{ "dbId" : 10100561, "stableId" : "R-MMU-983231", "displayName" : "Factors involved in megakaryocyte development and platelet production", "nodes" : [ { "id" : 74119, "reactomeId" : 10027078, "displayName" : "RAD51C", "schemaClass" : "EntityWithAccessionedSequence", "renderableClass" : "Protein", "position" : { "x" : 397, "y" : 70 }, "minX" : 367, "maxX" : 435, "minY" : 54, "maxY" : 94, "prop" : { "x" : 367, "y" : 60, "width" : 60, "height" : 20 }, "textPosition" : { "x" : 368, "y" : 60 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 427, "y" : 60 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 427, "y" : 60 } } }, "connectors" : [ { "edgeId" : 74117, "type" : "INPUT", "segments" : [ { "from" : { "x" : 412, "y" : 83 }, "to" : { "x" : 435, "y" : 94 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 74118, "reactomeId" : 10027074, "displayName" : "RAD51B", "schemaClass" : "EntityWithAccessionedSequence", "renderableClass" : "Protein", "position" : { "x" : 399, "y" : 121 }, "minX" : 370, "maxX" : 435, "minY" : 94, "maxY" : 132, "prop" : { "x" : 370, "y" : 111, "width" : 58, "height" : 21 }, "textPosition" : { "x" : 370, "y" : 111 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 428, "y" : 111 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 428, "y" : 111 } } }, "connectors" : [ { "edgeId" : 74117, "type" : "INPUT", "segments" : [ { "from" : { "x" : 413, "y" : 108 }, "to" : { "x" : 435, "y" : 94 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 74120, "reactomeId" : 10027080, "displayName" : "RAD51B:RAD51C", "schemaClass" : "Complex", "renderableClass" : "Complex", "position" : { "x" : 556, "y" : 92 }, "minX" : 514, "maxX" : 660, "minY" : 69, "maxY" : 148, "prop" : { "x" : 514, "y" : 75, "width" : 85, "height" : 34 }, "textPosition" : { "x" : 526, "y" : 74 }, "bgColor" : { "r" : 204, "g" : 255, "b" : 255 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 599, "y" : 75 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 599, "y" : 75 } } }, "connectors" : [ { "edgeId" : 74117, "type" : "OUTPUT", "segments" : [ ], "stoichiometry" : { "value" : 1 } }, { "edgeId" : 74121, "type" : "INPUT", "segments" : [ { "from" : { "x" : 587, "y" : 112 }, "to" : { "x" : 660, "y" : 148 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 74123, "reactomeId" : 10027082, "displayName" : "RAD51B:RAD51C:Single-stranded DNA", "schemaClass" : "Complex", "renderableClass" : "Complex", "position" : { "x" : 807, "y" : 146 }, "minX" : 745, "maxX" : 875, "minY" : 113, "maxY" : 173, "prop" : { "x" : 745, "y" : 119, "width" : 124, "height" : 54 }, "textPosition" : { "x" : 750, "y" : 124 }, "bgColor" : { "r" : 204, "g" : 255, "b" : 255 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 869, "y" : 119 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 869, "y" : 119 } } }, "connectors" : [ { "edgeId" : 74121, "type" : "OUTPUT", "segments" : [ ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 74122, "reactomeId" : 29868, "displayName" : "Single-stranded DNA", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 565, "y" : 171 }, "minX" : 500, "maxX" : 660, "minY" : 148, "maxY" : 185, "prop" : { "x" : 500, "y" : 157, "width" : 130, "height" : 28 }, "textPosition" : { "x" : 509, "y" : 154 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 625, "y" : 162 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 625, "y" : 162 } } }, "connectors" : [ { "edgeId" : 74121, "type" : "INPUT", "segments" : [ { "from" : { "x" : 622, "y" : 154 }, "to" : { "x" : 660, "y" : 148 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 74125, "reactomeId" : 9992289, "displayName" : "PKA tetramer", "schemaClass" : "Complex", "renderableClass" : "Complex", "position" : { "x" : 1890, "y" : 507 }, "minX" : 1845, "maxX" : 1942, "minY" : 490, "maxY" : 541, "prop" : { "x" : 1845, "y" : 496, "width" : 91, "height" : 22 }, "textPosition" : { "x" : 1845, "y" : 497 }, "bgColor" : { "r" : 204, "g" : 255, "b" : 255 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1936, "y" : 496 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1936, "y" : 496 } } }, "connectors" : [ { "edgeId" : 74124, "type" : "INPUT", "segments" : [ { "from" : { "x" : 1897, "y" : 521 }, "to" : { "x" : 1914, "y" : 541 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 74127, "reactomeId" : 10027952, "displayName" : "Dual-specific AKAPs:PKA tetramer", "schemaClass" : "Complex", "renderableClass" : "Complex", "position" : { "x" : 2058, "y" : 542 }, "minX" : 1994, "maxX" : 2129, "minY" : 511, "maxY" : 567, "prop" : { "x" : 1994, "y" : 517, "width" : 129, "height" : 50 }, "textPosition" : { "x" : 2013, "y" : 518 }, "bgColor" : { "r" : 204, "g" : 255, "b" : 255 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 2123, "y" : 517 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 2123, "y" : 517 } } }, "connectors" : [ { "edgeId" : 74124, "type" : "OUTPUT", "segments" : [ ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 74126, "reactomeId" : 10027950, "displayName" : "Dual-specific AKAPs", "schemaClass" : "DefinedSet", "renderableClass" : "EntitySet", "position" : { "x" : 1898, "y" : 587 }, "minX" : 1858, "maxX" : 1938, "minY" : 541, "maxY" : 613, "prop" : { "x" : 1858, "y" : 562, "width" : 80, "height" : 51 }, "textPosition" : { "x" : 1868, "y" : 563 }, "connectors" : [ { "edgeId" : 74124, "type" : "INPUT", "segments" : [ { "from" : { "x" : 1906, "y" : 556 }, "to" : { "x" : 1914, "y" : 541 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 74129, "reactomeId" : 10027937, "displayName" : "Mitofusins", "schemaClass" : "CandidateSet", "renderableClass" : "EntitySet", "position" : { "x" : 1544, "y" : 70 }, "minX" : 1508, "maxX" : 1616, "minY" : 59, "maxY" : 81, "prop" : { "x" : 1508, "y" : 59, "width" : 72, "height" : 22 }, "textPosition" : { "x" : 1508, "y" : 59 }, "connectors" : [ { "edgeId" : 74128, "type" : "INPUT", "segments" : [ ], "stoichiometry" : { "value" : 2, "shape" : { "a" : { "x" : 1604, "y" : 63 }, "b" : { "x" : 1616, "y" : 75 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 1610, "y" : 69 } } } } ] }, { "id" : 74130, "reactomeId" : 10027939, "displayName" : "Mitofusin complex", "schemaClass" : "Complex", "renderableClass" : "Complex", "position" : { "x" : 1725, "y" : 69 }, "minX" : 1665, "maxX" : 1791, "minY" : 52, "maxY" : 80, "prop" : { "x" : 1665, "y" : 58, "width" : 120, "height" : 22 }, "textPosition" : { "x" : 1665, "y" : 59 }, "bgColor" : { "r" : 204, "g" : 255, "b" : 255 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1785, "y" : 58 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1785, "y" : 58 } } }, "connectors" : [ { "edgeId" : 74128, "type" : "OUTPUT", "segments" : [ ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 74133, "reactomeId" : 10027974, "displayName" : "Histone H3 methylated at lysine-9", "schemaClass" : "DefinedSet", "renderableClass" : "EntitySet", "position" : { "x" : 146, "y" : 588 }, "minX" : 101, "maxX" : 223, "minY" : 554, "maxY" : 