{
  "dbId" : 10100699,
  "stableId" : "R-MMU-1461973",
  "displayName" : "Defensins",
  "nodes" : [ {
    "id" : 98496,
    "reactomeId" : 10031776,
    "displayName" : "Homologues of DEFA5(20-94)",
    "schemaClass" : "DefinedSet",
    "renderableClass" : "EntitySet",
    "position" : {
      "x" : 383,
      "y" : 93
    },
    "minX" : 334,
    "maxX" : 433,
    "minY" : 75,
    "maxY" : 112,
    "prop" : {
      "x" : 334,
      "y" : 75,
      "width" : 99,
      "height" : 37
    },
    "textPosition" : {
      "x" : 338,
      "y" : 69
    },
    "connectors" : [ {
      "edgeId" : 98497,
      "type" : "INPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 98495,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 98499,
    "reactomeId" : 10031814,
    "displayName" : "Trypsin 2, 3",
    "schemaClass" : "DefinedSet",
    "renderableClass" : "EntitySet",
    "position" : {
      "x" : 499,
      "y" : 34
    },
    "minX" : 459,
    "maxX" : 539,
    "minY" : 23,
    "maxY" : 85,
    "prop" : {
      "x" : 459,
      "y" : 23,
      "width" : 80,
      "height" : 22
    },
    "textPosition" : {
      "x" : 459,
      "y" : 23
    },
    "connectors" : [ {
      "edgeId" : 98497,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 499,
          "y" : 51
        },
        "to" : {
          "x" : 499,
          "y" : 77
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 499,
          "y" : 81
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 499,
          "y" : 81
        }
      }
    } ]
  }, {
    "id" : 98498,
    "reactomeId" : 10031658,
    "displayName" : "Homologues of DEFA5(?-94)",
    "schemaClass" : "DefinedSet",
    "renderableClass" : "EntitySet",
    "position" : {
      "x" : 588,
      "y" : 93
    },
    "minX" : 535,
    "maxX" : 642,
    "minY" : 82,
    "maxY" : 104,
    "prop" : {
      "x" : 535,
      "y" : 82,
      "width" : 107,
      "height" : 22
    },
    "textPosition" : {
      "x" : 535,
      "y" : 76
    },
    "connectors" : [ {
      "edgeId" : 98497,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 98501,
    "reactomeId" : 10032245,
    "displayName" : "Alpha-defensins",
    "schemaClass" : "DefinedSet",
    "renderableClass" : "EntitySet",
    "position" : {
      "x" : 590,
      "y" : 144
    },
    "minX" : 536,
    "maxX" : 672,
    "minY" : 133,
    "maxY" : 155,
    "prop" : {
      "x" : 536,
      "y" : 133,
      "width" : 109,
      "height" : 22
    },
    "textPosition" : {
      "x" : 536,
      "y" : 133
    },
    "connectors" : [ {
      "edgeId" : 98500,
      "type" : "INPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 2,
        "shape" : {
          "a" : {
            "x" : 660,
            "y" : 137
          },
          "b" : {
            "x" : 672,
            "y" : 149
          },
          "type" : "BOX",
          "empty" : true,
          "centre" : {
            "x" : 666,
            "y" : 143
          }
        }
      }
    } ]
  }, {
    "id" : 98502,
    "reactomeId" : 10031716,
    "displayName" : "Alpha-defensin dimers",
    "schemaClass" : "DefinedSet",
    "renderableClass" : "EntitySet",
    "position" : {
      "x" : 766,
      "y" : 145
    },
    "minX" : 714,
    "maxX" : 818,
    "minY" : 127,
    "maxY" : 252,
    "prop" : {
      "x" : 714,
      "y" : 127,
      "width" : 104,
      "height" : 36
    },
    "textPosition" : {
      "x" : 714,
      "y" : 127
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "connectors" : [ {
      "edgeId" : 98500,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 98503,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 768,
          "y" : 169
        },
        "to" : {
          "x" : 783,
          "y" : 252
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "isDisease" : true
    } ]
  }, {
    "id" : 98505,
    "reactomeId" : 10031718,
    "displayName" : "Alpha-defensin dimers:anionic phospholipids",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 928,
      "y" : 299
    },
    "minX" : 876,
    "maxX" : 986,
    "minY" : 268,
    "maxY" : 364,
    "prop" : {
      "x" : 876,
      "y" : 274,
      "width" : 104,
      "height" : 50
    },
    "textPosition" : {
      "x" : 876,
      "y" : 275
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "fgColor" : {
      "r" : 0,
      "g" : 0,
      "b" : 0
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 980,
          "y" : 274
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 980,
          "y" : 274
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 98503,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      },
      "isDisease" : true
    }, {
      "edgeId" : 98506,
      "type" : "INPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 6,
        "shape" : {
          "a" : {
            "x" : 922,
            "y" : 352
          },
          "b" : {
            "x" : 934,
            "y" : 364
          },
          "type" : "BOX",
          "empty" : true,
          "centre" : {
            "x" : 928,
            "y" : 358
          }
        }
      },
      "isDisease" : true
    } ]
  }, {
    "id" : 98504,
    "reactomeId" : 1462049,
    "displayName" : "Anionic phospholipids",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 755,
      "y" : 291
    },
    "minX" : 707,
    "maxX" : 804,
    "minY" : 252,
    "maxY" : 438,
    "prop" : {
      "x" : 707,
      "y" : 273,
      "width" : 96,
      "height" : 36
    },
    "textPosition" : {
      "x" : 707,
      "y" : 273
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "fgColor" : {
      "r" : 0,
      "g" : 0,
      "b" : 0
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 798,
          "y" : 278
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 798,
          "y" : 278
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 98503,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 767,
          "y" : 270
        },
        "to" : {
          "x" : 783,
          "y" : 252
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "isDisease" : true
    }, {
      "edgeId" : 98515,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 754,
          "y" : 312
        },
        "to" : {
          "x" : 754,
          "y" : 438
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "isDisease" : true
    } ]
  }, {
    "id" : 98507,
    "reactomeId" : 10031722,
    "displayName" : "Alpha-defensin pore complex",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 930,
      "y" : 495
    },
    "minX" : 879,
    "maxX" : 988,
    "minY" : 471,
    "maxY" : 514,
    "prop" : {
      "x" : 879,
      "y" : 477,
      "width" : 103,
      "height" : 37
    },
    "textPosition" : {
      "x" : 878,
      "y" : 479
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "fgColor" : {
      "r" : 0,
      "g" : 0,
      "b" : 0
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 982,
          "y" : 477
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 982,
          "y" : 477
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 98506,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      },
      "isDisease" : true
    } ]
  }, {
    "id" : 98509,
    "reactomeId" : 10004217,
    "displayName" : "Cd4",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 211,
      "y" : 283
    },
    "minX" : 194,
    "maxX" : 234,
    "minY" : 224,
