{
  "dbId" : 10100375,
  "stId" : "R-MMU-451927",
  "speciesName" : "Mus musculus",
  "nodes" : [ {
    "dbId" : 10019227,
    "stId" : "R-MMU-912312",
    "displayName" : "phospho-Csf2rb [plasma membrane]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48892,
    "identifier" : "P26955",
    "standardIdentifier" : "uniprot:P26955",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Csf2rb" ],
    "parents" : [ 10019277, 10019229 ],
    "children" : [ ]
  }, {
    "dbId" : 10019229,
    "stId" : "R-MMU-912316",
    "displayName" : "pY593,Y628-IL3RB:JAK2 [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 48892,
    "parents" : [ 10019263, 10019247, 10019231 ],
    "children" : [ 10018060, 10019227 ]
  }, {
    "dbId" : 10019231,
    "stId" : "R-MMU-912308",
    "displayName" : "IL3:IL3RA:p-Y593,Y628-IL3RB:JAK2 [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 48892,
    "parents" : [ 10019233 ],
    "children" : [ 10019221, 10019229 ]
  }, {
    "dbId" : 9027214,
    "stId" : "R-MMU-9027214",
    "displayName" : "Pik3ca [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48892,
    "identifier" : "P42337",
    "standardIdentifier" : "uniprot:P42337",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Pik3ca" ],
    "parents" : [ 9992956 ],
    "children" : [ ]
  }, {
    "dbId" : 10019219,
    "stId" : "R-MMU-879938",
    "displayName" : "Ghost homologue of IL3RA [plasma membrane]",
    "schemaClass" : "GenomeEncodedEntity",
    "speciesId" : 48892,
    "parents" : [ 10019221 ],
    "children" : [ ]
  }, {
    "dbId" : 10019221,
    "stId" : "R-MMU-450048",
    "displayName" : "IL3:IL3RA [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 48892,
    "parents" : [ 10019279, 10019231 ],
    "children" : [ 10019219, 10018589 ]
  }, {
    "dbId" : 10100373,
    "stId" : "R-MMU-8983432",
    "displayName" : "Interleukin-15 signaling",
    "schemaClass" : "Pathway",
    "speciesId" : 48892,
    "diagramIds" : [ 119774 ]
  }, {
    "dbId" : 10018440,
    "stId" : "R-MMU-451893",
    "displayName" : "JAK3 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48892,
    "diagramIds" : [ 119681 ],
    "identifier" : "Q62137",
    "standardIdentifier" : "uniprot:Q62137",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Jak3" ],
    "parents" : [ 10020174, 10020169, 10019150, 10018442 ],
    "children" : [ ]
  }, {
    "dbId" : 10019209,
    "stId" : "R-MMU-453105",
    "displayName" : "SHC kinases in IL2 signaling [cytosol]",
    "schemaClass" : "CandidateSet",
    "speciesId" : 48892,
    "diagramIds" : [ 119711 ],
    "parents" : [ ],
    "children" : [ 10004341, 10019157 ]
  }, {
    "dbId" : 10018442,
    "stId" : "R-MMU-451911",
    "displayName" : "IL2RG:JAK3 [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 48892,
    "diagramIds" : [ 119683 ],
    "parents" : [ 10085325, 10018583, 10019165, 10019184 ],
    "children" : [ 539020, 10018440 ]
  }, {
    "dbId" : 10013324,
    "stId" : "R-MMU-390932",
    "displayName" : "PTK2B [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48892,
    "diagramIds" : [ 119747 ],
    "identifier" : "Q9QVP9",
    "standardIdentifier" : "uniprot:Q9QVP9",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 10020169 ],
    "children" : [ ]
  }, {
    "dbId" : 10012032,
    "stId" : "R-MMU-380737",
    "displayName" : "Stat5b [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48892,
    "identifier" : "P42232",
    "standardIdentifier" : "uniprot:P42232",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Stat5b" ],
    "parents" : [ 10084810, 10019190 ],
    "children" : [ ]
  }, {
    "dbId" : 10019200,
    "stId" : "R-MMU-507943",
    "displayName" : "IL2:IL2R trimer p-(Y338,Y392, Y510) beta subunit:p-JAK1:JAK3:p-STAT5 [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 48892,
    "diagramIds" : [ 119736 ],
    "parents" : [ ],
    "children" : [ 10019184, 10019198 ]
  }, {
    "dbId" : 10018434,
    "stId" : "R-MMU-197876",
    "displayName" : "Il2rb [plasma membrane]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48892,
    "diagramIds" : [ 119678 ],
    "identifier" : "P16297",
    "standardIdentifier" : "uniprot:P16297",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Il2rb" ],
    "parents" : [ 10018436, 10019159 ],
    "children" : [ ]
  }, {
    "dbId" : 9989250,
    "stId" : "R-MMU-74680",
    "displayName" : "Shc1 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48892,
    "diagramIds" : [ 119702 ],
    "identifier" : "P98083",
    "standardIdentifier" : "uniprot:P98083",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Shc1", "Shc", "ShcA" ],
    "parents" : [ 10019186 ],
    "children" : [ ]
  }, {
    "dbId" : 10012035,
    "stId" : "R-MMU-629622",
    "displayName" : "Stat1 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48892,
    "identifier" : "P42225",
    "standardIdentifier" : "uniprot:P42225",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Stat1" ],
    "parents" : [ 10085339 ],
    "children" : [ ]
  }, {
    "dbId" : 10018436,
    "stId" : "R-MMU-451905",
    "displayName" : "IL2RB:JAK1 [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 48892,
    "diagramIds" : [ 119679 ],
    "parents" : [ 10018577 ],
    "children" : [ 10018434, 10018106 ]
  }, {
    "dbId" : 10019205,
    "stId" : "R-MMU-162568",
    "displayName" : "phospho-Shc1 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48892,
    "identifier" : "P98083",
    "standardIdentifier" : "uniprot:P98083",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Shc1", "Shc", "ShcA" ],
    "parents" : [ 10019207 ],
    "children" : [ ]
  }, {
    "dbId" : 10019207,
    "stId" : "R-MMU-453099",
    "displayName" : "IL2:IL2R trimer p-(Y338,392,510)-beta subunit:p-JAK1:JAK3:p-SHC [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 48892,
    "diagramIds" : [ 119710 ],
    "parents" : [ 10019275, 10020130, 10019271 ],
    "children" : [ 10019205, 10019184 ]
  }, {
    "dbId" : 10019257,
    "stId" : "R-MMU-447159",
    "displayName" : "Il5 [extracellular region]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48892,
    "identifier" : "P04401",
    "standardIdentifier" : "uniprot:P04401",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Il5", "Il-5" ],
    "parents" : [ 10019259 ],
    "children" : [ ]
  }, {
    "dbId" : 10019259,
    "stId" : "R-MMU-913383",
    "displayName" : "IL5 homodimer [extracellular region]",
    "schemaClass" : "Complex",
    "speciesId" : 48892,
    "parents" : [ 10019261 ],
    "children" : [ 10019257 ]
  }, {
    "dbId" : 10100415,
    "stId" : "R-MMU-8985947",
    "displayName" : "Interleukin-9 signaling",
    "schemaClass" : "Pathway",
    "speciesId" : 48892,
    "diagramIds" : [ 119773 ]
  }, {
    "dbId" : 10019261,
    "stId" : "R-MMU-450056",
    "displayName" : "IL5 homodimer:IL5RA [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 48892,
    "parents" : [ 10019263 ],
    "children" : [ 10019255, 10019259 ]
  }, {
    "dbId" : 9678772,
    "stId" : "R-ALL-9678772",
    "displayName" : "JAK3 inhibitors [cytosol]",