613, "prop" : { "x" : 101, "y" : 564, "width" : 91, "height" : 49 }, "textPosition" : { "x" : 105, "y" : 564 }, "connectors" : [ { "edgeId" : 74131, "type" : "INPUT", "segments" : [ { "from" : { "x" : 198, "y" : 567 }, "to" : { "x" : 223, "y" : 554 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 74132, "reactomeId" : 4616022, "displayName" : "Cbx5", "schemaClass" : "EntityWithAccessionedSequence", "renderableClass" : "Protein", "position" : { "x" : 155, "y" : 514 }, "minX" : 125, "maxX" : 223, "minY" : 496, "maxY" : 554, "prop" : { "x" : 125, "y" : 502, "width" : 60, "height" : 25 }, "textPosition" : { "x" : 136, "y" : 504 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 185, "y" : 502 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 185, "y" : 502 } } }, "connectors" : [ { "edgeId" : 74131, "type" : "INPUT", "segments" : [ { "from" : { "x" : 176, "y" : 530 }, "to" : { "x" : 223, "y" : 554 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 74134, "reactomeId" : 10027976, "displayName" : "HP1alpha:Histone H3 methylated at K9", "schemaClass" : "Complex", "renderableClass" : "Complex", "position" : { "x" : 377, "y" : 551 }, "minX" : 314, "maxX" : 447, "minY" : 520, "maxY" : 577, "prop" : { "x" : 314, "y" : 526, "width" : 127, "height" : 51 }, "textPosition" : { "x" : 315, "y" : 528 }, "bgColor" : { "r" : 204, "g" : 255, "b" : 255 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 441, "y" : 526 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 441, "y" : 526 } } }, "connectors" : [ { "edgeId" : 74131, "type" : "OUTPUT", "segments" : [ ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 74137, "reactomeId" : 994149, "displayName" : "I(3,4,5,6)P4", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 1598, "y" : 297 }, "minX" : 1554, "maxX" : 1645, "minY" : 284, "maxY" : 333, "prop" : { "x" : 1554, "y" : 285, "width" : 89, "height" : 24 }, "textPosition" : { "x" : 1558, "y" : 286 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1638, "y" : 290 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1638, "y" : 290 } } }, "connectors" : [ { "edgeId" : 74135, "type" : "INPUT", "segments" : [ { "from" : { "x" : 1613, "y" : 312 }, "to" : { "x" : 1645, "y" : 333 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 74136, "reactomeId" : 113592, "displayName" : "ATP", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 1593, "y" : 363 }, "minX" : 1575, "maxX" : 1645, "minY" : 333, "maxY" : 443, "prop" : { "x" : 1575, "y" : 349, "width" : 37, "height" : 29 }, "textPosition" : { "x" : 1578, "y" : 353 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1607, "y" : 354 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1607, "y" : 354 } } }, "connectors" : [ { "edgeId" : 74135, "type" : "INPUT", "segments" : [ { "from" : { "x" : 1615, "y" : 352 }, "to" : { "x" : 1645, "y" : 333 } } ], "stoichiometry" : { "value" : 1 } }, { "edgeId" : 74141, "type" : "INPUT", "segments" : [ { "from" : { "x" : 1601, "y" : 381 }, "to" : { "x" : 1638, "y" : 443 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 74139, "reactomeId" : 994141, "displayName" : "I(1,3,4,5,6)P5", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 1742, "y" : 295 }, "minX" : 1686, "maxX" : 1799, "minY" : 280, "maxY" : 333, "prop" : { "x" : 1686, "y" : 281, "width" : 112, "height" : 28 }, "textPosition" : { "x" : 1695, "y" : 284 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1793, "y" : 286 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1793, "y" : 286 } } }, "connectors" : [ { "edgeId" : 74135, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 1725, "y" : 312 }, "to" : { "x" : 1697, "y" : 333 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 1722, "y" : 319 }, "b" : { "x" : 1725, "y" : 312 }, "c" : { "x" : 1717, "y" : 313 }, "type" : "ARROW", "centre" : { "x" : 1717, "y" : 313 } } } ] }, { "id" : 74138, "reactomeId" : 29370, "displayName" : "ADP", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 1747, "y" : 372 }, "minX" : 1680, "maxX" : 1768, "minY" : 333, "maxY" : 442, "prop" : { "x" : 1728, "y" : 358, "width" : 39, "height" : 29 }, "textPosition" : { "x" : 1731, "y" : 362 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1762, "y" : 363 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1762, "y" : 363 } } }, "connectors" : [ { "edgeId" : 74135, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 1728, "y" : 355 }, "to" : { "x" : 1697, "y" : 333 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 1720, "y" : 354 }, "b" : { "x" : 1728, "y" : 355 }, "c" : { "x" : 1725, "y" : 348 }, "type" : "ARROW", "centre" : { "x" : 1725, "y" : 348 } } }, { "edgeId" : 74141, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 1733, "y" : 390 }, "to" : { "x" : 1680, "y" : 442 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 1731, "y" : 398 }, "b" : { "x" : 1733, "y" : 390 }, "c" : { "x" : 1725, "y" : 392 }, "type" : "ARROW", "centre" : { "x" : 1725, "y" : 392 } } } ] }, { "id" : 74140, "reactomeId" : 10027982, "displayName" : "ITPK1", "schemaClass" : "EntityWithAccessionedSequence", "renderableClass" : "Protein", "position" : { "x" : 1670, "y" : 385 }, "minX" : 1646, "maxX" : 1700, "minY" : 342, "maxY" : 487, "prop" : { "x" : 1646, "y" : 372, "width" : 48, "height" : 27 }, "textPosition" : { "x" : 1649, "y" : 375 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1694, "y" : 372 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1694, "y" : 372 } } }, "connectors" : [ { "edgeId" : 74182, "type" : "CATALYST", "segments" : [ { "from" : { "x" : 1670, "y" : 402 }, "to" : { "x" : 1677, "y" : 479 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "c" : { "x" : 1677, "y" : 483 }, "r" : 4, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1677, "y" : 483 } } }, { "edgeId" : 74135, "type" : "CATALYST", "segments" : [ { "from" : { "x" : 1670, "y" : 369 }, "to" : { "x" : 1670, "y" : 350 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "c" : { "x" : 1670, "y" : 346 }, "r" : 4, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1670, "y" : 346 } } }, { "edgeId" : 74141, "type" : "CATALYST", "segments" : [ { "from" : { "x" : 1668, "y" : 402 }, "to" : { "x" : 1664, "y" : 426 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "c" : { "x" : 1664, "y" : 430 }, "r" : 4, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1664, "y" : 430 } } } ] }, { "id" : 74143, "reactomeId" : 994170, "displayName" : "I(1,3,4,5)P4", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 1758, "y" : 442 }, "minX" : 1680, "maxX" : 1803, "minY" : 426, "maxY" : 457, "prop" : { "x" : 1715, "y" : 427, "width" : 87, "height" : 30 }, "textPosition" : { "x" : 1718, "y" : 431 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1797, "y" : 432 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1797, "y" : 432 } } }, "connectors" : [ { "edgeId" : 74141, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 1712, "y" : 442 }, "to" : { "x" : 1680, "y" : 442 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 