{
  "dbId" : 10100489,
  "stId" : "R-MMU-909733",
  "speciesName" : "Mus musculus",
  "nodes" : [ {
    "dbId" : 10021528,
    "stId" : "R-MMU-909693",
    "displayName" : "p-STAT2:p-STAT1 [nucleoplasm]",
    "schemaClass" : "Complex",
    "speciesId" : 48892,
    "parents" : [ 10021532 ],
    "children" : [ 10021526, 10021522 ]
  }, {
    "dbId" : 10021530,
    "stId" : "R-MMU-913522",
    "displayName" : "Irf9 [nucleoplasm]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48892,
    "identifier" : "Q61179",
    "standardIdentifier" : "uniprot:Q61179",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Irf9" ],
    "parents" : [ 10021532 ],
    "children" : [ ]
  }, {
    "dbId" : 10021532,
    "stId" : "R-MMU-913527",
    "displayName" : "ISGF3 [nucleoplasm]",
    "schemaClass" : "Complex",
    "speciesId" : 48892,
    "diagramIds" : [ 76065 ],
    "parents" : [ ],
    "children" : [ 10021530, 10021528 ]
  }, {
    "dbId" : 9696149,
    "stId" : "R-ALL-9696149",
    "displayName" : "recombinant IFNB1a [extracellular region]",
    "schemaClass" : "ProteinDrug",
    "speciesId" : 0,
    "identifier" : "8339",
    "standardIdentifier" : "iuphar.ligand:8339",
    "parents" : [ 9696187 ],
    "children" : [ ]
  }, {
    "dbId" : 10021520,
    "stId" : "R-MMU-9710965",
    "displayName" : "ISGF3:KPNA1:KPNB1 [cytosol]",
    "schemaClass" : "Complex",
    "speciesId" : 48892,
    "diagramIds" : [ 76064 ],
    "parents" : [ 10090863 ],
    "children" : [ 2065541, 10021518 ]
  }, {
    "dbId" : 10021522,
    "stId" : "R-MMU-909676",
    "displayName" : "phospho-Stat1 [nucleoplasm]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48892,
    "identifier" : "P42225",
    "standardIdentifier" : "uniprot:P42225",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Stat1" ],
    "parents" : [ 10021528 ],
    "children" : [ ]
  }, {
    "dbId" : 10021524,
    "stId" : "R-MMU-909684",
    "displayName" : "phospho-Stat1 [nucleoplasm]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48892,
    "identifier" : "P42225",
    "standardIdentifier" : "uniprot:P42225",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Stat1" ],
    "parents" : [ 10021687 ],
    "children" : [ ]
  }, {
    "dbId" : 10021526,
    "stId" : "R-MMU-909673",
    "displayName" : "phospho-Stat2 [nucleoplasm]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48892,
    "identifier" : "Q9WVL2",
    "standardIdentifier" : "uniprot:Q9WVL2",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Stat2" ],
    "parents" : [ 10021528 ],
    "children" : [ ]
  }, {
    "dbId" : 9954438,
    "stId" : "R-MMU-9954438",
    "displayName" : "Kpna1 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48892,
    "diagramIds" : [ 76105 ],
    "identifier" : "Q60960",
    "standardIdentifier" : "uniprot:Q60960",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Kpna1", "Rch2" ],
    "parents" : [ 10021685, 10090857, 10021518 ],
    "children" : [ ]
  }, {
    "dbId" : 10021514,
    "stId" : "R-MMU-909702",
    "displayName" : "p-STAT2:p-STAT1 [cytosol]",
    "schemaClass" : "Complex",
    "speciesId" : 48892,
    "diagramIds" : [ 76059 ],
    "parents" : [ 10021516, 10021536 ],
    "children" : [ 10020932, 10021464 ]
  }, {
    "dbId" : 10021516,
    "stId" : "R-MMU-909698",
    "displayName" : "ISGF3 [cytosol]",
    "schemaClass" : "Complex",
    "speciesId" : 48892,
    "diagramIds" : [ 76062 ],
    "parents" : [ 10090855, 10021518 ],
    "children" : [ 10021510, 10021514 ]
  }, {
    "dbId" : 10021518,
    "stId" : "R-MMU-9710958",
    "displayName" : "ISGF3:KPNA1 [cytosol]",
    "schemaClass" : "Complex",
    "speciesId" : 48892,
    "parents" : [ 10090859, 10021520 ],
    "children" : [ 10021516, 9954438 ]
  }, {
    "dbId" : 9678984,
    "stId" : "R-ALL-9678984",
    "displayName" : "JAK1,2 inhibitors [cytosol]",
    "schemaClass" : "DefinedSet",
    "speciesId" : 0,
    "diagramIds" : [ 76099 ],
    "parents" : [ 10021500 ],
    "children" : [ 9678829, 9717004, 9678779, 9678786 ]
  }, {
    "dbId" : 10021510,
    "stId" : "R-MMU-879183",
    "displayName" : "Irf9 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48892,
    "diagramIds" : [ 76061 ],
    "identifier" : "Q61179",
    "standardIdentifier" : "uniprot:Q61179",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Irf9" ],
    "parents" : [ 10021516 ],
    "children" : [ ]
  }, {
    "dbId" : 10021560,
    "stId" : "R-MMU-912684",
    "displayName" : "p-IFNAR1:p-TYK2:SOCS-1/SOCS-3 [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 48892,
    "parents" : [ 10021562 ],
    "children" : [ 10020900, 10021459, 10021454 ]
  }, {
    "dbId" : 10021562,
    "stId" : "R-MMU-912681",
    "displayName" : "p-TYK2:p-IFNAR1:SOCS-1/SOCS-3:IFNA/B:IFNAR2:p-JAK1:STAT2 [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 48892,
    "diagramIds" : [ 76044 ],
    "parents" : [ ],
    "children" : [ 10021483, 10021560 ]
  }, {
    "dbId" : 912682,
    "stId" : "R-MMU-912682",
    "displayName" : "Ifna1 [extracellular region]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48892,
    "identifier" : "P01572",
    "standardIdentifier" : "uniprot:P01572",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Ifna1" ],
    "parents" : [ 10021410 ],
    "children" : [ ]
  }, {
    "dbId" : 9696187,
    "stId" : "R-HSA-9696187",
    "displayName" : "type 1 interferon analogs [extracellular region]",
    "schemaClass" : "DefinedSet",
    "speciesId" : 48887,
    "diagramIds" : [ 76103 ],
    "parents" : [ 10021502 ],
    "children" : [ 9734377, 9696186, 9734435, 9734403, 9696149, 9734422, 9734438 ]
  }, {
    "dbId" : 9678779,
    "stId" : "R-ALL-9678779",
    "displayName" : "tofacitinib [cytosol]",
    "schemaClass" : "ChemicalDrug",
    "speciesId" : 0,
    "identifier" : "5677",
    "standardIdentifier" : "iuphar.ligand:5677",
    "chebiIdentifier" : "chebi:71200",
    "parents" : [ 9678619, 9678984 ],
    "children" : [ ]
  }, {
    "dbId" : 10006705,
    "stId" : "R-MMU-180714",
    "displayName" : "Kpnb1 [nucleoplasm]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48892,
    "diagramIds" : [ 76067 ],
    "identifier" : "P70168",
    "standardIdentifier" : "uniprot:P70168",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Kpnb1", "Impnb" ],
    "parents" : [ ],
    "children" : [ ]
  }, {
    "dbId" : 9696186,
    "stId" : "R-ALL-9696186",
    "displayName" : "recombinant IFNB1b [extracellular region]",
    "schemaClass" : "ProteinDrug",
    "speciesId" : 0,
    "identifier" : "8340",
    "standardIdentifier" : "iuphar.ligand:8340",
    "chebiIdentifier" : "chebi:5938",
