{ "dbId" : 10099951, "stableId" : "R-MMU-199992", "displayName" : "trans-Golgi Network Vesicle Budding", "nodes" : [ { "id" : 30976, "reactomeId" : 10008011, "displayName" : "Arf1-GDP", "schemaClass" : "Complex", "renderableClass" : "Complex", "position" : { "x" : 50, "y" : 805 }, "minX" : 17, "maxX" : 135, "minY" : 788, "maxY" : 816, "prop" : { "x" : 17, "y" : 794, "width" : 66, "height" : 22 }, "textPosition" : { "x" : 18, "y" : 795 }, "bgColor" : { "r" : 204, "g" : 255, "b" : 255 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 83, "y" : 794 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 83, "y" : 794 } } }, "connectors" : [ { "edgeId" : 30974, "type" : "INPUT", "segments" : [ { "from" : { "x" : 86, "y" : 805 }, "to" : { "x" : 135, "y" : 805 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 30977, "reactomeId" : 29420, "displayName" : "GDP", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 248, "y" : 772 }, "minX" : 203, "maxX" : 270, "minY" : 756, "maxY" : 807, "prop" : { "x" : 227, "y" : 757, "width" : 42, "height" : 30 }, "textPosition" : { "x" : 231, "y" : 761 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 264, "y" : 762 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 264, "y" : 762 } } }, "connectors" : [ { "edgeId" : 30974, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 228, "y" : 790 }, "to" : { "x" : 203, "y" : 807 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 225, "y" : 797 }, "b" : { "x" : 228, "y" : 790 }, "c" : { "x" : 220, "y" : 791 }, "type" : "ARROW", "centre" : { "x" : 220, "y" : 791 } } } ] }, { "id" : 30978, "reactomeId" : 10008015, "displayName" : "Arf1-GTP", "schemaClass" : "Complex", "renderableClass" : "Complex", "position" : { "x" : 273, "y" : 852 }, "minX" : 203, "maxX" : 312, "minY" : 807, "maxY" : 863, "prop" : { "x" : 241, "y" : 841, "width" : 65, "height" : 22 }, "textPosition" : { "x" : 243, "y" : 842 }, "bgColor" : { "r" : 204, "g" : 255, "b" : 255 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 306, "y" : 841 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 306, "y" : 841 } } }, "connectors" : [ { "edgeId" : 30974, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 255, "y" : 838 }, "to" : { "x" : 203, "y" : 807 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 247, "y" : 838 }, "b" : { "x" : 255, "y" : 838 }, "c" : { "x" : 251, "y" : 831 }, "type" : "ARROW", "centre" : { "x" : 251, "y" : 831 } } } ] }, { "id" : 30979, "reactomeId" : 10008019, "displayName" : "Gbf1", "schemaClass" : "EntityWithAccessionedSequence", "renderableClass" : "Protein", "position" : { "x" : 163, "y" : 857 }, "minX" : 144, "maxX" : 189, "minY" : 813, "maxY" : 868, "prop" : { "x" : 144, "y" : 846, "width" : 39, "height" : 22 }, "textPosition" : { "x" : 145, "y" : 846 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 183, "y" : 846 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 183, "y" : 846 } } }, "connectors" : [ { "edgeId" : 30974, "type" : "CATALYST", "segments" : [ { "from" : { "x" : 163, "y" : 843 }, "to" : { "x" : 164, "y" : 821 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "c" : { "x" : 164, "y" : 817 }, "r" : 4, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 164, "y" : 817 } } } ] }, { "id" : 30981, "reactomeId" : 10008015, "displayName" : "Arf1-GTP", "schemaClass" : "Complex", "renderableClass" : "Complex", "position" : { "x" : 1219, "y" : 979 }, "minX" : 1187, "maxX" : 1489, "minY" : 752, "maxY" : 990, "prop" : { "x" : 1187, "y" : 968, "width" : 65, "height" : 22 }, "textPosition" : { "x" : 1189, "y" : 969 }, "bgColor" : { "r" : 204, "g" : 255, "b" : 255 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1252, "y" : 968 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1252, "y" : 968 } } }, "connectors" : [ { "edgeId" : 30980, "type" : "INPUT", "segments" : [ { "from" : { "x" : 1236, "y" : 965 }, "to" : { "x" : 1489, "y" : 807 } } ], "stoichiometry" : { "value" : 1 } }, { "edgeId" : 31037, "type" : "INPUT", "segments" : [ { "from" : { "x" : 1227, "y" : 965 }, "to" : { "x" : 1290, "y" : 890 } }, { "from" : { "x" : 1290, "y" : 890 }, "to" : { "x" : 1347, "y" : 752 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 30982, "reactomeId" : 10016791, "displayName" : "Lysosome Destined Cargo", "schemaClass" : "CandidateSet", "renderableClass" : "EntitySet", "position" : { "x" : 1452, "y" : 908 }, "minX" : 1390, "maxX" : 1514, "minY" : 807, "maxY" : 926, "prop" : { "x" : 1390, "y" : 890, "width" : 124, "height" : 36 }, "textPosition" : { "x" : 1399, "y" : 890 }, "connectors" : [ { "edgeId" : 30980, "type" : "INPUT", "segments" : [ { "from" : { "x" : 1456, "y" : 884 }, "to" : { "x" : 1470, "y" : 830 } }, { "from" : { "x" : 1470, "y" : 830 }, "to" : { "x" : 1489, "y" : 807 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 30983, "reactomeId" : 10016781, "displayName" : "Lysosome Destined Cargo", "schemaClass" : "CandidateSet", "renderableClass" : "EntitySet", "position" : { "x" : 1554, "y" : 853 }, "minX" : 1489, "maxX" : 1616, "minY" : 807, "maxY" : 871, "prop" : { "x" : 1492, "y" : 835, "width" : 124, "height" : 36 }, "textPosition" : { "x" : 1501, "y" : 835 }, "connectors" : [ { "edgeId" : 30980, "type" : "INPUT", "segments" : [ { "from" : { "x" : 1528, "y" : 829 }, "to" : { "x" : 1489, "y" : 807 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 30984, "reactomeId" : 5632461, "displayName" : "Arrb1", "schemaClass" : "EntityWithAccessionedSequence", "renderableClass" : "Protein", "position" : { "x" : 1440, "y" : 775 }, "minX" : 1347, "maxX" : 1489, "minY" : 752, "maxY" : 807, "prop" : { "x" : 1416, "y" : 764, "width" : 48, "height" : 22 }, "textPosition" : { "x" : 1419, "y" : 764 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1464, "y" : 764 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1464, "y" : 764 } } }, "connectors" : [ { "edgeId" : 30980, "type" : "INPUT", "segments" : [ { "from" : { "x" : 1456, "y" : 789 }, "to" : { "x" : 1489, "y" : 807 } } ], "stoichiometry" : { "value" : 1 } }, { "edgeId" : 31037, "type" : "INPUT", "segments" : [ { "from" : { "x" : 1413, "y" : 769 }, "to" : { "x" : 1347, "y" : 752 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 30985, "reactomeId" : 10014929, "displayName" : "Vamp", "schemaClass" : "CandidateSet", "renderableClass" : "EntitySet", "position" : { "x" : 1339, "y" : 859 }, "minX" : 1318, "maxX" : 1489, "minY" : 752, "maxY" : 870, "prop" : { "x" : 1318, "y" : 848, "width" : 43, "height" : 22 }, "textPosition" : { "x" : 1318, "y" : 848 }, "connectors" : [ { "edgeId" : 30980, "type" : "INPUT", "segments" : [ { "from" : { "x" : 1367, "y" : 851 }, "to" : { "x" : 1489, "y" : 807 } } ], "stoichiometry" : { "value" : 1 } }, { "edgeId" : 31037, "type" : "INPUT", "segments" : [ { "from" : { "x" : 1339, "y" : 842 }, "to" : { "x" : 1347, "y" : 752 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 30986, "reactomeId" : 10015069, "displayName" : "AP-1 Complex", "schemaClass" : "Complex", "renderableClass" : "Complex", "position" : { "x" : 1542, "y" : 752 }, "minX" : 1347, "maxX" : 1595, "minY" : 735, "maxY" : 807, "prop" : { "x" : 1495, "y" : 741, "width" : 94, "height" : 22 }, "textPosition" : { "x" : 1496, "y" : 742 }, "bgColor" : { "r" : 204, "g" : 255, "b" : 255 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1589, "y" : 741 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1589, "y" : 741 } } }, "connectors" : [ { "edgeId" : 30980, "type" : "INPUT", "segments" : [ { "from" : { "x" : 1531, "y" : 766 }, "to" : { "x" : 1489, "y" : 807 } } ], "stoichiometry" : { "value" : 1 } }, { "edgeId" : 31037, "type" : "INPUT", "segments" : [ { "from" : { "x" : 1492, "y" : 752 }, "to" : { "x" : 1347, "y" : 752 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 30987, "reactomeId" : 10016793, "displayName" : "Lysosome Destined Cargo:AP-1:Arf1-GTP:beta-Arrestin-1:Vamp Complex", "schemaClass" : "Complex", "renderableClass" : "Complex", "position" : { "x" : 1704, "y" : 852 }, "minX" : 1642, "maxX" : 1772, "minY" : 686, "maxY" : 884, "prop" : { "x" : 1642, "y" : 820, "width" : 124, "height" : 64 }, "textPosition" : { "x" : 1649, "y" : 807 }, "bgColor" : { "r" : 204, "g" : 255, "b" : 255 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1766, "y" : 820 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1766, "y" : 820 } } }, "connectors" : [ { "edgeId" : 30980, "type" : "OUTPUT", "segments" : [ ], "stoichiometry" : { "value" : 1 } }, { "edgeId" : 30988, "type" : "INPUT", "segments" : [ { "from" : { "x" : 1714, "y" : 817 }, "to" : { "x" : 1758, "y" : 686 } } ], "stoichiometry" : { "value" : 52, "shape" : { "a" : { "x" : 1730, "y" : 745 }, "b" : { "x" : 1742, "y" : 757 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 1736, "y" : 751 } } } } ] }, { "id" : 30989, "reactomeId" : 10015039, "displayName" : "DNM2", "schemaClass" : "EntityWithAccessionedSequence", "renderableClass" : "Protein", "position" : { "x" : 1838, "y" : 646 }, "minX" : 1758, "maxX" : 2013, "minY" : 629, "maxY" : 686, "prop" : { "x" : 1816, "y" : 635, "width" : 45, "height" : 22 }, "textPosition" : { "x" : 1816, "y" : 635 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1861, "y" : 635 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1861, "y" : 635 } } }, "connectors" : [ { "edgeId" : 30988, "type" : "INPUT", "segments" : [ { "from" : { "x" : 1816, "y" : 660 }, "to" : { "x" : 1758, "y" : 686 } } ], "stoichiometry" : { "value" : 1 } }, { "edgeId" : 30995, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 1864, "y" : 648 }, "to" : { "x" : 2013, "y" : 665 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 1871, "y" : 645 }, "b" : { "x" : 1864, "y" : 648 }, "c" : { "x" : 1870, "y" : 653 }, "type" : "ARROW", "centre" : { "x" : 1870, "y" : 653 } } } ] }, { "id" : 30990, "reactomeId" : 9999928, "displayName" : "Sh3gl2", "schemaClass" : "EntityWithAccessionedSequence", "renderableClass" : "Protein", "position" : { "x" : 1794, "y" : 605 }, "minX" : 1758, "maxX" : 2013, "minY" : 588, "maxY" : 686, "prop" : { "x" : 1767, "y" : 594, "width" : 55, "height" : 22 }, "textPosition" : { "x" : 1769, "y" : 594 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1822, "y" : 594 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1822, "y" : 594 } } }, "connectors" : [ { "edgeId" : 30988, "type" : "INPUT", "segments" : [ { "from" : { "x" : 1789, "y" : 619 }, "to" : { "x" : 1758, "y" : 686 } } ], "stoichiometry" : { "value" : 1 } }, { "edgeId" : 30995, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 1825, "y" : 612 }, "to" : { "x" : 2013, "y" : 665 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 1833, "y" : 610 }, "b" : { "x" : 1825, "y" : 612 }, "c" : { "x" : 1831, "y" : 618 }, "type" : "ARROW", "centre" : { "x" : 1831, "y" : 618 } } } ] }, { "id" : 30991, "reactomeId" : 10015037, "displayName" : "Clathrin Triskelion", "schemaClass" : "Complex", "renderableClass" : "Complex", "position" : { "x" : 1634, "y" : 701 }, "minX" : 971, "maxX" : 1758, "minY" : 684, "maxY" : 715, "prop" : { "x" : 1578, "y" : 690, "width" : 113, "height" : 22 }, "textPosition" : { "x" : 1601, "y" : 677 }, "bgColor" : { "r" : 204, "g" : 255, "b" : 255 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1691, "y" : 690 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1691, "y" : 690 } } }, "connectors" : [ { "edgeId" : 31041, "type" : "INPUT", "segments" : [ { "from" : { "x" : 1575, "y" : 702 }, "to" : { "x" : 971, "y" : 715 } } ], "stoichiometry" : { "value" : 48, "shape" : { "a" : { "x" : 1267, "y" : 702 }, "b" : { "x" : 1279, "y" : 714 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 1273, "y" : 708 } } } }, { "edgeId" : 30988, "type" : "INPUT", "segments" : [ { "from" : { "x" : 1694, "y" : 694 }, "to" : { "x" : 1758, "y" : 686 } } ], "stoichiometry" : { "value" : 48, "shape" : { "a" : { "x" : 1720, "y" : 684 }, "b" : { "x" : 1732, "y" : 696 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 1726, "y" : 690 } } } } ] }, { "id" : 30992, "reactomeId" : 10016797, "displayName" : "Lysosome Destined Cargo:AP-1:Beta-arrestin:Vamp:Clathrin Triskelion:Dynamin:Endophilin Complex", "schemaClass" : "Complex", "renderableClass" : "Complex", "position" : { "x" : 1857, "y" : 856 }, "minX" : 1794, "maxX" : 2014, "minY" : 759, "maxY" : 902, "prop" : { "x" : 1794, "y" : 810, "width" : 127, "height" : 92 }, "textPosition" : { "x" : 1794, "y" : 783 }, "bgColor" : { "r" : 204, "g" : 255, "b" : 255 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1921, "y" : 810 