1705, "y" : 446 }, "b" : { "x" : 1712, "y" : 442 }, "c" : { "x" : 1705, "y" : 438 }, "type" : "ARROW", "centre" : { "x" : 1705, "y" : 438 } } } ] }, { "id" : 74142, "reactomeId" : 994123, "displayName" : "I(1,3,4)P3", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 1589, "y" : 466 }, "minX" : 1554, "maxX" : 1642, "minY" : 443, "maxY" : 494, "prop" : { "x" : 1554, "y" : 453, "width" : 71, "height" : 26 }, "textPosition" : { "x" : 1555, "y" : 455 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1620, "y" : 458 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1620, "y" : 458 } } }, "connectors" : [ { "edgeId" : 74182, "type" : "INPUT", "segments" : [ { "from" : { "x" : 1613, "y" : 482 }, "to" : { "x" : 1642, "y" : 494 } } ], "stoichiometry" : { "value" : 1 } }, { "edgeId" : 74141, "type" : "INPUT", "segments" : [ { "from" : { "x" : 1616, "y" : 450 }, "to" : { "x" : 1638, "y" : 443 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 74145, "reactomeId" : 10027998, "displayName" : "REST:REST DNA binding sites", "schemaClass" : "Complex", "renderableClass" : "Complex", "position" : { "x" : 120, "y" : 858 }, "minX" : 73, "maxX" : 177, "minY" : 827, "maxY" : 896, "prop" : { "x" : 73, "y" : 833, "width" : 94, "height" : 51 }, "textPosition" : { "x" : 76, "y" : 835 }, "bgColor" : { "r" : 204, "g" : 255, "b" : 255 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 167, "y" : 833 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 167, "y" : 833 } } }, "connectors" : [ { "edgeId" : 74144, "type" : "INPUT", "segments" : [ { "from" : { "x" : 158, "y" : 887 }, "to" : { "x" : 177, "y" : 896 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 74147, "reactomeId" : 10028014, "displayName" : "BHC complex:REST:REST DNA binding sites", "schemaClass" : "Complex", "renderableClass" : "Complex", "position" : { "x" : 295, "y" : 895 }, "minX" : 237, "maxX" : 359, "minY" : 865, "maxY" : 920, "prop" : { "x" : 237, "y" : 871, "width" : 116, "height" : 49 }, "textPosition" : { "x" : 241, "y" : 871 }, "bgColor" : { "r" : 204, "g" : 255, "b" : 255 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 353, "y" : 871 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 353, "y" : 871 } } }, "connectors" : [ { "edgeId" : 74144, "type" : "OUTPUT", "segments" : [ ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 74146, "reactomeId" : 10028012, "displayName" : "BHC complex", "schemaClass" : "Complex", "renderableClass" : "Complex", "position" : { "x" : 116, "y" : 929 }, "minX" : 72, "maxX" : 177, "minY" : 896, "maxY" : 940, "prop" : { "x" : 72, "y" : 918, "width" : 89, "height" : 22 }, "textPosition" : { "x" : 72, "y" : 919 }, "bgColor" : { "r" : 204, "g" : 255, "b" : 255 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 161, "y" : 918 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 161, "y" : 918 } } }, "connectors" : [ { "edgeId" : 74144, "type" : "INPUT", "segments" : [ { "from" : { "x" : 136, "y" : 915 }, "to" : { "x" : 177, "y" : 896 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 74149, "reactomeId" : 10028038, "displayName" : "GATA proteins", "schemaClass" : "DefinedSet", "renderableClass" : "EntitySet", "position" : { "x" : 446, "y" : 920 }, "minX" : 392, "maxX" : 501, "minY" : 892, "maxY" : 933, "prop" : { "x" : 392, "y" : 907, "width" : 109, "height" : 26 }, "textPosition" : { "x" : 398, "y" : 909 }, "connectors" : [ { "edgeId" : 74148, "type" : "INPUT", "segments" : [ { "from" : { "x" : 465, "y" : 901 }, "to" : { "x" : 489, "y" : 892 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 74151, "reactomeId" : 10028040, "displayName" : "ZFPM proteins:GATA proteins", "schemaClass" : "Complex", "renderableClass" : "Complex", "position" : { "x" : 617, "y" : 892 }, "minX" : 554, "maxX" : 686, "minY" : 869, "maxY" : 910, "prop" : { "x" : 554, "y" : 875, "width" : 126, "height" : 35 }, "textPosition" : { "x" : 566, "y" : 875 }, "bgColor" : { "r" : 204, "g" : 255, "b" : 255 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 680, "y" : 875 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 680, "y" : 875 } } }, "connectors" : [ { "edgeId" : 74148, "type" : "OUTPUT", "segments" : [ ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 74150, "reactomeId" : 10028023, "displayName" : "ZFPM1, ZFPM2", "schemaClass" : "DefinedSet", "renderableClass" : "EntitySet", "position" : { "x" : 445, "y" : 866 }, "minX" : 394, "maxX" : 497, "minY" : 856, "maxY" : 892, "prop" : { "x" : 394, "y" : 856, "width" : 103, "height" : 21 }, "textPosition" : { "x" : 395, "y" : 856 }, "connectors" : [ { "edgeId" : 74148, "type" : "INPUT", "segments" : [ { "from" : { "x" : 462, "y" : 883 }, "to" : { "x" : 489, "y" : 892 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 74153, "reactomeId" : 10028056, "displayName" : "Histone H3 mono or di-methylated at K9", "schemaClass" : "DefinedSet", "renderableClass" : "EntitySet", "position" : { "x" : 146, "y" : 663 }, "minX" : 80, "maxX" : 213, "minY" : 643, "maxY" : 684, "prop" : { "x" : 80, "y" : 643, "width" : 133, "height" : 41 }, "textPosition" : { "x" : 78, "y" : 646 }, "connectors" : [ { "edgeId" : 74152, "type" : "INPUT", "segments" : [ ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 74155, "reactomeId" : 10028062, "displayName" : "JMJD1C", "schemaClass" : "EntityWithAccessionedSequence", "renderableClass" : "Protein", "position" : { "x" : 239, "y" : 720 }, "minX" : 201, "maxX" : 283, "minY" : 671, "maxY" : 732, "prop" : { "x" : 201, "y" : 709, "width" : 76, "height" : 23 }, "textPosition" : { "x" : 214, "y" : 710 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 277, "y" : 709 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 277, "y" : 709 } } }, "connectors" : [ { "edgeId" : 74152, "type" : "CATALYST", "segments" : [ { "from" : { "x" : 239, "y" : 706 }, "to" : { "x" : 239, "y" : 679 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "c" : { "x" : 239, "y" : 675 }, "r" : 4, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 239, "y" : 675 } } } ] }, { "id" : 74154, "reactomeId" : 10028058, "displayName" : "Histone H3 mono- or unmethylated at K9", "schemaClass" : "DefinedSet", "renderableClass" : "EntitySet", "position" : { "x" : 337, "y" : 663 }, "minX" : 269, "maxX" : 406, "minY" : 642, "maxY" : 684, "prop" : { "x" : 269, "y" : 642, "width" : 137, "height" : 42 }, "textPosition" : { "x" : 267, "y" : 645 }, "connectors" : [ { "edgeId" : 74152, "type" : "OUTPUT", "segments" : [ ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 74157, "reactomeId" : 10028050, "displayName" : "phospho-p-Y813-JAK2", "schemaClass" : "EntityWithAccessionedSequence", "renderableClass" : "Protein", "position" : { "x" : 1872, "y" : 192 }, "minX" : 1838, "maxX" : 1931, "minY" : 169, "maxY" : 209, "prop" : { "x" : 1838, "y" : 175, "width" : 69, "height" : 34 }, "textPosition" : { "x" : 1839, "y" : 168 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1907, "y" : 175 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1907, "y" : 