    "schemaClass" : "DefinedSet",
    "speciesId" : 0,
    "diagramIds" : [ 119769 ],
    "parents" : [ 10019150 ],
    "children" : [ 9678829, 9678779, 9678901, 9678960, 9678786 ]
  }, {
    "dbId" : 10019263,
    "stId" : "R-MMU-913357",
    "displayName" : "IL5 homodimer:IL5RA:p(Y593, 628)-Bc:JAK2 [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 48892,
    "parents" : [ 10019265 ],
    "children" : [ 10019229, 10019261 ]
  }, {
    "dbId" : 10082481,
    "stId" : "R-MMU-8950343",
    "displayName" : "phospho-Stat4 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48892,
    "identifier" : "P42228",
    "standardIdentifier" : "uniprot:P42228",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Stat4" ],
    "parents" : [ 10085345 ],
    "children" : [ ]
  }, {
    "dbId" : 9678779,
    "stId" : "R-ALL-9678779",
    "displayName" : "tofacitinib [cytosol]",
    "schemaClass" : "ChemicalDrug",
    "speciesId" : 0,
    "identifier" : "5677",
    "standardIdentifier" : "iuphar.ligand:5677",
    "chebiIdentifier" : "chebi:71200",
    "parents" : [ 9678772 ],
    "children" : [ ]
  }, {
    "dbId" : 10004400,
    "stId" : "R-MMU-197940",
    "displayName" : "Inpp5d [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48892,
    "identifier" : "Q9ES52",
    "standardIdentifier" : "uniprot:Q9ES52",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Inpp5d", "7a33", "Ship", "Ship1" ],
    "parents" : [ 10021667 ],
    "children" : [ ]
  }, {
    "dbId" : 10019249,
    "stId" : "R-MMU-913384",
    "displayName" : "High affinity GM-CSF receptor complex dimer, inactive JAK2, p(Y593, 628)- Bc [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 48892,
    "parents" : [ 10019251 ],
    "children" : [ 10019247 ]
  }, {
    "dbId" : 10085299,
    "stId" : "R-MMU-9005970",
    "displayName" : "Il21r [plasma membrane]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48892,
    "identifier" : "Q9JHX3",
    "standardIdentifier" : "uniprot:Q9JHX3",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Il21r" ],
    "parents" : [ 10085301, 10085331 ],
    "children" : [ ]
  }, {
    "dbId" : 10019251,
    "stId" : "R-MMU-913428",
    "displayName" : "High affinity GM-CSF receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 48892,
    "parents" : [ 10019289, 10020134, 10019269 ],
    "children" : [ 10019235, 10019249 ]
  }, {
    "dbId" : 10085301,
    "stId" : "R-MMU-9006858",
    "displayName" : "IL21R:JAK1 [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 48892,
    "diagramIds" : [ 119753 ],
    "parents" : [ 10085303 ],
    "children" : [ 10085299, 10018106 ]
  }, {
    "dbId" : 10085303,
    "stId" : "R-MMU-9005977",
    "displayName" : "IL21:IL21R:JAK1 [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 48892,
    "diagramIds" : [ 119754 ],
    "parents" : [ 10085325 ],
    "children" : [ 10085301, 10085295 ]
  }, {
    "dbId" : 10019255,
    "stId" : "R-MMU-450072",
    "displayName" : "Il5ra [plasma membrane]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48892,
    "identifier" : "P21183",
    "standardIdentifier" : "uniprot:P21183",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Il5ra" ],
    "parents" : [ 10019261 ],
    "children" : [ ]
  }, {
    "dbId" : 10019243,
    "stId" : "R-MMU-517562",
    "displayName" : "Csf2 [extracellular region]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48892,
    "identifier" : "P01587",
    "standardIdentifier" : "uniprot:P01587",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Csf2" ],
    "parents" : [ 10019245 ],
    "children" : [ ]
  }, {
    "dbId" : 10019245,
    "stId" : "R-MMU-913362",
    "displayName" : "GM-CSF:GM-CSF receptor alpha subunit [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 48892,
    "parents" : [ 10019247 ],
    "children" : [ 10019239, 10019243 ]
  }, {
    "dbId" : 10085295,
    "stId" : "R-MMU-448458",
    "displayName" : "Il21 [extracellular region]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48892,
    "diagramIds" : [ 119752 ],
    "identifier" : "Q9ES17",
    "standardIdentifier" : "uniprot:Q9ES17",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Il21" ],
    "parents" : [ 10085303, 10085333 ],
    "children" : [ ]
  }, {
    "dbId" : 10019247,
    "stId" : "R-MMU-913355",
    "displayName" : "GM-CSF:GM-CSF receptor alpha subunit:p(Y593, 628)-Bc:JAK2 [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 48892,
    "parents" : [ 10019249 ],
    "children" : [ 10019229, 10019245 ]
  }, {
    "dbId" : 10019233,
    "stId" : "R-MMU-912317",
    "displayName" : "IL3:IL3R active complex, JAK2:p-Y593,Y629-IL3RB [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 48892,
    "parents" : [ 10019283, 10019237 ],
    "children" : [ 10019231 ]
  }, {
    "dbId" : 10019235,
    "stId" : "R-MMU-912321",
    "displayName" : "phospho-Shc1 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48892,
    "identifier" : "P98083",
    "standardIdentifier" : "uniprot:P98083",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Shc1", "Shc", "ShcA" ],
    "parents" : [ 10019285, 10019267, 10019251, 10019237 ],
    "children" : [ ]
  }, {
    "dbId" : 10019237,
    "stId" : "R-MMU-913412",
    "displayName" : "IL3:IL3R active complex, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 48892,
    "parents" : [ 10019269 ],
    "children" : [ 10019235, 10019233 ]
  }, {
    "dbId" : 10019239,
    "stId" : "R-MMU-913361",
    "displayName" : "Ghost homologue of CSF2RA [plasma membrane]",
    "schemaClass" : "GenomeEncodedEntity",
    "speciesId" : 48892,
    "parents" : [ 10019245 ],
    "children" : [ ]
  }, {
    "dbId" : 10019289,
    "stId" : "R-MMU-914021",
    "displayName" : "High affinity GM-CSF receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1:GRB2:GAB2 [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 48892,
    "parents" : [ 10019293 ],
    "children" : [ 10019251, 10019273 ]
  }, {
    "dbId" : 10085339,
    "stId" : "R-MMU-9006868",
    "displayName" : "STAT1,STAT3,STAT4,STAT5 [cytosol]",
    "schemaClass" : "DefinedSet",
    "speciesId" : 48892,
    "diagramIds" : [ 119762 ],
    "parents" : [ 10085341 ],
    "children" : [ 10082500, 10012035, 10084810, 10012026 ]
  }, {
    "dbId" : 10019291,
    "stId" : "R-MMU-914047",
    "displayName" : "High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1:GRB2:GAB2 [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 48892,
    "parents" : [ 10019293 ],
    "children" : [ 10019267, 10019273 ]
  }, {
    "dbId" : 10085341,
    "stId" : "R-MMU-9006875",
    "displayName" : "IL21:IL21R:p-Y-JAK1:IL2RG:p-Y-JAK3:STAT1,STAT3,STAT4,STAT5 [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 48892,
    "diagramIds" : [ 119763 ],
    "parents" : [ ],
    "children" : [ 10085335, 10085339 ]
  }, {
    "dbId" : 10019293,
    "stId" : "R-MMU-914052",
    "displayName" : "High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(Y593,628)- Bc:p(427,349,350)-SHC1:GRB2:GAB2 [plasma membrane]",
    "schemaClass" : "DefinedSet",
    "speciesId" : 48892,
    "parents" : [ 10019295 ],