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1921, "y" : 810 } } }, "connectors" : [ { "edgeId" : 30988, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 1832, "y" : 807 }, "to" : { "x" : 1806, "y" : 759 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 1825, "y" : 803 }, "b" : { "x" : 1832, "y" : 807 }, "c" : { "x" : 1832, "y" : 799 }, "type" : "ARROW", "centre" : { "x" : 1832, "y" : 799 } } }, { "edgeId" : 30995, "type" : "INPUT", "segments" : [ { "from" : { "x" : 1924, "y" : 840 }, "to" : { "x" : 2014, "y" : 818 } } ], "stoichiometry" : { "value" : 1 } }, { "edgeId" : 30995, "type" : "CATALYST", "segments" : [ { "from" : { "x" : 1863, "y" : 807 }, "to" : { "x" : 1867, "y" : 789 } }, { "from" : { "x" : 1867, "y" : 789 }, "to" : { "x" : 1999, "y" : 790 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "c" : { "x" : 2003, "y" : 790 }, "r" : 4, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 2003, "y" : 790 } } } ] }, { "id" : 30993, "reactomeId" : 29372, "displayName" : "Pi", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 1889, "y" : 686 }, "minX" : 1806, "maxX" : 2013, "minY" : 665, "maxY" : 759, "prop" : { "x" : 1876, "y" : 671, "width" : 27, "height" : 30 }, "textPosition" : { "x" : 1880, "y" : 675 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1898, "y" : 676 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1898, "y" : 676 } } }, "connectors" : [ { "edgeId" : 30988, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 1873, "y" : 697 }, "to" : { "x" : 1806, "y" : 759 } } ], "stoichiometry" : { "value" : 52, "shape" : { "a" : { "x" : 1833, "y" : 722 }, "b" : { "x" : 1845, "y" : 734 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 1839, "y" : 728 } } }, "endShape" : { "a" : { "x" : 1871, "y" : 705 }, "b" : { "x" : 1873, "y" : 697 }, "c" : { "x" : 1865, "y" : 699 }, "type" : "ARROW", "centre" : { "x" : 1865, "y" : 699 } } }, { "edgeId" : 30995, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 1906, "y" : 683 }, "to" : { "x" : 2013, "y" : 665 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 1912, "y" : 678 }, "b" : { "x" : 1906, "y" : 683 }, "c" : { "x" : 1913, "y" : 686 }, "type" : "ARROW", "centre" : { "x" : 1913, "y" : 686 } } } ] }, { "id" : 30994, "reactomeId" : 10008011, "displayName" : "Arf1-GDP", "schemaClass" : "Complex", "renderableClass" : "Complex", "position" : { "x" : 1965, "y" : 754 }, "minX" : 1806, "maxX" : 2004, "minY" : 737, "maxY" : 765, "prop" : { "x" : 1932, "y" : 743, "width" : 66, "height" : 22 }, "textPosition" : { "x" : 1933, "y" : 744 }, "bgColor" : { "r" : 204, "g" : 255, "b" : 255 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1998, "y" : 743 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1998, "y" : 743 } } }, "connectors" : [ { "edgeId" : 30988, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 1929, "y" : 755 }, "to" : { "x" : 1806, "y" : 759 } } ], "stoichiometry" : { "value" : 52, "shape" : { "a" : { "x" : 1861, "y" : 751 }, "b" : { "x" : 1873, "y" : 763 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 1867, "y" : 757 } } }, "endShape" : { "a" : { "x" : 1922, "y" : 759 }, "b" : { "x" : 1929, "y" : 755 }, "c" : { "x" : 1922, "y" : 751 }, "type" : "ARROW", "centre" : { "x" : 1922, "y" : 751 } } } ] }, { "id" : 30996, "reactomeId" : 29438, "displayName" : "GTP", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 2055, "y" : 840 }, "minX" : 2014, "maxX" : 2077, "minY" : 818, "maxY" : 855, "prop" : { "x" : 2035, "y" : 825, "width" : 41, "height" : 30 }, "textPosition" : { "x" : 2039, "y" : 829 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 2071, "y" : 830 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 2071, "y" : 830 } } }, "connectors" : [ { "edgeId" : 30995, "type" : "INPUT", "segments" : [ { "from" : { "x" : 2032, "y" : 829 }, "to" : { "x" : 2014, "y" : 818 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 30997, "reactomeId" : 10016773, "displayName" : "Lysosome Cargo:AP-1:Beta-arrestin:Clathrin Triskelion:Vamp Complex", "schemaClass" : "Complex", "renderableClass" : "Complex", "position" : { "x" : 1681, "y" : 496 }, "minX" : 1592, "maxX" : 2013, "minY" : 452, "maxY" : 665, "prop" : { "x" : 1617, "y" : 464, "width" : 129, "height" : 64 }, "textPosition" : { "x" : 1618, "y" : 465 }, "bgColor" : { "r" : 204, "g" : 255, "b" : 255 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1746, "y" : 464 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1746, "y" : 464 } } }, "connectors" : [ { "edgeId" : 30995, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 1749, "y" : 521 }, "to" : { "x" : 1824, "y" : 552 } }, { "from" : { "x" : 1824, "y" : 552 }, "to" : { "x" : 2013, "y" : 665 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 1757, "y" : 520 }, "b" : { "x" : 1749, "y" : 521 }, "c" : { "x" : 1754, "y" : 527 }, "type" : "ARROW", "centre" : { "x" : 1754, "y" : 527 } } }, { "edgeId" : 30999, "type" : "INPUT", "segments" : [ { "from" : { "x" : 1614, "y" : 464 }, "to" : { "x" : 1592, "y" : 452 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 30998, "reactomeId" : 29420, "displayName" : "GDP", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 2015, "y" : 614 }, "minX" : 1994, "maxX" : 2037, "minY" : 598, "maxY" : 665, "prop" : { "x" : 1994, "y" : 599, "width" : 42, "height" : 30 }, "textPosition" : { "x" : 1998, "y" : 603 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 2031, "y" : 604 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 2031, "y" : 604 } } }, "connectors" : [ { "edgeId" : 30995, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 2014, "y" : 632 }, "to" : { "x" : 2013, "y" : 665 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 2018, "y" : 639 }, "b" : { "x" : 2014, "y" : 632 }, "c" : { "x" : 2010, "y" : 639 }, "type" : "ARROW", "centre" : { "x" : 2010, "y" : 639 } } } ] }, { "id" : 31000, "reactomeId" : 113592, "displayName" : "ATP", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 1593, "y" : 571 }, "minX" : 1573, "maxX" : 1614, "minY" : 452, "maxY" : 586, "prop" : { "x" : 1573, "y" : 556, "width" : 40, "height" : 30 }, "textPosition" : { "x" : 1577, "y" : 560 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1608, "y" : 561 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1608, "y" : 561 } } }, "connectors" : [ { "edgeId" : 30999, "type" : "INPUT", "segments" : [ { "from" : { "x" : 1592, "y" : 553 }, "to" : { "x" : 1592, "y" : 452 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 31001, "reactomeId" : 10015163, "displayName" : "HSC70:Auxillin Complex", "schemaClass" : "Complex", "renderableClass" : "Complex", "position" : { "x" : 1508, "y" : 495 }, "minX" : 1460, "maxX" : 1592, "minY" : 342, "maxY" : 513, "prop" : { "x" : 1460, "y" : 477, "width" : 97, "height" : 36 }, "textPosition" : { "x" : 1459, "y" : 478 }, "bgColor" : { "r" : 204, "g" : 255, "b" : 255 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1557, "y" : 477 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1557, "y" : 477 } } }, "connectors" : [ { "edgeId" : 30999, "type" : "INPUT", "segments" : [ { "from" : { "x" : 1543, "y" : 474 }, "to" : { "x" : 1592, "y" : 452 } } ], "stoichiometry" : { "value" : 1 } }, { "edgeId" : 30999, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 1517, "y" : 474 }, "to" : { "x" : 1590, "y" : 342 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 1517, "y" : 466 }, "b" : { "x" : 1517, "y" : 474 }, "c" : { "x" : 1524, "y" : 470 }, "type" : "ARROW", "centre" : { "x" : 1524, "y" : 470 } } } ] }, { "id" : 31002, "reactomeId" : 10016771, "displayName" : "Lysosome Cargo", "schemaClass" : "CandidateSet", "renderableClass" : "EntitySet", "position" : { "x" : 1707, "y" : 362 }, "minX" : 1590, "maxX" : 1759, "minY" : 341, "maxY" : 373, "prop" : { "x" : 1656, "y" : 351, "width" : 103, "height" : 22 }, "textPosition" : { "x" : 1671, "y" : 345 }, "connectors" : [ { "edgeId" : 30999, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 1650, "y" : 353 }, "to" : { "x" : 1590, "y" : 342 } } ], "stoichiometry" : { "value" : 52, "shape" : { "a" : { "x" : 1614, "y" : 341 }, "b" : { "x" : 1626, "y" : 353 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 1620, "y" : 347 } } }, "endShape" : { "a" : { "x" : 1642, "y" : 356 }, "b" : { "x" : 1650, "y" : 353 }, "c" : { "x" : 1644, "y" : 348 }, "type" : "ARROW", "centre" : { "x" : 1644, "y" : 348 } } } ] }, { "id" : 31003, "reactomeId" : 29370, "displayName" : "ADP", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 1515, "y" : 273 }, "minX" : 1495, "maxX" : 1590, "minY" : 257, "maxY" : 342, "prop" : { "x" : 1495, "y" : 258, "width" : 41, "height" : 30 }, "textPosition" : { "x" : 1499, "y" : 262 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1531, "y" : 263 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1531, "y" : 263 } } }, "connectors" : [ { "edgeId" : 30999, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 1531, "y" : 291 }, "to" : { "x" : 1590, "y" : 342 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 1539, "y" : 293 }, "b" : { "x" : 1531, "y" : 291 }, "c" : { "x" : 1534, "y" : 299 }, "type" : "ARROW", "centre" : { "x" : 1534, "y" : 299 } } } ] }, { "id" : 31004, "reactomeId" : 10016731, "displayName" : "Vamp", "schemaClass" : "CandidateSet", "renderableClass" : "EntitySet", "position" : { "x" : 1670, "y" : 280 }, "minX" : 1590, "maxX" : 1692, "minY" : 269, "maxY" : 342, "prop" : { "x" : 1649, "y" : 269, "width" : 43, "height" : 22 }, "textPosition" : { "x" : 1649, "y" : 269 }, "connectors" : [ { "edgeId" : 30999, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 1655, "y" : 297 }, "to" : { "x" : 1590, "y" : 342 } } ], "stoichiometry" : { "value" : 52, "shape" : { "a" : { "x" : 1616, "y" : 313 }, "b" : { "x" : 1628, "y" : 325 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 1622, "y" : 319 } } }, "endShape" : { "a" : { "x" : 1652, "y" : 304 }, "b" : { "x" : 1655, "y" : 297 }, "c" : { "x" : 1647, "y" : 298 }, "type" : "ARROW", "centre" : { "x" : 1647, "y" : 298 } } } ] }, { "id" : 31005, "reactomeId" : 29372, "displayName" : "Pi", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 1570, "y" : 257 }, "minX" : 1557, "maxX" : 1590, "minY" : 241, "maxY" : 342, "prop" : { "x" : 1557, "y" : 242, "width" : 27, "height" : 30 }, "textPosition" : { "x" : 1561, "y" : 246 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1579, "y" : 247 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1579, "y" : 247 } } }, "connectors" : [ { "edgeId" : 30999, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 1573, "y" : 275 }, "to" : { "x" : 1590, "y" : 342 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 1579, "y" : 281 }, "b" : { "x" : 1573, "y" : 275 }, "c" : { "x" : 1571, "y" : 283 }, "type" : "ARROW", "centre" : { "x" : 1571, "y" : 283 } } } ] }, { "id" : 31006, "reactomeId" : 10016737, "displayName" : "Lysosome Cargo", "schemaClass" : "CandidateSet", "renderableClass" : "EntitySet", "position" : { "x" : 1718, "y" : 318 }, "minX" : 1590, "maxX" : 1770, "minY" : 307, "maxY" : 342, "prop" : { "x" : 1667, "y" : 307, "width" : 103, "height" : 22 }, "textPosition" : { "x" : 1682, "y" : 301 }, "connectors" : [ { "edgeId" : 30999, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 1661, "y" : 327 }, "to" : { "x" : 1590, "y" : 342 } } ], "stoichiometry" : { "value" : 52, "shape" : { "a" : { "x" : 1619, "y" : 328 }, "b" : { "x" : 1631, "y" : 340 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 1625, "y" : 334 } } }, "endShape" : { "a" : { "x" : 1655, "y" : 332 }, "b" : { "x" : 1661, "y" : 327 }, "c" : { "x" : 1653, "y" : 325 }, "type" : "ARROW", "centre" : { "x" : 1653, "y" : 325 } } } ] }, { "id" : 31007, "reactomeId" : 10015069, "displayName" : "AP-1 Complex", "schemaClass" : "Complex", "renderableClass" : "Complex", "position" : { "x" : 1474, "y" : 395 }, "minX" : 1427, "maxX" : 1590, "minY" : 342, "maxY" : 406, "prop" : { "x" : 1427, "y" : 384, "width" : 94, "height" : 22 }, "textPosition" : { "x" : 1428, "y" : 385 }, "bgColor" : { "r" : 204, "g" : 255, "b" : 255 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1521, "y" : 384 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1521, "y" : 384 } } }, "connectors" : [ { "edgeId" : 30999, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 1498, "y" : 381 }, "to" : { "x" : 1590, "y" : 342 } } ], "stoichiometry" : { "value" : 52, "shape" : { "a" : { "x" : 1538, "y" : 355 }, "b" : { "x" : 1550, "y" : 367 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 1544, "y" : 361 } } }, "endShape" : { "a" : { "x" : 1503, "y" : 375 }, "b" : { "x" : 1498, "y" : 381 }, "c" : { "x" : 1506, "y" : 382 }, "type" : "ARROW", "centre" : { "x" : 1506, "y" : 382 } } } ] }, { "id" : 31008, "reactomeId" : 5632461, "displayName" : "Arrb1", "schemaClass" : "EntityWithAccessionedSequence", "renderableClass" : "Protein", "position" : { "x" : 1452, "y" : 349 }, "minX" : 1428, "maxX" : 1590, "minY" : 332, "maxY" : 360, "prop" : { "x" : 1428, "y" : 338, "width" : 48, "height" : 22 }, "textPosition" : { "x" : 1431, "y" : 338 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1476, "y" : 338 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1476, "y" : 338 } } }, "connectors" : [ { "edgeId" : 30999, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 1479, "y" : 347 }, "to" : { "x" : 1590, "y" : 342 } } ], "stoichiometry" : { "value" : 52, "shape" : { "a" : { "x" : 1528, "y" : 338 }, "b" : { "x" : 1540, "y" : 350 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 1534, "y" : 344 } } }, "endShape" : { "a" : { "x" : 1486, "y" : 343 }, "b" : { "x" : 1479, "y" : 347 }, "c" : { "x" : 1486, "y" : 351 }, "type" : "ARROW", "centre" : { "x" : 1486, "y" : 351 } } } ] }, { "id" : 31009, "reactomeId" : 10015037, "displayName" : "Clathrin Triskelion", "schemaClass" : "Complex", "renderableClass" : "Complex", "position" : { "x" : 1454, "y" : 312 }, "minX" : 1398, "maxX" : 1590, "minY" : 295, "maxY" : 342, "prop" : { "x" : 1398, "y" : 301, "width" : 113, "height" : 22 }, "textPosition" : { "x" : 1421, "y" : 288 }, "bgColor" : { "r" : 204, "g" : 255, "b" : 255 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1511, "y" : 301 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1511, "y" : 301 } } }, "connectors" : [ { "edgeId" : 30999, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 1503, "y" : 326 }, "to" : { "x" : 1590, "y" : 342 } } ], "stoichiometry" : { "value" : 48, "shape" : { "a" : { "x" : 1540, "y" : 328 }, "b" : { "x" : 1552, "y" : 340 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 1546, "y" : 334 } } }, "endShape" : { "a" : { "x" : 1511, "y" : 323 }, "b" : { "x" : 1503, "y" : 326 }, "c" : { "x" : 1509, "y" : 331 }, "type" : "ARROW", "centre" : { "x" : 1509, "y" : 331 } } } ] }, { "id" : 31011, "reactomeId" : 10009768, "displayName" : "Snap23", "schemaClass" : "EntityWithAccessionedSequence", "renderableClass" : "Protein", "position" : { "x" : 572, "y" : 18 }, "minX" : 474, "maxX" : 606, "minY" : 1, "maxY" : 228, "prop" : { "x" : 545, "y" : 7, "width" : 55, "height" : 22 }, "textPosition" : { "x" : 548, "y" : 1 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 600, "y" : 7 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 600, "y" : 7 } } }, "connectors" : [ { "edgeId" : 31010, "type" : "INPUT", "segments" : [ { "from" : { "x" : 570, "y" : 32 }, "to" : { "x" : 554, "y" : 136 } }, { "from" : { "x" : 554, "y" : 136 }, "to" : { "x" : 475, "y" : 228 } } ], "stoichiometry" : { "value" : 1 } }, { "edgeId" : 31010, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 562, "y" : 32 }, "to" : { "x" : 474, "y" : 129 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 560, "y" : 40 }, "b" : { "x" : 562, "y" : 32 }, "c" : { "x" : 554, "y" : 34 }, "type" : "ARROW", "centre" : { "x" : 554, "y" : 34 } } } ] }, { "id" : 31012, "reactomeId" : 10009770, "displayName" : "Stx4", "schemaClass" : "EntityWithAccessionedSequence", "renderableClass" : "Protein", "position" : { "x" : 365, "y" : 21 }, "minX" : 250, "maxX" : 475, "minY" : 4, "maxY" : 228, "prop" : { "x" : 346, "y" : 10, "width" : 39, "height" : 22 }, "textPosition" : { "x" : 348, "y" : 10 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 385, "y" : 10 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 385, "y" : 10 } } }, "connectors" : [ { "edgeId" : 31010, "type" : "INPUT", "segments" : [ { "from" : { "x" : 367, "y" : 35 }, "to" : { "x" : 391, "y" : 139 } }, { "from" : { "x" : 391, "y" : 139 }, "to" : { "x" : 475, "y" : 228 } } ], "stoichiometry" : { "value" : 1 } }, { "edgeId" : 31010, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 376, "y" : 35 }, "to" : { "x" : 474, "y" : 129 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 384, "y" : 37 }, "b" : { "x" : 376, "y" : 35 }, "c" : { "x" : 378, "y" : 43 }, "type" : "ARROW", "centre" : { "x" : 378, "y" : 43 } } }, { "edgeId" : 31016, "type" : "INPUT", "segments" : [ { "from" : { "x" : 362, "y" : 35 }, "to" : { "x" : 337, "y" : 145 } }, { "from" : { "x" : 337, "y" : 145 }, "to" : { "x" : 250, "y" : 213 } } ], "stoichiometry" : { "value" : 1 } }, { "edgeId" : 31016, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 353, "y" : 35 }, "to" : { "x" : 253, "y" : 126 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 351, "y" : 43 }, "b" : { "x" : 353, "y" : 35 }, "c" : { "x" : 345, "y" : 37 }, "type" : "ARROW", "centre" : { "x" : 345, "y" : 37 } } } ] }, { "id" : 31013, "reactomeId" : 10009783, "displayName" : "Vamp2", "schemaClass" : "EntityWithAccessionedSequence", "renderableClass" : "Protein", "position" : { "x" : 476, "y" : 263 }, "minX" : 451, "maxX" : 507, "minY" : 228, "maxY" : 274, "prop" : { "x" : 451, "y" : 252, "width" : 50, "height" : 22 }, "textPosition" : { "x" : 454, "y" : 246 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 501, "y" : 252 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 501, "y" : 252 } } }, "connectors" : [ { "edgeId" : 31010, "type" : "INPUT", "segments" : [ { "from" : { "x" : 475, "y" : 249 }, "to" : { "x" : 475, "y" : 228 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 31014, "reactomeId" : 10006572, "displayName" : "Vamp2", "schemaClass" : "EntityWithAccessionedSequence", "renderableClass" : "Protein", "position" : { "x" : 473, "y" : 17 }, "minX" : 448, "maxX" : 504, "minY" : 0, "maxY" : 129, "prop" : { "x" : 448, "y" : 6, "width" : 50, "height" : 22 }, "textPosition" : { "x" : 451, "y" : 0 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 498, "y" : 6 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 498, "y" : 6 } } }, "connectors" : [ { "edgeId" : 31010, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 473, "y" : 31 }, "to" : { "x" : 474, "y" : 129 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 477, "y" : 38 }, "b" : { "x" : 473, "y" : 31 }, "c" : { "x" : 469, "y" : 38 }, "type" : "ARROW", "centre" : { "x" : 469, "y" : 38 } } } ] }, { "id" : 31015, "reactomeId" : 10009785, "displayName" : "Vamp2:SNAP23:Syn4 Secretory granule docking and fusion complex", "schemaClass" : "Complex", "renderableClass" : "Complex", "position" : { "x" : 366, "y" : 243 }, "minX" : 301, "maxX" : 467, "minY" : 155, "maxY" : 275, "prop" : { "x" : 301, "y" : 211, "width" : 131, "height" : 64 }, "textPosition" : { "x" : 302, "y" : 212 }, "bgColor" : { "r" : 204, "g" : 255, "b" : 255 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 432, "y" : 211 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 432, "y" : 211 } } }, "connectors" : [ { "edgeId" : 31010, "type" : "CATALYST", "segments" : [ { "from" : { "x" : 364, "y" : 208 }, "to" : { "x" : 362, "y" : 160 } }, { "from" : { "x" : 362, "y" : 160 }, "to" : { "x" : 459, "y" : 159 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "c" : { "x" : 463, "y" : 159 }, "r" : 4, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 463, "y" : 159 } } } ] }, { "id" : 31017, "reactomeId" : 10009774, "displayName" : "Vamp8", "schemaClass" : "EntityWithAccessionedSequence", "renderableClass" : "Protein", "position" : { "x" : 250, "y" : 259 }, "minX" : 225, "maxX" : 281, "minY" : 213, "maxY" : 270, "prop" : { "x" : 225, "y" : 248, "width" : 50, "height" : 22 }, "textPosition" : { "x" : 228, "y" : 242 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 275, "y" : 248 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 275, "y" : 248 } } }, "connectors" : [ { "edgeId" : 31016, "type" : "INPUT", "segments" : [ { "from" : { "x" : 250, "y" : 245 }, "to" : { "x" : 250, "y" : 213 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 31018, "reactomeId" : 10009768, "displayName" : "Snap23", "schemaClass" : "EntityWithAccessionedSequence", "renderableClass" : "Protein", "position" : { "x" : 163, "y" : 24 }, "minX" : 136, "maxX" : 253, "minY" : 7, "maxY" : 213, "prop" : { "x" : 136, "y" : 13, "width" : 55, "height" : 22 }, "textPosition" : { "x" : 139, "y" : 7 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 191, "y" : 13 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 191, "y" : 13 } } }, "connectors" : [ { "edgeId" : 31016, "type" : "INPUT", "segments" : [ { "from" : { "x" : 163, "y" : 38 }, "to" : { "x" : 170, "y" : 140 } }, { "from" : { "x" : 170, "y" : 140 }, "to" : { "x" : 250, "y" : 213 } } ], "stoichiometry" : { "value" : 1 } }, { "edgeId" : 31016, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 172, "y" : 38 }, "to" : { "x" : 253, "y" : 126 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 180, "y" : 40 }, "b" : { "x" : 172, "y" : 38 }, "c" : { "x" : 174, "y" : 46 }, "type" : "ARROW", "centre" : { "x" : 174, "y" : 46 } } } ] }, { "id" : 31019, "reactomeId" : 10009776, "displayName" : "Vamp8", "schemaClass" : "EntityWithAccessionedSequence", "renderableClass" : "Protein", "position" : { "x" : 255, "y" : 22 }, "minX" : 230, "maxX" : 286, "minY" : 5, "maxY" : 126, "prop" : { "x" : 230, "y" : 11, "width" : 50, "height" : 22 }, "textPosition" : { "x" : 233, "y" : 5 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 280, "y" : 11 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 280, "y" : 11 } } }, "connectors" : [ { "edgeId" : 31016, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 254, "y" : 36 }, "to" : { "x" : 253, "y" : 126 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 258, "y" : 43 }, "b" : { "x" : 254, "y" : 36 }, "c" : { "x" : 250, "y" : 43 }, "type" : "ARROW", "centre" : { "x" : 250, "y" : 43 } } } ] }, { "id" : 31020, "reactomeId" : 10009778, "displayName" : "Vamp8:SNAP23:Syn4 Secretory granule docking and fusion complex", "schemaClass" : "Complex", "renderableClass" : "Complex", "position" : { "x" : 134, "y" : 247 }, "minX" : 69, "maxX" : 245, "minY" : 163, "maxY" : 279, "prop" : { "x" : 69, "y" : 215, "width" : 131, "height" : 64 }, "textPosition" : { "x" : 70, "y" : 216 }, "bgColor" : { "r" : 204, "g" : 255, "b" : 255 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 200, "y" : 215 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 200, "y" : 215 } } }, "connectors" : [ { "edgeId" : 31016, "type" : "CATALYST", "segments" : [ { "from" : { "x" : 134, "y" : 212 }, "to" : { "x" : 136, "y" : 166 } }, { "from" : { "x" : 136, "y" : 166 }, "to" : { "x" : 237, "y" : 167 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "c" : { "x" : 241, "y" : 167 }, "r" : 4, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 241, "y" : 167 } } } ] }, { "id" : 31022, "reactomeId" : 10016239, "displayName" : "Txndc5", "schemaClass" : "EntityWithAccessionedSequence", "renderableClass" : "Protein", "position" : { "x" : 1797, "y" : 397 }, "minX" : 1768, "maxX" : 1906, "minY" : 380, "maxY" : 453, "prop" : { "x" : 1768, "y" : 386, "width" : 59, "height" : 22 }, "textPosition" : { "x" : 1771, "y" : 386 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1827, "y" : 386 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1827, "y" : 386 } } }, "connectors" : [ { "edgeId" : 31021, "type" : "INPUT", "segments" : [ { "from" : { "x" : 1818, "y" : 411 }, "to" : { "x" : 1906, "y" : 453 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 31023, "reactomeId" : 10016215, "displayName" : "Napa", "schemaClass" : "EntityWithAccessionedSequence", "renderableClass" : "Protein", "position" : { "x" : 1969, "y" : 428 }, "minX" : 1906, "maxX" : 1996, "minY" : 411, "maxY" : 453, "prop" : { "x" : 1949, "y" : 417, "width" : 41, "height" : 22 }, "textPosition" : { "x" : 1949, "y" : 417 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1990, "y" : 417 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1990, "y" : 417 } } }, "connectors" : [ { "edgeId" : 31021, "type" : "INPUT", "segments" : [ { "from" : { "x" : 1946, "y" : 436 }, "to" : { "x" : 1906, "y" : 453 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 31024, "reactomeId" : 10016231, "displayName" : "Bloc1s6", "schemaClass" : "EntityWithAccessionedSequence", "renderableClass" : "Protein", "position" : { "x" : 1953, "y" : 396 }, "minX" : 1906, "maxX" : 1990, "minY" : 379, "maxY" : 453, "prop" : { "x" : 1923, "y" : 385, "width" : 61, "height" : 22 }, "textPosition" : { "x" : 1925, "y" : 385 