma membrane]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3Q1Q7", "standardIdentifier" : "uniprot:A0A8I3Q1Q7", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "TRPA1" ], "parents" : [ 10320662, 10282506 ], "children" : [ ] }, { "dbId" : 2889072, "stId" : "R-ALL-2889072", "displayName" : "Na+ [mitochondrial intermembrane space]", "schemaClass" : "SimpleEntity", "speciesId" : 0, "diagramIds" : [ 117710 ], "identifier" : "29101", "standardIdentifier" : "chebi:29101", "referenceType" : "ReferenceMolecule", "parents" : [ ], "children" : [ ] }, { "dbId" : 10280896, "stId" : "R-CFA-2855210", "displayName" : "CASQ polymer [sarcoplasmic reticulum lumen]", "schemaClass" : "DefinedSet", "speciesId" : 49646, "parents" : [ 10280932 ], "children" : [ 10280888, 10280894 ] }, { "dbId" : 10280385, "stId" : "R-CFA-2684917", "displayName" : "Ub-SCNN channels [plasma membrane]", "schemaClass" : "Complex", "speciesId" : 49646, "diagramIds" : [ 117655 ], "parents" : [ ], "children" : [ 10280378, 10280344, 10280383 ] }, { "dbId" : 10282434, "stId" : "R-CFA-3211773", "displayName" : "MCOLN3 [plasma membrane]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3MP37", "standardIdentifier" : "uniprot:A0A8I3MP37", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "MCOLN3" ], "parents" : [ 10282506 ], "children" : [ ] }, { "dbId" : 10282492, "stId" : "R-CFA-2671901", "displayName" : "TRPV3 [plasma membrane]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3P6G6", "standardIdentifier" : "uniprot:A0A8I3P6G6", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "TRPV3" ], "parents" : [ 10282506 ], "children" : [ ] }, { "dbId" : 10280445, "stId" : "R-CFA-2684890", "displayName" : "ANO5 [plasma membrane]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3S651", "standardIdentifier" : "uniprot:A0A8I3S651", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "ANO5" ], "parents" : [ 10280463 ], "children" : [ ] }, { "dbId" : 10262526, "stId" : "R-CFA-937307", "displayName" : "ATP4B [plasma membrane]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "P33704", "standardIdentifier" : "uniprot:P33704", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "ATP4B" ], "parents" : [ 10262532, 10321787 ], "children" : [ ] }, { "dbId" : 10282488, "stId" : "R-CFA-2671909", "displayName" : "TRPV2 [plasma membrane]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3N8J6", "standardIdentifier" : "uniprot:A0A8I3N8J6", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "TRPV2" ], "parents" : [ 10282506 ], "children" : [ ] }, { "dbId" : 10280441, "stId" : "R-CFA-2684952", "displayName" : "ANO4 [plasma membrane]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3N6S0", "standardIdentifier" : "uniprot:A0A8I3N6S0", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "ANO4" ], "parents" : [ 10280463 ], "children" : [ ] }, { "dbId" : 10282484, "stId" : "R-CFA-2671938-3", "displayName" : "Homologues of TRPV1 [plasma membrane]", "schemaClass" : "DefinedSet", "speciesId" : 49646, "diagramIds" : [ 117807 ], "parents" : [ 10320674, 10320667, 10282506 ], "children" : [ 10282482, 10282478 ] }, { "dbId" : 10255349, "stId" : "R-CFA-5490313", "displayName" : "SRI [sarcoplasmic reticulum membrane]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "diagramIds" : [ 117607 ], "identifier" : "A0A8I3RY81", "standardIdentifier" : "uniprot:A0A8I3RY81", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "SRI" ], "parents" : [ ], "children" : [ ] }, { "dbId" : 10280437, "stId" : "R-CFA-2684945", "displayName" : "ANO3 [plasma membrane]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3PGN5", "standardIdentifier" : "uniprot:A0A8I3PGN5", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "ANO3" ], "parents" : [ 10280463 ], "children" : [ ] }, { "dbId" : 10280433, "stId" : "R-CFA-2684934", "displayName" : "ANO2 [plasma membrane]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3QA03", "standardIdentifier" : "uniprot:A0A8I3QA03", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "ANO2" ], "parents" : [ 10280463 ], "children" : [ ] }, { "dbId" : 10282482, "stId" : "R-CFA-2671938-2", "displayName" : "TRPV1 [plasma membrane]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "Q697L1", "standardIdentifier" : "uniprot:Q697L1", "referenceType" : "ReferenceGeneProduct", "parents" : [ 10282484 ], "children" : [ ] }, { "dbId" : 10280429, "stId" : "R-CFA-2684927", "displayName" : "ANO1 [plasma membrane]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "diagramIds" : [ 117797 ], "identifier" : "A0A8I3NYL1", "standardIdentifier" : "uniprot:A0A8I3NYL1", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "ANO1" ], "parents" : [ 10319775, 10319780, 10280463 ], "children" : [ ] }, { "dbId" : 10282478, "stId" : "R-CFA-2671938", "displayName" : "TRPV1 [plasma membrane]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3NVQ7", "standardIdentifier" : "uniprot:A0A8I3NVQ7", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "TRPV1" ], "parents" : [ 10282484 ], "children" : [ ] }, { "dbId" : 10308584, "stId" : "R-CFA-8863519", "displayName" : "ASIC trimers:H+:STOML3,(STOM) [plasma membrane]", "schemaClass" : "Complex", "speciesId" : 49646, "diagramIds" : [ 117752 ], "parents" : [ ], "children" : [ 10308582, 10280326 ] }, { "dbId" : 10280937, "stId" : "R-CFA-2684963", "displayName" : "CLIC2 [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "diagramIds" : [ 117697 ], "identifier" : "A0A8I3P560", "standardIdentifier" : "uniprot:A0A8I3P560", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "CLIC2" ], "parents" : [ ], "children" : [ ] }, { "dbId" : 10282474, "stId" : "R-CFA-2671931", "displayName" : "TRPM8 [plasma membrane]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3PRR6", "standardIdentifier" : "uniprot:A0A8I3PRR6", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "TRPM8" ], "parents" : [ 10282506 ], "children" : [ ] }, { "dbId" : 113529, "stId" : "R-ALL-113529", "displayName" : "H+ [mitochondrial matrix]", "schemaClass" : "SimpleEntity", "speciesId" : 0, "diagramIds" : [ 117711 ], "identifier" : "15378", "standardIdentifier" : "chebi:15378", "referenceType" : "ReferenceMolecule", "parents" : [ ], "children" : [ ] }, { "dbId" : 10280932, "stId" : "R-CFA-2855167", "displayName" : "RYR tetramer:FKBP1B tetramer:CASQ polymer:TRDN:junctin [sarcoplasmic reticulum membrane]", "schemaClass" : "Complex", "speciesId" : 49646, "diagramIds" : [ 117694 ], "parents" : [ ], "children" : [ 10280930, 10280896, 10280916, 10280920, 10280926 ] }, { "dbId" : 10308580, "stId" : "R-CFA-8863512", "displayName" : "STOML3 [plasma membrane]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3PY43", "standardIdentifier" : "uniprot:A0A8I3PY43", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "STOML3" ], "parents" : [ 10308582 ], "children" : [ ] }, { "dbId" : 10282470, "stId" : "R-CFA-937281", "displayName" : "TRPM7 [plasma membrane]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3PPS5", "standardIdentifier" : "uniprot:A0A8I3PPS5", "referenceType" : "ReferenceGeneProduct", "parents" : [ 