    "children" : [ 10019287, 10019291, 10019289 ]
  }, {
    "dbId" : 10085343,
    "stId" : "R-MMU-1295524",
    "displayName" : "(p-Y694-STAT5A,p-Y699-STAT5B) [cytosol]",
    "schemaClass" : "CandidateSet",
    "speciesId" : 48892,
    "parents" : [ 10085345 ],
    "children" : [ 10019196, 10019194 ]
  }, {
    "dbId" : 9991646,
    "stId" : "R-MMU-873799",
    "displayName" : "phospho-p-Y1007-JAK2 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48892,
    "identifier" : "Q62120",
    "standardIdentifier" : "uniprot:Q62120",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Jak2" ],
    "parents" : [ 10019277 ],
    "children" : [ ]
  }, {
    "dbId" : 10019295,
    "stId" : "R-MMU-912537",
    "displayName" : "Interleukin receptor compexes with activated Shc:GRB2:GAB2 [plasma membrane]",
    "schemaClass" : "DefinedSet",
    "speciesId" : 48892,
    "diagramIds" : [ 119715 ],
    "parents" : [ ],
    "children" : [ 10019293, 10019275 ]
  }, {
    "dbId" : 10085329,
    "stId" : "R-MMU-9006853",
    "displayName" : "IL2RG:p-Y-JAK3 [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 48892,
    "parents" : [ 10085335 ],
    "children" : [ 10084820, 539020 ]
  }, {
    "dbId" : 10019281,
    "stId" : "R-MMU-912314",
    "displayName" : "IL3:IL3R active complex, activated JAK2, phosphorylated Bc [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 48892,
    "parents" : [ 10019283 ],
    "children" : [ 10019279 ]
  }, {
    "dbId" : 10085331,
    "stId" : "R-MMU-9006860",
    "displayName" : "IL21R:p-Y-JAK1 [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 48892,
    "parents" : [ 10085333 ],
    "children" : [ 10019157, 10085299 ]
  }, {
    "dbId" : 10019283,
    "stId" : "R-MMU-912320",
    "displayName" : "IL3:IL3R active complex, phosphorylated Bc [plasma membrane]",
    "schemaClass" : "DefinedSet",
    "speciesId" : 48892,
    "parents" : [ 10019285 ],
    "children" : [ 10019233, 10019281 ]
  }, {
    "dbId" : 10085333,
    "stId" : "R-MMU-9006855",
    "displayName" : "IL21:IL21R:p-Y-JAK1 [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 48892,
    "parents" : [ 10085335 ],
    "children" : [ 10085331, 10085295 ]
  }, {
    "dbId" : 10084820,
    "stId" : "R-MMU-9006854",
    "displayName" : "phospho-p-Y-JAK3 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48892,
    "identifier" : "Q62137",
    "standardIdentifier" : "uniprot:Q62137",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Jak3" ],
    "parents" : [ 10085329 ],
    "children" : [ ]
  }, {
    "dbId" : 10019285,
    "stId" : "R-MMU-912313",
    "displayName" : "IL3:IL3R active complex, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 48892,
    "parents" : [ 10019287, 10020132 ],
    "children" : [ 10019235, 10019283 ]
  }, {
    "dbId" : 10085335,
    "stId" : "R-MMU-9006856",
    "displayName" : "IL21:IL21R:p-Y-JAK1:IL2RG:p-Y-JAK3 [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 48892,
    "diagramIds" : [ 119760 ],
    "parents" : [ 10085347, 10085341 ],
    "children" : [ 10085333, 10085329 ]
  }, {
    "dbId" : 10019287,
    "stId" : "R-MMU-912538",
    "displayName" : "IL3:IL3R active complex, phosphorylated Bc:p(Y427,349,350)-SHC1:GRB2:GAB2 [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 48892,
    "parents" : [ 10019293 ],
    "children" : [ 10019285, 10019273 ]
  }, {
    "dbId" : 9678786,
    "stId" : "R-ALL-9678786",
    "displayName" : "ruxolitinib [cytosol]",
    "schemaClass" : "ChemicalDrug",
    "speciesId" : 0,
    "identifier" : "5688",
    "standardIdentifier" : "iuphar.ligand:5688",
    "chebiIdentifier" : "chebi:66919",
    "parents" : [ 9678772 ],
    "children" : [ ]
  }, {
    "dbId" : 10019273,
    "stId" : "R-MMU-912522",
    "displayName" : "GRB2:GAB2 [cytosol]",
    "schemaClass" : "Complex",
    "speciesId" : 48892,
    "diagramIds" : [ 119714 ],
    "parents" : [ 10019289, 10019287, 10019291, 10019275 ],
    "children" : [ 9989218, 10005986 ]
  }, {
    "dbId" : 10084810,
    "stId" : "R-MMU-1295523",
    "displayName" : "STAT5 [cytosol]",
    "schemaClass" : "CandidateSet",
    "speciesId" : 48892,
    "parents" : [ 10085339 ],
    "children" : [ 10012032, 10012029 ]
  }, {
    "dbId" : 10019275,
    "stId" : "R-MMU-508246",
    "displayName" : "IL2:IL2R trimer p(Y338,392,510) beta subunit:p-SHC:GRB2:GAB2 [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 48892,
    "parents" : [ 10019295 ],
    "children" : [ 10019207, 10019273 ]
  }, {
    "dbId" : 10085325,
    "stId" : "R-MMU-9006846",
    "displayName" : "IL21:IL21R:JAK1:IL2RG:JAK3 [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 48892,
    "diagramIds" : [ 119756 ],
    "parents" : [ ],
    "children" : [ 10085303, 10018442 ]
  }, {
    "dbId" : 10019277,
    "stId" : "R-MMU-912306",
    "displayName" : "p(Y593)-IL3RB:Activated JAK2 [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 48892,
    "parents" : [ 10019279 ],
    "children" : [ 9991646, 10019227 ]
  }, {
    "dbId" : 10019279,
    "stId" : "R-MMU-912319",
    "displayName" : "IL3RA:IL3:p(Y593)-IL3RB:Activated JAK2 [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 48892,
    "parents" : [ 10019281 ],
    "children" : [ 10019221, 10019277 ]
  }, {
    "dbId" : 10019265,
    "stId" : "R-MMU-913359",
    "displayName" : "High affinity IL-5 receptor complex dimer, inactive JAK2, p(Y593, 628)-Bc [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 48892,
    "parents" : [ 10019267 ],
    "children" : [ 10019263 ]
  }, {
    "dbId" : 10019267,
    "stId" : "R-MMU-913366",
    "displayName" : "High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 48892,
    "parents" : [ 10019291, 10020136, 10019269 ],
    "children" : [ 10019235, 10019265 ]
  }, {
    "dbId" : 10082500,
    "stId" : "R-MMU-8950606",
    "displayName" : "Stat4 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48892,
    "identifier" : "P42228",
    "standardIdentifier" : "uniprot:P42228",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Stat4" ],
    "parents" : [ 10085339 ],
    "children" : [ ]
  }, {
    "dbId" : 10019269,
    "stId" : "R-MMU-913439",
    "displayName" : "High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p-(Y593,628)-Bc:p(427,349,350)-SHC1 [plasma membrane]",
    "schemaClass" : "DefinedSet",
    "speciesId" : 48892,
    "parents" : [ 10019271 ],
    "children" : [ 10019237, 10019267, 10019251 ]
  }, {
    "dbId" : 10019271,
    "stId" : "R-MMU-912534",
    "displayName" : "Interleukin receptor complexes with activated SHC1 [plasma membrane]",
    "schemaClass" : "DefinedSet",
    "speciesId" : 48892,
    "diagramIds" : [ 119713 ],
    "parents" : [ 10021673, 10021669, 10019299 ],
    "children" : [ 10019207, 10019269 ]
  }, {
    "dbId" : 9992952,
    "stId" : "R-MMU-205223",
    "displayName" : "Pik3r3 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48892,
    "identifier" : "Q64143",
    "standardIdentifier" : "uniprot:Q64143",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Pik3r3" ],
    "parents" : [ 9992954 ],
    "children" : [ ]
  }, {
    "dbId" : 9992954,