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1984, "y" : 385 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1984, "y" : 385 } } }, "connectors" : [ { "edgeId" : 31021, "type" : "INPUT", "segments" : [ { "from" : { "x" : 1943, "y" : 410 }, "to" : { "x" : 1906, "y" : 453 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 31025, "reactomeId" : 10016235, "displayName" : "Bloc1s4", "schemaClass" : "EntityWithAccessionedSequence", "renderableClass" : "Protein", "position" : { "x" : 1995, "y" : 457 }, "minX" : 1906, "maxX" : 2032, "minY" : 440, "maxY" : 468, "prop" : { "x" : 1965, "y" : 446, "width" : 61, "height" : 22 }, "textPosition" : { "x" : 1967, "y" : 446 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 2026, "y" : 446 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 2026, "y" : 446 } } }, "connectors" : [ { "edgeId" : 31021, "type" : "INPUT", "segments" : [ { "from" : { "x" : 1962, "y" : 455 }, "to" : { "x" : 1906, "y" : 453 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 31026, "reactomeId" : 10016223, "displayName" : "Bloc1s3", "schemaClass" : "EntityWithAccessionedSequence", "renderableClass" : "Protein", "position" : { "x" : 2023, "y" : 485 }, "minX" : 1906, "maxX" : 2060, "minY" : 453, "maxY" : 496, "prop" : { "x" : 1993, "y" : 474, "width" : 61, "height" : 22 }, "textPosition" : { "x" : 1995, "y" : 474 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 2054, "y" : 474 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 2054, "y" : 474 } } }, "connectors" : [ { "edgeId" : 31021, "type" : "INPUT", "segments" : [ { "from" : { "x" : 1990, "y" : 476 }, "to" : { "x" : 1906, "y" : 453 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 31027, "reactomeId" : 10016219, "displayName" : "Bloc1s1", "schemaClass" : "EntityWithAccessionedSequence", "renderableClass" : "Protein", "position" : { "x" : 1878, "y" : 399 }, "minX" : 1848, "maxX" : 1915, "minY" : 382, "maxY" : 453, "prop" : { "x" : 1848, "y" : 388, "width" : 61, "height" : 22 }, "textPosition" : { "x" : 1850, "y" : 388 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1909, "y" : 388 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1909, "y" : 388 } } }, "connectors" : [ { "edgeId" : 31021, "type" : "INPUT", "segments" : [ { "from" : { "x" : 1883, "y" : 413 }, "to" : { "x" : 1906, "y" : 453 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 31028, "reactomeId" : 10016227, "displayName" : "Dtnbp1", "schemaClass" : "EntityWithAccessionedSequence", "renderableClass" : "Protein", "position" : { "x" : 1962, "y" : 510 }, "minX" : 1906, "maxX" : 1997, "minY" : 453, "maxY" : 521, "prop" : { "x" : 1934, "y" : 499, "width" : 57, "height" : 22 }, "textPosition" : { "x" : 1935, "y" : 499 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1991, "y" : 499 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1991, "y" : 499 } } }, "connectors" : [ { "edgeId" : 31021, "type" : "INPUT", "segments" : [ { "from" : { "x" : 1951, "y" : 496 }, "to" : { "x" : 1906, "y" : 453 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 31029, "reactomeId" : 10016241, "displayName" : "BLOC-1 Complex", "schemaClass" : "Complex", "renderableClass" : "Complex", "position" : { "x" : 1849, "y" : 491 }, "minX" : 1795, "maxX" : 1910, "minY" : 474, "maxY" : 502, "prop" : { "x" : 1795, "y" : 480, "width" : 109, "height" : 22 }, "textPosition" : { "x" : 1796, "y" : 481 }, "bgColor" : { "r" : 204, "g" : 255, "b" : 255 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1904, "y" : 480 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1904, "y" : 480 } } }, "connectors" : [ { "edgeId" : 31021, "type" : "OUTPUT", "segments" : [ ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 31031, "reactomeId" : 10016915, "displayName" : "Sh3d19", "schemaClass" : "EntityWithAccessionedSequence", "renderableClass" : "Protein", "position" : { "x" : 141, "y" : 455 }, "minX" : 113, "maxX" : 226, "minY" : 438, "maxY" : 503, "prop" : { "x" : 113, "y" : 444, "width" : 57, "height" : 22 }, "textPosition" : { "x" : 113, "y" : 444 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 170, "y" : 444 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 170, "y" : 444 } } }, "connectors" : [ { "edgeId" : 31030, "type" : "INPUT", "segments" : [ { "from" : { "x" : 160, "y" : 469 }, "to" : { "x" : 226, "y" : 503 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 31032, "reactomeId" : 10016896, "displayName" : "phospho-p-CLINT1", "schemaClass" : "EntityWithAccessionedSequence", "renderableClass" : "Protein", "position" : { "x" : 258, "y" : 433 }, "minX" : 226, "maxX" : 297, "minY" : 416, "maxY" : 503, "prop" : { "x" : 226, "y" : 422, "width" : 65, "height" : 22 }, "textPosition" : { "x" : 226, "y" : 416 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 291, "y" : 422 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 291, "y" : 422 } } }, "connectors" : [ { "edgeId" : 31030, "type" : "INPUT", "segments" : [ { "from" : { "x" : 252, "y" : 447 }, "to" : { "x" : 226, "y" : 503 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 31033, "reactomeId" : 10016907, "displayName" : "Ferritin Complex", "schemaClass" : "Complex", "renderableClass" : "Complex", "position" : { "x" : 107, "y" : 503 }, "minX" : 55, "maxX" : 226, "minY" : 486, "maxY" : 514, "prop" : { "x" : 55, "y" : 492, "width" : 104, "height" : 22 }, "textPosition" : { "x" : 77, "y" : 479 }, "bgColor" : { "r" : 204, "g" : 255, "b" : 255 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 159, "y" : 492 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 159, "y" : 492 } } }, "connectors" : [ { "edgeId" : 31030, "type" : "INPUT", "segments" : [ { "from" : { "x" : 162, "y" : 503 }, "to" : { "x" : 226, "y" : 503 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 31034, "reactomeId" : 10016911, "displayName" : "Pum1", "schemaClass" : "EntityWithAccessionedSequence", "renderableClass" : "Protein", "position" : { "x" : 157, "y" : 543 }, "minX" : 136, "maxX" : 226, "minY" : 503, "maxY" : 554, "prop" : { "x" : 136, "y" : 532, "width" : 42, "height" : 22 }, "textPosition" : { "x" : 139, "y" : 526 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 178, "y" : 532 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 178, "y" : 532 } } }, "connectors" : [ { "edgeId" : 31030, "type" : "INPUT", "segments" : [ { "from" : { "x" : 175, "y" : 529 }, "to" : { "x" : 226, "y" : 503 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 31035, "reactomeId" : 10015141, "displayName" : "Vamp", "schemaClass" : "CandidateSet", "renderableClass" : "EntitySet", "position" : { "x" : 441, "y" : 457 }, "minX" : 226, "maxX" : 719, "minY" : 374, "maxY" : 503, "prop" : { "x" : 420, "y" : 446, "width" : 43, "height" : 22 }, "textPosition" : { "x" : 420, "y" : 446 }, "connectors" : [ { "edgeId" : 31047, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 469, "y" : 450 }, "to" : { "x" : 719, "y" : 374 } } ], "stoichiometry" : { "value" : 52, "shape" : { "a" : { "x" : 588, "y" : 406 }, "b" : { "x" : 600, "y" : 418 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 594, "y" : 412 } } }, "endShape" : { "a" : { "x" : 474, "y" : 444 }, "b" : { "x" : 469, "y" : 450 }, "c" : { "x" : 477, "y" : 452 }, "type" : "ARROW", "centre" : { "x" : 477, "y" : 452 } } }, { "edgeId" : 31030, "type" : "INPUT", "segments" : [ { "from" : { "x" : 414, "y" : 459 }, "to" : { "x" : 270, "y" : 476 } }, { "from" : { "x" : 270, "y" : 476 }, "to" : { "x" : 226, "y" : 503 } } ], "stoichiometry" : { "value" : 1 } }, { "edgeId" : 31030, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 414, "y" : 464 }, "to" : { "x" : 305, "y" : 503 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 409, "y" : 470 }, "b" : { "x" : 414, "y" : 464 }, "c" : { "x" : 406, "y" : 463 }, "type" : "ARROW", "centre" : { "x" : 406, "y" : 463 } } } ] }, { "id" : 31036, "reactomeId" : 10016917, "displayName" : "Golgi-associated vesicle interacting proteins", "schemaClass" : "Complex", "renderableClass" : "Complex", "position" : { "x" : 335, "y" : 590 }, "minX" : 273, "maxX" : 403, "minY" : 503, "maxY" : 618, "prop" : { "x" : 273, "y" : 562, "width" : 124, "height" : 56 }, "textPosition" : { "x" : 272, "y" : 569 }, "bgColor" : { "r" : 204, "g" : 255, "b" : 255 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 397, "y" : 562 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 397, "y" : 562 } } }, "connectors" : [ { "edgeId" : 31030, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 325, "y" : 559 }, "to" : { "x" : 305, "y" : 503 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 319, "y" : 554 }, "b" : { "x" : 325, "y" : 559 }, "c" : { "x" : 326, "y" : 551 }, "type" : "ARROW", "centre" : { "x" : 326, "y" : 551 } } } ] }, { "id" : 31038, "reactomeId" : 10015029, "displayName" : "Golgi-associated Vesicle Destined Cargo", "schemaClass" : "CandidateSet", "renderableClass" : "EntitySet", "position" : { "x" : 1140, "y" : 915 }, "minX" : 1085, "maxX" : 1347, "minY" : 752, "maxY" : 940, "prop" : { "x" : 1085, "y" : 890, "width" : 110, "height" : 50 }, "textPosition" : { "x" : 1087, "y" : 884 }, "connectors" : [ { "edgeId" : 31037, "type" : "INPUT", "segments" : [ { "from" : { "x" : 1171, "y" : 884 }, "to" : { "x" : 1347, "y" : 752 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 31039, "reactomeId" : 10015015, "displayName" : "Golgi-associated Vesicle Destined Cargo", "schemaClass" : "CandidateSet", "renderableClass" : "EntitySet", "position" : { "x" : 1106, "y" : 839 }, "minX" : 1051, "maxX" : 1347, "minY" : 752, "maxY" : 864, "prop" : { "x" : 1051, "y" : 814, "width" : 110, "height" : 50 }, "textPosition" : { "x" : 1053, "y" : 808 }, "connectors" : [ { "edgeId" : 31037, "type" : "INPUT", "segments" : [ { "from" : { "x" : 1167, "y" : 819 }, "to" : { "x" : 1347, "y" : 752 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 31040, "reactomeId" : 10015031, "displayName" : "Cargo:AP-1:Arf1-GTP:beta-Arrestin-1:Vamp Complex", "schemaClass" : "Complex", "renderableClass" : "Complex", "position" : { "x" : 957, "y" : 848 }, "minX" : 896, "maxX" : 1024, "minY" : 715, "maxY" : 873, "prop" : { "x" : 896, "y" : 823, "width" : 122, "height" : 50 }, "textPosition" : { "x" : 896, "y" : 824 }, "bgColor" : { "r" : 204, "g" : 255, "b" : 255 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1018, "y" : 823 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1018, "y" : 823 } } }, "connectors" : [ { "edgeId" : 31041, "type" : "INPUT", "segments" : [ { "from" : { "x" : 959, "y" : 820 }, "to" : { "x" : 971, "y" : 715 } } ], "stoichiometry" : { "value" : 52, "shape" : { "a" : { "x" : 959, "y" : 761 }, "b" : { "x" : 971, "y" : 773 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 965, "y" : 767 } } } }, { "edgeId" : 31037, "type" : "OUTPUT", "segments" : [ ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 31042, "reactomeId" : 10015039, "displayName" : "DNM2", "schemaClass" : "EntityWithAccessionedSequence", "renderableClass" : "Protein", "position" : { "x" : 897, "y" : 638 }, "minX" : 770, "maxX" : 971, "minY" : 621, "maxY" : 715, "prop" : { "x" : 875, "y" : 627, "width" : 45, "height" : 22 }, "textPosition" : { "x" : 875, "y" : 627 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 920, "y" : 627 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 920, "y" : 627 } } }, "connectors" : [ { "edgeId" : 31041, "type" : "INPUT", "segments" : [ { "from" : { "x" : 907, "y" : 652 }, "to" : { "x" : 971, "y" : 715 } } ], "stoichiometry" : { "value" : 1 } }, { "edgeId" : 31058, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 872, "y" : 637 }, "to" : { "x" : 770, "y" : 633 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 865, "y" : 641 }, "b" : { "x" : 872, "y" : 637 }, "c" : { "x" : 865, "y" : 633 }, "type" : "ARROW", "centre" : { "x" : 865, "y" : 633 } } } ] }, { "id" : 31043, "reactomeId" : 9999928, "displayName" : "Sh3gl2", "schemaClass" : "EntityWithAccessionedSequence", "renderableClass" : "Protein", "position" : { "x" : 954, "y" : 588 }, "minX" : 770, "maxX" : 988, "minY" : 571, "maxY" : 715, "prop" : { "x" : 927, "y" : 577, "width" : 55, "height" : 22 }, "textPosition" : { "x" : 929, "y" : 577 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 982, "y" : 577 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 982, "y" : 577 } } }, "connectors" : [ { "edgeId" : 31041, "type" : "INPUT", "segments" : [ { "from" : { "x" : 955, "y" : 602 }, "to" : { "x" : 971, "y" : 715 } } ], "stoichiometry" : { "value" : 1 } }, { "edgeId" : 