175 } } }, "connectors" : [ { "edgeId" : 74156, "type" : "INPUT", "segments" : [ { "from" : { "x" : 1910, "y" : 199 }, "to" : { "x" : 1931, "y" : 204 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 74159, "reactomeId" : 10028052, "displayName" : "SH2B family:p-Y813-JAK2", "schemaClass" : "Complex", "renderableClass" : "Complex", "position" : { "x" : 2039, "y" : 204 }, "minX" : 1976, "maxX" : 2108, "minY" : 181, "maxY" : 222, "prop" : { "x" : 1976, "y" : 187, "width" : 126, "height" : 35 }, "textPosition" : { "x" : 1991, "y" : 187 }, "bgColor" : { "r" : 204, "g" : 255, "b" : 255 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 2102, "y" : 187 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 2102, "y" : 187 } } }, "connectors" : [ { "edgeId" : 74156, "type" : "OUTPUT", "segments" : [ ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 74158, "reactomeId" : 10028048, "displayName" : "SH2B family", "schemaClass" : "DefinedSet", "renderableClass" : "EntitySet", "position" : { "x" : 1876, "y" : 240 }, "minX" : 1836, "maxX" : 1931, "minY" : 204, "maxY" : 251, "prop" : { "x" : 1836, "y" : 229, "width" : 81, "height" : 22 }, "textPosition" : { "x" : 1836, "y" : 229 }, "connectors" : [ { "edgeId" : 74156, "type" : "INPUT", "segments" : [ { "from" : { "x" : 1892, "y" : 223 }, "to" : { "x" : 1931, "y" : 204 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 74161, "reactomeId" : 113573, "displayName" : "GTP", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 1579, "y" : 132 }, "minX" : 1561, "maxX" : 1626, "minY" : 117, "maxY" : 159, "prop" : { "x" : 1561, "y" : 118, "width" : 37, "height" : 29 }, "textPosition" : { "x" : 1563, "y" : 122 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1593, "y" : 123 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1593, "y" : 123 } } }, "connectors" : [ { "edgeId" : 74160, "type" : "INPUT", "segments" : [ { "from" : { "x" : 1601, "y" : 142 }, "to" : { "x" : 1626, "y" : 159 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 74163, "reactomeId" : 113581, "displayName" : "ADP", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 1749, "y" : 140 }, "minX" : 1693, "maxX" : 1770, "minY" : 125, "maxY" : 161, "prop" : { "x" : 1730, "y" : 126, "width" : 39, "height" : 29 }, "textPosition" : { "x" : 1733, "y" : 130 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1764, "y" : 131 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1764, "y" : 131 } } }, "connectors" : [ { "edgeId" : 74160, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 1727, "y" : 147 }, "to" : { "x" : 1693, "y" : 161 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 1722, "y" : 153 }, "b" : { "x" : 1727, "y" : 147 }, "c" : { "x" : 1719, "y" : 146 }, "type" : "ARROW", "centre" : { "x" : 1719, "y" : 146 } } } ] }, { "id" : 74162, "reactomeId" : 159448, "displayName" : "AMP", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 1568, "y" : 206 }, "minX" : 1513, "maxX" : 1626, "minY" : 159, "maxY" : 228, "prop" : { "x" : 1513, "y" : 184, "width" : 110, "height" : 44 }, "textPosition" : { "x" : 1551, "y" : 195 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1618, "y" : 189 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1618, "y" : 189 } } }, "connectors" : [ { "edgeId" : 74160, "type" : "INPUT", "segments" : [ { "from" : { "x" : 1595, "y" : 181 }, "to" : { "x" : 1626, "y" : 159 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 74165, "reactomeId" : 10028117, "displayName" : "AK3", "schemaClass" : "EntityWithAccessionedSequence", "renderableClass" : "Protein", "position" : { "x" : 1667, "y" : 109 }, "minX" : 1640, "maxX" : 1700, "minY" : 93, "maxY" : 153, "prop" : { "x" : 1640, "y" : 99, "width" : 54, "height" : 20 }, "textPosition" : { "x" : 1651, "y" : 99 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1694, "y" : 99 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1694, "y" : 99 } } }, "connectors" : [ { "edgeId" : 74160, "type" : "CATALYST", "segments" : [ { "from" : { "x" : 1667, "y" : 122 }, "to" : { "x" : 1667, "y" : 145 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "c" : { "x" : 1667, "y" : 149 }, "r" : 4, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1667, "y" : 149 } } } ] }, { "id" : 74164, "reactomeId" : 113525, "displayName" : "GDP", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 1747, "y" : 196 }, "minX" : 1693, "maxX" : 1768, "minY" : 161, "maxY" : 211, "prop" : { "x" : 1728, "y" : 182, "width" : 39, "height" : 29 }, "textPosition" : { "x" : 1730, "y" : 186 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1762, "y" : 187 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1762, "y" : 187 } } }, "connectors" : [ { "edgeId" : 74160, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 1725, "y" : 183 }, "to" : { "x" : 1693, "y" : 161 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 1717, "y" : 182 }, "b" : { "x" : 1725, "y" : 183 }, "c" : { "x" : 1722, "y" : 176 }, "type" : "ARROW", "centre" : { "x" : 1722, "y" : 176 } } } ] }, { "id" : 74167, "reactomeId" : 1008228, "displayName" : "Promotor region of beta-globin", "schemaClass" : "OtherEntity", "renderableClass" : "Entity", "position" : { "x" : 930, "y" : 519 }, "minX" : 871, "maxX" : 989, "minY" : 502, "maxY" : 583, "prop" : { "x" : 871, "y" : 502, "width" : 118, "height" : 35 }, "textPosition" : { "x" : 873, "y" : 502 }, "connectors" : [ { "edgeId" : 74166, "type" : "INPUT", "segments" : [ { "from" : { "x" : 916, "y" : 540 }, "to" : { "x" : 879, "y" : 583 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 74169, "reactomeId" : 10028111, "displayName" : "NF-E2:Promoter region of beta-globin", "schemaClass" : "Complex", "renderableClass" : "Complex", "position" : { "x" : 883, "y" : 680 }, "minX" : 820, "maxX" : 952, "minY" : 649, "maxY" : 706, "prop" : { "x" : 820, "y" : 655, "width" : 126, "height" : 51 }, "textPosition" : { "x" : 828, "y" : 657 }, "bgColor" : { "r" : 204, "g" : 255, "b" : 255 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 946, "y" : 655 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 946, "y" : 655 } } }, "connectors" : [ { "edgeId" : 74166, "type" : "OUTPUT", "segments" : [ ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 74168, "reactomeId" : 10028109, "displayName" : "NF-E2", "schemaClass" : "Complex", "renderableClass" : "Complex", "position" : { "x" : 825, "y" : 517 }, "minX" : 797, "maxX" : 879, "minY" : 500, "maxY" : 583, "prop" : { "x" : 797, "y" : 506, "width" : 57, "height" : 23 }, "textPosition" : { "x" : 803, "y" : 508 }, "bgColor" : { "r" : 204, "g" : 255, "b" : 255 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 854, "y" : 506 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 854, "y" : 506 } } }, "connectors" : [ { "edgeId" : 74166, "type" : "INPUT", "segments" : [ { "from" : { "x" : 834, "y" : 532 }, "to" : { "x" : 879, "y" : 583 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 74171, "reactomeId" : 10028134, "displayName" : "C-terminal