    "maxY" : 294,
    "prop" : {
      "x" : 194,
      "y" : 272,
      "width" : 34,
      "height" : 22
    },
    "textPosition" : {
      "x" : 195,
      "y" : 272
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 228,
          "y" : 272
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 228,
          "y" : 272
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 98508,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 213,
          "y" : 269
        },
        "to" : {
          "x" : 227,
          "y" : 224
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 98511,
    "reactomeId" : 10032853,
    "displayName" : "Defensins alpha 1-3:CD4",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 307,
      "y" : 280
    },
    "minX" : 258,
    "maxX" : 362,
    "minY" : 256,
    "maxY" : 298,
    "prop" : {
      "x" : 258,
      "y" : 262,
      "width" : 98,
      "height" : 36
    },
    "textPosition" : {
      "x" : 259,
      "y" : 263
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 356,
          "y" : 262
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 356,
          "y" : 262
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 98508,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 98510,
    "reactomeId" : 10032851,
    "displayName" : "Defensins alpha 1-3",
    "schemaClass" : "DefinedSet",
    "renderableClass" : "EntitySet",
    "position" : {
      "x" : 96,
      "y" : 153
    },
    "minX" : 57,
    "maxX" : 227,
    "minY" : 137,
    "maxY" : 224,
    "prop" : {
      "x" : 57,
      "y" : 137,
      "width" : 78,
      "height" : 32
    },
    "textPosition" : {
      "x" : 59,
      "y" : 136
    },
    "connectors" : [ {
      "edgeId" : 98508,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 125,
          "y" : 175
        },
        "to" : {
          "x" : 227,
          "y" : 224
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 98513,
    "reactomeId" : 10032859,
    "displayName" : "Beta-defensins",
    "schemaClass" : "CandidateSet",
    "renderableClass" : "EntitySet",
    "position" : {
      "x" : 365,
      "y" : 620
    },
    "minX" : 314,
    "maxX" : 417,
    "minY" : 609,
    "maxY" : 631,
    "prop" : {
      "x" : 314,
      "y" : 609,
      "width" : 103,
      "height" : 22
    },
    "textPosition" : {
      "x" : 314,
      "y" : 609
    },
    "connectors" : [ {
      "edgeId" : 98512,
      "type" : "INPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 98514,
    "reactomeId" : 10032801,
    "displayName" : "Beta-defensins",
    "schemaClass" : "CandidateSet",
    "renderableClass" : "EntitySet",
    "position" : {
      "x" : 691,
      "y" : 619
    },
    "minX" : 640,
    "maxX" : 754,
    "minY" : 438,
    "maxY" : 630,
    "prop" : {
      "x" : 640,
      "y" : 608,
      "width" : 103,
      "height" : 22
    },
    "textPosition" : {
      "x" : 640,
      "y" : 608
    },
    "connectors" : [ {
      "edgeId" : 98512,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 98515,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 694,
          "y" : 602
        },
        "to" : {
          "x" : 754,
          "y" : 438
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "isDisease" : true
    } ]
  }, {
    "id" : 98516,
    "reactomeId" : 10032803,
    "displayName" : "Beta-defensins:anionic phospholipids",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 818,
      "y" : 495
    },
    "minX" : 765,
    "maxX" : 878,
    "minY" : 464,
    "maxY" : 520,
    "prop" : {
      "x" : 765,
      "y" : 470,
      "width" : 107,
      "height" : 50
    },
    "textPosition" : {
      "x" : 765,
      "y" : 471
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "fgColor" : {
      "r" : 0,
      "g" : 0,
      "b" : 0
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 872,
          "y" : 470
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 872,
          "y" : 470
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 98515,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      },
      "isDisease" : true
    } ]
  }, {
    "id" : 98519,
    "reactomeId" : 10008604,
    "displayName" : "Ccr6",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 277,
      "y" : 742
    },
    "minX" : 256,
    "maxX" : 313,
    "minY" : 725,
    "maxY" : 785,
    "prop" : {
      "x" : 256,
      "y" : 731,
      "width" : 42,
      "height" : 22
    },
    "textPosition" : {
      "x" : 259,
      "y" : 731
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 298,
          "y" : 731
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 298,
          "y" : 731
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 98517,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 286,
          "y" : 756
        },
        "to" : {
          "x" : 313,
          "y" : 785
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 98518,
    "reactomeId" : 10032863,
    "displayName" : "Beta defensins 1,4A,103",
    "schemaClass" : "DefinedSet",
    "renderableClass" : "EntitySet",
    "position" : {
      "x" : 263,
      "y" : 841
    },
    "minX" : 221,
    "maxX" : 313,
    "minY" : 785,
    "maxY" : 867,
    "prop" : {
      "x" : 221,
      "y" : 816,
      "width" : 85,
      "height" : 51
    },
    "textPosition" : {
      "x" : 227,
      "y" : 817
    },
    "connectors" : [ {
      "edgeId" : 98517,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 285,
          "y" : 810
        },
        "to" : {
          "x" : 313,
          "y" : 785
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 98520,
    "reactomeId" : 10032865,
    "displayName" : "Beta-defensins 1,4A,103:CCR6",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 446,
      "y" : 742
    },
    "minX" : 389,
    "maxX" : 509,
    "minY" : 718,
    "maxY" : 760,
    "prop" : {
      "x" : 389,
      "y" : 724,
      "width" : 114,
      "height" : 36
    },
    "textPosition" : {
      "x" : 393,
      "y" : 725
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 503,
          "y" : 724
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 503,
          "y" : 724
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 98517,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 98523,
    "reactomeId" : 10037839,
    "displayName" : "Homologues of omega-N-(ADP-ribosyl)-L-arginine-DEFA1(65-94)",
    "schemaClass" : "DefinedSet",
    "renderableClass" : "EntitySet",
    "position" : {
      "x" : 662,
      "y" : 208
    },
    "minX" : 604,
    "maxX" : 720,
    "minY" : 177,
    "maxY" : 239,
    "prop" : {
      "x" : 604,
      "y" : 177,
      "width" : 116,
      "height" : 62
    },
    "textPosition" : {
      "x" : 609,
      "y" : 170
    },
    "connectors" : [ {
      "edgeId" : 98521,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 98522,
    "reactomeId" : 10031496,
    "displayName" : "Homologues of DEFA1(65-94)",
    "schemaClass" : "DefinedSet",
    "renderableClass" : "EntitySet",
    "position" : {
      "x" : 448,
      "y" : 210
    },
    "minX" : 395,
    "maxX" : 502,
    "minY" : 199,
    "maxY" : 221,
    "prop" : {
      "x" : 395,
      "y" : 199,
      "width" : 107,
      "height" : 22
    },
    "textPosition" : {
      "x" : 395,
      "y" : 193
    },
    "connectors" : [ {
      "edgeId" : 98521,
      "type" : "INPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 98524,