    "parents" : [ 9696187 ],
    "children" : [ ]
  }, {
    "dbId" : 10021555,
    "stId" : "R-MMU-909707",
    "displayName" : "IFNAR1:p-TYK2 [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 48892,
    "parents" : [ 10021557 ],
    "children" : [ 10021542, 10021454 ]
  }, {
    "dbId" : 10021557,
    "stId" : "R-MMU-909705",
    "displayName" : "IFNA/B:IFNAR2:p-JAK1:STAT2:IFNAR1:p-TYK2 [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 48892,
    "diagramIds" : [ 76042 ],
    "parents" : [ ],
    "children" : [ 10021555, 10021483 ]
  }, {
    "dbId" : 10021544,
    "stId" : "R-MMU-909708",
    "displayName" : "IFNAR1:TYK2 [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 48892,
    "diagramIds" : [ 76037 ],
    "parents" : [ 10028078, 10021548, 10021546 ],
    "children" : [ 10021542, 10018050 ]
  }, {
    "dbId" : 10021546,
    "stId" : "R-MMU-909703",
    "displayName" : "IFNA/B:IFNAR2:JAK1:STAT2:IFNAR1:TYK2 [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 48892,
    "diagramIds" : [ 76038 ],
    "parents" : [ ],
    "children" : [ 10021498, 10021544 ]
  }, {
    "dbId" : 10021548,
    "stId" : "R-MMU-9678695",
    "displayName" : "IFNAR1:TYK2:TYK2 inhibitors [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 48892,
    "diagramIds" : [ 76039 ],
    "parents" : [ ],
    "children" : [ 9678619, 10021544 ]
  }, {
    "dbId" : 10006703,
    "stId" : "R-MMU-188865",
    "displayName" : "Kpna1 [nucleoplasm]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48892,
    "diagramIds" : [ 76066 ],
    "identifier" : "Q60960",
    "standardIdentifier" : "uniprot:Q60960",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Kpna1", "Rch2" ],
    "parents" : [ ],
    "children" : [ ]
  }, {
    "dbId" : 10021536,
    "stId" : "R-MMU-909712",
    "displayName" : "p-STAT2:p-STAT1:p-IFNAR1:p-TYK2 [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 48892,
    "parents" : [ 10021538 ],
    "children" : [ 10021459, 10021454, 10021514 ]
  }, {
    "dbId" : 10101923,
    "stId" : "R-MMU-9833482",
    "displayName" : "PKR-mediated signaling",
    "schemaClass" : "Pathway",
    "speciesId" : 48892,
    "diagramIds" : [ 76133 ]
  }, {
    "dbId" : 10021538,
    "stId" : "R-MMU-909711",
    "displayName" : "IFNA/B:IFNAR2:p-JAK1:STAT2:p-IFNAR1:p-TYK2:p-STAT2:p-STAT1 [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 48892,
    "diagramIds" : [ 76058 ],
    "parents" : [ ],
    "children" : [ 10021474, 10021536, 10021451 ]
  }, {
    "dbId" : 1169197,
    "stId" : "R-MMU-1169197",
    "displayName" : "Socs3 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48892,
    "identifier" : "O35718",
    "standardIdentifier" : "uniprot:O35718",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Socs3", "Cis3", "Cish3" ],
    "parents" : [ 10020900 ],
    "children" : [ ]
  }, {
    "dbId" : 10021542,
    "stId" : "R-MMU-877334",
    "displayName" : "Ifnar1 [plasma membrane]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48892,
    "identifier" : "P33896",
    "standardIdentifier" : "uniprot:P33896",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Ifnar1", "Ifar", "Ifnar" ],
    "parents" : [ 10021544, 10021555 ],
    "children" : [ ]
  }, {
    "dbId" : 940364,
    "stId" : "R-MMU-940364",
    "displayName" : "Ubiquitin (Ubb 1) [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48892,
    "identifier" : "P0CG49",
    "standardIdentifier" : "uniprot:P0CG49",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Ubb" ],
    "parents" : [ 9985374 ],
    "children" : [ ]
  }, {
    "dbId" : 940365,
    "stId" : "R-MMU-940365",
    "displayName" : "Ubiquitin (Uba52) [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48892,
    "identifier" : "P62984",
    "standardIdentifier" : "uniprot:P62984",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Uba52", "Ubcep2" ],
    "parents" : [ 9985374 ],
    "children" : [ ]
  }, {
    "dbId" : 940362,
    "stId" : "R-MMU-940362",
    "displayName" : "Ubiquitin (Ubc 3) [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48892,
    "identifier" : "P0CG50",
    "standardIdentifier" : "uniprot:P0CG50",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Ubc" ],
    "parents" : [ 9985374 ],
    "children" : [ ]
  }, {
    "dbId" : 940360,
    "stId" : "R-MMU-940360",
    "displayName" : "Ubiquitin (Ubc 5) [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48892,
    "identifier" : "P0CG50",
    "standardIdentifier" : "uniprot:P0CG50",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Ubc" ],
    "parents" : [ 9985374 ],
    "children" : [ ]
  }, {
    "dbId" : 10053072,
    "stId" : "R-MMU-5357403",
    "displayName" : "RNASEL dimer [mitochondrial matrix]",
    "schemaClass" : "Complex",
    "speciesId" : 48892,
    "diagramIds" : [ 76096 ],
    "parents" : [ 10053078 ],
    "children" : [ 10053070 ]
  }, {
    "dbId" : 940359,
    "stId" : "R-MMU-940359",
    "displayName" : "Ubiquitin (Ubc 4) [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48892,
    "identifier" : "P0CG50",
    "standardIdentifier" : "uniprot:P0CG50",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Ubc" ],
    "parents" : [ 9985374 ],
    "children" : [ ]
  }, {
    "dbId" : 10053076,
    "stId" : "R-MMU-5216010",
    "displayName" : "ABCE1 [mitochondrial matrix]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48892,
    "diagramIds" : [ 76095 ],
    "identifier" : "P61222",
    "standardIdentifier" : "uniprot:P61222",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 10053078 ],
    "children" : [ ]
  }, {
    "dbId" : 10053078,
    "stId" : "R-MMU-5223322",
    "displayName" : "ABCE1:RNASEL dimer [mitochondrial matrix]",
    "schemaClass" : "Complex",
    "speciesId" : 48892,
    "diagramIds" : [ 76097 ],
    "parents" : [ ],
    "children" : [ 10053076, 10053072 ]
  }, {
    "dbId" : 940382,
    "stId" : "R-MMU-940382",
    "displayName" : "Ubiquitin (Ubc 1) [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48892,
    "identifier" : "P0CG50",
    "standardIdentifier" : "uniprot:P0CG50",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Ubc" ],
    "parents" : [ 9985374 ],
    "children" : [ ]
  }, {
    "dbId" : 9678786,
    "stId" : "R-ALL-9678786",
    "displayName" : "ruxolitinib [cytosol]",
    "schemaClass" : "ChemicalDrug",
    "speciesId" : 0,
    "identifier" : "5688",
    "standardIdentifier" : "iuphar.ligand:5688",
    "chebiIdentifier" : "chebi:66919",
    "parents" : [ 9678619, 9678984 ],
    "children" : [ ]
  }, {
    "dbId" : 940379,
    "stId" : "R-MMU-940379",