    "stId" : "R-MMU-391342",
    "displayName" : "PI3K-regulatory subunits [cytosol]",
    "schemaClass" : "CandidateSet",
    "speciesId" : 48892,
    "parents" : [ 10012672, 10012674, 9992956 ],
    "children" : [ 9989230, 9989233, 9992952 ]
  }, {
    "dbId" : 9992956,
    "stId" : "R-MMU-198379",
    "displayName" : "PI3K alpha [cytosol]",
    "schemaClass" : "Complex",
    "speciesId" : 48892,
    "parents" : [ 10020126 ],
    "children" : [ 9027214, 9992954 ]
  }, {
    "dbId" : 10012670,
    "stId" : "R-MMU-392274",
    "displayName" : "Pik3cd [plasma membrane]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48892,
    "identifier" : "O35904",
    "standardIdentifier" : "uniprot:O35904",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Pik3cd" ],
    "parents" : [ 10012672 ],
    "children" : [ ]
  }, {
    "dbId" : 10085345,
    "stId" : "R-MMU-9006876",
    "displayName" : "p-Y701-STAT1, p-Y705-STAT3,p-Y693-STAT4,(p-Y694-STAT5A,p-Y699-STAT5B) [cytosol]",
    "schemaClass" : "DefinedSet",
    "speciesId" : 48892,
    "parents" : [ 10085347 ],
    "children" : [ 10020932, 10028352, 10082481, 10085343 ]
  }, {
    "dbId" : 10085347,
    "stId" : "R-MMU-9006869",
    "displayName" : "IL21:IL21R:p-Y-JAK1:IL2RG:p-Y-JAK3:p-Y701-STAT1,p-Y705-STAT3,p-Y693-STAT4,(p-Y694-STAT5A,p-Y699-STAT5B) [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 48892,
    "diagramIds" : [ 119766 ],
    "parents" : [ ],
    "children" : [ 10085335, 10085345 ]
  }, {
    "dbId" : 10005986,
    "stId" : "R-MMU-508239",
    "displayName" : "Gab2 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48892,
    "identifier" : "Q9Z1S8",
    "standardIdentifier" : "uniprot:Q9Z1S8",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Gab2" ],
    "parents" : [ 10019273 ],
    "children" : [ ]
  }, {
    "dbId" : 10019299,
    "stId" : "R-MMU-921157",
    "displayName" : "Interleukin receptor complexes with activated SHC1:GRB2:SOS1 [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 48892,
    "diagramIds" : [ 119725 ],
    "parents" : [ ],
    "children" : [ 9989223, 10019271 ]
  }, {
    "dbId" : 9678829,
    "stId" : "R-ALL-9678829",
    "displayName" : "baricitinib [cytosol]",
    "schemaClass" : "ChemicalDrug",
    "speciesId" : 0,
    "identifier" : "7792",
    "standardIdentifier" : "iuphar.ligand:7792",
    "chebiIdentifier" : "chebi:95341",
    "parents" : [ 9678772 ],
    "children" : [ ]
  }, {
    "dbId" : 539020,
    "stId" : "R-MMU-539020",
    "displayName" : "Il2rg [plasma membrane]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48892,
    "diagramIds" : [ 119682 ],
    "identifier" : "P34902",
    "standardIdentifier" : "uniprot:P34902",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Il2rg" ],
    "parents" : [ 10085329, 10018442 ],
    "children" : [ ]
  }, {
    "dbId" : 10018589,
    "stId" : "R-MMU-450059",
    "displayName" : "Il3 [extracellular region]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48892,
    "identifier" : "P01586",
    "standardIdentifier" : "uniprot:P01586",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Il3" ],
    "parents" : [ 10019221 ],
    "children" : [ ]
  }, {
    "dbId" : 10020126,
    "stId" : "R-MMU-508248",
    "displayName" : "p85-containing Class 1A PI3Ks [cytosol]",
    "schemaClass" : "DefinedSet",
    "speciesId" : 48892,
    "diagramIds" : [ 119721 ],
    "parents" : [ 10020142, 10020146, 10020144, 10020148 ],
    "children" : [ 10012674, 10012672, 9992956 ]
  }, {
    "dbId" : 10018577,
    "stId" : "R-MMU-450065",
    "displayName" : "IL2:IL2RA:IL2RB:JAK1 [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 48892,
    "diagramIds" : [ 119690 ],
    "parents" : [ 10018583 ],
    "children" : [ 10018436, 10018575 ]
  }, {
    "dbId" : 10018583,
    "stId" : "R-MMU-450080",
    "displayName" : "IL2:IL2R trimer:JAK1:JAK3 [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 48892,
    "diagramIds" : [ 119692 ],
    "parents" : [ ],
    "children" : [ 10018577, 10018442 ]
  }, {
    "dbId" : 10006039,
    "stId" : "R-MMU-197938",
    "displayName" : "PTPN6 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48892,
    "identifier" : "P29351",
    "standardIdentifier" : "uniprot:P29351",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Ptpn6", "Hcp", "Hcph", "Ptp1C" ],
    "parents" : [ 10021673 ],
    "children" : [ ]
  }, {
    "dbId" : 10018569,
    "stId" : "R-MMU-447099",
    "displayName" : "Il2 [extracellular region]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48892,
    "diagramIds" : [ 119686 ],
    "identifier" : "P04351",
    "standardIdentifier" : "uniprot:P04351",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Il2" ],
    "parents" : [ 10018575, 10019163, 10019184 ],
    "children" : [ ]
  }, {
    "dbId" : 10018060,
    "stId" : "R-MMU-210620",
    "displayName" : "JAK2 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48892,
    "identifier" : "Q62120",
    "standardIdentifier" : "uniprot:Q62120",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Jak2" ],
    "parents" : [ 10019229 ],
    "children" : [ ]
  }, {
    "dbId" : 10101263,
    "stId" : "R-MMU-5673001",
    "displayName" : "RAF/MAP kinase cascade",
    "schemaClass" : "Pathway",
    "speciesId" : 48892,
    "diagramIds" : [ 119772 ]
  }, {
    "dbId" : 10018573,
    "stId" : "R-MMU-450046",
    "displayName" : "Il2ra [plasma membrane]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48892,
    "diagramIds" : [ 119687 ],
    "identifier" : "P01590",
    "standardIdentifier" : "uniprot:P01590",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Il2ra" ],
    "parents" : [ 10018575, 10019161, 10019184 ],
    "children" : [ ]
  }, {
    "dbId" : 10018575,
    "stId" : "R-MMU-538993",
    "displayName" : "IL2:IL2RA [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 48892,
    "diagramIds" : [ 119688 ],
    "parents" : [ 10018577 ],
    "children" : [ 10018573, 10018569 ]
  }, {
    "dbId" : 10012672,
    "stId" : "R-MMU-508241",
    "displayName" : "PI3K delta [cytosol]",
    "schemaClass" : "Complex",
    "speciesId" : 48892,
    "parents" : [ 10020126 ],
    "children" : [ 10012670, 9992954 ]
  }, {
    "dbId" : 9993217,
    "stId" : "R-MMU-58268",
    "displayName" : "SYK [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48892,
    "diagramIds" : [ 119740 ],
    "identifier" : "P48025",
    "standardIdentifier" : "uniprot:P48025",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Syk", "ptk72", "Sykb" ],
    "parents" : [ 10020156 ],
    "children" : [ ]
  }, {
    "dbId" : 10012674,
    "stId" : "R-MMU-437110",
    "displayName" : "PI3K beta [cytosol]",
    "schemaClass" : "Complex",
    "speciesId" : 48892,
    "parents" : [ 10020126 ],
    "children" : [ 9989239, 9992954 ]
  }, {
    "dbId" : 10020152,
    "stId" : "R-MMU-912535",
    "displayName" : "Interleukin receptor complexes with activated Shc:GRB2:p-GAB2:p85-containing Class 1 PI3Ks [plasma membrane]",
    "schemaClass" : "DefinedSet",
    "speciesId" : 48892,
    "diagramIds" : [ 119722 ],
    "parents" : [ ],