10282506 ], "children" : [ ] }, { "dbId" : 10308582, "stId" : "R-CFA-8863527", "displayName" : "STOML3, (STOM) [plasma membrane]", "schemaClass" : "CandidateSet", "speciesId" : 49646, "diagramIds" : [ 117751 ], "parents" : [ 10308584 ], "children" : [ 10308580, 10300699 ] }, { "dbId" : 10280416, "stId" : "R-CFA-2684956", "displayName" : "WNKs [cytosol]", "schemaClass" : "DefinedSet", "speciesId" : 49646, "diagramIds" : [ 117657 ], "parents" : [ ], "children" : [ 10280406, 10280410, 10280408, 10280414 ] }, { "dbId" : 427899, "stId" : "R-ALL-427899", "displayName" : "H+ [platelet dense tubular network lumen]", "schemaClass" : "SimpleEntity", "speciesId" : 0, "diagramIds" : [ 117590 ], "identifier" : "15378", "standardIdentifier" : "chebi:15378", "referenceType" : "ReferenceMolecule", "parents" : [ ], "children" : [ ] }, { "dbId" : 10280930, "stId" : "R-CFA-5490331", "displayName" : "ASPH [endoplasmic reticulum membrane]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3Q886", "standardIdentifier" : "uniprot:A0A8I3Q886", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "ASPH" ], "parents" : [ 10280932 ], "children" : [ ] }, { "dbId" : 10282466, "stId" : "R-CFA-3211769", "displayName" : "TRPM6 [plasma membrane]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3NMH9", "standardIdentifier" : "uniprot:A0A8I3NMH9", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "TRPM6" ], "parents" : [ 10282506 ], "children" : [ ] }, { "dbId" : 156540, "stId" : "R-ALL-156540", "displayName" : "H+ [endoplasmic reticulum lumen]", "schemaClass" : "SimpleEntity", "speciesId" : 0, "diagramIds" : [ 117602 ], "identifier" : "15378", "standardIdentifier" : "chebi:15378", "referenceType" : "ReferenceMolecule", "parents" : [ ], "children" : [ ] }, { "dbId" : 74113, "stId" : "R-ALL-74113", "displayName" : "Na+ [extracellular region]", "schemaClass" : "SimpleEntity", "speciesId" : 0, "diagramIds" : [ 117682, 117639, 117704, 117720, 117614, 117646 ], "identifier" : "29101", "standardIdentifier" : "chebi:29101", "referenceType" : "ReferenceMolecule", "parents" : [ ], "children" : [ ] }, { "dbId" : 10231069, "stId" : "R-CFA-912586", "displayName" : "ATP6V1C1 [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3NAS2", "standardIdentifier" : "uniprot:A0A8I3NAS2", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "ATP6V1C1" ], "parents" : [ 10231075 ], "children" : [ ] }, { "dbId" : 74112, "stId" : "R-ALL-74112", "displayName" : "Ca2+ [extracellular region]", "schemaClass" : "SimpleEntity", "speciesId" : 0, "diagramIds" : [ 117587, 117716, 117803 ], "identifier" : "29108", "standardIdentifier" : "chebi:29108", "referenceType" : "ReferenceMolecule", "parents" : [ ], "children" : [ ] }, { "dbId" : 10319644, "stId" : "R-CFA-9650161", "displayName" : "ASIC2 trimer [plasma membrane]", "schemaClass" : "Complex", "speciesId" : 49646, "parents" : [ 10319648 ], "children" : [ 10280310 ] }, { "dbId" : 9727254, "stId" : "R-ALL-9727254", "displayName" : "pantoprazole [extracellular region]", "schemaClass" : "ChemicalDrug", "speciesId" : 0, "identifier" : "7260", "standardIdentifier" : "iuphar.ligand:7260", "chebiIdentifier" : "chebi:7915", "parents" : [ 9727189 ], "children" : [ ] }, { "dbId" : 10319646, "stId" : "R-CFA-9650167", "displayName" : "ASIC5 trimer [plasma membrane]", "schemaClass" : "Complex", "speciesId" : 49646, "parents" : [ 10319648 ], "children" : [ 10280322 ] }, { "dbId" : 947594, "stId" : "R-ALL-947594", "displayName" : "APLs [external side of plasma membrane]", "schemaClass" : "DefinedSet", "speciesId" : 0, "diagramIds" : [ 117628 ], "parents" : [ ], "children" : [ 947595, 939747 ] }, { "dbId" : 10231065, "stId" : "R-CFA-912611", "displayName" : "ATP6V1B trimer [cytosol]", "schemaClass" : "Complex", "speciesId" : 49646, "parents" : [ 10231115 ], "children" : [ 10231063 ] }, { "dbId" : 10319640, "stId" : "R-CFA-9649955", "displayName" : "ASIC3 trimer:ASIC3 channel blockers [plasma membrane]", "schemaClass" : "Complex", "speciesId" : 49646, "diagramIds" : [ 117793 ], "parents" : [ ], "children" : [ 10319638, 9649961 ] }, { "dbId" : 947595, "stId" : "R-ALL-947595", "displayName" : "PE [external side of plasma membrane]", "schemaClass" : "SimpleEntity", "speciesId" : 0, "identifier" : "57613", "standardIdentifier" : "chebi:57613", "referenceType" : "ReferenceMolecule", "parents" : [ 947594 ], "children" : [ ] }, { "dbId" : 10300699, "stId" : "R-CFA-6806258", "displayName" : "STOM [plasma membrane]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3P6A5", "standardIdentifier" : "uniprot:A0A8I3P6A5", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "STOM" ], "parents" : [ 10308582 ], "children" : [ ] }, { "dbId" : 10320667, "stId" : "R-CFA-9701107", "displayName" : "TRPV1:TRPV1 agonists [plasma membrane]", "schemaClass" : "Complex", "speciesId" : 49646, "diagramIds" : [ 117810 ], "parents" : [ ], "children" : [ 10282484, 9701105 ] }, { "dbId" : 947592, "stId" : "R-ALL-947592", "displayName" : "PS [cytoplasmic side of plasma membrane]", "schemaClass" : "SimpleEntity", "speciesId" : 0, "identifier" : "11750", "standardIdentifier" : "chebi:11750", "referenceType" : "ReferenceMolecule", "parents" : [ 947588 ], "children" : [ ] }, { "dbId" : 947590, "stId" : "R-ALL-947590", "displayName" : "Pi [plasma membrane]", "schemaClass" : "SimpleEntity", "speciesId" : 0, "diagramIds" : [ 117653 ], "identifier" : "43474", "standardIdentifier" : "chebi:43474", "referenceType" : "ReferenceMolecule", "parents" : [ ], "children" : [ ] }, { "dbId" : 10231061, "stId" : "R-CFA-912598", "displayName" : "ATP6V1B2 [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3Q2N9", "standardIdentifier" : "uniprot:A0A8I3Q2N9", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "ATP6V1B2" ], "parents" : [ 10231063 ], "children" : [ ] }, { "dbId" : 947588, "stId" : "R-ALL-947588", "displayName" : "APLs [cytoplasmic side of plasma membrane]", "schemaClass" : "DefinedSet", "speciesId" : 0, "diagramIds" : [ 117631 ], "parents" : [ ], "children" : [ 947592, 939760 ] }, { "dbId" : 10231063, "stId" : "R-CFA-912593", "displayName" : "ATP6V1B [cytosol]", "schemaClass" : "DefinedSet", "speciesId" : 49646, "parents" : [ 10231065 ], "children" : [ 10231057, 10231061 ] }, { "dbId" : 10319638, "stId" : "R-CFA-9650168", "displayName" : "ASIC3 trimer [plasma membrane]", "schemaClass" : "Complex", "speciesId" : 49646, "diagramIds" : [ 117792 ], "parents" : [ 10319640, 10319648 ], "children" : [ 10280316 ] }, { "dbId" : 10320662, "stId" : "R-CFA-9701182", "displayName" : "TRPA1 tetramer [plasma membrane]", "schemaClass" : "Complex", "speciesId" : 49646, "diagramIds" : [ 117805 ], "parents" : [ 10320678 ], "children" : [ 10282438 ] }, { "dbId" : 10231057, "stId" : "R-CFA-912604", "displayName" : "ATP6V1B1 [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3QKG1", "standardIdentifier" : "uniprot:A0A8I3QKG1", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "ATP6V1B1" ], "parents" : [ 10231063 ], "children" : [ ] }, { "dbId" : 10287377, "stId" : "R-CFA-5333761", "displayName" : "CLCA4 [plasma membrane]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3P948", "standardIdentifier" : "uniprot:A0A8I3P948", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "CLCA4" ], "parents" : [ 10287379 ], "children" : [ ] }, { "dbId" : 113551, "stId" : "R-ALL-113551", "displayName" : "Pi [endoplasmic reticulum lumen]", "schemaClass" : "SimpleEntity", "speciesId" : 0, "diagramIds" : [ 117766 ], "identifier" : "43474", "standardIdentifier" : "chebi:43474", "referenceType" : "ReferenceMolecule", "parents" : [ ], "children" : [ ] }, { "dbId" : 10287379, "stId" : "R-CFA-5333737", "displayName" : "C-terminus CLCAs [plasma membrane]", "schemaClass" : "DefinedSet", "speciesId" : 49646, "diagramIds" : [ 117725 ], "parents" : [ ], "children" : [ 10287377, 10287375, 10287373 ] }, { "dbId" : 351626, "stId" : "R-ALL-351626", "displayName" : "H+ [extracellular region]", "schemaClass" : "SimpleEntity", "speciesId" : 0, "diagramIds" : [ 117625, 117707, 117789, 117823 ], "identifier" : "15378", "standardIdentifier" : "chebi:15378", "referenceType" : "ReferenceMolecule", "parents" : [ 10280324, 10280318, 10280312 ], "children" : [ ] }, { "dbId" : 74126, "stId" : "R-ALL-74126", "displayName" : "K+ [extracellular region]", "schemaClass" : "SimpleEntity", "speciesId" : 0, "diagramIds" : [ 117622, 117821, 117613 ], "identifier" : "29103", "standardIdentifier" : "chebi:29103", "referenceType" : "ReferenceMolecule", "parents" : [ ], "children" : [ ] }, { "dbId" : 10231053, "stId" : "R-CFA-912610", "displayName" : "ATP6V1A trimer [cytosol]", "schemaClass" : "Complex", "speciesId" : 49646, "parents" : [ 10231115 ], "children" : [ 10231051 ] }, { "dbId" : 10287373, "stId" : "R-CFA-5333695", "displayName" : "CLCA1 [plasma membrane]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3P659", "standardIdentifier" : "uniprot:A0A8I3P659", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "CLCA1" ], "parents" : [ 10287379 ], "children" : [ ] }, { "dbId" : 3299744, "stId" : "R-ALL-3299744", "displayName" : "Cu1+ [cytosol]", "schemaClass" : "SimpleEntity", "speciesId" : 0, "diagramIds" : [ 117769, 117756 ], "identifier" : "49552", "standardIdentifier" : "chebi:49552", "referenceType" : "ReferenceMolecule", "parents" : [ ], "children" : [ ] }, { "dbId" : 10287375, "stId" : "R-CFA-5333650", "displayName" : "CLCA2 [plasma membrane]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3PAS7", "standardIdentifier" : "uniprot:A0A8I3PAS7", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "CLCA2" ], "parents" : [ 10287379 ], "children" : [ ] }, { "dbId" : 10287369, "stId" : "R-CFA-2671903", "displayName" : "CLCA4 [plasma membrane]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3P948", "standardIdentifier" : "uniprot:A0A8I3P948", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "CLCA4" ], "parents" : [ 10287371 ], "children" : [ ] }, { "dbId" : 9701121, "stId" : "R-ALL-9701121", "displayName" : "zucapsaicin [extracellular region]", "schemaClass" : "ChemicalDrug", "speciesId" : 0, "identifier" : "11576", "standardIdentifier" : "iuphar.ligand:11576", "chebiIdentifier" : "chebi:135952", "parents" : [ 9701105 ], "children" : [ ] }, { "dbId" : 9727234, "stId" : "R-ALL-9727234", "displayName" : "dexlansoprazole [extracellular region]", "schemaClass" : "ChemicalDrug", "speciesId" : 0, "identifier" : "5487", "standardIdentifier" : "iuphar.ligand:5487", "chebiIdentifier" : "chebi:135931", "parents" : [ 9727189 ], "children" : [ ] }, { "dbId" : 10231051, "stId" : "R-CFA-912602", "displayName" : "ATP6V1A [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3Q434", "standardIdentifier" : "uniprot:A0A8I3Q434", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "ATP6V1A" ], "parents" : [ 10231053 ], "children" : [ ] }, { "dbId" : 10287371, "stId" : "R-CFA-5333763", "displayName" : "CLCAs [plasma membrane]", "schemaClass" : "DefinedSet", "speciesId" : 49646, "diagramIds" : [ 117724 ], "parents" : [ ], "children" : [ 10287367, 10287365, 10287369 ] }, { "dbId" : 10234116, "stId" : "R-CFA-74294", "displayName" : "CALM1:4xCa2+ [cytosol]", "schemaClass" : "Complex", "speciesId" : 49646, "parents" : [ 10255762 ], "children" : [ 10228807, 74016 ] }, { "dbId" : 10231045, "stId" : "R-CFA-912582", "displayName" : "ATP6V0E1 [endosome membrane]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3MGE7", "standardIdentifier" : "uniprot:A0A8I3MGE7", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "ATP6V0E1" ], "parents" : [ 10231047 ], "children" : [ ] }, { "dbId" : 10287365, "stId" : "R-CFA-2671916", "displayName" : "CLCA1 [plasma membrane]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3P659", "standardIdentifier" : "uniprot:A0A8I3P659", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "CLCA1" ], "parents" : [ 10287371 ], "children" : [ ] }, { "dbId" : 10231047, "stId" : "R-CFA-912585", "displayName" : "ATP6V0 [endosome membrane]", "schemaClass" : "Complex", "speciesId" : 49646, "parents" : [ 10231117 ], "children" : [ 10231041, 10231025, 10231031, 10231045, 10231021 ] }, { "dbId" : 10287367, "stId" : "R-CFA-2671920", "displayName" : "CLCA2 [plasma membrane]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3PAS7", "standardIdentifier" : "uniprot:A0A8I3PAS7", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "CLCA2" ], "parents" : [ 10287371 ], "children" : [ ] }, { "dbId" : 10231041, "stId" : "R-CFA-912580", "displayName" : "ATP6V0D [endosome membrane]", "schemaClass" : "DefinedSet", "speciesId" : 49646, "parents" : [ 10231047 ], "children" : [ 10231035, 10231039 ] }, { "dbId" : 9727241, "stId" : "R-ALL-9727241", "displayName" : "rabeprazole [extracellular region]", "schemaClass" : "ChemicalDrug", "speciesId" : 0, "identifier" : "7290", "standardIdentifier" : "iuphar.ligand:7290", "chebiIdentifier" : "chebi:8768", "parents" : [ 9727189 ], "children" : [ ] }, { "dbId" : 9649969, "stId" : "R-ALL-9649969", "displayName" : "diclofenac [extracellular region]", "schemaClass" : "ChemicalDrug", "speciesId" : 0, "identifier" : "2714", "standardIdentifier" : "iuphar.ligand:2714", "chebiIdentifier" : "chebi:47381", "parents" : [ 9649961 ], "children" : [ ] }, { "dbId" : 10231097, "stId" : "R-CFA-912578", "displayName" : "ATP6V1G1 [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3NF98", "standardIdentifier" : "uniprot:A0A8I3NF98", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "ATP6V1G1" ], "parents" : [ 10231107 ], "children" : [ ] }, { "dbId" : 9701171, "stId" : "R-ALL-9701171", "displayName" : "ruthenium red [extracellular region]", "schemaClass" : "ChemicalDrug", "speciesId" : 0, "identifier" : "2432", "standardIdentifier" : "iuphar.ligand:2432", "chebiIdentifier" : "chebi:34956", "parents" : [ 9701157 ], "children" : [ ] }, { "dbId" : 10231093, "stId" : "R-CFA-912603", "displayName" : "ATP6V1F [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3PF77", "standardIdentifier" : "uniprot:A0A8I3PF77", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "ATP6V1F" ], "parents" : [ 10231115 ], "children" : [ ] }, { "dbId" : 