{
  "dbId" : 10101199,
  "stableId" : "R-MMU-5625970",
  "displayName" : "RHO GTPases activate KTN1",
  "nodes" : [ {
    "id" : 90417,
    "reactomeId" : 10056944,
    "displayName" : "RHOA,RHOG,RAC1,CDC42:GTP:KTN1",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 470,
      "y" : 186
    },
    "minX" : 370,
    "maxX" : 588,
    "minY" : 161,
    "maxY" : 219,
    "prop" : {
      "x" : 370,
      "y" : 167,
      "width" : 201,
      "height" : 39
    },
    "textPosition" : {
      "x" : 373,
      "y" : 171
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 571,
          "y" : 167
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 571,
          "y" : 167
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 90418,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 539,
          "y" : 209
        },
        "to" : {
          "x" : 588,
          "y" : 219
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 90414,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 90416,
    "reactomeId" : 10056942,
    "displayName" : "KTN1",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 270,
      "y" : 216
    },
    "minX" : 250,
    "maxX" : 329,
    "minY" : 189,
    "maxY" : 227,
    "prop" : {
      "x" : 250,
      "y" : 205,
      "width" : 41,
      "height" : 22
    },
    "textPosition" : {
      "x" : 251,
      "y" : 206
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 291,
          "y" : 205
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 291,
          "y" : 205
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 90414,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 294,
          "y" : 206
        },
        "to" : {
          "x" : 329,
          "y" : 189
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 90419,
    "reactomeId" : 10027068,
    "displayName" : "Kinesin-1",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 671,
      "y" : 165
    },
    "minX" : 588,
    "maxX" : 714,
    "minY" : 148,
    "maxY" : 219,
    "prop" : {
      "x" : 635,
      "y" : 154,
      "width" : 73,
      "height" : 22
    },
    "textPosition" : {
      "x" : 639,
      "y" : 155
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 708,
          "y" : 154
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 708,
          "y" : 154
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 90418,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 654,
          "y" : 179
        },
        "to" : {
          "x" : 588,
          "y" : 219
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 90420,
    "reactomeId" : 10059355,
    "displayName" : "RHOA,RHOG,RAC1,CDC42:GTP:KTN1:Kinesin-1",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 585,
      "y" : 272
    },
    "minX" : 488,
    "maxX" : 688,
    "minY" : 246,
    "maxY" : 293,
    "prop" : {
      "x" : 488,
      "y" : 252,
      "width" : 194,
      "height" : 41
    },
    "textPosition" : {
      "x" : 488,
      "y" : 258
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 682,
          "y" : 252
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 682,
          "y" : 252
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 90418,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 90415,
    "reactomeId" : 10056936,
    "displayName" : "RHOA,RHOG,RAC1,CDC42:GTP",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 256,
      "y" : 149
    },
    "minX" : 157,
    "maxX" : 362,
    "minY" : 131,
    "maxY" : 189,
    "prop" : {
      "x" : 157,
      "y" : 137,
      "width" : 199,
      "height" : 25
    },
    "textPosition" : {
      "x" : 161,
      "y" : 141
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 356,
          "y" : 137
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 356,
          "y" : 137
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 90414,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 278,
          "y" : 165
        },
        "to" : {
          "x" : 329,
          "y" : 189
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  } ],
  "edges" : [ {
    "id" : 90418,