    "reactomeId" : 10037843,
    "displayName" : "ART1",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 468,
      "y" : 279
    },
    "minX" : 448,
    "maxX" : 532,
    "minY" : 214,
    "maxY" : 290,
    "prop" : {
      "x" : 448,
      "y" : 268,
      "width" : 41,
      "height" : 22
    },
    "textPosition" : {
      "x" : 449,
      "y" : 268
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 489,
          "y" : 268
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 489,
          "y" : 268
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 98521,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 484,
          "y" : 265
        },
        "to" : {
          "x" : 528,
          "y" : 240
        }
      }, {
        "from" : {
          "x" : 528,
          "y" : 240
        },
        "to" : {
          "x" : 528,
          "y" : 222
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 528,
          "y" : 218
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 528,
          "y" : 218
        }
      }
    } ]
  }, {
    "id" : 98527,
    "reactomeId" : 10032767,
    "displayName" : "Defb14",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 599,
      "y" : 438
    },
    "minX" : 566,
    "maxX" : 635,
    "minY" : 409,
    "maxY" : 475,
    "prop" : {
      "x" : 570,
      "y" : 415,
      "width" : 59,
      "height" : 46
    },
    "textPosition" : {
      "x" : 573,
      "y" : 427
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 629,
          "y" : 415
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 629,
          "y" : 415
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 98525,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 578,
          "y" : 464
        },
        "to" : {
          "x" : 566,
          "y" : 475
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 98526,
    "reactomeId" : 10037862,
    "displayName" : "TLR1:TLR2",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 534,
      "y" : 436
    },
    "minX" : 508,
    "maxX" : 567,
    "minY" : 413,
    "maxY" : 475,
    "prop" : {
      "x" : 508,
      "y" : 419,
      "width" : 53,
      "height" : 34
    },
    "textPosition" : {
      "x" : 514,
      "y" : 418
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 561,
          "y" : 419
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 561,
          "y" : 419
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 98525,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 547,
          "y" : 456
        },
        "to" : {
          "x" : 566,
          "y" : 475
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 98528,
    "reactomeId" : 10037864,
    "displayName" : "Beta defensin 103:TLR1:TLR2",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 543,
      "y" : 590
    },
    "minX" : 492,
    "maxX" : 601,
    "minY" : 566,
    "maxY" : 608,
    "prop" : {
      "x" : 492,
      "y" : 572,
      "width" : 103,
      "height" : 36
    },
    "textPosition" : {
      "x" : 494,
      "y" : 573
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 595,
          "y" : 572
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 595,
          "y" : 572
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 98525,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 98537,
    "reactomeId" : 10037852,
    "displayName" : "Beta defensins 4A,103",
    "schemaClass" : "DefinedSet",
    "renderableClass" : "EntitySet",
    "position" : {
      "x" : 57,
      "y" : 840
    },
    "minX" : 0,
    "maxX" : 115,
    "minY" : 822,
    "maxY" : 858,
    "prop" : {
      "x" : 0,
      "y" : 822,
      "width" : 115,
      "height" : 36
    },
    "textPosition" : {
      "x" : 4,
      "y" : 822
    },
    "connectors" : [ ]
  }, {
    "id" : 98483,
    "reactomeId" : 10032597,
    "displayName" : "Pro-defensins",
    "schemaClass" : "CandidateSet",
    "renderableClass" : "EntitySet",
    "position" : {
      "x" : 263,
      "y" : 533
    },
    "minX" : 216,
    "maxX" : 311,
    "minY" : 522,
    "maxY" : 544,
    "prop" : {
      "x" : 216,
      "y" : 522,
      "width" : 95,
      "height" : 22
    },
    "textPosition" : {
      "x" : 216,
      "y" : 522
    },
    "connectors" : [ {
      "edgeId" : 98481,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 98482,
    "reactomeId" : 10032463,
    "displayName" : "Pre-pro-defensins",
    "schemaClass" : "CandidateSet",
    "renderableClass" : "EntitySet",
    "position" : {
      "x" : 263,
      "y" : 656
    },
    "minX" : 203,
    "maxX" : 323,
    "minY" : 645,
    "maxY" : 667,
    "prop" : {
      "x" : 203,
      "y" : 645,
      "width" : 120,
      "height" : 22
    },
    "textPosition" : {
      "x" : 203,
      "y" : 645
    },
    "connectors" : [ {
      "edgeId" : 98481,
      "type" : "INPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 98485,
    "reactomeId" : 10032601,
    "displayName" : "Pro-defensins alpha 1-4",
    "schemaClass" : "CandidateSet",
    "renderableClass" : "EntitySet",
    "position" : {
      "x" : 101,
      "y" : 649
    },
    "minX" : 56,
    "maxX" : 146,
    "minY" : 628,
    "maxY" : 671,
    "prop" : {
      "x" : 56,
      "y" : 628,
      "width" : 90,
      "height" : 43
    },
    "textPosition" : {
      "x" : 64,
      "y" : 625
    },
    "connectors" : [ {
      "edgeId" : 98484,
      "type" : "INPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 98487,
    "reactomeId" : 10032759,
    "displayName" : "Pro-defensin fragments",
    "schemaClass" : "CandidateSet",
    "renderableClass" : "EntitySet",
    "position" : {
      "x" : 180,
      "y" : 577
    },
    "minX" : 100,
    "maxX" : 224,
    "minY" : 559,
    "maxY" : 595,
    "prop" : {
      "x" : 136,
      "y" : 559,
      "width" : 88,
      "height" : 36
    },
    "textPosition" : {
      "x" : 135,
      "y" : 559
    },
    "connectors" : [ {
      "edgeId" : 98484,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 130,
          "y" : 576
        },
        "to" : {
          "x" : 100,
          "y" : 576
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 123,
          "y" : 580
        },
        "b" : {
          "x" : 130,
          "y" : 576
        },
        "c" : {
          "x" : 123,
          "y" : 572
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 123,
          "y" : 572
        }
      }
    } ]
  }, {
    "id" : 98486,
    "reactomeId" : 10032081,
    "displayName" : "Defensins alpha 1-4",
    "schemaClass" : "CandidateSet",
    "renderableClass" : "EntitySet",
    "position" : {
      "x" : 100,
      "y" : 534
    },
    "minX" : 56,
    "maxX" : 145,
    "minY" : 515,
    "maxY" : 576,
    "prop" : {
      "x" : 56,
      "y" : 515,
      "width" : 89,
      "height" : 38
    },
    "textPosition" : {
      "x" : 63,
      "y" : 516
    },
    "connectors" : [ {
      "edgeId" : 98484,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 100,
          "y" : 559
        },
        "to" : {
          "x" : 100,
          "y" : 576
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 104,
          "y" : 566
        },
        "b" : {
          "x" : 100,
          "y" : 559
        },
        "c" : {
          "x" : 96,
          "y" : 566
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 96,
          "y" : 566