31058, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 924, "y" : 594 }, "to" : { "x" : 770, "y" : 633 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 918, "y" : 600 }, "b" : { "x" : 924, "y" : 594 }, "c" : { "x" : 916, "y" : 592 }, "type" : "ARROW", "centre" : { "x" : 916, "y" : 592 } } } ] }, { "id" : 31044, "reactomeId" : 10015047, "displayName" : "Cargo:AP-1:Beta-arrestin:Vamp:Clathrin Triskelion:Dynamin:Endophilin Complex", "schemaClass" : "Complex", "renderableClass" : "Complex", "position" : { "x" : 821, "y" : 852 }, "minX" : 741, "maxX" : 891, "minY" : 715, "maxY" : 891, "prop" : { "x" : 758, "y" : 813, "width" : 127, "height" : 78 }, "textPosition" : { "x" : 760, "y" : 800 }, "bgColor" : { "r" : 204, "g" : 255, "b" : 255 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 885, "y" : 813 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 885, "y" : 813 } } }, "connectors" : [ { "edgeId" : 31041, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 839, "y" : 810 }, "to" : { "x" : 885, "y" : 715 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 838, "y" : 802 }, "b" : { "x" : 839, "y" : 810 }, "c" : { "x" : 846, "y" : 806 }, "type" : "ARROW", "centre" : { "x" : 846, "y" : 806 } } }, { "edgeId" : 31058, "type" : "INPUT", "segments" : [ { "from" : { "x" : 778, "y" : 810 }, "to" : { "x" : 741, "y" : 779 } } ], "stoichiometry" : { "value" : 1 } }, { "edgeId" : 31058, "type" : "CATALYST", "segments" : [ { "from" : { "x" : 798, "y" : 810 }, "to" : { "x" : 757, "y" : 741 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "c" : { "x" : 755, "y" : 737 }, "r" : 4, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 755, "y" : 737 } } } ] }, { "id" : 31045, "reactomeId" : 29372, "displayName" : "Pi", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 824, "y" : 670 }, "minX" : 811, "maxX" : 885, "minY" : 654, "maxY" : 715, "prop" : { "x" : 811, "y" : 655, "width" : 27, "height" : 30 }, "textPosition" : { "x" : 815, "y" : 659 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 833, "y" : 660 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 833, "y" : 660 } } }, "connectors" : [ { "edgeId" : 31041, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 841, "y" : 679 }, "to" : { "x" : 885, "y" : 715 } } ], "stoichiometry" : { "value" : 52, "shape" : { "a" : { "x" : 857, "y" : 691 }, "b" : { "x" : 869, "y" : 703 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 863, "y" : 697 } } }, "endShape" : { "a" : { "x" : 849, "y" : 680 }, "b" : { "x" : 841, "y" : 679 }, "c" : { "x" : 844, "y" : 686 }, "type" : "ARROW", "centre" : { "x" : 844, "y" : 686 } } } ] }, { "id" : 31046, "reactomeId" : 10008011, "displayName" : "Arf1-GDP", "schemaClass" : "Complex", "renderableClass" : "Complex", "position" : { "x" : 799, "y" : 733 }, "minX" : 766, "maxX" : 885, "minY" : 714, "maxY" : 744, "prop" : { "x" : 766, "y" : 722, "width" : 66, "height" : 22 }, "textPosition" : { "x" : 767, "y" : 723 }, "bgColor" : { "r" : 204, "g" : 255, "b" : 255 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 832, "y" : 722 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 832, "y" : 722 } } }, "connectors" : [ { "edgeId" : 31041, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 835, "y" : 726 }, "to" : { "x" : 885, "y" : 715 } } ], "stoichiometry" : { "value" : 52, "shape" : { "a" : { "x" : 854, "y" : 714 }, "b" : { "x" : 866, "y" : 726 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 860, "y" : 720 } } }, "endShape" : { "a" : { "x" : 841, "y" : 721 }, "b" : { "x" : 835, "y" : 726 }, "c" : { "x" : 843, "y" : 728 }, "type" : "ARROW", "centre" : { "x" : 843, "y" : 728 } } } ] }, { "id" : 31048, "reactomeId" : 10015151, "displayName" : "Cargo:AP-1:Beta-arrestin:Clathrin Triskelion:Vamp Complex", "schemaClass" : "Complex", "renderableClass" : "Complex", "position" : { "x" : 665, "y" : 568 }, "minX" : 609, "maxX" : 771, "minY" : 530, "maxY" : 633, "prop" : { "x" : 609, "y" : 536, "width" : 113, "height" : 64 }, "textPosition" : { "x" : 610, "y" : 523 }, "bgColor" : { "r" : 204, "g" : 255, "b" : 255 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 722, "y" : 536 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 722, "y" : 536 } } }, "connectors" : [ { "edgeId" : 31047, "type" : "INPUT", "segments" : [ { "from" : { "x" : 725, "y" : 552 }, "to" : { "x" : 771, "y" : 538 } } ], "stoichiometry" : { "value" : 1 } }, { "edgeId" : 31058, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 716, "y" : 603 }, "to" : { "x" : 770, "y" : 633 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 724, "y" : 603 }, "b" : { "x" : 716, "y" : 603 }, "c" : { "x" : 720, "y" : 610 }, "type" : "ARROW", "centre" : { "x" : 720, "y" : 610 } } } ] }, { "id" : 31049, "reactomeId" : 113592, "displayName" : "ATP", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 806, "y" : 567 }, "minX" : 771, "maxX" : 827, "minY" : 538, "maxY" : 582, "prop" : { "x" : 786, "y" : 552, "width" : 40, "height" : 30 }, "textPosition" : { "x" : 790, "y" : 556 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 821, "y" : 557 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 821, "y" : 557 } } }, "connectors" : [ { "edgeId" : 31047, "type" : "INPUT", "segments" : [ { "from" : { "x" : 787, "y" : 549 }, "to" : { "x" : 771, "y" : 538 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 31050, "reactomeId" : 10015163, "displayName" : "HSC70:Auxillin Complex", "schemaClass" : "Complex", "renderableClass" : "Complex", "position" : { "x" : 855, "y" : 393 }, "minX" : 719, "maxX" : 910, "minY" : 369, "maxY" : 538, "prop" : { "x" : 807, "y" : 375, "width" : 97, "height" : 36 }, "textPosition" : { "x" : 806, "y" : 376 }, "bgColor" : { "r" : 204, "g" : 255, "b" : 255 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 904, "y" : 375 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 904, "y" : 375 } } }, "connectors" : [ { "edgeId" : 31047, "type" : "INPUT", "segments" : [ { "from" : { "x" : 844, "y" : 414 }, "to" : { "x" : 771, "y" : 538 } } ], "stoichiometry" : { "value" : 1 } }, { "edgeId" : 31047, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 804, "y" : 386 }, "to" : { "x" : 719, "y" : 374 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 797, "y" : 389 }, "b" : { "x" : 804, "y" : 386 }, "c" : { "x" : 798, "y" : 381 }, "type" : "ARROW", "centre" : { "x" : 798, "y" : 381 } } } ] }, { "id" : 31051, "reactomeId" : 29370, "displayName" : "ADP", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 643, "y" : 349 }, "minX" : 623, "maxX" : 719, "minY" : 333, "maxY" : 374, "prop" : { "x" : 623, "y" : 334, "width" : 41, "height" : 30 }, "textPosition" : { "x" : 627, "y" : 338 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 659, "y" : 339 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 659, "y" : 339 } } }, "connectors" : [ { "edgeId" : 31047, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 667, "y" : 355 }, "to" : { "x" : 719, "y" : 374 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 675, "y" : 354 }, "b" : { "x" : 667, "y" : 355 }, "c" : { "x" : 672, "y" : 361 }, "type" : "ARROW", "centre" : { "x" : 672, "y" : 361 } } } ] }, { "id" : 31052, "reactomeId" : 10015137, "displayName" : "Golgi-associated Vesicle Cargo", "schemaClass" : "CandidateSet", "renderableClass" : "EntitySet", "position" : { "x" : 699, "y" : 475 }, "minX" : 644, "maxX" : 754, "minY" : 374, "maxY" : 493, "prop" : { "x" : 644, "y" : 457, "width" : 110, "height" : 36 }, "textPosition" : { "x" : 652, "y" : 451 }, "connectors" : [ { "edgeId" : 31047, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 702, "y" : 451 }, "to" : { "x" : 719, "y" : 374 } } ], "stoichiometry" : { "value" : 52, "shape" : { "a" : { "x" : 704, "y" : 406 }, "b" : { "x" : 716, "y" : 418 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 710, "y" : 412 } } }, "endShape" : { "a" : { "x" : 700, "y" : 443 }, "b" : { "x" : 702, "y" : 451 }, "c" : { "x" : 707, "y" : 445 }, "type" : "ARROW", "centre" : { "x" : 707, "y" : 445 } } } ] }, { "id" : 31053, "reactomeId" : 10015149, "displayName" : "Golgi-associated Vesicle Cargo", "schemaClass" : "CandidateSet", "renderableClass" : "EntitySet", "position" : { "x" : 564, "y" : 473 }, "minX" : 509, "maxX" : 719, "minY" : 374, "maxY" : 491, "prop" : { "x" : 509, "y" : 455, "width" : 110, "height" : 36 }, "textPosition" : { "x" : 517, "y" : 449 }, "connectors" : [ { "edgeId" : 31047, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 592, "y" : 449 }, "to" : { "x" : 719, "y" : 374 } } ], "stoichiometry" : { "value" : 52, "shape" : { "a" : { "x" : 649, "y" : 405 }, "b" : { "x" : 661, "y" : 417 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 655, "y" : 411 } } }, "endShape" : { "a" : { "x" : 596, "y" : 442 }, "b" : { "x" : 592, "y" : 449 }, "c" : { "x" : 600, "y" : 449 }, "type" : "ARROW", "centre" : { "x" : 600, "y" : 449 } } } ] }, { "id" : 31054, "reactomeId" : 10015037, "displayName" : "Clathrin Triskelion", "schemaClass" : "Complex", "renderableClass" : "Complex", "position" : { "x" : 700, "y" : 263 }, "minX" : 644, "maxX" : 763, "minY" : 246, "maxY" : 374, "prop" : { "x" : 644, "y" : 252, "width" : 113, "height" : 22 }, "textPosition" : { "x" : 667, "y" : 239 }, "bgColor" : { "r" : 204, "g" : 255, "b" : 255 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 757, "y" : 252 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 757, "y" : 252 } } }, "connectors" : [ { "edgeId" : 31047, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 701, "y" : 277 }, "to" : { "x" : 719, "y" : 374 } } ], "stoichiometry" : { "value" : 48, "shape" : { "a" : { "x" : 704, "y" : 319 }, "b" : { "x" : 716, "y" : 331 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 710, "y" : 325 } } }, "endShape" : { "a" : { "x" : 706, "y" : 283 }, "b" : { "x" : 701, "y" : 277 }, "c" : { "x" : 698, "y" : 285 }, "type" : "ARROW", "centre" : { "x" : 698, "y" : 285 } } } ] }, { "id" : 31055, "reactomeId" : 10015069, "displayName" : "AP-1 Complex", "schemaClass" : "Complex", "renderableClass" : "Complex", "position" : { "x" : 777, "y" : 301 }, "minX" : 719, "maxX" : 830, "minY" : 284, "maxY" : 374, "prop" : { "x" : 730, "y" : 290, "width" : 94, "height" : 22 }, "textPosition" : { "x" : 731, "y" : 291 }, "bgColor" : { "r" : 204, "g" : 255, "b" : 255 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 824, "y" : 290 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 824, "y" : 290 } } }, "connectors" : [ { "edgeId" : 31047, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 768, "y" : 315 }, "to" : { "x" : 719, "y" : 374 } } ], "stoichiometry" : { "value" : 52, "shape" : { "a" : { "x" : 737, "y" : 338 }, "b" : { "x" : 749, "y" : 350 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 743, "y" : 344 } } }, "endShape" : { "a" : { "x" : 767, "y" : 323 }, "b" : { "x" : 768, "y" : 315 }, "c" : { "x" : 760, "y" : 318 }, "type" : "ARROW", "centre" : { "x" : 760, "y" : 318 } } } ] }, { "id" : 31056, "reactomeId" : 5632461, "displayName" : "Arrb1", "schemaClass" : "EntityWithAccessionedSequence", "renderableClass" : "Protein", "position" : { "x" : 832, "y" : 339 }, "minX" : 719, "maxX" : 862, "minY" : 322, "maxY" : 374, "prop" : { "x" : 808, "y" : 328, "width" : 48, "height" : 22 }, "textPosition" : { "x" : 811, "y" : 328 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 856, "y" : 328 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 856, "y" : 328 } } }, "connectors" : [ { "edgeId" : 31047, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 805, "y" : 346 }, "to" : { "x" : 719, "y" : 374 } } ], "stoichiometry" : { "value" : 52, "shape" : { "a" : { "x" : 756, "y" : 354 }, "b" : { "x" : 768, "y" : 366 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 762, "y" : 360 } } }, "endShape" : { "a" : { "x" : 800, "y" : 352 }, "b" : { "x" : 805, "y" : 346 }, "c" : { "x" : 797, "y" : 344 }, "type" : "ARROW", "centre" : { "x" : 797, "y" : 344 } } } ] }, { "id" : 31057, "reactomeId" : 29372, "displayName" : "Pi", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 662, "y" : 309 }, "minX" : 649, "maxX" : 719, "minY" : 293, "maxY" : 374, "prop" : { "x" : 649, "y" : 294, "width" : 27, "height" : 30 }, "textPosition" : { "x" : 653, "y" : 298 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 671, "y" : 299 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 671, "y" : 299 } } }, "connectors" : [ { "edgeId" : 31047, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 675, "y" : 327 }, "to" : { "x" : 719, "y" : 374 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 