EH domain containing proteins", "schemaClass" : "DefinedSet", "renderableClass" : "EntitySet", "position" : { "x" : 1212, "y" : 122 }, "minX" : 1148, "maxX" : 1277, "minY" : 97, "maxY" : 165, "prop" : { "x" : 1148, "y" : 97, "width" : 129, "height" : 50 }, "textPosition" : { "x" : 1148, "y" : 97 }, "connectors" : [ { "edgeId" : 74170, "type" : "INPUT", "segments" : [ { "from" : { "x" : 1231, "y" : 153 }, "to" : { "x" : 1246, "y" : 165 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 74173, "reactomeId" : 10028136, "displayName" : "C-terminal EH domain containing proteins:Rabenosyn-5", "schemaClass" : "Complex", "renderableClass" : "Complex", "position" : { "x" : 1380, "y" : 167 }, "minX" : 1318, "maxX" : 1448, "minY" : 130, "maxY" : 199, "prop" : { "x" : 1318, "y" : 136, "width" : 124, "height" : 63 }, "textPosition" : { "x" : 1316, "y" : 136 }, "bgColor" : { "r" : 204, "g" : 255, "b" : 255 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1442, "y" : 136 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1442, "y" : 136 } } }, "connectors" : [ { "edgeId" : 74170, "type" : "OUTPUT", "segments" : [ ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 74172, "reactomeId" : 10000376, "displayName" : "ZFYVE20", "schemaClass" : "EntityWithAccessionedSequence", "renderableClass" : "Protein", "position" : { "x" : 1211, "y" : 215 }, "minX" : 1165, "maxX" : 1264, "minY" : 165, "maxY" : 276, "prop" : { "x" : 1165, "y" : 205, "width" : 93, "height" : 21 }, "textPosition" : { "x" : 1180, "y" : 205 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1258, "y" : 205 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1258, "y" : 205 } } }, "connectors" : [ { "edgeId" : 74170, "type" : "INPUT", "segments" : [ { "from" : { "x" : 1218, "y" : 202 }, "to" : { "x" : 1246, "y" : 165 } } ], "stoichiometry" : { "value" : 1 } }, { "edgeId" : 74174, "type" : "INPUT", "segments" : [ { "from" : { "x" : 1216, "y" : 229 }, "to" : { "x" : 1245, "y" : 276 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 74175, "reactomeId" : 10028189, "displayName" : "RAB5A", "schemaClass" : "EntityWithAccessionedSequence", "renderableClass" : "Protein", "position" : { "x" : 1171, "y" : 279 }, "minX" : 1133, "maxX" : 1245, "minY" : 261, "maxY" : 292, "prop" : { "x" : 1133, "y" : 267, "width" : 76, "height" : 25 }, "textPosition" : { "x" : 1147, "y" : 269 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1209, "y" : 267 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1209, "y" : 267 } } }, "connectors" : [ { "edgeId" : 74174, "type" : "INPUT", "segments" : [ { "from" : { "x" : 1212, "y" : 277 }, "to" : { "x" : 1245, "y" : 276 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 74177, "reactomeId" : 10028195, "displayName" : "Rabenosyn-5:VPS-45", "schemaClass" : "Complex", "renderableClass" : "Complex", "position" : { "x" : 1384, "y" : 277 }, "minX" : 1337, "maxX" : 1437, "minY" : 253, "maxY" : 296, "prop" : { "x" : 1337, "y" : 259, "width" : 94, "height" : 37 }, "textPosition" : { "x" : 1337, "y" : 261 }, "bgColor" : { "r" : 204, "g" : 255, "b" : 255 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1431, "y" : 259 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1431, "y" : 259 } } }, "connectors" : [ { "edgeId" : 74174, "type" : "OUTPUT", "segments" : [ ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 74176, "reactomeId" : 10028193, "displayName" : "Vps45", "schemaClass" : "EntityWithAccessionedSequence", "renderableClass" : "Protein", "position" : { "x" : 1189, "y" : 340 }, "minX" : 1154, "maxX" : 1245, "minY" : 276, "maxY" : 356, "prop" : { "x" : 1154, "y" : 324, "width" : 70, "height" : 32 }, "textPosition" : { "x" : 1165, "y" : 329 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1224, "y" : 324 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1224, "y" : 324 } } }, "connectors" : [ { "edgeId" : 74174, "type" : "INPUT", "segments" : [ { "from" : { "x" : 1203, "y" : 321 }, "to" : { "x" : 1245, "y" : 276 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 74179, "reactomeId" : 10028179, "displayName" : "DOCK-GEFs", "schemaClass" : "CandidateSet", "renderableClass" : "EntitySet", "position" : { "x" : 1858, "y" : 75 }, "minX" : 1826, "maxX" : 1929, "minY" : 61, "maxY" : 96, "prop" : { "x" : 1826, "y" : 61, "width" : 65, "height" : 29 }, "textPosition" : { "x" : 1836, "y" : 58 }, "connectors" : [ { "edgeId" : 74178, "type" : "INPUT", "segments" : [ { "from" : { "x" : 1897, "y" : 84 }, "to" : { "x" : 1929, "y" : 96 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 74181, "reactomeId" : 10028183, "displayName" : "DOCK-GEFs:RAC1, CDC42", "schemaClass" : "Complex", "renderableClass" : "Complex", "position" : { "x" : 2036, "y" : 94 }, "minX" : 1978, "maxX" : 2100, "minY" : 71, "maxY" : 112, "prop" : { "x" : 1978, "y" : 77, "width" : 116, "height" : 35 }, "textPosition" : { "x" : 1976, "y" : 77 }, "bgColor" : { "r" : 204, "g" : 255, "b" : 255 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 2094, "y" : 77 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 2094, "y" : 77 } } }, "connectors" : [ { "edgeId" : 74178, "type" : "OUTPUT", "segments" : [ ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 74180, "reactomeId" : 10028181, "displayName" : "RAC1, CDC42", "schemaClass" : "DefinedSet", "renderableClass" : "EntitySet", "position" : { "x" : 1862, "y" : 123 }, "minX" : 1833, "maxX" : 1929, "minY" : 96, "maxY" : 140, "prop" : { "x" : 1833, "y" : 106, "width" : 59, "height" : 34 }, "textPosition" : { "x" : 1838, "y" : 106 }, "connectors" : [ { "edgeId" : 74178, "type" : "INPUT", "segments" : [ { "from" : { "x" : 1898, "y" : 111 }, "to" : { "x" : 1929, "y" : 96 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 74183, "reactomeId" : 113592, "displayName" : "ATP", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 1617, "y" : 533 }, "minX" : 1597, "maxX" : 1642, "minY" : 494, "maxY" : 548, "prop" : { "x" : 1597, "y" : 518, "width" : 40, "height" : 30 }, "textPosition" : { "x" : 1601, "y" : 522 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1632, "y" : 523 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1632, "y" : 523 } } }, "connectors" : [ { "edgeId" : 74182, "type" : "INPUT", "segments" : [ { "from" : { "x" : 1626, "y" : 515 }, "to" : { "x" : 1642, "y" : 494 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 74185, "reactomeId" : 29370, "displayName" : "ADP", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 1722, "y" : 533 }, "minX" : 1698, "maxX" : 1744, "minY" : 495, "maxY" : 548, "prop" : { "x" : 1702, "y" : 518, "width" : 41, "height" : 30 }, "textPosition" : { "x" : 1706, "y" : 522 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1738, "y" : 523 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1738, "y" : 523 } } }, "connectors" : [ { "edgeId" : 74182, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 1712, "y" : 515 }, "to" : { "x" : 1698, "y" : 495 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 