        }
      }
    }, {
      "edgeId" : 98488,
      "type" : "INPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 98489,
    "reactomeId" : 10032239,
    "displayName" : "Defensins alpha 1-4",
    "schemaClass" : "CandidateSet",
    "renderableClass" : "EntitySet",
    "position" : {
      "x" : 101,
      "y" : 347
    },
    "minX" : 58,
    "maxX" : 144,
    "minY" : 329,
    "maxY" : 365,
    "prop" : {
      "x" : 58,
      "y" : 329,
      "width" : 86,
      "height" : 36
    },
    "textPosition" : {
      "x" : 64,
      "y" : 329
    },
    "connectors" : [ {
      "edgeId" : 98488,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 98490,
      "type" : "INPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 98491,
    "reactomeId" : 10032763,
    "displayName" : "Defensins alpha 1-4",
    "schemaClass" : "CandidateSet",
    "renderableClass" : "EntitySet",
    "position" : {
      "x" : 101,
      "y" : 209
    },
    "minX" : 57,
    "maxX" : 145,
    "minY" : 192,
    "maxY" : 226,
    "prop" : {
      "x" : 57,
      "y" : 192,
      "width" : 88,
      "height" : 34
    },
    "textPosition" : {
      "x" : 64,
      "y" : 192
    },
    "connectors" : [ {
      "edgeId" : 98490,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 98493,
    "reactomeId" : 10031869,
    "displayName" : "Homologues of DEFA5(20-94)",
    "schemaClass" : "DefinedSet",
    "renderableClass" : "EntitySet",
    "position" : {
      "x" : 382,
      "y" : 538
    },
    "minX" : 341,
    "maxX" : 424,
    "minY" : 517,
    "maxY" : 559,
    "prop" : {
      "x" : 341,
      "y" : 517,
      "width" : 83,
      "height" : 42
    },
    "textPosition" : {
      "x" : 343,
      "y" : 514
    },
    "connectors" : [ {
      "edgeId" : 98492,
      "type" : "INPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 98494,
    "reactomeId" : 10031921,
    "displayName" : "Homologues of DEFA5(20-94)",
    "schemaClass" : "DefinedSet",
    "renderableClass" : "EntitySet",
    "position" : {
      "x" : 383,
      "y" : 408
    },
    "minX" : 341,
    "maxX" : 425,
    "minY" : 388,
    "maxY" : 428,
    "prop" : {
      "x" : 341,
      "y" : 388,
      "width" : 84,
      "height" : 40
    },
    "textPosition" : {
      "x" : 343,
      "y" : 384
    },
    "connectors" : [ {
      "edgeId" : 98492,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 98495,
      "type" : "INPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  } ],
  "edges" : [ {
    "id" : 98497,
    "reactomeId" : 10031817,
    "displayName" : "pro-HD5 is cleaved by trypsin",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 499,
      "y" : 93
    },
    "minX" : 436,
    "maxX" : 532,
    "minY" : 87,
    "maxY" : 99,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 436,
        "y" : 93
      },
      "to" : {
        "x" : 499,
        "y" : 93
      }
    }, {
      "from" : {
        "x" : 499,
        "y" : 93
      },
      "to" : {
        "x" : 532,
        "y" : 93
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 525,
        "y" : 97
      },
      "b" : {
        "x" : 532,
        "y" : 93
      },
      "c" : {
        "x" : 525,
        "y" : 89
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 525,
        "y" : 89
      }
    },
    "reactionShape" : {
      "a" : {
        "x" : 493,
        "y" : 87
      },
      "b" : {
        "x" : 505,
        "y" : 99
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 499,
        "y" : 93
      }
    },
    "inputs" : [ {
      "id" : 98496
    } ],
    "outputs" : [ {
      "id" : 98498
    } ],
    "catalysts" : [ {
      "id" : 98499,
      "points" : [ {
        "x" : 499,
        "y" : 51
      } ]
    } ]
  }, {
    "id" : 98500,
    "reactomeId" : 10032247,
    "displayName" : "Alpha-defensins form biologically active dimers",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 682,
      "y" : 143
    },
    "minX" : 651,
    "maxX" : 708,
    "minY" : 137,
    "maxY" : 149,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 651,
        "y" : 143
      },
      "to" : {
        "x" : 682,
        "y" : 143
      }
    }, {
      "from" : {
        "x" : 682,
        "y" : 143
      },
      "to" : {
        "x" : 708,
        "y" : 143
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 701,
        "y" : 147
      },
      "b" : {
        "x" : 708,
        "y" : 143
      },
      "c" : {
        "x" : 701,
        "y" : 139
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 701,
        "y" : 139
      }
    },
    "reactionShape" : {
      "a" : {
        "x" : 676,
        "y" : 137
      },
      "b" : {
        "x" : 688,
        "y" : 149
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 682,
        "y" : 143
      }
    },
    "inputs" : [ {
      "id" : 98501,
      "stoichiometry" : 2
    } ],
    "outputs" : [ {
      "id" : 98502
    } ]
  }, {
    "id" : 98503,
    "reactomeId" : 10031720,
    "displayName" : "Alpha-defensin dimers adsorb onto microbial membrane anionic phospholipids",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 832,
      "y" : 253
    },
    "isDisease" : true,
    "minX" : 783,
    "maxX" : 873,
    "minY" : 247,
    "maxY" : 274,
    "reactionType" : "binding",
    "segments" : [ {
      "from" : {
        "x" : 783,
        "y" : 252
      },
      "to" : {
        "x" : 832,
        "y" : 253
      }
    }, {
      "from" : {
        "x" : 832,
        "y" : 253
      },
      "to" : {
        "x" : 873,
        "y" : 274
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 865,
        "y" : 274
      },
      "b" : {
        "x" : 873,
        "y" : 274
      },
      "c" : {
        "x" : 869,
        "y" : 267
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 869,
        "y" : 267
      }
    },
    "reactionShape" : {
      "c" : {
        "x" : 832,
        "y" : 253
      },
      "r" : 5,
      "type" : "CIRCLE",
      "centre" : {
        "x" : 832,
        "y" : 253
      }
    },
    "inputs" : [ {
      "id" : 98502,
      "points" : [ {
        "x" : 768,
        "y" : 169
      } ]
    }, {
      "id" : 98504,
      "points" : [ {
        "x" : 767,
        "y" : 270
      } ]
    } ],
    "outputs" : [ {
      "id" : 98505
    } ]
  }, {
    "id" : 98506,
    "reactomeId" : 10031724,
    "displayName" : "Alpha-defensin dimers multimerize to form a pore complex",
    "schemaClass" : "BlackBoxEvent",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 928,
      "y" : 390
    },
    "isDisease" : true,
    "minX" : 922,
    "maxX" : 934,
    "minY" : 327,
    "maxY" : 474,
    "reactionType" : "omitted",
    "segments" : [ {
      "from" : {
        "x" : 928,
        "y" : 327
      },
      "to" : {
        "x" : 928,
        "y" : 390
      }
    }, {
      "from" : {
        "x" : 928,
        "y" : 390
      },
      "to" : {
        "x" : 929,
        "y" : 474
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 925,
        "y" : 467
      },
      "b" : {
        "x" : 929,
        "y" : 474
      },
      "c" : {
        "x" : 933,
        "y" : 467
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 933,
        "y" : 467
      }
    },
    "reactionShape" : {
      "a" : {
        "x" : 922,
        "y" : 384
      },
      "b" : {
        "x" : 934,
        "y" : 396
      },
      "s" : "\\\\",