    "displayName" : "Ubiquitin (Ubc 8) [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48892,
    "identifier" : "P0CG50",
    "standardIdentifier" : "uniprot:P0CG50",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Ubc" ],
    "parents" : [ 9985374 ],
    "children" : [ ]
  }, {
    "dbId" : 10053070,
    "stId" : "R-MMU-5223312",
    "displayName" : "Rnasel [mitochondrial matrix]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48892,
    "identifier" : "Q05921",
    "standardIdentifier" : "uniprot:Q05921",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Rnasel" ],
    "parents" : [ 10053072 ],
    "children" : [ ]
  }, {
    "dbId" : 940370,
    "stId" : "R-MMU-940370",
    "displayName" : "Ubiquitin (Pps27a) [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48892,
    "identifier" : "P62983",
    "standardIdentifier" : "uniprot:P62983",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Rps27a", "Uba80", "Ubcep1" ],
    "parents" : [ 9985374 ],
    "children" : [ ]
  }, {
    "dbId" : 940371,
    "stId" : "R-MMU-940371",
    "displayName" : "Ubiquitin (Ubc 7) [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48892,
    "identifier" : "P0CG50",
    "standardIdentifier" : "uniprot:P0CG50",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Ubc" ],
    "parents" : [ 9985374 ],
    "children" : [ ]
  }, {
    "dbId" : 10021368,
    "stId" : "R-MMU-877339-3",
    "displayName" : "Ifna7 [extracellular region]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48892,
    "identifier" : "P06799",
    "standardIdentifier" : "uniprot:P06799",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Ifna7" ],
    "parents" : [ 10021410 ],
    "children" : [ ]
  }, {
    "dbId" : 10021372,
    "stId" : "R-MMU-877339-4",
    "displayName" : "Ifna5 [extracellular region]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48892,
    "identifier" : "P07349",
    "standardIdentifier" : "uniprot:P07349",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Ifna5" ],
    "parents" : [ 10021410 ],
    "children" : [ ]
  }, {
    "dbId" : 940388,
    "stId" : "R-MMU-940388",
    "displayName" : "Ubiquitin (Ubc 2) [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48892,
    "identifier" : "P0CG50",
    "standardIdentifier" : "uniprot:P0CG50",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Ubc" ],
    "parents" : [ 9985374 ],
    "children" : [ ]
  }, {
    "dbId" : 10021364,
    "stId" : "R-MMU-877339-2",
    "displayName" : "Ifna2 [extracellular region]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48892,
    "identifier" : "P01573",
    "standardIdentifier" : "uniprot:P01573",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Ifna2" ],
    "parents" : [ 10021410 ],
    "children" : [ ]
  }, {
    "dbId" : 940386,
    "stId" : "R-MMU-940386",
    "displayName" : "Ubiquitin related 1 (Ubc r1) [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48892,
    "identifier" : "P0CG50",
    "standardIdentifier" : "uniprot:P0CG50",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Ubc" ],
    "parents" : [ 9985374 ],
    "children" : [ ]
  }, {
    "dbId" : 10021621,
    "stId" : "R-MMU-912325",
    "displayName" : "Usp18 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48892,
    "diagramIds" : [ 76077 ],
    "identifier" : "Q9WTV6",
    "standardIdentifier" : "uniprot:Q9WTV6",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Usp18" ],
    "parents" : [ 10021623 ],
    "children" : [ ]
  }, {
    "dbId" : 940384,
    "stId" : "R-MMU-940384",
    "displayName" : "Ubiquitin (Ubc 6) [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48892,
    "identifier" : "P0CG50",
    "standardIdentifier" : "uniprot:P0CG50",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Ubc" ],
    "parents" : [ 9985374 ],
    "children" : [ ]
  }, {
    "dbId" : 10021623,
    "stId" : "R-MMU-912690",
    "displayName" : "IFNAR2c:UBP43 [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 48892,
    "diagramIds" : [ 76079 ],
    "parents" : [ ],
    "children" : [ 10021621, 10021470 ]
  }, {
    "dbId" : 10021359,
    "stId" : "R-MMU-877339",
    "displayName" : "Ifnab [extracellular region]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48892,
    "identifier" : "L7MTU6",
    "standardIdentifier" : "uniprot:L7MTU6",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Ifnab" ],
    "parents" : [ 10021410 ],
    "children" : [ ]
  }, {
    "dbId" : 9734377,
    "stId" : "R-ALL-9734377",
    "displayName" : "recombinant IFNA2b [extracellular region]",
    "schemaClass" : "ProteinDrug",
    "speciesId" : 0,
    "identifier" : "8338",
    "standardIdentifier" : "iuphar.ligand:8338",
    "parents" : [ 9696187 ],
    "children" : [ ]
  }, {
    "dbId" : 9678829,
    "stId" : "R-ALL-9678829",
    "displayName" : "baricitinib [cytosol]",
    "schemaClass" : "ChemicalDrug",
    "speciesId" : 0,
    "identifier" : "7792",
    "standardIdentifier" : "iuphar.ligand:7792",
    "chebiIdentifier" : "chebi:95341",
    "parents" : [ 9678619, 9678984 ],
    "children" : [ ]
  }, {
    "dbId" : 10021400,
    "stId" : "R-MMU-877339-11",
    "displayName" : "Ifna13 [extracellular region]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48892,
    "identifier" : "Q80SU4",
    "standardIdentifier" : "uniprot:Q80SU4",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Ifna13" ],
    "parents" : [ 10021410 ],
    "children" : [ ]
  }, {
    "dbId" : 9734422,
    "stId" : "R-ALL-9734422",
    "displayName" : "peginterferon alfa-2b [extracellular region]",
    "schemaClass" : "ProteinDrug",
    "speciesId" : 0,
    "identifier" : "7462",
    "standardIdentifier" : "iuphar.ligand:7462",
    "parents" : [ 9696187 ],
    "children" : [ ]
  }, {
    "dbId" : 10021404,
    "stId" : "R-MMU-877339-12",
    "displayName" : "Ifna16 [extracellular region]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48892,
    "identifier" : "Q810G1",
    "standardIdentifier" : "uniprot:Q810G1",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Ifna16" ],
    "parents" : [ 10021410 ],
    "children" : [ ]
  }, {
    "dbId" : 10021392,
    "stId" : "R-MMU-877339-9",
    "displayName" : "Ifna15 [extracellular region]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48892,
    "identifier" : "Q61718",
    "standardIdentifier" : "uniprot:Q61718",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Ifna15" ],
    "parents" : [ 10021410 ],
    "children" : [ ]
  }, {
    "dbId" : 9678619,
    "stId" : "R-ALL-9678619",
    "displayName" : "TYK2 inhibitors [cytosol]",
    "schemaClass" : "DefinedSet",
    "speciesId" : 0,