10231089, "stId" : "R-CFA-912576", "displayName" : "ATP6V1E [cytosol]", "schemaClass" : "DefinedSet", "speciesId" : 49646, "parents" : [ 10231115 ], "children" : [ 10231083, 10231087 ] }, { "dbId" : 9701157, "stId" : "R-ALL-9701157", "displayName" : "TRPV1 blockers [extracellular region]", "schemaClass" : "DefinedSet", "speciesId" : 0, "diagramIds" : [ 117812 ], "parents" : [ 10320674 ], "children" : [ 9701171, 9701158 ] }, { "dbId" : 9701158, "stId" : "R-ALL-9701158", "displayName" : "capsazepine [extracellular region]", "schemaClass" : "ChemicalDrug", "speciesId" : 0, "identifier" : "2461", "standardIdentifier" : "iuphar.ligand:2461", "chebiIdentifier" : "chebi:70773", "parents" : [ 9701157 ], "children" : [ ] }, { "dbId" : 10231087, "stId" : "R-CFA-912579", "displayName" : "ATP6V1E2 [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3PYI5", "standardIdentifier" : "uniprot:A0A8I3PYI5", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "ATP6V1E2" ], "parents" : [ 10231089 ], "children" : [ ] }, { "dbId" : 9727271, "stId" : "R-ALL-9727271", "displayName" : "tenatoprazole [extracellular region]", "schemaClass" : "ChemicalDrug", "speciesId" : 0, "identifier" : "636411", "standardIdentifier" : "pubchem.compound:636411", "chebiIdentifier" : "chebi:32191", "parents" : [ 9727189 ], "children" : [ ] }, { "dbId" : 9649959, "stId" : "R-ALL-9649959", "displayName" : "aspirin [extracellular region]", "schemaClass" : "ChemicalDrug", "speciesId" : 0, "identifier" : "4139", "standardIdentifier" : "iuphar.ligand:4139", "chebiIdentifier" : "chebi:15365", "parents" : [ 9649961 ], "children" : [ ] }, { "dbId" : 10231083, "stId" : "R-CFA-912606", "displayName" : "ATP6V1E1 [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3QBE3", "standardIdentifier" : "uniprot:A0A8I3QBE3", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "ATP6V1E1" ], "parents" : [ 10231089 ], "children" : [ ] }, { "dbId" : 113592, "stId" : "R-ALL-113592", "displayName" : "ATP [cytosol]", "schemaClass" : "SimpleEntity", "speciesId" : 0, "diagramIds" : [ 117745, 117696, 117651, 117621, 117737, 117755, 117595, 117818, 117770, 117612, 117727, 117630 ], "identifier" : "30616", "standardIdentifier" : "chebi:30616", "referenceType" : "ReferenceMolecule", "parents" : [ ], "children" : [ ] }, { "dbId" : 9649961, "stId" : "R-ALL-9649961", "displayName" : "ASIC3 channel blockers [extracellular region]", "schemaClass" : "DefinedSet", "speciesId" : 0, "diagramIds" : [ 117791 ], "parents" : [ 10319640 ], "children" : [ 9649965, 9649959, 2672379, 9649969 ] }, { "dbId" : 10231079, "stId" : "R-CFA-912597", "displayName" : "ATP6V1D [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3MUZ6", "standardIdentifier" : "uniprot:A0A8I3MUZ6", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "ATP6V1D" ], "parents" : [ 10231115 ], "children" : [ ] }, { "dbId" : 10320678, "stId" : "R-CFA-9701210", "displayName" : "TRPA1 tetramer:TRPA1 antagonists [plasma membrane]", "schemaClass" : "Complex", "speciesId" : 49646, "diagramIds" : [ 117816 ], "parents" : [ ], "children" : [ 9701208, 10320662 ] }, { "dbId" : 10231073, "stId" : "R-CFA-912573", "displayName" : "ATP6V1C2 [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3PSZ6", "standardIdentifier" : "uniprot:A0A8I3PSZ6", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "ATP6V1C2" ], "parents" : [ 10231075 ], "children" : [ ] }, { "dbId" : 10319648, "stId" : "R-CFA-9650164", "displayName" : "ASIC trimers [plasma membrane]", "schemaClass" : "DefinedSet", "speciesId" : 49646, "diagramIds" : [ 117788 ], "parents" : [ ], "children" : [ 10319638, 10319646, 10319644 ] }, { "dbId" : 9649965, "stId" : "R-ALL-9649965", "displayName" : "nafamostat [extracellular region]", "schemaClass" : "ChemicalDrug", "speciesId" : 0, "identifier" : "4262", "standardIdentifier" : "iuphar.ligand:4262", "chebiIdentifier" : "chebi:135466", "parents" : [ 9649961 ], "children" : [ ] }, { "dbId" : 10231075, "stId" : "R-CFA-912577", "displayName" : "ATP6V1C [cytosol]", "schemaClass" : "DefinedSet", "speciesId" : 49646, "parents" : [ 10231115 ], "children" : [ 10231073, 10231069 ] }, { "dbId" : 10320674, "stId" : "R-CFA-9701146", "displayName" : "TRPV1:TRPV1 blockers [plasma membrane]", "schemaClass" : "Complex", "speciesId" : 49646, "diagramIds" : [ 117813 ], "parents" : [ ], "children" : [ 10282484, 9701157 ] }, { "dbId" : 10262364, "stId" : "R-CFA-5358995", "displayName" : "ATP7A:PDZD11 [plasma membrane]", "schemaClass" : "Complex", "speciesId" : 49646, "diagramIds" : [ 117776 ], "parents" : [ ], "children" : [ 10243923, 10262362 ] }, { "dbId" : 10262362, "stId" : "R-CFA-936841", "displayName" : "ATP7A [plasma membrane]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3S4D0", "standardIdentifier" : "uniprot:A0A8I3S4D0", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "ATP7A" ], "parents" : [ 10262364 ], "children" : [ ] }, { "dbId" : 83910, "stId" : "R-ALL-83910", "displayName" : "Na+ [cytosol]", "schemaClass" : "SimpleEntity", "speciesId" : 0, "diagramIds" : [ 117683, 117764, 117721, 117640, 117611, 117706, 117647 ], "identifier" : "29101", "standardIdentifier" : "chebi:29101", "referenceType" : "ReferenceMolecule", "parents" : [ ], "children" : [ ] }, { "dbId" : 9701212, "stId" : "R-ALL-9701212", "displayName" : "metamizole [extracellular region]", "schemaClass" : "ChemicalDrug", "speciesId" : 0, "identifier" : "10608", "standardIdentifier" : "iuphar.ligand:10608", "chebiIdentifier" : "chebi:62088", "parents" : [ 9701208 ], "children" : [ ] }, { "dbId" : 9701214, "stId" : "R-ALL-9701214", "displayName" : "phenazone [extracellular region]", "schemaClass" : "ChemicalDrug", "speciesId" : 0, "identifier" : "2206", "standardIdentifier" : "pubchem.compound:2206", "chebiIdentifier" : "chebi:31225", "parents" : [ 9701208 ], "children" : [ ] }, { "dbId" : 10253655, "stId" : "R-CFA-167205", "displayName" : "RAF1 [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3PZA0", "standardIdentifier" : "uniprot:A0A8I3PZA0", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "RAF1" ], "parents" : [ 10280403 ], "children" : [ ] }, { "dbId" : 10280784, "stId" : "R-CFA-2730944", "displayName" : "OSTM1 [lysosomal membrane]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3NAC3", "standardIdentifier" : "uniprot:A0A8I3NAC3", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "OSTM1" ], "parents" : [ 10280786 ], "children" : [ ] }, { "dbId" : 9701208, "stId" : "R-ALL-9701208", "displayName" : "TRPA1 antagonists [extracellular region]", "schemaClass" : "DefinedSet", "speciesId" : 0, "diagramIds" : [ 117815 ], "parents" : [ 10320678 ], "children" : [ 9701214, 9701212, 9701217 ] }, { "dbId" : 10231121, "stId" : "R-CFA-5215981", "displayName" : "ATP6AP1 [endosome membrane]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "diagramIds" : [ 117784 ], "identifier" : "A0A8I3QRA4", "standardIdentifier" : "uniprot:A0A8I3QRA4", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "ATP6AP1" ], "parents" : [ 10231123 ], "children" : [ ] }, { "dbId" : 