    "children" : [ 10020150, 10020142 ]
  }, {
    "dbId" : 10018106,
    "stId" : "R-MMU-451898",
    "displayName" : "JAK1 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48892,
    "diagramIds" : [ 119677 ],
    "identifier" : "P52332",
    "standardIdentifier" : "uniprot:P52332",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Jak1" ],
    "parents" : [ 10085301, 10018436 ],
    "children" : [ ]
  }, {
    "dbId" : 10020156,
    "stId" : "R-MMU-508449",
    "displayName" : "IL2:IL2R trimer:p-JAK1:JAK3:SYK [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 48892,
    "diagramIds" : [ 119741 ],
    "parents" : [ ],
    "children" : [ 9993217, 10019165 ]
  }, {
    "dbId" : 9678901,
    "stId" : "R-ALL-9678901",
    "displayName" : "ibrutinib [cytosol]",
    "schemaClass" : "ChemicalDrug",
    "speciesId" : 0,
    "identifier" : "6912",
    "standardIdentifier" : "iuphar.ligand:6912",
    "chebiIdentifier" : "chebi:76612",
    "parents" : [ 9678772 ],
    "children" : [ ]
  }, {
    "dbId" : 10020158,
    "stId" : "R-MMU-508438",
    "displayName" : "IL2:IL2R trimer:p-JAK1:JAK3:p-SYK [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 48892,
    "diagramIds" : [ 119744 ],
    "parents" : [ ],
    "children" : [ 10016096, 10019165 ]
  }, {
    "dbId" : 10020144,
    "stId" : "R-MMU-912532",
    "displayName" : "IL3:IL3R active complex, phosphorylated Bc:p(Y427,349,350)-SHC1:GRB2:p(Y)-GAB2:p85-containing Class 1A PI3Ks [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 48892,
    "parents" : [ 10020150 ],
    "children" : [ 10020132, 10020126 ]
  }, {
    "dbId" : 10020146,
    "stId" : "R-MMU-926773",
    "displayName" : "High affinity GM-CSF receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1:GRB2:p(Y)-GAB2:p85-containing Class 1A PI3Ks [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 48892,
    "parents" : [ 10020150 ],
    "children" : [ 10020134, 10020126 ]
  }, {
    "dbId" : 10020148,
    "stId" : "R-MMU-926774",
    "displayName" : "High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1:GRB2:p(Y)-GAB2:p85-containing Class 1A PI3Ks [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 48892,
    "parents" : [ 10020150 ],
    "children" : [ 10020126, 10020136 ]
  }, {
    "dbId" : 10020150,
    "stId" : "R-MMU-926776",
    "displayName" : "High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(Y593,628)- Bc:p(427,349,350)-SHC1:GRB2:p(Y)-GAB2:p85-containing Class 1A PI3Ks [plasma membrane]",
    "schemaClass" : "DefinedSet",
    "speciesId" : 48892,
    "parents" : [ 10020152 ],
    "children" : [ 10020148, 10020146, 10020144 ]
  }, {
    "dbId" : 10020136,
    "stId" : "R-MMU-926769",
    "displayName" : "High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1:GRB2:p(Y)-GAB2 [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 48892,
    "parents" : [ 10020148, 10020138 ],
    "children" : [ 10019267, 10020128 ]
  }, {
    "dbId" : 10021673,
    "stId" : "R-MMU-913378",
    "displayName" : "Interleukin receptor complexes with activated SHC1:SHIP1 [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 48892,
    "diagramIds" : [ 119731 ],
    "parents" : [ 10021675 ],
    "children" : [ 10006039, 10019271 ]
  }, {
    "dbId" : 10020138,
    "stId" : "R-MMU-926768",
    "displayName" : "High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(Y593,628)- Bc:p(427,349,350)-SHC1:GRB2:p(Y)-GAB2 [plasma membrane]",
    "schemaClass" : "DefinedSet",
    "speciesId" : 48892,
    "parents" : [ 10020140 ],
    "children" : [ 10020134, 10020132, 10020136 ]
  }, {
    "dbId" : 10021675,
    "stId" : "R-MMU-913411",
    "displayName" : "Interleukin receptor complexes with activated SHC1:SHIP:GRB2 [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 48892,
    "diagramIds" : [ 119732 ],
    "parents" : [ ],
    "children" : [ 9989218, 10021673 ]
  }, {
    "dbId" : 10020140,
    "stId" : "R-MMU-912533",
    "displayName" : "Interleukin receptor complexes with activated Shc:GRB2:p-GAB2 [plasma membrane]",
    "schemaClass" : "DefinedSet",
    "speciesId" : 48892,
    "diagramIds" : [ 119719 ],
    "parents" : [ ],
    "children" : [ 10020130, 10020138 ]
  }, {
    "dbId" : 10020142,
    "stId" : "R-MMU-508238",
    "displayName" : "IL2:IL2R trimer p(Y338) beta subunit:p-SHC:GRB2:GAB2:p85-containing Class 1A PI3Ks [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 48892,
    "parents" : [ 10020152 ],
    "children" : [ 10020130, 10020126 ]
  }, {
    "dbId" : 10020128,
    "stId" : "R-MMU-912528",
    "displayName" : "GRB2:p-Y-GAB2 [cytosol]",
    "schemaClass" : "Complex",
    "speciesId" : 48892,
    "parents" : [ 10020136, 10020134, 10020132, 10020130 ],
    "children" : [ 9989218, 9991546 ]
  }, {
    "dbId" : 113592,
    "stId" : "R-ALL-113592",
    "displayName" : "ATP [cytosol]",
    "schemaClass" : "SimpleEntity",
    "speciesId" : 0,
    "diagramIds" : [ 119698, 119717, 119765, 119734, 119708, 119743, 119758, 119694 ],
    "identifier" : "30616",
    "standardIdentifier" : "chebi:30616",
    "referenceType" : "ReferenceMolecule",
    "parents" : [ ],
    "children" : [ ]
  }, {
    "dbId" : 10021665,
    "stId" : "R-MMU-913354",
    "displayName" : "Inppl1 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48892,
    "identifier" : "Q6P549",
    "standardIdentifier" : "uniprot:Q6P549",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Inppl1", "Ship2" ],
    "parents" : [ 10021667 ],
    "children" : [ ]
  }, {
    "dbId" : 29370,
    "stId" : "R-ALL-29370",
    "displayName" : "ADP [cytosol]",
    "schemaClass" : "SimpleEntity",
    "speciesId" : 0,
    "diagramIds" : [ 119745, 119696, 119699, 119767, 119735, 119718, 119709, 119759 ],
    "identifier" : "456216",
    "standardIdentifier" : "chebi:456216",
    "referenceType" : "ReferenceMolecule",
    "parents" : [ ],
    "children" : [ ]
  }, {
    "dbId" : 10020130,
    "stId" : "R-MMU-912523",
    "displayName" : "IL2:IL2R trimer p(Y338,392,510) beta subunit:p-SHC:GRB2:p(Y)-GAB2 [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 48892,
    "parents" : [ 10020142, 10020140 ],
    "children" : [ 10019207, 10020128 ]
  }, {
    "dbId" : 10021667,
    "stId" : "R-MMU-913467",
    "displayName" : "SHIP1,2 [cytosol]",
    "schemaClass" : "DefinedSet",
    "speciesId" : 48892,
    "diagramIds" : [ 119727 ],
    "parents" : [ 10021669 ],
    "children" : [ 10021665, 10004400 ]
  }, {
    "dbId" : 10020132,
    "stId" : "R-MMU-912540",
    "displayName" : "IL3:IL3R active complex, phosphorylated Bc:p(Y427,349,350)-SHC1:GRB2:p(Y)-GAB2 [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 48892,
    "parents" : [ 10020144, 10020138 ],
    "children" : [ 10019285, 10020128 ]
  }, {
    "dbId" : 10021669,
    "stId" : "R-MMU-913393",
    "displayName" : "Interleukin receptor complexes with activated SHC1:SHIP1,2 [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 48892,
    "diagramIds" : [ 119728 ],
    "parents" : [ ],
    "children" : [ 10019271, 10021667 ]
  }, {
    "dbId" : 10020134,
    "stId" : "R-MMU-926770",