    "diagramIds" : [ 76101 ],
    "parents" : [ 10021548 ],
    "children" : [ 9678829, 9678779, 9678786 ]
  }, {
    "dbId" : 10021396,
    "stId" : "R-MMU-877339-10",
    "displayName" : "Ifna12 [extracellular region]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48892,
    "identifier" : "Q80SS5",
    "standardIdentifier" : "uniprot:Q80SS5",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Ifna12" ],
    "parents" : [ 10021410 ],
    "children" : [ ]
  }, {
    "dbId" : 10006039,
    "stId" : "R-MMU-197938",
    "displayName" : "PTPN6 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48892,
    "diagramIds" : [ 76088 ],
    "identifier" : "P29351",
    "standardIdentifier" : "uniprot:P29351",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Ptpn6", "Hcp", "Hcph", "Ptp1C" ],
    "parents" : [ ],
    "children" : [ ]
  }, {
    "dbId" : 10021384,
    "stId" : "R-MMU-877339-7",
    "displayName" : "Ifna9 [extracellular region]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48892,
    "identifier" : "P09235",
    "standardIdentifier" : "uniprot:P09235",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Ifna9" ],
    "parents" : [ 10021410 ],
    "children" : [ ]
  }, {
    "dbId" : 10021388,
    "stId" : "R-MMU-877339-8",
    "displayName" : "Ifna11 [extracellular region]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48892,
    "identifier" : "Q61716",
    "standardIdentifier" : "uniprot:Q61716",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Ifna11" ],
    "parents" : [ 10021410 ],
    "children" : [ ]
  }, {
    "dbId" : 9734403,
    "stId" : "R-ALL-9734403",
    "displayName" : "recombinant IFNA2a [extracellular region]",
    "schemaClass" : "ProteinDrug",
    "speciesId" : 0,
    "identifier" : "4960",
    "standardIdentifier" : "iuphar.ligand:4960",
    "chebiIdentifier" : "chebi:5937",
    "parents" : [ 9696187 ],
    "children" : [ ]
  }, {
    "dbId" : 10021376,
    "stId" : "R-MMU-877339-5",
    "displayName" : "Ifna6 [extracellular region]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48892,
    "identifier" : "P07350",
    "standardIdentifier" : "uniprot:P07350",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Ifna6" ],
    "parents" : [ 10021410 ],
    "children" : [ ]
  }, {
    "dbId" : 9717004,
    "stId" : "R-ALL-9717004",
    "displayName" : "delgocitinib [cytosol]",
    "schemaClass" : "ChemicalDrug",
    "speciesId" : 0,
    "identifier" : "9619",
    "standardIdentifier" : "iuphar.ligand:9619",
    "chebiIdentifier" : "chebi:167600",
    "parents" : [ 9678984 ],
    "children" : [ ]
  }, {
    "dbId" : 2065541,
    "stId" : "R-MMU-2065541",
    "displayName" : "Importin subunit beta-1 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48892,
    "diagramIds" : [ 76109 ],
    "identifier" : "P70168",
    "standardIdentifier" : "uniprot:P70168",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Kpnb1", "Impnb" ],
    "parents" : [ 10021685, 10021520 ],
    "children" : [ ]
  }, {
    "dbId" : 10018050,
    "stId" : "R-MMU-877348",
    "displayName" : "TYK2 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48892,
    "identifier" : "Q9R117",
    "standardIdentifier" : "uniprot:Q9R117",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Tyk2" ],
    "parents" : [ 10021544 ],
    "children" : [ ]
  }, {
    "dbId" : 10021380,
    "stId" : "R-MMU-877339-6",
    "displayName" : "Ifna4 [extracellular region]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48892,
    "identifier" : "P07351",
    "standardIdentifier" : "uniprot:P07351",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Ifna4" ],
    "parents" : [ 10021410 ],
    "children" : [ ]
  }, {
    "dbId" : 10021432,
    "stId" : "R-MMU-877349-11",
    "displayName" : "Ifna12 [extracellular region]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48892,
    "identifier" : "Q80SS5",
    "standardIdentifier" : "uniprot:Q80SS5",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Ifna12" ],
    "parents" : [ 10021440 ],
    "children" : [ ]
  }, {
    "dbId" : 10018106,
    "stId" : "R-MMU-451898",
    "displayName" : "JAK1 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48892,
    "identifier" : "P52332",
    "standardIdentifier" : "uniprot:P52332",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Jak1" ],
    "parents" : [ 10021496 ],
    "children" : [ ]
  }, {
    "dbId" : 10021434,
    "stId" : "R-MMU-877349-12",
    "displayName" : "Ifna13 [extracellular region]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48892,
    "identifier" : "Q80SU4",
    "standardIdentifier" : "uniprot:Q80SU4",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Ifna13" ],
    "parents" : [ 10021440 ],
    "children" : [ ]
  }, {
    "dbId" : 10021436,
    "stId" : "R-MMU-877349-13",
    "displayName" : "Ifna16 [extracellular region]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48892,
    "identifier" : "Q810G1",
    "standardIdentifier" : "uniprot:Q810G1",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Ifna16" ],
    "parents" : [ 10021440 ],
    "children" : [ ]
  }, {
    "dbId" : 10021438,
    "stId" : "R-MMU-877349-14",
    "displayName" : "Ifna14 [extracellular region]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48892,
    "identifier" : "Q810G3",
    "standardIdentifier" : "uniprot:Q810G3",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Ifna14" ],
    "parents" : [ 10021440 ],
    "children" : [ ]
  }, {
    "dbId" : 10020926,
    "stId" : "R-MMU-380745",
    "displayName" : "Stat1 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48892,
    "diagramIds" : [ 76113, 76069 ],
    "identifier" : "P42225",
    "standardIdentifier" : "uniprot:P42225",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Stat1" ],
    "parents" : [ 10028069 ],
    "children" : [ ]
  }, {
    "dbId" : 10021424,
    "stId" : "R-MMU-877349-7",
    "displayName" : "Ifna4 [extracellular region]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48892,
    "identifier" : "P07351",
    "standardIdentifier" : "uniprot:P07351",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Ifna4" ],
    "parents" : [ 10021440 ],
    "children" : [ ]
  }, {
    "dbId" : 10021426,
    "stId" : "R-MMU-877349-8",
    "displayName" : "Ifna9 [extracellular region]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48892,
    "identifier" : "P09235",
    "standardIdentifier" : "uniprot:P09235",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Ifna9" ],
    "parents" : [ 10021440 ],
    "children" : [ ]
  }, {
    "dbId" : 10021428,
    "stId" : "R-MMU-877349-9",