10280786, "stId" : "R-CFA-2730964", "displayName" : "CLCN7:OSTM1 [lysosomal membrane]", "schemaClass" : "Complex", "speciesId" : 49646, "diagramIds" : [ 117691 ], "parents" : [ ], "children" : [ 10280784, 10280780 ] }, { "dbId" : 10231123, "stId" : "R-CFA-5252081", "displayName" : "V-ATPase:ATP6AP1 [endosome membrane]", "schemaClass" : "Complex", "speciesId" : 49646, "diagramIds" : [ 117786 ], "parents" : [ ], "children" : [ 10231121, 10231117 ] }, { "dbId" : 10243923, "stId" : "R-CFA-5358989", "displayName" : "PDZD11 [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3Q2U7", "standardIdentifier" : "uniprot:A0A8I3Q2U7", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "PDZD11" ], "parents" : [ 10262364 ], "children" : [ ] }, { "dbId" : 10280780, "stId" : "R-CFA-2671899", "displayName" : "CLCN7 [lysosomal membrane]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3PP54", "standardIdentifier" : "uniprot:A0A8I3PP54", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "CLCN7" ], "parents" : [ 10280786 ], "children" : [ ] }, { "dbId" : 10231117, "stId" : "R-CFA-912600", "displayName" : "V-ATPase [endosome membrane]", "schemaClass" : "Complex", "speciesId" : 49646, "diagramIds" : [ 117785 ], "parents" : [ 10231123 ], "children" : [ 10231047, 10231115 ] }, { "dbId" : 10231113, "stId" : "R-CFA-167578", "displayName" : "ATP6V1H [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3PTB0", "standardIdentifier" : "uniprot:A0A8I3PTB0", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "ATP6V1H" ], "parents" : [ 10231115 ], "children" : [ ] }, { "dbId" : 10231115, "stId" : "R-CFA-912583", "displayName" : "ATP6V1 [cytosol]", "schemaClass" : "Complex", "speciesId" : 49646, "parents" : [ 10231117 ], "children" : [ 10231075, 10231089, 10231079, 10231109, 10231093, 10231113, 10231065, 10231053 ] }, { "dbId" : 425425, "stId" : "R-ALL-425425", "displayName" : "HCO3- [extracellular region]", "schemaClass" : "SimpleEntity", "speciesId" : 0, "diagramIds" : [ 117675 ], "identifier" : "17544", "standardIdentifier" : "chebi:17544", "referenceType" : "ReferenceMolecule", "parents" : [ ], "children" : [ ] }, { "dbId" : 10231109, "stId" : "R-CFA-912608", "displayName" : "ATP6V1G dimer [cytosol]", "schemaClass" : "Complex", "speciesId" : 49646, "parents" : [ 10231115 ], "children" : [ 10231107 ] }, { "dbId" : 70106, "stId" : "R-ALL-70106", "displayName" : "H+ [cytosol]", "schemaClass" : "SimpleEntity", "speciesId" : 0, "diagramIds" : [ 117779, 117623, 117705, 117688, 117592, 117820, 117759, 117774 ], "identifier" : "15378", "standardIdentifier" : "chebi:15378", "referenceType" : "ReferenceMolecule", "parents" : [ ], "children" : [ ] }, { "dbId" : 10231105, "stId" : "R-CFA-912589", "displayName" : "ATP6V1G3 [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3PWA9", "standardIdentifier" : "uniprot:A0A8I3PWA9", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "ATP6V1G3" ], "parents" : [ 10231107 ], "children" : [ ] }, { "dbId" : 2730999, "stId" : "R-ALL-2730999", "displayName" : "Cl- [lysosomal lumen]", "schemaClass" : "SimpleEntity", "speciesId" : 0, "diagramIds" : [ 117687 ], "identifier" : "17996", "standardIdentifier" : "chebi:17996", "referenceType" : "ReferenceMolecule", "parents" : [ ], "children" : [ ] }, { "dbId" : 10231107, "stId" : "R-CFA-912574", "displayName" : "ATP6V1G [cytosol]", "schemaClass" : "DefinedSet", "speciesId" : 49646, "parents" : [ 10231109 ], "children" : [ 10231105, 10231097 ] }, { "dbId" : 10280316, "stId" : "R-CFA-2671888", "displayName" : "ASIC3 [plasma membrane]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3N726", "standardIdentifier" : "uniprot:A0A8I3N726", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "ASIC3" ], "parents" : [ 10319638, 10280318 ], "children" : [ ] }, { "dbId" : 10321789, "stId" : "R-CFA-9727197", "displayName" : "ATP4AATP4B:PPIs [plasma membrane]", "schemaClass" : "Complex", "speciesId" : 49646, "diagramIds" : [ 117829 ], "parents" : [ ], "children" : [ 10321787, 9727189 ] }, { "dbId" : 5252016, "stId" : "R-ALL-5252016", "displayName" : "divalent metal cation [cytosol]", "schemaClass" : "SimpleEntity", "speciesId" : 0, "diagramIds" : [ 117731 ], "identifier" : "60240", "standardIdentifier" : "chebi:60240", "referenceType" : "ReferenceMolecule", "parents" : [ ], "children" : [ ] }, { "dbId" : 10262397, "stId" : "R-CFA-936827", "displayName" : "ATP1A2 [plasma membrane]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3QAS6", "standardIdentifier" : "uniprot:A0A8I3QAS6", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "ATP1A2" ], "parents" : [ 10262403 ], "children" : [ ] }, { "dbId" : 10280318, "stId" : "R-CFA-2671889", "displayName" : "ASIC3 trimer:H+ [plasma membrane]", "schemaClass" : "Complex", "speciesId" : 49646, "parents" : [ 10280326 ], "children" : [ 351626, 10280316 ] }, { "dbId" : 74722, "stId" : "R-ALL-74722", "displayName" : "H+ [endosome lumen]", "schemaClass" : "SimpleEntity", "speciesId" : 0, "diagramIds" : [ 117780 ], "identifier" : "15378", "standardIdentifier" : "chebi:15378", "referenceType" : "ReferenceMolecule", "parents" : [ ], "children" : [ ] }, { "dbId" : 10255743, "stId" : "R-CFA-5490319", "displayName" : "PLN [sarcoplasmic reticulum membrane]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "P61012", "standardIdentifier" : "uniprot:P61012", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "PLN" ], "parents" : [ 10255745 ], "children" : [ ] }, { "dbId" : 10280312, "stId" : "R-CFA-2671887", "displayName" : "ASIC2 trimer:H+ [plasma membrane]", "schemaClass" : "Complex", "speciesId" : 49646, "parents" : [ 10280326 ], "children" : [ 351626, 10280310 ] }, { "dbId" : 10321785, "stId" : "R-CFA-937309", "displayName" : "ATP4A [plasma membrane]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3MMM6", "standardIdentifier" : "uniprot:A0A8I3MMM6", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "ATP4A" ], "parents" : [ 10321787 ], "children" : [ ] }, { "dbId" : 10255736, "stId" : "R-CFA-391965", "displayName" : "ATP2A3 [endoplasmic reticulum membrane]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3S0A4", "standardIdentifier" : "uniprot:A0A8I3S0A4", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "ATP2A3" ], "parents" : [ 10255738 ], "children" : [ ] }, { "dbId" : 10280825, "stId" : "R-CFA-2744251", "displayName" : "CLCN1/2/KA/KB [plasma membrane]", "schemaClass" : "DefinedSet", "speciesId" : 49646, "diagramIds" : [ 117670 ], "parents" : [ ], "children" : [ 10280823, 10280809, 10280813 ] }, { "dbId" : 10262393, "stId" : "R-CFA-936850", "displayName" : "ATP1A1 [plasma membrane]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3SBK9", "standardIdentifier" : "uniprot:A0A8I3SBK9", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "ATP1A1" ], "parents" : [ 10262403 ], "children" : [ ] }, { "dbId" : 10321787, "stId" : "R-CFA-9727185", "displayName" : "ATP4A:ATP4B [plasma membrane]", "schemaClass" : "Complex", "speciesId" : 49646, "diagramIds" : [ 117826 ], "parents" : [ 10321789 ], "children" : [ 10321785, 10262526 ] }, { "dbId" : 