{
  "dbId" : 10101229,
  "stableId" : "R-MMU-5653890",
  "displayName" : "Lactose synthesis",
  "nodes" : [ {
    "id" : 61152,
    "reactomeId" : 10057870,
    "displayName" : "B4GALT1:LALBA",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 102,
      "y" : 291
    },
    "minX" : 47,
    "maxX" : 235,
    "minY" : 274,
    "maxY" : 302,
    "prop" : {
      "x" : 47,
      "y" : 280,
      "width" : 111,
      "height" : 22
    },
    "textPosition" : {
      "x" : 51,
      "y" : 281
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 158,
          "y" : 280
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 158,
          "y" : 280
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 61155,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 161,
          "y" : 291
        },
        "to" : {
          "x" : 227,
          "y" : 291
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 231,
          "y" : 291
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 231,
          "y" : 291
        }
      }
    }, {
      "edgeId" : 61149,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 61153,
    "reactomeId" : 735682,
    "displayName" : "UDP-Gal",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 195,
      "y" : 216
    },
    "minX" : 111,
    "maxX" : 243,
    "minY" : 200,
    "maxY" : 246,
    "prop" : {
      "x" : 160,
      "y" : 201,
      "width" : 70,
      "height" : 30
    },
    "textPosition" : {
      "x" : 166,
      "y" : 205
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 225,
          "y" : 206
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 225,
          "y" : 206
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 61155,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 219,
          "y" : 234
        },
        "to" : {
          "x" : 243,
          "y" : 246
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 61149,
      "type" : "ACTIVATOR",
      "segments" : [ {
        "from" : {
          "x" : 157,
          "y" : 221
        },
        "to" : {
          "x" : 111,
          "y" : 229
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 117,
          "y" : 224
        },
        "b" : {
          "x" : 111,
          "y" : 229
        },
        "c" : {
          "x" : 119,
          "y" : 232
        },
        "type" : "ARROW",
        "empty" : true,
        "centre" : {
          "x" : 119,
          "y" : 232
        }
      }
    } ]
  }, {
    "id" : 61154,
    "reactomeId" : 5653875,
    "displayName" : "Mn2+",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 166,
      "y" : 255
    },
    "minX" : 110,
    "maxX" : 194,
    "minY" : 233,
    "maxY" : 270,
    "prop" : {
      "x" : 140,
      "y" : 240,
      "width" : 53,
      "height" : 30
    },
    "textPosition" : {
      "x" : 144,
      "y" : 244
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 188,
          "y" : 245
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 188,
          "y" : 245
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 61149,
      "type" : "ACTIVATOR",
      "segments" : [ {
        "from" : {
          "x" : 137,
          "y" : 245
        },
        "to" : {
          "x" : 110,
          "y" : 234
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 118,
          "y" : 233
        },
        "b" : {
          "x" : 110,
          "y" : 234
        },
        "c" : {
          "x" : 115,
          "y" : 240
        },
        "type" : "ARROW",
        "empty" : true,
        "centre" : {
          "x" : 115,
          "y" : 240
        }
      }
    } ]
  }, {
    "id" : 61156,
    "reactomeId" : 425969,
    "displayName" : "H+",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 191,
      "y" : 393
    },
    "minX" : 173,
    "maxX" : 243,
    "minY" : 323,
    "maxY" : 409,
    "prop" : {
      "x" : 173,
      "y" : 378,
      "width" : 36,
      "height" : 31
    },
    "textPosition" : {
      "x" : 177,
      "y" : 383
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 204,
          "y" : 383
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 204,
          "y" : 383
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 61155,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 202,
          "y" : 375
        },
        "to" : {
          "x" : 243,
          "y" : 323
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 203,
          "y" : 367
        },
        "b" : {
          "x" : 202,
          "y" : 375
        },
        "c" : {
          "x" : 209,
          "y" : 372
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 209,
          "y" : 372
        }
      }
    } ],
    "trivial" : true
  }, {
    "id" : 61157,
    "reactomeId" : 5653871,
    "displayName" : "Lac",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 242,
      "y" : 400
    },
    "minX" : 222,
    "maxX" : 264,
    "minY" : 323,
    "maxY" : 415,
    "prop" : {
      "x" : 222,
      "y" : 385,
      "width" : 41,
      "height" : 30
    },
    "textPosition" : {
      "x" : 228,
      "y" : 389
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 258,
          "y" : 390
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 258,
          "y" : 390
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 61155,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 242,
          "y" : 382
        },
        "to" : {
          "x" : 243,
          "y" : 323
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 238,
          "y" : 375
        },
        "b" : {
          "x" : 242,
          "y" : 382
        },
        "c" : {
          "x" : 246,
          "y" : 375
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 246,