1705, "y" : 512 }, "b" : { "x" : 1712, "y" : 515 }, "c" : { "x" : 1711, "y" : 507 }, "type" : "ARROW", "centre" : { "x" : 1711, "y" : 507 } } } ] }, { "id" : 74184, "reactomeId" : 994146, "displayName" : "I(1,3,4,6)P4", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 1762, "y" : 483 }, "minX" : 1698, "maxX" : 1805, "minY" : 467, "maxY" : 498, "prop" : { "x" : 1720, "y" : 468, "width" : 84, "height" : 30 }, "textPosition" : { "x" : 1721, "y" : 472 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1799, "y" : 473 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1799, "y" : 473 } } }, "connectors" : [ { "edgeId" : 74182, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 1717, "y" : 490 }, "to" : { "x" : 1698, "y" : 495 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 1711, "y" : 496 }, "b" : { "x" : 1717, "y" : 490 }, "c" : { "x" : 1709, "y" : 488 }, "type" : "ARROW", "centre" : { "x" : 1709, "y" : 488 } } } ] }, { "id" : 74204, "reactomeId" : 10100559, "displayName" : "Kinesins", "schemaClass" : "Pathway", "renderableClass" : "ProcessNode", "position" : { "x" : 1972, "y" : 362 }, "minX" : 1913, "maxX" : 2031, "minY" : 330, "maxY" : 395, "prop" : { "x" : 1913, "y" : 330, "width" : 118, "height" : 65 }, "textPosition" : { "x" : 1938, "y" : 348 }, "connectors" : [ ] } ], "edges" : [ { "id" : 74144, "reactomeId" : 10028016, "displayName" : "REST recruits the BHC complex", "schemaClass" : "Reaction", "renderableClass" : "Reaction", "position" : { "x" : 195, "y" : 895 }, "minX" : 177, "maxX" : 234, "minY" : 889, "maxY" : 901, "reactionType" : "binding", "segments" : [ { "from" : { "x" : 177, "y" : 896 }, "to" : { "x" : 195, "y" : 895 } }, { "from" : { "x" : 195, "y" : 895 }, "to" : { "x" : 234, "y" : 895 } } ], "endShape" : { "a" : { "x" : 227, "y" : 899 }, "b" : { "x" : 234, "y" : 895 }, "c" : { "x" : 227, "y" : 891 }, "type" : "ARROW", "centre" : { "x" : 227, "y" : 891 } }, "reactionShape" : { "c" : { "x" : 195, "y" : 895 }, "r" : 5, "type" : "CIRCLE", "centre" : { "x" : 195, "y" : 895 } }, "inputs" : [ { "id" : 74145, "points" : [ { "x" : 158, "y" : 887 } ] }, { "id" : 74146, "points" : [ { "x" : 136, "y" : 915 } ] } ], "outputs" : [ { "id" : 74147 } ] }, { "id" : 74178, "reactomeId" : 10028185, "displayName" : "DOCKs bind to RhoGEFs", "schemaClass" : "Reaction", "renderableClass" : "Reaction", "position" : { "x" : 1942, "y" : 95 }, "minX" : 1929, "maxX" : 1975, "minY" : 89, "maxY" : 101, "reactionType" : "binding", "segments" : [ { "from" : { "x" : 1929, "y" : 96 }, "to" : { "x" : 1942, "y" : 95 } }, { "from" : { "x" : 1942, "y" : 95 }, "to" : { "x" : 1975, "y" : 94 } } ], "endShape" : { "a" : { "x" : 1968, "y" : 98 }, "b" : { "x" : 1975, "y" : 94 }, "c" : { "x" : 1968, "y" : 90 }, "type" : "ARROW", "centre" : { "x" : 1968, "y" : 90 } }, "reactionShape" : { "c" : { "x" : 1942, "y" : 95 }, "r" : 5, "type" : "CIRCLE", "centre" : { "x" : 1942, "y" : 95 } }, "inputs" : [ { "id" : 74179, "points" : [ { "x" : 1897, "y" : 84 } ] }, { "id" : 74180, "points" : [ { "x" : 1898, "y" : 111 } ] } ], "outputs" : [ { "id" : 74181 } ] }, { "id" : 74117, "reactomeId" : 10027245, "displayName" : "RAD51B binds RAD51C", "schemaClass" : "Reaction", "renderableClass" : "Reaction", "position" : { "x" : 473, "y" : 93 }, "minX" : 435, "maxX" : 517, "minY" : 86, "maxY" : 98, "reactionType" : "binding", "segments" : [ { "from" : { "x" : 435, "y" : 94 }, "to" : { "x" : 473, "y" : 93 } }, { "from" : { "x" : 473, "y" : 93 }, "to" : { "x" : 511, "y" : 92 } } ], "endShape" : { "a" : { "x" : 504, "y" : 96 }, "b" : { "x" : 511, "y" : 92 }, "c" : { "x" : 504, "y" : 88 }, "type" : "ARROW", "centre" : { "x" : 504, "y" : 88 } }, "reactionShape" : { "c" : { "x" : 473, "y" : 93 }, "r" : 5, "type" : "CIRCLE", "centre" : { "x" : 473, "y" : 93 } }, "inputs" : [ { "id" : 74118, "points" : [ { "x" : 413, "y" : 108 } ] }, { "id" : 74119, "points" : [ { "x" : 412, "y" : 83 } ] } ], "outputs" : [ { "id" : 74120 } ] }, { "id" : 74148, "reactomeId" : 10028042, "displayName" : "ZFPM proteins bind GATA proteins", "schemaClass" : "Reaction", "renderableClass" : "Reaction", "position" : { "x" : 515, "y" : 891 }, "minX" : 489, "maxX" : 551, "minY" : 885, "maxY" : 897, "reactionType" : "binding", "segments" : [ { "from" : { "x" : 489, "y" : 892 }, "to" : { "x" : 515, "y" : 891 } }, { "from" : { "x" : 515, "y" : 891 }, "to" : { "x" : 551, "y" : 891 } } ], "endShape" : { "a" : { "x" : 544, "y" : 895 }, "b" : { "x" : 551, "y" : 891 }, "c" : { "x" : 544, "y" : 887 }, "type" : "ARROW", "centre" : { "x" : 544, "y" : 887 } }, "reactionShape" : { "c" : { "x" : 515, "y" : 891 }, "r" : 5, "type" : "CIRCLE", "centre" : { "x" : 515, "y" : 891 } }, "inputs" : [ { "id" : 74149, "points" : [ { "x" : 465, "y" : 901 } ] }, { "id" : 74150, "points" : [ { "x" : 462, "y" : 883 } ] } ], "outputs" : [ { "id" : 74151 } ] }, { "id" : 74182, "reactomeId" : 10044026, "displayName" : "ITPK1 converts Ins-1,3,4-P3 to Ins-1,3,4,6-P4", "schemaClass" : "Reaction", "renderableClass" : "Reaction", "position" : { "x" : 1678, "y" : 495 }, "minX" : 1642, "maxX" : 1698, "minY" : 489, "maxY" : 501, "reactionType" : "transition", "segments" : [ { "from" : { "x" : 1642, "y" : 494 }, "to" : { "x" : 1678, "y" : 495 } }, { "from" : { "x" : 1678, "y" : 495 }, "to" : { "x" : 1698, "y" : 495 } } ], "reactionShape" : { "a" : { "x" : 1672, "y" : 489 }, "b" : { "x" : 1684, "y" : 501 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 1678, "y" : 495 } }, "inputs" : [ { "id" : 74183, "points" : [ { "x" : 1626, "y" : 515 } ] }, { "id" : 74142, "points" : [ { "x" : 1613, "y" : 482 } ] } ], "outputs" : [ { "id" : 74184, "points" : [ { "x" : 1717, "y" : 490 } ] }, { "id" : 74185, "points" : [ { "x" : 1712, "y" : 515 } ] } ], "catalysts" : [ { "id" : 74140, "points" : [ { "x" : 1670, "y" : 402 } ] } ] }, { "id" : 74121, "reactomeId" : 10027084, "displayName" : "RAD51B:RAD51C binds single-stranded DNA", "schemaClass" : "Reaction", "renderableClass" : "Reaction", "position" : { "x" : 693, "y" : 147 }, "minX" : 660, "maxX" : 742, "minY" : 141, "maxY" : 153, "reactionType" : "binding", "segments" : [ { "from" : { "x" : 660, "y" : 148 }, "to" : { "x" : 693, "y" : 147 } }, { "from" : { "x" : 693, "y" : 147 }, "to" : { "x" : 742, "y" : 146 } } ], "endShape" : { "a" : { "x" : 735, "y" : 150 }, "b" : { "x" : 742, "y" : 146 }, "c" : { "x" : 735, "y" : 142 }, "type" : "ARROW", "centre" : { "x" : 735, "y" : 142 } }, "reactionShape" : { "c" : { "x" : 693, "y" : 147 }, "r" : 5, "type" : "CIRCLE", "centre" : { "x" : 693, "y" : 147 } }, "inputs" : [ { "id" : 74122, "points" : [ { "x" : 622, "y" : 154 } ] }, { "id" : 74120, "points" : [ { "x" : 587, "y" : 112 } ] } ], "outputs" : [ { "id" : 74123 } ] }, { "id" : 74152, "reactomeId" : 10028065, "displayName" : "JMJD1C demethylates H3K9 mono- and di-methylation", "schemaClass" : "Reaction", "renderableClass" : "Reaction", "position" : { "x" : 239, "y" : 663 }, "minX" : 219, "maxX" : 263, "minY" : 657, "maxY" : 