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 928,
        "y" : 390
      }
    },
    "inputs" : [ {
      "id" : 98505,
      "stoichiometry" : 6
    } ],
    "outputs" : [ {
      "id" : 98507
    } ]
  }, {
    "id" : 98508,
    "reactomeId" : 10032855,
    "displayName" : "HNP1-3 bind CD4",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 262,
      "y" : 225
    },
    "minX" : 227,
    "maxX" : 292,
    "minY" : 219,
    "maxY" : 259,
    "reactionType" : "binding",
    "segments" : [ {
      "from" : {
        "x" : 227,
        "y" : 224
      },
      "to" : {
        "x" : 262,
        "y" : 225
      }
    }, {
      "from" : {
        "x" : 262,
        "y" : 225
      },
      "to" : {
        "x" : 292,
        "y" : 259
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 284,
        "y" : 256
      },
      "b" : {
        "x" : 292,
        "y" : 259
      },
      "c" : {
        "x" : 290,
        "y" : 251
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 290,
        "y" : 251
      }
    },
    "reactionShape" : {
      "c" : {
        "x" : 262,
        "y" : 225
      },
      "r" : 5,
      "type" : "CIRCLE",
      "centre" : {
        "x" : 262,
        "y" : 225
      }
    },
    "inputs" : [ {
      "id" : 98509,
      "points" : [ {
        "x" : 213,
        "y" : 269
      } ]
    }, {
      "id" : 98510,
      "points" : [ {
        "x" : 125,
        "y" : 175
      } ]
    } ],
    "outputs" : [ {
      "id" : 98511
    } ]
  }, {
    "id" : 98481,
    "reactomeId" : 10032599,
    "displayName" : "Pre-pro-defensins are cleaved to remove the signal peptide",
    "schemaClass" : "BlackBoxEvent",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 263,
      "y" : 583
    },
    "minX" : 257,
    "maxX" : 269,
    "minY" : 550,
    "maxY" : 639,
    "reactionType" : "omitted",
    "segments" : [ {
      "from" : {
        "x" : 263,
        "y" : 639
      },
      "to" : {
        "x" : 263,
        "y" : 583
      }
    }, {
      "from" : {
        "x" : 263,
        "y" : 583
      },
      "to" : {
        "x" : 263,
        "y" : 550
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 267,
        "y" : 557
      },
      "b" : {
        "x" : 263,
        "y" : 550
      },
      "c" : {
        "x" : 259,
        "y" : 557
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 259,
        "y" : 557
      }
    },
    "reactionShape" : {
      "a" : {
        "x" : 257,
        "y" : 577
      },
      "b" : {
        "x" : 269,
        "y" : 589
      },
      "s" : "\\\\",
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 263,
        "y" : 583
      }
    },
    "inputs" : [ {
      "id" : 98482
    } ],
    "outputs" : [ {
      "id" : 98483
    } ]
  }, {
    "id" : 98512,
    "reactomeId" : 10032861,
    "displayName" : "Beta-defensins are secreted",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 490,
      "y" : 620
    },
    "minX" : 423,
    "maxX" : 634,
    "minY" : 614,
    "maxY" : 626,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 423,
        "y" : 620
      },
      "to" : {
        "x" : 490,
        "y" : 620
      }
    }, {
      "from" : {
        "x" : 490,
        "y" : 620
      },
      "to" : {
        "x" : 634,
        "y" : 619
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 627,
        "y" : 623
      },
      "b" : {
        "x" : 634,
        "y" : 619
      },
      "c" : {
        "x" : 627,
        "y" : 615
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 627,
        "y" : 615
      }
    },
    "reactionShape" : {
      "a" : {
        "x" : 484,
        "y" : 614
      },
      "b" : {
        "x" : 496,
        "y" : 626
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 490,
        "y" : 620
      }
    },
    "inputs" : [ {
      "id" : 98513
    } ],
    "outputs" : [ {
      "id" : 98514
    } ]
  }, {
    "id" : 98515,
    "reactomeId" : 10032805,
    "displayName" : "Beta-defensins bind microbial membranes causing disruption",
    "schemaClass" : "BlackBoxEvent",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 788,
      "y" : 437
    },
    "isDisease" : true,
    "minX" : 754,
    "maxX" : 805,
    "minY" : 431,
    "maxY" : 467,
    "reactionType" : "omitted",
    "segments" : [ {
      "from" : {
        "x" : 754,
        "y" : 438
      },
      "to" : {
        "x" : 788,
        "y" : 437
      }
    }, {
      "from" : {
        "x" : 788,
        "y" : 437
      },
      "to" : {
        "x" : 805,
        "y" : 467
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 798,
        "y" : 463
      },
      "b" : {
        "x" : 805,
        "y" : 467
      },
      "c" : {
        "x" : 805,
        "y" : 459
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 805,
        "y" : 459
      }
    },
    "reactionShape" : {
      "a" : {
        "x" : 782,
        "y" : 431
      },
      "b" : {
        "x" : 794,
        "y" : 443
      },
      "s" : "\\\\",
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 788,
        "y" : 437
      }
    },
    "inputs" : [ {
      "id" : 98514,
      "points" : [ {
        "x" : 694,
        "y" : 602
      } ]
    }, {
      "id" : 98504,
      "points" : [ {
        "x" : 754,
        "y" : 312
      } ]
    } ],
    "outputs" : [ {
      "id" : 98516
    } ]
  }, {
    "id" : 98517,
    "reactomeId" : 10032867,
    "displayName" : "Beta-defensins 1, 4A and 103 bind CCR6",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 347,
      "y" : 785
    },
    "minX" : 313,
    "maxX" : 404,
    "minY" : 763,
    "maxY" : 791,
    "reactionType" : "binding",
    "segments" : [ {
      "from" : {
        "x" : 313,
        "y" : 785
      },
      "to" : {
        "x" : 347,
        "y" : 785
      }
    }, {
      "from" : {
        "x" : 347,
        "y" : 785
      },
      "to" : {
        "x" : 404,
        "y" : 763
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 399,
        "y" : 769
      },
      "b" : {
        "x" : 404,
        "y" : 763
      },
      "c" : {
        "x" : 396,
        "y" : 762
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 396,
        "y" : 762
      }
    },
    "reactionShape" : {
      "c" : {
        "x" : 347,
        "y" : 785
      },
      "r" : 5,
      "type" : "CIRCLE",
      "centre" : {
        "x" : 347,
        "y" : 785
      }
    },
    "inputs" : [ {
      "id" : 98518,
      "points" : [ {
        "x" : 285,
        "y" : 810
      } ]
    }, {
      "id" : 98519,
      "points" : [ {
        "x" : 286,
        "y" : 756
      } ]
    } ],
    "outputs" : [ {
      "id" : 98520
    } ]
  }, {
    "id" : 98484,
    "reactomeId" : 10032761,
    "displayName" : "Pro-HNP1-4 are cleaved to biologically active defensin",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 99,
      "y" : 601
    },
    "minX" : 93,
    "maxX" : 105,
    "minY" : 576,
    "maxY" : 622,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 100,
        "y" : 622
      },
      "to" : {
        "x" : 99,
        "y" : 601
      }
    }, {
      "from" : {
        "x" : 99,
        "y" : 601
      },
      "to" : {
        "x" : 100,
        "y" : 576
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 93,
        "y" : 595
      },
      "b" : {
        "x" : 105,
        "y" : 607
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 99,