          "y" : 375
        }
      }
    } ]
  }, {
    "id" : 61158,
    "reactomeId" : 205687,
    "displayName" : "UDP",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 168,
      "y" : 357
    },
    "minX" : 148,
    "maxX" : 243,
    "minY" : 323,
    "maxY" : 372,
    "prop" : {
      "x" : 148,
      "y" : 342,
      "width" : 41,
      "height" : 30
    },
    "textPosition" : {
      "x" : 151,
      "y" : 346
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 184,
          "y" : 347
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 184,
          "y" : 347
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 61155,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 192,
          "y" : 347
        },
        "to" : {
          "x" : 243,
          "y" : 323
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 197,
          "y" : 340
        },
        "b" : {
          "x" : 192,
          "y" : 347
        },
        "c" : {
          "x" : 200,
          "y" : 348
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 200,
          "y" : 348
        }
      }
    } ]
  }, {
    "id" : 61146,
    "reactomeId" : 70113,
    "displayName" : "Glc",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 242,
      "y" : 41
    },
    "minX" : 224,
    "maxX" : 262,
    "minY" : 25,
    "maxY" : 56,
    "prop" : {
      "x" : 224,
      "y" : 26,
      "width" : 37,
      "height" : 30
    },
    "textPosition" : {
      "x" : 229,
      "y" : 30
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 256,
          "y" : 31
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 256,
          "y" : 31
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 61145,
      "type" : "INPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 61147,
    "reactomeId" : 964746,
    "displayName" : "Glc",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 243,
      "y" : 138
    },
    "minX" : 225,
    "maxX" : 263,
    "minY" : 122,
    "maxY" : 246,
    "prop" : {
      "x" : 225,
      "y" : 123,
      "width" : 37,
      "height" : 30
    },
    "textPosition" : {
      "x" : 230,
      "y" : 127
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 257,
          "y" : 128
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 257,
          "y" : 128
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 61155,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 243,
          "y" : 156
        },
        "to" : {
          "x" : 243,
          "y" : 246
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 61145,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 61148,
    "reactomeId" : 10057861,
    "displayName" : "SLC2A1 tetramer",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 146,
      "y" : 85
    },
    "minX" : 89,
    "maxX" : 233,
    "minY" : 68,
    "maxY" : 96,
    "prop" : {
      "x" : 89,
      "y" : 74,
      "width" : 115,
      "height" : 22
    },
    "textPosition" : {
      "x" : 90,
      "y" : 75
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 204,
          "y" : 74
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 204,
          "y" : 74
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 61145,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 207,
          "y" : 85
        },
        "to" : {
          "x" : 225,
          "y" : 85
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 229,
          "y" : 85
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 229,
          "y" : 85
        }
      }
    } ]
  }, {
    "id" : 61150,
    "reactomeId" : 10025479,
    "displayName" : "B4GALT1",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 102,
      "y" : 157
    },
    "minX" : 69,
    "maxX" : 141,
    "minY" : 140,
    "maxY" : 197,
    "prop" : {
      "x" : 69,
      "y" : 146,
      "width" : 66,
      "height" : 22
    },
    "textPosition" : {
      "x" : 71,
      "y" : 146
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 135,
          "y" : 146
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 135,
          "y" : 146
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 61149,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 102,
          "y" : 171
        },
        "to" : {
          "x" : 102,
          "y" : 197
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 61151,
    "reactomeId" : 10057875,
    "displayName" : "LALBA",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 174,
      "y" : 162
    },
    "minX" : 102,
    "maxX" : 205,
    "minY" : 145,
    "maxY" : 227,
    "prop" : {
      "x" : 150,
      "y" : 151,
      "width" : 49,
      "height" : 22
    },
    "textPosition" : {
      "x" : 152,
      "y" : 151
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 199,
          "y" : 151
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 199,
          "y" : 151
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 61149,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 151,
          "y" : 176
        },
        "to" : {
          "x" : 102,
          "y" : 197
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 61149,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 162,
          "y" : 176
        },
        "to" : {
          "x" : 114,
          "y" : 220
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 111,
          "y" : 223
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 111,
          "y" : 223
        }
      }
    } ]
  } ],
  "edges" : [ {
    "id" : 61155,
    "reactomeId" : 10057873,
    "displayName" : "B4GALT1:LALBA transfers Gal from UDP-Gal to Glc to form Lac",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 243,