669, "reactionType" : "transition", "segments" : [ { "from" : { "x" : 219, "y" : 663 }, "to" : { "x" : 239, "y" : 663 } }, { "from" : { "x" : 239, "y" : 663 }, "to" : { "x" : 263, "y" : 663 } } ], "endShape" : { "a" : { "x" : 256, "y" : 667 }, "b" : { "x" : 263, "y" : 663 }, "c" : { "x" : 256, "y" : 659 }, "type" : "ARROW", "centre" : { "x" : 256, "y" : 659 } }, "reactionShape" : { "a" : { "x" : 233, "y" : 657 }, "b" : { "x" : 245, "y" : 669 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 239, "y" : 663 } }, "inputs" : [ { "id" : 74153 } ], "outputs" : [ { "id" : 74154 } ], "catalysts" : [ { "id" : 74155, "points" : [ { "x" : 239, "y" : 706 } ] } ] }, { "id" : 74124, "reactomeId" : 10027954, "displayName" : "Dual-specific AKAPs bind type I and II PKA regulatory subunits", "schemaClass" : "Reaction", "renderableClass" : "Reaction", "position" : { "x" : 1931, "y" : 540 }, "minX" : 1914, "maxX" : 1991, "minY" : 534, "maxY" : 546, "reactionType" : "binding", "segments" : [ { "from" : { "x" : 1914, "y" : 541 }, "to" : { "x" : 1931, "y" : 540 } }, { "from" : { "x" : 1931, "y" : 540 }, "to" : { "x" : 1991, "y" : 540 } } ], "endShape" : { "a" : { "x" : 1984, "y" : 544 }, "b" : { "x" : 1991, "y" : 540 }, "c" : { "x" : 1984, "y" : 536 }, "type" : "ARROW", "centre" : { "x" : 1984, "y" : 536 } }, "reactionShape" : { "c" : { "x" : 1931, "y" : 540 }, "r" : 5, "type" : "CIRCLE", "centre" : { "x" : 1931, "y" : 540 } }, "inputs" : [ { "id" : 74125, "points" : [ { "x" : 1897, "y" : 521 } ] }, { "id" : 74126, "points" : [ { "x" : 1906, "y" : 556 } ] } ], "outputs" : [ { "id" : 74127 } ] }, { "id" : 74156, "reactomeId" : 10028054, "displayName" : "SH2B proteins bind JAK2", "schemaClass" : "Reaction", "renderableClass" : "Reaction", "position" : { "x" : 1948, "y" : 204 }, "minX" : 1931, "maxX" : 1973, "minY" : 198, "maxY" : 210, "reactionType" : "binding", "segments" : [ { "from" : { "x" : 1931, "y" : 204 }, "to" : { "x" : 1948, "y" : 204 } }, { "from" : { "x" : 1948, "y" : 204 }, "to" : { "x" : 1973, "y" : 204 } } ], "endShape" : { "a" : { "x" : 1966, "y" : 208 }, "b" : { "x" : 1973, "y" : 204 }, "c" : { "x" : 1966, "y" : 200 }, "type" : "ARROW", "centre" : { "x" : 1966, "y" : 200 } }, "reactionShape" : { "c" : { "x" : 1948, "y" : 204 }, "r" : 5, "type" : "CIRCLE", "centre" : { "x" : 1948, "y" : 204 } }, "inputs" : [ { "id" : 74157, "points" : [ { "x" : 1910, "y" : 199 } ] }, { "id" : 74158, "points" : [ { "x" : 1892, "y" : 223 } ] } ], "outputs" : [ { "id" : 74159 } ] }, { "id" : 74160, "reactomeId" : 10028120, "displayName" : "Adenylate Kinase 3 is a GTP-AMP phosphotransferase", "schemaClass" : "Reaction", "renderableClass" : "Reaction", "position" : { "x" : 1667, "y" : 161 }, "minX" : 1626, "maxX" : 1693, "minY" : 155, "maxY" : 167, "reactionType" : "transition", "segments" : [ { "from" : { "x" : 1626, "y" : 159 }, "to" : { "x" : 1667, "y" : 161 } }, { "from" : { "x" : 1667, "y" : 161 }, "to" : { "x" : 1693, "y" : 161 } } ], "reactionShape" : { "a" : { "x" : 1661, "y" : 155 }, "b" : { "x" : 1673, "y" : 167 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 1667, "y" : 161 } }, "inputs" : [ { "id" : 74161, "points" : [ { "x" : 1601, "y" : 142 } ] }, { "id" : 74162, "points" : [ { "x" : 1595, "y" : 181 } ] } ], "outputs" : [ { "id" : 74163, "points" : [ { "x" : 1727, "y" : 147 } ] }, { "id" : 74164, "points" : [ { "x" : 1725, "y" : 183 } ] } ], "catalysts" : [ { "id" : 74165, "points" : [ { "x" : 1667, "y" : 122 } ] } ] }, { "id" : 74128, "reactomeId" : 10027941, "displayName" : "Mitofusins trans-interact linking mitochondria prior to fusion", "schemaClass" : "Reaction", "renderableClass" : "Reaction", "position" : { "x" : 1634, "y" : 69 }, "minX" : 1586, "maxX" : 1662, "minY" : 63, "maxY" : 75, "reactionType" : "binding", "segments" : [ { "from" : { "x" : 1586, "y" : 69 }, "to" : { "x" : 1634, "y" : 69 } }, { "from" : { "x" : 1634, "y" : 69 }, "to" : { "x" : 1662, "y" : 69 } } ], "endShape" : { "a" : { "x" : 1655, "y" : 73 }, "b" : { "x" : 1662, "y" : 69 }, "c" : { "x" : 1655, "y" : 65 }, "type" : "ARROW", "centre" : { "x" : 1655, "y" : 65 } }, "reactionShape" : { "c" : { "x" : 1634, "y" : 69 }, "r" : 5, "type" : "CIRCLE", "centre" : { "x" : 1634, "y" : 69 } }, "inputs" : [ { "id" : 74129, "stoichiometry" : 2 } ], "outputs" : [ { "id" : 74130 } ] }, { "id" : 74131, "reactomeId" : 10027978, "displayName" : "HP1 alpha binds Histone H3K9(me)3", "schemaClass" : "Reaction", "renderableClass" : "Reaction", "position" : { "x" : 251, "y" : 553 }, "minX" : 223, "maxX" : 311, "minY" : 547, "maxY" : 559, "reactionType" : "binding", "segments" : [ { "from" : { "x" : 223, "y" : 554 }, "to" : { "x" : 251, "y" : 553 } }, { "from" : { "x" : 251, "y" : 553 }, "to" : { "x" : 311, "y" : 552 } } ], "endShape" : { "a" : { "x" : 304, "y" : 556 }, "b" : { "x" : 311, "y" : 552 }, "c" : { "x" : 304, "y" : 548 }, "type" : "ARROW", "centre" : { "x" : 304, "y" : 548 } }, "reactionShape" : { "c" : { "x" : 251, "y" : 553 }, "r" : 5, "type" : "CIRCLE", "centre" : { "x" : 251, "y" : 553 } }, "inputs" : [ { "id" : 74132, "points" : [ { "x" : 176, "y" : 530 } ] }, { "id" : 74133, "points" : [ { "x" : 198, "y" : 567 } ] } ], "outputs" : [ { "id" : 74134 } ] }, { "id" : 74135, "reactomeId" : 10027985, "displayName" : "ITPK1 converts Ins-3,4,5,6-P4 to Ins-1,3,4,5,6-P5", "schemaClass" : "Reaction", "renderableClass" : "Reaction", "position" : { "x" : 1670, "y" : 334 }, "minX" : 1645, "maxX" : 1697, "minY" : 328, "maxY" : 340, "reactionType" : "transition", "segments" : [ { "from" : { "x" : 1645, "y" : 333 }, "to" : { "x" : 1670, "y" : 334 } }, { "from" : { "x" : 1670, "y" : 334 }, "to" : { "x" : 1697, "y" : 333 } } ], "reactionShape" : { "a" : { "x" : 1664, "y" : 328 }, "b" : { "x" : 1676, "y" : 340 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 1670, "y" : 334 } }, "inputs" : [ { "id" : 74136, "points" : [ { "x" : 1615, "y" : 352 } ] }, { "id" : 74137, "points" : [ { "x" : 1613, "y" : 312 } ] } ], "outputs" : [ { "id" : 74138, "points" : [ { "x" : 1728, "y" : 355 } ] }, { "id" : 74139, "points" : [ { "x" : 1725, "y" : 312 } ] } ], "catalysts" : [ { "id" : 74140, "points" : [ { "x" : 1670, "y" : 369 } ] } ] }, { "id" : 74166, "reactomeId" : 10028113, "displayName" : "NFE2 binds the beta globin locus control region", "schemaClass" : "Reaction", "renderableClass" : "Reaction", "position" : { "x" : 881, "y" : 615 }, "minX" : 875, "maxX" : 887, "minY" : 583, "maxY" : 652, "reactionType" : "binding", "segments" : [ { "from" : { "x" : 879, "y" : 583 }, "to" : { "x" : 881, "y" : 615 } }, { "from" : { "x" : 881, "y" : 615 }, "to" : { "x" : 882, "y" : 652 } } ], "endShape" : { "a" : { "x" : 878, "y" : 645 }, "b" : { "x" : 882, "y" : 652 }, "c" : { "x" : 886, "y" : 645 }, "type" : "ARROW", "centre" : { "x" : 886, "y" : 645 } }, "reactionShape" : { "c" : { "x" : 881, "y" : 615 }, "r" : 5, "type" : "CIRCLE", "centre" : { "x" : 881, "y" : 615 } }, "inputs" : [ { "id" : 74167, "points" : [ { "x" : 916, "y" : 