{
  "dbId" : 10100627,
  "stId" : "R-MMU-1247673",
  "speciesName" : "Mus musculus",
  "nodes" : [ {
    "dbId" : 10029337,
    "stId" : "R-MMU-1244330",
    "displayName" : "SLC4A1 dimer [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 48892,
    "diagramIds" : [ 117534 ],
    "parents" : [ ],
    "children" : [ 10015266 ]
  }, {
    "dbId" : 1237009,
    "stId" : "R-ALL-1237009",
    "displayName" : "CO2 [extracellular region]",
    "schemaClass" : "SimpleEntity",
    "speciesId" : 0,
    "diagramIds" : [ 117536 ],
    "identifier" : "16526",
    "standardIdentifier" : "chebi:16526",
    "referenceType" : "ReferenceMolecule",
    "parents" : [ ],
    "children" : [ ]
  }, {
    "dbId" : 10029407,
    "stId" : "R-MMU-1008268",
    "displayName" : "HBA1 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48892,
    "identifier" : "P01942",
    "standardIdentifier" : "uniprot:P01942",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 10029409 ],
    "children" : [ ]
  }, {
    "dbId" : 111627,
    "stId" : "R-ALL-111627",
    "displayName" : "HCO3- [cytosol]",
    "schemaClass" : "SimpleEntity",
    "speciesId" : 0,
    "diagramIds" : [ 117533 ],
    "identifier" : "17544",
    "standardIdentifier" : "chebi:17544",
    "referenceType" : "ReferenceMolecule",
    "parents" : [ ],
    "children" : [ ]
  }, {
    "dbId" : 351626,
    "stId" : "R-ALL-351626",
    "displayName" : "H+ [extracellular region]",
    "schemaClass" : "SimpleEntity",
    "speciesId" : 0,
    "diagramIds" : [ 117541 ],
    "identifier" : "15378",
    "standardIdentifier" : "chebi:15378",
    "referenceType" : "ReferenceMolecule",
    "parents" : [ ],
    "children" : [ ]
  }, {
    "dbId" : 71185,
    "stId" : "R-ALL-71185",
    "displayName" : "ferroheme [cytosol]",
    "schemaClass" : "SimpleEntity",
    "speciesId" : 0,
    "identifier" : "60344",
    "standardIdentifier" : "chebi:60344",
    "referenceType" : "ReferenceMolecule",
    "parents" : [ 10029423, 10029429, 10029415, 10029409 ],
    "children" : [ ]
  }, {
    "dbId" : 109265,
    "stId" : "R-ALL-109265",
    "displayName" : "Zn2+ [plasma membrane]",
    "schemaClass" : "SimpleEntity",
    "speciesId" : 0,
    "identifier" : "29105",
    "standardIdentifier" : "chebi:29105",
    "referenceType" : "ReferenceMolecule",
    "parents" : [ 10029359 ],
    "children" : [ ]
  }, {
    "dbId" : 10016523,
    "stId" : "R-MMU-431700",
    "displayName" : "Aqp1 [plasma membrane]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48892,
    "identifier" : "Q02013",
    "standardIdentifier" : "uniprot:Q02013",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Aqp1" ],
    "parents" : [ 10016525 ],
    "children" : [ ]
  }, {
    "dbId" : 352022,
    "stId" : "R-ALL-352022",
    "displayName" : "Cl- [cytosol]",
    "schemaClass" : "SimpleEntity",
    "speciesId" : 0,
    "diagramIds" : [ 117530 ],
    "identifier" : "17996",
    "standardIdentifier" : "chebi:17996",
    "referenceType" : "ReferenceMolecule",
    "parents" : [ ],
    "children" : [ ]
  }, {
    "dbId" : 10033098,
    "stId" : "R-MMU-1237012",
    "displayName" : "CA2 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48892,
    "identifier" : "P00920",
    "standardIdentifier" : "uniprot:P00920",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 10033100 ],
    "children" : [ ]
  }, {
    "dbId" : 10033165,
    "stId" : "R-MMU-1475437",