    "displayName" : "Ifna11 [extracellular region]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48892,
    "identifier" : "Q61716",
    "standardIdentifier" : "uniprot:Q61716",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Ifna11" ],
    "parents" : [ 10021440 ],
    "children" : [ ]
  }, {
    "dbId" : 29356,
    "stId" : "R-ALL-29356",
    "displayName" : "H2O [cytosol]",
    "schemaClass" : "SimpleEntity",
    "speciesId" : 0,
    "diagramIds" : [ 76081, 76086, 76090 ],
    "identifier" : "15377",
    "standardIdentifier" : "chebi:15377",
    "referenceType" : "ReferenceMolecule",
    "parents" : [ ],
    "children" : [ ]
  }, {
    "dbId" : 10021685,
    "stId" : "R-MMU-9757480",
    "displayName" : "p-Y701-STAT1:KPNA1:KPNB1 [cytosol]",
    "schemaClass" : "Complex",
    "speciesId" : 48892,
    "diagramIds" : [ 76074 ],
    "parents" : [ 10090863 ],
    "children" : [ 10020934, 2065541, 9954438 ]
  }, {
    "dbId" : 10021430,
    "stId" : "R-MMU-877349-10",
    "displayName" : "Ifna15 [extracellular region]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48892,
    "identifier" : "Q61718",
    "standardIdentifier" : "uniprot:Q61718",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Ifna15" ],
    "parents" : [ 10021440 ],
    "children" : [ ]
  }, {
    "dbId" : 10021687,
    "stId" : "R-MMU-913526",
    "displayName" : "p-Y701-STAT1 dimer [nucleoplasm]",
    "schemaClass" : "Complex",
    "speciesId" : 48892,
    "diagramIds" : [ 76075 ],
    "parents" : [ ],
    "children" : [ 10021524 ]
  }, {
    "dbId" : 10021416,
    "stId" : "R-MMU-877349-3",
    "displayName" : "Ifna2 [extracellular region]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48892,
    "identifier" : "P01573",
    "standardIdentifier" : "uniprot:P01573",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Ifna2" ],
    "parents" : [ 10021440 ],
    "children" : [ ]
  }, {
    "dbId" : 10028073,
    "stId" : "R-MMU-997304",
    "displayName" : "IFNA/B:IFNAR2:p-JAK1:STAT2:p-IFNAR1:p-TYK2:p-STAT2:STAT1 [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 48892,
    "diagramIds" : [ 76091 ],
    "parents" : [ ],
    "children" : [ 10028071, 10021474, 10021451 ]
  }, {
    "dbId" : 9734438,
    "stId" : "R-ALL-9734438",
    "displayName" : "peginterferon alfa-2a [extracellular region]",
    "schemaClass" : "ProteinDrug",
    "speciesId" : 0,
    "identifier" : "47205819",
    "standardIdentifier" : "pubchem.substance:47205819",
    "parents" : [ 9696187 ],
    "children" : [ ]
  }, {
    "dbId" : 10021418,
    "stId" : "R-MMU-877349-4",
    "displayName" : "Ifna7 [extracellular region]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48892,
    "identifier" : "P06799",
    "standardIdentifier" : "uniprot:P06799",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Ifna7" ],
    "parents" : [ 10021440 ],
    "children" : [ ]
  }, {
    "dbId" : 10021420,
    "stId" : "R-MMU-877349-5",
    "displayName" : "Ifna5 [extracellular region]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48892,
    "identifier" : "P07349",
    "standardIdentifier" : "uniprot:P07349",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Ifna5" ],
    "parents" : [ 10021440 ],
    "children" : [ ]
  }, {
    "dbId" : 9996589,
    "stId" : "R-MMU-162563",
    "displayName" : "PTPN11 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48892,
    "diagramIds" : [ 76093 ],
    "identifier" : "P35235",
    "standardIdentifier" : "uniprot:P35235",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Ptpn11" ],
    "parents" : [ ],
    "children" : [ ]
  }, {
    "dbId" : 10021422,
    "stId" : "R-MMU-877349-6",
    "displayName" : "Ifna6 [extracellular region]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48892,
    "identifier" : "P07350",
    "standardIdentifier" : "uniprot:P07350",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Ifna6" ],
    "parents" : [ 10021440 ],
    "children" : [ ]
  }, {
    "dbId" : 9734435,
    "stId" : "R-ALL-9734435",
    "displayName" : "peginterferon beta-1a [extracellular region]",
    "schemaClass" : "ProteinDrug",
    "speciesId" : 0,
    "identifier" : "7637",
    "standardIdentifier" : "iuphar.ligand:7637",
    "parents" : [ 9696187 ],
    "children" : [ ]
  }, {
    "dbId" : 10028078,
    "stId" : "R-MMU-997300",
    "displayName" : "IFNA/B:IFNAR2:p-JAK1:STAT2:IFNAR1:TYK2 [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 48892,
    "diagramIds" : [ 76083 ],
    "parents" : [ ],
    "children" : [ 10021483, 10021544 ]
  }, {
    "dbId" : 10021408,
    "stId" : "R-MMU-877339-13",
    "displayName" : "Ifna14 [extracellular region]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48892,
    "identifier" : "Q810G3",
    "standardIdentifier" : "uniprot:Q810G3",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Ifna14" ],
    "parents" : [ 10021410 ],
    "children" : [ ]
  }, {
    "dbId" : 113592,
    "stId" : "R-ALL-113592",
    "displayName" : "ATP [cytosol]",
    "schemaClass" : "SimpleEntity",
    "speciesId" : 0,
    "diagramIds" : [ 76054, 76070, 76041, 76046 ],
    "identifier" : "30616",
    "standardIdentifier" : "chebi:30616",
    "referenceType" : "ReferenceMolecule",
    "parents" : [ ],
    "children" : [ ]
  }, {
    "dbId" : 10021410,
    "stId" : "R-MMU-877339-14",
    "displayName" : "Homologues of IFNA10 [extracellular region]",
    "schemaClass" : "DefinedSet",
    "speciesId" : 48892,
    "parents" : [ 10021446 ],
    "children" : [ 10021380, 10021408, 10021376, 10021359, 10021388, 10021384, 10021396, 10021364, 10021392, 912682, 10021404, 10021372, 10021400, 10021368 ]
  }, {
    "dbId" : 29370,
    "stId" : "R-ALL-29370",
    "displayName" : "ADP [cytosol]",
    "schemaClass" : "SimpleEntity",
    "speciesId" : 0,
    "diagramIds" : [ 76048, 76071, 76055, 76043 ],
    "identifier" : "456216",
    "standardIdentifier" : "chebi:456216",
    "referenceType" : "ReferenceMolecule",
    "parents" : [ ],
    "children" : [ ]
  }, {
    "dbId" : 10020898,
    "stId" : "R-MMU-204910",
    "displayName" : "Socs1 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48892,
    "identifier" : "O35716",
    "standardIdentifier" : "uniprot:O35716",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Socs1", "Cish1", "Ssi1" ],
    "parents" : [ 10020900 ],
    "children" : [ ]
  }, {
    "dbId" : 10021412,
    "stId" : "R-MMU-877349",
    "displayName" : "Ifnab [extracellular region]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48892,
    "identifier" : "L7MTU6",
    "standardIdentifier" : "uniprot:L7MTU6",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Ifnab" ],