10255738, "stId" : "R-CFA-418312", "displayName" : "ATP2A1-3 [endoplasmic reticulum membrane]", "schemaClass" : "DefinedSet", "speciesId" : 49646, "diagramIds" : [ 117604 ], "parents" : [ ], "children" : [ 10255734, 10255732, 10255736 ] }, { "dbId" : 10255732, "stId" : "R-CFA-391961", "displayName" : "ATP2A1 [endoplasmic reticulum membrane]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3MJQ7", "standardIdentifier" : "uniprot:A0A8I3MJQ7", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "ATP2A1" ], "parents" : [ 10255738 ], "children" : [ ] }, { "dbId" : 10280821, "stId" : "R-CFA-2671914", "displayName" : "CLCNK [plasma membrane]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3MUX4", "standardIdentifier" : "uniprot:A0A8I3MUX4", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "CLCNK" ], "parents" : [ 10280823 ], "children" : [ ] }, { "dbId" : 10280310, "stId" : "R-CFA-2671883", "displayName" : "ASIC2 [plasma membrane]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3NHZ8", "standardIdentifier" : "uniprot:A0A8I3NHZ8", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "ASIC2" ], "parents" : [ 10319644, 10280312 ], "children" : [ ] }, { "dbId" : 10255734, "stId" : "R-CFA-391962", "displayName" : "ATP2A2 [endoplasmic reticulum membrane]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "O46674", "standardIdentifier" : "uniprot:O46674", "referenceType" : "ReferenceGeneProduct", "parents" : [ 10255738 ], "children" : [ ] }, { "dbId" : 10280823, "stId" : "R-CFA-2855041", "displayName" : "CLCNKA:BSND [plasma membrane]", "schemaClass" : "Complex", "speciesId" : 49646, "parents" : [ 10280825 ], "children" : [ 10280817, 10280821 ] }, { "dbId" : 10280817, "stId" : "R-CFA-2854996", "displayName" : "BSND [plasma membrane]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3NSX7", "standardIdentifier" : "uniprot:A0A8I3NSX7", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "BSND" ], "parents" : [ 10280823 ], "children" : [ ] }, { "dbId" : 10262386, "stId" : "R-CFA-936912", "displayName" : "ATP7B [Golgi membrane]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "diagramIds" : [ 117761 ], "identifier" : "A0A8I3S4P8", "standardIdentifier" : "uniprot:A0A8I3S4P8", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "ATP7B" ], "parents" : [ ], "children" : [ ] }, { "dbId" : 10280813, "stId" : "R-CFA-2671897", "displayName" : "CLCN2 [plasma membrane]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3Q0B9", "standardIdentifier" : "uniprot:A0A8I3Q0B9", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "CLCN2" ], "parents" : [ 10280825 ], "children" : [ ] }, { "dbId" : 10263912, "stId" : "R-CFA-976037", "displayName" : "WWP1 [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3P4T9", "standardIdentifier" : "uniprot:A0A8I3P4T9", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "WWP1" ], "parents" : [ 10280397 ], "children" : [ ] }, { "dbId" : 10280809, "stId" : "R-CFA-2671925", "displayName" : "CLCN1 [plasma membrane]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "Q9MZT1", "standardIdentifier" : "uniprot:Q9MZT1", "referenceType" : "ReferenceGeneProduct", "parents" : [ 10280825 ], "children" : [ ] }, { "dbId" : 9701217, "stId" : "R-ALL-9701217", "displayName" : "propyphenazone [extracellular region]", "schemaClass" : "ChemicalDrug", "speciesId" : 0, "identifier" : "3778", "standardIdentifier" : "pubchem.compound:3778", "chebiIdentifier" : "chebi:135538", "parents" : [ 9701208 ], "children" : [ ] }, { "dbId" : 10262377, "stId" : "R-CFA-936887", "displayName" : "ATP2C1/2 [Golgi membrane]", "schemaClass" : "DefinedSet", "speciesId" : 49646, "parents" : [ 10262379 ], "children" : [ 10262371, 10262375 ] }, { "dbId" : 10262379, "stId" : "R-CFA-936921", "displayName" : "ATP2C1/2:Mg2+ [Golgi membrane]", "schemaClass" : "Complex", "speciesId" : 49646, "diagramIds" : [ 117600 ], "parents" : [ ], "children" : [ 10262377, 200503 ] }, { "dbId" : 10262375, "stId" : "R-CFA-936773", "displayName" : "ATP2C2 [Golgi membrane]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3MLP6", "standardIdentifier" : "uniprot:A0A8I3MLP6", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "ATP2C2" ], "parents" : [ 10262377 ], "children" : [ ] }, { "dbId" : 10262371, "stId" : "R-CFA-936898", "displayName" : "ATP2C1 [Golgi membrane]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 49646, "identifier" : "A0A8I3QPB8", "standardIdentifier" : "uniprot:A0A8I3QPB8", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "ATP2C1" ], "parents" : [ 10262377 ], "children" : [ ] } ], "edges" : [ { "dbId" : 10320669, "stId" : "R-CFA-9701064", "displayName" : "TRPV1 binds TRPV1 agonists", "schemaClass" : "Reaction", "speciesId" : 0, "inputs" : [ 10282484, 9701105 ], "outputs" : [ 10320667 ], "efs" : [ ], "diagramIds" : [ 117808 ], "entityFunctionalStatus" : [ ] }, { "dbId" : 10262367, "stId" : "R-CFA-936802", "displayName" : "ATP7A transports cytosolic Cu1+ to extracellular region", "schemaClass" : "Reaction", "speciesId" : 0, "inputs" : [ 29356, 113592, 3299744 ], "outputs" : [ 9970133, 29372, 70106, 29370 ], "catalysts" : [ 10262364 ], "efs" : [ ], "diagramIds" : [ 117768 ], "entityFunctionalStatus" : [ ] }, { "dbId" : 10320665, "stId" : "R-CFA-9701055", "displayName" : "TRPA1 tetramer transports Ca2+ from extracellular region to cytosol", "schemaClass" : "Reaction", "speciesId" : 0, "inputs" : [ 74112 ], "outputs" : [ 74016 ], "catalysts" : [ 10320662 ], "efs" : [ ], "diagramIds" : [ 117802 ], "entityFunctionalStatus" : [ ] }, { "dbId" : 10296409, "stId" : "R-CFA-5692462", "displayName" : "ATP13A1 transports Mn2+ from cytosol to ER lumen", "schemaClass" : "Reaction", "speciesId" : 0, "inputs" : [ 29356, 29418, 113592 ], "outputs" : [ 29372, 29370, 1981162 ], "catalysts" : [ 10296406 ], "efs" : [ ], "diagramIds" : [ 117734 ], "entityFunctionalStatus" : [ ] }, { "dbId" : 10282522, "stId" : "R-CFA-3295580", "displayName" : "TRPM4,5 transport extracellular Na+ to cytosol", "schemaClass" : "Reaction", "speciesId" : 0, "inputs" : [ 74113 ], "outputs" : [ 83910 ], "catalysts" : [ 10282519 ], "efs" : [ ], "diagramIds" : [ 117719 ], "entityFunctionalStatus" : [ ] }, { "dbId" : 10319642, "stId" : "R-CFA-9649963", "displayName" : "ASIC3 channel blockers bind ASIC3 trimer", "schemaClass" : "Reaction", "speciesId" : 0, "inputs" : [ 10319638, 9649961 ], "outputs" : [ 10319640 ], "efs" : [ ], "diagramIds" : [ 117790 ], "entityFunctionalStatus" : [ ] }, { "dbId" : 10255764, "stId" : "R-CFA-427910", "displayName" : "ATP2A1-3 transport Ca2+ from cytosol to ER lumen", "schemaClass" : "Reaction", "speciesId" : 0, "inputs" : [ 156540, 74016 ], "outputs" : [ 70106, 111875 ], "catalysts" : [ 10255738 ], "efs" : [ ], "inhibitors" : [ 10255745 ], "activators" : [ 10255762, 10255750, 10255349 ], "diagramIds" : [ 117601 ], "entityFunctionalStatus" : [ ] }, { "dbId" : 10280789, "stId" : "R-CFA-2730959", "displayName" : "CLCN7:OSTM1 exchanges Cl- for H+", "schemaClass" : "Reaction", "speciesId" : 0, "inputs" : [ 2730999, 70106 ], "outputs" : [ 428040, 352022 ], "catalysts" : [ 