    "displayName" : "CA1:Zn2+,CA2:Zn2+ [cytosol]",
    "schemaClass" : "DefinedSet",
    "speciesId" : 48892,
    "diagramIds" : [ 117546 ],
    "parents" : [ ],
    "children" : [ 10033094, 10033100 ]
  }, {
    "dbId" : 10016525,
    "stId" : "R-MMU-432246",
    "displayName" : "AQP1 tetramer [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 48892,
    "diagramIds" : [ 117537 ],
    "parents" : [ ],
    "children" : [ 10016523 ]
  }, {
    "dbId" : 10033100,
    "stId" : "R-MMU-1237310",
    "displayName" : "CA2:Zn2+ [cytosol]",
    "schemaClass" : "Complex",
    "speciesId" : 48892,
    "parents" : [ 10033165 ],
    "children" : [ 10033098, 29426 ]
  }, {
    "dbId" : 425425,
    "stId" : "R-ALL-425425",
    "displayName" : "HCO3- [extracellular region]",
    "schemaClass" : "SimpleEntity",
    "speciesId" : 0,
    "diagramIds" : [ 117531 ],
    "identifier" : "17544",
    "standardIdentifier" : "chebi:17544",
    "referenceType" : "ReferenceMolecule",
    "parents" : [ ],
    "children" : [ ]
  }, {
    "dbId" : 70106,
    "stId" : "R-ALL-70106",
    "displayName" : "H+ [cytosol]",
    "schemaClass" : "SimpleEntity",
    "speciesId" : 0,
    "diagramIds" : [ 117527 ],
    "identifier" : "15378",
    "standardIdentifier" : "chebi:15378",
    "referenceType" : "ReferenceMolecule",
    "parents" : [ ],
    "children" : [ ]
  }, {
    "dbId" : 10033092,
    "stId" : "R-MMU-1237027",
    "displayName" : "CA1 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48892,
    "identifier" : "P13634",
    "standardIdentifier" : "uniprot:P13634",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 10033094 ],
    "children" : [ ]
  }, {
    "dbId" : 109276,
    "stId" : "R-ALL-109276",
    "displayName" : "H2O [extracellular region]",
    "schemaClass" : "SimpleEntity",
    "speciesId" : 0,
    "diagramIds" : [ 117542 ],
    "identifier" : "15377",
    "standardIdentifier" : "chebi:15377",
    "referenceType" : "ReferenceMolecule",
    "parents" : [ ],
    "children" : [ ]
  }, {
    "dbId" : 10033094,
    "stId" : "R-MMU-1237322",
    "displayName" : "CA1:Zn2+ [cytosol]",
    "schemaClass" : "Complex",
    "speciesId" : 48892,
    "parents" : [ 10033165 ],
    "children" : [ 10033092, 29426 ]
  }, {
    "dbId" : 10029427,
    "stId" : "R-MMU-1237013",
    "displayName" : "Hbb-bs [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48892,
    "identifier" : "A8DUK4",
    "standardIdentifier" : "uniprot:A8DUK4",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Hbb-bs" ],
    "parents" : [ 10029429 ],
    "children" : [ ]
  }, {
    "dbId" : 10029429,
    "stId" : "R-MMU-1237318",
    "displayName" : "Protonated Carbamino Hemoglobin beta: ferroheme b [cytosol]",
    "schemaClass" : "Complex",
    "speciesId" : 48892,
    "parents" : [ 10029431 ],
    "children" : [ 10029427, 71185 ]
  }, {
    "dbId" : 29356,
    "stId" : "R-ALL-29356",
    "displayName" : "H2O [cytosol]",
    "schemaClass" : "SimpleEntity",
    "speciesId" : 0,
    "diagramIds" : [ 117545 ],
    "identifier" : "15377",
    "standardIdentifier" : "chebi:15377",
    "referenceType" : "ReferenceMolecule",
    "parents" : [ ],
    "children" : [ ]
  }, {
    "dbId" : 188972,
    "stId" : "R-ALL-188972",
    "displayName" : "Cl- [extracellular region]",
    "schemaClass" : "SimpleEntity",
    "speciesId" : 0,
    "diagramIds" : [ 117532 ],
    "identifier" : "17996",