    "parents" : [ 10021440 ],
    "children" : [ ]
  }, {
    "dbId" : 10020900,
    "stId" : "R-MMU-877267",
    "displayName" : "SOCS-1 and SOCS-3 [cytosol]",
    "schemaClass" : "DefinedSet",
    "speciesId" : 48892,
    "parents" : [ 10021560 ],
    "children" : [ 1169197, 10020898 ]
  }, {
    "dbId" : 10028069,
    "stId" : "R-MMU-997303",
    "displayName" : "p-STAT2:STAT1 [cytosol]",
    "schemaClass" : "Complex",
    "speciesId" : 48892,
    "parents" : [ 10028071 ],
    "children" : [ 10020926, 10021464 ]
  }, {
    "dbId" : 29372,
    "stId" : "R-ALL-29372",
    "displayName" : "Pi [cytosol]",
    "schemaClass" : "SimpleEntity",
    "speciesId" : 0,
    "diagramIds" : [ 76082, 76087, 76092 ],
    "identifier" : "43474",
    "standardIdentifier" : "chebi:43474",
    "referenceType" : "ReferenceMolecule",
    "parents" : [ ],
    "children" : [ ]
  }, {
    "dbId" : 10021414,
    "stId" : "R-MMU-877349-2",
    "displayName" : "Ifna1 [extracellular region]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48892,
    "identifier" : "P01572",
    "standardIdentifier" : "uniprot:P01572",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Ifna1" ],
    "parents" : [ 10021440 ],
    "children" : [ ]
  }, {
    "dbId" : 10028071,
    "stId" : "R-MMU-997302",
    "displayName" : "p-STAT2:STAT1:p-IFNAR1:p-TYK2 [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 48892,
    "parents" : [ 10028073 ],
    "children" : [ 10028069, 10021459, 10021454 ]
  }, {
    "dbId" : 10021464,
    "stId" : "R-MMU-909683",
    "displayName" : "phospho-Stat2 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48892,
    "identifier" : "Q9WVL2",
    "standardIdentifier" : "uniprot:Q9WVL2",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Stat2" ],
    "parents" : [ 10028069, 10021514, 10021466 ],
    "children" : [ ]
  }, {
    "dbId" : 9985370,
    "stId" : "R-MMU-939213",
    "displayName" : "Rps27a [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48892,
    "identifier" : "P62983",
    "standardIdentifier" : "uniprot:P62983",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Rps27a", "Uba80", "Ubcep1" ],
    "parents" : [ 9985374 ],
    "children" : [ ]
  }, {
    "dbId" : 10021466,
    "stId" : "R-MMU-909709",
    "displayName" : "p-STAT2:p-IFNAR1:p-TYK2 [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 48892,
    "parents" : [ 10021476 ],
    "children" : [ 10021459, 10021454, 10021464 ]
  }, {
    "dbId" : 10021470,
    "stId" : "R-MMU-877333",
    "displayName" : "Ifnar2 [plasma membrane]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48892,
    "diagramIds" : [ 76078 ],
    "identifier" : "O35664",
    "standardIdentifier" : "uniprot:O35664",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Ifnar2" ],
    "parents" : [ 10021623, 10021496, 10021474 ],
    "children" : [ ]
  }, {
    "dbId" : 9985374,
    "stId" : "R-MMU-113595",
    "displayName" : "Ub [cytosol]",
    "schemaClass" : "DefinedSet",
    "speciesId" : 48892,
    "parents" : [ 10021491 ],
    "children" : [ 940364, 9985370, 940365, 940362, 940360, 940359, 940388, 940386, 940384, 940382, 940379, 940370, 940371 ]
  }, {
    "dbId" : 10021459,
    "stId" : "R-MMU-909675",
    "displayName" : "phospho-Ifnar1 [plasma membrane]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48892,
    "identifier" : "P33896",
    "standardIdentifier" : "uniprot:P33896",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Ifnar1", "Ifar", "Ifnar" ],
    "parents" : [ 10028071, 10021560, 10021481, 10021487, 10021536, 10021466 ],
    "children" : [ ]
  }, {
    "dbId" : 10019157,
    "stId" : "R-MMU-451921",
    "displayName" : "phospho-p-Y-JAK1 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48892,
    "identifier" : "P52332",
    "standardIdentifier" : "uniprot:P52332",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Jak1" ],
    "parents" : [ 10021474 ],
    "children" : [ ]
  }, {
    "dbId" : 10021449,
    "stId" : "R-MMU-877351",
    "displayName" : "Ifnb1 [extracellular region]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48892,
    "identifier" : "P01575",
    "standardIdentifier" : "uniprot:P01575",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Ifnb1", "Ifb", "Ifnb" ],
    "parents" : [ 10021451 ],
    "children" : [ ]
  }, {
    "dbId" : 10021451,
    "stId" : "R-MMU-909690",
    "displayName" : "IFN alpha/beta (IFNA/B) [extracellular region]",
    "schemaClass" : "DefinedSet",
    "speciesId" : 48892,
    "diagramIds" : [ 76031 ],
    "parents" : [ 10028073, 10021498, 10021483, 10021489, 10021538, 10021476 ],
    "children" : [ 10021446, 10021449 ]
  }, {
    "dbId" : 10021454,
    "stId" : "R-MMU-909682",
    "displayName" : "phospho-p-Y1054,Y1055-TYK2 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48892,
    "identifier" : "Q9R117",
    "standardIdentifier" : "uniprot:Q9R117",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Tyk2" ],
    "parents" : [ 10028071, 10021560, 10021555, 10021481, 10021487, 10021536, 10021466 ],
    "children" : [ ]
  }, {
    "dbId" : 10021440,
    "stId" : "R-MMU-877349-15",
    "displayName" : "Homologues of IFNA2 [extracellular region]",
    "schemaClass" : "DefinedSet",
    "speciesId" : 48892,
    "parents" : [ 10021446 ],
    "children" : [ 10021414, 10021412, 10021422, 10021420, 10021418, 10021416, 10021430, 10021428, 10021426, 10021424, 10021438, 10021436, 10021434, 10021432 ]
  }, {
    "dbId" : 10021442,
    "stId" : "R-MMU-877338",
    "displayName" : "Ifna11 [extracellular region]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48892,
    "identifier" : "Q61716",
    "standardIdentifier" : "uniprot:Q61716",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Ifna11" ],
    "parents" : [ 10021446 ],
    "children" : [ ]
  }, {
    "dbId" : 10020932,
    "stId" : "R-MMU-873791",
    "displayName" : "phospho-Stat1 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48892,
    "identifier" : "P42225",
    "standardIdentifier" : "uniprot:P42225",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Stat1" ],
    "parents" : [ 10021514, 10020934 ],
    "children" : [ ]
  }, {
    "dbId" : 10020934,
    "stId" : "R-MMU-913524",
    "displayName" : "p-Y701-STAT1-1 dimer [cytosol]",
    "schemaClass" : "Complex",
    "speciesId" : 48892,
    "diagramIds" : [ 76072 ],
    "parents" : [ 10090855, 10021685, 10090857 ],
    "children" : [ 10020932 ]
  }, {
    "dbId" : 10021446,
    "stId" : "R-MMU-909688",
    "displayName" : "IFNA [extracellular region]",
    "schemaClass" : "DefinedSet",