    "displayName" : "High affinity GM-CSF receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1:GRB2:p(Y)-GAB2 [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 48892,
    "parents" : [ 10020146, 10020138 ],
    "children" : [ 10019251, 10020128 ]
  }, {
    "dbId" : 10019161,
    "stId" : "R-MMU-451918",
    "displayName" : "IL2RA:IL2RB:p-JAK1 [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 48892,
    "parents" : [ 10019163 ],
    "children" : [ 10019159, 10018573 ]
  }, {
    "dbId" : 10019163,
    "stId" : "R-MMU-451939",
    "displayName" : "IL2RA:IL2RB:p-JAK1:IL2 [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 48892,
    "parents" : [ 10019165 ],
    "children" : [ 10019161, 10018569 ]
  }, {
    "dbId" : 10019165,
    "stId" : "R-MMU-451920",
    "displayName" : "IL2:IL2R trimer:p-JAK1:JAK3 [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 48892,
    "diagramIds" : [ 119695 ],
    "parents" : [ 10020158, 10020156 ],
    "children" : [ 10019163, 10018442 ]
  }, {
    "dbId" : 10019157,
    "stId" : "R-MMU-451921",
    "displayName" : "phospho-p-Y-JAK1 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48892,
    "identifier" : "P52332",
    "standardIdentifier" : "uniprot:P52332",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Jak1" ],
    "parents" : [ 10085331, 10019159, 10019209, 10019184 ],
    "children" : [ ]
  }, {
    "dbId" : 10019159,
    "stId" : "R-MMU-451943",
    "displayName" : "IL2RB:p-JAK1 [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 48892,
    "parents" : [ 10019161 ],
    "children" : [ 10019157, 10018434 ]
  }, {
    "dbId" : 10020169,
    "stId" : "R-MMU-508512",
    "displayName" : "JAK3:PYK2 [cytosol]",
    "schemaClass" : "Complex",
    "speciesId" : 48892,
    "diagramIds" : [ 119748 ],
    "parents" : [ ],
    "children" : [ 10013324, 10018440 ]
  }, {
    "dbId" : 10020172,
    "stId" : "R-MMU-508515",
    "displayName" : "phospho-p-Y-PTK2B [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48892,
    "identifier" : "Q9QVP9",
    "standardIdentifier" : "uniprot:Q9QVP9",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 10020174 ],
    "children" : [ ]
  }, {
    "dbId" : 10019150,
    "stId" : "R-MMU-9678869",
    "displayName" : "JAK3:JAK3 inhibitors [cytosol]",
    "schemaClass" : "Complex",
    "speciesId" : 48892,
    "diagramIds" : [ 119684 ],
    "parents" : [ ],
    "children" : [ 9678772, 10018440 ]
  }, {
    "dbId" : 10020174,
    "stId" : "R-MMU-508510",
    "displayName" : "JAK3:p-PYK2 [cytosol]",
    "schemaClass" : "Complex",
    "speciesId" : 48892,
    "diagramIds" : [ 119750 ],
    "parents" : [ ],
    "children" : [ 10020172, 10018440 ]
  }, {
    "dbId" : 10028352,
    "stId" : "R-MMU-914048",
    "displayName" : "phospho-Stat3 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48892,
    "identifier" : "P42227",
    "standardIdentifier" : "uniprot:P42227",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Stat3", "Aprf" ],
    "parents" : [ 10085345 ],
    "children" : [ ]
  }, {
    "dbId" : 10020932,
    "stId" : "R-MMU-873791",
    "displayName" : "phospho-Stat1 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48892,
    "identifier" : "P42225",
    "standardIdentifier" : "uniprot:P42225",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Stat1" ],
    "parents" : [ 10085345 ],
    "children" : [ ]
  }, {
    "dbId" : 10019192,
    "stId" : "R-MMU-452107",
    "displayName" : "IL2:IL2R trimer p-(Y338,392,510) beta subunit:p-JAK1:JAK3:STAT5 [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 48892,
    "diagramIds" : [ 119706 ],
    "parents" : [ ],
    "children" : [ 10019190, 10019184 ]
  }, {
    "dbId" : 10012026,
    "stId" : "R-MMU-539044",
    "displayName" : "Stat3 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48892,
    "identifier" : "P42227",
    "standardIdentifier" : "uniprot:P42227",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Stat3", "Aprf" ],
    "parents" : [ 10085339 ],
    "children" : [ ]
  }, {
    "dbId" : 10019194,
    "stId" : "R-MMU-507936",
    "displayName" : "phospho-Stat5a [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48892,
    "identifier" : "P42230",
    "standardIdentifier" : "uniprot:P42230",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Stat5a", "Mgf", "Mpf" ],
    "parents" : [ 10085343, 10019198 ],
    "children" : [ ]
  }, {
    "dbId" : 9991546,
    "stId" : "R-MMU-912529",
    "displayName" : "phospho-Gab2 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48892,
    "identifier" : "Q9Z1S8",
    "standardIdentifier" : "uniprot:Q9Z1S8",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Gab2" ],
    "parents" : [ 10020128 ],
    "children" : [ ]
  }, {
    "dbId" : 9678960,
    "stId" : "R-ALL-9678960",
    "displayName" : "acalabrutinib [cytosol]",
    "schemaClass" : "ChemicalDrug",
    "speciesId" : 0,
    "identifier" : "8912",
    "standardIdentifier" : "iuphar.ligand:8912",
    "chebiIdentifier" : "chebi:167707",
    "parents" : [ 9678772 ],
    "children" : [ ]
  }, {
    "dbId" : 10019196,
    "stId" : "R-MMU-507939",
    "displayName" : "phospho-Stat5b [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48892,
    "identifier" : "P42232",
    "standardIdentifier" : "uniprot:P42232",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Stat5b" ],
    "parents" : [ 10085343, 10019198 ],
    "children" : [ ]
  }, {
    "dbId" : 10012029,
    "stId" : "R-MMU-380747",
    "displayName" : "Stat5a [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48892,
    "identifier" : "P42230",
    "standardIdentifier" : "uniprot:P42230",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Stat5a", "Mgf", "Mpf" ],
    "parents" : [ 10084810, 10019190 ],
    "children" : [ ]
  }, {
    "dbId" : 10019198,
    "stId" : "R-MMU-507929",
    "displayName" : "p-STAT5A, p-STAT5B [cytosol]",
    "schemaClass" : "DefinedSet",
    "speciesId" : 48892,
    "diagramIds" : [ 119738 ],
    "parents" : [ 10019200 ],
    "children" : [ 10019196, 10019194 ]
  }, {
    "dbId" : 10019184,
    "stId" : "R-MMU-452119",
    "displayName" : "IL2:IL2R trimer p-(Y338,392,510) beta subunit:p-JAK1:JAK3 [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 48892,
    "diagramIds" : [ 119700 ],
    "parents" : [ 10019192, 10019200, 10019186, 10019207 ],
    "children" : [ 10019157, 10019182, 10018573, 10018442, 10018569 ]
  }, {
    "dbId" : 9989233,
    "stId" : "R-MMU-74791",
    "displayName" : "Pik3r2 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48892,
    "identifier" : "O08908",
    "standardIdentifier" : "uniprot:O08908",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Pik3r2" ],
    "parents" : [ 9992954 ],
    "children" : [ ]
  }, {
    "dbId" : 10019186,
    "stId" : "R-MMU-452095",
    "displayName" : "IL2:IL2R trimer p-(Y338,392,510)-beta subunit:p-JAK1:JAK3:SHC [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 48892,
    "diagramIds" : [ 119703 ],
    "parents" : [ ],
    "children" : [ 9989250, 10019184 ]
  }, {
    "dbId" : 10004341,
    "stId" : "R-MMU-167609",