540 } ] }, { "id" : 74168, "points" : [ { "x" : 834, "y" : 532 } ] } ], "outputs" : [ { "id" : 74169 } ] }, { "id" : 74170, "reactomeId" : 10028138, "displayName" : "EHD proteins interact with Rabenosyn-5", "schemaClass" : "Reaction", "renderableClass" : "Reaction", "position" : { "x" : 1275, "y" : 166 }, "minX" : 1246, "maxX" : 1315, "minY" : 160, "maxY" : 172, "reactionType" : "binding", "segments" : [ { "from" : { "x" : 1246, "y" : 165 }, "to" : { "x" : 1275, "y" : 166 } }, { "from" : { "x" : 1275, "y" : 166 }, "to" : { "x" : 1315, "y" : 166 } } ], "endShape" : { "a" : { "x" : 1308, "y" : 170 }, "b" : { "x" : 1315, "y" : 166 }, "c" : { "x" : 1308, "y" : 162 }, "type" : "ARROW", "centre" : { "x" : 1308, "y" : 162 } }, "reactionShape" : { "c" : { "x" : 1275, "y" : 166 }, "r" : 5, "type" : "CIRCLE", "centre" : { "x" : 1275, "y" : 166 } }, "inputs" : [ { "id" : 74171, "points" : [ { "x" : 1231, "y" : 153 } ] }, { "id" : 74172, "points" : [ { "x" : 1218, "y" : 202 } ] } ], "outputs" : [ { "id" : 74173 } ] }, { "id" : 74141, "reactomeId" : 10027988, "displayName" : "ITPK1 converts Ins-1,3,4-P3 to Ins-1,3,4,5-P4", "schemaClass" : "Reaction", "renderableClass" : "Reaction", "position" : { "x" : 1662, "y" : 442 }, "minX" : 1638, "maxX" : 1680, "minY" : 436, "maxY" : 448, "reactionType" : "transition", "segments" : [ { "from" : { "x" : 1638, "y" : 443 }, "to" : { "x" : 1662, "y" : 442 } }, { "from" : { "x" : 1662, "y" : 442 }, "to" : { "x" : 1680, "y" : 442 } } ], "reactionShape" : { "a" : { "x" : 1656, "y" : 436 }, "b" : { "x" : 1668, "y" : 448 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 1662, "y" : 442 } }, "inputs" : [ { "id" : 74142, "points" : [ { "x" : 1616, "y" : 450 } ] }, { "id" : 74136, "points" : [ { "x" : 1601, "y" : 381 } ] } ], "outputs" : [ { "id" : 74143, "points" : [ { "x" : 1712, "y" : 442 } ] }, { "id" : 74138, "points" : [ { "x" : 1733, "y" : 390 } ] } ], "catalysts" : [ { "id" : 74140, "points" : [ { "x" : 1668, "y" : 402 } ] } ] }, { "id" : 74174, "reactomeId" : 10028197, "displayName" : "Rabenosyn-5 connects Rab5 to VPS-45", "schemaClass" : "Reaction", "renderableClass" : "Reaction", "position" : { "x" : 1271, "y" : 276 }, "minX" : 1245, "maxX" : 1334, "minY" : 270, "maxY" : 282, "reactionType" : "binding", "segments" : [ { "from" : { "x" : 1245, "y" : 276 }, "to" : { "x" : 1271, "y" : 276 } }, { "from" : { "x" : 1271, "y" : 276 }, "to" : { "x" : 1334, "y" : 276 } } ], "endShape" : { "a" : { "x" : 1327, "y" : 280 }, "b" : { "x" : 1334, "y" : 276 }, "c" : { "x" : 1327, "y" : 272 }, "type" : "ARROW", "centre" : { "x" : 1327, "y" : 272 } }, "reactionShape" : { "c" : { "x" : 1271, "y" : 276 }, "r" : 5, "type" : "CIRCLE", "centre" : { "x" : 1271, "y" : 276 } }, "inputs" : [ { "id" : 74175, "points" : [ { "x" : 1212, "y" : 277 } ] }, { "id" : 74172, "points" : [ { "x" : 1216, "y" : 229 } ] }, { "id" : 74176, "points" : [ { "x" : 1203, "y" : 321 } ] } ], "outputs" : [ { "id" : 74177 } ] } ], "compartments" : [ { "id" : 74197, "reactomeId" : 171907, "displayName" : "endosome lumen", "schemaClass" : "Compartment", "renderableClass" : "Compartment", "position" : { "x" : 1277, "y" : 237 }, "minX" : 1085, "maxX" : 1469, "minY" : 53, "maxY" : 421, "prop" : { "x" : 1085, "y" : 53, "width" : 384, "height" : 368 }, "textPosition" : { "x" : 1347, "y" : 384 }, "insets" : { "x" : 1095, "y" : 63, "width" : 364, "height" : 348 }, "bgColor" : { "r" : 250, "g" : 240, "b" : 240 }, "componentIds" : [ 74170, 74171, 74172, 74173, 74174, 74175, 74176, 74177 ] }, { "id" : 74187, "reactomeId" : 70101, "displayName" : "cytosol", "schemaClass" : "Compartment", "renderableClass" : "Compartment", "position" : { "x" : 1106, "y" : 505 }, "minX" : 0, "maxX" : 2213, "minY" : 0, "maxY" : 1010, "prop" : { "x" : 0, "y" : 0, "width" : 2213, "height" : 1010 }, "textPosition" : { "x" : 1302, "y" : 935 }, "insets" : { "x" : 10, "y" : 10, "width" : 2193, "height" : 990 }, "bgColor" : { "r" : 250, "g" : 240, "b" : 240 }, "componentIds" : [ 74124, 74125, 74126, 74127, 74186, 74188, 74135, 74138, 74139, 74140, 74136, 74137, 74141, 74142, 74156, 74157, 74158, 74159, 74197, 74178, 74179, 74180, 74181, 74128, 74204, 74143, 74182, 74183, 74184, 74185 ] }, { "id" : 74186, "reactomeId" : 7660, "displayName" : "nucleoplasm", "schemaClass" : "Compartment", "renderableClass" : "Compartment", "position" : { "x" : 532, "y" : 499 }, "minX" : 34, "maxX" : 1030, "minY" : 28, "maxY" : 971, "prop" : { "x" : 34, "y" : 28, "width" : 996, "height" : 943 }, "textPosition" : { "x" : 915, "y" : 920 }, "insets" : { "x" : 44, "y" : 38, "width" : 976, "height" : 923 }, "bgColor" : { "r" : 250, "g" : 240, "b" : 240 }, "componentIds" : [ 74117, 74118, 74119, 74120, 74122, 74121, 74123, 74131, 74132, 74133, 74134, 74144, 74145, 74147, 74149, 74150, 74151, 74148, 74152, 74153, 74154, 74155, 74168, 74166, 74167, 74169, 74210, 74211, 74146, 74212, 74213, 74214 ] }, { "id" : 74188, "reactomeId" : 5460, "displayName" : "mitochondrial matrix", "schemaClass" : "Compartment", "renderableClass" : "Compartment", "position" : { "x" : 1643, "y" : 161 }, "minX" : 1490, "maxX" : 1796, "minY" : 74, "maxY" : 249, "prop" : { "x" : 1490, "y" : 74, "width" : 306, "height" : 175 }, "textPosition" : { "x" : 1648, "y" : 213 }, "insets" : { "x" : 1500, "y" : 84, "width" : 286, "height" : 155 }, "bgColor" : { "r" : 250, "g" : 240, "b" : 240 }, "componentIds" : [ 74129, 74130, 74160, 74161, 74162, 74163, 74164, 74165 ] } ], "notes" : [ ], "links" : [ { "id" : 74211, "renderableClass" : "EntitySetAndMemberLink", "position" : { "x" : 243, "y" : 619 }, "minX" : 198, "maxX" : 288, "minY" : 603, "maxY" : 636, "segments" : [ { "from" : { "x" : 198, "y" : 603 }, "to" : { "x" : 288, "y" : 636 } } ], "reactionShape" : { "a" : { "x" : 237, "y" : 613 }, "b" : { "x" : 249, "y" : 625 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 243, "y" : 619 } }, "inputs" : [ { "id" : 74133 } ], "outputs" : [ { "id" : 74154 } ] }, { "id" : 74210, "renderableClass" : "EntitySetAndMemberLink", "position" : { "x" : 145, "y" : 628 }, "minX" : 139, "maxX" : 151, "minY" : 619, "maxY" : 637, "segments" : [ { "from" : { "x" : 145, "y" : 619 }, "to" : { "x" : 145, "y" : 637 } } ], "reactionShape" : { "a" : { "x" : 139, "y" : 622 }, "b" : { "x" : 151, "y" : 634 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 145, "y" : 628 } }, "inputs" : [ { "id" : 74133 } ], "outputs" : [ { "id" : 74153 } ] }, { "id" : 74212, "renderableClass" : "EntitySetAndEntitySetLink", "position" : { "x" : 241, "y" : 663 }, "minX" : 219, "maxX" : 263, "minY" : 657, "maxY" : 669, "segments" : [ { "from" : { "x" : 263, "y" : 663 }, "to" : { "x" : 219, "y" : 663 } } ], "reactionShape" : { "a" : { "x" : 235, "y" : 657 }, "b" : { "x" : 247, "y" : 669 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 241, "y" : 663 } }, "inputs" : [ { "id" : 74154 } ], "outputs" : [ { "id" : 74153 } ] } ], "shadows" : [ ], "minX" : 0, "maxX" : 2213, "minY" : 0, "maxY" : 1010, "disease" : false }