        "y" : 601
      }
    },
    "inputs" : [ {
      "id" : 98485
    } ],
    "outputs" : [ {
      "id" : 98486,
      "points" : [ {
        "x" : 100,
        "y" : 559
      } ]
    }, {
      "id" : 98487,
      "points" : [ {
        "x" : 130,
        "y" : 576
      } ]
    } ]
  }, {
    "id" : 98521,
    "reactomeId" : 10037846,
    "displayName" : "ADP-Ribosylation of HNP-1",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 528,
      "y" : 206
    },
    "minX" : 505,
    "maxX" : 601,
    "minY" : 200,
    "maxY" : 212,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 505,
        "y" : 207
      },
      "to" : {
        "x" : 528,
        "y" : 206
      }
    }, {
      "from" : {
        "x" : 528,
        "y" : 206
      },
      "to" : {
        "x" : 601,
        "y" : 207
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 594,
        "y" : 211
      },
      "b" : {
        "x" : 601,
        "y" : 207
      },
      "c" : {
        "x" : 594,
        "y" : 203
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 594,
        "y" : 203
      }
    },
    "reactionShape" : {
      "a" : {
        "x" : 522,
        "y" : 200
      },
      "b" : {
        "x" : 534,
        "y" : 212
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 528,
        "y" : 206
      }
    },
    "inputs" : [ {
      "id" : 98522
    } ],
    "outputs" : [ {
      "id" : 98523
    } ],
    "catalysts" : [ {
      "id" : 98524,
      "points" : [ {
        "x" : 484,
        "y" : 265
      }, {
        "x" : 528,
        "y" : 240
      } ]
    } ]
  }, {
    "id" : 98488,
    "reactomeId" : 10032241,
    "displayName" : "HNP1-4 are stored in primary neutrophil granules",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 100,
      "y" : 461
    },
    "minX" : 94,
    "maxX" : 106,
    "minY" : 371,
    "maxY" : 509,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 100,
        "y" : 509
      },
      "to" : {
        "x" : 100,
        "y" : 461
      }
    }, {
      "from" : {
        "x" : 100,
        "y" : 461
      },
      "to" : {
        "x" : 100,
        "y" : 371
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 104,
        "y" : 378
      },
      "b" : {
        "x" : 100,
        "y" : 371
      },
      "c" : {
        "x" : 96,
        "y" : 378
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 96,
        "y" : 378
      }
    },
    "reactionShape" : {
      "a" : {
        "x" : 94,
        "y" : 455
      },
      "b" : {
        "x" : 106,
        "y" : 467
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 100,
        "y" : 461
      }
    },
    "inputs" : [ {
      "id" : 98486
    } ],
    "outputs" : [ {
      "id" : 98489
    } ]
  }, {
    "id" : 98490,
    "reactomeId" : 10032765,
    "displayName" : "HNP1-4 are released into phagocytic vacuoles",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 100,
      "y" : 261
    },
    "minX" : 94,
    "maxX" : 106,
    "minY" : 232,
    "maxY" : 323,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 100,
        "y" : 323
      },
      "to" : {
        "x" : 100,
        "y" : 261
      }
    }, {
      "from" : {
        "x" : 100,
        "y" : 261
      },
      "to" : {
        "x" : 100,
        "y" : 232
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 104,
        "y" : 239
      },
      "b" : {
        "x" : 100,
        "y" : 232
      },
      "c" : {
        "x" : 96,
        "y" : 239
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 96,
        "y" : 239
      }
    },
    "reactionShape" : {
      "a" : {
        "x" : 94,
        "y" : 255
      },
      "b" : {
        "x" : 106,
        "y" : 267
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 100,
        "y" : 261
      }
    },
    "inputs" : [ {
      "id" : 98489
    } ],
    "outputs" : [ {
      "id" : 98491
    } ]
  }, {
    "id" : 98525,
    "reactomeId" : 10037866,
    "displayName" : "Beta defensin 103 activates TLR1:TLR2",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 567,
      "y" : 514
    },
    "minX" : 548,
    "maxX" : 573,
    "minY" : 475,
    "maxY" : 569,
    "reactionType" : "binding",
    "segments" : [ {
      "from" : {
        "x" : 566,
        "y" : 475
      },
      "to" : {
        "x" : 567,
        "y" : 514
      }
    }, {
      "from" : {
        "x" : 567,
        "y" : 514
      },
      "to" : {
        "x" : 548,
        "y" : 569
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 546,
        "y" : 561
      },
      "b" : {
        "x" : 548,
        "y" : 569
      },
      "c" : {
        "x" : 554,
        "y" : 564
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 554,
        "y" : 564
      }
    },
    "reactionShape" : {
      "c" : {
        "x" : 567,
        "y" : 514
      },
      "r" : 5,
      "type" : "CIRCLE",
      "centre" : {
        "x" : 567,
        "y" : 514
      }
    },
    "inputs" : [ {
      "id" : 98526,
      "points" : [ {
        "x" : 547,
        "y" : 456
      } ]
    }, {
      "id" : 98527,
      "points" : [ {
        "x" : 578,
        "y" : 464
      } ]
    } ],
    "outputs" : [ {
      "id" : 98528
    } ]
  }, {
    "id" : 98492,
    "reactomeId" : 10031923,
    "displayName" : "pro-defensin alpha 5 is stored in Paneth cell granules",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 382,
      "y" : 481
    },
    "minX" : 376,
    "maxX" : 388,
    "minY" : 431,
    "maxY" : 514,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 382,
        "y" : 514
      },
      "to" : {
        "x" : 382,
        "y" : 481
      }
    }, {
      "from" : {
        "x" : 382,
        "y" : 481
      },
      "to" : {
        "x" : 382,
        "y" : 431
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 386,
        "y" : 438
      },
      "b" : {
        "x" : 382,
        "y" : 431
      },
      "c" : {
        "x" : 378,
        "y" : 438
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 378,
        "y" : 438
      }
    },
    "reactionShape" : {
      "a" : {
        "x" : 376,
        "y" : 475
      },
      "b" : {
        "x" : 388,
        "y" : 487
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 382,
        "y" : 481
      }
    },
    "inputs" : [ {
      "id" : 98493
    } ],
    "outputs" : [ {
      "id" : 98494
    } ]
  }, {
    "id" : 98495,
    "reactomeId" : 10032243,
    "displayName" : "pro-defensin alpha 5 is secreted",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 382,
      "y" : 313
    },
    "minX" : 376,
    "maxX" : 388,
    "minY" : 115,
    "maxY" : 385,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 382,
        "y" : 385
      },
      "to" : {
        "x" : 382,
        "y" : 313
      }
    }, {
      "from" : {
        "x" : 382,
        "y" : 313
      },
      "to" : {
        "x" : 382,
        "y" : 115
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 386,
        "y" : 122
      },
      "b" : {
        "x" : 382,
        "y" : 115
      },
      "c" : {
        "x" : 378,
        "y" : 122
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 378,
        "y" : 122
      }
    },
    "reactionShape" : {
      "a" : {
        "x" : 376,
        "y" : 307
      },
      "b" : {
        "x" : 388,
        "y" : 319
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 382,