10280786 ], "efs" : [ ], "diagramIds" : [ 117686 ], "entityFunctionalStatus" : [ ] }, { "dbId" : 10287382, "stId" : "R-CFA-5333671", "displayName" : "CLCAs self cleave", "schemaClass" : "Reaction", "speciesId" : 0, "inputs" : [ 10287371 ], "outputs" : [ 10287379, 10280478 ], "catalysts" : [ 10287371 ], "efs" : [ ], "activators" : [ 74016 ], "diagramIds" : [ 117723 ], "entityFunctionalStatus" : [ ] }, { "dbId" : 10280528, "stId" : "R-CFA-2730692", "displayName" : "CLCN4/5/6 exchange Cl- for H+", "schemaClass" : "Reaction", "speciesId" : 0, "inputs" : [ 70106, 2731008 ], "outputs" : [ 74722, 352022 ], "catalysts" : [ 10280525 ], "efs" : [ ], "diagramIds" : [ 117777 ], "entityFunctionalStatus" : [ ] }, { "dbId" : 10280848, "stId" : "R-CFA-2744349", "displayName" : "TTYH1 transports cytosolic Cl- to extracellular region", "schemaClass" : "Reaction", "speciesId" : 0, "inputs" : [ 352022 ], "outputs" : [ 188972 ], "catalysts" : [ 10280845 ], "efs" : [ ], "diagramIds" : [ 117664 ], "entityFunctionalStatus" : [ ] }, { "dbId" : 10254354, "stId" : "R-CFA-418309", "displayName" : "ATP2B1-4 transport cytosolic Ca2+ to extracellular region", "schemaClass" : "Reaction", "speciesId" : 0, "inputs" : [ 74016 ], "outputs" : [ 74112 ], "catalysts" : [ 10254351 ], "efs" : [ ], "diagramIds" : [ 117585 ], "entityFunctionalStatus" : [ ] }, { "dbId" : 10262611, "stId" : "R-CFA-939763", "displayName" : "P-type ATPases type IV transport external-facing APLs to internal side of the plasma membrane", "schemaClass" : "Reaction", "speciesId" : 0, "inputs" : [ 29356, 113592, 947594 ], "outputs" : [ 29372, 29370, 947588 ], "catalysts" : [ 10262608 ], "efs" : [ ], "diagramIds" : [ 117627 ], "entityFunctionalStatus" : [ ] }, { "dbId" : 10287251, "stId" : "R-CFA-5251989", "displayName" : "ATP13A4,5 transport divalent ions from extracellular region to cytosol", "schemaClass" : "Reaction", "speciesId" : 0, "inputs" : [ 29356, 5252122, 113592 ], "outputs" : [ 29372, 29370, 5252016 ], "catalysts" : [ 10287248 ], "efs" : [ ], "diagramIds" : [ 117726 ], "entityFunctionalStatus" : [ ] }, { "dbId" : 10280333, "stId" : "R-CFA-2671885", "displayName" : "ASIC trimers:H+ transport extracellular Na+ to cytosol", "schemaClass" : "Reaction", "speciesId" : 0, "preceding" : [ 10319650 ], "inputs" : [ 74113 ], "outputs" : [ 83910 ], "catalysts" : [ 10280326 ], "efs" : [ ], "inhibitors" : [ 2672379, 2672383, 10280331 ], "diagramIds" : [ 117638 ], "entityFunctionalStatus" : [ ] }, { "dbId" : 10282509, "stId" : "R-CFA-3295579", "displayName" : "TRPs transport extracellular Ca2+ to cytosol", "schemaClass" : "Reaction", "speciesId" : 0, "inputs" : [ 74112 ], "outputs" : [ 74016 ], "catalysts" : [ 10282506 ], "efs" : [ ], "diagramIds" : [ 117715 ], "entityFunctionalStatus" : [ ] }, { "dbId" : 10287311, "stId" : "R-CFA-5252133", "displayName" : "ATP6AP1 binds V-ATPase", "schemaClass" : "Reaction", "speciesId" : 0, "inputs" : [ 10231121, 10231117 ], "outputs" : [ 10231123 ], "efs" : [ ], "diagramIds" : [ 117783 ], "entityFunctionalStatus" : [ ] }, { "dbId" : 10281032, "stId" : "R-CFA-2889070", "displayName" : "SLC9B2 exchanges Na+ for H+", "schemaClass" : "Reaction", "speciesId" : 0, "inputs" : [ 2889072, 113529 ], "outputs" : [ 2889083, 163953 ], "catalysts" : [ 10281029 ], "efs" : [ ], "diagramIds" : [ 117709 ], "entityFunctionalStatus" : [ ] }, { "dbId" : 10262664, "stId" : "R-CFA-947591", "displayName" : "P-type ATPases type IV transport internal-facing APLs to external side of the plasma membrane", "schemaClass" : "Reaction", "speciesId" : 0, "inputs" : [ 29356, 947588, 113592 ], "outputs" : [ 29372, 29370, 947594 ], "catalysts" : [ 10262608 ], "efs" : [ ], "diagramIds" : [ 117635 ], "entityFunctionalStatus" : [ ] }, { "dbId" : 10280841, "stId" : "R-CFA-2744242", "displayName" : "TTYH2/3 transport cytosolic Cl- to extracellular region", "schemaClass" : "Reaction", "speciesId" : 0, "inputs" : [ 352022 ], "outputs" : [ 188972 ], "catalysts" : [ 10280838 ], "efs" : [ ], "activators" : [ 10280478, 74016 ], "diagramIds" : [ 117666 ], "entityFunctionalStatus" : [ ] }, { "dbId" : 10262535, "stId" : "R-CFA-937311", "displayName" : "ATP12A:ATP4B exchanges K+ for H+", "schemaClass" : "Reaction", "speciesId" : 0, "inputs" : [ 74126, 29356, 70106, 113592 ], "outputs" : [ 351626, 29804, 29372, 29370 ], "catalysts" : [ 10262532 ], "efs" : [ ], "diagramIds" : [ 117620 ], "entityFunctionalStatus" : [ ] }, { "dbId" : 10321794, "stId" : "R-CFA-9727198", "displayName" : "ATP4A:ATP4B exchanges K+ for H+", "schemaClass" : "Reaction", "speciesId" : 0, "inputs" : [ 74126, 29356, 70106, 113592 ], "outputs" : [ 351626, 29804, 29372, 29370 ], "catalysts" : [ 10321787 ], "efs" : [ ], "diagramIds" : [ 117817 ], "entityFunctionalStatus" : [ ] }, { "dbId" : 10280828, "stId" : "R-CFA-2744228", "displayName" : "CLCN1/2/KA/KB transport cytosolic Cl- to extracellular region", "schemaClass" : "Reaction", "speciesId" : 0, "inputs" : [ 352022 ], "outputs" : [ 188972 ], "catalysts" : [ 10280825 ], "efs" : [ ], "diagramIds" : [ 117669 ], "entityFunctionalStatus" : [ ] }, { "dbId" : 10321791, "stId" : "R-CFA-9727188", "displayName" : "ATP4A:ATP4B binds PPIs", "schemaClass" : "Reaction", "speciesId" : 0, "inputs" : [ 10321787, 9727189 ], "outputs" : [ 10321789 ], "efs" : [ ], "diagramIds" : [ 117827 ], "entityFunctionalStatus" : [ ] }, { "dbId" : 10280511, "stId" : "R-CFA-2730664", "displayName" : "UNC79:UNC80:NALCN transports Na+ extracellular region to cytosol", "schemaClass" : "Reaction", "speciesId" : 0, "inputs" : [ 74113 ], "outputs" : [ 83910 ], "catalysts" : [ 10280508 ], "efs" : [ ], "inhibitors" : [ 74016 ], "diagramIds" : [ 117681 ], "entityFunctionalStatus" : [ ] }, { "dbId" : 10281023, "stId" : "R-CFA-2872498", "displayName" : "SLC17A3-1 cotransports extracellular Na+ and Pi to cytosol", "schemaClass" : "Reaction", "speciesId" : 0, "inputs" : [ 29372, 83910 ], "outputs" : [ 113551, 2892454 ], "catalysts" : [ 10281020 ], "efs" : [ ], "diagramIds" : [ 117762 ], "entityFunctionalStatus" : [ ] }, { "dbId" : 10281018, "stId" : "R-CFA-2872497", "displayName" : "SLC17A3-2 transports cytosolic urate to extracellular region", "schemaClass" : "Reaction", "speciesId" : 0, "inputs" : [ 30034 ], "outputs" : [ 429056 ], "catalysts" : [ 10281015 ], "efs" : [ ], "diagramIds" : [ 117699 ], "entityFunctionalStatus" : [ ] }, { "dbId" : 10262389, "stId" : "R-CFA-936895", "displayName" : "ATP7B transports cytosolic Cu1+ to Golgi lumen", "schemaClass" : "Reaction", "speciesId" : 0, "inputs" : [ 29356, 113592, 3299744 ], "outputs" : [ 29372, 70106, 29370, 9970129 ], "catalysts" : [ 10262386 ], "efs" : [ ], "diagramIds" : [ 117753 ], "entityFunctionalStatus" : [ ] }, { "dbId" : 10262450, "stId" : "R-CFA-936897", "displayName" : "ATP1A:ATP1B:FXYD exchanges 3Na+ for 2K+", "schemaClass" : "Reaction", "speciesId" : 0, "inputs" : [ 74126, 29356, 113592, 83910 ], "outputs" : [ 29372, 29804, 29370, 74113 ], "catalysts" : [ 10262445 ], "efs" : [ ], "inhibitors" : [ 10262448 ], "diagramIds" : [ 117609 ], "entityFunctionalStatus" : [ ] }, { "dbId" : 10281011, "stId" : "R-CFA-2872444", "displayName" : "SLC9B1/C2 exchange Na+ for H+", "schemaClass" : "Reaction", "speciesId" : 0, "inputs" : [ 70106, 74113 ], "outputs" : [ 351626, 83910 ], "catalysts" : [ 10281008 ], "efs" : [ ], "diagramIds" : [ 117703 ], "entityFunctionalStatus" : [ ] }, { "dbId" : 10280494, "stId" : "R-CFA-2685505", "displayName" : "TPCN1/2 transport lysosomal Ca2+ to cytosol ", "schemaClass" : "Reaction", "speciesId" : 0, "inputs" : [ 1606834 ], "outputs" : [ 74016 ], "catalysts" : [ 10280491 ], "efs" : [ ], "activators" : [ 2730676 ], "diagramIds" : [ 117676 ], "entityFunctionalStatus" : [ ] }, { "dbId" : 10280878, "stId" : "R-CFA-2752067", "displayName" : "BESTs transport cytosolic HCO3- to extracellular region", "schemaClass" : "Reaction", "speciesId" : 0, "inputs" : [ 111627 ], "outputs" : [ 425425 ], "catalysts" : [ 10280866 ], "efs" : [ ], "diagramIds" : [ 117673 ], "entityFunctionalStatus" : [ ] }, { "dbId" : 10262382, "stId" : "R-CFA-936883", "displayName" : "ATP2C1/2:Mg2+ transport cytosolic Ca2+ to Golgi lumen", "schemaClass" : "Reaction", "speciesId" : 0, "inputs" : [ 29356, 113592, 74016 ], "outputs" : [ 29372, 29370, 167012 ], "catalysts" : [ 10262379 ], "efs" : [ ], "diagramIds" : [ 117594 ], "entityFunctionalStatus" : [ ] }, { "dbId" : 10320680, "stId" : "R-CFA-9701211", "displayName" : "TRPA1 tetramer binds TRPA1 antagonists", "schemaClass" : "Reaction", "speciesId" : 0, "inputs" : [ 9701208, 10320662 ], "outputs" : [ 10320678 ], "efs" : [ ], "diagramIds" : [ 117814 ], "entityFunctionalStatus" : [ ] }, { "dbId" : 10308586, "stId" : "R-CFA-8863494", "displayName" : "ASICs bind STOML3, (STOM)", "schemaClass" : "Reaction", "speciesId" : 0, "inputs" : [ 10308582, 10280326 ], "outputs" : [ 10308584 ], "efs" : [ ], "diagramIds" : [ 117750 ], "entityFunctionalStatus" : [ ] }, { "dbId" : 10280363, "stId" : "R-CFA-2672334", "displayName" : "SCNN channels transport extracellular Na+ to cytosol", "schemaClass" : "Reaction", "speciesId" : 0, "inputs" : [ 74113 ], "outputs" : [ 83910 ], "catalysts" : [ 10280360 ], "efs" : [ ], "inhibitors" : [ 2672379 ], "diagramIds" : [ 117645 ], "entityFunctionalStatus" : [ ] }, { "dbId" : 10280939, "stId" : "R-CFA-2855020", "displayName" : "RYR tetramers transport Ca2+ from sarcoplasmic reticulum lumen to cytosol", "schemaClass" : "Reaction", "speciesId" : 0, "inputs" : [ 2855229 ], "outputs" : [ 74016 ], "catalysts" : [ 10280932 ], "efs" : [ ], "inhibitors" : [ 10228807, 10280937 ], "activators" : [ 113592, 74016, 10255349 ], "diagramIds" : [ 117692 ], "entityFunctionalStatus" : [ ] }, { "dbId" : 10280869, "stId" : "R-CFA-2744361", "displayName" : "BESTs transport cytosolic Cl- to extracellular region", "schemaClass" : "Reaction", "speciesId" : 0, "inputs" : [ 352022 ], "outputs" : [ 188972 ], "catalysts" : [ 10280866 ], "efs" : [ ], "activators" : [ 10280478, 74016 ], "diagramIds" : [ 117671 ], "entityFunctionalStatus" : [ ] }, { "dbId" : 10320676, "stId" : "R-CFA-9701147", "displayName" : "TRPV1 binds TRPV1 blockers", "schemaClass" : "Reaction", "speciesId" : 0, "inputs" : [ 10282484, 9701157 ], "outputs" : [ 10320674 ], "efs" : [ ], "diagramIds" : [ 117811 ], "entityFunctionalStatus" : [ ] }, { "dbId" : 10320231, "stId" : "R-CFA-9684068", "displayName" : "ATP1A:ATP1B:FXYD binds cardiac glycosides", "schemaClass" : "Reaction", "speciesId" : 0, "inputs" : [ 9684063, 10262445 ], "outputs" : [ 10262448 ], "efs" : [ ], "diagramIds" : [ 117800 ], "entityFunctionalStatus" : [ ] }, { "dbId" : 10319782, "stId" : "R-CFA-9659611", "displayName" : "ANO1 inhibitors bind ANO1", "schemaClass" : "Reaction", "speciesId" : 0, "inputs" : [ 9659575, 10280429 ], "outputs" : [ 10319780 ], "efs" : [ ], "diagramIds" : [ 117796 ], "entityFunctionalStatus" : [ ] }, { "dbId" : 10280480, "stId" : "R-CFA-2684901", "displayName" : "ANOs transport cytosolic Cl- to extracellular region", "schemaClass" : "Reaction", "speciesId" : 0, "inputs" : [ 352022 ], "outputs" : [ 188972 ], "catalysts" : [ 10280463 ], "efs" : [ ], "activators" : [ 10280478, 74016 ], "diagramIds" : [ 117658 ], "entityFunctionalStatus" : [ ] }, { "dbId" : 10320672, "stId" : "R-CFA-9701141", "displayName" : "TRPV1 transports Ca2+ from extracellular region to cytosol", "schemaClass" : "Reaction", "speciesId" : 0, "inputs" : [ 74112 ], "outputs" : [ 74016 ], "catalysts" : [ 10282484 ], "efs" : [ ], "diagramIds" : [ 117806 ], "entityFunctionalStatus" : [ ] }, { "dbId" : 10296416, "stId" : "R-CFA-5692480", "displayName" : "ATP13A2 transports cations from cytosol to lysosomal lumen", "schemaClass" : "Reaction", "speciesId" : 0, "inputs" : [ 29356, 113592, 5692450 ], "outputs" : [ 29372, 29370, 5692484 ], "catalysts" : [ 10296413 ], "efs" : [ ], "diagramIds" : [ 117742 ], "entityFunctionalStatus" : [ ] }, { "dbId" : 10280418, "stId" : "R-CFA-2682349", "displayName" : "RAF1:SGK:TSC22D3:WPP ubiquitinates SCNN channels", "schemaClass" : "Reaction", "speciesId" : 0, "inputs" : [ 10226816, 113592, 10280360 ], "outputs" : [ 10280385, 29370, 947590 ], "catalysts" : [ 10280403 ], "efs" : [ ], "activators" : [ 10280416 ], "diagramIds" : [ 117650 ], "entityFunctionalStatus" : [ ] }, { "dbId" : 10319650, "stId" : "R-CFA-9650165", "displayName" : "ASIC trimers bind H+", "schemaClass" : "Reaction", "speciesId" : 0, "following" : [ 10280333 ], "inputs" : [ 351626, 10319648 ], "outputs" : [ 10280326 ], "efs" : [ ], "diagramIds" : [ 117787 ], "entityFunctionalStatus" : [ ] }, { "dbId" : 10319778, "stId" : "R-CFA-9659568", "displayName" : "ANO1 transports cytosolic Cl- to extracellular region", "schemaClass" : "Reaction", "speciesId" : 0, "inputs" : [ 352022 ], "outputs" : [ 188972 ], "catalysts" : [ 10319775 ], "efs" : [ ], "activators" : [ 10280478, 74016 ], "diagramIds" : [ 117794 ], "entityFunctionalStatus" : [ ] }, { "dbId" : 10254371, "stId" : "R-CFA-418365", "displayName" : "ATP2A1-3 transport cytosolic Ca2+ to dense tubular network lumen", "schemaClass" : "Reaction", "speciesId" : 0, "inputs" : [ 427899, 74016 ], "outputs" : [ 70106, 139827 ], "catalysts" : [ 10254368 ], "efs" : [ ], "diagramIds" : [ 117589 ], "entityFunctionalStatus" : [ ] } ], "subpathways" : [ { "dbId" : 10331041, "stId" : "R-CFA-3295583", "displayName" : "TRP channels", "events" : [ 10320669, 10282509, 10320665, 10320680, 10282522, 10320676, 10320672 ] }, { "dbId" : 10330257, "stId" : "R-CFA-936837", "displayName" : "Ion transport by P-type ATPases", "events" : [ 10321791, 10262367, 10296409, 10255764, 10262389, 10254354, 10262450, 10262611, 10287251, 10262382, 10262664, 10320231, 10262535, 10296416, 10254371, 10321794 ] }, { "dbId" : 10330983, "stId" : "R-CFA-2672351", "displayName" : "Stimuli-sensing channels", "events" : [ 10319642, 10280789, 10287382, 10280528, 10280848, 10280333, 10281032, 10280841, 10280828, 10280511, 10281023, 10281018, 10281011, 10280494, 10280878, 10308586, 10280363, 10280939, 10280869, 10319782, 10280480, 10320669, 10282509, 10320665, 10320680, 10282522, 10320676, 10320672, 10280418, 10319650, 10319778 ] } ] }