    "speciesId" : 48892,
    "parents" : [ 10021451 ],
    "children" : [ 10021442, 10021410, 10021440 ]
  }, {
    "dbId" : 10021496,
    "stId" : "R-MMU-918193",
    "displayName" : "IFNAR2:JAK1:STAT2 [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 48892,
    "diagramIds" : [ 76032 ],
    "parents" : [ 10021502, 10021500, 10021498 ],
    "children" : [ 10021472, 10021470, 10018106 ]
  }, {
    "dbId" : 10009976,
    "stId" : "R-MMU-210625",
    "displayName" : "PTPN1 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48892,
    "diagramIds" : [ 76084 ],
    "identifier" : "P35821",
    "standardIdentifier" : "uniprot:P35821",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Ptpn1" ],
    "parents" : [ ],
    "children" : [ ]
  }, {
    "dbId" : 10021498,
    "stId" : "R-MMU-918195",
    "displayName" : "IFNA/B:IFNAR2:JAK1:STAT2 [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 48892,
    "diagramIds" : [ 76033 ],
    "parents" : [ 10021546 ],
    "children" : [ 10021451, 10021496 ]
  }, {
    "dbId" : 10021500,
    "stId" : "R-MMU-9678951",
    "displayName" : "IFNAR2:JAK1:STAT2:JAK1,2 inhibitors [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 48892,
    "diagramIds" : [ 76035 ],
    "parents" : [ ],
    "children" : [ 9678984, 10021496 ]
  }, {
    "dbId" : 10021502,
    "stId" : "R-MMU-9696161",
    "displayName" : "IFNAR2:JAK1:STAT2:type 1 interferon analogs [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 48892,
    "diagramIds" : [ 76034 ],
    "parents" : [ ],
    "children" : [ 9696187, 10021496 ]
  }, {
    "dbId" : 10021489,
    "stId" : "R-MMU-909696",
    "displayName" : "IFNA/B:IFNAR2:p-JAK1:STAT2:p-IFNAR1:p-TYK2:STAT2 [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 48892,
    "diagramIds" : [ 76051 ],
    "parents" : [ ],
    "children" : [ 10021474, 10021487, 10021451 ]
  }, {
    "dbId" : 10021491,
    "stId" : "R-MMU-9833154",
    "displayName" : "multiubiquitinated STAT2 [cytosol]",
    "schemaClass" : "Complex",
    "speciesId" : 48892,
    "diagramIds" : [ 76052 ],
    "parents" : [ ],
    "children" : [ 10021472, 9985374 ]
  }, {
    "dbId" : 10090857,
    "stId" : "R-MMU-9757485",
    "displayName" : "p-Y701-STAT1:KPNA1 [cytosol]",
    "schemaClass" : "Complex",
    "speciesId" : 48892,
    "parents" : [ 10090859 ],
    "children" : [ 10020934, 9954438 ]
  }, {
    "dbId" : 10021481,
    "stId" : "R-MMU-909694",
    "displayName" : "p-IFNAR1:p-TYK2 [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 48892,
    "parents" : [ 10021485 ],
    "children" : [ 10021459, 10021454 ]
  }, {
    "dbId" : 10090859,
    "stId" : "R-MMU-9757478",
    "displayName" : "p-STAT1 dimer:KPNA1 [cytosol]",
    "schemaClass" : "DefinedSet",
    "speciesId" : 48892,
    "diagramIds" : [ 76107 ],
    "parents" : [ ],
    "children" : [ 10021518, 10090857 ]
  }, {
    "dbId" : 10021483,
    "stId" : "R-MMU-909692",
    "displayName" : "IFNA/B:IFNAR2:p-JAK1:STAT2 [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 48892,
    "parents" : [ 10028078, 10021562, 10021557, 10021485 ],
    "children" : [ 10021474, 10021451 ]
  }, {
    "dbId" : 10021485,
    "stId" : "R-MMU-909704",
    "displayName" : "IFNA/B:IFNAR2:p-JAK1:STAT2:p-IFNAR1:p-TYK2 [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 48892,
    "diagramIds" : [ 76047 ],
    "parents" : [ ],
    "children" : [ 10021483, 10021481 ]
  }, {
    "dbId" : 10090863,
    "stId" : "R-MMU-9757476",
    "displayName" : "p-STAT1 dimer:KPNA1:KPNB1 [cytosol]",
    "schemaClass" : "DefinedSet",
    "speciesId" : 48892,
    "diagramIds" : [ 76110 ],
    "parents" : [ ],
    "children" : [ 10021685, 10021520 ]
  }, {
    "dbId" : 10021487,
    "stId" : "R-MMU-909701",
    "displayName" : "STAT2:p-IFNAR1:p-TYK2 [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 48892,
    "parents" : [ 10021489 ],
    "children" : [ 10021459, 10021472, 10021454 ]
  }, {
    "dbId" : 10021472,
    "stId" : "R-MMU-882029",
    "displayName" : "Stat2 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48892,
    "diagramIds" : [ 76050 ],
    "identifier" : "Q9WVL2",
    "standardIdentifier" : "uniprot:Q9WVL2",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Stat2" ],
    "parents" : [ 10021496, 10021491, 10021487, 10021474 ],
    "children" : [ ]
  }, {
    "dbId" : 10021474,
    "stId" : "R-MMU-909715",
    "displayName" : "IFNAR2:p-JAK1:STAT2 [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 48892,
    "parents" : [ 10028073, 10021483, 10021489, 10021538, 10021476 ],
    "children" : [ 10019157, 10021472, 10021470 ]
  }, {
    "dbId" : 10021476,
    "stId" : "R-MMU-909697",
    "displayName" : "IFNA/B:IFNAR2:p-JAK1:STAT2:p-IFNAR1:p-TYK2:p-STAT2 [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 48892,
    "diagramIds" : [ 76056 ],
    "parents" : [ ],
    "children" : [ 10021474, 10021451, 10021466 ]
  }, {
    "dbId" : 10090855,
    "stId" : "R-MMU-9710957",
    "displayName" : "p-STAT1 dimer, ISGF3 [cytosol]",
    "schemaClass" : "DefinedSet",
    "speciesId" : 48892,
    "diagramIds" : [ 76106 ],
    "parents" : [ ],
    "children" : [ 10020934, 10021516 ]
  } ],
  "edges" : [ {
    "dbId" : 10021689,
    "stId" : "R-MMU-913529",
    "displayName" : "Translocation of p-STAT1:p-STAT1 dimer to nucleus",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "preceding" : [ 10090865 ],
    "inputs" : [ 10021685 ],
    "outputs" : [ 10021687, 10006705, 10006703 ],
    "efs" : [ ],
    "diagramIds" : [ 76073 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10053080,
    "stId" : "R-MMU-5223305",
    "displayName" : "ABCE1 binds RNASEL, inhibiting it",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "inputs" : [ 10053076, 10053072 ],
    "outputs" : [ 10053078 ],
    "efs" : [ ],
    "diagramIds" : [ 76094 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10021625,
    "stId" : "R-MMU-912685",
    "displayName" : "UBP43 binds IFNAR2 and prevents JAK1 interaction",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "inputs" : [ 10021621, 10021470 ],
    "outputs" : [ 10021623 ],
    "efs" : [ ],
    "diagramIds" : [ 76076 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10090138,
    "stId" : "R-MMU-9696179",
    "displayName" : "IFNAR2:JAK1:STAT2 binds type 1 interferon analogs",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "inputs" : [ 9696187, 10021496 ],
    "outputs" : [ 10021502 ],
    "efs" : [ ],
    "diagramIds" : [ 76102 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10021564,
    "stId" : "R-MMU-909729",