    "standardIdentifier" : "chebi:17996",
    "referenceType" : "ReferenceMolecule",
    "parents" : [ ],
    "children" : [ ]
  }, {
    "dbId" : 10029431,
    "stId" : "R-MMU-1237312",
    "displayName" : "Protonated Carbamino DeoxyHbA [cytosol]",
    "schemaClass" : "Complex",
    "speciesId" : 48892,
    "diagramIds" : [ 117524 ],
    "parents" : [ ],
    "children" : [ 10029429, 10029423 ]
  }, {
    "dbId" : 10029417,
    "stId" : "R-MMU-1237320",
    "displayName" : "OxyHbA [cytosol]",
    "schemaClass" : "Complex",
    "speciesId" : 48892,
    "diagramIds" : [ 117526 ],
    "parents" : [ ],
    "children" : [ 10029415, 10029409 ]
  }, {
    "dbId" : 29426,
    "stId" : "R-ALL-29426",
    "displayName" : "Zn2+ [cytosol]",
    "schemaClass" : "SimpleEntity",
    "speciesId" : 0,
    "identifier" : "29105",
    "standardIdentifier" : "chebi:29105",
    "referenceType" : "ReferenceMolecule",
    "parents" : [ 10033100, 10033094 ],
    "children" : [ ]
  }, {
    "dbId" : 10029421,
    "stId" : "R-MMU-1237026",
    "displayName" : "CO-H+-HBA1 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48892,
    "identifier" : "P01942",
    "standardIdentifier" : "uniprot:P01942",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 10029423 ],
    "children" : [ ]
  }, {
    "dbId" : 10029357,
    "stId" : "R-MMU-1237024",
    "displayName" : "N-seryl-glycosylphosphatidylinositolethanolamine-CA4 [plasma membrane]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48892,
    "identifier" : "Q64444",
    "standardIdentifier" : "uniprot:Q64444",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 10029359 ],
    "children" : [ ]
  }, {
    "dbId" : 10029423,
    "stId" : "R-MMU-1237317",
    "displayName" : "Protonated Carbamino Hemoglobin alpha:ferroheme b [cytosol]",
    "schemaClass" : "Complex",
    "speciesId" : 48892,
    "parents" : [ 10029431 ],
    "children" : [ 10029421, 71185 ]
  }, {
    "dbId" : 10029359,
    "stId" : "R-MMU-1237308",
    "displayName" : "CA4:Zn2+ [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 48892,
    "diagramIds" : [ 117543 ],
    "parents" : [ ],
    "children" : [ 10029357, 109265 ]
  }, {
    "dbId" : 29368,
    "stId" : "R-ALL-29368",
    "displayName" : "O2 [cytosol]",
    "schemaClass" : "SimpleEntity",
    "speciesId" : 0,
    "diagramIds" : [ 117525 ],
    "identifier" : "15379",
    "standardIdentifier" : "chebi:15379",
    "referenceType" : "ReferenceMolecule",
    "parents" : [ 10029415, 10029409 ],
    "children" : [ ]
  }, {
    "dbId" : 10029409,
    "stId" : "R-MMU-1237036",
    "displayName" : "Hemoglobin alpha:ferroheme b:oxygen [cytosol]",
    "schemaClass" : "Complex",
    "speciesId" : 48892,
    "parents" : [ 10029417 ],
    "children" : [ 29368, 10029407, 71185 ]
  }, {
    "dbId" : 10017376,
    "stId" : "R-MMU-444408",
    "displayName" : "Rhag [plasma membrane]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48892,
    "diagramIds" : [ 117539 ],
    "identifier" : "Q9QUT0",
    "standardIdentifier" : "uniprot:Q9QUT0",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Rhag" ],
    "parents" : [ ],
    "children" : [ ]
  }, {
    "dbId" : 113528,
    "stId" : "R-ALL-113528",
    "displayName" : "CO2 [cytosol]",
    "schemaClass" : "SimpleEntity",
    "speciesId" : 0,
    "diagramIds" : [ 117528 ],
    "identifier" : "16526",
    "standardIdentifier" : "chebi:16526",
    "referenceType" : "ReferenceMolecule",