        "y" : 313
      }
    },
    "inputs" : [ {
      "id" : 98494
    } ],
    "outputs" : [ {
      "id" : 98496
    } ]
  } ],
  "compartments" : [ {
    "id" : 98529,
    "reactomeId" : 70101,
    "displayName" : "cytosol",
    "schemaClass" : "Compartment",
    "renderableClass" : "Compartment",
    "position" : {
      "x" : 271,
      "y" : 511
    },
    "minX" : 0,
    "maxX" : 542,
    "minY" : 276,
    "maxY" : 747,
    "prop" : {
      "x" : 0,
      "y" : 276,
      "width" : 542,
      "height" : 471
    },
    "textPosition" : {
      "x" : 468,
      "y" : 686
    },
    "insets" : {
      "x" : 10,
      "y" : 286,
      "width" : 522,
      "height" : 451
    },
    "bgColor" : {
      "r" : 250,
      "g" : 240,
      "b" : 240
    },
    "componentIds" : [ 98530, 98531, 98532, 98495, 98488, 98511, 98509, 98512, 98519, 98492, 98524, 98520, 98526, 98528 ]
  }, {
    "id" : 98531,
    "reactomeId" : 1470028,
    "displayName" : "azurophil granule lumen",
    "schemaClass" : "Compartment",
    "renderableClass" : "Compartment",
    "position" : {
      "x" : 122,
      "y" : 368
    },
    "minX" : 28,
    "maxX" : 216,
    "minY" : 304,
    "maxY" : 432,
    "prop" : {
      "x" : 28,
      "y" : 304,
      "width" : 188,
      "height" : 128
    },
    "textPosition" : {
      "x" : 45,
      "y" : 383
    },
    "insets" : {
      "x" : 38,
      "y" : 314,
      "width" : 168,
      "height" : 108
    },
    "bgColor" : {
      "r" : 250,
      "g" : 240,
      "b" : 240
    },
    "componentIds" : [ 98489 ]
  }, {
    "id" : 98530,
    "reactomeId" : 17963,
    "displayName" : "Golgi lumen",
    "schemaClass" : "Compartment",
    "renderableClass" : "Compartment",
    "position" : {
      "x" : 239,
      "y" : 594
    },
    "minX" : 34,
    "maxX" : 444,
    "minY" : 494,
    "maxY" : 694,
    "prop" : {
      "x" : 34,
      "y" : 494,
      "width" : 410,
      "height" : 200
    },
    "textPosition" : {
      "x" : 338,
      "y" : 644
    },
    "insets" : {
      "x" : 44,
      "y" : 504,
      "width" : 390,
      "height" : 180
    },
    "bgColor" : {
      "r" : 250,
      "g" : 240,
      "b" : 240
    },
    "componentIds" : [ 98481, 98482, 98483, 98484, 98485, 98486, 98493, 98513, 98539, 98487, 98555 ]
  }, {
    "id" : 98532,
    "reactomeId" : 1462052,
    "displayName" : "secretory granule lumen",
    "schemaClass" : "Compartment",
    "renderableClass" : "Compartment",
    "position" : {
      "x" : 389,
      "y" : 419
    },
    "minX" : 292,
    "maxX" : 487,
    "minY" : 362,
    "maxY" : 476,
    "prop" : {
      "x" : 292,
      "y" : 362,
      "width" : 195,
      "height" : 114
    },
    "textPosition" : {
      "x" : 316,
      "y" : 428
    },
    "insets" : {
      "x" : 302,
      "y" : 372,
      "width" : 175,
      "height" : 94
    },
    "bgColor" : {
      "r" : 250,
      "g" : 240,
      "b" : 240
    },
    "componentIds" : [ 98494 ]
  }, {
    "id" : 98535,
    "reactomeId" : 171242,
    "displayName" : "viral envelope",
    "schemaClass" : "Compartment",
    "renderableClass" : "Compartment",
    "position" : {
      "x" : 159,
      "y" : 48
    },
    "minX" : 54,
    "maxX" : 265,
    "minY" : 0,
    "maxY" : 96,
    "prop" : {
      "x" : 54,
      "y" : 0,
      "width" : 211,
      "height" : 96
    },
    "textPosition" : {
      "x" : 109,
      "y" : 31
    },
    "insets" : {
      "x" : 64,
      "y" : 10,
      "width" : 191,
      "height" : 76
    },
    "bgColor" : {
      "r" : 250,
      "g" : 240,
      "b" : 240
    }
  }, {
    "id" : 98534,
    "reactomeId" : 70101,
    "displayName" : "cytosol",
    "schemaClass" : "Compartment",
    "renderableClass" : "Compartment",
    "position" : {
      "x" : 837,
      "y" : 392
    },
    "minX" : 682,
    "maxX" : 993,
    "minY" : 286,
    "maxY" : 499,
    "prop" : {
      "x" : 682,
      "y" : 286,
      "width" : 311,
      "height" : 213
    },
    "textPosition" : {
      "x" : 789,
      "y" : 370
    },
    "insets" : {
      "x" : 692,
      "y" : 296,
      "width" : 291,
      "height" : 193
    },
    "bgColor" : {
      "r" : 250,
      "g" : 240,
      "b" : 240
    },
    "componentIds" : [ 98533, 98505, 98507, 98506, 98504, 98515, 98516 ]
  } ],
  "notes" : [ {
    "id" : 98533,
    "displayName" : "Microbial cell",
    "renderableClass" : "Note",
    "position" : {
      "x" : 818,
      "y" : 368
    },
    "minX" : 767,
    "maxX" : 870,
    "minY" : 358,
    "maxY" : 378,
    "prop" : {
      "x" : 767,
      "y" : 358,
      "width" : 103,
      "height" : 20
    },
    "textPosition" : {
      "x" : 774,
      "y" : 358
    }
  } ],
  "links" : [ {
    "id" : 98539,
    "renderableClass" : "EntitySetAndMemberLink",
    "position" : {
      "x" : 327,
      "y" : 533
    },
    "minX" : 317,
    "maxX" : 338,
    "minY" : 527,
    "maxY" : 539,
    "segments" : [ {
      "from" : {
        "x" : 338,
        "y" : 534
      },
      "to" : {
        "x" : 317,
        "y" : 533
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 321,
        "y" : 527
      },
      "b" : {
        "x" : 333,
        "y" : 539
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 327,
        "y" : 533
      }
    },
    "inputs" : [ {
      "id" : 98493
    } ],
    "outputs" : [ {
      "id" : 98483
    } ]
  }, {
    "id" : 98538,
    "renderableClass" : "EntitySetAndMemberLink",
    "position" : {
      "x" : 588,
      "y" : 117
    },
    "minX" : 582,
    "maxX" : 594,
    "minY" : 107,
    "maxY" : 127,
    "segments" : [ {
      "from" : {
        "x" : 588,
        "y" : 107
      },
      "to" : {
        "x" : 589,
        "y" : 127
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 582,
        "y" : 111
      },
      "b" : {
        "x" : 594,
        "y" : 123
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 588,
        "y" : 117
      }
    },
    "inputs" : [ {
      "id" : 98498
    } ],
    "outputs" : [ {
      "id" : 98501
    } ]
  }, {
    "id" : 98541,
    "renderableClass" : "EntitySetAndMemberLink",
    "position" : {
      "x" : 266,
      "y" : 180
    },
    "minX" : 141,
    "maxX" : 392,
    "minY" : 159,
    "maxY" : 201,
    "segments" : [ {
      "from" : {
        "x" : 392,
        "y" : 201
      },
      "to" : {
        "x" : 141,
        "y" : 159
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 260,
        "y" : 174
      },
      "b" : {
        "x" : 272,
        "y" : 186
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 266,
        "y" : 180
      }
    },
    "inputs" : [ {
      "id" : 98522
    } ],
    "outputs" : [ {
      "id" : 98510
    } ]
  }, {
    "id" : 98540,
    "renderableClass" : "EntitySetAndMemberLink",
    "position" : {
      "x" : 271,
      "y" : 209
    },
    "minX" : 151,
    "maxX" : 392,
    "minY" : 203,
    "maxY" : 215,
    "segments" : [ {
      "from" : {
        "x" : 392,
        "y" : 209
      },
      "to" : {
        "x" : 151,
        "y" : 209
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 265,
        "y" : 203
      },
      "b" : {
        "x" : 277,
        "y" : 215
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 271,
        "y" : 209
      }
    },
    "inputs" : [ {
      "id" : 98522
    } ],
    "outputs" : [ {
      "id" : 98491
    } ]
  }, {
    "id" : 98542,