    "displayName" : "LCK [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48892,
    "identifier" : "P06240",
    "standardIdentifier" : "uniprot:P06240",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Lck", "Lsk-t" ],
    "parents" : [ 10019209 ],
    "children" : [ ]
  }, {
    "dbId" : 10019190,
    "stId" : "R-MMU-452094",
    "displayName" : "STAT5A,STAT5B [cytosol]",
    "schemaClass" : "DefinedSet",
    "speciesId" : 48892,
    "diagramIds" : [ 119705 ],
    "parents" : [ 10019192 ],
    "children" : [ 10012032, 10012029 ]
  }, {
    "dbId" : 9989239,
    "stId" : "R-MMU-74788",
    "displayName" : "Pik3cb [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48892,
    "identifier" : "Q8BTI9",
    "standardIdentifier" : "uniprot:Q8BTI9",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Pik3cb" ],
    "parents" : [ 10012674 ],
    "children" : [ ]
  }, {
    "dbId" : 10019182,
    "stId" : "R-MMU-452093",
    "displayName" : "phospho-Il2rb [plasma membrane]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48892,
    "identifier" : "P16297",
    "standardIdentifier" : "uniprot:P16297",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Il2rb" ],
    "parents" : [ 10019184 ],
    "children" : [ ]
  }, {
    "dbId" : 9989230,
    "stId" : "R-MMU-74789",
    "displayName" : "Pik3r1 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48892,
    "identifier" : "P26450",
    "standardIdentifier" : "uniprot:P26450",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Pik3r1" ],
    "parents" : [ 9992954 ],
    "children" : [ ]
  }, {
    "dbId" : 10016096,
    "stId" : "R-MMU-429432",
    "displayName" : "phospho-p-Y-SYK [plasma membrane]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48892,
    "identifier" : "P48025",
    "standardIdentifier" : "uniprot:P48025",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Syk", "ptk72", "Sykb" ],
    "parents" : [ 10020158 ],
    "children" : [ ]
  }, {
    "dbId" : 9989218,
    "stId" : "R-MMU-74686",
    "displayName" : "Grb2 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48892,
    "diagramIds" : [ 119730 ],
    "identifier" : "Q60631",
    "standardIdentifier" : "uniprot:Q60631",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Grb2" ],
    "parents" : [ 9989223, 10020128, 10019273, 10021675 ],
    "children" : [ ]
  }, {
    "dbId" : 9989221,
    "stId" : "R-MMU-64847",
    "displayName" : "Sos1 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48892,
    "identifier" : "Q62245",
    "standardIdentifier" : "uniprot:Q62245",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Sos1" ],
    "parents" : [ 9989223 ],
    "children" : [ ]
  }, {
    "dbId" : 9989223,
    "stId" : "R-MMU-109797",
    "displayName" : "GRB2-1:SOS1 [cytosol]",
    "schemaClass" : "Complex",
    "speciesId" : 48892,
    "diagramIds" : [ 119724 ],
    "parents" : [ 10019299 ],
    "children" : [ 9989218, 9989221 ]
  } ],
  "edges" : [ {
    "dbId" : 10085337,
    "stId" : "R-MMU-9006850",
    "displayName" : "IL21 receptor JAK phosphorylation",
    "schemaClass" : "BlackBoxEvent",
    "speciesId" : 0,
    "preceding" : [ 10085327 ],
    "following" : [ 10085351 ],
    "inputs" : [ 113592, 10085325 ],
    "outputs" : [ 10085335, 29370 ],
    "efs" : [ ],
    "diagramIds" : [ 119757 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10018585,
    "stId" : "R-MMU-450063",
    "displayName" : "Interleukin-2: IL2 receptor alpha:beta binds IL2 receptor gamma subunit",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "preceding" : [ 10018579, 10019152 ],
    "following" : [ 10019168 ],
    "inputs" : [ 10018577, 10018442 ],
    "outputs" : [ 10018583 ],
    "efs" : [ ],
    "diagramIds" : [ 119691 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10019152,
    "stId" : "R-MMU-451895",
    "displayName" : "IL2RG binds JAK3",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "following" : [ 10085327, 10018585 ],
    "inputs" : [ 539020, 10018440 ],
    "outputs" : [ 10018442 ],
    "efs" : [ ],
    "inhibitors" : [ 10019150 ],
    "diagramIds" : [ 119680 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10020176,
    "stId" : "R-MMU-508451",
    "displayName" : "PTK2B is phosphorylated",
    "schemaClass" : "BlackBoxEvent",
    "speciesId" : 0,
    "preceding" : [ 10020180 ],
    "inputs" : [ 10020169 ],
    "outputs" : [ 10020174 ],
    "efs" : [ ],
    "diagramIds" : [ 119749 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10019217,
    "stId" : "R-MMU-452122",
    "displayName" : "JAK1 phosphorylates Y338, Y392 and Y510 of IL2RB",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "preceding" : [ 10019168 ],
    "following" : [ 10019214, 10019188 ],
    "inputs" : [ 113592, 10019165 ],
    "outputs" : [ 29370, 10019184 ],
    "catalysts" : [ 10019165 ],
    "efs" : [ ],
    "diagramIds" : [ 119697 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10019155,
    "stId" : "R-MMU-451900",
    "displayName" : "IL2RB binds JAK1",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "following" : [ 10018579 ],
    "inputs" : [ 10018434, 10018106 ],
    "outputs" : [ 10018436 ],
    "efs" : [ ],
    "diagramIds" : [ 119676 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10018579,
    "stId" : "R-MMU-450027",
    "displayName" : "Interleukin-2 receptor alpha:IL2 binds Interleukin-2 receptor beta",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "preceding" : [ 10018581, 10019155 ],
    "following" : [ 10018585 ],
    "inputs" : [ 10018436, 10018575 ],
    "outputs" : [ 10018577 ],
    "efs" : [ ],
    "diagramIds" : [ 119689 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10020180,
    "stId" : "R-MMU-508513",
    "displayName" : "PTK2B binds JAK3",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "following" : [ 10020176 ],
    "inputs" : [ 10013324, 10018440 ],
    "outputs" : [ 10020169 ],
    "efs" : [ ],
    "diagramIds" : [ 119746 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10018581,
    "stId" : "R-MMU-450054",
    "displayName" : "Interleukin-2 receptor alpha binds interleukin-2",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "following" : [ 10018579 ],
    "inputs" : [ 10018573, 10018569 ],
    "outputs" : [ 10018575 ],
    "efs" : [ ],
    "diagramIds" : [ 119685 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10021577,
    "stId" : "R-MMU-912527",
    "displayName" : "SHC1 mediates cytokine-induced phosphorylation of GAB2",
    "schemaClass" : "BlackBoxEvent",
    "speciesId" : 0,
    "preceding" : [ 10019297 ],
    "following" : [ 10020154 ],
    "inputs" : [ 113592, 10019295 ],
    "outputs" : [ 29370, 10020140 ],
    "efs" : [ ],
    "diagramIds" : [ 119716 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10019212,
    "stId" : "R-MMU-452100",
    "displayName" : "SHC1 bound to IL2 receptor is phosphorylated",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "preceding" : [ 10019188 ],
    "following" : [ 10021671, 10019297, 10019301 ],
    "inputs" : [ 10019186, 113592 ],
    "outputs" : [ 10019207, 29370 ],
    "catalysts" : [ 10019209 ],
    "efs" : [ ],