      "y" : 291
    },
    "minX" : 237,
    "maxX" : 249,
    "minY" : 246,
    "maxY" : 323,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 243,
        "y" : 246
      },
      "to" : {
        "x" : 243,
        "y" : 291
      }
    }, {
      "from" : {
        "x" : 243,
        "y" : 291
      },
      "to" : {
        "x" : 243,
        "y" : 323
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 237,
        "y" : 285
      },
      "b" : {
        "x" : 249,
        "y" : 297
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 243,
        "y" : 291
      }
    },
    "inputs" : [ {
      "id" : 61153,
      "points" : [ {
        "x" : 219,
        "y" : 234
      } ]
    }, {
      "id" : 61147,
      "points" : [ {
        "x" : 243,
        "y" : 156
      } ]
    } ],
    "outputs" : [ {
      "id" : 61156,
      "points" : [ {
        "x" : 202,
        "y" : 375
      } ]
    }, {
      "id" : 61157,
      "points" : [ {
        "x" : 242,
        "y" : 382
      } ]
    }, {
      "id" : 61158,
      "points" : [ {
        "x" : 192,
        "y" : 347
      } ]
    } ],
    "catalysts" : [ {
      "id" : 61152,
      "points" : [ {
        "x" : 161,
        "y" : 291
      } ]
    } ]
  }, {
    "id" : 61145,
    "reactomeId" : 10057864,
    "displayName" : "SLC2A1 tetramer transports Glc from cytosol to Golgi lumen",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 241,
      "y" : 85
    },
    "minX" : 235,
    "maxX" : 247,
    "minY" : 59,
    "maxY" : 120,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 241,
        "y" : 59
      },
      "to" : {
        "x" : 241,
        "y" : 85
      }
    }, {
      "from" : {
        "x" : 241,
        "y" : 85
      },
      "to" : {
        "x" : 242,
        "y" : 120
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 238,
        "y" : 113
      },
      "b" : {
        "x" : 242,
        "y" : 120
      },
      "c" : {
        "x" : 246,
        "y" : 113
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 246,
        "y" : 113
      }
    },
    "reactionShape" : {
      "a" : {
        "x" : 235,
        "y" : 79
      },
      "b" : {
        "x" : 247,
        "y" : 91
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 241,
        "y" : 85
      }
    },
    "inputs" : [ {
      "id" : 61146
    } ],
    "outputs" : [ {
      "id" : 61147
    } ],
    "catalysts" : [ {
      "id" : 61148,
      "points" : [ {
        "x" : 207,
        "y" : 85
      } ]
    } ]
  }, {
    "id" : 61149,
    "reactomeId" : 10057878,
    "displayName" : "B4GALT1 binds LALBA",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 102,
      "y" : 231
    },
    "minX" : 96,
    "maxX" : 108,
    "minY" : 197,
    "maxY" : 277,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 102,
        "y" : 197
      },
      "to" : {
        "x" : 102,
        "y" : 231
      }
    }, {
      "from" : {
        "x" : 102,
        "y" : 231
      },
      "to" : {
        "x" : 102,
        "y" : 277
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 98,
        "y" : 270
      },
      "b" : {
        "x" : 102,
        "y" : 277
      },
      "c" : {
        "x" : 106,
        "y" : 270
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 106,
        "y" : 270
      }
    },
    "reactionShape" : {
      "a" : {
        "x" : 96,
        "y" : 225
      },
      "b" : {
        "x" : 108,
        "y" : 237
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 102,
        "y" : 231
      }
    },
    "inputs" : [ {
      "id" : 61150,
      "points" : [ {
        "x" : 102,
        "y" : 171
      } ]
    }, {
      "id" : 61151,
      "points" : [ {
        "x" : 151,
        "y" : 176
      } ]
    } ],
    "outputs" : [ {
      "id" : 61152
    } ],
    "catalysts" : [ {
      "id" : 61151,
      "points" : [ {
        "x" : 162,
        "y" : 176
      } ]
    } ],
    "activators" : [ {
      "id" : 61153,
      "points" : [ {
        "x" : 157,
        "y" : 221
      } ]
    }, {
      "id" : 61154,
      "points" : [ {
        "x" : 137,
        "y" : 245
      } ]
    } ]
  } ],
  "compartments" : [ {
    "id" : 61159,
    "reactomeId" : 70101,
    "displayName" : "cytosol",
    "schemaClass" : "Compartment",
    "renderableClass" : "Compartment",
    "position" : {
      "x" : 193,
      "y" : 232
    },
    "minX" : 0,
    "maxX" : 387,
    "minY" : 0,
    "maxY" : 464,
    "prop" : {
      "x" : 0,
      "y" : 0,
      "width" : 387,
      "height" : 464
    },
    "textPosition" : {
      "x" : 21,
      "y" : 18
    },
    "insets" : {
      "x" : 10,
      "y" : 10,
      "width" : 367,
      "height" : 444
    },
    "bgColor" : {
      "r" : 250,
      "g" : 240,
      "b" : 240
    },
    "componentIds" : [ 61160, 61146 ]
  }, {
    "id" : 61160,
    "reactomeId" : 17963,
    "displayName" : "Golgi lumen",
    "schemaClass" : "Compartment",
    "renderableClass" : "Compartment",
    "position" : {
      "x" : 193,
      "y" : 260
    },
    "minX" : 97,
    "maxX" : 290,
    "minY" : 80,
    "maxY" : 440,
    "prop" : {
      "x" : 97,
      "y" : 80,
      "width" : 193,
      "height" : 360
    },
    "textPosition" : {
      "x" : 109,
      "y" : 301
    },
    "insets" : {
      "x" : 107,
      "y" : 90,
      "width" : 173,
      "height" : 340
    },
    "bgColor" : {
      "r" : 250,
      "g" : 240,
      "b" : 240
    },
    "componentIds" : [ 61145, 61147, 61148, 61149, 61150, 61151, 61152, 61153, 61154, 61155, 61158, 61157, 61156 ]
  } ],
  "notes" : [ ],
  "links" : [ ],
  "shadows" : [ ],
  "minX" : 0,
  "maxX" : 387,
  "minY" : 0,
  "maxY" : 464,
  "disease" : false
}