    "parents" : [ ],
    "children" : [ ]
  }, {
    "dbId" : 10015266,
    "stId" : "R-MMU-420408",
    "displayName" : "Slc4a1 [plasma membrane]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48892,
    "identifier" : "P04919",
    "standardIdentifier" : "uniprot:P04919",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Slc4a1" ],
    "parents" : [ 10029337 ],
    "children" : [ ]
  }, {
    "dbId" : 10029413,
    "stId" : "R-MMU-1008196",
    "displayName" : "Hbb-bs [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48892,
    "identifier" : "A8DUK4",
    "standardIdentifier" : "uniprot:A8DUK4",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Hbb-bs" ],
    "parents" : [ 10029415 ],
    "children" : [ ]
  }, {
    "dbId" : 10029415,
    "stId" : "R-MMU-1237037",
    "displayName" : "Hemoglobin beta:ferroheme b:oxygen [cytosol]",
    "schemaClass" : "Complex",
    "speciesId" : 48892,
    "parents" : [ 10029417 ],
    "children" : [ 10029413, 29368, 71185 ]
  } ],
  "edges" : [ {
    "dbId" : 10029449,
    "stId" : "R-MMU-1247649",
    "displayName" : "AQP1 tetramer transports CO2 from cytosol to extracellular region",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "preceding" : [ 10033170, 10029453 ],
    "inputs" : [ 113528 ],
    "outputs" : [ 1237009 ],
    "catalysts" : [ 10016525 ],
    "efs" : [ ],
    "diagramIds" : [ 117535 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10029451,
    "stId" : "R-MMU-1247665",
    "displayName" : "SLC4A1 exchanges cytosolic Cl- for extracellular HCO3-",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "following" : [ 10033170 ],
    "inputs" : [ 425425, 352022 ],
    "outputs" : [ 188972, 111627 ],
    "catalysts" : [ 10029337 ],
    "efs" : [ ],
    "diagramIds" : [ 117529 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10029453,
    "stId" : "R-MMU-1247668",
    "displayName" : "Hemoglobin A binds O2, releasing H+ and CO2",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "following" : [ 10029449, 10029447, 10033170 ],
    "inputs" : [ 10029431, 29368 ],
    "outputs" : [ 70106, 113528, 10029417 ],
    "efs" : [ ],
    "diagramIds" : [ 117523 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10033170,
    "stId" : "R-MMU-1475436",
    "displayName" : "CA1:Zn2+,CA2:Zn2+ dehydrate HCO3- to CO2",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "preceding" : [ 10029453, 10029451 ],
    "following" : [ 10029449, 10029447 ],
    "inputs" : [ 70106, 111627 ],
    "outputs" : [ 29356, 113528 ],
    "catalysts" : [ 10033165 ],
    "efs" : [ ],
    "diagramIds" : [ 117544 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10029364,
    "stId" : "R-MMU-1237059",
    "displayName" : "CA4:Zn2+ dehydrates HCO3- to CO2",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "inputs" : [ 351626, 425425 ],
    "outputs" : [ 109276, 1237009 ],
    "catalysts" : [ 10029359 ],
    "efs" : [ ],
    "diagramIds" : [ 117540 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10029447,
    "stId" : "R-MMU-1247645",
    "displayName" : "RHAG transports CO2 from cytosol to extracellular region",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "preceding" : [ 10033170, 10029453 ],
    "inputs" : [ 113528 ],
    "outputs" : [ 1237009 ],
    "catalysts" : [ 10017376 ],
    "efs" : [ ],
    "diagramIds" : [ 117538 ],
    "entityFunctionalStatus" : [ ]
  } ]
}