    "diagramIds" : [ 119707 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10085327,
    "stId" : "R-MMU-9006844",
    "displayName" : "IL21:IL21R:JAK1 binds IL2RG:JAK3",
    "schemaClass" : "BlackBoxEvent",
    "speciesId" : 0,
    "preceding" : [ 10019152, 10085305 ],
    "following" : [ 10085337 ],
    "inputs" : [ 10085303, 10018442 ],
    "outputs" : [ 10085325 ],
    "efs" : [ ],
    "diagramIds" : [ 119755 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10019214,
    "stId" : "R-MMU-452108",
    "displayName" : "Phosphorylation of IL2RB Y338, Y392 or Y510 enables STAT recruitment",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "preceding" : [ 10019217 ],
    "following" : [ 10019203 ],
    "inputs" : [ 10019190, 10019184 ],
    "outputs" : [ 10019192 ],
    "efs" : [ ],
    "diagramIds" : [ 119704 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10020161,
    "stId" : "R-MMU-508282",
    "displayName" : "SYK is a substrate for JAK1",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "preceding" : [ 10020163 ],
    "inputs" : [ 113592, 10020156 ],
    "outputs" : [ 29370, 10020158 ],
    "catalysts" : [ 10020156 ],
    "efs" : [ ],
    "diagramIds" : [ 119742 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10022530,
    "stId" : "R-MMU-919404",
    "displayName" : "Phosphorylated STAT5 is released",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "preceding" : [ 10019203 ],
    "inputs" : [ 10019200 ],
    "outputs" : [ 10019184, 10019198 ],
    "efs" : [ ],
    "diagramIds" : [ 119737 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10019203,
    "stId" : "R-MMU-452097",
    "displayName" : "Recruited STAT5 is phosphorylated",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "preceding" : [ 10019214 ],
    "following" : [ 10022530 ],
    "inputs" : [ 113592, 10019192 ],
    "outputs" : [ 29370, 10019200 ],
    "catalysts" : [ 10019192 ],
    "efs" : [ ],
    "diagramIds" : [ 119733 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10020163,
    "stId" : "R-MMU-508292",
    "displayName" : "SYK binds IL2RB",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "preceding" : [ 10019168 ],
    "following" : [ 10020161 ],
    "inputs" : [ 9993217, 10019165 ],
    "outputs" : [ 10020156 ],
    "efs" : [ ],
    "diagramIds" : [ 119739 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10085305,
    "stId" : "R-MMU-9005980",
    "displayName" : "IL21 binds IL21R:JAK1",
    "schemaClass" : "BlackBoxEvent",
    "speciesId" : 0,
    "following" : [ 10085327 ],
    "inputs" : [ 10085301, 10085295 ],
    "outputs" : [ 10085303 ],
    "efs" : [ ],
    "diagramIds" : [ 119751 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10020154,
    "stId" : "R-MMU-508247",
    "displayName" : "Gab2 binds the p85 subunit of Class 1A PI3 kinases",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "preceding" : [ 10021577 ],
    "inputs" : [ 10020126, 10020140 ],
    "outputs" : [ 10020152 ],
    "efs" : [ ],
    "diagramIds" : [ 119720 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10089777,
    "stId" : "R-MMU-9679028",
    "displayName" : "JAK3 binds JAK3 inhibitors",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "inputs" : [ 9678772, 10018440 ],
    "outputs" : [ 10019150 ],
    "efs" : [ ],
    "diagramIds" : [ 119768 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10019188,
    "stId" : "R-MMU-452091",
    "displayName" : "Phosphorylation of IL2RB Y338 enables SHC recruitment",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "preceding" : [ 10019217 ],
    "following" : [ 10019212 ],
    "inputs" : [ 9989250, 10019184 ],
    "outputs" : [ 10019186 ],
    "efs" : [ ],
    "diagramIds" : [ 119701 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10021677,
    "stId" : "R-MMU-913424",
    "displayName" : "The SHC1:SHIP1 complex is stabilized by GRB2",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "preceding" : [ 10021671 ],
    "inputs" : [ 9989218, 10021673 ],
    "outputs" : [ 10021675 ],
    "efs" : [ ],
    "diagramIds" : [ 119729 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10019168,
    "stId" : "R-MMU-451942",
    "displayName" : "Within the IL-2R complex JAK3 phosphorylates JAK1",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "preceding" : [ 10018585 ],
    "following" : [ 10020163, 10019217 ],
    "inputs" : [ 10018583, 113592 ],
    "outputs" : [ 29370, 10019165 ],
    "catalysts" : [ 10018583 ],
    "efs" : [ ],
    "diagramIds" : [ 119693 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10019297,
    "stId" : "R-MMU-453104",
    "displayName" : "Phosphorylated SHC1 recruits GRB2:GAB2",
    "schemaClass" : "BlackBoxEvent",
    "speciesId" : 0,
    "preceding" : [ 10019212 ],
    "following" : [ 10021577 ],
    "inputs" : [ 10019271, 10019273 ],
    "outputs" : [ 10019295 ],
    "efs" : [ ],
    "diagramIds" : [ 119712 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10085349,
    "stId" : "R-MMU-9006870",
    "displayName" : "IL21 receptor STAT phosphorylation",
    "schemaClass" : "BlackBoxEvent",
    "speciesId" : 0,
    "preceding" : [ 10085351 ],
    "inputs" : [ 113592, 10085341 ],
    "outputs" : [ 29370, 10085347 ],
    "efs" : [ ],
    "diagramIds" : [ 119764 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10019301,
    "stId" : "R-MMU-453111",
    "displayName" : "Phosphorylated SHC recruits GRB2:SOS1",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "preceding" : [ 10019212 ],
    "inputs" : [ 9989223, 10019271 ],
    "outputs" : [ 10019299 ],
    "efs" : [ ],
    "diagramIds" : [ 119723 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10085351,
    "stId" : "R-MMU-9006873",
    "displayName" : "IL21 receptor STAT binding",
    "schemaClass" : "BlackBoxEvent",
    "speciesId" : 0,
    "preceding" : [ 10085337 ],
    "following" : [ 10085349 ],
    "inputs" : [ 10085335, 10085339 ],
    "outputs" : [ 10085341 ],
    "efs" : [ ],
    "diagramIds" : [ 119761 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10021671,
    "stId" : "R-MMU-913374",
    "displayName" : "Phosphorylated SHC1 recruits SHIP",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "preceding" : [ 10019212 ],
    "following" : [ 10021677 ],
    "inputs" : [ 10019271, 10021667 ],
    "outputs" : [ 10021669 ],
    "efs" : [ ],
    "diagramIds" : [ 119726 ],
    "entityFunctionalStatus" : [ ]
  } ],
  "subpathways" : [ {
    "dbId" : 10100417,
    "stId" : "R-MMU-912526",
    "displayName" : "Interleukin receptor SHC signaling",
    "events" : [ 10021577, 10020154, 10021677, 10019297, 10019301, 10021671 ]
  }, {
    "dbId" : 10100385,
    "stId" : "R-MMU-9020558",
    "displayName" : "Interleukin-2 signaling",
    "events" : [ 10018585, 10019152, 10089777, 10020176, 10019217, 10019155, 10018579, 10019188, 10020180, 10018581, 10019212, 10019214, 10019168, 10020161, 10022530, 10019203, 10020163 ]
  }, {
    "dbId" : 10101629,
    "stId" : "R-MMU-9020958",
    "displayName" : "Interleukin-21 signaling",
    "events" : [ 10085305, 10085337, 10085327, 10085349, 10085351 ]
  } ]
}