683, "y" : 329 }, "b" : { "x" : 675, "y" : 327 }, "c" : { "x" : 677, "y" : 335 }, "type" : "ARROW", "centre" : { "x" : 677, "y" : 335 } } } ] }, { "id" : 31059, "reactomeId" : 29438, "displayName" : "GTP", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 710, "y" : 808 }, "minX" : 690, "maxX" : 741, "minY" : 779, "maxY" : 823, "prop" : { "x" : 690, "y" : 793, "width" : 41, "height" : 30 }, "textPosition" : { "x" : 694, "y" : 797 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 726, "y" : 798 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 726, "y" : 798 } } }, "connectors" : [ { "edgeId" : 31058, "type" : "INPUT", "segments" : [ { "from" : { "x" : 726, "y" : 790 }, "to" : { "x" : 741, "y" : 779 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 31060, "reactomeId" : 29372, "displayName" : "Pi", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 603, "y" : 655 }, "minX" : 590, "maxX" : 770, "minY" : 633, "maxY" : 670, "prop" : { "x" : 590, "y" : 640, "width" : 27, "height" : 30 }, "textPosition" : { "x" : 594, "y" : 644 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 612, "y" : 645 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 612, "y" : 645 } } }, "connectors" : [ { "edgeId" : 31058, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 620, "y" : 653 }, "to" : { "x" : 770, "y" : 633 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 626, "y" : 648 }, "b" : { "x" : 620, "y" : 653 }, "c" : { "x" : 627, "y" : 656 }, "type" : "ARROW", "centre" : { "x" : 627, "y" : 656 } } } ] }, { "id" : 31061, "reactomeId" : 29420, "displayName" : "GDP", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 665, "y" : 693 }, "minX" : 644, "maxX" : 770, "minY" : 633, "maxY" : 708, "prop" : { "x" : 644, "y" : 678, "width" : 42, "height" : 30 }, "textPosition" : { "x" : 648, "y" : 682 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 681, "y" : 683 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 681, "y" : 683 } } }, "connectors" : [ { "edgeId" : 31058, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 689, "y" : 681 }, "to" : { "x" : 770, "y" : 633 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 693, "y" : 674 }, "b" : { "x" : 689, "y" : 681 }, "c" : { "x" : 697, "y" : 681 }, "type" : "ARROW", "centre" : { "x" : 697, "y" : 681 } } } ] }, { "id" : 31063, "reactomeId" : 10053198, "displayName" : "APP(18-770)", "schemaClass" : "EntityWithAccessionedSequence", "renderableClass" : "Protein", "position" : { "x" : 373, "y" : 852 }, "minX" : 330, "maxX" : 467, "minY" : 829, "maxY" : 863, "prop" : { "x" : 330, "y" : 841, "width" : 86, "height" : 22 }, "textPosition" : { "x" : 330, "y" : 841 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 416, "y" : 841 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 416, "y" : 841 } } }, "connectors" : [ { "edgeId" : 31062, "type" : "INPUT", "segments" : [ { "from" : { "x" : 419, "y" : 841 }, "to" : { "x" : 467, "y" : 829 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 31064, "reactomeId" : 10053196, "displayName" : "AP4", "schemaClass" : "Complex", "renderableClass" : "Complex", "position" : { "x" : 450, "y" : 858 }, "minX" : 434, "maxX" : 472, "minY" : 829, "maxY" : 869, "prop" : { "x" : 434, "y" : 847, "width" : 32, "height" : 22 }, "textPosition" : { "x" : 434, "y" : 848 }, "bgColor" : { "r" : 204, "g" : 255, "b" : 255 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 466, "y" : 847 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 466, "y" : 847 } } }, "connectors" : [ { "edgeId" : 31062, "type" : "INPUT", "segments" : [ { "from" : { "x" : 456, "y" : 844 }, "to" : { "x" : 467, "y" : 829 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 31065, "reactomeId" : 10053200, "displayName" : "AP4:APP", "schemaClass" : "Complex", "renderableClass" : "Complex", "position" : { "x" : 516, "y" : 855 }, "minX" : 487, "maxX" : 551, "minY" : 771, "maxY" : 866, "prop" : { "x" : 487, "y" : 844, "width" : 58, "height" : 22 }, "textPosition" : { "x" : 498, "y" : 831 }, "bgColor" : { "r" : 204, "g" : 255, "b" : 255 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 545, "y" : 844 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 545, "y" : 844 } } }, "connectors" : [ { "edgeId" : 31062, "type" : "OUTPUT", "segments" : [ ], "stoichiometry" : { "value" : 1 } }, { "edgeId" : 31066, "type" : "INPUT", "segments" : [ ], "stoichiometry" : { "value" : 1 } }, { "edgeId" : 31066, "type" : "CATALYST", "segments" : [ { "from" : { "x" : 515, "y" : 841 }, "to" : { "x" : 511, "y" : 779 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "c" : { "x" : 511, "y" : 775 }, "r" : 4, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 511, "y" : 775 } } } ] }, { "id" : 31067, "reactomeId" : 10053214, "displayName" : "AP4:APP", "schemaClass" : "Complex", "renderableClass" : "Complex", "position" : { "x" : 452, "y" : 716 }, "minX" : 423, "maxX" : 487, "minY" : 699, "maxY" : 727, "prop" : { "x" : 423, "y" : 705, "width" : 58, "height" : 22 }, "textPosition" : { "x" : 434, "y" : 692 }, "bgColor" : { "r" : 204, "g" : 255, "b" : 255 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 481, "y" : 705 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 481, "y" : 705 } } }, "connectors" : [ { "edgeId" : 31066, "type" : "OUTPUT", "segments" : [ ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 31069, "reactomeId" : 10053825, "displayName" : "CLAT:AP1:CLVS", "schemaClass" : "Complex", "renderableClass" : "Complex", "position" : { "x" : 2014, "y" : 929 }, "minX" : 1965, "maxX" : 2108, "minY" : 350, "maxY" : 940, "prop" : { "x" : 1965, "y" : 918, "width" : 98, "height" : 22 }, "textPosition" : { "x" : 1979, "y" : 905 }, "bgColor" : { "r" : 204, "g" : 255, "b" : 255 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 2063, "y" : 918 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 2063, "y" : 918 } } }, "connectors" : [ { "edgeId" : 31068, "type" : "INPUT", "segments" : [ { "from" : { "x" : 2066, "y" : 928 }, "to" : { "x" : 2107, "y" : 928 } }, { "from" : { "x" : 2107, "y" : 928 }, "to" : { "x" : 2108, "y" : 350 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 31070, "reactomeId" : 5334668, "displayName" : "PI(3,5)P2", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 1878, "y" : 351 }, "minX" : 1843, "maxX" : 2108, "minY" : 335, "maxY" : 366, "prop" : { "x" : 1843, "y" : 336, "width" : 70, "height" : 30 }, "textPosition" : { "x" : 1845, "y" : 340 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1908, "y" : 341 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1908, "y" : 341 } } }, "connectors" : [ { "edgeId" : 31068, "type" : "INPUT", "segments" : [ { "from" : { "x" : 1916, "y" : 350 }, "to" : { "x" : 2108, "y" : 350 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 31071, "reactomeId" : 10053827, "displayName" : "CLAT:AP1:CLVS:PI(3,5)P2", "schemaClass" : "Complex", "renderableClass" : "Complex", "position" : { "x" : 1878, "y" : 289 }, "minX" : 1822, "maxX" : 1940, "minY" : 265, "maxY" : 307, "prop" : { "x" : 1822, "y" : 271, "width" : 112, "height" : 36 }, "textPosition" : { "x" : 1826, "y" : 272 }, "bgColor" : { "r" : 204, "g" : 255, "b" : 255 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1934, "y" : 271 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1934, "y" : 271 } } }, "connectors" : [ { "edgeId" : 31068, "type" : "OUTPUT", "segments" : [ ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 31073, "reactomeId" : 10059241, "displayName" : "Ap1g2", "schemaClass" : "EntityWithAccessionedSequence", "renderableClass" : "Protein", "position" : { "x" : 576, "y" : 855 }, "minX" : 552, "maxX" : 622, "minY" : 838, "maxY" : 866, "prop" : { "x" : 552, "y" : 844, "width" : 49, "height" : 22 }, "textPosition" : { "x" : 552, "y" : 844 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 601, "y" : 844 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 601, "y" : 844 } } }, "connectors" : [ { "edgeId" : 31072, "type" : "INPUT", "segments" : [ { "from" : { "x" : 604, "y" : 855 }, "to" : { "x" : 622, "y" : 855 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 31074, "reactomeId" : 10022255, "displayName" : "Chmp2a", "schemaClass" : "EntityWithAccessionedSequence", "renderableClass" : "Protein", "position" : { "x" : 568, "y" : 814 }, "minX" : 539, "maxX" : 622, "minY" : 797, "maxY" : 855, "prop" : { "x" : 539, "y" : 803, "width" : 59, "height" : 22 }, "textPosition" : { "x" : 539, "y" : 803 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 598, "y" : 803 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 598, "y" : 803 } } }, "connectors" : [ { "edgeId" : 31072, "type" : "INPUT", "segments" : [ { "from" : { "x" : 582, "y" : 828 }, "to" : { "x" : 622, "y" : 855 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 31075, "reactomeId" : 9999904, "displayName" : "HGS", "schemaClass" : "EntityWithAccessionedSequence", "renderableClass" : "Protein", "position" : { "x" : 598, "y" : 785 }, "minX" : 582, "maxX" : 622, "minY" : 768, "maxY" : 855, "prop" : { "x" : 582, "y" : 774, "width" : 33, "height" : 22 }, "textPosition" : { "x" : 585, "y" : 768 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 615, "y" : 774 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 615, "y" : 774 } } }, "connectors" : [ { "edgeId" : 31072, "type" : "INPUT", "segments" : [ { "from" : { "x" : 601, "y" : 799 }, "to" : { "x" : 622, "y" : 855 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 31076, "reactomeId" : 10059243, "displayName" : "AP1G2:HGS:CHMP2A", "schemaClass" : "Complex", "renderableClass" : "Complex", "position" : { "x" : 696, "y" : 859 }, "minX" : 656, "maxX" : 743, "minY" : 836, "maxY" : 876, "prop" : { "x" : 656, "y" : 842, "width" : 81, "height" : 34 }, "textPosition" : { "x" : 667, "y" : 827 }, "bgColor" : { "r" : 204, "g" : 255, "b" : 255 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 737, "y" : 842 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 737, "y" : 842 } } }, "connectors" : [ { "edgeId" : 31072, "type" : "OUTPUT", "segments" : [ ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 31078, "reactomeId" : 10072047, "displayName" : "GOLGB1 homodimer", "schemaClass" : "Complex", "renderableClass" : "Complex", "position" : { "x" : 64, "y" : 901 }, "minX" : 24, "maxX" : 145, "minY" : 876, "maxY" : 951, "prop" : { "x" : 24, "y" : 882, "width" : 80, "height" : 39 }, "textPosition" : { "x" : 25, "y" : 886 }, "bgColor" : { "r" : 204, "g" : 255, "b" : 255 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 104, "y" : 882 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 104, "y" : 882 } } }, "connectors" : [ { "edgeId" : 31077, "type" : "INPUT", "segments" : [ { "from" : { "x" : 95, "y" : 924 }, "to" : { "x" : 145, "y" : 951 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 31079, "reactomeId" : 10079496, "displayName" : "Acbd3", "schemaClass" : "EntityWithAccessionedSequence", "renderableClass" : "Protein", "position" : { "x" : 75, "y" : 974 }, "minX" : 51, "maxX" : 145, "minY" : 951, "maxY" : 985, "prop" : { "x" : 51, "y" : 963, "width" : 49, "height" : 22 }, "textPosition" : { "x" : 52, "y" : 963 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 100, "y" : 963 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 100, "y" : 963 } } }, "connectors" : [ { "edgeId" : 31077, "type" : "INPUT", "segments" : [ { "from" : { "x" : 103, "y" : 965 }, "to" : { "x" : 145, "y" : 951 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 31080, "reactomeId" : 10079498, "displayName" : "ACBD3:GOLGB1 dimer", "schemaClass" : "Complex", "renderableClass" : "Complex", "position" : { "x" : 251, "y" : 977 }, "minX" : 199, "maxX" : 310, "minY" : 953, "maxY" : 995, "prop" : { "x" : 199, "y" : 959, "width" : 105, "height" : 36 }, "textPosition" : { "x" : 199, "y" : 960 }, "bgColor" : { "r" : 204, "g" : 255, "b" : 255 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 304, "y" : 959 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 304, "y" : 959 } } }, "connectors" : [ { "edgeId" : 31077, "type" : "OUTPUT", "segments" : [ ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 30975, "reactomeId" : 29438, "displayName" : "GTP", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 135, "y" : 758 }, "minX" : 115, "maxX" : 157, "minY" : 742, "maxY" : 805, "prop" : { "x" : 115, "y" : 743, "width" : 41, "height" : 30 }, "textPosition" : { "x" : 119, "y" : 747 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 151, "y" : 748 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 