    "renderableClass" : "EntitySetAndMemberLink",
    "position" : {
      "x" : 519,
      "y" : 178
    },
    "minX" : 474,
    "maxX" : 565,
    "minY" : 161,
    "maxY" : 196,
    "segments" : [ {
      "from" : {
        "x" : 474,
        "y" : 196
      },
      "to" : {
        "x" : 565,
        "y" : 161
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 513,
        "y" : 172
      },
      "b" : {
        "x" : 525,
        "y" : 184
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 519,
        "y" : 178
      }
    },
    "inputs" : [ {
      "id" : 98522
    } ],
    "outputs" : [ {
      "id" : 98501
    } ]
  }, {
    "id" : 98545,
    "renderableClass" : "EntitySetAndEntitySetLink",
    "position" : {
      "x" : 189,
      "y" : 586
    },
    "minX" : 132,
    "maxX" : 246,
    "minY" : 550,
    "maxY" : 622,
    "segments" : [ {
      "from" : {
        "x" : 246,
        "y" : 550
      },
      "to" : {
        "x" : 132,
        "y" : 622
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 183,
        "y" : 580
      },
      "b" : {
        "x" : 195,
        "y" : 592
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 189,
        "y" : 586
      }
    },
    "inputs" : [ {
      "id" : 98483
    } ],
    "outputs" : [ {
      "id" : 98485
    } ]
  }, {
    "id" : 98547,
    "renderableClass" : "EntitySetAndEntitySetLink",
    "position" : {
      "x" : 384,
      "y" : 726
    },
    "minX" : 110,
    "maxX" : 658,
    "minY" : 636,
    "maxY" : 816,
    "segments" : [ {
      "from" : {
        "x" : 658,
        "y" : 636
      },
      "to" : {
        "x" : 110,
        "y" : 816
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 378,
        "y" : 720
      },
      "b" : {
        "x" : 390,
        "y" : 732
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 384,
        "y" : 726
      }
    },
    "inputs" : [ {
      "id" : 98514
    } ],
    "outputs" : [ {
      "id" : 98537
    } ]
  }, {
    "id" : 98546,
    "renderableClass" : "EntitySetAndEntitySetLink",
    "position" : {
      "x" : 313,
      "y" : 576
    },
    "minX" : 276,
    "maxX" : 351,
    "minY" : 550,
    "maxY" : 603,
    "segments" : [ {
      "from" : {
        "x" : 276,
        "y" : 550
      },
      "to" : {
        "x" : 351,
        "y" : 603
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 307,
        "y" : 570
      },
      "b" : {
        "x" : 319,
        "y" : 582
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 313,
        "y" : 576
      }
    },
    "inputs" : [ {
      "id" : 98483
    } ],
    "outputs" : [ {
      "id" : 98513
    } ]
  }, {
    "id" : 98549,
    "renderableClass" : "EntitySetAndEntitySetLink",
    "position" : {
      "x" : 692,
      "y" : 842
    },
    "minX" : 312,
    "maxX" : 698,
    "minY" : 636,
    "maxY" : 848,
    "segments" : [ {
      "from" : {
        "x" : 691,
        "y" : 636
      },
      "to" : {
        "x" : 692,
        "y" : 842
      }
    }, {
      "from" : {
        "x" : 692,
        "y" : 842
      },
      "to" : {
        "x" : 312,
        "y" : 841
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 686,
        "y" : 836
      },
      "b" : {
        "x" : 698,
        "y" : 848
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 692,
        "y" : 842
      }
    },
    "inputs" : [ {
      "id" : 98514
    } ],
    "outputs" : [ {
      "id" : 98518
    } ]
  }, {
    "id" : 98550,
    "renderableClass" : "EntitySetAndEntitySetLink",
    "position" : {
      "x" : 340,
      "y" : 177
    },
    "minX" : 151,
    "maxX" : 530,
    "minY" : 151,
    "maxY" : 203,
    "segments" : [ {
      "from" : {
        "x" : 530,
        "y" : 151
      },
      "to" : {
        "x" : 151,
        "y" : 203
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 334,
        "y" : 171
      },
      "b" : {
        "x" : 346,
        "y" : 183
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 340,
        "y" : 177
      }
    },
    "inputs" : [ {
      "id" : 98501
    } ],
    "outputs" : [ {
      "id" : 98491
    } ]
  }, {
    "id" : 98552,
    "renderableClass" : "EntitySetAndEntitySetLink",
    "position" : {
      "x" : 335,
      "y" : 148
    },
    "minX" : 141,
    "maxX" : 530,
    "minY" : 142,
    "maxY" : 154,
    "segments" : [ {
      "from" : {
        "x" : 530,
        "y" : 144
      },
      "to" : {
        "x" : 141,
        "y" : 152
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 329,
        "y" : 142
      },
      "b" : {
        "x" : 341,
        "y" : 154
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 335,
        "y" : 148
      }
    },
    "inputs" : [ {
      "id" : 98501
    } ],
    "outputs" : [ {
      "id" : 98510
    } ]
  }, {
    "id" : 98554,
    "renderableClass" : "EntitySetAndEntitySetLink",
    "position" : {
      "x" : 98,
      "y" : 180
    },
    "minX" : 92,
    "maxX" : 104,
    "minY" : 174,
    "maxY" : 186,
    "segments" : [ {
      "from" : {
        "x" : 99,
        "y" : 186
      },
      "to" : {
        "x" : 97,
        "y" : 175
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 92,
        "y" : 174
      },
      "b" : {
        "x" : 104,
        "y" : 186
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 98,
        "y" : 180
      }
    },
    "inputs" : [ {
      "id" : 98491
    } ],
    "outputs" : [ {
      "id" : 98510
    } ]
  }, {
    "id" : 98556,
    "renderableClass" : "EntitySetAndEntitySetLink",
    "position" : {
      "x" : 168,
      "y" : 840
    },
    "minX" : 121,
    "maxX" : 215,
    "minY" : 834,
    "maxY" : 846,
    "segments" : [ {
      "from" : {
        "x" : 121,
        "y" : 840
      },
      "to" : {
        "x" : 215,
        "y" : 840
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 162,
        "y" : 834
      },
      "b" : {
        "x" : 174,
        "y" : 846
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 168,
        "y" : 840
      }
    },
    "inputs" : [ {
      "id" : 98537
    } ],
    "outputs" : [ {
      "id" : 98518
    } ]
  } ],
  "shadows" : [ {
    "id" : 98557,
    "reactomeId" : 10100697,
    "displayName" : "Alpha-defensins",
    "schemaClass" : "Pathway",
    "renderableClass" : "Shadow",
    "position" : {
      "x" : 519,
      "y" : 347
    },
    "minX" : 46,
    "maxX" : 992,
    "minY" : 13,
    "maxY" : 681,
    "prop" : {
      "x" : 46,
      "y" : 13,
      "width" : 946,
      "height" : 250
    },
    "points" : [ {
      "x" : 46,
      "y" : 13
    }, {
      "x" : 992,
      "y" : 13
    }, {
      "x" : 992,
      "y" : 681
    }, {
      "x" : 46,
      "y" : 681
    } ],
    "colour" : "#4684ee"
  }, {
    "id" : 98558,
    "reactomeId" : 10100701,
    "displayName" : "Beta defensins",
    "schemaClass" : "Pathway",
    "renderableClass" : "Shadow",
    "position" : {
      "x" : 546,
      "y" : 570
    },
    "minX" : 211,
    "maxX" : 882,
    "minY" : 263,
    "maxY" : 877,
    "prop" : {
      "x" : 211,
      "y" : 681,
      "width" : 671,
      "height" : 196
    },
    "points" : [ {
      "x" : 211,
      "y" : 263
    }, {
      "x" : 882,
      "y" : 263
    }, {
      "x" : 882,
      "y" : 877
    }, {
      "x" : 211,
      "y" : 877
    } ],
    "colour" : "#dc3912"
  } ],
  "minX" : 0,
  "maxX" : 993,
  "minY" : 0,
  "maxY" : 867,
  "disease" : false
}