    "reactomeId" : 10059357,
    "displayName" : "KTN1 binds Kinesin-1",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 588,
      "y" : 221
    },
    "minX" : 582,
    "maxX" : 594,
    "minY" : 215,
    "maxY" : 249,
    "reactionType" : "binding",
    "segments" : [ {
      "from" : {
        "x" : 588,
        "y" : 219
      },
      "to" : {
        "x" : 588,
        "y" : 221
      }
    }, {
      "from" : {
        "x" : 588,
        "y" : 221
      },
      "to" : {
        "x" : 586,
        "y" : 249
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 583,
        "y" : 242
      },
      "b" : {
        "x" : 586,
        "y" : 249
      },
      "c" : {
        "x" : 590,
        "y" : 242
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 590,
        "y" : 242
      }
    },
    "reactionShape" : {
      "c" : {
        "x" : 588,
        "y" : 221
      },
      "r" : 5,
      "type" : "CIRCLE",
      "centre" : {
        "x" : 588,
        "y" : 221
      }
    },
    "inputs" : [ {
      "id" : 90419,
      "points" : [ {
        "x" : 654,
        "y" : 179
      } ]
    }, {
      "id" : 90417,
      "points" : [ {
        "x" : 539,
        "y" : 209
      } ]
    } ],
    "outputs" : [ {
      "id" : 90420
    } ]
  }, {
    "id" : 90414,
    "reactomeId" : 10056946,
    "displayName" : "Activated RHOA, RHOG, RAC1 and CDC42 bind KTN1 (kinectin)",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 328,
      "y" : 189
    },
    "minX" : 322,
    "maxX" : 367,
    "minY" : 183,
    "maxY" : 195,
    "reactionType" : "binding",
    "segments" : [ {
      "from" : {
        "x" : 329,
        "y" : 189
      },
      "to" : {
        "x" : 328,
        "y" : 189
      }
    }, {
      "from" : {
        "x" : 328,
        "y" : 189
      },
      "to" : {
        "x" : 367,
        "y" : 188
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 360,
        "y" : 192
      },
      "b" : {
        "x" : 367,
        "y" : 188
      },
      "c" : {
        "x" : 360,
        "y" : 184
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 360,
        "y" : 184
      }
    },
    "reactionShape" : {
      "c" : {
        "x" : 328,
        "y" : 189
      },
      "r" : 5,
      "type" : "CIRCLE",
      "centre" : {
        "x" : 328,
        "y" : 189
      }
    },
    "inputs" : [ {
      "id" : 90415,
      "points" : [ {
        "x" : 278,
        "y" : 165
      } ]
    }, {
      "id" : 90416,
      "points" : [ {
        "x" : 294,
        "y" : 206
      } ]
    } ],
    "outputs" : [ {
      "id" : 90417
    } ]
  } ],
  "compartments" : [ {
    "id" : 90421,
    "reactomeId" : 70101,
    "displayName" : "cytosol",
    "schemaClass" : "Compartment",
    "renderableClass" : "Compartment",
    "position" : {
      "x" : 414,
      "y" : 231
    },
    "minX" : 0,
    "maxX" : 829,
    "minY" : 0,
    "maxY" : 462,
    "prop" : {
      "x" : 0,
      "y" : 0,
      "width" : 829,
      "height" : 462
    },
    "textPosition" : {
      "x" : 60,
      "y" : 402
    },
    "insets" : {
      "x" : 10,
      "y" : 10,
      "width" : 809,
      "height" : 442
    },
    "bgColor" : {
      "r" : 250,
      "g" : 240,
      "b" : 240
    },
    "componentIds" : [ 90422, 90418, 90419 ]
  }, {
    "id" : 90422,
    "reactomeId" : 17957,
    "displayName" : "endoplasmic reticulum lumen",
    "schemaClass" : "Compartment",
    "renderableClass" : "Compartment",
    "position" : {
      "x" : 403,
      "y" : 272
    },
    "minX" : 234,
    "maxX" : 572,
    "minY" : 137,
    "maxY" : 407,
    "prop" : {
      "x" : 234,
      "y" : 137,
      "width" : 338,
      "height" : 270
    },
    "textPosition" : {
      "x" : 255,
      "y" : 355
    },
    "insets" : {
      "x" : 244,
      "y" : 147,
      "width" : 318,
      "height" : 250
    },
    "bgColor" : {
      "r" : 250,
      "g" : 240,
      "b" : 240
    },
    "componentIds" : [ 90415, 90417, 90414, 90420, 90416 ]
  } ],
  "notes" : [ ],
  "links" : [ ],
  "shadows" : [ ],
  "minX" : 0,
  "maxX" : 829,
  "minY" : 0,
  "maxY" : 462,
  "disease" : false
}