151, "y" : 748 } } }, "connectors" : [ { "edgeId" : 30974, "type" : "INPUT", "segments" : [ { "from" : { "x" : 135, "y" : 776 }, "to" : { "x" : 135, "y" : 805 } } ], "stoichiometry" : { "value" : 1 } } ] } ], "edges" : [ { "id" : 31072, "reactomeId" : 10059245, "displayName" : "AP1G2 binds HGS and CHMP2A", "schemaClass" : "Reaction", "renderableClass" : "Reaction", "position" : { "x" : 621, "y" : 857 }, "minX" : 615, "maxX" : 653, "minY" : 851, "maxY" : 863, "reactionType" : "binding", "segments" : [ { "from" : { "x" : 622, "y" : 855 }, "to" : { "x" : 621, "y" : 857 } }, { "from" : { "x" : 621, "y" : 857 }, "to" : { "x" : 653, "y" : 857 } } ], "endShape" : { "a" : { "x" : 646, "y" : 861 }, "b" : { "x" : 653, "y" : 857 }, "c" : { "x" : 646, "y" : 853 }, "type" : "ARROW", "centre" : { "x" : 646, "y" : 853 } }, "reactionShape" : { "c" : { "x" : 621, "y" : 857 }, "r" : 5, "type" : "CIRCLE", "centre" : { "x" : 621, "y" : 857 } }, "inputs" : [ { "id" : 31073, "points" : [ { "x" : 604, "y" : 855 } ] }, { "id" : 31074, "points" : [ { "x" : 582, "y" : 828 } ] }, { "id" : 31075, "points" : [ { "x" : 601, "y" : 799 } ] } ], "outputs" : [ { "id" : 31076 } ] }, { "id" : 31041, "reactomeId" : 10015049, "displayName" : "trans-Golgi Network Coat Assembly", "schemaClass" : "Reaction", "renderableClass" : "Reaction", "position" : { "x" : 921, "y" : 715 }, "minX" : 885, "maxX" : 971, "minY" : 709, "maxY" : 721, "reactionType" : "dissociation", "segments" : [ { "from" : { "x" : 971, "y" : 715 }, "to" : { "x" : 921, "y" : 715 } }, { "from" : { "x" : 921, "y" : 715 }, "to" : { "x" : 885, "y" : 715 } } ], "reactionShape" : { "c" : { "x" : 921, "y" : 715 }, "r" : 5, "r1" : 3, "type" : "DOUBLE_CIRCLE", "empty" : true, "centre" : { "x" : 921, "y" : 715 } }, "inputs" : [ { "id" : 31040, "points" : [ { "x" : 959, "y" : 820 } ], "stoichiometry" : 52 }, { "id" : 30991, "points" : [ { "x" : 1575, "y" : 702 } ], "stoichiometry" : 48 }, { "id" : 31042, "points" : [ { "x" : 907, "y" : 652 } ] }, { "id" : 31043, "points" : [ { "x" : 955, "y" : 602 } ] } ], "outputs" : [ { "id" : 31044, "points" : [ { "x" : 839, "y" : 810 } ] }, { "id" : 31045, "points" : [ { "x" : 841, "y" : 679 } ], "stoichiometry" : 52 }, { "id" : 31046, "points" : [ { "x" : 835, "y" : 726 } ], "stoichiometry" : 52 } ] }, { "id" : 31010, "reactomeId" : 10009788, "displayName" : "Vamp2 associated secretory vesicle to plasma membrane transport", "schemaClass" : "Reaction", "renderableClass" : "Reaction", "position" : { "x" : 475, "y" : 159 }, "minX" : 469, "maxX" : 481, "minY" : 129, "maxY" : 228, "reactionType" : "transition", "segments" : [ { "from" : { "x" : 475, "y" : 228 }, "to" : { "x" : 475, "y" : 159 } }, { "from" : { "x" : 475, "y" : 159 }, "to" : { "x" : 474, "y" : 129 } } ], "reactionShape" : { "a" : { "x" : 469, "y" : 153 }, "b" : { "x" : 481, "y" : 165 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 475, "y" : 159 } }, "inputs" : [ { "id" : 31011, "points" : [ { "x" : 570, "y" : 32 }, { "x" : 554, "y" : 136 } ] }, { "id" : 31012, "points" : [ { "x" : 367, "y" : 35 }, { "x" : 391, "y" : 139 } ] }, { "id" : 31013, "points" : [ { "x" : 475, "y" : 249 } ] } ], "outputs" : [ { "id" : 31011, "points" : [ { "x" : 562, "y" : 32 } ] }, { "id" : 31012, "points" : [ { "x" : 376, "y" : 35 } ] }, { "id" : 31014, "points" : [ { "x" : 473, "y" : 31 } ] } ], "catalysts" : [ { "id" : 31015, "points" : [ { "x" : 364, "y" : 208 }, { "x" : 362, "y" : 160 } ] } ] }, { "id" : 30980, "reactomeId" : 10016804, "displayName" : "Vamp And trans-Golgi Network AP-1 Binding Coupled With Cargo Capture On Lysosome Vesicle Destined Golgi Membrane", "schemaClass" : "Reaction", "renderableClass" : "Reaction", "position" : { "x" : 1627, "y" : 790 }, "minX" : 1489, "maxX" : 1664, "minY" : 784, "maxY" : 817, "reactionType" : "binding", "segments" : [ { "from" : { "x" : 1489, "y" : 807 }, "to" : { "x" : 1627, "y" : 790 } }, { "from" : { "x" : 1627, "y" : 790 }, "to" : { "x" : 1664, "y" : 817 } } ], "endShape" : { "a" : { "x" : 1656, "y" : 816 }, "b" : { "x" : 1664, "y" : 817 }, "c" : { "x" : 1661, "y" : 810 }, "type" : "ARROW", "centre" : { "x" : 1661, "y" : 810 } }, "reactionShape" : { "c" : { "x" : 1627, "y" : 790 }, "r" : 5, "type" : "CIRCLE", "centre" : { "x" : 1627, "y" : 790 } }, "inputs" : [ { "id" : 30981, "points" : [ { "x" : 1236, "y" : 965 } ] }, { "id" : 30982, "points" : [ { "x" : 1456, "y" : 884 }, { "x" : 1470, "y" : 830 } ] }, { "id" : 30983, "points" : [ { "x" : 1528, "y" : 829 } ] }, { "id" : 30984, "points" : [ { "x" : 1456, "y" : 789 } ] }, { "id" : 30985, "points" : [ { "x" : 1367, "y" : 851 } ] }, { "id" : 30986, "points" : [ { "x" : 1531, "y" : 766 } ] } ], "outputs" : [ { "id" : 30987 } ] }, { "id" : 31077, "reactomeId" : 10079500, "displayName" : "ACBD3 binds GOLGB1", "schemaClass" : "Reaction", "renderableClass" : "Reaction", "position" : { "x" : 145, "y" : 952 }, "minX" : 139, "maxX" : 196, "minY" : 946, "maxY" : 964, "reactionType" : "binding", "segments" : [ { "from" : { "x" : 145, "y" : 951 }, "to" : { "x" : 145, "y" : 952 } }, { "from" : { "x" : 145, "y" : 952 }, "to" : { "x" : 196, "y" : 964 } } ], "endShape" : { "a" : { "x" : 188, "y" : 966 }, "b" : { "x" : 196, "y" : 964 }, "c" : { "x" : 190, "y" : 959 }, "type" : "ARROW", "centre" : { "x" : 190, "y" : 959 } }, "reactionShape" : { "c" : { "x" : 145, "y" : 952 }, "r" : 5, "type" : "CIRCLE", "centre" : { "x" : 145, "y" : 952 } }, "inputs" : [ { "id" : 31078, "points" : [ { "x" : 95, "y" : 924 } ] }, { "id" : 31079, "points" : [ { "x" : 103, "y" : 965 } ] } ], "outputs" : [ { "id" : 31080 } ] }, { "id" : 31047, "reactomeId" : 10015165, "displayName" : "trans-Golgi Network Derived Vesicle Uncoating", "schemaClass" : "Reaction", "renderableClass" : "Reaction", "position" : { "x" : 770, "y" : 418 }, "minX" : 719, "maxX" : 776, "minY" : 374, "maxY" : 538, "reactionType" : "dissociation", "segments" : [ { "from" : { "x" : 771, "y" : 538 }, "to" : { "x" : 770, "y" : 418 } }, { "from" : { "x" : 770, "y" : 418 }, "to" : { "x" : 719, "y" : 374 } } ], "reactionShape" : { "c" : { "x" : 770, "y" : 418 }, "r" : 5, "r1" : 3, "type" : "DOUBLE_CIRCLE", "empty" : true, "centre" : { "x" : 770, "y" : 418 } }, "inputs" : [ { "id" : 31048, "points" : [ { "x" : 725, "y" : 552 } ] }, { "id" : 31049, "points" : [ { "x" : 787, "y" : 549 } ] }, { "id" : 31050, "points" : [ { "x" : 844, "y" : 414 } ] } ], "outputs" : [ { "id" : 31051, "points" : [ { "x" : 667, "y" : 355 } ] }, { "id" : 31052, "points" : [ { "x" : 702, "y" : 451 } ], "stoichiometry" : 52 }, { "id" : 31053, "points" : [ { "x" : 592, "y" : 449 } ], "stoichiometry" : 52 }, { "id" : 31035, "points" : [ { "x" : 469, "y" : 450 } ], "stoichiometry" : 52 }, { "id" : 31054, "points" : [ { "x" : 701, "y" : 277 } ], "stoichiometry" : 48 }, { "id" : 31055, "points" : [ { "x" : 768, "y" : 315 } ], "stoichiometry" : 52 }, { "id" : 31056, "points" : [ { "x" : 805, "y" : 346 } ], "stoichiometry" : 52 }, { "id" : 31050, "points" : [ { "x" : 804, "y" : 386 } ] }, { "id" : 31057, "points" : [ { "x" : 675, "y" : 327 } ] } ] }, { "id" : 31016, "reactomeId" : 10009781, "displayName" : "Vamp8 associated secretory vesicle to plasma membrane transport", "schemaClass" : "Reaction", "renderableClass" : "Reaction", "position" : { "x" : 253, "y" : 167 }, "minX" : 247, "maxX" : 259, "minY" : 126, "maxY" : 213, "reactionType" : "transition", "segments" : [ { "from" : { "x" : 250, "y" : 213 }, "to" : { "x" : 253, "y" : 167 } }, { "from" : { "x" : 253, "y" : 167 }, "to" : { "x" : 253, "y" : 126 } } ], "reactionShape" : { "a" : { "x" : 247, "y" : 161 }, "b" : { "x" : 259, "y" : 173 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 253, "y" : 167 } }, "inputs" : [ { "id" : 31017, "points" : [ { "x" : 250, "y" : 245 } ] }, { "id" : 31012, "points" : [ { "x" : 362, "y" : 35 }, { "x" : 337, "y" : 145 } ] }, { "id" : 31018, "points" : [ { "x" : 163, "y" : 38 }, { "x" : 170, "y" : 140 } ] } ], "outputs" : [ { "id" : 31012, "points" : [ { "x" : 353, "y" : 35 } ] }, { "id" : 31018, "points" : [ { "x" : 172, "y" : 38 } ] }, { "id" : 31019, "points" : [ { "x" : 254, "y" : 36 } ] } ], "catalysts" : [ { "id" : 31020, "points" : [ { "x" : 134, "y" : 212 }, { "x" : 136, "y" : 166 } ] } ] }, { "id" : 30988, "reactomeId" : 10016799, "displayName" : "trans-Golgi Network Lysosome Vesicle Destined Membrane Coat Assembly", "schemaClass" : "Reaction", "renderableClass" : "Reaction", "position" : { "x" : 1777, "y" : 721 }, "minX" : 1758, "maxX" : 1806, "minY" : 686, "maxY" : 759, "reactionType" : "dissociation", "segments" : [ { "from" : { "x" : 1758, "y" : 686 }, "to" : { "x" : 1777, "y" : 721 } }, { "from" : { "x" : 1777, "y" : 721 }, "to" : { "x" : 1806, "y" : 759 } } ], "reactionShape" : { "c" : { "x" : 1777, "y" : 721 }, "r" : 5, "r1" : 3, "type" : "DOUBLE_CIRCLE", "empty" : true, "centre" : { "x" : 1777, "y" : 721 } }, "inputs" : [ { "id" : 30989, "points" : [ { "x" : 1816, "y" : 660 } ] }, { "id" : 30990, "points" : [ { "x" : 1789, "y" : 619 } ] }, { "id" : 30987, "points" : [ { "x" : 1714, "y" : 817 } ], "stoichiometry" : 52 }, { "id" : 30991, "points" : [ { "x" : 1694, "y" : 694 } ], "stoichiometry" : 48 } ], "outputs" : [ { "id" : 30992, "points" : [ { "x" : 1832, "y" : 807 } ] }, { "id" : 30993, "points" : [ { "x" : 1873, "y" : 697 } ], "stoichiometry" : 52 }, { "id" : 30994, "points" : [ { "x" : 1929, "y" : 755 } ], "stoichiometry" : 52 } ] }, { "id" : 31021, "reactomeId" : 10016243, "displayName" : "Formation Of Bloc-1 Complex", "schemaClass" : "Reaction", "renderableClass" : "Reaction", "position" : { "x" : 1908, "y" : 452 }, "minX" : 1865, "maxX" : 1914, "minY" : 446, "maxY" : 477, "reactionType" : "binding", "segments" : [ { "from" : { "x" : 1906, "y" : 453 }, "to" : { "x" : 1908, "y" : 452 } }, { "from" : { "x" : 1908, "y" : 452 }, "to" : { "x" : 1865, "y" : 477 } } ], "endShape" : { "a" : { "x" : 1869, "y" : 470 }, "b" : { "x" : 1865, "y" : 477 }, "c" : { "x" : 1873, "y" : 477 }, "type" : "ARROW", "centre" : { "x" : 1873, "y" : 477 } }, "reactionShape" : { "c" : { "x" : 1908, "y" : 452 }, "r" : 5, "type" : "CIRCLE", "centre" : { "x" : 1908, "y" : 452 } }, "inputs" : [ { "id" : 31022, "points" : [ { "x" : 1818, "y" : 411 } ] }, { "id" : 31023, "points" : [ { "x" : 1946, "y" : 436 } ] }, { "id" : 31024, "points" : [ { "x" : 1943, "y" : 410 } ] }, { "id" : 31025, "points" : [ { "x" : 1962, "y" : 455 } ] }, { "id" : 31026, "points" : [ { "x" : 1990, "y" : 476 } ] }, { "id" : 31027, "points" : [ { "x" : 1883, "y" : 413 } ] }, { "id" : 31028, "points" : [ { "x" : 1951, "y" : 496 } ] } ], "outputs" : [ { "id" : 31029 } ] }, { "id" : 31058, "reactomeId" : 10015154, "displayName" : "trans-Golgi Network Vesicle Scission", "schemaClass" : "Reaction", "renderableClass" : "Reaction", "position" : { "x" : 749, "y" : 727 }, "minX" : 741, "maxX" : 770, "minY" : 633, "maxY" : 779, "reactionType" : "transition", "segments" : [ { "from" : { "x" : 741, "y" : 779 }, "to" : { "x" : 749, "y" : 727 } }, { "from" : { "x" : 749, "y" : 727 }, "to" : { "x" : 770, "y" : 633 } } ], "reactionShape" : { "a" : { "x" : 743, "y" : 721 }, "b" : { "x" : 755, "y" : 733 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 749, "y" : 727 } }, "inputs" : [ { "id" : 31044, "points" : [ { "x" : 778, "y" : 810 } ] }, { "id" : 31059, "points" : [ { "x" : 726, "y" : 790 } ] } ], "outputs" : [ { "id" : 31048, "points" : [ { "x" : 716, "y" : 603 } ] }, { "id" : 31043, "points" : [ { "x" : 924, "y" : 594 } ] }, { "id" : 31042, "points" : [ { "x" : 872, "y" : 637 } ] }, { "id" : 31060, "points" : [ { "x" : 620, "y" : 653 } ] }, { "id" : 31061, "points" : [ { "x" : 689, "y" : 681 } ] } ], "catalysts" : [ { "id" : 31044, "points" : [ { "x" : 798, "y" : 810 } ] } ] }, { "id" : 30995, "reactomeId" : 10016802, "displayName" : "trans-Golgi Network Lysosomal Vesicle Scission", "schemaClass" : "Reaction", "renderableClass" : "Reaction", "position" : { "x" : 2015, "y" : 790 }, "minX" : 2009, "maxX" : 2021, "minY" : 665, "maxY" : 818, "reactionType" : "transition", "segments" : [ { "from" : { "x" : 2014, "y" : 818 }, "to" : { "x" : 2015, "y" : 790 } }, { "from" : { "x" : 2015, "y" : 790 }, "to" : { "x" : 2013, "y" : 665 } } ], "reactionShape" : { "a" : { "x" : 2009, "y" : 784 }, "b" : { "x" : 2021, "y" : 796 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 2015, "y" : 790 } }, "inputs" : [ { "id" : 30992, "points" : [ { "x" : 1924, "y" : 840 } ] }, { "id" : 30996, "points" : [ { "x" : 2032, "y" : 829 } ] } ], "outputs" : [ { "id" : 30989, "points" : [ { "x" : 1864, "y" : 648 } ] }, { "id" : 30990, "points" : [ { "x" : 1825, "y" : 612 } ] }, { "id" : 30997, "points" : [ { "x" : 1749, "y" : 521 }, { "x" : 1824, "y" : 552 } ] }, { "id" : 30998, "points" : [ { "x" : 2014, "y" : 632 } ] }, { "id" : 30993, "points" : [ { "x" : 1906, "y" : 683 } ] } ], "catalysts" : [ { "id" : 30992, "points" : [ { "x" : 1863, "y" : 807 }, { "x" : 1867, "y" : 789 } ] } ] }, { "id" : 31030, "reactomeId" : 10016919, "displayName" : "Recruitment Of Cytoplasmic Proteins To Vesicles", "schemaClass" : "Reaction", "renderableClass" : "Reaction", "position" : { "x" : 267, "y" : 503 }, "minX" : 226, "maxX" : 305, "minY" : 497, "maxY" : 509, "reactionType" : "binding", "segments" : [ { "from" : { "x" : 226, "y" : 503 }, "to" : { "x" : 267, "y" : 503 } }, { "from" : { "x" : 267, "y" : 503 }, "to" : { "x" : 305, "y" : 503 } } ], "reactionShape" : { "c" : { "x" : 267, "y" : 503 }, "r" : 5, "type" : "CIRCLE", "centre" : { "x" : 267, "y" : 503 } }, "inputs" : [ { "id" : 31031, "points" : [ { "x" : 160, "y" : 469 } ] }, { "id" : 31032, "points" : [ { "x" : 252, "y" : 447 } ] }, { "id" : 31033, "points" : [ { "x" : 162, "y" : 503 } ] }, { "id" : 31034, "points" : [ { "x" : 175, "y" : 529 } ] }, { "id" : 31035, "points" : [ { "x" : 414, "y" : 459 }, { "x" : 270, "y" : 476 } ] } ], "outputs" : [ { "id" : 31036, "points" : [ { "x" : 325, "y" : 559 } ] }, { "id" : 31035, "points" : [ { "x" : 414, "y" : 464 } ] } ] }, { "id" : 31062, "reactomeId" : 10053219, "displayName" : "AP4 binds APP", "schemaClass" : "Reaction", "renderableClass" : "Reaction", "position" : { "x" : 481, "y" : 835 }, "minX" : 461, "maxX" : 495, "minY" : 823, "maxY" : 841, "reactionType" : "binding", "segments" : [ { "from" : { "x" : 467, "y" : 829 }, "to" : { "x" : 481, "y" : 835 } }, { "from" : { "x" : 481, "y" : 835 }, "to" : { "x" : 495, "y" : 841 } } ], "endShape" : { "a" : { "x" : 487, "y" : 842 }, "b" : { "x" : 495, "y" : 841 }, "c" : { "x" : 490, "y" : 835 }, "type" : "ARROW", "centre" : { "x" : 490, "y" : 835 } }, "reactionShape" : { "c" : { "x" : 481, "y" : 835 }, "r" : 5, "type" : "CIRCLE", "centre" : { "x" : 481, "y" : 835 } }, "inputs" : [ { "id" : 31063, "points" : [ { "x" : 419, "y" : 841 } ] }, { "id" : 31064, "points" : [ { "x" : 456, "y" : 844 } ] } ], "outputs" : [ { "id" : 31065 } ] }, { "id" : 30999, "reactomeId" : 10016775, "displayName" : "trans-Golgi Network Derived Lysosomal Vesicle Uncoating", "schemaClass" : "Reaction", "renderableClass" : "Reaction", "position" : { "x" : 1592, "y" : 403 }, "minX" : 1586, "maxX" : 1598, "minY" : 342, "maxY" : 452, "reactionType" : "dissociation", "segments" : [ { "from" : { "x" : 1592, "y" : 452 }, "to" : { "x" : 1592, "y" : 403 } }, { "from" : { "x" : 1592, "y" : 403 }, "to" : { "x" : 1590, "y" : 342 } } ], "reactionShape" : { "c" : { "x" : 1592, "y" : 403 }, "r" : 5, "r1" : 3, "type" : "DOUBLE_CIRCLE", "empty" : true, "centre" : { "x" : 1592, "y" : 403 } }, "inputs" : [ { "id" : 30997, "points" : [ { "x" : 1614, "y" : 464 } ] }, { "id" : 31000, "points" : [ { "x" : 1592, "y" : 553 } ] }, { "id" : 31001, "points" : [ { "x" : 1543, "y" : 474 } ] } ], "outputs" : [ { "id" : 31002, "points" : [ { "x" : 1650, "y" : 353 } ], "stoichiometry" : 52 }, { "id" : 31003, "points" : [ { "x" : 1531, "y" : 291 } ] }, { "id" : 31004, "points" : [ { "x" : 1655, "y" : 297 } ], "stoichiometry" : 52 }, { "id" : 31005, "points" : [ { "x" : 1573, "y" : 275 } ] }, { "id" : 31006, "points" : [ { "x" : 1661, "y" : 327 } ], "stoichiometry" : 52 }, { "id" : 31001, "points" : [ { "x" : 1517, "y" : 474 } ] }, { "id" : 31007, "points" : [ { "x" : 1498, "y" : 381 } ], "stoichiometry" : 52 }, { "id" : 31008, "points" : [ { "x" : 1479, "y" : 347 } ], "stoichiometry" : 52 }, { "id" : 31009, "points" : [ { "x" : 1503, "y" : 326 } ], "stoichiometry" : 48 } ] }, { "id" : 31066, "reactomeId" : 10053217, "displayName" : "AP4 transports APP from trans-Golgi network to endosome lumen", "schemaClass" : "BlackBoxEvent", "renderableClass" : "Reaction", "position" : { "x" : 510, "y" : 763 }, "minX" : 465, "maxX" : 516, "minY" : 730, "maxY" : 841, "reactionType" : "omitted", "segments" : [ { "from" : { "x" : 508, "y" : 841 }, "to" : { "x" : 510, "y" : 763 } }, { "from" : { "x" : 510, "y" : 763 }, "to" : { "x" : 465, "y" : 730 } } ], "endShape" : { "a" : { "x" : 473, "y" : 731 }, "b" : { "x" : 465, "y" : 730 }, "c" : { "x" : 468, "y" : 737 }, "type" : "ARROW", "centre" : { "x" : 468, "y" : 737 } }, "reactionShape" : { "a" : { "x" : 504, "y" : 757 }, "b" : { "x" : 516, "y" : 769 }, "s" : "\\\\", "type" : "BOX", "empty" : true, "centre" : { "x" : 510, "y" : 763 } }, "inputs" : [ { "id" : 31065 } ], "outputs" : [ { "id" : 31067 } ], "catalysts" : [ { "id" : 31065, "points" : [ { "x" : 515, "y" : 841 } ] } ] }, { "id" : 31068, "reactomeId" : 10053829, "displayName" : "CLAT:AP1:CLVS bind PI(3,5)P2", "schemaClass" : "Reaction", "renderableClass" : "Reaction", "position" : { "x" : 2110, "y" : 351 }, "minX" : 1937, "maxX" : 2116, "minY" : 303, "maxY" : 357, "reactionType" : "binding", "segments" : [ { "from" : { "x" : 2108, "y" : 350 }, "to" : { "x" : 2110, "y" : 351 } }, { "from" : { "x" : 2110, "y" : 351 }, "to" : { "x" : 1937, "y" : 303 } } ], "endShape" : { "a" : { "x" : 1945, "y" : 301 }, "b" : { "x" : 1937, "y" : 303 }, "c" : { "x" : 1943, "y" : 309 }, "type" : "ARROW", "centre" : { "x" : 1943, "y" : 309 } }, "reactionShape" : { "c" : { "x" : 2110, "y" : 351 }, "r" : 5, "type" : "CIRCLE", "centre" : { "x" : 2110, "y" : 351 } }, "inputs" : [ { "id" : 31069, "points" : [ { "x" : 2066, "y" : 928 }, { "x" : 2107, "y" : 928 } ] }, { "id" : 31070, "points" : [ { "x" : 1916, "y" : 350 } ] } ], "outputs" : [ { "id" : 31071 } ] }, { "id" : 31037, "reactomeId" : 10015071, "displayName" : "Vamp And trans-Golgi Network AP-1 Binding Coupled With Cargo Capture", "schemaClass" : "Reaction", "renderableClass" : "Reaction", "position" : { "x" : 1009, "y" : 752 }, "minX" : 970, "maxX" : 1347, "minY" : 746, "maxY" : 820, "reactionType" : "binding", "segments" : [ { "from" : { "x" : 1347, "y" : 752 }, "to" : { "x" : 1009, "y" : 752 } }, { "from" : { "x" : 1009, "y" : 752 }, "to" : { "x" : 970, "y" : 820 } } ], "endShape" : { "a" : { "x" : 970, "y" : 812 }, "b" : { "x" : 970, "y" : 820 }, "c" : { "x" : 977, "y" : 816 }, "type" : "ARROW", "centre" : { "x" : 977, "y" : 816 } }, "reactionShape" : { "c" : { "x" : 1009, "y" : 752 }, "r" : 5, "type" : "CIRCLE", "centre" : { "x" : 1009, "y" : 752 } }, "inputs" : [ { "id" : 30981, "points" : [ { "x" : 1227, "y" : 965 }, { "x" : 1290, "y" : 890 } ] }, { "id" : 30985, "points" : [ { "x" : 1339, "y" : 842 } ] }, { "id" : 31038, "points" : [ { "x" : 1171, "y" : 884 } ] }, { "id" : 30984, "points" : [ { "x" : 1413, "y" : 769 } ] }, { "id" : 31039, "points" : [ { "x" : 1167, "y" : 819 } ] }, { "id" : 30986, "points" : [ { "x" : 1492, "y" : 752 } ] } ], "outputs" : [ { "id" : 31040 } ] }, { "id" : 30974, "reactomeId" : 10008022, "displayName" : "trans-Golgi Network Coat Activation", "schemaClass" : "Reaction", "renderableClass" : "Reaction", "position" : { "x" : 164, "y" : 805 }, "minX" : 135, "maxX" : 203, "minY" : 799, "maxY" : 811, "reactionType" : "transition", "segments" : [ { "from" : { "x" : 135, "y" : 805 }, "to" : { "x" : 164, "y" : 805 } }, { "from" : { "x" : 164, "y" : 805 }, "to" : { "x" : 203, "y" : 807 } } ], "reactionShape" : { "a" : { "x" : 158, "y" : 799 }, "b" : { "x" : 170, "y" : 811 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 164, "y" : 805 } }, "inputs" : [ { "id" : 30975, "points" : [ { "x" : 135, "y" : 776 } ] }, { "id" : 30976, "points" : [ { "x" : 86, "y" : 805 } ] } ], "outputs" : [ { "id" : 30977, "points" : [ { "x" : 228, "y" : 790 } ] }, { "id" : 30978, "points" : [ { "x" : 255, "y" : 838 } ] } ], "catalysts" : [ { "id" : 30979, "points" : [ { "x" : 163, "y" : 843 } ] } ] } ], "compartments" : [ { "id" : 31088, "reactomeId" : 437051, "displayName" : "cytoplasmic vesicle membrane", "schemaClass" : "Compartment", "renderableClass" : "Compartment", "position" : { "x" : 567, "y" : 503 }, "minX" : 442, "maxX" : 692, "minY" : 378, "maxY" : 628, "prop" : { "x" : 442, "y" : 378, "width" : 250, "height" : 250 }, "textPosition" : { "x" : 445, "y" : 498 }, "bgColor" : { "r" : 250, "g" : 240, "b" : 240 }, "componentIds" : [ 31035, 31048, 31053, 31052 ] }, { "id" : 31089, "reactomeId" : 171907, "displayName" : "endosome lumen", "schemaClass" : "Compartment", "renderableClass" : "Compartment", "position" : { "x" : 444, "y" : 713 }, "minX" : 365, "maxX" : 524, "minY" : 660, "maxY" : 767, "prop" : { "x" : 365, "y" : 660, "width" : 159, "height" : 107 }, "textPosition" : { "x" : 380, "y" : 673 }, "insets" : { "x" : 375, "y" : 670, "width" : 139, "height" : 87 }, "bgColor" : { "r" : 250, "g" : 240, "b" : 240 }, "componentIds" : [ 31067, 31066 ] }, { "id" : 31081, "reactomeId" : 70101, "displayName" : "cytosol", "schemaClass" : "Compartment", "renderableClass" : "Compartment", "position" : { "x" : 1098, "y" : 598 }, "minX" : 0, "maxX" : 2197, "minY" : 15, "maxY" : 1181, "prop" : { "x" : 0, "y" : 15, "width" : 2197, "height" : 1166 }, "textPosition" : { "x" : 18, "y" : 1114 }, "insets" : { "x" : 10, "y" : 25, "width" : 2177, "height" : 1146 }, "bgColor" : { "r" : 250, "g" : 240, "b" : 240 }, "componentIds" : [ 31082, 30976, 30974, 30990, 30998, 30984, 30986, 30993, 30994, 30991, 30996, 31083, 30988, 31000, 31003, 31005, 31009, 31008, 31007, 31001, 30995, 31011, 31012, 31014, 31084, 31019, 31016, 30989, 30980, 31010, 31018, 30999, 31023, 31024, 31025, 31026, 31021, 31028, 31030, 31031, 31032, 31033, 31037, 31041, 31045, 31046, 31051, 31047, 31088, 31049, 31054, 31055, 31056, 31050, 31058, 31057, 31043, 31042, 31060, 31061, 31059, 31089, 30977, 31034, 31036, 30975, 31062, 31068, 31074, 31075 ] }, { "id" : 31082, "reactomeId" : 17963, "displayName" : "Golgi lumen", "schemaClass" : "Compartment", "renderableClass" : "Compartment", "position" : { "x" : 1043, "y" : 917 }, "minX" : 66, "maxX" : 2021, "minY" : 851, "maxY" : 984, "prop" : { "x" : 66, "y" : 851, "width" : 1955, "height" : 133 }, "textPosition" : { "x" : 379, "y" : 929 }, "insets" : { "x" : 76, "y" : 861, "width" : 1935, "height" : 113 }, "bgColor" : { "r" : 250, "g" : 240, "b" : 240 }, "componentIds" : [ 30981, 30987, 30982, 30992, 30979, 30983, 30978, 30985, 31040, 31038, 31039, 31044, 31065, 31063, 31064, 31073, 31069, 31076, 31072, 31078, 31079, 31077, 31080 ] }, { "id" : 31083, "reactomeId" : 161320, "displayName" : "lysosomal lumen", "schemaClass" : "Compartment", "renderableClass" : "Compartment", "position" : { "x" : 1749, "y" : 372 }, "minX" : 1624, "maxX" : 1874, "minY" : 237, "maxY" : 507, "prop" : { "x" : 1624, "y" : 237, "width" : 250, "height" : 270 }, "textPosition" : { "x" : 1725, "y" : 435 }, "insets" : { "x" : 1634, "y" : 247, "width" : 230, "height" : 250 }, "bgColor" : { "r" : 250, "g" : 240, "b" : 240 }, "componentIds" : [ 30997, 31006, 31004, 31002, 31022, 31029, 31027, 31070, 31071 ] }, { "id" : 31084, "reactomeId" : 216813, "displayName" : "secretory granule membrane", "schemaClass" : "Compartment", "renderableClass" : "Compartment", "position" : { "x" : 294, "y" : 303 }, "minX" : 106, "maxX" : 482, "minY" : 257, "maxY" : 349, "prop" : { "x" : 106, "y" : 257, "width" : 376, "height" : 92 }, "textPosition" : { "x" : 150, "y" : 301 }, "bgColor" : { "r" : 250, "g" : 240, "b" : 240 }, "componentIds" : [ 31015, 31013, 31020, 31017 ] } ], "notes" : [ ], "links" : [ ], "shadows" : [ { "id" : 31090, "reactomeId" : 10100239, "displayName" : "Golgi Associated Vesicle Biogenesis", "schemaClass" : "Pathway", "renderableClass" : "Shadow", "position" : { "x" : 1039, "y" : 623 }, "minX" : 14, "maxX" : 2064, "minY" : 242, "maxY" : 1005, "prop" : { "x" : 14, "y" : 242, "width" : 306, "height" : 758 }, "points" : [ { "x" : 14, "y" : 242 }, { "x" : 2064, "y" : 242 }, { "x" : 2064, "y" : 1005 }, { "x" : 14, "y" : 1005 } ], "colour" : "#4684ee" }, { "id" : 31091, "reactomeId" : 10100301, "displayName" : "Lysosome Vesicle Biogenesis", "schemaClass" : "Pathway", "renderableClass" : "Shadow", "position" : { "x" : 1223, "y" : 616 }, "minX" : 320, "maxX" : 2126, "minY" : 232, "maxY" : 1000, "prop" : { "x" : 320, "y" : 232, "width" : 1806, "height" : 768 }, "points" : [ { "x" : 320, "y" : 232 }, { "x" : 2126, "y" : 232 }, { "x" : 2126, "y" : 1000 }, { "x" : 320, "y" : 1000 } ], "colour" : "#dc3912" } ], "minX" : 0, "maxX" : 2197, "minY" : 0, "maxY" : 1181, "disease" : false }