    "displayName" : "Activation of JAK kinases",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "preceding" : [ 10021550 ],
    "following" : [ 10028080, 10021568 ],
    "inputs" : [ 113592, 10021546 ],
    "outputs" : [ 10021557, 29370 ],
    "catalysts" : [ 10021546 ],
    "efs" : [ ],
    "inhibitors" : [ 10021562 ],
    "diagramIds" : [ 76040 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10021534,
    "stId" : "R-MMU-909721",
    "displayName" : "Translocation of ISGF3 complex to nucleus",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "preceding" : [ 10090865 ],
    "inputs" : [ 10021520 ],
    "outputs" : [ 10006705, 10006703, 10021532 ],
    "efs" : [ ],
    "diagramIds" : [ 76063 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10090865,
    "stId" : "R-MMU-9710963",
    "displayName" : "p-STAT1dimer:KPNA1 binds KPNB1",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "preceding" : [ 10090861 ],
    "following" : [ 10021689, 10021534 ],
    "inputs" : [ 2065541, 10090859 ],
    "outputs" : [ 10090863 ],
    "efs" : [ ],
    "diagramIds" : [ 76108 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10021553,
    "stId" : "R-MMU-909725",
    "displayName" : "Interaction of IRF9 with p-STAT2:p-STAT1",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "preceding" : [ 10021540 ],
    "following" : [ 10090861 ],
    "inputs" : [ 10021510, 10021514 ],
    "outputs" : [ 10021516 ],
    "efs" : [ ],
    "diagramIds" : [ 76060 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10028080,
    "stId" : "R-MMU-997311",
    "displayName" : "Dephosphorylation of TYK2 by PTP1B",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "preceding" : [ 10021564 ],
    "following" : [ 10028083 ],
    "inputs" : [ 10021557, 29356 ],
    "outputs" : [ 29372, 10028078 ],
    "catalysts" : [ 10009976 ],
    "efs" : [ ],
    "diagramIds" : [ 76080 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10028083,
    "stId" : "R-MMU-997314",
    "displayName" : "Dephosphorylation of JAK1 by SHP1",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "preceding" : [ 10028080 ],
    "inputs" : [ 29356, 10028078 ],
    "outputs" : [ 29372, 10021546 ],
    "catalysts" : [ 10006039 ],
    "efs" : [ ],
    "diagramIds" : [ 76085 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10021493,
    "stId" : "R-MMU-909719",
    "displayName" : "Recruitment of STAT2 to p-IFNAR1",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "preceding" : [ 10021568 ],
    "following" : [ 10021571 ],
    "inputs" : [ 10021472, 10021485 ],
    "outputs" : [ 10021489 ],
    "efs" : [ ],
    "inhibitors" : [ 10021491 ],
    "diagramIds" : [ 76049 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10089751,
    "stId" : "R-MMU-9678737",
    "displayName" : "IFNAR1:TYK2 binds TYK2 inhibitors",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "inputs" : [ 9678619, 10021544 ],
    "outputs" : [ 10021548 ],
    "efs" : [ ],
    "diagramIds" : [ 76100 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10090861,
    "stId" : "R-MMU-9710959",
    "displayName" : "p-STAT1 dimer binds KPNA1",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "preceding" : [ 10021479, 10021553 ],
    "following" : [ 10090865 ],
    "inputs" : [ 10090855, 9954438 ],
    "outputs" : [ 10090859 ],
    "efs" : [ ],
    "diagramIds" : [ 76104 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10028076,
    "stId" : "R-MMU-997309",
    "displayName" : "Dephosphorylation of STAT1 by SHP2",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "inputs" : [ 29356, 10021538 ],
    "outputs" : [ 29372, 10028073 ],
    "catalysts" : [ 9996589 ],
    "efs" : [ ],
    "diagramIds" : [ 76089 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10089775,
    "stId" : "R-MMU-9678935",
    "displayName" : "IFNAR2:JAK1:STAT2 binds JAK1,2 inhibitors",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "inputs" : [ 9678984, 10021496 ],
    "outputs" : [ 10021500 ],
    "efs" : [ ],
    "diagramIds" : [ 76098 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10021550,
    "stId" : "R-MMU-909724",
    "displayName" : "Recruitment of IFNAR1",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "preceding" : [ 10021504 ],
    "following" : [ 10021564 ],
    "inputs" : [ 10021498, 10021544 ],
    "outputs" : [ 10021546 ],
    "efs" : [ ],
    "inhibitors" : [ 10021548 ],
    "diagramIds" : [ 76036 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10021504,
    "stId" : "R-MMU-909720",
    "displayName" : "IFN alpha/beta binds to IFNAR2",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "following" : [ 10021550 ],
    "inputs" : [ 10021451, 10021496 ],
    "outputs" : [ 10021498 ],
    "efs" : [ ],
    "inhibitors" : [ 10021500 ],
    "activators" : [ 10021502 ],
    "diagramIds" : [ 76030 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10021568,
    "stId" : "R-MMU-909730",
    "displayName" : "Phosphorylation of INFAR1 by TYK2",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "preceding" : [ 10021564 ],
    "following" : [ 10021493 ],
    "inputs" : [ 10021557, 113592 ],
    "outputs" : [ 29370, 10021485 ],
    "catalysts" : [ 10021557 ],
    "efs" : [ ],
    "diagramIds" : [ 76045 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10021571,
    "stId" : "R-MMU-909732",
    "displayName" : "Phosphorylation of STAT2",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "preceding" : [ 10021493 ],
    "following" : [ 10021479 ],
    "inputs" : [ 10021489, 113592 ],
    "outputs" : [ 10021476, 29370 ],
    "catalysts" : [ 10021489 ],
    "efs" : [ ],
    "diagramIds" : [ 76053 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10021540,
    "stId" : "R-MMU-909722",
    "displayName" : "Release of p-STAT2:p-STAT1 dimer",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "following" : [ 10021553 ],
    "inputs" : [ 10021538 ],
    "outputs" : [ 10021485, 10021514 ],
    "efs" : [ ],
    "diagramIds" : [ 76057 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10021479,
    "stId" : "R-MMU-909718",
    "displayName" : "Formation of p-STAT1 homodimer",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "preceding" : [ 10021571 ],
    "following" : [ 10090861 ],
    "inputs" : [ 113592, 10020926 ],
    "outputs" : [ 10020934, 29370 ],
    "catalysts" : [ 10021476 ],
    "efs" : [ ],
    "diagramIds" : [ 76068 ],
    "entityFunctionalStatus" : [ ]
  } ],
  "subpathways" : [ {
    "dbId" : 10100491,
    "stId" : "R-MMU-912694",
    "displayName" : "Regulation of IFNA/IFNB signaling",
    "events" : [ 10021625, 10028076, 10028080, 10028083 ]
  } ]
}